Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Articles 4561 - 4590 of 5949

Full-Text Articles in Entire DC Network

Intermuscular Adipose Tissue Is Muscle Specific And Associated With Poor Functional Performance, Lori J. Tuttle, David R. Sinacore, Michael J. Mueller Jan 2012

Intermuscular Adipose Tissue Is Muscle Specific And Associated With Poor Functional Performance, Lori J. Tuttle, David R. Sinacore, Michael J. Mueller

Open Access Publications

No abstract provided.


Gsk-3Β: A Bifunctional Role In Cell Death Pathways, Keith M. Jacobs, Sandeep R. Bhave, Daniel J. Ferraro, Jerry J. Jaboin, Dennis E. Hallahan, Dinesh Thotala Jan 2012

Gsk-3Β: A Bifunctional Role In Cell Death Pathways, Keith M. Jacobs, Sandeep R. Bhave, Daniel J. Ferraro, Jerry J. Jaboin, Dennis E. Hallahan, Dinesh Thotala

Open Access Publications

No abstract provided.


Auricular Point Acupressure For Chronic Low Back Pain: A Feasibility Study For 1-Week Treatment, Chao-Hsing Yeh, Lung-Chang Chien, Yi-Chien Chiang, Li-Chun Huang Jan 2012

Auricular Point Acupressure For Chronic Low Back Pain: A Feasibility Study For 1-Week Treatment, Chao-Hsing Yeh, Lung-Chang Chien, Yi-Chien Chiang, Li-Chun Huang

Open Access Publications

No abstract provided.


Postprandial Leucine And Insulin Responses And Toxicological Effects Of A Novel Whey Protein Hydrolysate-Based Supplement In Rats, Ryan G. Toedebusch, Thomas E. Childs, Shari R. Hamilton, Jan R. Crowley, Frank W. Booth, Michael D. Roberts Jan 2012

Postprandial Leucine And Insulin Responses And Toxicological Effects Of A Novel Whey Protein Hydrolysate-Based Supplement In Rats, Ryan G. Toedebusch, Thomas E. Childs, Shari R. Hamilton, Jan R. Crowley, Frank W. Booth, Michael D. Roberts

Open Access Publications

No abstract provided.


Measurement Of Apolipoprotein E And Amyloid Β Clearance Rates In The Mouse Brain Using Bolus Stable Isotope Labeling, Jacob M. Basak, Jungsu Kim, Yuriy Pyatkivskyy, Kristin R. Wildsmith, Hong Jiang, Maia Parsadanian, Bruce W. Patterson, Randall J. Bateman, David M. Holtzman Jan 2012

Measurement Of Apolipoprotein E And Amyloid Β Clearance Rates In The Mouse Brain Using Bolus Stable Isotope Labeling, Jacob M. Basak, Jungsu Kim, Yuriy Pyatkivskyy, Kristin R. Wildsmith, Hong Jiang, Maia Parsadanian, Bruce W. Patterson, Randall J. Bateman, David M. Holtzman

Open Access Publications

No abstract provided.


Comparing The Mitochondrial Genomes Of Wolbachia-Dependent And Independent Filarial Nematode Species, Samantha N. Mcnulty, Andrew S. Mullin, Jefferson A. Vaughan, Vasyl V. Tkach, Gary J. Weil, Peter U. Fischer Jan 2012

Comparing The Mitochondrial Genomes Of Wolbachia-Dependent And Independent Filarial Nematode Species, Samantha N. Mcnulty, Andrew S. Mullin, Jefferson A. Vaughan, Vasyl V. Tkach, Gary J. Weil, Peter U. Fischer

Open Access Publications

No abstract provided.


Whole Genome Sequences Of Three Treponema Pallidum Ssp. Pertenue Strains: Yaws And Syphilis Treponemes Differ In Less Than 0.2% Of The Genome Sequence, Darina Cejkova, Marie Zobanikova, Lei Chen, Petra Pospisilova, Michal Strouhal, Xiang Qin, Lenka Mikalova, Steven J. Norris, Donna M. Muzny, Richard A. Gibbs, Lucinda L. Fulton, Erica Sodergren, George M. Weinstock, David Smajs Jan 2012

Whole Genome Sequences Of Three Treponema Pallidum Ssp. Pertenue Strains: Yaws And Syphilis Treponemes Differ In Less Than 0.2% Of The Genome Sequence, Darina Cejkova, Marie Zobanikova, Lei Chen, Petra Pospisilova, Michal Strouhal, Xiang Qin, Lenka Mikalova, Steven J. Norris, Donna M. Muzny, Richard A. Gibbs, Lucinda L. Fulton, Erica Sodergren, George M. Weinstock, David Smajs

Open Access Publications

No abstract provided.


A Multicenter Evaluation Of Diagnostic Tools To Define Endpoints For Programs To Eliminate Bancroftian Filariasis, Peter U. Fischer, Ramakrishna U. Rao, Et Al Jan 2012

A Multicenter Evaluation Of Diagnostic Tools To Define Endpoints For Programs To Eliminate Bancroftian Filariasis, Peter U. Fischer, Ramakrishna U. Rao, Et Al

Open Access Publications

No abstract provided.


Role Of The Polarity Protein Scribble For Podocyte Differentiation And Maintenance, Bjorn Hartleben, Eugen Widmeier, Nicola Wanner, Miriam Schmidts, Sung Tae Kim, Lisa Schneider, Britta Mayer, Dontscho Kerjaschki, Jeffrey H. Miner, Gerd Walz, Tobias B. Huber Jan 2012

Role Of The Polarity Protein Scribble For Podocyte Differentiation And Maintenance, Bjorn Hartleben, Eugen Widmeier, Nicola Wanner, Miriam Schmidts, Sung Tae Kim, Lisa Schneider, Britta Mayer, Dontscho Kerjaschki, Jeffrey H. Miner, Gerd Walz, Tobias B. Huber

Open Access Publications

No abstract provided.


High Throughput Screening For Small Molecule Enhancers Of The Interferon Signaling Pathway To Drive Next-Generation Antiviral Drug Discovery, Dhara A. Patel, Anand C. Patel, William C. Nolan, Yong Zhang, Michael J. Holtzman Jan 2012

High Throughput Screening For Small Molecule Enhancers Of The Interferon Signaling Pathway To Drive Next-Generation Antiviral Drug Discovery, Dhara A. Patel, Anand C. Patel, William C. Nolan, Yong Zhang, Michael J. Holtzman

Open Access Publications

No abstract provided.


A Core Human Microbiome As Viewed Through 16s Rrna Sequence Clusters, Susan M. Huse, Yuzhen Ye, Yanjiao Zhou, Anthony A. Fodor Jan 2012

A Core Human Microbiome As Viewed Through 16s Rrna Sequence Clusters, Susan M. Huse, Yuzhen Ye, Yanjiao Zhou, Anthony A. Fodor

Open Access Publications

No abstract provided.


Large-Scale Pathway-Based Analysis Of Bladder Cancer Genome-Wide Association Data From Five Studies Of European Background, Gerald Andriole Jr., Et Al Jan 2012

Large-Scale Pathway-Based Analysis Of Bladder Cancer Genome-Wide Association Data From Five Studies Of European Background, Gerald Andriole Jr., Et Al

Open Access Publications

No abstract provided.


A Case Study For Large-Scale Human Microbiome Analysis Using Jcvi’S Metagenomics Reports (Metarep), Johannes Goll, Mathangi Thiagarajan, Sahar Abubucker, Curtis Huttenhower, Shibu Yooseph, Barbara A. Methe Jan 2012

A Case Study For Large-Scale Human Microbiome Analysis Using Jcvi’S Metagenomics Reports (Metarep), Johannes Goll, Mathangi Thiagarajan, Sahar Abubucker, Curtis Huttenhower, Shibu Yooseph, Barbara A. Methe

Open Access Publications

No abstract provided.


Multiple Γ-Secretase Product Peptides Are Coordinately Increased In Concentration In The Cerebrospinal Fluid Of A Subpopulation Of Sporadic Alzheimer’S Disease Subjects, Saori Hata, Miyako Taniguchi, Yi Piao, Takeshi Ikeuchi, Anne M. Fagan, David M. Holtzman, Randall Bateman, Hamid R. Sohrabi, Ralph N. Martins, Sam Gandy, Katsuya Urakami, Toshiharu Suzuki, Japanese Alzheimer's Disease Neuroimaging Initiative Jan 2012

Multiple Γ-Secretase Product Peptides Are Coordinately Increased In Concentration In The Cerebrospinal Fluid Of A Subpopulation Of Sporadic Alzheimer’S Disease Subjects, Saori Hata, Miyako Taniguchi, Yi Piao, Takeshi Ikeuchi, Anne M. Fagan, David M. Holtzman, Randall Bateman, Hamid R. Sohrabi, Ralph N. Martins, Sam Gandy, Katsuya Urakami, Toshiharu Suzuki, Japanese Alzheimer's Disease Neuroimaging Initiative

Open Access Publications

No abstract provided.


Health Related Quality Of Life Outcomes For Unresectable Stage Iii Or Iv Melanoma Patients Receiving Ipilimumab Treatment, Dennis A. Revicki, Alfons Jm Van Den Eertwegh, Paul Lorigan, Celeste Lebbe, Gerald Linette, Christian H. Ottensmeier, Shima Safikhani, Marianne Messina, Alex Hoos, Samuel Wagner, Srividya Kotapati Jan 2012

Health Related Quality Of Life Outcomes For Unresectable Stage Iii Or Iv Melanoma Patients Receiving Ipilimumab Treatment, Dennis A. Revicki, Alfons Jm Van Den Eertwegh, Paul Lorigan, Celeste Lebbe, Gerald Linette, Christian H. Ottensmeier, Shima Safikhani, Marianne Messina, Alex Hoos, Samuel Wagner, Srividya Kotapati

Open Access Publications

No abstract provided.


The Function And Evolution Of The Restriction Factor Viperin In Primates Was Not Driven By Lentiviruses, Efrem S. Lim, Lily I. Wu, Harmit S. Malik, Michael Emerman Jan 2012

The Function And Evolution Of The Restriction Factor Viperin In Primates Was Not Driven By Lentiviruses, Efrem S. Lim, Lily I. Wu, Harmit S. Malik, Michael Emerman

Open Access Publications

No abstract provided.


Unproductive Alternative Splicing And Nonsense Mrnas: A Widespread Phenomenon Among Plant Circadian Clock Genes, Sergei A. Filichkin, Todd C. Mockler Jan 2012

Unproductive Alternative Splicing And Nonsense Mrnas: A Widespread Phenomenon Among Plant Circadian Clock Genes, Sergei A. Filichkin, Todd C. Mockler

Open Access Publications

No abstract provided.


Cross-Species Genomic And Functional Analyses Identify A Combination Therapy Using A Chk1 Inhibitor And A Ribonucleotide Reductase Inhibitor To Treat Triple-Negative Breast Cancer, Christina N. Bennett, Christine C. Tomlinson, Aleksandra M. Michalowski, Isabel M. Chu, Dror Luger, Lara R. Mittereder, Olga Aprelikova, James Shou, Helen Piwnica-Worms, Melinda G. Hollingshead, Jeffrey E. Green Jan 2012

Cross-Species Genomic And Functional Analyses Identify A Combination Therapy Using A Chk1 Inhibitor And A Ribonucleotide Reductase Inhibitor To Treat Triple-Negative Breast Cancer, Christina N. Bennett, Christine C. Tomlinson, Aleksandra M. Michalowski, Isabel M. Chu, Dror Luger, Lara R. Mittereder, Olga Aprelikova, James Shou, Helen Piwnica-Worms, Melinda G. Hollingshead, Jeffrey E. Green

Open Access Publications

No abstract provided.


Adverse Metabolic Response To Regular Exercise: Is It A Rare Or Common Occurrence?, Claude Bouchard, Steven N. Blair, Timothy S. Church, Conrad P. Earnest, James M. Hagberg, Keijo Hakkinen, Nathan T. Jenkins, Laura Karavirta, William E. Kraus, Arthur S. Leon, D. C. Rao, Mark A. Sarzynski, James S. Skinner, Cris A. Slentz, Tuomo Rankinen Jan 2012

Adverse Metabolic Response To Regular Exercise: Is It A Rare Or Common Occurrence?, Claude Bouchard, Steven N. Blair, Timothy S. Church, Conrad P. Earnest, James M. Hagberg, Keijo Hakkinen, Nathan T. Jenkins, Laura Karavirta, William E. Kraus, Arthur S. Leon, D. C. Rao, Mark A. Sarzynski, James S. Skinner, Cris A. Slentz, Tuomo Rankinen

Open Access Publications

No abstract provided.


Septin 7 Forms A Complex With Cd2ap And Nephrin And Regulates Glucose Transporter Trafficking, Anita A. Wasik, Zydrune Polianskyte-Prause, Meng-Qiu Dong, Andrey S. Shaw, John R. Yates Iii, Marilyn G. Farquhar, Sanna Lehtonen Jan 2012

Septin 7 Forms A Complex With Cd2ap And Nephrin And Regulates Glucose Transporter Trafficking, Anita A. Wasik, Zydrune Polianskyte-Prause, Meng-Qiu Dong, Andrey S. Shaw, John R. Yates Iii, Marilyn G. Farquhar, Sanna Lehtonen

Open Access Publications

No abstract provided.


Ultrastructural Studies In App/Ps1 Mice Expressing Human Apoe Isoforms: Implications For Alzheimer’S Disease, Krikor Dirkranian, Jungsu Kim, Floy R. Stewart, Marilyn A. Levy, David M. Holtzman Jan 2012

Ultrastructural Studies In App/Ps1 Mice Expressing Human Apoe Isoforms: Implications For Alzheimer’S Disease, Krikor Dirkranian, Jungsu Kim, Floy R. Stewart, Marilyn A. Levy, David M. Holtzman

Open Access Publications

No abstract provided.


Accuracy Of Fall Prediction In Parkinson Disease: Six-Month And 12-Month Prospective Analyses, Ryan P. Duncan, Abigail L. Leddy, James T. Cavanaugh, Leland E. Dibble, Terry D. Ellis, Matthew P. Ford, K. B. Foreman, Gammon M. Earhart Jan 2012

Accuracy Of Fall Prediction In Parkinson Disease: Six-Month And 12-Month Prospective Analyses, Ryan P. Duncan, Abigail L. Leddy, James T. Cavanaugh, Leland E. Dibble, Terry D. Ellis, Matthew P. Ford, K. B. Foreman, Gammon M. Earhart

Open Access Publications

No abstract provided.


Co-Survival Of The Fittest Few: Mosaic Amplification Of Receptor Tyrosine Kinases In Glioblastoma, Chen Feng, Li Ding Jan 2012

Co-Survival Of The Fittest Few: Mosaic Amplification Of Receptor Tyrosine Kinases In Glioblastoma, Chen Feng, Li Ding

Open Access Publications

No abstract provided.


Ajuba Is Required For Rac Activation And Maintenance Of E-Cadherin Adhesion, Sébastien Nola, Reiko Daigaku, Kasia Smolarczyk, Maryke Carstens, Belen Martin-Martin, Gregory Longmore, Maryse Bailly, Vania M.M. Braga Nov 2011

Ajuba Is Required For Rac Activation And Maintenance Of E-Cadherin Adhesion, Sébastien Nola, Reiko Daigaku, Kasia Smolarczyk, Maryke Carstens, Belen Martin-Martin, Gregory Longmore, Maryse Bailly, Vania M.M. Braga

Open Access Publications

No abstract provided.


What's New In Orthopaedic Trauma, William M. Ricci, Christopher Mcandrew, David Merriman, Michael J. Gardner Sep 2011

What's New In Orthopaedic Trauma, William M. Ricci, Christopher Mcandrew, David Merriman, Michael J. Gardner

Open Access Publications

No abstract provided.


In Vivo Microdialysis Reveals Age-Dependent Decrease Of Brain Interstitial Fluid Tau Levels In P301s Human Tau Transgenic Mice, Kaoru Yamada, John R. Cirrito, Floy R. Stewart, Hong Jiang, Mary Beth Finn, Brandon B. Holmes, Lester I. Binder, Eva-Maria Mandelkow, Marc I. Diamond, Virginia M.-Y. Lee, David M. Holtzman Sep 2011

In Vivo Microdialysis Reveals Age-Dependent Decrease Of Brain Interstitial Fluid Tau Levels In P301s Human Tau Transgenic Mice, Kaoru Yamada, John R. Cirrito, Floy R. Stewart, Hong Jiang, Mary Beth Finn, Brandon B. Holmes, Lester I. Binder, Eva-Maria Mandelkow, Marc I. Diamond, Virginia M.-Y. Lee, David M. Holtzman

Open Access Publications

Although tau is a cytoplasmic protein, it is also found in brain extracellular fluids, e.g., CSF. Recent findings suggest that aggregated tau can be transferred between cells and extracellular tau aggregates might mediate spread of tau pathology. Despite these data, details of whether tau is normally released into the brain interstitial fluid (ISF), its concentration in ISF in relation to CSF, and whether ISF tau is influenced by its aggregation are unknown. To address these issues, we developed a microdialysis technique to analyze monomeric ISF tau levels within the hippocampus of awake, freely moving mice. We detected tau in ISF …


Spinal Reconstruction With Pedicle Screw-Based Instrumentation And Rhbmp-2 In Patients With Neurofibromatosis And Severe Dural Ectasia And Spinal Deformity: Report Of Two Cases And A Review Of The Literature, Samuel K. Cho, Geoffrey E. Stoker, Keith H. Bridwell Aug 2011

Spinal Reconstruction With Pedicle Screw-Based Instrumentation And Rhbmp-2 In Patients With Neurofibromatosis And Severe Dural Ectasia And Spinal Deformity: Report Of Two Cases And A Review Of The Literature, Samuel K. Cho, Geoffrey E. Stoker, Keith H. Bridwell

Open Access Publications

No abstract provided.


Controlled Cortical Impact Traumatic Brain Injury In 3xtg-Ad Mice Causes Acute Intra-Axonal Amyloid-Β Accumulation And Independently Accelerates The Development Of Tau Abnormalities, Hien T. Tran, Frank M. Laferla, David M. Holtzman, David L. Brody Jun 2011

Controlled Cortical Impact Traumatic Brain Injury In 3xtg-Ad Mice Causes Acute Intra-Axonal Amyloid-Β Accumulation And Independently Accelerates The Development Of Tau Abnormalities, Hien T. Tran, Frank M. Laferla, David M. Holtzman, David L. Brody

Open Access Publications

Alzheimer's disease (AD) is a neurodegenerative disorder characterized pathologically by progressive neuronal loss, extracellular plaques containing the amyloid-β (Aβ) peptides, and neurofibrillary tangles composed of hyperphosphorylated tau proteins. Aβ is thought to act upstream of tau, affecting its phosphorylation and therefore aggregation state. One of the major risk factors for AD is traumatic brain injury (TBI). Acute intra-axonal Aβ and diffuse extracellular plaques occur in ∼30% of human subjects after severe TBI. Intra-axonal accumulations of tau but not tangle-like pathologies have also been found in these patients. Whether and how these acute accumulations contribute to subsequent AD development is not …


Informatics And Data Mining Tools And Strategies For The Human Connectome Project, Daniel S. Marcus, John Harwell, Timothy Olsen, Michael Hodge, Matthew F. Glasser, Fred Prior, Mark Jenkinson, Timothy Laumann, Sandra W. Curtiss, David C. Van Essen Jun 2011

Informatics And Data Mining Tools And Strategies For The Human Connectome Project, Daniel S. Marcus, John Harwell, Timothy Olsen, Michael Hodge, Matthew F. Glasser, Fred Prior, Mark Jenkinson, Timothy Laumann, Sandra W. Curtiss, David C. Van Essen

Open Access Publications

No abstract provided.


Evaluation Of The Toxicity Of Triamcinolone Acetonide And Dexamethasone Sodium Phosphate On Human Lens Epithelial Cells (Hle B-3), Ashish Sharma, Ashkan Pirouzmanesh, Jayaprakash Patil, M. F. Estrago-Franco, Leandro Cabral Zacharias, Usha P. Andley, M. Cristina Kenney, Baruch D. Kuppermann May 2011

Evaluation Of The Toxicity Of Triamcinolone Acetonide And Dexamethasone Sodium Phosphate On Human Lens Epithelial Cells (Hle B-3), Ashish Sharma, Ashkan Pirouzmanesh, Jayaprakash Patil, M. F. Estrago-Franco, Leandro Cabral Zacharias, Usha P. Andley, M. Cristina Kenney, Baruch D. Kuppermann

Open Access Publications

No abstract provided.