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Post Hoc Analyses Of Surrogate Markers Of Non-Alcoholic Fatty Liver Disease (Nafld) And Liver Fibrosis In Patients With Type 2 Diabetes In A Digitally Supported Continuous Care Intervention: An Open-Label, Non-Randomised Controlled Study, Eduardo Vilar-Gomez, Shaminie J. Athinarayanan, Rebecca N. Adams, Sarah J. Hallberg, Nasir H. Bhanpuri, Amy L. Mckenzie, Wayne W. Campbell, James P. Mccarter, Stephen D. Phinney, Jeff S. Volek, Naga Chalasani Jan 2019

Post Hoc Analyses Of Surrogate Markers Of Non-Alcoholic Fatty Liver Disease (Nafld) And Liver Fibrosis In Patients With Type 2 Diabetes In A Digitally Supported Continuous Care Intervention: An Open-Label, Non-Randomised Controlled Study, Eduardo Vilar-Gomez, Shaminie J. Athinarayanan, Rebecca N. Adams, Sarah J. Hallberg, Nasir H. Bhanpuri, Amy L. Mckenzie, Wayne W. Campbell, James P. Mccarter, Stephen D. Phinney, Jeff S. Volek, Naga Chalasani

Open Access Publications

No abstract provided.


Implementation Of The Healthy Workplace Participatory Program In A Retail Setting: A Feasibility Study And Framework For Evaluation, Jaime R. Strickland, Anna M. Kinghorn, Bradley A. Evanoff, Ann M. Dale Jan 2019

Implementation Of The Healthy Workplace Participatory Program In A Retail Setting: A Feasibility Study And Framework For Evaluation, Jaime R. Strickland, Anna M. Kinghorn, Bradley A. Evanoff, Ann M. Dale

Open Access Publications

No abstract provided.


Consumption Of Animal-Source Protein Is Associated With Improved Height-For-Age Z Scores In Rural Malawian Children Aged 12–36 Months, Yankho Kaimila, Oscar Divala, Sophia E. Agapova, Kevin B. Stephenson, Chrissie Thakwalakwa, Indi Trehan, Mark J. Manary, Kenneth M. Maleta Jan 2019

Consumption Of Animal-Source Protein Is Associated With Improved Height-For-Age Z Scores In Rural Malawian Children Aged 12–36 Months, Yankho Kaimila, Oscar Divala, Sophia E. Agapova, Kevin B. Stephenson, Chrissie Thakwalakwa, Indi Trehan, Mark J. Manary, Kenneth M. Maleta

Open Access Publications

No abstract provided.


Whole-Genome Sequencing Of Klebsiella Pneumoniae Isolates To Track Strain Progression In A Single Patient With Recurrent Urinary Tract Infection, Kristine M. Wylie, Todd N. Wylie, Patrick J. Minx, David A. Rosen Jan 2019

Whole-Genome Sequencing Of Klebsiella Pneumoniae Isolates To Track Strain Progression In A Single Patient With Recurrent Urinary Tract Infection, Kristine M. Wylie, Todd N. Wylie, Patrick J. Minx, David A. Rosen

Open Access Publications

No abstract provided.


Operative Versus Nonoperative Treatment For Adult Symptomatic Lumbar Scoliosis, Michael P. Kelly, Elizabeth L. Yanik, Christine R. Baldus, Jacob M. Buchowski, Munish C. Gupta, Lukas P. Zebala, Keith H. Bridwell, Et Al Jan 2019

Operative Versus Nonoperative Treatment For Adult Symptomatic Lumbar Scoliosis, Michael P. Kelly, Elizabeth L. Yanik, Christine R. Baldus, Jacob M. Buchowski, Munish C. Gupta, Lukas P. Zebala, Keith H. Bridwell, Et Al

Open Access Publications

No abstract provided.


An Exome-Wide Sequencing Study Of The Goldn Cohort Reveals Novel Associations Of Coding Variants And Fasting Plasma Lipids, Ping An, Mary F. Feitosa, Michael A. Province, Et Al Jan 2019

An Exome-Wide Sequencing Study Of The Goldn Cohort Reveals Novel Associations Of Coding Variants And Fasting Plasma Lipids, Ping An, Mary F. Feitosa, Michael A. Province, Et Al

Open Access Publications

No abstract provided.


Multi-Ancestry Study Of Blood Lipid Levels Identifies Four Loci Interacting With Physical Activity, Yun Ju Sung, Karen Schwander, Lisa De Las Fuentes, Chi Charles Gu, Dabeeru C. Rao, Mary F. Feitosa, Aldi T. Kraja, Michael A. Province Jan 2019

Multi-Ancestry Study Of Blood Lipid Levels Identifies Four Loci Interacting With Physical Activity, Yun Ju Sung, Karen Schwander, Lisa De Las Fuentes, Chi Charles Gu, Dabeeru C. Rao, Mary F. Feitosa, Aldi T. Kraja, Michael A. Province

Open Access Publications

No abstract provided.


Fatty Acid 2-Hydroxylation Inhibits Tumor Growth And Increases Sensitivity To Cisplatin In Gastric Cancer, Yizhou Yao, Xiaoqin Yang, Liang Sun, Sishuo Sun, Xiaoheng Huang, Diyuan Zhou, Tingting Li, Wei Zhang, Nada A. Abumrad, Xinguo Zhu, Songbing He, Xiong Su Jan 2019

Fatty Acid 2-Hydroxylation Inhibits Tumor Growth And Increases Sensitivity To Cisplatin In Gastric Cancer, Yizhou Yao, Xiaoqin Yang, Liang Sun, Sishuo Sun, Xiaoheng Huang, Diyuan Zhou, Tingting Li, Wei Zhang, Nada A. Abumrad, Xinguo Zhu, Songbing He, Xiong Su

Open Access Publications

No abstract provided.


A Culture-Independent Analysis Of The Microbiota Of Female Interstitial Cystitis/Bladder Pain Syndrome Participants In The Mapp Research Network, J. C. Nickel, Alisa J. Stephens-Shields, J. R. Landis, Chris Mullins, Adrie Van Bokhoven, M. S. Lucia, Jeffrey P. Henderson, Bhaswati Sen, Jaroslaw E. Krol, Garth D. Ehrlich, The Mapp Research Network Jan 2019

A Culture-Independent Analysis Of The Microbiota Of Female Interstitial Cystitis/Bladder Pain Syndrome Participants In The Mapp Research Network, J. C. Nickel, Alisa J. Stephens-Shields, J. R. Landis, Chris Mullins, Adrie Van Bokhoven, M. S. Lucia, Jeffrey P. Henderson, Bhaswati Sen, Jaroslaw E. Krol, Garth D. Ehrlich, The Mapp Research Network

Open Access Publications

No abstract provided.


Associations Between Dietary Patterns And The Risk Of Breast Cancer: A Systematic Review And Meta-Analysis Of Observational Studies, Yunjun Xiao, Junjie Xia, Liping Li, Yuebin Ke, Jinquan Cheng, Yaojie Xie, Winnie Chu, Polly Cheung, Jean Hee Kim, Graham A. Colditz, Rulla M. Tamimi, Xuefen Su Jan 2019

Associations Between Dietary Patterns And The Risk Of Breast Cancer: A Systematic Review And Meta-Analysis Of Observational Studies, Yunjun Xiao, Junjie Xia, Liping Li, Yuebin Ke, Jinquan Cheng, Yaojie Xie, Winnie Chu, Polly Cheung, Jean Hee Kim, Graham A. Colditz, Rulla M. Tamimi, Xuefen Su

Open Access Publications

No abstract provided.


Comparison Of Two Models Of Family-Based Treatment For Childhood Obesity: A Pilot Study, Kristie Bergmann, Zoe Mestre, David Strong, Dawn M. Eichen, Kyung Rhee, Scott Crow, Denise Wilfley, Kerri N. Boutelle Jan 2019

Comparison Of Two Models Of Family-Based Treatment For Childhood Obesity: A Pilot Study, Kristie Bergmann, Zoe Mestre, David Strong, Dawn M. Eichen, Kyung Rhee, Scott Crow, Denise Wilfley, Kerri N. Boutelle

Open Access Publications

No abstract provided.


Fatty Acid Oxidation Promotes Cardiomyocyte Proliferation Rate But Does Not Change Cardiomyocyte Number In Infant Mice, Tongtong Cao, Daniela Liccardo, Ryan Lacanna, Xiaoying Zhang, Rong Lu, Brian N. Finck, Tani Leigh, Xiongwen Chen, Konstantinos Drosatos, Ying Tian Jan 2019

Fatty Acid Oxidation Promotes Cardiomyocyte Proliferation Rate But Does Not Change Cardiomyocyte Number In Infant Mice, Tongtong Cao, Daniela Liccardo, Ryan Lacanna, Xiaoying Zhang, Rong Lu, Brian N. Finck, Tani Leigh, Xiongwen Chen, Konstantinos Drosatos, Ying Tian

Open Access Publications

No abstract provided.


Visual Impairment And Objectively Measured Physical Activity And Sedentary Behaviour In Us Adolescents And Adults: A Cross-Sectional Study, Lee Smith, Sarah E. Jackson, Shahina Pardhan, Guillermo Felipe López-Sánchez, Liang Hu, Chao Cao, Davy Vancampfort, Ai Koyanagi, Brendon Stubbs, Joseph Firth, Lin Yang Jan 2019

Visual Impairment And Objectively Measured Physical Activity And Sedentary Behaviour In Us Adolescents And Adults: A Cross-Sectional Study, Lee Smith, Sarah E. Jackson, Shahina Pardhan, Guillermo Felipe López-Sánchez, Liang Hu, Chao Cao, Davy Vancampfort, Ai Koyanagi, Brendon Stubbs, Joseph Firth, Lin Yang

Open Access Publications

No abstract provided.


Effect Of Native And Acetylated Dietary Resistant Starches On Intestinal Fermentative Capacity Of Normal And Stunted Children In Southern India, Ramadass Balamurugan, Srinivasan Pugazhendhi, Gowri M Balachander, Tamilselvan Dharmalingam, Elissa K Mortimer, Geetha L Gopalsamy, Richard J Woodman, Rosie Meng, David H Alpers, Mark Manary, Henry J Binder, Ian L Brown, Graeme P Young, Balakrishnan S Ramakrishna Jan 2019

Effect Of Native And Acetylated Dietary Resistant Starches On Intestinal Fermentative Capacity Of Normal And Stunted Children In Southern India, Ramadass Balamurugan, Srinivasan Pugazhendhi, Gowri M Balachander, Tamilselvan Dharmalingam, Elissa K Mortimer, Geetha L Gopalsamy, Richard J Woodman, Rosie Meng, David H Alpers, Mark Manary, Henry J Binder, Ian L Brown, Graeme P Young, Balakrishnan S Ramakrishna

Open Access Publications

The health benefits of dietary amylase resistant starch (RS) arise from intestinal microbial fermentation and generation of short chain fatty acids (SCFA). We compared the intestinal fermentative capability of stunted and nonstunted ('healthy') children in southern India using two types of RS: high amylose maize starch (HAMS) and acetylated HAMS (HAMSA). Twenty children (10 stunted and 10 healthy) aged 2 to 5 years were fed biscuits containing HAMS (10 g/day) for two weeks followed by a 2-week washout and then HAMSA biscuits (10 g/day) for 2 weeks. Fecal samples were collected at 3-4 day intervals and pH and SCFA analyzed. …


Associations Of Autozygosity With A Broad Range Of Human Phenotypes, David W. Clark, Lihua Wang, Mary Feitosa, Dabeeru C. Rao, Et Al. Jan 2019

Associations Of Autozygosity With A Broad Range Of Human Phenotypes, David W. Clark, Lihua Wang, Mary Feitosa, Dabeeru C. Rao, Et Al.

Open Access Publications

No abstract provided.


Contribution And Interaction Of Shiga Toxin Genes To Escherichia Coli O157:H7 Virulence, Gillian A M Tarr, Taryn Stokowski, Smriti Shringi, Phillip I Tarr, Stephen B Freedman, Hanna N Oltean, Peter M Rabinowitz, Linda Chui Jan 2019

Contribution And Interaction Of Shiga Toxin Genes To Escherichia Coli O157:H7 Virulence, Gillian A M Tarr, Taryn Stokowski, Smriti Shringi, Phillip I Tarr, Stephen B Freedman, Hanna N Oltean, Peter M Rabinowitz, Linda Chui

Open Access Publications

No abstract provided.


Metabolically Healthy Obesity: Facts And Fantasies, Gordon I Smith, Bettina Mittendorfer, Samuel Klein Jan 2019

Metabolically Healthy Obesity: Facts And Fantasies, Gordon I Smith, Bettina Mittendorfer, Samuel Klein

Open Access Publications

Although obesity is typically associated with metabolic dysfunction and cardiometabolic diseases, some people with obesity are protected from many of the adverse metabolic effects of excess body fat and are considered "metabolically healthy." However, there is no universally accepted definition of metabolically healthy obesity (MHO). Most studies define MHO as having either 0, 1, or 2 metabolic syndrome components, whereas many others define MHO using the homeostasis model assessment of insulin resistance (HOMA-IR). Therefore, numerous people reported as having MHO are not metabolically healthy, but simply have fewer metabolic abnormalities than those with metabolically unhealthy obesity (MUO). Nonetheless, a small …


Regulation Of Lipophagy In Nafld By Cellular Metabolism And Cd36, Dmitri Samovski, Nada A. Abumrad Jan 2019

Regulation Of Lipophagy In Nafld By Cellular Metabolism And Cd36, Dmitri Samovski, Nada A. Abumrad

Open Access Publications

No abstract provided.


Hepatic Monoacylglycerol Acyltransferase 1 Is Induced By Prolonged Food Deprivation To Modulate The Hepatic Fasting Response, Andrew J. Lutkewitte, Kyle S. Mccommis, George G. Schweitzer, Kari T. Chambers, Mark J. Graham, Lingjue Wang, Gary J. Patti, Angela M. Hall, Brian N. Finck Jan 2019

Hepatic Monoacylglycerol Acyltransferase 1 Is Induced By Prolonged Food Deprivation To Modulate The Hepatic Fasting Response, Andrew J. Lutkewitte, Kyle S. Mccommis, George G. Schweitzer, Kari T. Chambers, Mark J. Graham, Lingjue Wang, Gary J. Patti, Angela M. Hall, Brian N. Finck

Open Access Publications

No abstract provided.


Visual Field Loss In Patients With Diabetes In The Absence Of Clinically-Detectable Vascular Retinopathy In A Nationally Representative Survey, Yicheng K. Bao, Yan Yan, Mae Gordon, Janet B. Mcgill, Michael Kass, Rithwick Rajagopal Jan 2019

Visual Field Loss In Patients With Diabetes In The Absence Of Clinically-Detectable Vascular Retinopathy In A Nationally Representative Survey, Yicheng K. Bao, Yan Yan, Mae Gordon, Janet B. Mcgill, Michael Kass, Rithwick Rajagopal

Open Access Publications

No abstract provided.


Stunting Is Preceded By Intestinal Mucosal Damage And Microbiome Changes And Is Associated With Systemic Inflammation In A Cohort Of Peruvian Infants, Mara Zambruni, Theresa J Ochoa, Anoma Somasunderam, Miguel M Cabada, Maria L Morales, Makedonka Mitreva, Bruce A Rosa, Gonzalo J Acosta, Natalia I Vigo, Maribel Riveros, Sara Arango, David Durand, Maitreyee N Berends, Peter Melby, Netanya S Utay Jan 2019

Stunting Is Preceded By Intestinal Mucosal Damage And Microbiome Changes And Is Associated With Systemic Inflammation In A Cohort Of Peruvian Infants, Mara Zambruni, Theresa J Ochoa, Anoma Somasunderam, Miguel M Cabada, Maria L Morales, Makedonka Mitreva, Bruce A Rosa, Gonzalo J Acosta, Natalia I Vigo, Maribel Riveros, Sara Arango, David Durand, Maitreyee N Berends, Peter Melby, Netanya S Utay

Open Access Publications

Stunting, defined as height-for-age


Advanced Glycation End Products Are Elevated In Estrogen Receptor-Positive Breast Cancer Patients, Alter Response To Therapy, And Can Be Targeted By Lifestyle Intervention, Katherine R. Walter, Lindsay L. Peterson, Et Al Jan 2019

Advanced Glycation End Products Are Elevated In Estrogen Receptor-Positive Breast Cancer Patients, Alter Response To Therapy, And Can Be Targeted By Lifestyle Intervention, Katherine R. Walter, Lindsay L. Peterson, Et Al

Open Access Publications

No abstract provided.


Building A Culture Of Health And Well-Being At Merck, Cathryn E. Gunther, Virginia Peddicord, Joseph Kozlowski, Yi Li, Danielle Menture, Raymond Fabius, Sharon Glave Frazee, Peter J. Nigro Jan 2019

Building A Culture Of Health And Well-Being At Merck, Cathryn E. Gunther, Virginia Peddicord, Joseph Kozlowski, Yi Li, Danielle Menture, Raymond Fabius, Sharon Glave Frazee, Peter J. Nigro

Open Access Publications

No abstract provided.


Prevalence And Impact Of Hepatitis E Virus Infection Among Persons With Chronic Hepatitis B Living In The Us And Canada, David R. Mcgivern, Hsing-Hua S. Lin, Junyao Wang, Tiffany Benzine, Henry L.A Janssen, Mandana Khalili, Mauricio Lisker-Melman, Robert J. Fontana, Steven H. Belle, Michael W. Fried Jan 2019

Prevalence And Impact Of Hepatitis E Virus Infection Among Persons With Chronic Hepatitis B Living In The Us And Canada, David R. Mcgivern, Hsing-Hua S. Lin, Junyao Wang, Tiffany Benzine, Henry L.A Janssen, Mandana Khalili, Mauricio Lisker-Melman, Robert J. Fontana, Steven H. Belle, Michael W. Fried

Open Access Publications

No abstract provided.


The Role Of Fecal Microbiota Transplantation In Reducing Intestinal Colonization With Antibiotic-Resistant Organisms: The Current Landscape And Future Directions, Michael H. Woodworth, Mary K. Hayden, Vincent B. Young, Jennie H. Kwon Jan 2019

The Role Of Fecal Microbiota Transplantation In Reducing Intestinal Colonization With Antibiotic-Resistant Organisms: The Current Landscape And Future Directions, Michael H. Woodworth, Mary K. Hayden, Vincent B. Young, Jennie H. Kwon

Open Access Publications

No abstract provided.


Obesity Alters The Muscle Protein Synthetic Response To Nutrition And Exercise, Joseph W Beals, Nicholas A Burd, Daniel R Moore, Stephan Van Vliet Jan 2019

Obesity Alters The Muscle Protein Synthetic Response To Nutrition And Exercise, Joseph W Beals, Nicholas A Burd, Daniel R Moore, Stephan Van Vliet

Open Access Publications

Improving the health of skeletal muscle is an important component of obesity treatment. Apart from allowing for physical activity, skeletal muscle tissue is fundamental for the regulation of postprandial macronutrient metabolism, a time period that represents when metabolic derangements are most often observed in adults with obesity. In order for skeletal muscle to retain its capacity for physical activity and macronutrient metabolism, its protein quantity and composition must be maintained through the efficient degradation and resynthesis for proper tissue homeostasis. Life-style behaviors such as increasing physical activity and higher protein diets are front-line treatment strategies to enhance muscle protein remodeling …


Study Of Environmental Enteropathy And Malnutrition (Seem) In Pakistan: Protocols For Biopsy Based Biomarker Discovery And Validation, Najeeha T. Iqbal, Ta-Chiang Liu, Michael J. Barratt, Vanderlene L. Kung, Jeffrey I. Gordon, Et Al Jan 2019

Study Of Environmental Enteropathy And Malnutrition (Seem) In Pakistan: Protocols For Biopsy Based Biomarker Discovery And Validation, Najeeha T. Iqbal, Ta-Chiang Liu, Michael J. Barratt, Vanderlene L. Kung, Jeffrey I. Gordon, Et Al

Open Access Publications

No abstract provided.


A Randomized Phase Ii Trial Of Nab‐Paclitaxel And Gemcitabine With Tarextumab Or Placebo In Patients With Untreated Metastatic Pancreatic Cancer, Zishuo Ian Hu, Andrea Wang-Gillam, Et Al Jan 2019

A Randomized Phase Ii Trial Of Nab‐Paclitaxel And Gemcitabine With Tarextumab Or Placebo In Patients With Untreated Metastatic Pancreatic Cancer, Zishuo Ian Hu, Andrea Wang-Gillam, Et Al

Open Access Publications

No abstract provided.


Type-2-Diabetes Alters Csf But Not Plasma Metabolomic And Ad Risk Profiles In Vervet Monkeys, Kylie Kavanagh, Stephen M. Day, Morgan C. Pait, William R. Mortiz, Christopher B. Newgard, Olga Ilkayeva, Donald A. Mcclain, Shannon L. Macauley Jan 2019

Type-2-Diabetes Alters Csf But Not Plasma Metabolomic And Ad Risk Profiles In Vervet Monkeys, Kylie Kavanagh, Stephen M. Day, Morgan C. Pait, William R. Mortiz, Christopher B. Newgard, Olga Ilkayeva, Donald A. Mcclain, Shannon L. Macauley

Open Access Publications

No abstract provided.


Oral Selinexor–Dexamethasone For Triple-Class Refractory Multiple Myeloma, Ravi Vij, Et Al. Jan 2019

Oral Selinexor–Dexamethasone For Triple-Class Refractory Multiple Myeloma, Ravi Vij, Et Al.

Open Access Publications

No abstract provided.