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Articles 3451 - 3480 of 4253
Full-Text Articles in Entire DC Network
Haploinsufficiency Of Human Apoe Reduces Amyloid Deposition In A Mouse Model Of Amyloid-Β Amyloidosis, Jungsu Kim, Hong Jiang, Seonha Park, Adam E.M. Eltorai, Floy R. Stewart, Hyejin Yoon, Jacob M. Basak, Mary Beth Finn, David M. Holtzman
Haploinsufficiency Of Human Apoe Reduces Amyloid Deposition In A Mouse Model Of Amyloid-Β Amyloidosis, Jungsu Kim, Hong Jiang, Seonha Park, Adam E.M. Eltorai, Floy R. Stewart, Hyejin Yoon, Jacob M. Basak, Mary Beth Finn, David M. Holtzman
Open Access Publications
No abstract provided.
Host Type I Ifn Signals Are Required For Antitumor Cd8+ T Cell Responses Through Cd8Α+ Dendritic Cells, Mercedes B. Fuertes, Aalok K. Kacha, Justin Kline, Seng-Ryong Woo, David M. Kranz, Kenneth M. Murphy, Thomas F. Gajewski
Host Type I Ifn Signals Are Required For Antitumor Cd8+ T Cell Responses Through Cd8Α+ Dendritic Cells, Mercedes B. Fuertes, Aalok K. Kacha, Justin Kline, Seng-Ryong Woo, David M. Kranz, Kenneth M. Murphy, Thomas F. Gajewski
Open Access Publications
No abstract provided.
A Nine Amino Acid Domain Is Essential For Mutant Prion Protein Toxicity, Laura Westergard, Jessie A. Turnbaugh, David A. Harris
A Nine Amino Acid Domain Is Essential For Mutant Prion Protein Toxicity, Laura Westergard, Jessie A. Turnbaugh, David A. Harris
Open Access Publications
No abstract provided.
Multisensory Calibration Is Independent Of Cue Reliability, Adam Zaidel, Amanda H. Turner, Dora E. Angelaki
Multisensory Calibration Is Independent Of Cue Reliability, Adam Zaidel, Amanda H. Turner, Dora E. Angelaki
Open Access Publications
No abstract provided.
Short-Term Plasticity Optimizes Synaptic Information Transmission, Ziv Rotman, Pan-Yue Deng, Vitaly A. Klyachko
Short-Term Plasticity Optimizes Synaptic Information Transmission, Ziv Rotman, Pan-Yue Deng, Vitaly A. Klyachko
Open Access Publications
No abstract provided.
Stathmin Is Required For Stability Of The Drosophila Neuromuscular Junction, Ethan R. Graf, Heather M. Heerssen, Christina M. Wright, Graeme W. Davis, Aaron Diantonio
Stathmin Is Required For Stability Of The Drosophila Neuromuscular Junction, Ethan R. Graf, Heather M. Heerssen, Christina M. Wright, Graeme W. Davis, Aaron Diantonio
Open Access Publications
No abstract provided.
Highwire Regulates Guidance Of Sister Axons In The Drosophila Mushroom Body, Jung Eun Shin, Aaron Diantonio
Highwire Regulates Guidance Of Sister Axons In The Drosophila Mushroom Body, Jung Eun Shin, Aaron Diantonio
Open Access Publications
No abstract provided.
Behavioral State Modulates The Activity Of Brainstem Sensorimotor Neurons, Kimberly L. Mcarthur, J. David Dickman
Behavioral State Modulates The Activity Of Brainstem Sensorimotor Neurons, Kimberly L. Mcarthur, J. David Dickman
Open Access Publications
No abstract provided.
The Role Of Attenuated Astrocyte Activation In Infantile Neuronal Ceroid Lipofuscinosis, Shannon L. Macauley, Milos Pekny, Mark S. Sands
The Role Of Attenuated Astrocyte Activation In Infantile Neuronal Ceroid Lipofuscinosis, Shannon L. Macauley, Milos Pekny, Mark S. Sands
Open Access Publications
No abstract provided.
Activator Protein 1 (Ap-1) Contributes To Epcam-Dependent Breast Cancer Invasion, Narenda V. Sankpal, John D. Mayfield, Mike W. Willman, Timothy P. Fleming, William E. Gillanders
Activator Protein 1 (Ap-1) Contributes To Epcam-Dependent Breast Cancer Invasion, Narenda V. Sankpal, John D. Mayfield, Mike W. Willman, Timothy P. Fleming, William E. Gillanders
Open Access Publications
No abstract provided.
The Impact Of Vancomycin Susceptibility On Treatment Outcomes Among Patients With Methicillin Resistant Staphylococcus Aureus Bacteremia, Hitoshi Honda, Christopher D. Doern, Wm Michael Dunne Jr, David K. Warren
The Impact Of Vancomycin Susceptibility On Treatment Outcomes Among Patients With Methicillin Resistant Staphylococcus Aureus Bacteremia, Hitoshi Honda, Christopher D. Doern, Wm Michael Dunne Jr, David K. Warren
Open Access Publications
No abstract provided.
Effects Of Human Immunodeficiency Virus And Metabolic Complications On Myocardial Nutrient Metabolism, Blood Flow, And Oxygen Consumption: A Cross-Sectional Analysis, W Todd Cade, Dominic N. Reeds, E Turner Overton, Pilar Herrero, Alan D. Waggoner, Victor G. Davila-Roman, Sherry Lassa-Claxton, Robert J. Gropler, Pablo F. Soto, Melissa J. Krauss, Kevin E. Yarasheski, Linda R. Peterson
Effects Of Human Immunodeficiency Virus And Metabolic Complications On Myocardial Nutrient Metabolism, Blood Flow, And Oxygen Consumption: A Cross-Sectional Analysis, W Todd Cade, Dominic N. Reeds, E Turner Overton, Pilar Herrero, Alan D. Waggoner, Victor G. Davila-Roman, Sherry Lassa-Claxton, Robert J. Gropler, Pablo F. Soto, Melissa J. Krauss, Kevin E. Yarasheski, Linda R. Peterson
Open Access Publications
No abstract provided.
Gender-Associated Genes In Filarial Nematodes Are Important For Reproduction And Potential Intervention Targets, Ben-Wen Li, Amy C. Rush, Dao-Jun Jiang, Makedonka Mitreva, Sahar Abubucker, Gary J. Weil
Gender-Associated Genes In Filarial Nematodes Are Important For Reproduction And Potential Intervention Targets, Ben-Wen Li, Amy C. Rush, Dao-Jun Jiang, Makedonka Mitreva, Sahar Abubucker, Gary J. Weil
Open Access Publications
No abstract provided.
Toward An Integrated Approach To Perception And Action: Conference Report And Future Directions, Goren Gordon, David M. Kaplan, Benjamin Lankow, Daniel Ying-Jeh Little, Jason Sherwin, Benjamin A. Suter, Lore Thaler
Toward An Integrated Approach To Perception And Action: Conference Report And Future Directions, Goren Gordon, David M. Kaplan, Benjamin Lankow, Daniel Ying-Jeh Little, Jason Sherwin, Benjamin A. Suter, Lore Thaler
Open Access Publications
No abstract provided.
Functional Metagenomic Investigations Of The Human Intestinal Microbiota, Aimee M. Moore, Christian Munck, Morten O.A Sommer, Gautam Dantas
Functional Metagenomic Investigations Of The Human Intestinal Microbiota, Aimee M. Moore, Christian Munck, Morten O.A Sommer, Gautam Dantas
Open Access Publications
No abstract provided.
Positive Affect Versus Reward: Emotional And Motivational Influences On Cognitive Control, Kimberly S. Chiew, Todd S. Braver
Positive Affect Versus Reward: Emotional And Motivational Influences On Cognitive Control, Kimberly S. Chiew, Todd S. Braver
Open Access Publications
No abstract provided.
Bioluminescence Imaging Captures The Expression And Dynamics Of Endogenous P21 Promoter Activity In Living Mice And Intact Cells, Kelsey L. Tinkum, Luciano Marpegan, Lynn S. White, Jinwu Sun, Erik D. Herzog, David Piwnica-Worms, Helen Piwnica-Worms
Bioluminescence Imaging Captures The Expression And Dynamics Of Endogenous P21 Promoter Activity In Living Mice And Intact Cells, Kelsey L. Tinkum, Luciano Marpegan, Lynn S. White, Jinwu Sun, Erik D. Herzog, David Piwnica-Worms, Helen Piwnica-Worms
Open Access Publications
No abstract provided.
Oxytocin Receptor (Oxtr) Polymorphisms And Attachment In Human Infants, Frances S. Chen, Maria E. Barth, Stephen L. Johnson, Ian H. Gotlib, Susan C. Johnson
Oxytocin Receptor (Oxtr) Polymorphisms And Attachment In Human Infants, Frances S. Chen, Maria E. Barth, Stephen L. Johnson, Ian H. Gotlib, Susan C. Johnson
Open Access Publications
No abstract provided.
Gs-8374, A Novel Hiv Protease Inhibitor, Does Not Alter Glucose Homeostasis In Cultured Adipocytes Or In A Healthy-Rodent Model System, Paul W. Hruz, Qingyun Yan, Luong Tsai, Joseph Koster, Lianhong Xu, Tomas Cihlar, Christian Callebaut
Gs-8374, A Novel Hiv Protease Inhibitor, Does Not Alter Glucose Homeostasis In Cultured Adipocytes Or In A Healthy-Rodent Model System, Paul W. Hruz, Qingyun Yan, Luong Tsai, Joseph Koster, Lianhong Xu, Tomas Cihlar, Christian Callebaut
Open Access Publications
No abstract provided.
The Diverse Functions Of Short-Term Plasticity Components In Synaptic Computations, Pan-Yue Deng, Vitaly A. Klyachko
The Diverse Functions Of Short-Term Plasticity Components In Synaptic Computations, Pan-Yue Deng, Vitaly A. Klyachko
Open Access Publications
No abstract provided.
Organogenesis Of The Kidney Glomerulus: Focus On The Glomerular Basement Membrane, Jeffrey H. Miner
Organogenesis Of The Kidney Glomerulus: Focus On The Glomerular Basement Membrane, Jeffrey H. Miner
Open Access Publications
No abstract provided.
Immune Activation And Suppression By Group B Streptococcus In A Murine Model Of Urinary Tract Infection, Kimberly A. Kline, Drew J. Schwartz, Warren G. Lewis, Scott J. Hultgren, Amanda L. Lewis
Immune Activation And Suppression By Group B Streptococcus In A Murine Model Of Urinary Tract Infection, Kimberly A. Kline, Drew J. Schwartz, Warren G. Lewis, Scott J. Hultgren, Amanda L. Lewis
Open Access Publications
No abstract provided.
Population Dynamics And Niche Distribution Of Uropathogenic Escherichia Coli During Acute And Chronic Urinary Tract Infection, Drew J. Schwartz, Swaine L. Chen, Scott J. Hultgren, Patrick C. Seed
Population Dynamics And Niche Distribution Of Uropathogenic Escherichia Coli During Acute And Chronic Urinary Tract Infection, Drew J. Schwartz, Swaine L. Chen, Scott J. Hultgren, Patrick C. Seed
Open Access Publications
No abstract provided.
West Nile Virus Infection In Killer Whale, Texas, Usa, 2007, Judy St. Leger, Guang Wu, Mark Anderson, Les Dalton, Erika Nilson, David Wang
West Nile Virus Infection In Killer Whale, Texas, Usa, 2007, Judy St. Leger, Guang Wu, Mark Anderson, Les Dalton, Erika Nilson, David Wang
Open Access Publications
No abstract provided.
Golgi Cells Operate As State-Specific Temporal Filters At The Input Stage Of The Cerebellar Cortex, Shane A. Heine, Stephen M. Highstein, Pablo M. Blazquez
Golgi Cells Operate As State-Specific Temporal Filters At The Input Stage Of The Cerebellar Cortex, Shane A. Heine, Stephen M. Highstein, Pablo M. Blazquez
Open Access Publications
Cerebellar processing of incoming information begins at the synapse between mossy fibers and granule cells, a synapse that is strongly controlled through Golgi cell inhibition. Thus, Golgi cells are uniquely positioned to control the flow of information into the cerebellar cortex and understanding their responses during behavior is essential to understanding cerebellar function. Here we show, for the first time, that Golgi cells express a unique oculomotor-related signal that can be used to provide state- and time-specific filtering of granule cell activity. We used newly established criteria to identify the unique electrophysiological signature of Golgi cells and recorded these neurons …
Midazolam Inhibits Hippocampal Long-Term Potentiation And Learning Through Dual Central And Peripheral Benzodiazepine Receptor Activation And Neurosteroidogenesis, Kazuhiro Tokuda, Kazuko A. O'Dell, Yukitoshi Izumi, Charles F. Zorumski
Midazolam Inhibits Hippocampal Long-Term Potentiation And Learning Through Dual Central And Peripheral Benzodiazepine Receptor Activation And Neurosteroidogenesis, Kazuhiro Tokuda, Kazuko A. O'Dell, Yukitoshi Izumi, Charles F. Zorumski
Open Access Publications
Benzodiazepines (BDZs) enhance GABA(A) receptor inhibition by direct actions on central BDZ receptors (CBRs). Although some BDZs also bind mitochondrial receptors [translocator protein (18 kDa) (TSPO)] and promote the synthesis of GABA-enhancing neurosteroids, the role of neurosteroids in the clinical effects of BDZs is unknown. In rat hippocampal slices, we compared midazolam, an anesthetic BDZ, with clonazepam, an anticonvulsant/anxiolytic BDZ that activates CBRs selectively. Midazolam, but not clonazepam, increased neurosteroid levels in CA1 pyramidal neurons without changing TSPO immunostaining. Midazolam, but not clonazepam, also augmented a form of spike inhibition after stimulation adjacent to the pyramidal cell layer and inhibited …
Membrane Anchoring Subunits Specify Selective Regulation Of Rgs9·Gbeta5 Gap Complex In Photoreceptor Neurons, Yan Cao, Alexander V. Kolesnikov, Ikuo Masuho, Vladimir J. Kefalov, Kirill A. Martemyanov
Membrane Anchoring Subunits Specify Selective Regulation Of Rgs9·Gbeta5 Gap Complex In Photoreceptor Neurons, Yan Cao, Alexander V. Kolesnikov, Ikuo Masuho, Vladimir J. Kefalov, Kirill A. Martemyanov
Open Access Publications
The RGS9·Gβ5 complex is the key regulator of neuronal G-protein signaling and shows remarkable selectivity of subunit composition. In retinal photoreceptors, RGS9·Gβ5 is bound to the membrane anchor R9AP and the complex regulates visual signaling. In the basal ganglia neurons, RGS9·Gβ5 is instead associated with a homologous protein, R7BP, and regulates reward circuit. Switching this selective subunit composition of the complex in rod photoreceptors allowed us to study the molecular underpinning of signaling specificity in diverse G-protein pathways. We have found that both membrane anchoring subunits play a conserved role in regulating protein levels of RGS9·Gβ5 and enhancing the ability …
Protein Turnover Of The Wallenda/Dlk Kinase Regulates A Retrograde Response To Axonal Injury, Xin Xiong, Xin Wang, Ronny Ewanek, Pavan Bhat, Aaron Diantonio, Catherine A. Collins
Protein Turnover Of The Wallenda/Dlk Kinase Regulates A Retrograde Response To Axonal Injury, Xin Xiong, Xin Wang, Ronny Ewanek, Pavan Bhat, Aaron Diantonio, Catherine A. Collins
Open Access Publications
No abstract provided.
Age-Related Deterioration Of Rod Vision In Mice, Alexander V. Kolesnikov, Jie Fan, Rosalie K. Crouch, Vladimir J. Kefalov
Age-Related Deterioration Of Rod Vision In Mice, Alexander V. Kolesnikov, Jie Fan, Rosalie K. Crouch, Vladimir J. Kefalov
Open Access Publications
Even in healthy individuals, aging leads to deterioration in visual acuity, contrast sensitivity, visual field, and dark adaptation. Little is known about the neural mechanisms that drive the age-related changes of the retina and, more specifically, photoreceptors. According to one hypothesis, the age-related deterioration in rod function is due to the limited availability of 11-cis-retinal for rod pigment formation. To determine how aging affects rod photoreceptors and to test the retinoid-deficiency hypothesis, we compared the morphological and functional properties of rods of adult and aged B6D2F1/J mice. We found that the number of rods and the length of their outer …
What's New In Spine Surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, Jeffrey C. Wang
What's New In Spine Surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, Jeffrey C. Wang
Open Access Publications
No abstract provided.