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Articles 3481 - 3510 of 4253
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Molecular Dissection Of I(A) In Cortical Pyramidal Neurons Reveals Three Distinct Components Encoded By Kv4.2, Kv4.3, And Kv1.4 Alpha-Subunits, Aaron J. Norris, Jeanne M. Nerbonne
Molecular Dissection Of I(A) In Cortical Pyramidal Neurons Reveals Three Distinct Components Encoded By Kv4.2, Kv4.3, And Kv1.4 Alpha-Subunits, Aaron J. Norris, Jeanne M. Nerbonne
Open Access Publications
The rapidly activating and inactivating voltage-gated K(+) (Kv) current, I(A), is broadly expressed in neurons and is a key regulator of action potential repolarization, repetitive firing, backpropagation (into dendrites) of action potentials, and responses to synaptic inputs. Interestingly, results from previous studies on a number of neuronal cell types, including hippocampal, cortical, and spinal neurons, suggest that macroscopic I(A) is composed of multiple components and that each component is likely encoded by distinct Kv channel alpha-subunits. The goals of the experiments presented here were to test this hypothesis and to determine the molecular identities of the Kv channel alpha-subunits that …
Relationship Of Tear Size And Location To Fatty Degeneration Of The Rotator Cuff, H. Mike Kim, Nirvikar Dahiya, Sharlene A. Teefey, Jay D. Keener, Leesa M. Galatz, Ken Yamaguchi
Relationship Of Tear Size And Location To Fatty Degeneration Of The Rotator Cuff, H. Mike Kim, Nirvikar Dahiya, Sharlene A. Teefey, Jay D. Keener, Leesa M. Galatz, Ken Yamaguchi
Open Access Publications
No abstract provided.
The Novel Endosomal Membrane Protein Ema Interacts With The Class C Vps-Hops Complex To Promote Endosomal Maturation, Sungsu Kim, Yogesh P. Wairkar, Richard W. Daniels, Aaron Diantonio
The Novel Endosomal Membrane Protein Ema Interacts With The Class C Vps-Hops Complex To Promote Endosomal Maturation, Sungsu Kim, Yogesh P. Wairkar, Richard W. Daniels, Aaron Diantonio
Open Access Publications
Endosomal maturation is critical for accurate and efficient cargo transport through endosomal compartments. Here we identify a mutation of the novel Drosophila gene, ema (endosomal maturation defective) in a screen for abnormal synaptic overgrowth and defective protein trafficking. Ema is an endosomal membrane protein required for trafficking of fluid-phase and receptor-mediated endocytic cargos. In the ema mutant, enlarged endosomal compartments accumulate as endosomal maturation fails, with early and late endosomes unable to progress into mature degradative late endosomes and lysosomes. Defective endosomal down-regulation of BMP signaling is responsible for the abnormal synaptic overgrowth. Ema binds to and genetically interacts with …
Soluble Amyloid-Β, Effect On Cerebral Arteriolar Regulation And Vascular Cells, Hans H. Dietrich, Chuanxi Xiang, Byung H. Han, Gregory J. Zipfel, David M. Holtzman
Soluble Amyloid-Β, Effect On Cerebral Arteriolar Regulation And Vascular Cells, Hans H. Dietrich, Chuanxi Xiang, Byung H. Han, Gregory J. Zipfel, David M. Holtzman
Open Access Publications
No abstract provided.
Coordinated Progression Through Two Subtranscriptomes Underlies The Tachyzoite Cycle Of Toxoplasma Gondii, Michael S. Behnke, John C. Wootton, Margaret M. Lehmann, Josh B. Radke, Olivier Lucas, Julie Nawas, L. David Sibley, Michael W. White
Coordinated Progression Through Two Subtranscriptomes Underlies The Tachyzoite Cycle Of Toxoplasma Gondii, Michael S. Behnke, John C. Wootton, Margaret M. Lehmann, Josh B. Radke, Olivier Lucas, Julie Nawas, L. David Sibley, Michael W. White
Open Access Publications
No abstract provided.
A Method For Determining Cell Number In The Undisturbed Epithelium Of The Mouse Lens, Steven Bassnett, Yanrong Shi
A Method For Determining Cell Number In The Undisturbed Epithelium Of The Mouse Lens, Steven Bassnett, Yanrong Shi
Open Access Publications
No abstract provided.
Lipidomics Analysis Reveals Efficient Storage Of Hepatic Triacylglycerides Enriched In Unsaturated Fatty Acids After One Bout Of Exercise In Mice, Chunxiu Hu, Miriam Hoene, Xinjie Zhao, Hans U. Haring, Erwin Schleicher, Rainer Lehmann, Xianlin Han, Guowang Xu, Cora Weigert
Lipidomics Analysis Reveals Efficient Storage Of Hepatic Triacylglycerides Enriched In Unsaturated Fatty Acids After One Bout Of Exercise In Mice, Chunxiu Hu, Miriam Hoene, Xinjie Zhao, Hans U. Haring, Erwin Schleicher, Rainer Lehmann, Xianlin Han, Guowang Xu, Cora Weigert
Open Access Publications
No abstract provided.
The Perilipin Homologue, Lipid Storage Droplet 2, Regulates Sleep Homeostasis And Prevents Learning Impairments Following Sleep Loss, Matthew S. Thimgan, Yasuko Suzuki, Laurent Seugnet, Laura Gottschalk, Paul J. Shaw
The Perilipin Homologue, Lipid Storage Droplet 2, Regulates Sleep Homeostasis And Prevents Learning Impairments Following Sleep Loss, Matthew S. Thimgan, Yasuko Suzuki, Laurent Seugnet, Laura Gottschalk, Paul J. Shaw
Open Access Publications
No abstract provided.
Mhc Class I–Deficient Natural Killer Cells Acquire A Licensed Phenotype After Transfer Into An Mhc Class I–Sufficient Environment, Julie M. Elliott, Joseph A. Wahle, Wayne M. Yokoyama
Mhc Class I–Deficient Natural Killer Cells Acquire A Licensed Phenotype After Transfer Into An Mhc Class I–Sufficient Environment, Julie M. Elliott, Joseph A. Wahle, Wayne M. Yokoyama
Open Access Publications
No abstract provided.
The Role Of Axonopathy In Parkinson's Disease, Karen L. O’Malley
The Role Of Axonopathy In Parkinson's Disease, Karen L. O’Malley
Open Access Publications
No abstract provided.
Comparison Of Amounts And Types Of Practice During Rehabilitation For Traumatic Brain Injury And Stroke, Teresa Jacobson Kimberley, Sharyl Samargia, Lisa G. Moore, Josefin K. Shakya, Catherine E. Lang
Comparison Of Amounts And Types Of Practice During Rehabilitation For Traumatic Brain Injury And Stroke, Teresa Jacobson Kimberley, Sharyl Samargia, Lisa G. Moore, Josefin K. Shakya, Catherine E. Lang
Open Access Publications
No abstract provided.
A Toolkit For Rapid Gene Mapping In The Nematode Caenorhabditis Briggsae, Daniel C. Koboldt, Julia Staisch, Bavithra Thillainathan, Karen Haines, Scott E. Baird, Helen M. Chamberlin, Eric S. Haag, Raymond D. Miller, Bhagwati P. Gupta
A Toolkit For Rapid Gene Mapping In The Nematode Caenorhabditis Briggsae, Daniel C. Koboldt, Julia Staisch, Bavithra Thillainathan, Karen Haines, Scott E. Baird, Helen M. Chamberlin, Eric S. Haag, Raymond D. Miller, Bhagwati P. Gupta
Open Access Publications
No abstract provided.
Parallel Input Channels To Mouse Primary Visual Cortex, Enquan Gao, Gregory C. Deangelis, Andreas Burkhalter
Parallel Input Channels To Mouse Primary Visual Cortex, Enquan Gao, Gregory C. Deangelis, Andreas Burkhalter
Open Access Publications
No abstract provided.
Direction Discrimination Thresholds Of Vestibular And Cerebellar Nuclei Neurons, Sheng Liu, Tatyana Yakusheva, Gregory C. Deangelis, Dora E. Angelaki
Direction Discrimination Thresholds Of Vestibular And Cerebellar Nuclei Neurons, Sheng Liu, Tatyana Yakusheva, Gregory C. Deangelis, Dora E. Angelaki
Open Access Publications
No abstract provided.
Loss Of Par-1a/Mark3/C-Tak1 Kinase Leads To Reduced Adiposity, Resistance To Hepatic Steatosis, And Defective Gluconeogenesis, Jochen K. Lennerz, Jonathan B. Hurov, Lynn S. White, Katherine T. Lewandowski, Julie L. Prior, G. James Planer, Robert W. Gereau Iv, David Piwnica-Worms, Robert E. Schmidt, Helen Piwnica-Worms
Loss Of Par-1a/Mark3/C-Tak1 Kinase Leads To Reduced Adiposity, Resistance To Hepatic Steatosis, And Defective Gluconeogenesis, Jochen K. Lennerz, Jonathan B. Hurov, Lynn S. White, Katherine T. Lewandowski, Julie L. Prior, G. James Planer, Robert W. Gereau Iv, David Piwnica-Worms, Robert E. Schmidt, Helen Piwnica-Worms
Open Access Publications
No abstract provided.
Cd46 Engagement On Human Cd4+ T Cells Produces T Regulatory Type 1-Like Regulation Of Antimycobacterial T Cell Responses, Steven M. Truscott, Getahun Abate, Jeffrey D. Price, Claudia Kemper, John P. Atkinson, Daniel F. Hoft
Cd46 Engagement On Human Cd4+ T Cells Produces T Regulatory Type 1-Like Regulation Of Antimycobacterial T Cell Responses, Steven M. Truscott, Getahun Abate, Jeffrey D. Price, Claudia Kemper, John P. Atkinson, Daniel F. Hoft
Open Access Publications
No abstract provided.
Characterization Of A Novel Murine Model Of Staphylococcus Saprophyticus Urinary Tract Infection Reveals Roles For Ssp And Sdri In Virulence, Kimberly A. Kline, Molly A. Ingersoll, Hailyn V. Nielsen, Turkan Sakinc, Michael G. Caparon, Scott J. Hultgren
Characterization Of A Novel Murine Model Of Staphylococcus Saprophyticus Urinary Tract Infection Reveals Roles For Ssp And Sdri In Virulence, Kimberly A. Kline, Molly A. Ingersoll, Hailyn V. Nielsen, Turkan Sakinc, Michael G. Caparon, Scott J. Hultgren
Open Access Publications
No abstract provided.
Thymoglobulin Induction Dosing Strategies In A Low-Risk Kidney Transplant Population: Three Or Four Days?, Karen L. Hardinger, Rafia S. Rasu, Rebecca Skelton, Brent W. Miller, Daniel C. Brennan
Thymoglobulin Induction Dosing Strategies In A Low-Risk Kidney Transplant Population: Three Or Four Days?, Karen L. Hardinger, Rafia S. Rasu, Rebecca Skelton, Brent W. Miller, Daniel C. Brennan
Open Access Publications
No abstract provided.
A Monoclonal Antibody Toolkit For C. Elegans, Gayla Hadwiger, Scott Dour, Swathi Arur, Paul Fox, Michael L. Nonet
A Monoclonal Antibody Toolkit For C. Elegans, Gayla Hadwiger, Scott Dour, Swathi Arur, Paul Fox, Michael L. Nonet
Open Access Publications
No abstract provided.
Nik Stabilization In Osteoclasts Results In Osteoporosis And Enhanced Inflammatory Osteolysis, Chang Yang, Kathleen Mccoy, Jennifer L. Davis, Marc Schmidt-Supprian, Yoshiteru Sasaki, Roberta Faccio, Deborah Veis Novack
Nik Stabilization In Osteoclasts Results In Osteoporosis And Enhanced Inflammatory Osteolysis, Chang Yang, Kathleen Mccoy, Jennifer L. Davis, Marc Schmidt-Supprian, Yoshiteru Sasaki, Roberta Faccio, Deborah Veis Novack
Open Access Publications
No abstract provided.
The Development Of Therapeutic Antibodies That Neutralize Homologous And Heterologous Genotypes Of Dengue Virus Type 1, Bimmi Shrestha, James D. Brien, Soila Sukupolvi-Petty, S. Kyle Austin, Melissa A. Edeling, Taekyung Kim, Katie M. O'Brien, Christopher A. Nelson, Syd Johnson, Daved H. Fremont, Michael S. Diamond
The Development Of Therapeutic Antibodies That Neutralize Homologous And Heterologous Genotypes Of Dengue Virus Type 1, Bimmi Shrestha, James D. Brien, Soila Sukupolvi-Petty, S. Kyle Austin, Melissa A. Edeling, Taekyung Kim, Katie M. O'Brien, Christopher A. Nelson, Syd Johnson, Daved H. Fremont, Michael S. Diamond
Open Access Publications
No abstract provided.
Rhomboid 4 (Rom4) Affects The Processing Of Surface Adhesins And Facilitates Host Cell Invasion By Toxoplasma Gondii, Jeffrey S. Buguliskis, Fabien Brossier, Joel Shuman, L. David Sibley
Rhomboid 4 (Rom4) Affects The Processing Of Surface Adhesins And Facilitates Host Cell Invasion By Toxoplasma Gondii, Jeffrey S. Buguliskis, Fabien Brossier, Joel Shuman, L. David Sibley
Open Access Publications
No abstract provided.
Phospholipase C Gamma 2 Is Critical For Development Of A Murine Model Of Inflammatory Arthritis By Affecting Actin Dynamics In Dendritic Cells, Viviana Cremasco, Elisa Benasciutti, Marina Cella, Marina Kisseleva, Monica Croke, Roberta Faccio
Phospholipase C Gamma 2 Is Critical For Development Of A Murine Model Of Inflammatory Arthritis By Affecting Actin Dynamics In Dendritic Cells, Viviana Cremasco, Elisa Benasciutti, Marina Cella, Marina Kisseleva, Monica Croke, Roberta Faccio
Open Access Publications
No abstract provided.
Synthesizing And Salvaging Nad+: Lessons Learned From Chlamydomonas Reinhardtii, Huawen Lin, Alan L. Kwan, Susan K. Dutcher
Synthesizing And Salvaging Nad+: Lessons Learned From Chlamydomonas Reinhardtii, Huawen Lin, Alan L. Kwan, Susan K. Dutcher
Open Access Publications
No abstract provided.
Enhanced Hepatic Apoa-I Secretion And Peripheral Efflux Of Cholesterol And Phospholipid In Cd36 Null Mice, Pin Yue, Zhouji Chen, Fatiha Nassir, Carlos Bernal-Mizrachi, Brian Finck, Salman Azhar, Nada A. Abumrad
Enhanced Hepatic Apoa-I Secretion And Peripheral Efflux Of Cholesterol And Phospholipid In Cd36 Null Mice, Pin Yue, Zhouji Chen, Fatiha Nassir, Carlos Bernal-Mizrachi, Brian Finck, Salman Azhar, Nada A. Abumrad
Open Access Publications
No abstract provided.
Phosphorylation Of Mouse Immunity-Related Gtpase (Irg) Resistance Proteins Is An Evasion Strategy For Virulent Toxoplasma Gondii, Tobias Steinfeldt, Stephanie Konen-Waisman, Lan Tong, Nikolaus Pawlowski, Tobias Lamkemeyer, L. David Sibley, Julia P. Hunn, Jonathan C. Howard
Phosphorylation Of Mouse Immunity-Related Gtpase (Irg) Resistance Proteins Is An Evasion Strategy For Virulent Toxoplasma Gondii, Tobias Steinfeldt, Stephanie Konen-Waisman, Lan Tong, Nikolaus Pawlowski, Tobias Lamkemeyer, L. David Sibley, Julia P. Hunn, Jonathan C. Howard
Open Access Publications
No abstract provided.
Dinitroaniline Activity In Toxoplasma Gondii Expressing Wild-Type Or Mutant Α-Tubulin, Christopher Ma, Johnson Tran, Frank Gu, Roxanna Ochoa, Catherine Li, David Sept, Naomi Morrissette
Dinitroaniline Activity In Toxoplasma Gondii Expressing Wild-Type Or Mutant Α-Tubulin, Christopher Ma, Johnson Tran, Frank Gu, Roxanna Ochoa, Catherine Li, David Sept, Naomi Morrissette
Open Access Publications
No abstract provided.
Empiric Combination Antibiotic Therapy Is Associated With Improved Outcome Against Sepsis Due To Gram-Negative Bacteria: A Retrospective Analysis, Scott T. Micek, Emily C. Welch, Junaid Khan, Mubashir Pervez, Joshua A. Doherty, Richard M. Reichley, Marin H. Kollef
Empiric Combination Antibiotic Therapy Is Associated With Improved Outcome Against Sepsis Due To Gram-Negative Bacteria: A Retrospective Analysis, Scott T. Micek, Emily C. Welch, Junaid Khan, Mubashir Pervez, Joshua A. Doherty, Richard M. Reichley, Marin H. Kollef
Open Access Publications
No abstract provided.
Mcl1 Haploinsufficiency Protects Mice From Myc-Induced Acute Myeloid Leukemia, Zhifu Xiang, Hui Luo, Jacqueline E. Payton, Jennifer Cain, Timothy J. Ley, Joseph T. Opferman, Michael H. Tomasson
Mcl1 Haploinsufficiency Protects Mice From Myc-Induced Acute Myeloid Leukemia, Zhifu Xiang, Hui Luo, Jacqueline E. Payton, Jennifer Cain, Timothy J. Ley, Joseph T. Opferman, Michael H. Tomasson
Open Access Publications
No abstract provided.
Effect Of Alternative Temozolomide Schedules On Glioblastoma O 6-Methylguanine-Dna Methyltransferase Activity And Survival, Clifford G. Robinson, Juan M. Palomo, Gazanfar Rahmathulla, Mary V. Mcgraw, Jon R. Donze, Lili Liu, Michael A. Vogelbaum
Effect Of Alternative Temozolomide Schedules On Glioblastoma O 6-Methylguanine-Dna Methyltransferase Activity And Survival, Clifford G. Robinson, Juan M. Palomo, Gazanfar Rahmathulla, Mary V. Mcgraw, Jon R. Donze, Lili Liu, Michael A. Vogelbaum
Open Access Publications
No abstract provided.