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Detection Of Rapalog-Mediated Therapeutic Response In Renal Cancer Xenografts Using (64)Cu-Bevacizumab Immunopet, Albert J. Chang, Rebecca Sohn, Zhi Hong Lu, Jeffrey M. Arbeit, Suzanne E. Lapi Jan 2013

Detection Of Rapalog-Mediated Therapeutic Response In Renal Cancer Xenografts Using (64)Cu-Bevacizumab Immunopet, Albert J. Chang, Rebecca Sohn, Zhi Hong Lu, Jeffrey M. Arbeit, Suzanne E. Lapi

Open Access Publications

No abstract provided.


Prolonged Systemic Inflammation Persistently Modifies Synaptic Plasticity In The Hippocampus: Modulation By The Stress Hormones, Nicola Maggio, Efrat Shavit-Stein, Amir Dori, Ilan Blatt, Joab Chapman Jan 2013

Prolonged Systemic Inflammation Persistently Modifies Synaptic Plasticity In The Hippocampus: Modulation By The Stress Hormones, Nicola Maggio, Efrat Shavit-Stein, Amir Dori, Ilan Blatt, Joab Chapman

Open Access Publications

No abstract provided.


Infection Of Myofibers Contributes To Increased Pathogenicity During Infection With An Epidemic Strain Of Chikungunya Virus, Anjali Rohatgi, Joseph C. Corbo, Kristen Monte, Stephen Higgs, Dana L. Vanlandingham, Gabrielle Kardon, Deborah J. Lenschow Jan 2013

Infection Of Myofibers Contributes To Increased Pathogenicity During Infection With An Epidemic Strain Of Chikungunya Virus, Anjali Rohatgi, Joseph C. Corbo, Kristen Monte, Stephen Higgs, Dana L. Vanlandingham, Gabrielle Kardon, Deborah J. Lenschow

Open Access Publications

No abstract provided.


Autophagy Activity Contributes To Programmed Cell Death In Caenorhabditis Elegans, Haibin Wang, Qun Lu, Shiya Cheng, Xiaochen Wang, Hong Zhang Jan 2013

Autophagy Activity Contributes To Programmed Cell Death In Caenorhabditis Elegans, Haibin Wang, Qun Lu, Shiya Cheng, Xiaochen Wang, Hong Zhang

Open Access Publications

No abstract provided.


Retinoblastoma Protein Prevents Enteric Nervous System Defects And Intestinal Pseudo-Obstruction, Ming Fu, Solange Landreville, Olga A. Agapova, Luke A. Wiley, Michael Shoykhet, J. William Harbour, Robert O. Heuckeroth Jan 2013

Retinoblastoma Protein Prevents Enteric Nervous System Defects And Intestinal Pseudo-Obstruction, Ming Fu, Solange Landreville, Olga A. Agapova, Luke A. Wiley, Michael Shoykhet, J. William Harbour, Robert O. Heuckeroth

Open Access Publications

No abstract provided.


Hypotension Due To Kir6.1 Gain‐Of‐Function In Vascular Smooth Muscle, Anlong Li, Russell H. Knutsen, Haixia Zhang, Patrick Osei-Owusu, Alex Moreno-Dominguez, Theresa M. Harter, Keita Uchida, Maria S. Remedi, Hans H. Dietrich, Carlos Bernal-Mizrachi, Kendall J. Blumer, Robert P. Mecham, Joseph C. Koster, Colin G. Nichols Jan 2013

Hypotension Due To Kir6.1 Gain‐Of‐Function In Vascular Smooth Muscle, Anlong Li, Russell H. Knutsen, Haixia Zhang, Patrick Osei-Owusu, Alex Moreno-Dominguez, Theresa M. Harter, Keita Uchida, Maria S. Remedi, Hans H. Dietrich, Carlos Bernal-Mizrachi, Kendall J. Blumer, Robert P. Mecham, Joseph C. Koster, Colin G. Nichols

Open Access Publications

No abstract provided.


Detection Of Leishmania Rna Virus In Leishmania Parasites, Haroun Zangger, Catherine Ronet, Chantal Desponds, F. Matthew Kuhlmann, John Robinson, Mary-Anne Hartley, Florence Prevel, Patrik Castiglioni, Francine Pratlong, Patrick Bastien, Norbert Muller, Laurent Parmentier, Nancy Gore Saravia, Stephen M. Beverley, Nicolas Fasel Jan 2013

Detection Of Leishmania Rna Virus In Leishmania Parasites, Haroun Zangger, Catherine Ronet, Chantal Desponds, F. Matthew Kuhlmann, John Robinson, Mary-Anne Hartley, Florence Prevel, Patrik Castiglioni, Francine Pratlong, Patrick Bastien, Norbert Muller, Laurent Parmentier, Nancy Gore Saravia, Stephen M. Beverley, Nicolas Fasel

Open Access Publications

No abstract provided.


Genomic And Metabolic Disposition Of Non-Obese Type 2 Diabetic Rats To Increased Myocardial Fatty Acid Metabolism, Sriram Devanathan, Samuel T. Nemanich, Attila Kovacs, Nicole Fettig, Robert J. Gropler, Kooresh I. Shoghi Jan 2013

Genomic And Metabolic Disposition Of Non-Obese Type 2 Diabetic Rats To Increased Myocardial Fatty Acid Metabolism, Sriram Devanathan, Samuel T. Nemanich, Attila Kovacs, Nicole Fettig, Robert J. Gropler, Kooresh I. Shoghi

Open Access Publications

No abstract provided.


The Essential, Nonredundant Roles Of Rig-I And Mda5 In Detecting And Controlling West Nile Virus Infection, John S. Errett, Mehul S. Suthar, Aimee Mcmillan, Michael S. Diamond, Michael Gale Jr Jan 2013

The Essential, Nonredundant Roles Of Rig-I And Mda5 In Detecting And Controlling West Nile Virus Infection, John S. Errett, Mehul S. Suthar, Aimee Mcmillan, Michael S. Diamond, Michael Gale Jr

Open Access Publications

No abstract provided.


Mechanisms Of Hypoglycemia-Associated Autonomic Failure In Diabetes, Philip E. Cryer Jan 2013

Mechanisms Of Hypoglycemia-Associated Autonomic Failure In Diabetes, Philip E. Cryer

Open Access Publications

No abstract provided.


The Unusual Dynamics Of Parasite Actin Result From Isodesmic Polymerization, Kristen M. Skillman, Christopher I. Ma, Daved H. Fremont, Karthikeyan Diraviyam, John A. Cooper, David Sept, L. David Sibley Jan 2013

The Unusual Dynamics Of Parasite Actin Result From Isodesmic Polymerization, Kristen M. Skillman, Christopher I. Ma, Daved H. Fremont, Karthikeyan Diraviyam, John A. Cooper, David Sept, L. David Sibley

Open Access Publications

No abstract provided.


Three Dimensional Structure Prediction Of Fatty Acid Binding Site On Human Transmembrane Receptor Cd36, Zineb Tarhda, Oussama Semlali, Anas Kettani, Ahmed Moussa, Nada A. Abumrad, Azeddine Ibrahimi Jan 2013

Three Dimensional Structure Prediction Of Fatty Acid Binding Site On Human Transmembrane Receptor Cd36, Zineb Tarhda, Oussama Semlali, Anas Kettani, Ahmed Moussa, Nada A. Abumrad, Azeddine Ibrahimi

Open Access Publications

No abstract provided.


P19(Arf) And Ras(V12) Offer Opposing Regulation Of Dhx33 Translation To Dictate Tumor Cell Fate, Yandong Zhang, Anthony J. Saporita, Jason D. Weber Jan 2013

P19(Arf) And Ras(V12) Offer Opposing Regulation Of Dhx33 Translation To Dictate Tumor Cell Fate, Yandong Zhang, Anthony J. Saporita, Jason D. Weber

Open Access Publications

No abstract provided.


Neutrophils Control The Magnitude And Spread Of The Immune Response In A Thromboxane A2-Mediated Process, Chiao-Wen Yang, Emil R. Unanue Jan 2013

Neutrophils Control The Magnitude And Spread Of The Immune Response In A Thromboxane A2-Mediated Process, Chiao-Wen Yang, Emil R. Unanue

Open Access Publications

Neutrophils are obligate cells entering lymph nodes shortly after immunization with protein antigens in adjuvants, starting during the first hour and continuing for several days in two distinct waves. Previously, we demonstrated the strong suppressive effects of neutrophils on CD4 T cell and B cell responses, using either neutrophil-depleting antibodies or genetically neutropenic mice. In this study, we find that neutrophils are the major cells controlling the spread of T cell responses to distal lymph nodes. Although in the presence of neutrophils, ∼75% of the response was restricted to the draining node, in their absence, most of the response was …


Retracted Article: The Bcl11a Transcription Factor Directly Activates Rag Gene Expression And V(D)J Recombination, Baeck-Seung Lee, Joseph D. Dekker, Bum-Kyu Lee, Vishwanath R. Iyer, Barry P. Sleckman, Arthur L. Shaffer Iii, Gregory C. Ippolito, Philip W. Tucker Jan 2013

Retracted Article: The Bcl11a Transcription Factor Directly Activates Rag Gene Expression And V(D)J Recombination, Baeck-Seung Lee, Joseph D. Dekker, Bum-Kyu Lee, Vishwanath R. Iyer, Barry P. Sleckman, Arthur L. Shaffer Iii, Gregory C. Ippolito, Philip W. Tucker

Open Access Publications

No abstract provided.


The Role Of The Immune Response In Age-Related Macular Degeneration, Scott M. Whitcup, Akrit Sodhi, John P. Atkinson, V Michael Holers, Debasish Sinha, Barbel Rohrer, Andrew D. Dick Jan 2013

The Role Of The Immune Response In Age-Related Macular Degeneration, Scott M. Whitcup, Akrit Sodhi, John P. Atkinson, V Michael Holers, Debasish Sinha, Barbel Rohrer, Andrew D. Dick

Open Access Publications

No abstract provided.


A Novel Carboxyl-Terminal Heptapeptide Initiates The Regulated Secretion Of Lh From Unique Sub-Domains Of The Er, Albina Jablonka-Shariff, Irving Boime Jan 2013

A Novel Carboxyl-Terminal Heptapeptide Initiates The Regulated Secretion Of Lh From Unique Sub-Domains Of The Er, Albina Jablonka-Shariff, Irving Boime

Open Access Publications

No abstract provided.


Transcription Coactivators P300 And Cbp Are Necessary For Photoreceptor-Specific Chromatin Organization And Gene Expression, Anne K. Hennig, Guang-Hua Peng, Shiming Chen Jan 2013

Transcription Coactivators P300 And Cbp Are Necessary For Photoreceptor-Specific Chromatin Organization And Gene Expression, Anne K. Hennig, Guang-Hua Peng, Shiming Chen

Open Access Publications

No abstract provided.


To The Root Of The Curl: A Signature Of A Recent Selective Sweep Identifies A Mutation That Defines The Cornish Rex Cat Breed, Barbara Gandolfi, Hasan Alhaddad, Verena K. Affolter, Jeffrey Brockman, Jens Haggstrom, Shannon E. K. Joslin, Amanda L. Koehne, James C. Mullikin, Catherine A. Outerbridge, Wesley C. Warren, Leslie A. Lyons Jan 2013

To The Root Of The Curl: A Signature Of A Recent Selective Sweep Identifies A Mutation That Defines The Cornish Rex Cat Breed, Barbara Gandolfi, Hasan Alhaddad, Verena K. Affolter, Jeffrey Brockman, Jens Haggstrom, Shannon E. K. Joslin, Amanda L. Koehne, James C. Mullikin, Catherine A. Outerbridge, Wesley C. Warren, Leslie A. Lyons

Open Access Publications

No abstract provided.


Development And Characterization Of A Chemically Defined Food For Drosophila, Wen-Chih Lee, Craig A. Micchelli Jan 2013

Development And Characterization Of A Chemically Defined Food For Drosophila, Wen-Chih Lee, Craig A. Micchelli

Open Access Publications

No abstract provided.


Monitoring Metabolic Responses To Chemotherapy In Single Cells And Tumors Using Nanostructure-Initiator Mass Spectrometry (Nims) Imaging, Peter J. O'Brien, Michelle Lee, Mary E. Spilker, Cathy C. Zhang, Zhengming Yan, Timothy C. Nichols, Wenlin Li, Caroline H. Johnson, Gary J. Patti, Gary Siuzdak Jan 2013

Monitoring Metabolic Responses To Chemotherapy In Single Cells And Tumors Using Nanostructure-Initiator Mass Spectrometry (Nims) Imaging, Peter J. O'Brien, Michelle Lee, Mary E. Spilker, Cathy C. Zhang, Zhengming Yan, Timothy C. Nichols, Wenlin Li, Caroline H. Johnson, Gary J. Patti, Gary Siuzdak

Open Access Publications

No abstract provided.


Murine Norovirus Infection Does Not Cause Major Disruptions In The Murine Intestinal Microbiota, Adam M. Nelson, Michael D. Elftman, Amelia K. Pinto, Megan Baldridge, Patrick Hooper, Justin Kuczynski, Joseph F. Petrosino, Vincent B. Young, Christiane E. Wobus Jan 2013

Murine Norovirus Infection Does Not Cause Major Disruptions In The Murine Intestinal Microbiota, Adam M. Nelson, Michael D. Elftman, Amelia K. Pinto, Megan Baldridge, Patrick Hooper, Justin Kuczynski, Joseph F. Petrosino, Vincent B. Young, Christiane E. Wobus

Open Access Publications

No abstract provided.


Simultaneous Amplicon Sequencing To Explore Co- Occurrence Patterns Of Bacterial, Archaeal And Eukaryotic Microorganisms In Rumen Microbial Communities, Sandra Kittelmann, Henning Seedorf, William A. Walters, Jose C. Clemente, Rob Knight, Jeffrey I. Gordon, Peter H. Janssen Jan 2013

Simultaneous Amplicon Sequencing To Explore Co- Occurrence Patterns Of Bacterial, Archaeal And Eukaryotic Microorganisms In Rumen Microbial Communities, Sandra Kittelmann, Henning Seedorf, William A. Walters, Jose C. Clemente, Rob Knight, Jeffrey I. Gordon, Peter H. Janssen

Open Access Publications

No abstract provided.


Regional Control Of Drosophila Gut Stem Cell Proliferation: Egf Establishes Gssc Proliferative Set Point & Controls Emergence From Quiescence, Marie Strand, Craig A. Micchelli Jan 2013

Regional Control Of Drosophila Gut Stem Cell Proliferation: Egf Establishes Gssc Proliferative Set Point & Controls Emergence From Quiescence, Marie Strand, Craig A. Micchelli

Open Access Publications

No abstract provided.


Pgmra: A Web Server For (Phenotype X Genotype) Many-To-Many Relation Analysis In Gwas, Javier Arnedo, Coral Del Val, Gabriel Alejandro De Erausquin, Rocio Romero-Zaliz, Dragan Svrakic, Claude Robert Cloninger, Igor Zwir Jan 2013

Pgmra: A Web Server For (Phenotype X Genotype) Many-To-Many Relation Analysis In Gwas, Javier Arnedo, Coral Del Val, Gabriel Alejandro De Erausquin, Rocio Romero-Zaliz, Dragan Svrakic, Claude Robert Cloninger, Igor Zwir

Open Access Publications

No abstract provided.


Dopamine D1 Receptor Gene Variation Modulates Opioid Dependence Risk By Affecting Transition To Addiction, Feng Zhu, Chun-Xia Yan, Yi-Chong Wen, Jiayin Wang, Jinbo Bi, Ya-Ling Zhao, Lai Wei, Cheng-Ge Gao, Wei Jia, Sheng-Bin Li Jan 2013

Dopamine D1 Receptor Gene Variation Modulates Opioid Dependence Risk By Affecting Transition To Addiction, Feng Zhu, Chun-Xia Yan, Yi-Chong Wen, Jiayin Wang, Jinbo Bi, Ya-Ling Zhao, Lai Wei, Cheng-Ge Gao, Wei Jia, Sheng-Bin Li

Open Access Publications

No abstract provided.


Calcium Oxalate Crystals Induce Renal Inflammation By Nlrp3-Mediated Il-1Β Secretion, Shrikant R. Mulay, Onkar P. Kulkarni, Khader V. Rupanagudi, Adriana Migliorni, Murthy N. Darispudi, Akosua Vilaysane, Daniel Muruve, Yan Shi, Fay Munro, Helen Liapis, Hans-Joachim Anders Jan 2013

Calcium Oxalate Crystals Induce Renal Inflammation By Nlrp3-Mediated Il-1Β Secretion, Shrikant R. Mulay, Onkar P. Kulkarni, Khader V. Rupanagudi, Adriana Migliorni, Murthy N. Darispudi, Akosua Vilaysane, Daniel Muruve, Yan Shi, Fay Munro, Helen Liapis, Hans-Joachim Anders

Open Access Publications

No abstract provided.


Novel Resistance Functions Uncovered Using Functional Metagenomic Investigations Of Resistance Reservoirs, Erica C. Pehrsson, Kevin J. Forsberg, Molly K. Gibson, Sara Ahmadi, Gautam Dantas Jan 2013

Novel Resistance Functions Uncovered Using Functional Metagenomic Investigations Of Resistance Reservoirs, Erica C. Pehrsson, Kevin J. Forsberg, Molly K. Gibson, Sara Ahmadi, Gautam Dantas

Open Access Publications

No abstract provided.


Effects Of Serum And Compressive Loading On The Cartilage Matrix Synthesis And Spatiotemporal Deposition Around Chondrocytes In 3d Culture, Peihui Wu, Elizabeth Delassus, Debabrata Patra, Weiming Liao, Linda J. Sandell Jan 2013

Effects Of Serum And Compressive Loading On The Cartilage Matrix Synthesis And Spatiotemporal Deposition Around Chondrocytes In 3d Culture, Peihui Wu, Elizabeth Delassus, Debabrata Patra, Weiming Liao, Linda J. Sandell

Open Access Publications

No abstract provided.


Comparison Of Thermodilution Measured Extravascular Lung Water With Chest Radiographic Assessment Of Pulmonary Oedema In Patients With Acute Lung Injury, Lisa M. Brown, Carolyn S. Calfee, James P. Howard, Thelma R. Craig, Michael A. Matthay, Daniel F. Mcauley Jan 2013

Comparison Of Thermodilution Measured Extravascular Lung Water With Chest Radiographic Assessment Of Pulmonary Oedema In Patients With Acute Lung Injury, Lisa M. Brown, Carolyn S. Calfee, James P. Howard, Thelma R. Craig, Michael A. Matthay, Daniel F. Mcauley

Open Access Publications

No abstract provided.