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Articles 2791 - 2820 of 4253
Full-Text Articles in Entire DC Network
Gpr126 Functions In Schwann Cells To Control Differentiation And Myelination Via G-Protein Activation, Amit Mogha, Andrew E. Benesh, Chinmoy Patra, Felix B. Engel, Torsten Schoneberg, Ines Liebscher, Kelly R. Monk
Gpr126 Functions In Schwann Cells To Control Differentiation And Myelination Via G-Protein Activation, Amit Mogha, Andrew E. Benesh, Chinmoy Patra, Felix B. Engel, Torsten Schoneberg, Ines Liebscher, Kelly R. Monk
Open Access Publications
No abstract provided.
Cd47 Plays A Critical Role In T-Cell Recruitment By Regulation Of Lfa-1 And Vla-4 Integrin Adhesive Functions, Veronica Azcutia, Matthew Routledge, Marcie R. Williams, Gail Newton, William A. Frazier, Andre Manica, Kevin J. Croce, Charles A. Parkos, Angela B. Schmider, Melissa V. Turman, Roy J. Soberman, Francis W. Luscinskas
Cd47 Plays A Critical Role In T-Cell Recruitment By Regulation Of Lfa-1 And Vla-4 Integrin Adhesive Functions, Veronica Azcutia, Matthew Routledge, Marcie R. Williams, Gail Newton, William A. Frazier, Andre Manica, Kevin J. Croce, Charles A. Parkos, Angela B. Schmider, Melissa V. Turman, Roy J. Soberman, Francis W. Luscinskas
Open Access Publications
No abstract provided.
A Novel Hap1-Tsc1 Interaction Regulates Neuronal Mtorc1 Signaling And Morphogenesis In The Brain, Luis A. Mejia, Nadia Litterman, Yoshiho Ikeuchi, Luis De La Torre-Ubieta, Eric J. Bennett, Chi Zhang, J. Wade Harper, Azad Bonni
A Novel Hap1-Tsc1 Interaction Regulates Neuronal Mtorc1 Signaling And Morphogenesis In The Brain, Luis A. Mejia, Nadia Litterman, Yoshiho Ikeuchi, Luis De La Torre-Ubieta, Eric J. Bennett, Chi Zhang, J. Wade Harper, Azad Bonni
Open Access Publications
No abstract provided.
Distinct Balance Of Excitation And Inhibition In An Interareal Feedforward And Feedback Circuit Of Mouse Visual Cortex, Weiguo Yang, Yarimar Carrasquillo, Bryan M. Hooks, Jeanne M. Nerbonne, Andreas Burkhalter
Distinct Balance Of Excitation And Inhibition In An Interareal Feedforward And Feedback Circuit Of Mouse Visual Cortex, Weiguo Yang, Yarimar Carrasquillo, Bryan M. Hooks, Jeanne M. Nerbonne, Andreas Burkhalter
Open Access Publications
No abstract provided.
The Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is A Potent Allosteric Modulator Of N-Methyl-D-Aspartate Receptors, Steven M. Paul, James J. Doherty, Albert J. Robichaud, Gabriel M. Belfort, Brian Y. Chow, Rebecca S. Hammond, Devon C. Crawford, Andrew J. Linsenbardt, Hong-Jin Shu, Yukitoshi Izumi, Steven J. Mennerick, Charles F. Zorumski
The Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is A Potent Allosteric Modulator Of N-Methyl-D-Aspartate Receptors, Steven M. Paul, James J. Doherty, Albert J. Robichaud, Gabriel M. Belfort, Brian Y. Chow, Rebecca S. Hammond, Devon C. Crawford, Andrew J. Linsenbardt, Hong-Jin Shu, Yukitoshi Izumi, Steven J. Mennerick, Charles F. Zorumski
Open Access Publications
No abstract provided.
Structure And Function Of The Smoothened Extracellular Domain In Vertebrate Hedgehog Signaling, Sigrid Nachtergaele, Daniel M. Whalen, Laurel K. Mydock, Zhonghua Zhao, Tomas Malinauskas, Kathiresan Krishnan, Philip W. Ingham, Douglas F. Covey, Christian Siebold, Rajat Rohatgi
Structure And Function Of The Smoothened Extracellular Domain In Vertebrate Hedgehog Signaling, Sigrid Nachtergaele, Daniel M. Whalen, Laurel K. Mydock, Zhonghua Zhao, Tomas Malinauskas, Kathiresan Krishnan, Philip W. Ingham, Douglas F. Covey, Christian Siebold, Rajat Rohatgi
Open Access Publications
No abstract provided.
Dopamine-Dependent Compensation Maintains Motor Behavior In Mice With Developmental Ablation Of Dopaminergic Neurons, Judith P. Golden, Joseph A. Demaro Iii, Amanda Knoten, Masato Hoshi, Elizabeth Pehek, Eugene M. Johnson Jr, Robert W. Gereau Iv, Sanjay Jain
Dopamine-Dependent Compensation Maintains Motor Behavior In Mice With Developmental Ablation Of Dopaminergic Neurons, Judith P. Golden, Joseph A. Demaro Iii, Amanda Knoten, Masato Hoshi, Elizabeth Pehek, Eugene M. Johnson Jr, Robert W. Gereau Iv, Sanjay Jain
Open Access Publications
No abstract provided.
Pathogenic Cd4+ T Cells Recognizing An Unstable Peptide Of Insulin Are Directly Recruited Into Islets Bypassing Local Lymph Nodes, James F. Mohan, Boris Calderon, Mark S. Anderson, Emil R. Unanue
Pathogenic Cd4+ T Cells Recognizing An Unstable Peptide Of Insulin Are Directly Recruited Into Islets Bypassing Local Lymph Nodes, James F. Mohan, Boris Calderon, Mark S. Anderson, Emil R. Unanue
Open Access Publications
No abstract provided.
Down-Regulation Of Plcγ2-Β-Catenin Pathway Promotes Activation And Expansion Of Myeloid-Derived Suppressor Cells In Cancer, Aude-Helene Capietto, Seokho Kim, Dominic E. Sanford, David C. Linehan, Masaki Hikida, Tomohiro Kumosaki, Deborah V. Novack, Roberta Faccio
Down-Regulation Of Plcγ2-Β-Catenin Pathway Promotes Activation And Expansion Of Myeloid-Derived Suppressor Cells In Cancer, Aude-Helene Capietto, Seokho Kim, Dominic E. Sanford, David C. Linehan, Masaki Hikida, Tomohiro Kumosaki, Deborah V. Novack, Roberta Faccio
Open Access Publications
No abstract provided.
Nanoscale Protein Architecture Of The Kidney Glomerular Basement Membrane, Hani Suleiman, Lei Zhang, Robyn Roth, John E. Heuser, Jeffrey H. Miner, Andrey S. Shaw, Adish Dani
Nanoscale Protein Architecture Of The Kidney Glomerular Basement Membrane, Hani Suleiman, Lei Zhang, Robyn Roth, John E. Heuser, Jeffrey H. Miner, Andrey S. Shaw, Adish Dani
Open Access Publications
No abstract provided.
Murine Cytomegalovirus Protein Pm92 Is A Conserved Regulator Of Viral Late Gene Expression, Travis J. Chapa, Yi-Cheih Perng, Anthony R. French, Dong Yu
Murine Cytomegalovirus Protein Pm92 Is A Conserved Regulator Of Viral Late Gene Expression, Travis J. Chapa, Yi-Cheih Perng, Anthony R. French, Dong Yu
Open Access Publications
No abstract provided.
Nuclear Ubiquitination By Fbxl5 Modulates Snail1 Dna Binding And Stability, Rosa Vinas-Castells, Alex Frias, Estefania Robles-Lanuza, Kun Zhang, Gregory D. Longmore, Antonio Garcia De Herreros, Victor M. Diaz
Nuclear Ubiquitination By Fbxl5 Modulates Snail1 Dna Binding And Stability, Rosa Vinas-Castells, Alex Frias, Estefania Robles-Lanuza, Kun Zhang, Gregory D. Longmore, Antonio Garcia De Herreros, Victor M. Diaz
Open Access Publications
No abstract provided.
Latent Gammaherpesvirus 68 Infection Induces Distinct Transcriptional Changes In Different Organs, Susan P. Canny, Gautam Goel, Tiffany A. Reese, Xin Zhang, Ramnik Xavier, Herbert W. Virgin
Latent Gammaherpesvirus 68 Infection Induces Distinct Transcriptional Changes In Different Organs, Susan P. Canny, Gautam Goel, Tiffany A. Reese, Xin Zhang, Ramnik Xavier, Herbert W. Virgin
Open Access Publications
No abstract provided.
Continuous Cyclic Mechanical Tension Increases Ank Expression In Endplate Chondrocytes Through The Tgf-Β1 And P38 Pathway, H Xu, X Zhang, H Wang, Y Zhang, Y Shi, X Zhang
Continuous Cyclic Mechanical Tension Increases Ank Expression In Endplate Chondrocytes Through The Tgf-Β1 And P38 Pathway, H Xu, X Zhang, H Wang, Y Zhang, Y Shi, X Zhang
Open Access Publications
The normal ANK protein has a strong influence on anti-calcification. It is known that TGF-β1 is also able to induce extracellular inorganic pyrophosphate (ePPi) elaboration via the TGF-β1-induced ank gene expression and the mitogen-activated protein kinase (MAPK) signaling acts as a downstream effector of TGF-β1. We hypothesized that the expression of the ank gene is regulated by mechanics through TGF-β1-p38 pathway. In this study, we investigated the mechanism of short-time mechanical tension-induced ank gene expression. We found that the continuous cyclic mechanical tension (CCMT) increased the ank gene expression in the endplate chondrocytes, and there was an increase in the …
Bves And Ndrg4 Regulate Directional Epicardial Cell Migration Through Autocrine Extracellular Matrix Deposition, Emily C. Benesh, Paul M. Miller, Elise R. Pfaltzgraff, Nathan E. Grega-Larson, Hillary A. Hager, Bong Hwan Sung, Xianghu Qu, H. Scott Baldwin, Alissa M. Weaver, David M. Bader
Bves And Ndrg4 Regulate Directional Epicardial Cell Migration Through Autocrine Extracellular Matrix Deposition, Emily C. Benesh, Paul M. Miller, Elise R. Pfaltzgraff, Nathan E. Grega-Larson, Hillary A. Hager, Bong Hwan Sung, Xianghu Qu, H. Scott Baldwin, Alissa M. Weaver, David M. Bader
Open Access Publications
No abstract provided.
Histone Posttranslational Modifications And Cell Fate Determination: Lens Induction Requires The Lysine Acetyltransferases Cbp And P300, Louise Wolf, Wilbur Harrison, Jie Huang, Qing Xie, Ningna Xiao, Jian Sun, Lingkun Kong, Salil A. Lachke, Murali R. Kuracha, Venkatesh Govindarajan, Paul K. Brindle, Ruth Ashery-Padan, David C. Beebe, Paul A. Overbeek, Ales Cvekl
Histone Posttranslational Modifications And Cell Fate Determination: Lens Induction Requires The Lysine Acetyltransferases Cbp And P300, Louise Wolf, Wilbur Harrison, Jie Huang, Qing Xie, Ningna Xiao, Jian Sun, Lingkun Kong, Salil A. Lachke, Murali R. Kuracha, Venkatesh Govindarajan, Paul K. Brindle, Ruth Ashery-Padan, David C. Beebe, Paul A. Overbeek, Ales Cvekl
Open Access Publications
No abstract provided.
Evidence For Transgenerational Metabolic Programming In Drosophila, Jessica L. Buescher, Laura P. Musselman, Christina A. Wilson, Tieming Lang, Madeline Keleher, Thomas J. Baranski, Jennifer G. Duncan
Evidence For Transgenerational Metabolic Programming In Drosophila, Jessica L. Buescher, Laura P. Musselman, Christina A. Wilson, Tieming Lang, Madeline Keleher, Thomas J. Baranski, Jennifer G. Duncan
Open Access Publications
No abstract provided.
Molecular Characterization Of Articular Cartilage From Young Adults With Femoroacetabular Impingement, Shingo Hashimoto, Muhammad Farooq Rai, Corey S. Gill, Zhiqi Zhang, Linda J. Sandell, John C. Clohisy
Molecular Characterization Of Articular Cartilage From Young Adults With Femoroacetabular Impingement, Shingo Hashimoto, Muhammad Farooq Rai, Corey S. Gill, Zhiqi Zhang, Linda J. Sandell, John C. Clohisy
Open Access Publications
No abstract provided.
Glycogen Synthase Kinase 3Β Inhibition As A Therapeutic Approach In The Treatment Of Endometrial Cancer, Yan Yin, Nora T. Kizer, Premal H. Thaker, Katherine B. Chiappinelli, Kathryn M. Trinkaus, Paul J. Goodfellow, Liang Ma
Glycogen Synthase Kinase 3Β Inhibition As A Therapeutic Approach In The Treatment Of Endometrial Cancer, Yan Yin, Nora T. Kizer, Premal H. Thaker, Katherine B. Chiappinelli, Kathryn M. Trinkaus, Paul J. Goodfellow, Liang Ma
Open Access Publications
No abstract provided.
The Landscape Of Rna Polymerase Ii Transcription Initiation In C. Elegans Reveals Promoter And Enhancer Architectures, Ron A.-J Chen, Thomas A. Down, Przemyslaw Stempor, Q. Brent Chen, Thea A. Egelhofer, Ladeana W. Hillier, Tess E. Jeffers, Julie Ahringer
The Landscape Of Rna Polymerase Ii Transcription Initiation In C. Elegans Reveals Promoter And Enhancer Architectures, Ron A.-J Chen, Thomas A. Down, Przemyslaw Stempor, Q. Brent Chen, Thea A. Egelhofer, Ladeana W. Hillier, Tess E. Jeffers, Julie Ahringer
Open Access Publications
No abstract provided.
Relationships Among Hiv Infection, Metabolic Risk Factors, And Left Ventricular Structure And Function, William Todd Cade, Edgar Turner Overton, Kristin Mondy, Lisa De Las Fuentes, Victor G. Davila-Roman, Alan D. Waggoner, Dominic N. Reeds, Sherry Lassa-Claxton, Melissa J. Krauss, Linda R. Peterson, Keven E. Yarasheski
Relationships Among Hiv Infection, Metabolic Risk Factors, And Left Ventricular Structure And Function, William Todd Cade, Edgar Turner Overton, Kristin Mondy, Lisa De Las Fuentes, Victor G. Davila-Roman, Alan D. Waggoner, Dominic N. Reeds, Sherry Lassa-Claxton, Melissa J. Krauss, Linda R. Peterson, Keven E. Yarasheski
Open Access Publications
No abstract provided.
What's New In Spine Surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, Jeffrey C. Wang
What's New In Spine Surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, Jeffrey C. Wang
Open Access Publications
No abstract provided.
Camera-Port Site Metastasis Of A Renal-Cell Carcinoma After Robot-Assisted Partial Nephrectomy, Joseph B. Song, Youssef S. Tanagho, Eric H. Kim, Phillip H. Abbosh, Phillip H. Abbosh, Goutham Vemana, R. Sherburne Figenshau
Camera-Port Site Metastasis Of A Renal-Cell Carcinoma After Robot-Assisted Partial Nephrectomy, Joseph B. Song, Youssef S. Tanagho, Eric H. Kim, Phillip H. Abbosh, Phillip H. Abbosh, Goutham Vemana, R. Sherburne Figenshau
Open Access Publications
No abstract provided.
Global Analysis Of Drosophila Cys2-His2 Zinc Finger Proteins Reveals A Multitude Of Novel Recognition Motifs And Binding Determinants, Ryan G. Christensen, Gary D. Stormo, Et Al
Global Analysis Of Drosophila Cys2-His2 Zinc Finger Proteins Reveals A Multitude Of Novel Recognition Motifs And Binding Determinants, Ryan G. Christensen, Gary D. Stormo, Et Al
Open Access Publications
No abstract provided.
Protective Effect Of Surfactant Protein D In Pulmonary Vaccinia Virus Infection: Implication Of A27 Viral Protein, Julien Perino, Nicole M. Thielens, Erika Crouch, Danièle Spehner, Jean-Marc Crance, Anne-Laure Favier
Protective Effect Of Surfactant Protein D In Pulmonary Vaccinia Virus Infection: Implication Of A27 Viral Protein, Julien Perino, Nicole M. Thielens, Erika Crouch, Danièle Spehner, Jean-Marc Crance, Anne-Laure Favier
Open Access Publications
No abstract provided.
Evolutionarily Novel Functional Networks In The Human Brain?, Dante Mantini, Maurizio Corbetta, Gian Luca Romani, Guy A. Orban, Wim Vanduffel
Evolutionarily Novel Functional Networks In The Human Brain?, Dante Mantini, Maurizio Corbetta, Gian Luca Romani, Guy A. Orban, Wim Vanduffel
Open Access Publications
Primate evolution has been accompanied by complex reorganizations in brain anatomy and function. Little is known, however, about the relationship between anatomical and functional changes induced through primate evolution. Using functional magnetic resonance imaging, we assessed spatial and temporal correspondences of cortical networks in humans and monkeys. We provided evidence for topologically and functionally correspondent networks in sensory-motor and attention regions. More specifically, we revealed a possible monkey equivalent of the human ventral attention network. For other human networks, such as the language and the default-mode networks, we detected topological correspondent networks in the monkey, but with different functional signatures. …
Fatty Acid Transport Protein 4 (Fatp4) Prevents Light-Induced Degeneration Of Cone And Rod Photoreceptors By Inhibiting Rpe65 Isomerase, Songhua Li, Jungsoo Lee, Yongdong Zhou, William C. Gordon, James M. Hill, Nicolas G. Bazan, Jeffrey H. Miner, Minghao Jin
Fatty Acid Transport Protein 4 (Fatp4) Prevents Light-Induced Degeneration Of Cone And Rod Photoreceptors By Inhibiting Rpe65 Isomerase, Songhua Li, Jungsoo Lee, Yongdong Zhou, William C. Gordon, James M. Hill, Nicolas G. Bazan, Jeffrey H. Miner, Minghao Jin
Open Access Publications
Although rhodopsin is essential for sensing light for vision, it also mediates light-induced apoptosis of photoreceptors in mouse. RPE65, which catalyzes isomerization of all-trans retinyl fatty acid esters to 11-cis-retinol (11cROL) in the visual cycle, controls the rhodopsin regeneration rate and photoreceptor susceptibility to light-induced degeneration. Mutations in RPE65 have been linked to blindness in affected children. Despite such importance, the mechanism that regulates RPE65 function remains unclear. Through unbiased expression screening of a bovine retinal pigment epithelium (RPE) cDNA library, we have identified elongation of very long-chain fatty acids-like 1 (ELOVL1) and fatty acid transport protein 4 (FATP4), which …
The Disruption Of Celf6, A Gene Identified By Translational Profiling Of Serotonergic Neurons, Results In Autism-Related Behaviors, Joseph D. Dougherty, Susan E. Maloney, David F. Wozniak, Michael A. Rieger, Lisa Sonnenblick, Giovanni Coppola, Nathaniel G. Mahieu, Juliet Zhang, Jinlu Cai, Gary J. Patti, Brett S. Abrahams, Daniel H. Geschwind, Nathaniel Heintz
The Disruption Of Celf6, A Gene Identified By Translational Profiling Of Serotonergic Neurons, Results In Autism-Related Behaviors, Joseph D. Dougherty, Susan E. Maloney, David F. Wozniak, Michael A. Rieger, Lisa Sonnenblick, Giovanni Coppola, Nathaniel G. Mahieu, Juliet Zhang, Jinlu Cai, Gary J. Patti, Brett S. Abrahams, Daniel H. Geschwind, Nathaniel Heintz
Open Access Publications
The immense molecular diversity of neurons challenges our ability to understand the genetic and cellular etiology of neuropsychiatric disorders. Leveraging knowledge from neurobiology may help parse the genetic complexity: identifying genes important for a circuit that mediates a particular symptom of a disease may help identify polymorphisms that contribute to risk for the disease as a whole. The serotonergic system has long been suspected in disorders that have symptoms of repetitive behaviors and resistance to change, including autism. We generated a bacTRAP mouse line to permit translational profiling of serotonergic neurons. From this, we identified several thousand serotonergic-cell expressed transcripts, …
Role Of Trem1-Dap12 In Renal Inflammation During Obstructive Nephropathy, Alessandra Tammaro, Ingrid Stroo, Elena Rampanelli, Froilan Blank, Loes M. Butter, Nike Claessen, Toshiyuki Takai, Marco Colonna, Jaklien C. Leemans, Sandrine Florquin, Mark C. Dessing
Role Of Trem1-Dap12 In Renal Inflammation During Obstructive Nephropathy, Alessandra Tammaro, Ingrid Stroo, Elena Rampanelli, Froilan Blank, Loes M. Butter, Nike Claessen, Toshiyuki Takai, Marco Colonna, Jaklien C. Leemans, Sandrine Florquin, Mark C. Dessing
Open Access Publications
No abstract provided.
Functional Intersection Of Atm And Dna-Dependent Protein Kinase Catalytic Subunit In Coding End Joining During V(D)J Recombination, Baeck-Seung Lee, Eric J. Gapud, Yair Dorsett, Andrea Bredemeyer, Rosmy George, Oleg Osipovich, Eugene M. Oltz, Barry P. Sleckman, Et Al
Functional Intersection Of Atm And Dna-Dependent Protein Kinase Catalytic Subunit In Coding End Joining During V(D)J Recombination, Baeck-Seung Lee, Eric J. Gapud, Yair Dorsett, Andrea Bredemeyer, Rosmy George, Oleg Osipovich, Eugene M. Oltz, Barry P. Sleckman, Et Al
Open Access Publications
No abstract provided.