Digital Commons Network^™

Integrating Current Analyses Of The Breast Cancer Microbiome, Sidra Sohail

Master's Theses

Breast cancer is the leading cause of cancer death for women in the US. Many cancertypes have significant associations with their resident microbial communities - emerging evidence suggests that breast cancers also interact with the local tissue-associated microbiota. Studies have examined the relationship between breast cancer and its microbiome, however, the studies varied in their approaches used to evaluate these relationships. Microbiome research advances rapidly and analysis pipelines and databases are updated frequently. This dynamic environment makes inter-study comparisons and superficial evaluations challenging as no two studies are using the same standards for evaluation. Researchers have observed the microbiota of …

Taking It Too Far? Examining Derogation In Sexism Confrontations, Bayleigh Smith

Master's Theses

Sexism continues to be prevalent within today’s society (Bates, 2012; Crandall et al., 2018; World Health Organization, 2021), creating the need for methods to respond to such bias. Confrontation is one method that allows targets of sexism to stand up for themselves (Haslett & Lipman, 1997; Hyers, 2007; Kaiser & Miller, 2004), but often comes with social costs (e.g., being disliked, Czopp & Monteith, 2003; Dodd et al., 2001; Gulker et al., 2013; Kaiser & Miller, 2001). However, researchers have not dissected the factors that affect the social costs associated with confrontation (i.e., being labeled as a “sexist”, humor, or …

Role Of Tetraspanins In Sars-Cov-2 Fusion And Entry, Marcos Saul Santiago Figueroa

Master's Theses

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the pandemic the world has been facing in recent years. Even as new countermeasures are developed, there is still much we don’t know in terms of its entry into host cells. Tetraspanins are transmembrane proteins that are near ubiquitous amongst cell types. They fulfill numerous roles, including that of a viral co-receptor. Here, we considered whether tetraspanins, specifically CD9, CD63, and CD81 influence SARS-CoV-2 fusion and entry. Using ACE2-LgBit and tetraspanin overexpressing EVs and HeLa cells, we find that the presence of excess tetraspanins inhibit fusion and entry. However, we …

Migration Across Institutions Of Race: How Immigrant Women From Latin America Construct Ethnoracial Self-Identities In Sending And Receiving Societies, Juanita Vivas Bastidas

Master's Theses

How does immigration affect perceptions of self? In this study, I explore the processes by which immigrants construct ethnoracial self-identities in sending societies, an individual’s country of origin, and receiving societies, an individual’s country of destination. For my exploration, I conduct eleven life history and cognitive interviews of immigrant women from Spanish-speaking countries located in Latin America. Mainly, I find that the women in my study construct ethnoracial self-identities throughout their lives informed by their socialization into myths of racial democracy present in both locations and contradicting interactions, which take place in local organizations such as families, schools, and workplaces. …

To Be Fair: Colorism And Online Dating Among Young South Asians, Kajal S. Patel

Master's Theses

Online dating is rooted in first impressions through images. Because of this, users of these apps tend to alter their profile pictures to fit a certain criteria that they believe will attract more matches. For people of color, this benchmark is based upon fair skin and European facial features. This has led me to ask, how is colorism reinforced in online dating apps for Indian Americans, and more specifically though, how are the users of these apps portraying themselves in their own profiles as it relates to colorism? Due to various factors Indians with darker skin tend to feel pressure …

Comparison Study Of Laboratory Testing Programs Exploring The Influence Of Initial Static Shear Stress On Liquefaction Triggering, Micaela Saqui

Master's Theses

Current state of practice for calculating liquefaction triggering and deformations is outlined in multiple published articles (Seed 1971, Youd et al. 2001, Idriss and Boulanger 2008, National Academies of Sciences 2016, etc.). These methods use a factor of safety analysis with the cyclic stress ratio (the cyclic stress caused by the earthquake normalized by the effective vertical stress in the soil) and the cyclic resistance ratio (the resistance of the soil normalized by the effective vertical stress in the soil). These cyclic ratios are calculated first for free-field sites (no external forces on the soil), then correction factors are used …

Removing Soluble Phosphorus From Tertiary Municipal Wastewater Using Phosphorus- Deprived, Filamentous Microalgae, Aloysia Ahern

Master's Theses

Harmful algal blooms (HABs) can be detrimental to ecosystems, human health, and economies. The low levels of phosphorus remaining in the effluent of municipal wastewater treatment plants can contribute to HAB formation. To achieve more complete phosphorus removal, an effluent treatment method has been proposed that uses phosphorus-deprived, filamentous microalgae to quickly assimilate soluble phosphorus to low concentrations. This study investigated two parameters that influence the feasibility of such a system: (1) the biomass growth productivity of algal cultures during the phosphorus deprivation period and (2) the correlation between the duration of this period and the phosphorus uptake rate by …

A Study Of Pressure Probe Response In Steady And Unsteady Flows, Michael T. Charonnat

Master's Theses

The objective of this thesis is two-fold: to analyze the directional calibration of a 3-hole probe in steady flow and to develop a method for the interpretation of measurements recorded with a novel, fast-response Pitot-type probe in unsteady, turbulent flow. Calibration data for the 3-hole probe’s two side ports was taken in the steady, non-turbulent region of a free jet and was evaluated for symmetry. In addition, data that was recorded using one side port in two independent calibration runs was compared to study repeatability. Misalignment was found between the nominally symmetric data sets, which may be the result of …

An Integrated Approach For Controlling Verticillium Wilt Of Strawberry, Jack T. Koster

Master's Theses

Strawberry (Fragaria x ananassa, Duch.) is an important crop in California, with more than 35,000 acres planted in 2018 resulting in a farm gate value of $3.1 billion. In 2020, California strawberry production accounted for more than 85% of national strawberry production and faces serious threats to production due to various soil-borne diseases. One such disease, Verticillium wilt, is caused by the fungal pathogen Verticillium dahliae and is commonly found in temperate zones around the world where strawberries are grown. Due to the phase-out of efficacious fumigants like methyl bromide, alternative disease management methods have become necessary to …

Analysis Of Current And Future Flood Hazard In The Sacramento-San Joaquin Delta, Nicholas L. Mcguire

Master's Theses

The primary motivation of this study is to estimate the current and future flood hazard throughout the Sacramento-San Joaquin Delta in the context of sea-level rise. I also analyzed the effects of storm surge and river flow on extreme events to better understand how these events originate and vary spatially and in time. To address this goal, I combined digital water level records (primarily 1983-present) with archival data collected by the California Department of Water Resources (1929-1983) to reevaluate flood hazard in the Delta and investigate the possible sensitivity of the region different sea-level rise projections. Available archival records from …

Determination Of Fungicide Resistance In Botrytis Cinerea On Wine Grapes In California's Central Coast Region, Evelyn Alvarez-Mendoza

Master's Theses

Botrytis bunch rot, caused by Botrytis cinerea, is a fungal disease that primarily affects the fruit of wine grapes. Infection of fruit consequently results in reduced yields and wine quality. These factors lead to significant economic losses for growers which prompts the implementation of management practices to control the disease. One objective of this study was to evaluate the level of resistance that populations of B. cinerea in the Central Coast region showed to various chemicals. A fungicide assay was conducted to determine resistant phenotypes to six fungicide active ingredients (pyrimethanil, iprodione, fenhexamid, fludioxonil, trifloxystrobin, boscalid). Thirty-five (2020) and …

Design And Analysis Of A Discrete, Pcb-Level Low-Power, Microwave Cross-Coupled Differential Lc Voltage-Controlled Oscillator, Pavin Singh Virdee

Master's Theses

Radio Frequency (RF) and Microwave devices are typically implemented in Integrated Circuit (IC) form to minimize parasitics, increase precision and tolerances, and minimize size. Although IC fabrication for students and independent engineers is cost-prohibitive, an abundance of low-cost, easily accessible printed circuit board (PCB) and electronic component manufacturers allows affordable PCB fabrication.

While nearly all microwave voltage-controlled oscillator (VCO) designs are IC-based, this study presents a discrete PCB-level cross-coupled, differential LC VCO to demonstrate this more affordable and accessible approach. This thesis presents a 65 mW, discrete component VCO PCB with industry-comparable RF performance. A phase noise of -103.7 dBc/Hz …

Cofermentation, Post-Alcoholic, And Post-Malolactic Fermentation Blending Of Malbec, Merlot And Petite Sirah Wines, Armando Arturo Vega-Osorno

Master's Theses

A two-year study was conducted to assess the effects of cofermentation on red wine varietals. During the winemaking process, wines can be made from two or more varieties by picking, crushing and fermenting them together, a practice known as cofermentation. They can also be blended either after the completion of alcoholic fermentation or after malolactic fermentation. In the first year of the study, two grape varieties, Merlot (Mer), and Malbec (Mal) were cofermented. On the second year, a third varietal, Petite Sirah (PS) was also studied. Cofermented wines containing every possible binomial combination of the varietals was made and one …

Hydrologic Response Of Little Creek To The 2020 Czu Lightning Complex Fire At The Swanton Pacific Ranch, Kylie E. Dupuis

Master's Theses

In this study, stage, streamflow, and precipitation data was collected from small watersheds in the Swanton Pacific Ranch for the first two hydrologic years following the 2020 CZU Lightning Complex. The Little Creek watershed was setup for high-resolution data collection with four separate stage gauge sites (Main Stem, North Fork, South Fork, and Upper North Fork) and four rain gauge sites (Al Smith House, Ridgeline, Upper North Fork, and Landing 23). Stage gauge sites were also established at Queseria, Archibald, and Mill creeks. Preliminary post-fire rating curves were developed for the four sites of Little Creek. The Main Stem (MS) …

Mechanisms Of Substrate Selectivity And Transport By Escherichia Coli Atp- Binding Cassette (Abc) Transporter Metni, Yuchun Chen

Master's Theses

ABC transporters are central in many cellular functions including nutrient uptake, signal transduction membrane assembly, and cellular detoxification. Both structural and functional studies have revealed insights into the high-affinity uptake mechanism of the MetNI methionine ABC transporter. Using the energy from ATP binding and hydrolysis, the MetNI-Q system can import L-Met, D-Met, and other methionine derivatives against concentration gradients. Many mechanistic studies of ABC transporter propose a model in which cognate binding proteins sequester substrates in the periplasm and deliver them to the transporter. In contrast, recent in vivo and crystallographic studies of MetNI-Q suggest that some substrates may be …

Thermodynamic And Structural Quantification Of Metal Ions Binding To The Antimicrobial Peptide Calcitermin, Sohee Choi

Master's Theses

Over the past several decades the number of antibiotic resistant bacteria has grown dramatically, in part due to the over-prescription of antibiotics. This rise in antibiotic resistance has led to development of novel antibiotics. An attractive alternative to treat bacterial infections may be the use of antimicrobial peptides due their little-known resistance from bacteria. One such peptide is calcitermin (VAIALKAAHYHTHKE), a 15-residue peptide found in human airways. Calcitermin has antimicrobial properties that target Gram-positive bacteria and is most active in acidic buffer (pH 5.4) due to protonation of its three histidine residues, which allows it to interact with the negatively …

Ncaa Di Assistant Coaches' Understanding Of Mental Performance And Mental Health Services, Heather Hill

Master's Theses

The National Collegiate Athletic Association (NCAA) has acknowledged the importance of providing student-athletes with psychological services throughout their athletic careers (NCAA, n.d.). Two vital services for student-athletes are mental performance services that are focused on sport-related issues and mental health services that are centered around personal issues (Sudano & Miles, 2017). Previous literature around mental performance and mental health services has not distinguished between them, making it difficult to understand key stakeholders’ perceptions and knowledge of both mental performance and mental health services. Assistant coaches play an important role in NCAA athletic departments and spend substantial amounts of time connecting …

Synthesis And Analysis Of Short Antimicrobial Peptides: Rr, Rika Igr, And Hq, Kathleen Pierce

Master's Theses

A significant impending threat to the public health system is the rise of multidrug resistant bacteria. An attractive potential option to combat this is antimicrobial peptides (AMPs). AMPs are peptide chains with lengths that range from 10 to 70 amino acid residues that show antimicrobial activity. AMPs tend to have less toxicity than other antibiotic therapies, have a broader range of activity, and have a decreased resistance development by the target cells. Short AMPs are especially attractive due to their stability as well as their ability to penetrate cell membranes. With a wide range of possible AMPs available, further characterization …

Smart Spine Tape: Active Wearable Posture Monitoring For Prevention Of Low Back Pain And Injury, Samuel J. Borda

Master's Theses

Back pain and injury are a global health issue and are a leading cause of work and activity absence. Prevention would not only save those affected from the burden of pain and discomfort, but would also save people from loss of over 290 million workdays annually and save the healthcare system billions of dollars in expenses per year. Successful research and development of a wearable technology capable of comprehensively monitoring spinal postures that are leading causes of back pain and injury can result in prevention of mild to severe back pain and injury for high-risk people. To accomplish this, the …

Machine Learning And Software Solutions For Data Quality Assessment In Cern’S Atlas Experiment, Cary Randazzo

Master's Theses

The Large Hadron Collider (LHC) is home to multiple particle physics experiments designed to verify the standard model and push our understanding of the universe to its limits. The ATLAS detector is one of the large general-purpose experiments that make use of the LHC and generates a significant amount of data as part of its regular operations. Prior to physics analysis, this data is cleaned through a data assessment process which involves significant operator resources. With the evolution of the field of machine learning and anomaly detection, there is great opportunity to upgrade the ATLAS Data Quality Monitoring Framework to …

Upland Migration Of Coastal Marshes As A Response To Sea Level Rise And Fire Management: Past, Present, And Predicted, Devin Jen

Master's Theses

Coastal marshes are one of the most productive and intensively used ecosystems in the world. However, they are under threat due to natural and anthropogenic stressors, such as sea level rise (SLR). SLR can cause marshes to drown, converting them to open water. Marshes can respond to SLR through landward migration when suitable habitat is available. My research focuses on the landward migration pattern and mechanisms. I evaluated the historical land cover changes at the Grand Bay National Estuarine Research Reserve and the Pascagoula River delta over two-time intervals since 1955 and focused on the forest-marsh dynamics. I found that …

Effects Of Shoreline Development And Freshwater Discharge On Nekton Assemblage And Trophic Structure In A Northern Gulf Of Mexico Estuary, Glenn Schumacher

Master's Theses

Coastal salt marshes support a diversity of nekton and facilitate critical ecosystem functions but are threatened by shoreline development and climate change. Therefore, coastal ecosystem managers have begun incentivizing the use of living shorelines (LS), erosion control structures incorporating native plantings, to mitigate ecological consequences of marsh loss. However, post-restoration climate changes may shift habitat templates and negate positive effects of ecosystem restoration. I evaluated the ecology nekton along LS, natural marshes, hardened shorelines and greyed shorelines within Biloxi Bay, Mississippi, during a high freshwater discharge (HFD) period by comparing nekton assemblage (using species richness, Shannon-Wiener diversity, and relative abundance), …

Alt-Right Of The_Donald And Authoritarian Communists On Reddit: Internet Memes To Build Community, Joshua Hendricks

Master's Theses

This project infuses Lacanian psychoanalysis further into the rhetorical study by exploring authoritarian discourses on Reddit. I analyze the alt-right community that found a home on the subreddit r/The_Donald and chart their discourse as it shaped from the quarantine to the establishment of an independent forum called TheDonald.win. I selected memes and the comments around them to build the analysis. The second aspect of this thesis examines authoritarian communist discourse on Reddit. The leftist community splintered when r/socialism banned a community member because the person made catgirl art. The ban sent shockwaves through the leftist community on Reddit and generated …

Investigation Of Dead Ocean Quahogs (Arctica Islandica) Shells On The Mid-Atlantic Bight Continental Shelf, Alyssa Leclaire

Master's Theses

Ocean quahogs, Arctica islandica, are a long-lived, widely dispersed, biomass dominate in the Mid-Atlantic; therefore, quahog shells are valuable resources for studying climate change over time. Recently, dead ocean quahog shells were discovered south and inshore of the present biogeographic range of this animal. The presence of ocean quahog shells outside the current range is presumably a consequence of past regressions and transgressions of the Cold Pool, the bottom-trapped, cool body of water that allows boreal animals to live at lower latitudes. Dead ocean quahog shells were collected offshore of the DelMarVa Peninsula then radiocarbon-dated, evaluated for taphonomic condition, …

A Bioarchaeological Investigation Of The Courtney-Anderson Cemetery, Lauren Scott

Master's Theses

Located in Perry County, Mississippi, the Anderson Family Cemetery represents an abandoned turn-of-the-century Piney Woods cemetery. The cemetery is located on land once owned by the Courtney and Anderson families, who farmed the area until it was taken under eminent domain by the United States government in 1942. The purpose of this thesis is to present three osteobiographies created from human remains and material culture recovered from three graves excavated from within the cemetery in 2022 to explore the lifeways of rural Piney Woods families of Mississippi at the turn-of-the-century.

Among the graves explored, one did not contain evidence of …

Age-Based Comparison Of The Motivations, Self-Efficacy, And Quality Of Life In Bariatric Surgery Candidates, Sheena K. Bling

Master's Theses

Overweight and obesity is a worldwide epidemic that is negatively impacting individuals’ health and quality of life. Much research has been conducted regarding the effects of diet and exercise for weight loss, with current research providing evidence in favor of bariatric surgery for severely obese adults and children. The purpose of this project is to understand participants motivating factors, anticipated post-surgery success and anticipated changes in physical, social and mental health. The objectives were to describe participants’ motivations for pursuing bariatric surgery, describe participants level of confidence with postsurgical diet implementation, and compare participants anticipated post-surgery changes in quality of …

Evaluating Traditional And Novel Modalities Of Self-Monitoring In Females With Low-Literacy & Obesity: A Feasibility Study, Anita H. Kelleher

Master's Theses

This study aimed to determine the feasibility of three distinct self-monitoring modalities employed as part of a weight-loss intervention among Spanish- and Mixtec-speaking women with low-no literacy who were overweight or obese (body mass index, BMI> 25). Primary outcomes assessed include self-monitoring adherence, weight, body composition, and diet quality. Participants (n=18) were recruited from the Cal Poly Women and Infants Mobile Health Unit, and contacted if they had a BMI> 25 and did not attend school beyond elementary level (6th grade). Upon enrollment, participants were asked to attend a weekly meeting at which the lifestyle intervention was delivered by a …

The Immigrant - Original Score, Jared Lane

Master's Theses

On April 9th, 2022, The Immigrant – Original Score was premiered in front of a live audience in Milne Auditorium on the campus of the University of Northern Colorado with thirteen performers and Jared Lane conducting. This new score was written for Charlie Chaplin’s 1917 film The Immigrant.1 While this score was written to encompass the spirit of Chaplin’s film, it was also intended to introduce this one-hundred-year-old film to modern audiences. The Immigrant – Original Score embodies a synthesis of the music of Chaplin’s day and modern film scoring techniques.

No Justice, No Peace: An Examination Of The Protestor Experience, Naya Russell-Coprich

Master's Theses

More than 95% of the protests that took place in the summer of 2020 were deemed peaceful. However, many of these protests ended with violent encounters with police officers (Major Cities Chiefs Association, 2020). The purpose of this research was to explore the experience of protestors in America. This study also sought to identify, if at all, the disparities present when deciding to use excessive force against protestors. The sample for this study included students from the University of Northern Colorado, who were 18 years of age or older, and have attended a protest in their lifetime. The final sample …

Mercury-Mediated Cyclization To 2-Isoxazolines, Abigail Palmer

Master's Theses

The isoxazoline ring has been utilized in many therapeutic agents. For example, it is the key structure in ISO-1, an anti-inflammatory agent with unique anti-Type 1 diabetes activity. There are two primary methods used for the synthesis of isoxazolines: transition metal free cycloadditions and transition metal-mediated cycloadditions and cyclizations. Most transition metal-mediated syntheses employ the use of palladium, gold, silver, or copper complexes as catalysts. The syntheses often require long reaction times and result in low yields with many impurities. In general, mercury-mediated syntheses typically have shorter reaction times and result in products with higher purity. This research investigated the …