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A Midsummer Night's Dream: A Transformative Process, Jacob Bigelow
A Midsummer Night's Dream: A Transformative Process, Jacob Bigelow
Graduate Theses, Dissertations, and Problem Reports (ETD)
This thesis document is a written account of my design process from start to finish for a production of A Midsummer Night's Dream by William Shakespeare. This production was a product of West Virginia University; School of Theater & Dance, and was presented in the Gladys G. Davis Theater in the Creative Arts Center in Morgantown, WV; the performances dates were November 19th-21st and December 2nd-7th 2014. This document includes my analysis of the script, the steps of the design process, the execution of the design, and finally my analysis of the process.
Intimate Empire: Women's Travel Writing And U.S. Imperialism 1880-1920, Andrea Bebell
Intimate Empire: Women's Travel Writing And U.S. Imperialism 1880-1920, Andrea Bebell
Graduate Theses, Dissertations, and Problem Reports (ETD)
This dissertation examines how several turn-of-century U.S. women journalists and travel writers represent U.S. imperialism in a range of locales, trafficking in prevailing discourses of gender and race to represent colonized Others and as they engage in a comparative analysis to evaluate women's status in the U.S. In doing so, I suggest that these women, largely overlooked in critical discourses on U.S. imperialism, nonetheless contributed to the U.S. imperial imaginary. By recuperating the work of "newspaper ladies" Margherita Hamm, Nellie Bly, and Mary Krout, and through a reconsideration of Edith Wharton's travel writing, I consider the complex ways that white …
Ion Mobility-Mass Spectrometry For Structural Characterization And Applied 'Omics: A Study In Neurodegenerative Diseases, James Russell Arndt Iii
Ion Mobility-Mass Spectrometry For Structural Characterization And Applied 'Omics: A Study In Neurodegenerative Diseases, James Russell Arndt Iii
Graduate Theses, Dissertations, and Problem Reports (ETD)
Huntington's disease is neurodegenerative disease caused by an expanded polyglutamine-coding CAG repeat in exon 1 of the huntingtin gene. Huntingtin exon 1 forms the primary toxic amyloid structure in Huntington's disease; disease severity is directly correlated with polyglutamine length. Recent works have shown that fully formed amyloid plaques may not represent the most toxic species in Huntington's disease; the most neurotoxic species may be small, diffuse oligomer (4 - 20 monomer units) that are precursors to amyloid plaques. While the polyglutamine region is undisputed as the primary constituent of amyloid structure, aggregation kinetics and morphology are regulated by the presence …
Evolution Of A Disintegrin And Metalloproteinase Gene Family In Vertebrates, Shashwati Bhattacharya
Evolution Of A Disintegrin And Metalloproteinase Gene Family In Vertebrates, Shashwati Bhattacharya
Graduate Theses, Dissertations, and Problem Reports (ETD)
A disintegrin and metalloproteinases (ADAMs) are a family of transmembrane proteins which have diverse functions in various tissues. They play important roles in cellular and developmental processes and are present in various species. ADAMs are classified according to their expression in tissues into the somatic ADAMs (sADAMs) and the testicular ADAMs (tADAMs). The sADAMs are expressed in somatic tissues, and the testicular ADAMs (tADAMs) are expressed predominantly in the testis. The tADAMs are further classified into Group I and Group II, based on the absence or presence of introns. The mechanism of evolution of the tADAMs was unknown. Using bioinformatics …
The Memory Wars: Debates On The Holocaust And The Legacy Of Anti-Semitism In Poland, Jonathan Andrew Bergquist
The Memory Wars: Debates On The Holocaust And The Legacy Of Anti-Semitism In Poland, Jonathan Andrew Bergquist
Graduate Theses, Dissertations, and Problem Reports (ETD)
The process of Vergangenheitsbewaltigung, or mastering the past, is often slow and painful. All too often nations have a tendency to celebrate their past triumphs while forgetting or marginalizing the most traumatic episodes of their histories. The case of Poland is particularly interesting---especially in connection to the disappearance of the country's minority Jewish heritage. Poland, of course, was the primary site of the Holocaust, and the nearly complete destruction of the country's once vast Jewish population, which had been the largest in the world, has left a troublesome legacy behind. How had such horrific crimes taken place on Polish soil? …
Hydrologic Response And Erosion Modeling Of Geomorphic Landform Reclamation In Mountainous Terrain, Alison E. Sears
Hydrologic Response And Erosion Modeling Of Geomorphic Landform Reclamation In Mountainous Terrain, Alison E. Sears
Graduate Theses, Dissertations, and Problem Reports (ETD)
Surface mining and valley-fill practices often lead to environmental impacts including headwater stream loss, increased flooding risk, and degraded downstream water quality. Geomorphic landform design (GLD) is an innovative reclamation technique proposed to lessen the impacts associated with surface mining and valley-fill activities. GLD incorporates mature landform shapes and created stream channels on site, imitating the function of the undisturbed landscape. The purpose of this research was to model GLDs in mountainous terrain and evaluate the hydrologic response and erosion potential of GLD in surface mining application. Computer modeling of valley-fill designs using geomorphic landform principles of a study site …
Kruppel-Like Factor 4 (Klf4) Regulates Protumorigenic Signaling In Triple-Negative Breast Cancer (Tnbc) Cells, Sriganesh B. Sharma
Kruppel-Like Factor 4 (Klf4) Regulates Protumorigenic Signaling In Triple-Negative Breast Cancer (Tnbc) Cells, Sriganesh B. Sharma
Graduate Theses, Dissertations, and Problem Reports (ETD)
The zinc-finger pluripotency factor Kruppel-like factor 4 (KLF4) exerts context dependent roles in the maintenance of tissue homeostasis and the pathobiology of many malignancies, including breast cancer. Despite the multitude of studies focused on the role of KLF4 across these contexts, the signaling programs that are regulated by this factor in breast cancer cells remain unclear. In this dissertation we deliniate three KLF4-dependent protumorigenic signaling axes that endow triple-negative breast cancer (TNBC) cells with enhanced capacity to resist cell stress.;In the first study (Chapter 2), we found that KLF4 promotes the expression of two microRNAs (miRs), miR-206 and miR-21 (miR-206/21), …
Evaluating Changes In Knowledge, Beliefs, And Behaviors Associated With Hpv Following An Educational Intervention Among Women, Crystal Sheaves
Evaluating Changes In Knowledge, Beliefs, And Behaviors Associated With Hpv Following An Educational Intervention Among Women, Crystal Sheaves
Graduate Theses, Dissertations, and Problem Reports (ETD)
Background: Prevalence of HPV is estimated to be 10-15% Americans. HPV is recognized as the causative agent in 99.7% of all cervical cancers. In 2006, a vaccine was released to prevent specific types of HPV that cause cervical cancer. Despite demonstrated vaccine safety and efficacy, vaccine rates are still low at less than 20% among women 18-26 years old. Vaccine uptake may be impacted by women's HPV knowledge and beliefs.;Aims: The purpose of this study was to evaluate changes in women's knowledge, beliefs, and behaviors associated with HPV following an educational intervention study. Specifically, the study was designed to evaluate …
Impact Evaluation Of I Am Moving, I Am Learning Using The Re-Aim Framework, Ishonte Allar
Impact Evaluation Of I Am Moving, I Am Learning Using The Re-Aim Framework, Ishonte Allar
Graduate Theses, Dissertations, and Problem Reports (ETD)
Background: Presently, there are a lack of preschool physical activity and nutrition programs documented in the literature. I am moving, I am Learning (IMIL) is a preschool physical activity and nutrition program used by many Head Start programs across the nation. The purpose of this study was to determine the reach, effectiveness, adoption, implementation, and maintenance (RE-AIM) of IMIL in the state of Illinois.;Methods: Employing a QUAL+ quan simultaneous mixed-methods design, data were collected via a statewide agency administrator survey, classroom teacher survey, parent surveys, and program staff focus groups that occurred within a single program in Rock Island, Illinois.;Results: …
Fish Communities As Indicators Of Ecological Health In West Virginia Rivers, Alison M. Anderson
Fish Communities As Indicators Of Ecological Health In West Virginia Rivers, Alison M. Anderson
Graduate Theses, Dissertations, and Problem Reports (ETD)
Anthropogenic altered landscapes from the extraction of natural resources, urbanization, agricultural development, dam construction, and general conversion from forested to non-forested landscape have resulted in the loss of biodiversity and changes in ecosystem function for aquatic environments. Throughout this research, we have used detailed landscape data and a large fish community dataset to develop management tools and analyses in order to evaluate the condition of rivers and streams in West Virginia.;For Chapter 1, we developed a fish-based Index of Biotic Integrity (IBI), a common ecological tool for assessing the health of fish communities, in order to inform state and federal …
Relating Urban Forests And Urban Tourism: Exploring People's Perceptions, Preferences And Movement In Washington Dc, Rogelio T. Andrada Ii
Relating Urban Forests And Urban Tourism: Exploring People's Perceptions, Preferences And Movement In Washington Dc, Rogelio T. Andrada Ii
Graduate Theses, Dissertations, and Problem Reports (ETD)
Exploring the connection between urban forests and urban tourism has not been given much attention in recent investigative efforts. This study is designed to describe, explore and explain the specific elements where these two fields converge. There is no better vehicle to do this than by eliciting data from people, who are collectively, the beneficiaries and clientele of these entities. Therefore, a face-to-face survey, spanning one year, collected data on people's perception, preferences, movement, demographics and trip background in a popular and busy city destination: Washington DC.;Data collection yielded 1,146 completed questionnaires out of 3,210 respondents who participated which sets …
Transformation Of A Pre-Algebra Developmental Mathematics Course That Led To The Redesign Of The Developmental Mathematics Program At A Rural Community College, Mary Beth Angeline
Transformation Of A Pre-Algebra Developmental Mathematics Course That Led To The Redesign Of The Developmental Mathematics Program At A Rural Community College, Mary Beth Angeline
Graduate Theses, Dissertations, and Problem Reports (ETD)
This dissertation documents the redesign of a developmental mathematics program at a rural community college and compares the course pass rates between the redesigned courses and the traditional lecture-based courses. A design and developmental methodology was used to chronicle changes to outcomes, learning environment, instructor role, and curricular practices over four course offerings that occurred over three semesters. Effectiveness of these changes was used to continually make corrections to the course structure, and make a case to expand the redesign of the course to the entire developmental mathematics program.
The Influence Of White-Tailed Deer On Plant Communities In West Virginia And Stakeholder Attitudes Toward Deer Management With Respect To Plant Conservation, Kelley Lynne Flaherty
The Influence Of White-Tailed Deer On Plant Communities In West Virginia And Stakeholder Attitudes Toward Deer Management With Respect To Plant Conservation, Kelley Lynne Flaherty
Graduate Theses, Dissertations, and Problem Reports (ETD)
White-tailed deer (Odocoileus virginianus) may impact plant species by reducing individual survival or reduce reproductive potential by feeding on flowering parts or seeds. Herbivory may benefit plant populations by increasing dispersal of seeds. The combination of these factors may influence the composition of native plant communities. The recovery of deer populations from near extirpation was seen as a wildlife management success story. However, the maintenance of abnormally high deer density levels over many years may have taken a toll on plant communities. Some biologists now question whether or not white-tailed deer could be considered overabundant in some parts of their …
Acute Sleep Organization Following Unanesthetized Circumcision Of Neonates, Margeaux M. Gray
Acute Sleep Organization Following Unanesthetized Circumcision Of Neonates, Margeaux M. Gray
Graduate Theses, Dissertations, and Problem Reports (ETD)
Sleep changes in response to environmental pressures and the needs of individuals. The adaptability of sleep is noticeable following largely stressful or adverse events, and is understood to facilitate recovery. Rapid changes in sleep occur in-utero, during the days following birth, and across the first few postnatal years. These rapid changes are considered adaptive and indicative of normal and healthy development. Elective surgical intervention, such as circumcision, may influence the organization and quality of sleep during this developmentally sensitive period. Neonates undergoing circumcision, a prevalent procedure in the U.S. (American Academy of Pediatrics Circumcision Policy Statement [AAP], 1999, 2005, 2012), …
Synergistic Inhibition Of Cyclooxygenases And Monoacylglycerol Lipase In Neuropathic Pain, Molly S. Crowe
Synergistic Inhibition Of Cyclooxygenases And Monoacylglycerol Lipase In Neuropathic Pain, Molly S. Crowe
Graduate Theses, Dissertations, and Problem Reports (ETD)
Neuropathic pain is caused by altered nerve function that often presents as allodynia, which is the painful perception of typically non-noxious stimuli. Neuropathic pain is commonly treated with GABA analogues, steroids, or non-steroidal anti-inflammatory drugs (NSAIDs). NSAIDs inhibit one or more cyclooxygenase (COX) enzymes and are effective, commonly used analgesics that have relatively fewer side effects than other treatments. However, chronic cyclooxygenase inhibition also causes gastrointestinal inflammation and increased risk of cardiac events. Like NSAIDs, cannabinoids have analgesic and anti-inflammatory properties and reduce neuropathic pain in preclinical models. The present study investigated the analgesic effects of inhibiting both monoacylglycerol lipase …
Experimentally-Induced Savoring And Its Impact On Positive Emotions, Cognitions, And Behaviors: Investigating Individual Differences In Effectiveness, Cara A. Palmer
Graduate Theses, Dissertations, and Problem Reports (ETD)
By broadening cognitions and actions, positive affect increases our ability to engage in novel behaviors and build resources, which can lead to better social relationships, better health, more success, and increased resilience (Fredrickson, 2001). Thus, finding ways to increase and maintain positive affect and its broadening effects is essential. One way to up-regulate positive affect is by savoring, or actively trying to prolong or intensify a positive feeling. Although savoring is associated with a number of positive outcomes, the nature of the relationship between savoring, positive affect, and the resulting cognitive effects is not well explored. Furthermore, while some preliminary …
Identification Of School Physical Activity Leader Competencies Using Concept Mapping, Kiel M. Illg
Identification Of School Physical Activity Leader Competencies Using Concept Mapping, Kiel M. Illg
Graduate Theses, Dissertations, and Problem Reports (ETD)
Background/Purpose: Various public health and educational organizations have called for the implementation of comprehensive approaches at the state, district, and school levels to promote physical education and physical activity among children and adolescents. Proponents have argued that physical education teachers are positioned to assume the role of director of physical activity in the school setting; however many physical educators do not see directing comprehensive school physical activity programs (CSPAP) as their responsibility, nor have they been formally trained to provide this measure of leadership. Furthermore, there is limited research on CSPAPs and the associated leadership roles integral to planning, implementing, …
Evolutionary Search Techniques With Strong Heuristics For Multi-Objective Feature Selection In Software Product Lines, Abdel Salam Sayyad
Evolutionary Search Techniques With Strong Heuristics For Multi-Objective Feature Selection In Software Product Lines, Abdel Salam Sayyad
Graduate Theses, Dissertations, and Problem Reports (ETD)
Software design is a process of trading off competing objectives. If the user objective space is rich, then we should use optimizers that can fully exploit that richness. For example, this study configures software product lines (expressed as feature models) using various search-based software engineering methods. Our main result is that as we increase the number of optimization objectives, the methods in widespread use (e.g. NSGA-II, SPEA2) perform much worse than IBEA (Indicator-Based Evolutionary Algorithm). IBEA works best since it makes most use of user preference knowledge. Hence it does better on the standard measures (hypervolume and spread) but it …
Explicit Disclosure In Retail Communication: Impact Of Undetermined Social Network Site Relationships On Branded Identity, Hannah R. Gnegy
Explicit Disclosure In Retail Communication: Impact Of Undetermined Social Network Site Relationships On Branded Identity, Hannah R. Gnegy
Graduate Theses, Dissertations, and Problem Reports (ETD)
One of the most impactful technologies to emerge from Web 2.0 developments has been the social network site. In traditional models of branded identity, it is assumed that there is a distinction made between the retailer and consumer (de Chernatony, 1999; Kapferer, 2008). However, social network sites allow for the formation of undetermined relationships in which the underlying role of a party may be unknown.;As social network sites continue to shape retail practices, a gap in knowledge exists regarding how models of branded identity need to be modified to meet the demands of these undetermined social network site relationships. Through …
The Effect Of Allopurinol And Inosine Administration On Xanthine Oxidoreductase Gene Expression, Mitochondrial Respiration, And Inflammation In Broiler Chickens, Tabatha Settle
Graduate Theses, Dissertations, and Problem Reports (ETD)
Birds have a remarkable longevity for their body size despite an increased body temperature, higher metabolic rate, and increased blood glucose concentrations. Theoretically, birds should sustain a much higher degree of oxidative damage yet do not, in part due to the powerful antioxidant, uric acid. As the end-product of purine degradation, uric acid is generated in the xanthine/hypoxanthine reactions catalyzed by xanthine oxiodreductase (XOR). In the first study, inosine, a purine precursor, was fed to 3 groups of 5 birds: Group 1 was fed 0 (control), Group 2, 0.6 mols inosine/kg feed (INO) and Group 3, INO treatment plus 50 …
Development Of The West Virginia University Small Microgravity Research Facility (Wvu Smirf), Kyle G. Phillips
Development Of The West Virginia University Small Microgravity Research Facility (Wvu Smirf), Kyle G. Phillips
Graduate Theses, Dissertations, and Problem Reports (ETD)
West Virginia University (WVU) has created the Small Microgravity Research Facility (SMiRF) drop tower through a WVU Research Corporation Program to Stimulate Competitive Research (PSCoR) grant on its campus to increase direct access to inexpensive and repeatable reduced gravity research. In short, a drop tower is a tall structure from which experimental payloads are dropped, in a controlled environment, and experience reduced gravity or microgravity (i.e. "weightlessness") during free fall. Currently, there are several methods for conducting scientific research in microgravity including drop towers, parabolic flights, sounding rockets, suborbital flights, NanoSats, CubeSats, full-sized satellites, manned orbital flight, and the International …
Polylactic Acid-Based Polymer Blends For Durable Applications, Adam Finniss
Polylactic Acid-Based Polymer Blends For Durable Applications, Adam Finniss
Graduate Theses, Dissertations, and Problem Reports (ETD)
There has been considerable scientific interest in both research and commercial communities as of late in the area of biologically based or sourced plastics. As the consumption of petroleum rises and concerns about climate change increase, this field is likely to grow even larger. One bioplastic that has received a great deal of attention is polylactic acid (PLA). In the past, this material was used mainly in medical or specialty applications, but advancements in manufacturing have led to a desire to use PLA more widely, especially in durable applications. Unfortunately, PLA has several drawbacks that hinder more widespread usage of …
Animal Dispersal Of American Ginseng (Panax Quinquefolius L.), Amy M. Hruska
Animal Dispersal Of American Ginseng (Panax Quinquefolius L.), Amy M. Hruska
Graduate Theses, Dissertations, and Problem Reports (ETD)
American ginseng (Panax quinquefolius L.) is a long-lived forest herb found throughout Appalachia, well-known for its reputation as a medicinal plant species. Harvest of ginseng for the international medicinal plant trade has been a significant contributor to population decline of the species. As a declining species with life-history traits similar to many other herbaceous perennials and both cultural and economic value, American ginseng has become a focal species for many demographic and conservation based studies. Seed dispersal is a critical component of ginseng demography lacking empirical evidence for potential dispersal mechanisms. To date, gravity is considered to be the primary …
Energy Intensity Determination In Wood Processing Sawmills, Ramakrishna Babu Maddula
Energy Intensity Determination In Wood Processing Sawmills, Ramakrishna Babu Maddula
Graduate Theses, Dissertations, and Problem Reports (ETD)
Energy intensity is an important aspect to wood products producing sawmills in the State of West Virginia. This research aims to facilitate the accurate measurement of electrical energy intensity in sawmills by means of energy analysis and diagnostics using various data acquisition devices on electrical motors used in the manufacturing processes. Close to 90% of the electrical energy used in a typical sawmill is consumed by motors alone. The energy intensity determination is being accomplished by data collection with respect to electrical energy consumption parameters as well as production parameters. The electrical energy consumption was recorded on all the major …
Does Cultural Self-Awareness Alter Instructional Design Decisions?, Antoinette Hando
Does Cultural Self-Awareness Alter Instructional Design Decisions?, Antoinette Hando
Graduate Theses, Dissertations, and Problem Reports (ETD)
This project looks at the influence background culture has on instructional designers. Current research supports the hypothesis that background culture affects learning preferences. This study approaches cultural background from the instructional designers' point of view. Using Hofstede's Model of Cultural Dimensions as a tool for understanding how culture influences our expectations in a classroom setting a survey was sent to subjects from various cultures to see if their design style correlated to the ranking given by Hofstede. The results were that background culture influenced the experiences of the participants and could be related to Hofstede's Model of Cultural Dimensions.
The Current Status Of Meat Processing Facilities In Agricultural Education Programs In West Virginia, Eleanor Nicole Porter
The Current Status Of Meat Processing Facilities In Agricultural Education Programs In West Virginia, Eleanor Nicole Porter
Graduate Theses, Dissertations, and Problem Reports (ETD)
West Virginia has become a model for the local food movement. With a push for more locally grown food, there is a need for more people to provide local agricultural services. A number of agricultural education programs in West Virginia are providing students with hands on training in the meat processing field. Currently there is little information on the knowledge and skill level of instructors operating high school meats processing facilities. Therefore, this study was conducted to determine the expertise of the instructors and to determine the training needs of these individuals in the area of meat processing. The purpose …
Post-Translational Modifications Of The Paired Box Transcription Factor 7 (Pax7) In Satellite Cells During The Repair Of Injured Skeletal Muscle, Justin E. Sperringer
Post-Translational Modifications Of The Paired Box Transcription Factor 7 (Pax7) In Satellite Cells During The Repair Of Injured Skeletal Muscle, Justin E. Sperringer
Graduate Theses, Dissertations, and Problem Reports (ETD)
Satellite cells are normally a quiescent skeletal muscle stem cell pool that upon activation rapidly proliferate and differentiate to repair damaged muscle fibers. The paired box transcription factor 7 (Pax7) is the canonical biomarker for quiescent, activated, and proliferating satellite cells and is rapidly down-regulated upon differentiation into myofibers. However, the factors that regulate the modulation of Pax7 are largely unknown. Post-translational modifications to Pax7 provide a viable means to activate or deactivate this transcription factor through the signaling cascade of skeletal muscle repair and regeneration. The sirtuin 1 (Sirt1) protein, a histone deacetylase, has been shown to be involved …
Computational Strategies For Faster Combustion Simulations With Detailed Chemistry, Jose A. Escobar-Vargas
Computational Strategies For Faster Combustion Simulations With Detailed Chemistry, Jose A. Escobar-Vargas
Graduate Theses, Dissertations, and Problem Reports (ETD)
Combustion of fossil fuels is still the biggest source of power generation in the world. However, pollutants released to the atmosphere from combustion represent a risk for human health and the environment. Hence it is desirable to design a combustor that produces the maximum useful thermal power output while keeping low concentration levels of harmful emissions such as CO, P.M., NOx, and SOx. In the past, combustor design was aided by the compilation of large sets of experimental data and the development of empirical correlations which is an expensive process. Nowadays numerical simulations have become an important tool in the …
Development Of A Remote Laboratory With The Integration Of Cloud Applications, Jeremy Thompson
Development Of A Remote Laboratory With The Integration Of Cloud Applications, Jeremy Thompson
Graduate Theses, Dissertations, and Problem Reports (ETD)
Distance learning has been a mode of education since its inception at Pennsylvania State University in 1892. What started as a simple correspondence course has blossomed into a globally accepted method of education. The need for remote laboratories is growing as more lab-intensive programs of study are searching for a distance learning alternative. The goal of this research is to establish the foundation of a remote laboratory in the Mechanical and Aerospace Engineering Department at West Virginia University. The main objectives are to develop simple, easy-to-use graphical user interfaces to enhance the understanding of several concepts presented in the MAE …
Motivational Factors Contributing To The Choice Of Agriculturally Related Careers, Lacey J. Sims
Motivational Factors Contributing To The Choice Of Agriculturally Related Careers, Lacey J. Sims
Graduate Theses, Dissertations, and Problem Reports (ETD)
This study examined the motivational factors of college students who have chosen to study in an agriculturally related field. A descriptive research design using an online questionnaire was used for this study to determine factors which influenced career choice. Likert scale items were used to determine how motivating certain factors were for respondents in influencing their decision to study in an agriculturally related field. The Likert items were divided into five constructs: family influence, self-motivation, experience, use of skills, and career opportunities. Items within the five constructs were further analyzed to discover the top five motivational factors identified in each …