Digital Commons Network^™

Structural Transformations Of Synaptic Partners During Growth And Competition Of The Giant Nerve Terminal, The Calyx Of Held, In The Medial Nucleus Of The Trapezoid Body In The Developing Postnatal Mouse, Dakota Richard Jackson

Graduate Theses, Dissertations, and Problem Reports (ETD)

Across many parts of the nervous system, initial neural circuit assembly involves stereotyped stages of early axonal proliferation within target territories, selective reinforcement of a subset of inputs and the removal of exuberant or unneeded connections via either activity or experience-dependent mechanisms, in a process referred to as synaptic competition. The mechanisms and associated structural transformations that underlie and define these stages of neurodevelopment have been examined in a variety of brain regions including the peripheral neuromuscular junction, the central climbing fiber innervation of cerebellar Purkinje cells and retinal ganglion cell innervation of the thalamic lateral geniculate nucleus. Each of …

Impacts Of Bike Sharing On Transit Ridership, Moathe Salah Aljeri

Graduate Theses, Dissertations, and Problem Reports (ETD)

Biking is an active, environmentally friendly, and sustainable transportation mode that facilitates short utilitarian and recreational trips. As such, cities around the world have been implementing bicycle sharing/renting programs at stations in a wide network so that a traveler can mount one close to their origins and drop it off at a station nearest to their destinations. In addition, bike sharing programs can solve the first-mile and last-mile connectivity problems of transit modes. Such programs also enable short trips that were previously impossible without using transit modes. This research investigated the relationship between New York City (NYC) subway ridership and …

Genetic And Biochemical Characterization Of Ergot Alkaloid Synthesizing Fungi And Their Symbionts, Matthew Duane Maust

Graduate Theses, Dissertations, and Problem Reports (ETD)

Ergot alkaloids are fungal tryptophan derived toxins which affect mammalian circulation and neurotransmission. These compounds are biosynthesized by a conserved genetic pathway, known as the ergot alkaloid synthesis (EAS) pathway by fungi belonging to the ascomycete families Trichocomaceae and Clavicipitaceae. Several Ipomoea species and related plants in the morning glory family harbor vertically transmitted symbiotic fungi in the genus Periglandula, also members of Clavicipitaceae, that produce ergot alkaloids. Metabolomic analysis of seeds identified a previously uncharacterized glycoside form of the pharmaceutically important ergot alkaloid, ergonovine. Several species belonging to the fungal genus Metarhizium have recently been shown to have the …

Effect Of Particle Concentration, Sealing Condition And Breathing Rate On Total Inward Leakage For N95 Filtering Facepiece Respirators, Taoreed T. Lawal

Graduate Theses, Dissertations, and Problem Reports (ETD)

Several researchers have considered the relationship between total inward leakage (TIL) and other parameters such as sealing condition, particle concentration, type of particulate material breathing parameters, etc., however, there is dearth of information on the effects of varying particle concentration on the penetration efficiency of filtering facepiece respirators (FFRs), hence, this study aims to study the effect of varying NaCl particle concentration, sealing condition and breathing rate on the TIL as a result of the filtering efficiency of the filters.

To achieve this, we followed the sampling procedure used by He et al., 2014. Four different sealing conditions (SCs) namely; …

Music And Politics In Figure Skating: American And Soviet Nationalism, Cultural Diplomacy, And Identity At The Winter Olympics, 1968–1988, Mary Bridget Golden

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis situates figure skating, music, and Cold War politics during three separate Winter Olympic Games held in 1968, 1976, and 1988, examining the impact of this intersection on the sport of figure skating. Through a survey of seven Olympic medal-winning figure skating programs in the men’s and women’s single divisions and the pairs’ division, evidence of the relationship between politics and music is examined in the musical selections of the skaters’ programs. This thesis also explores the overwhelming prominence in skating programs of musical selections that appealed to the tastes of an elite majority during the Cold War, while …

Assessment Of Unmanned Aerial Systems And Lidar For The Utility Vegetation Management Of Electrical Distribution Rights-Of-Ways, Matthew R. Walker

Graduate Theses, Dissertations, and Problem Reports (ETD)

Utility Vegetation Management (UVM) is often the largest maintenance expense for many utilities. However, with advances in Unmanned Aerial Systems (UAS; or more commonly, “drones”) and lidar technologies, vegetation managers may be able to more rapidly and accurately identify vegetation threats to critical infrastructures. The goal of this study was to assess the utility of Geodetics’ UAS-lidar system for vegetation threat assessment for 1.6 km of a distribution electric circuit. We investigated factors which contribute to accurate tree crown detection and segmentation of trees from within an UAS-lidar derived point cloud, and the factors which contribute to accurate tree risk …

Rent And How To Pay It, Grant Austin Prodan

Graduate Theses, Dissertations, and Problem Reports (ETD)

This Document is a record of my process as the Technical Director of West Virginia University School of Theatre & Dance’s production of Rent. Included in the document is a detailed description of my budgeting, planning, and execution of the build as designed during a pandemic. The document is supported by images, schedules, drafting, and other paperwork.

Multi-Objective Optimization Of A Ridesharing System Performance, Mohammad Nasr Azadani

Graduate Theses, Dissertations, and Problem Reports (ETD)

Ridesharing is a shared vehicle service with the potential to meet the growing travel demand due to population increase, economic growth, and shortage in transportation infrastructure capacity. Compared to the current system of predominantly using personal vehicles, ridesharing services reduce the number of vehicles while providing mobility services to the same number of people with no additional investment in the transportation infrastructure. One of the big challenges in implementing ridesharing services is matching drivers and riders. Conflicts between matching-objectives to comply with the interests of diverse stakeholders influence the efficiency of ridesharing in a transportation system. This study investigates the …

Microbial Responses To Unconventional Oil And Gas Development May Alter Ecosystem Function In Headwater Streams, Rachel Michaels

Graduate Theses, Dissertations, and Problem Reports (ETD)

The demand for natural gas, and the need for efficient extraction, has led to the development of unconventional oil and natural gas (UOG) techniques. Due to the novelty of UOG, the potential impacts to freshwater ecosystems are not fully understood. We used a dual pronged approach to study the effects of UOG development on microbial biodiversity and function via a laboratory microcosm experiment and a survey study of streams with and without UOG development within their watersheds. The laboratory microcosm study simulated stream contamination with produced water, a byproduct of UOG operation, using sediment collected from one high water-quality stream …

Risk Assessment Of Architecture Technical Debt, Mrwan Omar Kh. Ben Idris

Graduate Theses, Dissertations, and Problem Reports (ETD)

Technical Debt (TD) is a metaphor that refers to short-term solutions in software development that may affect the software development life cycle cost. Researchers have found many TD types. These TD types include but are not limited to code debt (CD), design debt (DD), and architecture technical debt (ATD). Several methods have been used to detect technical debt, such as bad smells, software metrics, and code comments. Although TD has received many researchers’ attention, ATD has received less attention compared with CD and DD. We found a lack of tools to deal with ATD in contrast to CD and DD. …

Paleoecological Successions From Shallow-Marine Depositional Environments In Upper Silurian Carbonate Rocks Of Blair County, Pennsylvania, Shadya El-Ashkar

Graduate Theses, Dissertations, and Problem Reports (ETD)

Studies of paleoenvironment and paleoecology are important for investigating relationships between the different environmental and biological variables that influenced biodiversification patterns during the Silurian Period. The mixed carbonate and siliciclastic rocks of the Bloomsburg and Mifflintown Formations in central Pennsylvania represent transitions between carbonate ramp and deltaic settings. The goal of this study was to assess changes in depositional environment and paleoecology of an undescribed Bloomsburg/Mifflintown locality in Bellwood, Pennsylvania. In central Pennsylvania, the interfingered relationship of mixed carbonate and siliciclastic mudstones of the Mifflintown Formation with red fine-grained sandstones and shales of the Bloomsburg Formation presented challenges for deciphering …

Exploration Of Unknown Environments Using A Tethered Mobile Robot, Danylo Shapovalov

Graduate Theses, Dissertations, and Problem Reports (ETD)

Exploration with mobile robots is a well known field of research, but current solutions cannot be directly applied for tethered robots. In some applications, tethers may be very important to provide power or allow communication with the robot. This thesis presents an exploration algorithm that guarantees complete exploration of arbitrary environments within the length constraint of the tether, while keeping the tether tangle-free at all times. While a generalized algorithm that can be used with several exploration strategies is also proposed, the presented implementation uses a modified frontier-based exploration approach, where the robot chooses its next goal in the frontier …

A Study On The Hydrodynamics Of A Bench-Scale Top-Fed Bubbling Fluidized Bed Gasifier Using Biomass And Coal As Feedstocks, Ali Can Sivri

Graduate Theses, Dissertations, and Problem Reports (ETD)

The production of synthetic gas (syngas) from renewable or carbon-neutral sources can significantly reduce greenhouse and other emissions associated with conventional fuels. One of the most promising technologies to efficiently convert carbonaceous feedstocks such as biomass, coal, or municipal waste into syngas for transportation, power, heat, electricity generation, and or production of added-value chemicals is the bubbling fluidized-bed gasifier (BFBG). However, the gasification process inside a BFBG is a very complex high-temperature multiphase flow phenomena still not well understood, particularly when binary mixtures are investigated. As a result, despite the numerous correlations in the literature developed to predict the hydrodynamics …

Wv Dental Hygienists' Knowledge And Educational Approach For Pregnant Women, Isabella Hope Mcdaniel

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Adverse pregnancy outcomes have become a concern for dental professionals caring for pregnant women with poor oral health. Pregnant women may not be aware of their increased risk of bacterial infections in their oral tissues and how it could relate to adverse pregnancy outcomes such as pre- term birth (PTB) and low birthweight babies (LBW). Dental healthcare professionals need to be well informed of risk related to poor oral health and have confidence to effectively educate pregnant women. PTB and LBW babies account for 1 million infant deaths annually. It is the responsibility of dental healthcare professionals to be …

An Appraisal Of The Evolution Of Western Art Music In Nigeria, Agatha Onyinye Holland

Graduate Theses, Dissertations, and Problem Reports (ETD)

Nigeria has greatly evolved as an intercultural society given her history of colonization, the influence of foreign religion (Christianity and Islam, primarily) and the impact of globalization. Africa had her socio-cultural practices and art idioms before these foreign influences. For instance, music existed in everyday Africa as part of culture, religion, vocation, and drama. However, music never existed as an entity on its own. The culture of stage performers and audience never existed. This status quo changed with the introduction of Western art music through Christianity and education by the missionaries; since then, music assumed a bi-cultural status. This research …

Sergei Prokofiev's Third Piano Sonata, Op. 28: Stylistic Analysis And Performance Suggestions, Youngju Lee

Graduate Theses, Dissertations, and Problem Reports (ETD)

Sergei Prokofiev (1891-1953) was one of the greatest Russian pianists and composers of the twentieth century. He established his own musical style by combining classical form and modern compositional techniques. He composed a variety of piano music including nine piano sonatas. This paper is a study of the third piano sonata in A minor, op. 28.

Prokofiev’s music can be classified into three periods: a Russian Period, a Foreign Period, and a Soviet Period. It is possible to identify Prokofiev’s compositional styles by studying his piano sonatas because he composed piano sonatas during the entire course of his life. In …

The Fight Is Still On: An Ethical Analysis Of The American Civil Liberties Union’S Partisan Rhetoric In The Trump Era, Emily Charlotte Gerber

Graduate Theses, Dissertations, and Problem Reports (ETD)

The 2016 U.S. presidential election of Donald Trump generated a newfound surge in political advocacy that greatly benefitted certain nonprofits and grassroots organizations. One of these organizations was the American Civil Liberties Union, a nonpartisan nonprofit dedicated to protecting and defending civil liberties and rights in the U.S. The ACLU received an unprecedented number of donations following Election Day and has since pursued an aggressive campaign against President Donald Trump.

In order to explore this phenomenon, this thesis analyzed the ACLU’s rhetoric between Presidents George W. Bush and Donald Trump (both Republicans) and between Presidents Barack Obama (Democrat) and Donald …

Making Space For Writing: Makerspace Activities And Academic Language In A Middle School Science Classroom, Ashley Stewart

Graduate Theses, Dissertations, and Problem Reports (ETD)

Over recent decades, the maker movement has expanded from the private sector, libraries, and higher education institutions to K-12 schools. While many studies provide implications of STEM and maker activities and their effects on learning in informal settings, few have framed such investigations within the context of a makerspace in K-12 schools. Furthermore, few have investigated maker activities and writing, particularly in developing academic language features. Prior research suggests that secondary students struggle to apply academic language features. Meanwhile, they are motivated to engage in STEM and maker activities. This mixed methods case study attempted to make a connection between …

The Societal Influence On Individual Identity And The Relationship Of Costume Design In Caryl Churchill’S Cloud 9, Laura Kay Plikerd

Graduate Theses, Dissertations, and Problem Reports (ETD)

Cloud 9 is a play written by Caryl Churchill in 1978. Act one of the play takes place in 1870, British Occupied Africa and act two takes place in contemporary London. In our production, contemporary London was set in 2018. The dramatic shift in time during the two acts brings attention to the changing societal ideals and practices of each era. The costumes for this production of Cloud 9, illuminated the differences between the times by highlighting the stark differences in societally accepted fashion in the chosen time periods and regions.

In Cloud 9, the costumes create a …

Teacher As “Team Player”: An Early Career Teacher’S Refinement Of Critical Pedagogical Discourses, Keisha-Moraé Hopkins Kibler

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study centers on one early-career English language arts (ELA) teacher’s development of his critical pedagogical discourses (CPD) within the contextual discourses of collaboration and data informed instruction. These contextual discourses circulated assumptions of teaching and learning that are privileged by the political ideologies of the neo-liberal agenda, which can erode the democratic purposes of education. Data is drawn from an eight-month interpretive qualitative case study that included classroom observations and semi-structured interviews. The two research objectives for this study included: to come to understand the range of ways an early-career ELA teacher navigated the tensions between his belief and …

Design And Optimization Of Dynamic System For A One-Kw Free Piston Linear Engine Alternator-Gensets Program, Nima Zamani Meymian

Graduate Theses, Dissertations, and Problem Reports (ETD)

In power/energy systems, free-piston linear machines are referred to as a mechanism where the constrained crank motion is eliminated and replaced with free reciprocating piston motion. Depending on the application, the piston motion can be converted into other types of energy and includes compressed air/fluid, electricity, and high temperature/pressure gas. A research group at West Virginia University developed a free-piston linear engine alternator (LEA) in 1998 and have achieved significant accomplishment in the performance enhancement of the LEAs to date. The present LEA design incorporates flexure springs as energy restoration components and as bearing supports. The advantages of using flexure …

Experimental And Computational Exploration Of The Dilute Magnetic Delafossite Cual1-Xfexo2 Alloys, Mina Aziziha

Graduate Theses, Dissertations, and Problem Reports (ETD)

CuAlO₂ is among several ternary delafossites, which is a rare p-type semiconductor with potential applications as a transparent conductive oxide, photocatalyst, and spintronics when doped with transition metal ions. Reported in this thesis are results from our investigations of CuAl_1-xFe_xO₂ (x = 0 to1) with a focus on the x-dependence of structural, magnetic, vibrational, optical properties, and the role of defects and impurities. Samples are prepared by solid-state reactions.

We performed a complete study of magnetic properties to investigate the possibility of room temperature ferromagnetic alloys, which are used in …

Fundamental Studies On The Recovery Of Rare Earth Elements From Acid Mine Drainage, Xue Huang

Graduate Theses, Dissertations, and Problem Reports (ETD)

The Rare Earth Elements (REEs) are a group of 17 chemically similar elements that are essential raw materials for modern society. Given their increasing importance in civil and defense applications, many national governments, including the US, have denoted the REEs as critical materials and emphasized the need to identify and develop both conventional and unconventional resources to meet the growing demand. To address this challenge, the US Department of Energy has recently spearheaded efforts to evaluate the technical and economic feasibility of recovering REEs from coal and coal byproducts, which have been shown to contain REEs at an elevated concentration …

Cobalt-Catalyzed Aerobic Oxidative Cyclization Reactions Of Bisnucleophiles: New Methodologies And The Role Of Bisnucleophiles In O2 Activation, Jiaqi Liu

Graduate Theses, Dissertations, and Problem Reports (ETD)

Over the past few decades, transition metals have found wide applications in the development of selective oxidative transformations mediated by molecular oxygen. Due to the benign nature of molecular oxygen as an oxidant and an increasing awareness of green chemistry practice, tremendous progress has been made towards the development of Cu-and Pd-catalyzed aerobic oxidation reactions. As a first-row transition metal alternative to copper, cobalt has been employed in aerobic catalytic transformations for its cost-efficiency and earth abundance; however, redox-active mediators such as benzoquinone (BQ), N-hydroxyphthalimide (NHPI) or salen-type ligands are usually required. To date, reactions mediated by Co/O₂ catalytic …

Minocycline As A Treatment For Traumatic Brain Injury-Induced Impulsive And Attentional Deficits, Kristen M. Pechacek

Graduate Theses, Dissertations, and Problem Reports (ETD)

Traumatic brain injury (TBI) impacts millions worldwide and can cause lasting psychiatric symptoms. Chronic neuroinflammation is a characteristic of post-injury pathology and is positively associated with psychiatric conditions such as ADHD and bipolar disorder. Therefore, the current study sought to treat TBI-induced impulsivity and inattention using minocycline, an antibiotic with anti-inflammatory properties. Rats were trained on the five-choice serial reaction time task (5CSRT), a measure of motor impulsivity and attention. After behavior was stable on the 5CSRT, rats received either a bilateral frontal TBI or sham procedure. Minocycline was given at either 1 h post-injury or beginning at 8 weeks …

Evaluation Of Fitts’ Throughput As A Possible Performance Measure For Manual Assembly Tasks, Pradyumna Bettagere Jagadish

Graduate Theses, Dissertations, and Problem Reports (ETD)

Assembly lines are the backbone of the manufacturing sector. Workers at the assembly lines are expected to perform fast pace hand-arm exertions with precision and accuracy. To protect the workers from injuries, OSHA mandates the use of personal protective equipment (PPE) including gloves. Certain assembly operations require the use of special gloves. Some of these gloves can inhibit hand performance, further increasing the task difficulty. The Index of Difficulty (ID) is a metric measured in ‘bits’ quantifies task difficulty through the quotient of target width and target motion, i.e., distance travelled. The time required to complete the target motion is …

Factors Influencing Huntingtin Aggregation At Surfaces: Implications For Huntington’S Disease, Sharon E. Groover

Graduate Theses, Dissertations, and Problem Reports (ETD)

Huntington’s Disease (HD) is a genetic, neurodegenerative disease characterized by an abnormal polyglutamine (polyQ) expansion in the first exon of the huntingtin protein (htt). The polyQ domain facilitates aggregation and initiates the formation of a diverse collection of aggregate species, including fibrils, oligomers and annular aggregates. The first 17 amino acids of htt (Nt17) directly flank the polyQ domain and is a key factor in htt’s association to membranous structures. In addition to Nt17 being an amphipathic αhelix, it also promotes aggregation through self-association and contains numerous posttranslational modifications (PTMs) that can modulate toxicity and subcellular localization. For in depth …

Silver-Mediated Decarboxylation Reactions: Expanding Reaction Scope Through Kinetic Analysis, Robert Anthony Crovak

Graduate Theses, Dissertations, and Problem Reports (ETD)

Transition metal-catalyzed decarboxylative coupling reactions have received considerable attention in recent years as a method to obtain biaryl compounds. However, the oxidative version of this reaction class is still in its infancy, limited to specific substitution patterns on the benzoic acids – ortho-substitution - used in these transformations. This thesis describes our attempts to understand the key decarboxylation step of this important class of reactions. The first chapter of this thesis discusses an introduction into cross-coupling reactions, decarboxylative cross-coupling reactions, and outlines relevant physical organic parameters. The following chapter details the synthesis of a series of (1,10-phenanthroline)silver(benzoate) complexes. This chapter …

Synthesis And Characterization Of Pyridine Dipyrrolide Iron Complexes Relevant To Nitrene And Carbene Group Transfer, Brett M. Hakey

Graduate Theses, Dissertations, and Problem Reports (ETD)

The synthesis and electronic structures of the square-planar high-spin Fe^II complexes (^MesPDP^Ph)Fe(OEt₂) and (^MesPDP^Ph)Fe(thf) were investigated. Analysis of these compounds using a combination of ¹H NMR and ⁵⁷Fe Mössbauer spectroscopies, in conjunction with computational analysis, has resulted in a rationalization for their unusual electronic structures, which arise from the unique coordination environment enforced by the pyridine dipyrrolide chelate ligand.

The reactivity of (^MesPDP^Ph)Fe(thf) with organic azides has been probed and resulted in the isolation of an array of products that are consistent with …

Examining Provider-Patient Communication And Family Knowledge Of Treatment In Pediatric Asthma Care, Thomas W. Ewell

Graduate Theses, Dissertations, and Problem Reports (ETD)

Asthma knowledge is an essential factor in being able to consistently and effectively manage asthma symptoms over time, which in turn reduces asthma morbidity and improves quality of life. The way in which certain provider factors, such as communication strategies or techniques, may differentially impact pediatric patients and their caregivers has little in the way of prior investigation. The current study involves a secondary analysis from a larger project. This larger study included 45 pediatric asthma patients (ages 8-17 years; M = 11.79) and their primary caregiver recruited from pediatric asthma and allergy clinics within the WVU Medicine system to …