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Graduate Theses, Dissertations, and Problem Reports (ETD)

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Genetic Basis For Thermal Tolerance In Two Different Strains Of Rainbow Trout (Oncorhynchus Mykiss): Case Western And Kamloops, Paola Reale Aug 2012

Genetic Basis For Thermal Tolerance In Two Different Strains Of Rainbow Trout (Oncorhynchus Mykiss): Case Western And Kamloops, Paola Reale

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis examines the thermal tolerance based on how expression of Heat Shock Protein (HSP) 70 and HSP90 differ between two different strains of rainbow trout (Oncorhynchus mykiss), the Case Western strain and the Kamloops strain, and determines if cortisol levels affect HSP expression in red blood cells. The Case Western strain is considered the only warm water trout, only recently was any aspect of its thermal tolerance quantified. Porto (2012) determined critical thermal maxima (CTM) for the Case Western strain and found it to be about 0.15 °C higher than the Kamloops strain. This thesis is comprised of three …

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Physicochemical Properties Of Alaska Pollock (Theragra Chalcogramma) Surimi Seafood Nutrified With Powdered Cellulose Fiber And Omega-3 Polyunsaturated Fatty Acids, Alicia Debusca Aug 2012

Physicochemical Properties Of Alaska Pollock (Theragra Chalcogramma) Surimi Seafood Nutrified With Powdered Cellulose Fiber And Omega-3 Polyunsaturated Fatty Acids, Alicia Debusca

Graduate Theses, Dissertations, and Problem Reports (ETD)

Surimi is minced deboned fish meat that has been washed of lipids, sarcoplasmic proteins, and other impurities. Surimi seafood, also known as "imitation crabmeat", is widely enjoyed in the United States; however, it is not currently nutrified with fiber, omega-3 polyunsaturated fatty acids, and salt substitute. In the present study, preliminary experimentation was done to determine the optimal level of fiber addition. Powdered cellulose was added to Alaska Pollock surimi gels at levels of 0% (control), 2%, 4%, 6%, and 8% fiber. The objectives of this initial study were to determine effect of dietary fiber on 1) color and textural …

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Physiological And Genetic Changes In Poplar During Mycorrhizal Colonization Under Phosphorus Limitation, Shalaka Desai Aug 2012

Physiological And Genetic Changes In Poplar During Mycorrhizal Colonization Under Phosphorus Limitation, Shalaka Desai

Graduate Theses, Dissertations, and Problem Reports (ETD)

Poplar species and hybrids are intensively cultivated as renewable sources of biomass because of their rapid growth, extensive genetic variation and ease of propagation. However, the physiological mechanisms underlying soil stress resistance within these poplar species and hybrids are not yet understood. With the recent sequencing of the poplar genome, the use of this species in physiological stress resistance studies may help elucidate the underlying basis of stress resistance in a woody species. Further, although symbiotic mycorrhizal associations have farreaching ecological significance in forest ecosystems, our understanding of the influences of the association on the genetic basis of environmental stress …

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Modulation Of Cardiac Pacemaker Channels By Tyrosine Phosphorylation, Jianying Huang Aug 2012

Modulation Of Cardiac Pacemaker Channels By Tyrosine Phosphorylation, Jianying Huang

Graduate Theses, Dissertations, and Problem Reports (ETD)

Encoded by hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, the cardiac pacemaker current If is a major determinant of diastolic depolarization in sinus node myocytes and has a key role in the origin of heart beat. My dissertation consists of two chapters, focusing on the modulation of If and HCN channels by tyrosine phosphorylation, which is maintained by a fine balance between tyrosine kinases and phosphatases. Chapter 1 aims to investigate the role of Src tyrosine kinases in the regulation of sinus node If and HCN channels; Chapter 2 explores the modulation of ventricular If and HCN channels by a family of …

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Investigating Changes In Productivity Of An Old Growth Juniperus Stand: A Physiological And Isotopic Approach, Scott E. Spal Aug 2012

Investigating Changes In Productivity Of An Old Growth Juniperus Stand: A Physiological And Isotopic Approach, Scott E. Spal

Graduate Theses, Dissertations, and Problem Reports (ETD)

Forest ecosystems play a central role in the global carbon cycle and are a major part of the terrestrial carbon sink. For more accurate predictions of terrestrial C sequestration models require a mechanistic understanding of how carbon cycling in trees and forests responds to atmospheric CO 2, temperature, and precipitation. With this comes a need for a greater understanding of the physiological mechanisms involved with changes in forest productivity as trees and forests age. This research used an old growth stand of Juniperus virginiana (Eastern red cedar) in the Central Appalachian Mountains of West Virginia to examine how carbon assimilation …

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Cliff Ecology: Extent, Biota, And Recreation Of Cliff Environments In The New River Gorge, Wv, Peter W. Clark Aug 2012

Cliff Ecology: Extent, Biota, And Recreation Of Cliff Environments In The New River Gorge, Wv, Peter W. Clark

Graduate Theses, Dissertations, and Problem Reports (ETD)

The New River Gorge National River (NERI) contains an extensive network of exposed cliff-forming sandstone units, the most extensive in West Virginia and possibly within the entire Appalachian range. These cliff resources are critical to NERI's national significance, and contain specialized and potentially rare plant communities (Vanderhorst 2001; Mahan 2004; Vanderhorst, Jeuck, and Gawler 2007). This project investigates the spatial distribution of cliffs, associated plant (vascular and non-vascular) and lichen communities, and the impacts to cliff environments caused by recreational rock climbing.;Using LiDAR in a GIS, we mapped all cliffs in the northern extent of NERI, from Keeney's Creek to …

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Effect Of Rigor State, When Processed, On Rainbow Trout (Oncorhynchus Mykiss) Fillet Quality, Oluwatoyin E. Adebisi Aug 2012

Effect Of Rigor State, When Processed, On Rainbow Trout (Oncorhynchus Mykiss) Fillet Quality, Oluwatoyin E. Adebisi

Graduate Theses, Dissertations, and Problem Reports (ETD)

A study was conducted to investigate the effect of rigor development, at time of processing, on weight and length changes, proximate analysis, pH, K-value, color, and texture of rainbow trout (Oncorhynchus mykiss ) fillets. Texture of cooked fillets was characterized using two instrumental methods: Allo-kramer and Variable blade. Forty-five rainbow trout were harvested and immediately slaughtered using percussive stunning they were stored, following evisceration, at 4°C on ice. Fish were processed at 0, 24, and 48 h postharvest, and fillets were vacuumed packaged and stored for 2 days at 4°C. These storage treatments were applauded in the context of a …

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Reversible Myocardial Dysfunction In A Rodent Model Of Prenatal Stress, Jessalyn Marie Hadfield Aug 2012

Reversible Myocardial Dysfunction In A Rodent Model Of Prenatal Stress, Jessalyn Marie Hadfield

Graduate Theses, Dissertations, and Problem Reports (ETD)

Compelling clinical reports indicate that emotional/behavioral stress alone is sufficient to cause profound, but completely reversible myocardial dysfunction in selected individuals. A rodent cardiomyopathy model was previously reported by combining pre-natal and post-natal behavioral/restraint stress (Stress). A decrease in % FS (the ratio between the diameter of the left ventricle when it is relaxed and when it is contracted) by echocardiogram was previously reported, along with both systolic and diastolic dysfunction by catheter-based hemodynamics, as well as attenuated hemodynamic and inotropic responses to the beta adrenergic agonist, isoproterenol (ISO) in Stress compared with matched Controls. The p38mitogen-activated protein (MAP) kinase …

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Land As A Renewable Resource: Integrating Climate, Energy, And Profitability Goals Using An Agent-Based Netlogo Model, Inocencio Rodriguez Aug 2012

Land As A Renewable Resource: Integrating Climate, Energy, And Profitability Goals Using An Agent-Based Netlogo Model, Inocencio Rodriguez

Graduate Theses, Dissertations, and Problem Reports (ETD)

The objectives of this study center over the course of the beef production life cycle as a management strategy to optimize the financial and natural resource endowment on farms at the county level based on the data available. Although the application is to West Virginia, implications can be derived for other areas with similar resource endowments. The beef farms located in adjacent locations within a county are identified as suppliers of inputs to the farm of interest (or contracting farm) in order to provide the basic foundation for agglomeration economies.;Both an intertemporal component and a spatial component are involved since …

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Colloidal Nanocrystal Quantum Dots For High-Efficiency Optoelectronic Conversions, Yiqiang Zhang Aug 2012

Colloidal Nanocrystal Quantum Dots For High-Efficiency Optoelectronic Conversions, Yiqiang Zhang

Graduate Theses, Dissertations, and Problem Reports (ETD)

Monodispersed colloidal quantum dots (QDs) synthesized by low-cost solution methods have many attractive properties, including high wavelength tunability, efficient luminescence, narrow emission bandwidth, and strong broadband absorption. They therefore offer a new class of materials for efficient optoelectronic conversions in various devices, including light-emitting diodes (LEDs), photodetectors, and thin-film solar cells. Despite the recent rapid progress, the development of QD-based devices is still in its infancy. For instance, both the external quantum efficiency of QD-LEDs and power conversion efficiency of QD solar cells reported in the literature are only a few percent, far below those of state-of-the- art inorganic and …

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Risk Perception Among Sexually Abused Female Adolescents, Andrea M. Jones Aug 2012

Risk Perception Among Sexually Abused Female Adolescents, Andrea M. Jones

Graduate Theses, Dissertations, and Problem Reports (ETD)

Previous research investigating risk recognition in female victims of child sexual abuse has focused on college-aged women and young adults to the exclusion of adolescent females, who are just entering the stage where dating and sexual relationships are becoming important. Research with college-aged women and young adults has demonstrated that women with a history of child sexual abuse are less likely to detect risk cues in social environments. Understanding how adolescents perceive risky situations is important in preventing the trajectory from child sexual abuse to later adult victimization. It also is important to understand deficits in risk perception across a …

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Color-Blind: The Effects Of A Reporter's Race On Framing, Gregory A. Cranmer Aug 2012

Color-Blind: The Effects Of A Reporter's Race On Framing, Gregory A. Cranmer

Graduate Theses, Dissertations, and Problem Reports (ETD)

Previous literature has established the widespread use of frames that contrast athletes' physical (i.e., the "brawn" frame) and mental abilities (i.e., the "brain" frame) in mediated sports content, especially in verbal commentary. An athlete's race has been extensively studied as a key variable that determines which frames are implemented by media institutions, as Black athletes are framed in the brawn frame and White athletes are framed in the brain frame. The current study analyzed the presence, salience, and valence of brawn and brain frames of Heisman finalists in newspaper articles. This study extended previous research by examining (a) written content, …

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Factors Affecting Orthodontic Adherence In Appalachia, Breana M. Phillips Aug 2012

Factors Affecting Orthodontic Adherence In Appalachia, Breana M. Phillips

Graduate Theses, Dissertations, and Problem Reports (ETD)

Orthodontic intervention enhances not only esthetics and psychosocial health, but also improves the function of the human dentition. Many insurance programs now offer orthodontic coverage; however, proper adherence and good oral hygiene habits are poor among those Appalachian individuals undergoing orthodontic care. This research study was conducted to determine the contributing factors in poor orthodontic compliance in Appalachia. Investigators completed a retrospective chart review, assessing inactive orthodontic patients from 2007-2012 at a private practice in North Central West Virginia. The general dentist at this rural office practices both general dentistry, as well as, orthodontics. Information regarding demographics, form of payment, …

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The Association Of Social Anxiety And Parenting Factors With Adolescent Use Of Facebook, Brian Creasy Aug 2012

The Association Of Social Anxiety And Parenting Factors With Adolescent Use Of Facebook, Brian Creasy

Graduate Theses, Dissertations, and Problem Reports (ETD)

Computers and the Internet play a substantial role in how adolescents communicate with one another. Social networking websites, in particular, are a popular medium used by adolescents in which users can develop and maintain a large number of relationships from a single profile page. Facebook represents one of the most widely used social networking websites; however, little is known about the types of factors that are associated with the way in which adolescents use it. The present study examined the association of social anxiety and parenting with adolescent Facebook use. One hundred and sixty-two adolescents between the ages of 16 …

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Identification Of Early Behavioral Markers Of Anxiety And Social Withdrawal In Preschool Children, Chelsea M. Ale Aug 2012

Identification Of Early Behavioral Markers Of Anxiety And Social Withdrawal In Preschool Children, Chelsea M. Ale

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study examined an observational method for identifying specific behaviors to indicate social anxiety and social withdrawal in preschool children. During an interaction task with a novel adult, 28 children (ages 4 and 5) were observed for specific verbal and non-verbal behaviors (i.e., total utterances, commands, questions, unsolicited conversation, direct responses, eye gaze aversion, non-verbal response, physical distancing, freezing, smiling ) and global behaviors (i.e., shyness, volume or speech, and postural rigidity), theoretically relevant to early childhood social anxiety. Behaviors observed during the interaction task were examined in relation to the parent-reported Spence Preschool Anxiety Scale's social anxiety subscale (Spence, …

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Development And Testing Of A High Resolution Pet Detector For Prostate Imaging, Evan P. Delfino Aug 2012

Development And Testing Of A High Resolution Pet Detector For Prostate Imaging, Evan P. Delfino

Graduate Theses, Dissertations, and Problem Reports (ETD)

According to the American Cancer Society one in six men will be diagnosed with prostate cancer in their lifetime. Current methods for screening of prostate cancer including various PSA blood tests, as well as the digital rectal exam, are unreliability while current imaging modalities clinically employed (US, CT, MRI) are unable to localize intraprostatic cancer(s). Consequently, diagnosis via core needle biopsy is problematic and a game of chance at best. Therefore, in response to new radiopharmaceuticals applicable to both internal and external prostate cancer visualization and localization, novel prostate specific nuclear medical imagers are being developed.;The first prototype of a …

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Habitat Selection Of Male Eastern Wild Turkey (Meleagris Gallopavo Silvestris) In West Virginia, Jesse L. De La Cruz Aug 2012

Habitat Selection Of Male Eastern Wild Turkey (Meleagris Gallopavo Silvestris) In West Virginia, Jesse L. De La Cruz

Graduate Theses, Dissertations, and Problem Reports (ETD)

Eastern wild turkeys (Meleagris gallopavo silvestris) have been the focus of widespread research throughout their range, but research on male wild turkey home range size and habitat resource selection is limited in West Virginia. To address this lack of knowledge, I proposed the quantification of home range within a region (second-order) and core home range within a periphery (third-order) resource selection. Home ranges estimates and regional vector sampling grids were modeled against anthropomorphic land use and landscape cover features, land fragmentation, slope, and aspect raster data within the Geospatial Modeling Environment (GME) to derive proportional resource use and availability data.;West …

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Evaluation Of The Potential For Detection And Classification Of Ailanthus Altissima (Tree Of Heaven) Using Lidar Data, Cassidy Robert Rhea Aug 2012

Evaluation Of The Potential For Detection And Classification Of Ailanthus Altissima (Tree Of Heaven) Using Lidar Data, Cassidy Robert Rhea

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis compares methods for delineating and classifying the invasive, exotic tree Ailanthus altissima (tree of heaven), using attributes derived entirely from light detection and ranging (LiDAR) data. The accuracy of two image segmentation methods: 1) Tree variable window program (TreeVaW) and 2) watershed segmentation, and three classifications schemes: 1) classification and regression trees (CART) 2) artificial neural networks (NN) and 3) support vector machines (SVM) are compared. I found that generally the watershed segmentation method produced better segmentation results than the TreeVaW segmentation method, and that the CART classification was the most accurate overall classifier, although the SVM classification …

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A Retrospective Clinical Study To Evaluate Mineral Trioxide Aggregate (Mta) As A Direct Pulp Capping Agent In A One-Visit Protocol, Patrick J. Petley Aug 2012

A Retrospective Clinical Study To Evaluate Mineral Trioxide Aggregate (Mta) As A Direct Pulp Capping Agent In A One-Visit Protocol, Patrick J. Petley

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study was to demonstrate the long-term success that can be achieved by the use of Mineral Trioxide Aggregate (MTA) as a pulp capping agent, demonstrate the simplicity of the procedure, and overcome the commonly held objections of cost, difficult handling characteristics, and the need for two appointments to complete the procedure.;A single visit protocol was utilized in the completion of forty-eight pulp cap procedures with twenty-seven procedures available for recall. The MTA pulp cap was covered with glass ionomer liner and then restored with a bonded composite or amalgam. Teeth were evaluated for sensitivity to percussion, …

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Estimation Of Striped Bass (Morone Saxatilis) Diets Using Fatty Acid Signature Analysis, Edward J. Mcginley Aug 2012

Estimation Of Striped Bass (Morone Saxatilis) Diets Using Fatty Acid Signature Analysis, Edward J. Mcginley

Graduate Theses, Dissertations, and Problem Reports (ETD)

Accurate estimates of diets are essential for the management of fisheries, especially when this information is used to construct food webs for a system. Traditionally, these studies have relied on examining the stomachs contents through direct observation of sacrificed fish, or using instruments to "flush" the items from the stomach. These methods only provide information on the recent feeding history. Fatty acid analysis is a biochemical technique that offers promise for examining diets in fish over a longer time scale than just the last few prey species consumed. The goal of this dissertation was to examine the feasibility and efficacy …

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Pharmacological Characterization Of An Optimized Sigma Receptor Ligand, Michael Seminerio Aug 2012

Pharmacological Characterization Of An Optimized Sigma Receptor Ligand, Michael Seminerio

Graduate Theses, Dissertations, and Problem Reports (ETD)

Methamphetamine is an addictive psychostimulant drug with an increasing prevalence of abuse worldwide. Recent evidence has linked methamphetamine exposure to a wide array of neurological complications some of which lead to neurodegenerative changes in the brain and hyperthermia. Currently, there are no FDA approved pharmacologic agents to treat the effects of methamphetamine. Recent evidence has suggested methamphetamine may, in part, produce some of its effects through sigma receptors making them a potential target for pharmacological intervention. While our lab has shown a number of selective sigma receptor ligands can provide neuroprotection against the neurotoxic and behavioral effects of methamphetamine, limitations …

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C-Peptide Improves Hyperglycemia-Induced Endothelial Redox Balance By Preventing Mitochondrial Oxidative Stress And Enhancing Nadph Synthesis, Himani Vejandla Aug 2012

C-Peptide Improves Hyperglycemia-Induced Endothelial Redox Balance By Preventing Mitochondrial Oxidative Stress And Enhancing Nadph Synthesis, Himani Vejandla

Graduate Theses, Dissertations, and Problem Reports (ETD)

C-peptide, a by-product of insulin biosynthesis, has been shown to ameliorate diabetes-induced renal impairment. Yet, the mechanisms underlying this protective benefit remain unclear. Our studies have shown that C-peptide improved renal peritubular capillary blood flow and reduced vascular oxidants. NADPH (reduced nicotinamide adenine dinucleotide phosphate), appears to be critical to this effect via the actions of numerous vasoprotective systems. Further, our experiments in type I diabetic mice resulted in a significant reduction in renal endothelial NADPH that is subsequently restored with C-peptide. We hypothesized that C-peptide provides protection to renal cortical endothelial cells during type I diabetes by restoring the …

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Microfluidic Based Human Blood Plasma Separation, Ruizhi Zhong Aug 2012

Microfluidic Based Human Blood Plasma Separation, Ruizhi Zhong

Graduate Theses, Dissertations, and Problem Reports (ETD)

Microfluidic based biotechnologies have been widely applied for biological and biomedical research and applications because the physical scales of microfluidics are suitable for biological cells and provide the ability and flexibility to control spatiotemporal biochemical parameters. The current efforts for biosensor technologies are aiming to develop detection technologies directly from small volumes of the human fluids, such as blood, urea, and saliva, for accurate, fast, and affordable detection and analysis.;Human blood provides information and supports the functioning of human body, such as nourishing tissues, regulating organs activities and defending harmful material. Blood components are the prime interests for biosensor applications …

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The Critical Middle Years And The Relationship Of Early Access To Algebra On High School Math Course Completion And College Readiness, Kim Victoria Smith Green May 2012

The Critical Middle Years And The Relationship Of Early Access To Algebra On High School Math Course Completion And College Readiness, Kim Victoria Smith Green

Graduate Theses, Dissertations, and Problem Reports (ETD)

Many students who enroll in higher education are unprepared to meet the challenges of postsecondary education. The probability that students will make a successful transition from high school to college is linked to the degree to which their secondary educational experiences have prepared them for the expectations and demands they will encounter in college. National findings provide continuing evidence that focusing on improving student achievement in mathematics will positively impact college readiness. The main problem addressed in this quantitative study was how educators can best prepare students for college readiness. Since college readiness is highly dependent upon math achievement in …

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Feeding Female Growing Rats Different Sources Of Omega-3 Polyunsaturated Fatty Acids Affects Lung Fatty Acid Composition And Gene Expression, Maria L. Dalzot May 2012

Feeding Female Growing Rats Different Sources Of Omega-3 Polyunsaturated Fatty Acids Affects Lung Fatty Acid Composition And Gene Expression, Maria L. Dalzot

Graduate Theses, Dissertations, and Problem Reports (ETD)

Justification: The lungs are constantly exposed to oxidative stress and inflammation which increase the risk of lung damage. Omega-3 polyunsaturated fatty acids (n-3 PUFAs), found in different dietary sources, regulate the expression of various genes involved in eicosanoid production and oxidative stability.;Objective: to determine whether providing different sources of n-3 PUFAs will affect the fatty acid composition, inflammation and oxidation in the lungs of growing rats.;Methods: Growing (age 28 d) Sprague-Dawley rats were randomly assigned (n=10/group) to diets consisting of either corn oil (CO) or n-3 PUFA rich flaxseed (FO), krill (KO), salmon (SO) or tuna (TO) oil for 8 …

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Using Concept Mapping To Identify Action Steps For Physical Activity Promotion In Cancer Treatment, Sean J. Fitzpatrick May 2012

Using Concept Mapping To Identify Action Steps For Physical Activity Promotion In Cancer Treatment, Sean J. Fitzpatrick

Graduate Theses, Dissertations, and Problem Reports (ETD)

The benefits of exercise during and after cancer treatment represent research areas that have received increased attention throughout the past two decades. Numerous benefits have been observed for cancer survivors who are physically active (Speck, Courneya, Masse, Duval & Schmitz, 2010). Yet oncologists have been slow to incorporate exercise counseling into practice (Daley et al., 2007). The objective of this study was to gather input from both researchers and oncologists as to what needs to happen for exercise to become part of standard care once treatment ends. The concept mapping process developed by Trochim and Kane (2007) was utilized to …

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Coyote Diets In West Virginia, Geriann Albers May 2012

Coyote Diets In West Virginia, Geriann Albers

Graduate Theses, Dissertations, and Problem Reports (ETD)

Coyotes were not present in the mid-Atlantic region until the 1950s and little is known regarding their ecology in this region. My objective was to examine the diets of coyotes in West Virginia and to compare diets among regions and seasons as well as between age and sex. I also analyzed the occurrence of livestock in coyote diets and used logistic regression and Akaike's Information Criterion to analyze potential factors influencing livestock consumption by coyotes. In cooperation with the West Virginia Division of Natural Resources, USDA APHIS Wildlife Services, and hunters and trappers, I collected coyote scat and stomachs throughout …

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Bisphenol A Alters The Function And Expression Of Bk Channels In Vascular Smooth Muscle Through Membrane And Nuclear Signals, Shinichi Asano May 2012

Bisphenol A Alters The Function And Expression Of Bk Channels In Vascular Smooth Muscle Through Membrane And Nuclear Signals, Shinichi Asano

Graduate Theses, Dissertations, and Problem Reports (ETD)

Bisphenol A (BPA) exposure has recently become a public health concern, and the safety of the utilization of BPA has attracted the attention of the scientific community, politicians, and the general population. Although BPA is banned from baby products in a few countries because infants and young children are particularly susceptible to endocrine disruption, recent studies have consistently indicated the association between urinary BPA concentration and cardiovascular diseases in adults. Therefore, adult exposure to this xenoestrogen is becoming a healthcare issue that cannot be ignored. We selected large conductance Ca2+/voltage sensitive potassium (BK) channels as one of the target proteins …

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The Role Of Clustered Organization And Generation Of Mixed Properties In Macaque V2, Clinton Garret Cooper May 2012

The Role Of Clustered Organization And Generation Of Mixed Properties In Macaque V2, Clinton Garret Cooper

Graduate Theses, Dissertations, and Problem Reports (ETD)

Throughout the mammalian cortex, neurons of similar response characteristics group together into topographic functional domains. The genesis and role of this organization remains in question, but it has been proposed to affect the mixed properties of neurons. These types of neurons possess multiple receptive field preferences, such as a cell responding to a color and an oriented stimulus. To examine the functionality of clustered organization and their effect in generation of neurons possessing mixed properties, this dissertation examined the secondary visual cortex (V2) of the Macaca fasicularis. This particular cortex is comprised of domains organized according to distinct visual stimulus …

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Mass Spectrometric Approaches To Characterization Of Chemical Species Containing Metallic Ions, Guodong Gu May 2012

Mass Spectrometric Approaches To Characterization Of Chemical Species Containing Metallic Ions, Guodong Gu

Graduate Theses, Dissertations, and Problem Reports (ETD)

Mass spectrometry is a widely used analytical technique for both qualitative and quantitative analysis of physical, chemical, and biological compounds by measuring mass to charge ratio (m/z) of particles. It can supply elemental composition, molecular weight, and structure information of chemical compounds. The high sensitivity and analysis speed enable it to be an outstanding tool for chemical analysis. A Quadrupole Ion Trap Mass Spectrometry (QITMS) and a pulsed Glow Discharge Time-of-Flight Mass Spectrometry (GD-TOFMS) are employed in this study.;Internal energy distribution, P(E), of collision induced dissociation in QITMS is studied by using "thermometer molecules", whose fragmentation pathway consists of several …

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