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Errant Romanticism: Queering Gender And Sexuality In British Literature, 1790-1840, Teresa M. Pershing Jan 2016

Errant Romanticism: Queering Gender And Sexuality In British Literature, 1790-1840, Teresa M. Pershing

Graduate Theses, Dissertations, and Problem Reports (ETD)

Error is both a purposeless wandering and a purposeful identification of a mistake. Each chapter analyzes texts from the late-eighteenth and early-nineteenth centuries which feature female characters and the epilogue turns to the autobiographical writing of a man in the 21st-century. Chapters on William Godwin's memoirs of Mary Wollstonecraft, Amelia Alderson Opie's Dangers of Coquetry , Anne Plumptre's Something New, Harriet Martineau's Illustrations of Political Economy, and Thomas Beatie's autography Labor of Love feature characters---both real and fictional--- who destabilize what Bourdieu calls "collective[ly] misrecogn[ized]" understandings of identity as truth/error and "either/or." Utilizing notions of error developed by Zachary Sng …

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Grainyhead-Like-2 Inhibits The Co-Activator P300, Suppressing Tubulogenesis And The Epithelial-Mesenchymal Transition, Phillip M. Pifer Jan 2016

Grainyhead-Like-2 Inhibits The Co-Activator P300, Suppressing Tubulogenesis And The Epithelial-Mesenchymal Transition, Phillip M. Pifer

Graduate Theses, Dissertations, and Problem Reports (ETD)

Tumor progression and developmental morphogenesis require transient or stable Epithelial-Mesenchymal transitions (EMT) to modulate epithelial junctional complexes allowing programmed migration, invasion, and anoikis resistance of cells. Grainyhead-like-2 (GRHL2), an epithelial master-regulatory transcription factor, suppresses EMT and causes a mesenchymal-epithelial transition to the default epithelial phenotype. This body of work investigates the role of GRHL2 in kidney cancer, in kidney development using a kidney specific GRHL2 knockout mouse model, and in tubulogenesis using Madin-Darby Canine Kidney (MDCK) cells. In kidney cancer, GRHL2 was not expressed in the normal kidney proximal tubule epithelial cells which are thought to be the progenitors of …

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The Role Of Art Education In The K-12 Curriculum In West Virginia A Comparative Case Study Using Ethnographic Methods, Helen G. Poffenbarger-Jordan Jan 2016

The Role Of Art Education In The K-12 Curriculum In West Virginia A Comparative Case Study Using Ethnographic Methods, Helen G. Poffenbarger-Jordan

Graduate Theses, Dissertations, and Problem Reports (ETD)

The visual arts are considered a core subject in the United States public school curriculum. However, the way in which visual arts curriculum is implemented in schools is largely left up to the individual states. This study focused on how art educators' design, direct, find support, and operate visual arts programs in the K-12 public school system in West Virginia. Ethnographic research methods were implemented for this study.

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Comprehensive Analysis Of The Atlantic Coast Natural Gas Transmission Line, William David Young Jan 2016

Comprehensive Analysis Of The Atlantic Coast Natural Gas Transmission Line, William David Young

Graduate Theses, Dissertations, and Problem Reports (ETD)

New energy sources are needed to sustain our constant need for energy as well as the development of the next generation. The Atlantic Coast Pipeline is over 600 miles in length and will provide consistent, clean energy to the energy consumers in Virginia and North Carolina from natural gas production in the states of West Virginia, Pennsylvania, and Ohio. A detailed analysis was performed looking at modern pipeline construction as well as multiple studies to determine the economic, social, and environmental impacts of this transmission line. A theoretical study was also performed comparing how this transmission line would impact the …

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Load Testing And Recommended Repairs For Dailey Branch Bridges - Milepost 1.4 To 5.8, Luis Carlos Parra-Luckert Jan 2016

Load Testing And Recommended Repairs For Dailey Branch Bridges - Milepost 1.4 To 5.8, Luis Carlos Parra-Luckert

Graduate Theses, Dissertations, and Problem Reports (ETD)

The West Virginia Department of Transportation State Rail Authority sponsored a study to evaluate the condition of the railroad bridges on the Dailey Branch in Elkins, WV. The evaluations included field inspections, load rating, load testing, and a repair plan. A total of 2 steel bridges and 3 timber bridges were part of the study. The repair plan focused on identifying deteriorated timber bridge members for potential Glass Fiber Reinforced Polymer (GFRP) wrap repair. Information on dimensions and deterioration was gathered through field inspections. A timber specialist determined the species and grade of the timber bridges, finding most members to …

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A Radiological Survey Of Two Bruker D8 Advance Xrd Instruments Located In Separate Quality Control Laboratories, Justin Anthony Meador Jan 2016

A Radiological Survey Of Two Bruker D8 Advance Xrd Instruments Located In Separate Quality Control Laboratories, Justin Anthony Meador

Graduate Theses, Dissertations, and Problem Reports (ETD)

A Radiological Survey of Two Bruker D8 Advance XRD Instruments Located in Separate Quality Control Laboratories By Justin Meador In October 2016, XYZ Laboratories requested assistance with conducting a radiological survey of each of their Bruker D8 Advance XRD instruments to determine compliance with Title 64 West Virginia Legislative Rule, Department of Health, Series 23, Radiological Health Rules (64CSR23) and 10 CFR Part 20 – Standards for Protection Against Radiation in regards to the X-Ray radiation being emitted during operation of the units. A review of ionizing radiation, sources of radiation, biological effects, unit descriptions, Federal and State standards, description …

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Evaluating The Performance Of A Large-Scale Facial Image Dataset Using Agglomerated Match Score Statistics, Mounica Kamireddy Jan 2016

Evaluating The Performance Of A Large-Scale Facial Image Dataset Using Agglomerated Match Score Statistics, Mounica Kamireddy

Graduate Theses, Dissertations, and Problem Reports (ETD)

Biometrics systems are experiencing wide-spread usage in identification and access control applications. To estimate the performance of any biometric systems, their characteristics need to be analyzed to make concrete conclusions for real time usage. Performance testing of hardware or software components of either custom or state-of-the-art commercial biometric systems is typically carried out on large datasets. Several public and private datasets are used in current biometric research. West Virginia University has completed several large scale multimodal biometric data collection with an aim to create research datasets that can be used by disciplines concerning secured biometric applications. However, the demographic and …

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Voluntary Wheel Running Improves Recovery From Muscle Disuse In Mice, Matthew J. Brooks Jan 2016

Voluntary Wheel Running Improves Recovery From Muscle Disuse In Mice, Matthew J. Brooks

Graduate Theses, Dissertations, and Problem Reports (ETD)

The reloading of atrophied muscles from weightlessness or disuse results in injury and prolonged recovery. Satellite cells, or muscle stem cells, have a key role in facilitating injury-induced muscle repair but have not been shown to be required in muscle remodeling following atrophy. However, it has been less clear if low-impact exercise, such as voluntary wheel running, could provide a sufficient stimulus to enhance muscle recovery from atrophy through satellite cell activation. This study aimed to determine if voluntary wheel running improved recovery from muscle disuse following hindlimb suspension unloading (HSU), and if the recovery was associated with exercise-induced satellite …

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Cholesterol Diet-Associated Changes In The Hippocampus - A Prelude To Alzheimer's Disease?, Sylwia W. Brooks Jan 2016

Cholesterol Diet-Associated Changes In The Hippocampus - A Prelude To Alzheimer's Disease?, Sylwia W. Brooks

Graduate Theses, Dissertations, and Problem Reports (ETD)

High serum cholesterol levels in midlife have been associated with an increased risk of developing Alzheimer's disease (AD) later in life. This thesis investigates a possible mechanism linking dietary cholesterol, which cannot pass the blood brain barrier, and AD-like hippocampal neuropathology. The first study tested the hypothesis that a high cholesterol diet increases the flux of the cholesterol metabolite 27-hydroxycholesterol (27-OHC) into the hippocampus. We found that a high-cholesterol diet increased levels of 27-OHC, a biologically active circulatory breakdown product of cholesterol, in hippocampal tissue. 27-OHC has been identified as an endogenous selective estrogen receptor modulator (SERM) that affects estrogen …

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Conversion To Evangelical Christianity During College: An Interpretative Phenomenological Analysis, Meagan Alicia Brunson Jan 2016

Conversion To Evangelical Christianity During College: An Interpretative Phenomenological Analysis, Meagan Alicia Brunson

Graduate Theses, Dissertations, and Problem Reports (ETD)

Psychology has a history of ignoring and pathologizing spiritual experiences. Many of the fathers of early psychology including Freud, Ellis, and Skinner modeled this trend. However, with the increasing awareness of the importance of multicultural factors as they relate to mental health, religion and spirituality have gained recognition in the professional literature. Research on religion and spirituality and college students has mainly consisted of survey studies collecting demographic data. The current study uses a qualitative research design to explore the experiences of college students who converted to Christianity during college. The guiding questions of this research pertain mainly to the …

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Direct Inhibition Of Histamine Receptors In The Antennal Lobe Of Manduca Sexta: Putative Evidence For An Olfactory Corollary Discharge Circuit, Rex Burkland Jan 2016

Direct Inhibition Of Histamine Receptors In The Antennal Lobe Of Manduca Sexta: Putative Evidence For An Olfactory Corollary Discharge Circuit, Rex Burkland

Graduate Theses, Dissertations, and Problem Reports (ETD)

Animals that plume track have developed navigational strategies that optimize the ability to track an odor to its source. This movement is an active part of the olfactory experience. For vertebrates, sniffing is also an active part of the olfactory experience that controls the speed and regularity of odor interactions with the olfactory receptors. This sniffing is coincident with locomotion throughout the environment and head movement back and forth across an odor plume. Similarly, moths actively beat their wings as they encounter odor plumes. In Manduca sexta, this wing beating influences speed and regularity of olfactory input in such a …

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Application Of 1,2,3-Triazole In Gold Catalysis And Photoredox Catalysis, Rong Cai Jan 2016

Application Of 1,2,3-Triazole In Gold Catalysis And Photoredox Catalysis, Rong Cai

Graduate Theses, Dissertations, and Problem Reports (ETD)

Homogeneous gold catalysis has envisioned a rapid development during the past decade due to the remarkable efficiency of Au(I) in alkyne and allene activation. Air and thermally stable triazapentalene zwitterionic compounds (TAPZ) were prepared through Au(I)-catalyzed triazole-alkyne 5-endo-dig cyclization. While effective gold catalyst turnover was achieved, the stability of these new 10-pi-electron bicyclic structures was also significantly improved through the introduction of electron-withdrawing groups, which allowed the further application of these fluorescent dyes in cell imaging.;Silver salts are generally used for the activation of LAuCl through Cl - removal, and they are assumed to be innocent in Au(I) catalysis. For …

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Supplementing Art Therapy With Cognitive Behavioral Therapy (Cbt) And Dialectical Behavior Therapy (Dbt) During Treatment Of Childhood Anxiety Disorders: A Pilot Study, Rachel Cecil Jan 2016

Supplementing Art Therapy With Cognitive Behavioral Therapy (Cbt) And Dialectical Behavior Therapy (Dbt) During Treatment Of Childhood Anxiety Disorders: A Pilot Study, Rachel Cecil

Graduate Theses, Dissertations, and Problem Reports (ETD)

A qualitative research study presents a thorough examination of one therapist's methods of supplementing art therapy with cognitive behavioral therapy (CBT) and dialectical behavior therapy (DBT) during the treatment of children impaired by a variety of anxiety disorders---i.e. generalized anxiety disorder (GAD), obsessive-compulsive disorder (OCD), and posttraumatic stress disorder (PSTD). A review of the existing literature was used to inform the current study. The researcher created an exploratory case study, through the utilization of a pilot study, to gain a better understanding of the topic from an expert in these therapeutic fields. Through the gathering of data and analysis, the …

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Ecological Effects Of Forest Canopy Disturbance On The Understory Plant, American Ginseng (Panax Quinquefolius L.), Jennifer L. Chandler Jan 2016

Ecological Effects Of Forest Canopy Disturbance On The Understory Plant, American Ginseng (Panax Quinquefolius L.), Jennifer L. Chandler

Graduate Theses, Dissertations, and Problem Reports (ETD)

Historical accounts suggest that American ginseng was once far more abundant than it is today, and extensive changes in forest canopy structure and ginseng habitat caused by clearcut timber harvest occurred coincidentally to the precipitous decline in abundance. The presence of natural American ginseng populations after widespread clearcuts suggests that ginseng can survive under sparse canopies, and the presence of ginseng in the second growth forests common today suggest that ginseng can survive under dense canopies. However, performance may not be optimal at either end of the disturbance spectrum, and the net effect of direct and indirect anthropogenic canopy disturbances …

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Physicochemical Modulation Of Huntingtin Aggregation On Lipid Membranes: Implications For Huntington's Disease, Maxmore Chaibva Jan 2016

Physicochemical Modulation Of Huntingtin Aggregation On Lipid Membranes: Implications For Huntington's Disease, Maxmore Chaibva

Graduate Theses, Dissertations, and Problem Reports (ETD)

Huntington disease is a genetic, neurodegenerative disease caused by an expanded polyglutamine (polyQ) in the first exon of the huntingtin (htt) protein, facilitating its aggregation, leading to the formation of a diverse population of potentially toxic aggregate species, such as oligomers, fibrils, and annular aggregates. Htt interacts with a variety of membranous structures within the cell, and the first seventeen amino acids (Nt17) of htt directly flanking the polyQ domain is an amphipathic alpha-helix (AH) lipid-binding domain. AHs are also known to detect membrane curvature. Nt17 also promotes diverse aggregate species of htt and undergoes a number of posttranslational modifications …

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Comparative Analysis Of Uninhibited And Constrained Avian Wing Aerodynamics, Jordan A. Cox Jan 2016

Comparative Analysis Of Uninhibited And Constrained Avian Wing Aerodynamics, Jordan A. Cox

Graduate Theses, Dissertations, and Problem Reports (ETD)

The flight of birds has intrigued and motivated man for many years. Bird flight served as the primary inspiration of flying machines developed by Leonardo Da Vinci, Otto Lilienthal, and even the Wright brothers. Avian flight has once again drawn the attention of the scientific community as unmanned aerial vehicles (UAV) are not only becoming more popular, but smaller. Birds are once again influencing the designs of aircraft. Small UAVs operating within flight conditions and low Reynolds numbers common to birds are not yet capable of the high levels of control and agility that birds display with ease. Many researchers …

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Endocannabinoid Modulation Of Secretory And Inflammatory Causes Of Gastric Pathology, Molly S. Crowe Jan 2016

Endocannabinoid Modulation Of Secretory And Inflammatory Causes Of Gastric Pathology, Molly S. Crowe

Graduate Theses, Dissertations, and Problem Reports (ETD)

Non-steroidal anti-inflammatory drugs (NSAIDs) are common analgesic drugs that also cause well-known, negative gastrointestinal (GI) side effects. The specific physiological mechanism(s) of NSAID-induced GI damage are unknown, and are likely due to multiple causes. The most studied components include: increased gastric acid secretions, inflammation of the gastric epithelium, and increased gastric motility. Currently, proton pump inhibitor (PPI) antacids are used by chronic NSAID users, with the expectation that decreasing gastric acid output will reduce gastric epithelial irritation. However, PPIs are associated with side effects like infection, gastric polyps, and dementia. Therefore, new gastroprotective treatments that prevent NSAID-induced gastropathy are needed. …

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Young Adult Daughters And Their Parents: Communication About Workcareer And Family, Rita Daniels Jan 2016

Young Adult Daughters And Their Parents: Communication About Workcareer And Family, Rita Daniels

Graduate Theses, Dissertations, and Problem Reports (ETD)

Employing adult daughters' (N = 254) perspectives of their communication, relational quality, and identities with and surrounding their relationships with parents, I bridge organizational and family communication's scholarship realms to address family socialization regarding work/career and family. Specifically, I examine: (a) the content and context of memorable messages about work and/or family; (b) the connection between daughters' closeness to parents and daughters' likelihood to transmit these messages; and (c) the impact of mothers' socialization messages about work/career and family on daughters' personal, relational, and enacted identities (identity layers within the Communication Theory of Identity (CTI; Hecht (1993)). Using both online …

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Synergistic Modeling Of In-Vitro And In-Vivo Data Via Stochastic Kriging With Qualitative Factors (Skq), Behnam Dehghan Jan 2016

Synergistic Modeling Of In-Vitro And In-Vivo Data Via Stochastic Kriging With Qualitative Factors (Skq), Behnam Dehghan

Graduate Theses, Dissertations, and Problem Reports (ETD)

The objective of this study is to model in-vivo propranolol plasma concentration after administrating oral propranolol extended-release (ER) tablets. In-vivo data are typically expensive and scarce. To save time and cost needed to achieve high-quality in- vivo profile, this work utilizes both in-vitro and in-vivo data.;The ensemble of in-vitro and in-vivo data is modeled by stochastic kriging with qualitative factors (SKQ). It treats in-vivo and in-vitro as the two distinct levels of a qualitative factor. By synergistically modeling both types of data, SKQ is able to provide fitted in-vivo profiles whose quality is much higher than those obtained from modeling …

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Four Days That Transformed Spain 11-M Impact On Memory Recovery Examined Through The Lens Of Duality, Thomas J. Divins Jan 2016

Four Days That Transformed Spain 11-M Impact On Memory Recovery Examined Through The Lens Of Duality, Thomas J. Divins

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis studies the controversial aftermath of the Madrid terrorist attack of March 11, 2004 and how it impacted the history of memory and silence in Spain since the Spanish Civil War. The terrorist attack had surprising and significant short-term political impacts, which have been well documented by historians, political scientists, and journalists. However, surveying the attack aftermath through the lens of the history of duality in Spain has been less studied. The "lens of duality" is the viewpoint that Spain's history in the twentieth and twenty-first centuries can be explained as a clash between deeply-divided sectors within society which …

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Elucidating Mechanisms Of Canonical Wnt - Ephrin-B Crosstalk, William Tyler Koch Jan 2016

Elucidating Mechanisms Of Canonical Wnt - Ephrin-B Crosstalk, William Tyler Koch

Graduate Theses, Dissertations, and Problem Reports (ETD)

Throughout development, canonical Wnt signaling contributes to the formation and maintenance of a wide array of cells, tissues, and organs. Dys-regulated Wnt signaling during embryonic development is implicated in developmental defects known as neurochristopathies, including craniofacial and heart defects, as well as defects in neural development. Due to its roles in stem cell maintenance and self-renewal, tissue homeostasis, and regeneration, aberrant Wnt signaling in adult tissues can result in various forms of cancer, including colorectal cancer, breast cancer, lung cancer, and gastro-intestinal cancer, among others. Dys-regulated Wnt signaling is also implicated in other pathologies including bone disease, and metabolic diseases, …

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Assessment Of Molecular Action Of Direct Gating And Allosteric Modulatory Effects Of Meprobamate (Miltownrtm) On Gaba A Receptors, Manish Kumar Jan 2016

Assessment Of Molecular Action Of Direct Gating And Allosteric Modulatory Effects Of Meprobamate (Miltownrtm) On Gaba A Receptors, Manish Kumar

Graduate Theses, Dissertations, and Problem Reports (ETD)

Meprobamate (tradenames Miltown, Equanil) is a schedule IV anxiolytic and the primary metabolite of the muscle relaxant carisoprodol. Meprobamate modulates GABAA (gamma-aminobutyric acid type A) receptors, and has been described as having barbiturate-like activity. A thorough understanding of its mechanism remains ill-defined, however. To gain insight into its actions, we have conducted a series of studies using recombinant GABAA receptors. In alphaxbetazgamma2 GABAA receptors (where x = 1-6 and z = 1-3), the ability to enhance GABA-mediated current was evident for all alpha subunit isoforms, with the largest effect observed in alpha5-expressing receptors. Direct gating was comparable with all alpha …

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Development And Application Of Quantitative Gene Expression Assays In Wild-Caught, Non-Model Fish Species, Cassidy Megan Hahn Jan 2016

Development And Application Of Quantitative Gene Expression Assays In Wild-Caught, Non-Model Fish Species, Cassidy Megan Hahn

Graduate Theses, Dissertations, and Problem Reports (ETD)

The Great Lakes Basin is the most significant freshwater resource in North America. It is a central location for diverse anthropogenic enterprises and consequently has been heavily impacted by the release of toxic substances. Environmental studies increasingly identify the presence of both contaminants of emerging concern (CECs) and legacy contaminants in aquatic environments; however, the biological effects of these compounds on resident fishes remain largely unknown. To address this issue, the U.S. Fish and Wildlife Service Environmental Contaminants Programs initiated a multiagency, collaborative study which included chemical analysis of water and benthic sediment, assessment of caged fathead minnows and assessment …

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Distribution And Efficacy Of Chemotherapeutics In The Treatment Of Preclinical Brain Metastases Of Breast Cancer, Tori Terrell Hall Jan 2016

Distribution And Efficacy Of Chemotherapeutics In The Treatment Of Preclinical Brain Metastases Of Breast Cancer, Tori Terrell Hall

Graduate Theses, Dissertations, and Problem Reports (ETD)

Brain metastases are a critical, life-threatening problem for women with advanced metastatic breast cancer. Approximately 80% of women with disseminated central lesions are unable to survive the first year after diagnosis. Despite the breakdown of the blood-brain barrier, chemotherapeutics have limited penetration and distribution into brain metastases and are unable to induce cytotoxicity in the tumor. Limiting the development of new treatments for brain metastases of breast cancer, there are no commercially available in vitro models available that accurately model, and mimic the functionality of, the in vivo blood-tumor barrier (BTB). In an attempt to address the aforementioned problem, the …

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Modulation Of Coronary Reactive Hyperemia Through Soluble Epoxide Hydrolase: Role Of Oxylipins And Ppargamma, Ahmad Mahmoud Hanif Jan 2016

Modulation Of Coronary Reactive Hyperemia Through Soluble Epoxide Hydrolase: Role Of Oxylipins And Ppargamma, Ahmad Mahmoud Hanif

Graduate Theses, Dissertations, and Problem Reports (ETD)

Ischemic heart disease (IHD) continues to be a leading cause of morbidity and mortality in increasingly more countries. Function and structural damage to the heart are likely consequences of ischemic insults and may even lead to death. The body's physiological response to ischemia is by increasing nourishment or perfusion to the deprived organ in an attempt to decrease the potential ischemia-induced damage and achieve faster recovery. This reaction to ischemia is termed reactive hyperemia (RH), and in the heart, it is coronary reactive hyperemia (CRH). Epoxyeicosatrienoic acids (EETs) are oxylipins derived from arachidonic acid (AA) and possess distinct cardiovascular benefits, …

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The Influence Of Dams On Downstream Larval And Juvenile Fish And Benthic Macroinvertebrate Community Structure And Associated Physicochemical Variables, R. Daniel Hanks Jan 2016

The Influence Of Dams On Downstream Larval And Juvenile Fish And Benthic Macroinvertebrate Community Structure And Associated Physicochemical Variables, R. Daniel Hanks

Graduate Theses, Dissertations, and Problem Reports (ETD)

The Influence of Dams on Downstream Larval and Juvenile Fish and Benthic Macroinvertebrate Community Structure and Associated Physicochemical Variables R. Daniel Hanks The influence of dams on downstream biotic and abiotic components of aquatic ecosystems has been largely studied within the context of the River Continuum (RCC) and Serial Discontinuity Concepts (SDC). Few of these studies have sufficiently studied how these variables change along the longitudinal gradient below the impoundments in a systematic manner, comparing equal distances below both epilimnetic and hypolimnetic dams to a reference condition. This is especially true of early life stages of fish (i.e., larval and …

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The Effect Of Chemotherapy On Stromal Components Of The Bone Marrow, Ian Woodrow Hare Jan 2016

The Effect Of Chemotherapy On Stromal Components Of The Bone Marrow, Ian Woodrow Hare

Graduate Theses, Dissertations, and Problem Reports (ETD)

The cells comprising the stromal compartment of the bone marrow microenvironment are critical to the maintenance of several homeostatic processes of the body. For example, mesenchymal stem cells (MSCs) and osteoblasts are vital to the regulation of differentiation and quiescence of hematopoietic cells, maintaining the skeletal system, and regulating tumor microenvironments. In addition to contributing to these processes, MSCs display several properties that make them favorable for the use in transplantation therapies. The work described herein summarizes the means by which chemotherapy damages these cells, and potential consequences of such damage with regard to their function.;Previously, our laboratory has investigated …

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Spatial Redistribution Of Organic Phosphorus In Hay And Grass Pastures Of Eastern West Virginia Following Longterm Animal Manure Applications, Michael B. Harman Jan 2016

Spatial Redistribution Of Organic Phosphorus In Hay And Grass Pastures Of Eastern West Virginia Following Longterm Animal Manure Applications, Michael B. Harman

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study was conceived to investigate the fate of organic P (Po) in typical hay and grass pasture of eastern West Virginia. It is not uncommon in this region of West Virginia for hay and grass pastures to receive annual applications of animal manure, often on a nitrogen basis. As P management has evolved, many farms in the region have begun to use management tools such as a P index to continue use of animal manure as N fertilizer. However, many hay and grass pastures in the region already have a high degree of P saturation. There are reasonable expectations …

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The Relationship Between Plasma Osmolarity And Feed Efficiency In Beef Cattle And Effect Of Feeding Cows Medicated Feed Through Mineral Containing Altosidrtm Igr On The Growth Of Beef Calves, Taylor Diane Harrison Jan 2016

The Relationship Between Plasma Osmolarity And Feed Efficiency In Beef Cattle And Effect Of Feeding Cows Medicated Feed Through Mineral Containing Altosidrtm Igr On The Growth Of Beef Calves, Taylor Diane Harrison

Graduate Theses, Dissertations, and Problem Reports (ETD)

Dietary cation-anion modification in cattle has effects on productivity through various means. Alterations of dietary cation-anion balances has been shown to affect plasma osmolarity. Plasma osmolarity is directly related to renal function and metabolism in all animals. In a feeding operation with a single diet fed to a similar population of animals, plasma osmolarity should fall within a somewhat normal range (approximately 270-310 mOsm). However, subtle, yet very distinguishable differences will exist between animals. In theory, variances in osmolarity may reflect differences in metabolism and as such, efficiency of feed utilization. Many researchers believe that utilizing residual feed intake (RFI) …

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Molecular Characterization Of Lhx8, An Oocyte-Specific Transcription Factor, And Its Interacting Proteins In Rainbow Trout And Cattle, Liyuan Fu Jan 2016

Molecular Characterization Of Lhx8, An Oocyte-Specific Transcription Factor, And Its Interacting Proteins In Rainbow Trout And Cattle, Liyuan Fu

Graduate Theses, Dissertations, and Problem Reports (ETD)

LIM homeobox 8 (Lhx8) is an important transcription factor that is preferentially expressed in germ cells. Lhx8 null mice are infertile due to lack of oocytes and impairment of the transition from primordial follicles to primary follicles. Lhx8 deficiency also affects the expression of many important oocyte-specific genes. To date, no attempts have been made to investigate the existence of any cellular factors that might interact with Lhx8 protein in oocytes and early embryos. In this study, we report the characterization of rainbow trout and bovine Lhx8 genes and identification of important germ cell-specific nuclear factors that interact with Lhx8 …

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