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Articles 1081 - 1110 of 3669
Full-Text Articles in Entire DC Network
Application Of Molecular Pathology Techniques To Understand Mechanisms Of Disease In Smallmouth Bass, Heather Leigh Walsh
Application Of Molecular Pathology Techniques To Understand Mechanisms Of Disease In Smallmouth Bass, Heather Leigh Walsh
Graduate Theses, Dissertations, and Problem Reports (ETD)
In the Chesapeake Bay drainage, smallmouth bass Micropterus dolomieu are used as an indicator species of estrogenic contaminant exposure and have been implicated in fish kills and disease since 2005. In the Potomac River drainage, adult smallmouth bass have experienced mortality and disease and males have a high prevalence of intersex (testicular oocytes). Conversely, in the Susquehanna River drainage mortalities and disease of young-of-the-year smallmouth bass (YOY SMB) have occurred and resulted in a population shift to older and larger fish. The exact cause of these events remains unknown; however, factors such as poor water quality, contaminants, pathogens and parasites, …
The Integration Of Extrinsic And Intrinsic Neuromodulators In The Olfactory System, Kristyn M. Lizbinski
The Integration Of Extrinsic And Intrinsic Neuromodulators In The Olfactory System, Kristyn M. Lizbinski
Graduate Theses, Dissertations, and Problem Reports (ETD)
Neuromodulation is a ubiquitous feature of neural systems, allowing flexible, context specific control over network dynamics by adjusting the biophysical and synaptic properties of neurons. Neuromodulation was first described in invertebrate motor systems and early work established a basic dichotomy for neuromodulation as having either an intrinsic origin (i.e. neurons that participate in network coding) or an extrinsic origin (i.e. neurons from independent networks). Although this dichotomy has been thoroughly considered in motor systems, it has received far less attention in sensory systems. Furthermore, nervous systems are continually subject to a dynamic cocktail of both intrinsic and extrinsic modulators. However, …
Syntheses Of Azepinoindole Alkaloids Cimitrypazepine, Fargesine And Hyrtioreticulins C & D, Ganesh Ghimire
Syntheses Of Azepinoindole Alkaloids Cimitrypazepine, Fargesine And Hyrtioreticulins C & D, Ganesh Ghimire
Graduate Theses, Dissertations, and Problem Reports (ETD)
The Watanabe-Cenini-Söderberg reductive N-heterocyclization has emerged as a powerful tool for the synthesis of a variety of functionalized indoles. Söderberg’s elaboration of this methodology has been utilized as a late-stage cyclization protocol for the synthesis of azepinoindole alkaloids, a class of natural products characterized by an azepane skeleton fused with an indole ring. Short syntheses of the naturally occurring azepino[5,4,3-cd]indole alkaloids, cimitrypazepine, fargesine, and the diastereomeric hyrtioreticulins C & D have been completed starting from commercially available tetra-substituted benzene derivatives. The key azepinoindole core in each case was assembled via an intramolecular Mizoroki-Heck reaction followed by a …
An Examination Of Cyanotoxins And Environmental Estrogens In The Middle And Upper Potomac River Watershed, Usa, Ryan Patrick Braham
An Examination Of Cyanotoxins And Environmental Estrogens In The Middle And Upper Potomac River Watershed, Usa, Ryan Patrick Braham
Graduate Theses, Dissertations, and Problem Reports (ETD)
The Potomac River is a large tributary of the Chesapeake Bay. Large fish die-offs were reported in the Potomac watershed (specifically the South Branch of the Potomac) in 2002 and 2005, as well as smaller episodic events in recent years which have no clear correlation to any one pathogen or contaminant. Although a variety of pathogens have been identified (such as trematodes, myxozoans, Aeromonas hydrophila, A. salmonicida, Flavobacterium columnare , and largemouth bass virus) in recent die-offs of smallmouth bass Micropterus dolomieu, no clear cause has been derived. Additionally, reproductive endpoints were reported in smallmouth bass and likely associated with …
Identifying The Esthetically Optimal Ap Position Of Maxillary Incisors In Caucasian Females, Mackenzie Boyles-Horan
Identifying The Esthetically Optimal Ap Position Of Maxillary Incisors In Caucasian Females, Mackenzie Boyles-Horan
Graduate Theses, Dissertations, and Problem Reports (ETD)
Background and Objectives: The majority of orthodontists routinely evaluate the amount of maxillary incisor display from a frontal perspective, however they do not regularly evaluate a patient's smiling profile with the teeth visible when diagnosing and treatment planning. This study uses the facial plane Glabella Vertical, a vertical line tangent to the subject's soft glabella, to classify the maxilla's AP position. The purpose of this study is to determine if there is a difference in perceived attractiveness between smiling and repose facial profiles and to identify if there is an esthetically optimal AP position of the maxillary incisors in Caucasian …
The Role Of Interleukin-12 And Exosomes In The Dynamic Interplay Of Cancer And The Immune System, Christina Nicole Nikki Byrne-Hoffman
The Role Of Interleukin-12 And Exosomes In The Dynamic Interplay Of Cancer And The Immune System, Christina Nicole Nikki Byrne-Hoffman
Graduate Theses, Dissertations, and Problem Reports (ETD)
Melanoma and breast cancers account for a large number of cancer diagnoses and deaths, with 1 in 28 and 1 in 8 developing melanoma or breast cancer, respectively, in their lifetime. T Lymphocytes play a pivotal role in the immune system response to cancers and are known to evade the immune system by a variety of mechanisms, including modulation of cytokine function. A cytokine important for the function of T lymphocytes, Interleukin-12, and modulation of its Janus Kinase and activators of transcription (JAK-STAT) signaling pathway, plays a role in the immune response to tumors, especially melanoma. We examined the role …
Impact Of A Fruit And Vegetable Diet Intervention In Young Adults With Metabolic Syndrome On Behavior And Gut Microbiome, Rashel L. Clark
Impact Of A Fruit And Vegetable Diet Intervention In Young Adults With Metabolic Syndrome On Behavior And Gut Microbiome, Rashel L. Clark
Graduate Theses, Dissertations, and Problem Reports (ETD)
Background: Metabolic Syndrome (MetS) is a clustering of factors that increases the risk of developing cardiovascular diseases and diabetes. The rates of MetS are on the rise, even among young adults. The primary objective of the Fruvedomics phase 2 study was to determine changes in behavior, cardiovascular, and gut microbiome health in a group of young adults with MetS following an 8-week, free-living, dietary intervention.;Methods: The dietary intervention followed the USDA Dietary Guidelines for Americans and focused on increasing fruit and vegetable intake to equal half their diet. University students (18--30 years old) with MetS were recruited on the West …
Pilot Testing Of A Geomorphic Landform Design Reclamation Using A Vegetative Layer With Short Paper Fiber Amendment On An Abandoned Coal Refuse Pile In Appalachia, Levi Cyphers
Graduate Theses, Dissertations, and Problem Reports (ETD)
Over 3,000 abandoned mine lands in the Appalachian regions of West Virginia, Pennsylvania, and Kentucky and are in need of reclamation. This research tested an alternative cap and cover reclamation design using short paper fiber as a soil amendment in a coarse coal refuse vegetation layer. Short paper fiber is the solid residuals extracted from the paper manufacturing process, and treated as waste. Short paper fiber is a nutrient dense material that has been successfully tested as a soil amendment in soils. The intent of the vegetation layer was to support grass growth and persistence, stabilize the site, and reduce …
Prediction Of Thrombus Formation In Ladder Network And Stability Of Thrombus In A Bifurcation, Hari Hara Sudhan Lakshmanan
Prediction Of Thrombus Formation In Ladder Network And Stability Of Thrombus In A Bifurcation, Hari Hara Sudhan Lakshmanan
Graduate Theses, Dissertations, and Problem Reports (ETD)
Thrombus formation on complex branched networks like extracorporeal membrane oxygenators (ECMO) is poorly understood. In this work, we built a COMSOL model on branched networks, to understand and predict the thrombus formation under blood flow. A microfluidic ladder network design was used to study the change in hemodynamics. The microfluidic ladder sizes are chosen to mimic the physiologically relevant shear rates of 300 s--1 and 700 s--1 in main channels and bypasses respectively. The COMSOL model results were analyzed to understand the flow dynamics inside the ladder network. We predicted the thrombus nucleation points in the ladder network, based on …
Applications Of Artificial Intelligence (Ai) In Petroleum Engineering Problems, Shan E Zehra Lashari
Applications Of Artificial Intelligence (Ai) In Petroleum Engineering Problems, Shan E Zehra Lashari
Graduate Theses, Dissertations, and Problem Reports (ETD)
For the last few decades multiple business sectors have been influenced by the advancement in Artificial Intelligence (AI). Though the oil and gas sector began to utilize the potential of AI comparatively latter than many other sectors, the appreciable amount of work has been done by researchers to equip the industry with AI tools. This work aims to explore various horizons of petroleum engineering by using different AI tools.;For providing better decision making in reservoir fluid characterization problem, fuzzy logic has been applied, which is an AI method to drive decisions when data is incomplete or unreliable. The second part …
Characterization Of Kndy Neuronal Activity In Gilts: Distribution And Effect Of A Progestin, Ashley Nicollette Lindo
Characterization Of Kndy Neuronal Activity In Gilts: Distribution And Effect Of A Progestin, Ashley Nicollette Lindo
Graduate Theses, Dissertations, and Problem Reports (ETD)
Puberty is a process that incorporates a large array of both external factors and internal signals. The endocrinology of puberty has been studied in a number of mammalian species and typically depends upon an increase in hypothalamic secretion of gonadotropin releasing hormone (GnRH). Neural inputs regulating GnRH secretion during the pubertal process are not completely understood. In the past decade, attention has focused on the role for a particular set of neurons located in the arcuate nucleus (ARC) of the hypothalamus. They have been named KNDy neurons because they coexpress kisspeptin, neurokinin B (NKB) and dynorphin and have been shown …
A Low-Cost Normalized Difference Vegetation Index (Ndvi) Payload For Cubesats And Unmanned Aerial Vehicles (Uavs), Steven Hard
A Low-Cost Normalized Difference Vegetation Index (Ndvi) Payload For Cubesats And Unmanned Aerial Vehicles (Uavs), Steven Hard
Graduate Theses, Dissertations, and Problem Reports (ETD)
The focus of this research has been the design and fabrication of a Normalized Difference Vegetation Index (NDVI) payload configuration. This unique payload employs low-cost commercial off-the-shelf (COTS) hardware and equipment to assess photosynthetic activity and vegetation health through remote sensing on Cubesat or Unmanned Aerial Vehicle (UAV) platforms. The proposed NDVI imaging payload is comprised of three main subsystems: an electrical system, a software system, and a hardware system. The electrical system includes a custom designed printed circuit board (PCB), a single cell 3.7 V lithium-polymer battery, voltage regulator circuitry components, and wiring harnesses and connectors. The software system …
Nanocellulose From The Appalachian Hardwood Forest And Its Potential Applications, Masoumeh Hassanzadeh
Nanocellulose From The Appalachian Hardwood Forest And Its Potential Applications, Masoumeh Hassanzadeh
Graduate Theses, Dissertations, and Problem Reports (ETD)
Nanofibrillated cellulose (NFCs) are nanoscale fibers of high aspect ratio that can be isolated from a wide variety of cellulosic sources, including wood and bacterial cellulose. With high strength despite of their low density, NFCs are a promising renewable building block for the preparation of nanostructured materials and composites. To fabricate NFC-based materials with improved mechanical and chemical properties and additional new functionalities for different applications, it is essential to tailor the surface properties of individual NFCs. The surface structures control the interactions between NFCs and ultimately dictate the structure and macroscale properties of the bulk material. This research was …
Behavior Of Stiff-Tailed Diving Ducks And West Indian Whistling Ducks In Laguna Cartagena National Wildlife Refuge, Puerto Rico, Nick S. Goodman
Behavior Of Stiff-Tailed Diving Ducks And West Indian Whistling Ducks In Laguna Cartagena National Wildlife Refuge, Puerto Rico, Nick S. Goodman
Graduate Theses, Dissertations, and Problem Reports (ETD)
Masked ducks (Nomonyx dominicus), migratory northern ruddy ducks (Oxyura jamaicensis jamaicensis), non-migratory West Indian ruddy ducks (Oxyura j. jamaicensis Gmelin), and West Indian whistling-ducks (Dendrocygna arborea) are all duck taxa that have declining populations in Puerto Rico. Masked ducks are listed as endangered in Puerto Rico and are a species of concern in the Caribbean while West Indian whistling ducks are considered an "at-risk" species listed as vulnerable. All 4 taxa of duck have areas of their life history where information is lacking including behavioral information. I studied the 4 taxa of duck at Laguna Cartagena National Wildlife Refuge from …
Late Victorian Sexuality And Spiritualism: The Place Of The Paranormal In Queer Erotic Partnerships, Sharon E. Kelly
Late Victorian Sexuality And Spiritualism: The Place Of The Paranormal In Queer Erotic Partnerships, Sharon E. Kelly
Graduate Theses, Dissertations, and Problem Reports (ETD)
This dissertation argues that fin de siecle navigations of emerging categories of sexual identity were partially expressed in literary representations of supernatural connections, transformations, events, and practices. I build on Sexuality Studies and Queer Theory foundations by such scholars as Foucault, Halberstam, and Warner along with New Historicist scholarship about spiritualism in the nineteenth century to examine the connections between aberrant erotic desires and alternative forms of spirituality. Through readings of the anonymous Teleny (1893), Wilde's The Picture of Dorian Gray, Richard Marsh's The Beetle , and the poetry of Michael Field, I assert that queer sexual identities and acts, …
Signal Fusion And Semantic Similarity Evaluation For Social Media Based Adverse Drug Event Detection, Hameeduddin Irfan Khaja
Signal Fusion And Semantic Similarity Evaluation For Social Media Based Adverse Drug Event Detection, Hameeduddin Irfan Khaja
Graduate Theses, Dissertations, and Problem Reports (ETD)
Recent advancements in pharmacovigilance tasks have shown the usage of social media as a resource to obtain real-time signals for drug surveillance. Researchers demonstrated a good potential for the detection of Adverse Drug Events (ADEs) using social media much earlier than the traditional reporting systems maintained by official regulatory authorities like the United States Food and Drug Administration (FDA). Existing automated drug surveillance systems have used various types of social media channels and search query logs for monitoring ADE signals.;In this thesis, we address two key performance issues related to automated drug surveillance systems. The first is to improve the …
Examination And Characterization Of Brook Trout Ecology Before And After A Broad Scale Disturbance Event In Headwater Streams Of West Virginia, Usa, Ross Gilbert Andrew
Examination And Characterization Of Brook Trout Ecology Before And After A Broad Scale Disturbance Event In Headwater Streams Of West Virginia, Usa, Ross Gilbert Andrew
Graduate Theses, Dissertations, and Problem Reports (ETD)
No abstract provided.
“To Meet Her, That Changed Everything”: Adult Adoptees’ Discursive Construction Of The Meaning Of “Parent” Following Birth Parent Contact, Christine K Anzur
“To Meet Her, That Changed Everything”: Adult Adoptees’ Discursive Construction Of The Meaning Of “Parent” Following Birth Parent Contact, Christine K Anzur
Graduate Theses, Dissertations, and Problem Reports (ETD)
No abstract provided.
Molecular Dynamics And Nonlinear Dynamics Studies Of Chemical Systems, Sadegh Faramarzi Ganj Abad
Molecular Dynamics And Nonlinear Dynamics Studies Of Chemical Systems, Sadegh Faramarzi Ganj Abad
Graduate Theses, Dissertations, and Problem Reports (ETD)
No abstract provided.
Biomimetic And Advanced Control Structure Design With Real Time Optimization, Temitayo Bankole
Biomimetic And Advanced Control Structure Design With Real Time Optimization, Temitayo Bankole
Graduate Theses, Dissertations, and Problem Reports (ETD)
No abstract provided.
A Corrollary Discharge Circuit Modulates Olfactory Function During Flight In Manduca Sexta, Phillip David Chapman
A Corrollary Discharge Circuit Modulates Olfactory Function During Flight In Manduca Sexta, Phillip David Chapman
Graduate Theses, Dissertations, and Problem Reports (ETD)
No abstract provided.
Exploring The Geosensory In Geography: Examining Olfaction And Geo-Virtual Immersion As Contributors To A Sense Of Place And Embodiment, Aaron Michael Ferrari
Exploring The Geosensory In Geography: Examining Olfaction And Geo-Virtual Immersion As Contributors To A Sense Of Place And Embodiment, Aaron Michael Ferrari
Graduate Theses, Dissertations, and Problem Reports (ETD)
No abstract provided.
Biophysical Investigation Of Phlip-Membrane Interaction, Chitrak Gupta
Biophysical Investigation Of Phlip-Membrane Interaction, Chitrak Gupta
Graduate Theses, Dissertations, and Problem Reports (ETD)
No abstract provided.
Exploring The Meaning Of Sustainability Within Three Selected Institutions Of The Graphic Design Field: A Phenomenological Study, Szilvia Kadas
Exploring The Meaning Of Sustainability Within Three Selected Institutions Of The Graphic Design Field: A Phenomenological Study, Szilvia Kadas
Graduate Theses, Dissertations, and Problem Reports (ETD)
No abstract provided.
Prescribed Defoliation Strategies Influence Soil Carbon Dynamics And Nitrous Oxide Emission Potential In West Virginia Pastures, Jordan M.A Koos
Prescribed Defoliation Strategies Influence Soil Carbon Dynamics And Nitrous Oxide Emission Potential In West Virginia Pastures, Jordan M.A Koos
Graduate Theses, Dissertations, and Problem Reports (ETD)
No abstract provided.
Exploring Memory Of Place And Place Identity Through Narrative Inquiry: A Study Of Partisans’ Square In Uzice, Serbia, Sofija Kaljevic
Exploring Memory Of Place And Place Identity Through Narrative Inquiry: A Study Of Partisans’ Square In Uzice, Serbia, Sofija Kaljevic
Graduate Theses, Dissertations, and Problem Reports (ETD)
No abstract provided.
Brownian Motion In Cellular Receptors, Ouri Maler
Brownian Motion In Cellular Receptors, Ouri Maler
Graduate Theses, Dissertations, and Problem Reports (ETD)
No abstract provided.
Reducing Spatial Stochastic Models Of Membrane Receptors To Approximately Equivalent Chemical Reaction Networks Through Coarse Graining, Christopher Short
Reducing Spatial Stochastic Models Of Membrane Receptors To Approximately Equivalent Chemical Reaction Networks Through Coarse Graining, Christopher Short
Graduate Theses, Dissertations, and Problem Reports (ETD)
Computational models are necessary for understanding how biological functionality emerges from a complex network of molecular interactions such as in cell signaling. Due to the complexity of biological systems, the normal scientific method of hypothesizing then testing predictions is becoming increasingly difficult. The large number of processes limits the level of modeling detail; signaling models typically adopt a non-spatial representation where each molecular process is characterized by a few parameters.;However, modern microscopic imaging of receptors on cell membranes reveals an intricate structure of microdomains. Receptors, such as epidermal growth factor receptor (EGFR), vascular endothelial growth factor receptor (VEGFR), and others, …
Potential Effects Of Oil And Natural Gas Development On Mule Deer (Odocoileus Hemionus) Survival And Fawn Rearing Resource Selection, Brett P. Skelly
Potential Effects Of Oil And Natural Gas Development On Mule Deer (Odocoileus Hemionus) Survival And Fawn Rearing Resource Selection, Brett P. Skelly
Graduate Theses, Dissertations, and Problem Reports (ETD)
A worldwide increasing demand for both renewable and non-renewable energy resources has been ongoing for the past 50 years and is projected to continually increase for the next two decades. The direct and indirect effects of oil and natural gas development are not quantified but may be playing an important role in mule deer population dynamics. For this project I: (1) evaluated the potential effects of oil and natural gas development on survival probabilities of mule deer and; (2) evaluated the potential effects of oil and natural gas development on fawn rearing resource selection. I assessed mule deer survival and …
Personality, Sleep, And Mortality, Shantel Spears
Personality, Sleep, And Mortality, Shantel Spears
Graduate Theses, Dissertations, and Problem Reports (ETD)
Personality traits and sleep are associated with health and longevity; however, no investigation has examined whether sleep is a pathway linking personality to mortality risk. Thus, we tested this effect across a 20-year mortality follow-up period in the Midlife Development in the United States (MIDUS) cohort (N = 3,253; M age = 47.03 years, SD = 12.39, range = 20-75), using proportional hazards in a structural equation modeling (SEM) framework. Openness was the only trait predictor of death risk. Daytime sleepiness and short and long sleep duration also emerged as predictors of mortality risk. We found indirect effects for neuroticism, …