Digital Commons Network^™

Development Of Machine Learning Algorithm To Identify High-Emitters From On-Road Data For Heavy-Duty (Hd) Vehicles, Filiz Kazan

Graduate Theses, Dissertations, and Problem Reports (ETD)

The process of on-road, heavy-duty engine family certification is regulated by the United States Environmental Protection Agency (US EPA). Currently, the US EPA 2010 emissions standards require the threshold from the Federal Testing Procedure (FTP) engine dynamometer cycle to be at or below a brake-specific NO_x (bs-NO_x) value of 0.20 g/bhp-hr for heavy-duty (HD) engines. The engine manufacturers are also required to conduct in-use portable emission measurement system (PEMS) testing to prove their products' compliance. The selected vehicles are required to satisfy not-to-exceed (NTE) analysis under normal driving conditions in the heavy-duty in-use testing (HDIUT) program. California …

Evaluate The Efficacy Of A Mixture Of Peroxyacetic Acid And H2o2 Against The Survival And Cross-Contamination Of The Salmonella Surrogate Enterococcus Faecium On Tomatoes During Triple-Wash, Corey Waitman Coe

Graduate Theses, Dissertations, and Problem Reports (ETD)

Triple-wash with a mixture of peroxyacetic acid and H2O2 (SaniDate-5.0) during post-harvest processing of fresh produce has been recommended by West Virginia Small Farm Center to improve microbial safety. It has been well recognized that the washing of produce is more important for preventing cross-contamination than reducing foodborne pathogens. Furthermore, it may help improve public confidence in that the produce they obtain from locally grown farmers is safe for their consumption. determine the efficacy of SaniDate-5.0 for reducing the survival and preventing cross-contamination of the Salmonella surrogate Enterococcus faecium on tomatoes during triple-wash.

E. faecium ATCC-8459 (resistant to 100-ppm nalidixic-acid) …

Mechanical Response Of Vartm Infused Frp Composites, Andrew Kenney

Graduate Theses, Dissertations, and Problem Reports (ETD)

Mechanical Response of VARTM based FRP composites

Andrew Kenney

The United States Department of Transportation (USDOT) recently created two new design specification for rail tank cars. These new types of classification, DOT-117 and DOT-117R, are designed with additional safety precautions to prevent hazardous chemicals from leaking out in case of a derailment. Features such as a thicker outer steel wall, head shield, and top and bottom valve protections provide additional protection compared to the current DOT-113 tank cars at the cost of additional weight. The WVU-CFC proposes a multifunctional, composite jacket that could be used in place of current tank …

Living On The Edge: Trans* Exclusion, Survival, And Resistance, Rayna E. Momen

Graduate Theses, Dissertations, and Problem Reports (ETD)

ABSTRACT

This dissertation focuses on the criminalization and victimization of transgender people, broadly defined as people whose gender identity does not align with their assigned birth sex, using a queer criminological and intersectional lens. The introduction offers background and context for this examination, and includes the purpose, theoretical approach, methodology, research questions, contributions, and overviews of the substantive chapters. Chapter two explores what we know and what we do not know about transgender people’s pathways into the criminal legal system, how they experience state surveillance, and how they navigate the system. Chapter three explores violence against transgender people in various …

The Impact Of Formation And Fracture Properties Alternations On The Productivity Of The Multi-Stage Fractured Marcellus Shale Horizontal Wells., Dalal Aldbayan

Graduate Theses, Dissertations, and Problem Reports (ETD)

As the reservoir deplete, the pore pressure decreases and the effective stress increases. The increase in the effective stress results in the formation compaction which can alter the formation and hydraulic fracture properties. This is particularly significant for a Marcellus shale horizontal well with multi-stage hydraulic fracture due to low Young's modulus and moderate Poisson's ratio of the Marcellus shale. The degree of the effective stress increase depends on the initial productivity of the well, which is influenced by the hydraulic fracture properties, formation properties, as well as the operating conditions. Therefore, it is necessary to couple the geomechanical and …

Evaluating Potential Soil Amendments And Geomorphic Methods For Mine Land Reclamation, Amanda Rodrigues Silva

Graduate Theses, Dissertations, and Problem Reports (ETD)

The United States has approximately 22% of the world’s coal reserves. Since 1961, the electric power sector has been the major user of coal in the U.S., accounting for 91.9% of the coal consumed in the country in 2021. Sixty-two percent of total U.S. coal production in 2021 was sourced from surface mining, and Wyoming, West Virginia, Pennsylvania, Illinois, and Montana were responsible for 74% of this total production.

Coal-mining activities expose sulfide minerals in rocks that, when in contact with oxidizing conditions, produce sulfate-rich drainage known as acid mine drainage (AMD). AMD treatment typically involves chemical treatments to raise …

An Action Research Evaluation Of An Online Inclusive Sport Peer Coach Training, Margaret Roberts Condon

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Trained peer tutors are a proven pedagogical technique that can help eliminate barriers to inclusion in physical education and extracurricular sport, including a reported lack of training and experience of professionals. When adequately trained, peer tutors can encourage social interactions, provide constant feedback, and increase active learning and engagement. While recommendations for training peer tutors have been provided, there are currently no known studies examining a peer tutor training in an online format for middle and high school-aged students participating in an inclusive sport program.

Purpose: The purpose of this study was to evaluate the effectiveness of an …

Bacterial Contamination In Public Atac-Seq Data And Alignment-Free Detection Methods, Drake Michael Aesoph

Graduate Theses, Dissertations, and Problem Reports (ETD)

ATAC-seq is a new high-throughput sequencing technology for measuring chromatin accessibility within genomic samples. It can be used to discover new information about open regions, nucleosome positions, transcription factor binding sites, and DNA methylation. It is especially useful when combined with other next-generation sequencing techniques, such as RNA-seq. Unlike previous technologies, however, ATAC-seq is more sensitive to bacterial contamination, which is a well-known problem in cell cultures that can lead to incorrect experimental results. Previous studies have measured the contamination in public RNA-seq data and found that 5%- 10% of samples were contaminated. In this report, we investigate the prevalence …

Tumor-Targeted Ph-Sensitive Manganese Oxide Nanoparticle For Enhanced Detection Of Breast Cancer Using Mri, Celia Martinez De La Torre

Graduate Theses, Dissertations, and Problem Reports (ETD)

In the United States, approximately 287,850 new cases of invasive breast cancer will be diagnosed, and over 43,000 women will die because of it in 2022. Currently, mammography is the gold standard for breast cancer surveillance. Although this detection technique is relatively cheap and fast, it misses about 1 in 5 breast cancers in younger women with dense breast tissue, causing a delay in treatment. Compared to mammography, magnetic resonance imaging (MRI) has superior soft-tissue contrast that elucidates structural differences within soft tissue to detect more breast cancers. However, MRI still misses

NEMO particles were produced by synthesizing manganese oxide …

The Business Of Behavior: Appalachian Teachers’ Experiences In Using Positive Behavior Interventions And Support, Erin Michele Coffield

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation explores the lived experiences of Appalachian elementary and middle school teachers who have been identified as working in Positive Behavior Intervention and Support (PBIS) schools. This study used Lifeworld Theory to engage in discussion about the teachers’ individual experiences in using PBIS in their classrooms in relation to resilience frameworks and childhood trauma. The teachers’ individual experiences were analyzed using a Whole-Part-Whole analysis to bring the individual stories together to better understand how PBIS and childhood trauma are experienced in a specific Appalachian school. Discussion opens up through the participants' experiences about grit models in school, trauma their …

First Responders’ Assumptions: An Exploration Of Emergency Medical Technicians’ Secondary Traumatic Stress And Perceptions Of Substance Users, Glenn Noble

Graduate Theses, Dissertations, and Problem Reports (ETD)

Emergency medical technicians (EMT) and firefighters respond to critical incidents and provide emergent care. As the opioid crisis continues and drug overdose rates increase, first responders administer first aid to substance users, including Naloxone, more frequently. This study examined the influence of repeated exposure to drug-related critical incidents and provision of care to substance users on EMTs' and firefighters' secondary traumatic stress (STS) level, world assumptions, and substance use stigma. First responders' world assumptions, STS, burnout, and exposure to drug-related overdoses were analyzed for their power in predicting substance use stigma. Results suggest that occupational burnout, rather than STS, is …

Mechanistic Insight Into Chronic Stress-Induced Cerebrovascular Dysfunction, Emily Nicole Burrage

Graduate Theses, Dissertations, and Problem Reports (ETD)

Despite decades of research psychological stress remains a prevalent problem in society, often diminishing quality of life and increasing the risk of developing dementia. The brain plays a central role in the response to stress and as it is unable to store energy substrates, the brain relies heavily on dynamically regulated blood flow. Therefore, it is important that there is a tight coupling between neural activity and cerebral blood flow to meet metabolic demands and maintain critical brain function. It has been established that chronic psychological stress has detrimental effects on cerebrovascular function, potentially through increased superoxide anion production through …

Mechanisms Of Nourishment, Raymond Lloyd Brown Iii

Graduate Theses, Dissertations, and Problem Reports (ETD)

This written thesis is a description and analysis of the ceramic work of Ray Brown. Included in this thesis is an explanation and defense of my work in my exhibition Mechanisms of Nourishment. It also unpacks the conceptual, technical, and formal aspects of the work.

The research explored in this written thesis discusses the relationship between the aesthetic and utilitarian components of pottery. From an analytical, iterative approach to form, I strive to isolate proportions that evoke a sense of volume and repetition. My references to Mid Century Modern and Streamlining Era design guide my efforts into dynamic mechanisms of …

Detection Of Fecal Bacteria In Watersheds Impacted By Acid Mine Drainage, Claire Addison Mcdonald

Graduate Theses, Dissertations, and Problem Reports (ETD)

Escherichia coli, a fecal coliform, is an essential component of water quality monitoring, entering waterways through sewage deposits, agricultural land and livestock, and wildlife. Various fast and user-friendly methods for quantifying E. coli make it the principal indicator bacteria for fecal contamination. The most common methods for E. coli quantification are culture-based and involve cultivating samples onto nutrient agar and counting the visible colonies. However, E. coli can enter a viable but non-culturable (VBNC) state in stressful environments. Bacteria in a VBNC state are still alive but reduce key metabolic activities that typically encourage growth and division, allowing them …

Global Engagement Model For Land-Grant Universities, A Grounded Theory., Lorena Ivonne Ballester

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study is to examine how land-grant universities engage with the public in the era of globalization; to explain the institutionalization of engagement processes accounting for the global context; and, to integrate this analysis into a Global Engagement Model for Land-Grant Universities (GEM) implementing a grounded theory research methodology.

GEM’s foundation is both theoretical and empirical. Applying the intensity sampling method, the universities selected for the empirical base were: The University of California, Davis, Michigan State University, and The Pennsylvania State University. Rather than an exact representation of individual universities’ engagement models, the model is the researcher’s …

Implementation Of A Nonverbal Scrub Cap Identification System To Improve Communication And Perception Of Patient Safety Among Unfamiliar, De-Identified Staff Members In The Operating Room., Keri Ann Roskowinski

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Operating room (OR), professionals deliver patient care with brief introductions, and roles were not always identified, and although team members wear identification (ID) badges, they were usually covered by sterile gowns and other routine personal protective equipment (PPE). Purpose: The aim of this Doctor of Nursing Practice (DNP) project was to determine if a simple intervention to apply the individual’s name and role to a scrub cap could improve identification, OR team communication, and consequently, patient safety. The participants in this project consisted of nurses, physicians, anesthesia providers, scrub technicians, students, medical sales representatives, and those that identified as …

Age As A Moderator Of Health Outcomes And Trust In Physicians And The Healthcare System, Emma Katz M.S.

Graduate Theses, Dissertations, and Problem Reports (ETD)

Trust is an integral part of the healthcare experience. Patient trust is associated with treatment adherence, patient satisfaction, patients engaging in follow-up care, shared decision-making, and positive health-related outcomes (e.g., Gupta et al., 2014; Mohseni & Lindstrom, 2007; Musa et al., 2009; Tam, 2012; Thom, et al., 2004; Trachtenberg et al., 2005). There are several levels of trust discussed in the literature, including interpersonal trust and institutional trust. The current study examined two levels of trust: interpersonal trust in the form of trust in the physician and institutional trust in the form of trust in the healthcare system. The study …

Imagined Communities: The British Planter In Nyasaland, 1890 - 1940, Benjamin Marnell

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis examines concepts of British settler identity and how it developed across trans-national bounds. Between the 19th and 20th centuries, the rise of industrialisation and developments in transportation, mass communication and print media fuelled a new wave of settler movements from Britain. As settlers spread to different continents, their identity as Britons was challenged in new ways. From this, a unique subgroup of settlers developed, known as planters. In this thesis, I examine the planter community that developed in the small South Central African country of Nyasaland, now Malawi. By examining Nyasaland’s settler community as a case study, I …

Traditional And Modern Breeding Strategies Towards Developing Resilient Crops: Two Case Studies In Tomato, Estefania Tavares Flores

Graduate Theses, Dissertations, and Problem Reports (ETD)

Crop designing for resilience traits to produce satisfactorily under adverse conditions and scenarios is a priority for the future of global food security. In this thesis, two different approaches addressing major stress factors for tomato cropping are presented. We first aimed to domesticate tomato de novo as a high-salinity resistant crop using the wild relative, S. cheesmaniae via gene editing. We conducted single-gene and multiplex knock-out strategies using CRISPR/Cas9 genome editing to create loss-of-function alleles for the domestication-related genes BIF, CycB, J2, EJ2, MULTI, SP, SP5G, and FW11.3 in order to create a novel, halophyte tomato harboring an inherent high-salinity …

Biocompatible And Multifunctional Trityl Spin Probes For Electron Paramagnetic Resonance Spectroscopy, Teresa D. Gluth

Graduate Theses, Dissertations, and Problem Reports (ETD)

The primary objective of my thesis was to develop and utilize a biocompatible multifunctional trityl spin probe for concurrent measurement of pO₂, pH_e, and [P_i] in vivo by electron paramagnetic resonance (EPR) spectroscopy (Chapter 2). My first goal was to synthesize the proposed probe we are terming HOPE71. Secondly, HOPE71 was characterized by X-band and L-band EPR spectroscopy. Next, the biocompatibility of HOPE71 was assessed through an albumin binding test, cytotoxicity assays, and in vivo intravenous tolerance. Then, the use of HOPE71 to measure the target parameters was demonstrated in a breast cancer …

An End-To-End Face Recognition System Evaluation Framework, James Andrew Duncan

Graduate Theses, Dissertations, and Problem Reports (ETD)

The performance of face recognition system components is traditionally reported using metrics such as the Receiver Operating Characteristic (ROC), Cumulative Match Characteristic (CMC), and Identification Error Tradeoff (IET). Recently, new metrics have been published to take advantage of annotation-dense datasets such as IARPA Janus Benchmark-Surveillance and IARPA Janus Benchmark-Multi Domain Face to describe end-to-end face recognition system performance. Unlike traditional (component-level) analysis, end-to-end analysis of a system produces a metric proportional to the experience of a user of a face recognition system. The End-to-End Cumulative Match Characteristic (E2ECMC) summarizes detection, identity consolidation, and identity retrieval performance. The End-to-End Subject Cumulative …

The Relationship Amongst Faith, Perceived Discrimination, Sexuality Acceptance, And Psychological Well-Being In Black Sexual Minority Individuals, Sandra Fanning

Graduate Theses, Dissertations, and Problem Reports (ETD)

The present study explored the relationship amongst faith, internalized homophobia, outness, perceived discrimination, and psychological well-being in Black sexual minorities (BSM). BSM participants (N = 211) completed an online survey assessing these variables. The result of this study indicate that faith is not related to internalized homophobia, outness, perceived discrimination, or psychological well-being in BSM individuals. However, internalized homophobia, outness, and perceived discrimination all independently predict psychological well-being. Explicitly, greater reports of internalized homophobia, outness, and perceived discrimination predicted worse psychological well-being in participants. However, the effects of internalized homophobia and outness were no longer present when accounting for …

Identifying Self-Determined Learning Practices Within Social Media For Teacher Professional Development, Leah Mcjilton

Graduate Theses, Dissertations, and Problem Reports (ETD)

The collective increase of learner-centered teaching and substantial technology use in the classroom has given instructors potential opportunities to support students in developing lifelong learning skills. The ability to manage one’s own learning is an essential skill for lifelong learners in today’s workforce. Heutagogy, or self-determined learning, suggests that individuals have agency with respect to how, what, and when they learn. Heutagogy provides a framework for making the most of these developments, drawing on established learner-centered education theories. The key principles of heutagogy provide a foundation for designing and developing learning environments using social media. In order for teachers to …

Is Care In The Air?: A Crisis Ethics Case Study Of American Airlines’ Communication During The Covid-19 Pandemic, Lily V. Hicks

Graduate Theses, Dissertations, and Problem Reports (ETD)

This research proposes a qualitative case study of American Airlines’ communication during the first month of the COVID-19 global pandemic. Data from the airline’s press releases along with its tweets and a sample of organizational responses to those tweets are offered for proposed analysis using the lenses of Situational Crisis Communication Theory, the Applied Model of Care Considerations, and the body of crisis literature on audience coping and emotions during crises. This in-depth look at a unique communication phenomenon will be a fundamental step in examining how airline communication exhibits ethics or lack thereof and is related to people’s emotions …

A Short Film That Addresses Substance Use Disorders In Rural Communities And Strategies In Prevention And Treatment Of Addiction, Sarah R. Poteracki

Graduate Theses, Dissertations, and Problem Reports (ETD)

This research paper and accompanying video (link to the short film is here: https://drive.google.com/drive/folders/1etDnUmEvkOds8J0EKnq1gnFO79-GggjY) offer insight into the current state of research collaboration surrounding substance use disorders in West Virginia. This professional project explores the importance of collaboration both in a research and clinical setting and in the social realm. The film was shown at the 2nd annual meeting for the Appalachian Node of the National Institute on Drug Abuse Clinical Trials Network on February 25, 2021. I interviewed 14 researchers and experts from a diverse range of disciplines who shared insights and strategies in the prevention and treatment of …

The Impacts Of An Entrepreneurial Course On Secondary Students' Entrepreneurial Self-Efficacy And Entrepreneurial Intentions, Toi E. Hershman

Graduate Theses, Dissertations, and Problem Reports (ETD)

There is considerable agreement that promoting entrepreneurship stimulates economic development and job creation, which helps maintain a country’s economic competitiveness. Entrepreneurship education is a key to increasing the likelihood of potential entrepreneurs. While substantial research has documented strategies for enhancing students' entrepreneurial mindset and building entrepreneurial skills in higher education, entrepreneurship is rarely incorporated into or studied in secondary education. This mixed-method study examined the impact of an online ten-lesson entrepreneurship course on secondary students' entrepreneurial self-efficacy and entrepreneurial intentions. Students took a pre-survey that measured their entrepreneurial self-efficacy and intentions before the course and a post-survey upon completing the …

The Media's Framing Of Incarceration In West Virginia, Patrick John Orsagos

Graduate Theses, Dissertations, and Problem Reports (ETD)

The following is a professional project that examines the way in which the mass incarceration of West Virginians has been framed by the news media. The research presented explains the scope of the problem of mass incarceration, followed by an explanation of research conducted on framing. The literature review explores what other media scholars have published about framing and argues which frame is most dominant in crime reporting by state media. Following this is a methodology for production of a podcast series that utilizes a thematic frame and the practice of solutions journalism to promote dialogue around the systemic issues …

Application Of Project Management Strategies And Tools For An Efficient And Successful Competition-Based Engineering Senior Capstone Design Project, Benton Duane Morris

Graduate Theses, Dissertations, and Problem Reports (ETD)

The industry-level engineering workforce for a project in modern times requires a clear plan and management process to execute the goals of the consumer and the producer. The engineers of tomorrow need the ability to be competitive and successful upon entry into the industry, where there have already been established management tactics for the execution of the company's goals. The mentality within the industry is adaptable to senior collegiate-level competition-based capstone projects. Therefore the West Virginia University EcoCAR Mobility Challenge team has adapted, altered, or adjusted industry-level practices in order to have an overall functioning and effective team that follows …

Design And Synthesis Of Targeted Immunotherapeutic Agents, Md Shohel Rana

Graduate Theses, Dissertations, and Problem Reports (ETD)

The therapeutic monoclonal antibodies are very important tools to fight against the diseases especially in the field of cancer immunotherapy. Many immunotherapeutic antibodies are being used to treat cancer that target multiple different components of the cancer microenvironment. Cells with extracellular juxtacrine ligands [JL-cells] and extracellular juxtacrine receptors [JR-cells] form JL-cell-JR-cell interfaces that produce juxtacrine signals inside JR-cells. [76] Juxtacrine signaling unlike endocrine or paracrine signaling requires no release or cellular uptake of ligands. [76] Immune checkpoint inhibitors are soluble IgG antibodies that block juxtacrine ligand engagements with juxtacrine receptors on tumor or other immune cells. [77] Rapid Nobel Prize …

Unique Biological Applications Of Charge Transfer Dissociation Mass Spectrometry, Halle M. Edwards

Graduate Theses, Dissertations, and Problem Reports (ETD)

The ever-changing landscape of mass spectrometry is driven by gaps in knowledge, and one of the biggest driving forces is the desire to understand the structure and dynamics of biomolecules in living organisms. New and better methods of tandem mass spectrometry are often at the heart of technological developments. Some fragmentation methods are limited to expensive FTICR instruments, some techniques are limited multiply charged precursors, and others are limited to breaking only the weakest bonds in precursor ions; all of which support the pursuit of new activation methods. Charge transfer dissociation (CTD) addresses some of these concerns by providing structurally …