Digital Commons Network^™

Non-Lethal Sampling Methods For Fish Health Assessments Using Smallmouth Bass Micropterus Dolomieu, Lindsey Nicole Hartzell

Graduate Theses, Dissertations, and Problem Reports (ETD)

In the early 2000s, fish kills of different species, including smallmouth bass Micropterus dolomieu, were reported in areas of the Potomac River drainage, including the Shenandoah River in Virginia. Since the first reports of fish kills and lesions affecting smallmouth bass, they have continued to show signs of adverse health effects. Additionally, in some areas of the Potomac River drainage, population declines have occurred, and lethal sampling is discouraged. To develop a holistic, integrative approach to assess fish health, Smallmouth Bass were collected and sampled using non-lethal techniques at three sites within the Shenandoah River drainage, VA and one …

Neural Network-Based Image Compression, Atefeh Khoshkhahtinat

Graduate Theses, Dissertations, and Problem Reports (ETD)

The rapid advancement of information technology and the exponential growth of digital communication have significantly increased the demand for efficient data compression techniques that reduce storage requirements, minimize bandwidth consumption, and accelerate data transmission—without substantially compromising data quality. This dissertation addresses these challenges by investigating and developing advanced learned image compression (LIC) methods, with a particular focus on lossy compression for both natural images and scientific imagery obtained from NASA’s Solar Dynamics Observatory (SDO) mission. Traditional image compression standards—such as JPEG, JPEG2000, BPG, and HEVC—rely on manually engineered transforms and heuristic rules, which often lack the adaptability required to accommodate …

Toward A University-Led Community Indicator Project For West Virginia, Daniel Carson Eades

Graduate Theses, Dissertations, and Problem Reports (ETD)

Rural communities across the United States are experiencing profound social and economic transitions that demand innovative, asset-based approaches to community development (CD). This study responds to calls from West Virginia (WV) community development practitioners, funders, and university leaders for a standardized, contextually relevant framework to assess and track community well-being. The objective of this study was to develop a university-led community indicator project in West Virginia (WV CIP) that incorporates best practices recognized by the literature as critical to successful community-based indicator projects, specifically, the identification of scientifically and normatively grounded indicators rooted in a conceptual framework (the Community Capital …

Identifying The Role And Influence Of Interleukin-27 On The Neonatal Immune Response, Jordan Kane Vance

Graduate Theses, Dissertations, and Problem Reports (ETD)

The first month of life is a critical and vulnerable developmental stage, characterized by a heightened risk of life-threatening infections. Each year, 1.3 million newborns succumb to neonatal bacterial sepsis. The immune system during the neonatal period has unique features that lead to inefficiencies at clearing infection. Early life immunity is characterized by a Th2-biased profile with decreased IL‑12, IFN-γ, and TNF-α, along with increased IL‑6 and IL‑23. Additionally, IL‑27, an immunosuppressive cytokine, is also elevated during this period and further contributes to susceptibility to infection. Early diagnosis and intervention are critical in administering effective care in newborns and there …

Access And Entitlement: Investigating The Contours Of Public Health In Late Colonial Bengal And Post Colonial West Bengal (1920-1960), Ametasree Bhattacharya

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation employs the comparative framework of “Access and Entitlement,” which serves as a metric to measure the goods and services the state could responsively provide to the public. It utilizes this framework to analyze the realm of public health in Bengal/West Bengal before and after decolonization. The main body is divided into two parts: the first three chapters focus on malaria, and the last three on nutrition. The first chapter explores debates over malaria control between 1919 and 1935. The second examines anti-malarial efforts from 1935 to 1947, emphasizing the influence of communal politics and the Second World War …

Development Of A Model To Estimate Engine Crankcase Methane Vent Emission Rates, Juan Pablo Rincon

Graduate Theses, Dissertations, and Problem Reports (ETD)

The primary focus of this research is the modeling and validation of crankcase methane emissions stemming from natural gas combustion engines commonly deployed in the natural gas compression industry. The models employed rely on equations predicting the flow rate and composition of losses, typically generated within reciprocating piston-cylinder systems. Since crankcase emissions originate in a piston–cylinder arrangement, multiple variables were considered in this study, including displaced volume, pressure, temperature, flow, and viscosity (with corrections applied to account for the thermal and compositional effects on the mixture of fluids). The initial data for this research was collected during three measurement campaigns …

"She's Such A Nice Girl": Exploring The Literacy And Identity Formation Practices Of Black Girls In White, Appalachian Communities, Tamicah Tierra Owens

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study examines the experiences and stories of two Black girls in predominantly White Appalachian communities, focusing on the language and literacy practices they employ to navigate and make sense of their Black feminine identities. It focuses on how literacy and language skills acquired from spending quality time with their mothers, engaging in various spaces with friends, and engaging in interest-driven traditional media and/or social media helped them to analyze their communities’ and the larger landscapes’ discourses around race and gender to create and modify their desired identities. This qualitative study employs narrative case study to center the lived experiences …

Watershed-Level Survey Of Antimicrobial Resistance From Onsite Wastewater Systems, Trey Franklin Clark

Graduate Theses, Dissertations, and Problem Reports (ETD)

The emergence of antimicrobial resistance (AMR) has quickly become one of the largest global health and development threats. Research related to environmental modes of transmission of AMR has accelerated in recent years, and the US Environmental Protection Agency is particularly interested in this emerging contaminant. Knowledge of how onsite (decentralized) wastewater treatment systems contribute to this issue is lacking, so this research serves to analyze and quantify the environmental dissemination of AMR and fecal contamination from these sources at a watershed level while using statistical analysis to assess relationships between physiochemical, spatial, and sampling parameters. This research surveyed four watersheds …

A Learning History Of A State Physical Activity Plan, Jessica Nicole Riffee

Graduate Theses, Dissertations, and Problem Reports (ETD)

Physical inactivity remains a persistent public health concern in the United States, disproportionately affecting rural populations like West Virginia. To address statewide physical activity challenges, West Virginia developed one of the nation’s first state level physical activity plans, ActiveWV: 2015, that was revised to ActiveWV: 2030. Limited research has investigated how statewide physical activity plans unfold over time or how stakeholder learning can drive improvement.

This dissertation employed a learning history action research methodology to construct a collective narrative of the development, dissemination, implementation, and evaluation activities across both iterations of the West Virginia Physical Activity Plan. Reflective interviews with …

Development Of Novel Carbohydrate-Based Nanoparticles For Precision Drug Delivery, Krystal Ann Hughes

Graduate Theses, Dissertations, and Problem Reports (ETD)

Nanoparticle-based drug delivery has made tremendous advancements in the last decade. However, several critical factors, including precision drug delivery at the site of interest, long-term storage stability, and controlling release profiles of drugs in the systemic circulation, need to be addressed for successful clinical translation of nanomedicine. This dissertation presents novel carbohydrate-based nanoparticles that achieve precise intracellular delivery and therapeutic release at the disease site. We present the formulation and optimization of polymeric and polymer-lipid hybrid nanoparticles that enable precision intracellular delivery and passive accumulation of therapeutics in the bone marrow. Intracellular delivery is highly impactful and sought after. One …

Developing The 21st Century Piano Studio, Brianna Mae Eddy

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study explores the needs of the contemporary piano studio, including business policies, the use of technologies, mental health and neurodivergence in students, and the influence and use of social media. Focused on the needs of both the private-studio piano teacher and traveling piano teacher, the paper offers insight into studio ownership and management with an emphasis on providing experiences that meet the needs of contemporary students. The paper includes a brief history of private piano instruction as well as information for developing studio policies, business issues related to current tax requirements and forms, and resources for financial and general …

A Qualitative Analysis Of Secondary Mathematics Teachers’ Development Toward Teaching Mathematics For Social Justice, Catherine Lynne Manley

Graduate Theses, Dissertations, and Problem Reports (ETD)

While some might say that mathematics is neutral, free from political and social bias, social justice concerns can be found in the day-to-day actions of teachers in mathematics classrooms. Teaching mathematics for social justice requires teachers to gain knowledge of the world and systems of oppression as well as current efforts to both address systemic issues as well as the fight for those in power to maintain their cultural capital. Mathematics teachers also need to learn the pedagogical practices that support social justice in education and the specific ways in which mathematics content can be used as a tool to …

History Of Federal International Education Policy (1900-2024): A Four-Dimensional View In Action, Winda Wastu Melati

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation examines the history of the evolution of United States international education policy from 1900 to 2024, employing document analysis methodology to explore key themes that have shaped its trajectory. The study utilizes Cooper et al.'s (2004) Four-Dimensional View of Policy theory (normative, structural, constituentive, and technical) to analyze the complex interplay between diplomatic objectives, economic considerations, national security concerns, immigration, internationalization of higher education, and international students in the United States. The research traces major policy shifts from early initiatives like the Boxer Indemnity Scholarship Program to post-9/11 security measures and recent administrative changes by examining primary sources …

The Experiences Of Women College Presidents While Leading Through An Institutional Crisis: The Perceived Successes And Failures Of Crisis Communication Strategies, Madison Marie Speck

Graduate Theses, Dissertations, and Problem Reports (ETD)

This multi-site case study explored the uncommonly discussed yet organic intersection between the study of crisis communication and the study of crisis leadership and in turn, what it means in the context of a college presidency. This study has a unique focus on women presidents at small, private colleges and the ways in which they communicate with various stakeholders during a crisis environment. The research is guided by Boin’s Model of Crisis Leadership which guides and assesses crisis leadership performance; however this study introduces nuances to the framework that are suggested as a result of the findings; most of which …

Depicting The Donald: How Framing Of Donald Trump In Media Changed Throughout The Course Of His 2015-2016 United States Presidential Campaign, Jakob O. Janoski

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study examined how framing of Donald Trump in online news images may have changed throughout the course of his 2015-2016 United States presidential campaign. Previous research suggests that Republican presidential candidates may get more coverage but not necessarily be framed as more favorable (Moriarty and Popovich, 1988). The content analysis comprised of 18 constructed weeks in which images from various outlets were analyzed in nine categories (e.g., “facial expression” and “posture”) and coded as either “more favorable,” “N/A” or “less favorable.” It was found that image favorability of Trump dipped from the Pre-Primary period to the Primary period then …

A Critical Event Narrative Analysis Of African Women Immigrant Entrepreneurs In The United States: Impacts Before, During, And After The Covid-19 Pandemic, Damilola T. Fasinu

Graduate Theses, Dissertations, and Problem Reports (ETD)

This doctoral research presents a qualitative critical event narrative study focused on African Women Immigrant Entrepreneurs (AWIE) in the United States during the COVID-19 pandemic. The study aims to explore the unique challenges, coping mechanisms, and resilience strategies of AWIE by examining their experiences before, during, and after the pandemic. The research is driven by three guiding questions: (1) How do AWIE describe their experience before the pandemic? (2) During the pandemic? (3) After the pandemic? This inquiry provides a comprehensive narrative, capturing the challenges and successes experienced in the pre-pandemic environment, documenting the immediate impacts of the pandemic on …

Evaluation Of Probable Maximum Precipitation (Pmp) For West Virginia To Predict Current And Future Pmp & Utilizing Acid Mine Drainage (Amd) Sludge In Reclamation, Grace Katherine Kerr

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis includes two main topics: 1) evaluation of probable maximum precipitation (PMP) for West Virginia to predict current and future PMP, and 2) utilizing acid mine drainage (AMD) sludge as a reclamation plan.

Probable maximum precipitation (PMP) is essential for dam design as well as for the inspection, operation, maintenance, and repairs of these facilities. West Virginia Department of Environmental Protection Dam Safety utilizes the 6-hr, 10-mi² (26-km²) PMP established by Hydrometeorological Report (HMR) 51 based on the analysis of extreme rainfall. These PMP are outdated because there have been unaccounted for extreme rainfall events that …

Application Of Interpretable Machine Learning Methods To Study The Disease Characteristics And Healthcare Expenditures In Hodgkin’S Lymphoma, Zasim Azhar Dil Hasan Siddiqui

Graduate Theses, Dissertations, and Problem Reports (ETD)

Hodgkin’s lymphoma (HL) is a rare malignancy of lymphocytes that predominantly occurs in young adults aged 20-30 years or elderly individuals aged 65-75 years. Despite its low incidence, there were an estimated 223,512 HL survivors in the US in 2020. Hodgkin’s lymphoma shows a favorable prognosis among young adults, with a high cure rate of 85-90%; however, older adults experience poor prognosis, with a 5-year overall survival rate of 40-55% in patients over 60 years. HL survivors incur high total and out-of-pocket (OOP) healthcare expenditures, averaging $78,183 and $4,180 per patient in the first year after diagnosis, highlighting a considerable …

At The Table, Payton Olivia Brown

Graduate Theses, Dissertations, and Problem Reports (ETD)

This written document is the accompanying thesis for my Master of Fine Arts exhibition, At the Table. This document, as well as my artwork, investigates the profound impact that food has on one’s life by strengthening connections with others, upholding traditions, and cherishing memories. It also elaborates on the inspirations, research, and experimentation utilized in the process of creating the exhibition. Through an array of paintings, mixed media, and sculptural work, this exhibition is intended to depict my own personal experiences and memories in relation to food.

Although I am making autobiographical artwork, I am also trying to portray the …

Community Resource Programs Impact On Marginalized Communities Access To Health Care Services: A Program Development Project, Alexis N. Foehrkolb

Graduate Theses, Dissertations, and Problem Reports (ETD)

Caring for children and meeting their needs comes with a variety of considerations regarding temperament, developmental progress, and socioeconomic impact. For children with special healthcare needs (CSHCN), those considerations become more complex. Community resource programs are designed to help families of CSHCN get access to the resources they need regarding general and healthcare services. A program was developed in collaboration with Parents Place of Maryland (PPMD) to create materials effective in educating parents of CSHCN on desired topics of interest, create a virtual environment where parents felt safe asking questions regarding specific topics of interest, and determine the most effective …

Anxiety And Depression In Older Adults Post Deepwater Horizon Oil Spill, Mickaela R. Reed

Graduate Theses, Dissertations, and Problem Reports (ETD)

Research has investigated challenges that are created when one experiences a disaster within populations such as older adults and other vulnerable groups of people. However, there is little to no consideration given to how age in combination with trauma history are related to well-being after a disaster. Using two theories, socioemotional selectivity theory (SST, Carstensen, 2006) and the strength and vulnerability integration model (SAVI, Charles, 2010). I compared older adults post disaster vulnerabilty to depression and anxiety to that of younger adults with trauma history as a moderator. The 2,508 participants in the current study were from the Survey of …

Effect Of Haemonchus Contortus Excretory/Secretory Protein On Differences In Host Neutrophil Migration, Hannah Grace Teddleton

Graduate Theses, Dissertations, and Problem Reports (ETD)

An excretory/secretory (E/S) product, common to many helminths, is neutrophil inhibitory factor (NIF) which negatively affects neutrophil migration and activity. Due to differences in neutrophil accumulation between parasite resistant St. Croix STC and parasite susceptible Suffolk (SUF) sheep, we hypothesized that Hc-NIF may inhibit migration of SUF and not STC neutrophils. Previous studies have demonstrated that Hc produces NIF but is not commercially available. To test our hypothesis, neutrophils were cultured from STC and SUF sheep in the presence of Ancylostoma caninum-derived NIF (Ac-NIF) and measure chemotaxis to Interleukin-8 (IL-8), HcLA or H. contortus third-stage excretory/secretory (E/S) products. Neutrophils were …

Resource Affluence And Sustainable Consumer Behavior, Liguo Liu

Graduate Theses, Dissertations, and Problem Reports (ETD)

While resource affluence is desired by most individuals, it may not always be advantageous for a collective group. Recent research documents some “dark side” effects associated with resource affluence, such as reducing people’s willingness to help others or leading to unethical behaviors (e.g., Piff et al. 2012; Vohs et al. 2016). Building on this body of work and advances in sustainability research, this study investigates the impact of financial affluence on sustainable consumer behavior. Using a multi-method approach (archival data and experiments), this study demonstrates that financial affluence leads to less sustainable consumer behaviors compared to a control group, across …

A Randomized Need-Supportive Intervention With U.S. Youth Hockey Coaches, Diane Benish

Graduate Theses, Dissertations, and Problem Reports (ETD)

Coach behaviors impact several essential athlete factors such as the quality of athlete motivation and psychological functioning and yet, many youth coaches remain untrained in motivation and athlete-centered principles. This study’s aim was to explore the efficacy of a need-supportive intervention on youth hockey coaches’ attitudes toward, and reported use of, need-supportive and/or need-thwarting approaches. Participants included 25 youth hockey coaches randomly assigned to an intervention or delayed control condition. Grounded in Self-Determination Theory, the intervention included four sessions within which coaches learned how to adopt need-supportive coaching strategies and reduce need-thwarting tactics. A mixed-methods approach guided the evaluation of …

Impact Of Tiered Implementation Of Clinical Decision Support System For Acute Kidney Injury And Nephrotoxin Exposure In Cardiac Surgery Patients, Christopher M. Justice Ii

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Nephrotoxin exposure may worsen kidney injury and impair kidney recovery if continued in patients with acute kidney injury (AKI).

Objective: To determine if tiered implementation of a clinical decision support system (CDSS) would reduce nephrotoxin use in cardiac surgery patients with AKI.

Methods: We assessed patients admitted to the cardiac surgery intensive care unit at a tertiary care center from January 2020 to December 2021, and August 2022 to September 2023. A passive electronic AKI alert was activated in Jul 2020, followed by an electronic nephrotoxin alert in March 2023. In this alert, active nephrotoxic medication orders resulted in …

Increasing First-Attempt Endotracheal Intubation Success Rates In The Aeromedical Environment, Jared Copeland

Graduate Theses, Dissertations, and Problem Reports (ETD)

Problem Statement: In 2022, the first-attempt endotracheal intubation success rate of an aeromedical agency had steadily declined and was currently below the international average of 88.48%. This decreased success rate potentially placed patients at risk for adverse events that increase morbidity and mortality. Background: Patients who experience a failed first-attempt intubation are at greater risk of intubation related complications. These complications include hypoxemia episodes, severe arrhythmias, pulmonary aspiration, hypotension episodes, cardiac arrest, and death. Literature Review: Preoxygenation, patient positioning, maintenance of oxygenation, drug selection, and device utilization have been found to increase first-attempt endotracheal success rates. Project Aims: The project …

Risk Of Parasiticides To Dung-Associated Beetles In West Virginia, Haylie J. Brown

Graduate Theses, Dissertations, and Problem Reports (ETD)

Ecosystem services provided by dung-associated beetles, such as reducing pasture fouling, parasite suppression, supporting nutrient recycling, and increasing water infiltration, contribute to animal and pasture health. However, parasiticides used to manage cattle parasites, particularly flies and helminths, in West Virginia, can adversely affect these non-target beetles. We assessed the exposure and impact of some parasiticides used in WV including Clarifly^® (active ingredient [a.i.] diflubenzuron), Cydectin^® (a.i. moxidectin), LongRange^® (a.i. eprinomectin), and Safe-guard^® (a.i. fenbendazole). In Chapter 1, we review the use of parasiticides in the US and their non-target effects on beneficial dung-associated beetles. In Chapter …

Role Of Β4b-Tubulin (Tubb4b) In The Sensory System And Spermatogenesis, Urikhan Sanzhaeva

Graduate Theses, Dissertations, and Problem Reports (ETD)

Microtubules are ubiquitous cytoskeletal filaments essential in the function of eukaryotic cells. These polymers, comprised of αβ-tubulin heterodimers, are critical for cell division, intracellular transport, and formation of the axonemes of cilia and flagella. This functional diversity of microtubules is attributed to the incorporation of various α- and β-tubulin isotypes encoded by different genes. Indeed, mutations in human tubulin genes have been linked to various tissue-specific diseases, suggesting a unique function for each tubulin isotype. Mutations in the β4B-tubulin gene (TUBB4B) are associated with sensorineural hearing loss, Leber Congenital Amaurosis (LCA), a severe childhood blindness, and primary ciliary dyskinesia …

The Effects Of Diet-Induced Obesity On Cerebral Microvascular Bioenergetics, Alec Anthony Hanshew

Graduate Theses, Dissertations, and Problem Reports (ETD)

Obesity is a worldwide epidemic but is especially a concern in the United States with over 40% of the population being obese. Obesity is known to cause increased metabolic demand, systemic inflammation, peripheral vascular dysfunction, and increased levels of oxidative stress and reactive oxygen species (ROS). However, the role of obesity on cerebrovascular bioenergetic function has not been fully elucidated. This study aimed to determine the impact of diet-induced obesity on cerebrovascular bioenergetics. 72, 6-month-old C57Bl/6 male and female mice were randomized into control and HFD groups. Control mice were subjected to the feeding of standard chow (18% fat, 24% …

Becoming A Homemaker In Appalachia: Building Bridges In Women's Flat Track Roller Derby, Jessica Lynn Lough

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study sought to explore how six women in Central Appalachia negotiated embodied subjectivity and agency across discourses and gendered power relations. Women living in central Appalachia who play roller derby occupy a unique social position in which to position this study, as many are simultaneously challenging traditional gender norms and engaging in a highly physical and competitive sport that involves using their bodies relationally. Specifically, by conceiving women as vehicles of power and women’s flat track roller derby as a public pedagogy, I sought to trace what ‘doing’ a roller derby identity does to transform and advance their knowledge …