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Mutation In Prkra Results In Cerebellar Abnormality And Reduced Elf2Α Phosphorylation In A Model Of Dyt-Prkra, Samuel B. Burnett, Allison M. Culver, Tricia A. Simon, Taylor Rowson, Kenneth Frederick, Kristina Palmer, Stephen A. Murray, Shannon W. Davis Oct 2024

Mutation In Prkra Results In Cerebellar Abnormality And Reduced Elf2Α Phosphorylation In A Model Of Dyt-Prkra, Samuel B. Burnett, Allison M. Culver, Tricia A. Simon, Taylor Rowson, Kenneth Frederick, Kristina Palmer, Stephen A. Murray, Shannon W. Davis

Faculty Publications

Variants in the PRKRA gene, which encodes PACT, cause the early-onset primary dystonia DYT-PRKRA, a movement disorder associated with disruption of coordinated muscle movements. PACT and its murine homolog RAX activate protein kinase R (PKR; also known as EIF2AK2) by a direct interaction in response to cellular stressors to mediate phosphorylation of the α subunit of eukaryotic translation initiation factor 2 (eIF2α). Mice homozygous for a naturally arisen, recessively inherited frameshift mutation, Prkralear-5J, exhibit progressive dystonia. In the present study, we investigated the biochemical and developmental consequences of the Prkralear-5J mutation. Our results indicated that the …


Coastal Wetlands In The Anthropocene, John Day, Edward Anthony, Robert Costanza, Douglas Edmonds, Joel Gunn, Charles Hopkinson, Michael E. Mann, James Morris, Michael Osland, Tracy Quirk, Andre Rovai, John Rybczyk, Thomas Spencer, Jessica Stephens, Jaia Syvitski, Robert Twilley, Jenneke Visser, John R. White Oct 2024

Coastal Wetlands In The Anthropocene, John Day, Edward Anthony, Robert Costanza, Douglas Edmonds, Joel Gunn, Charles Hopkinson, Michael E. Mann, James Morris, Michael Osland, Tracy Quirk, Andre Rovai, John Rybczyk, Thomas Spencer, Jessica Stephens, Jaia Syvitski, Robert Twilley, Jenneke Visser, John R. White

Faculty Publications

We review the functioning and sustainability of coastal marshes and mangroves. Urbanized humans have a 7,000-year-old enduring relationship to coastal wetlands. Wetlands include marshes, salt flats, and saline and freshwater forests. Coastal wetlands occur in all climate zones but are most abundant in deltas. Mangroves are tropical, whereas marshes occur from tropical to boreal areas. Quantification of coastal wetland areas has advanced in recent years but is still insufficiently accurate. Climate change and sea-level rise are predicted to lead to significant wetland losses and other impacts on coastal wetlands and the humans associated with them. Landward migration and coastal retreat …


Hydrodynamic Exposure – On The Quest To Deriving Quantitative Metrics For Mariculture Sites, Oliver Lojek, Nils Goseberg, Heidi Moe Føre, Tobias Dewhurst, Thea Bölker, Kevin Gerald Heasman, Bela H. Buck, David W. Fredriksson, Samuel Rickerich Oct 2024

Hydrodynamic Exposure – On The Quest To Deriving Quantitative Metrics For Mariculture Sites, Oliver Lojek, Nils Goseberg, Heidi Moe Føre, Tobias Dewhurst, Thea Bölker, Kevin Gerald Heasman, Bela H. Buck, David W. Fredriksson, Samuel Rickerich

Faculty Publications

This work attempts to define metrics for hydrodynamic exposure, using known oceanographic variables to provide a universal site assessment method for mariculture structures. Understanding environmental conditions driving open-ocean mariculture siting is crucial in establishing consistent ocean governance, minimizing adverse environmental impacts, and facilitating economically sustainable farm operations. To provide a metric of oceanic conditions and associated requirements for structural design and operation of aquaculture systems, six Exposure Indices (EI) are proposed that consider physical energy levels related to hydrodynamic forces at a site. Four of the proposed indices consider only environmental conditions, while the other two also consider the dimensions …


Data-Driven Sparse Sensor Placement Optimization On Wings For Flight-By-Feel: Bioinspired Approach And Application, Alex C. Hollenbeck, Atticus J. Beachy, Ramana V. Grandhi, Alexander M. Pankonien Oct 2024

Data-Driven Sparse Sensor Placement Optimization On Wings For Flight-By-Feel: Bioinspired Approach And Application, Alex C. Hollenbeck, Atticus J. Beachy, Ramana V. Grandhi, Alexander M. Pankonien

Faculty Publications

Flight-by-feel (FBF) is an approach to flight control that uses dispersed sensors on the wings of aircraft to detect flight state. While biological FBF systems, such as the wings of insects, often contain hundreds of strain and flow sensors, artificial systems are highly constrained by size, weight, and power (SWaP) considerations, especially for small aircraft. An optimization approach is needed to determine how many sensors are required and where they should be placed on the wing. Airflow fields can be highly nonlinear, and many local minima exist for sensor placement, meaning conventional optimization techniques are unreliable for this application. The …


Rootzone Soil Moisture Dynamics Using Terrestrial Water-Energy Coupling, Vinit Sehgal, Binayak P. Mohanty, Rolf H. Reichle Oct 2024

Rootzone Soil Moisture Dynamics Using Terrestrial Water-Energy Coupling, Vinit Sehgal, Binayak P. Mohanty, Rolf H. Reichle

Faculty Publications

A lack of high-density rootzone soil moisture (θRZ) observations limits the estimation of continental-scale, space-time contiguous θRZ dynamics. We derive a proxy of daily θRZ dynamics — active rootzone degree of saturation (SRZ) — by recursive low-pass (LP) filtering of surface soil moisture (θS) within a terrestrial water-energy coupling (WEC) framework. We estimate the LP filter parameters and WEC thresholds for the piecewise-linear coupling between SRZ and evaporative fraction (EF) at remote sensing and field scale over the Contiguous U.S. We use θS from the Soil Moisture Active-Passive (SMAP) satellite and 218 in-situ stations, with EF from the Moderate Resolution …


Finite Sum Of Integral Operators From The Fractional Cauchy Spaces To Bloch-Type And Zygmund-Type Spaces, Rita A. Hibschweiler, Ajay K. Sharma Oct 2024

Finite Sum Of Integral Operators From The Fractional Cauchy Spaces To Bloch-Type And Zygmund-Type Spaces, Rita A. Hibschweiler, Ajay K. Sharma

Faculty Publications

The family of fractional Cauchy transforms, defined on the open unit disc in the complex plane, is of classical and modern interest. Membership of an analytic function in the family is determined by the requirement that the function can be expressed as an integral of a certain kernel against a complex Borel measure on the disc. Such an integral representation imposes a growth condition on the function and its derivatives. This exposes a connection between the families of Cauchy transforms and familiar spaces of analytic functions, such as the Bloch spaces and the Zygmund space. The notion of a composition …


Finite Sum Of Integral Operators From The Fractional Cauchy Spaces To Bloch-Type And Zygmund-Type Spaces, Rita A. Hibschweiler, Ajay K. Sharma Oct 2024

Finite Sum Of Integral Operators From The Fractional Cauchy Spaces To Bloch-Type And Zygmund-Type Spaces, Rita A. Hibschweiler, Ajay K. Sharma

Faculty Publications

The family of fractional Cauchy transforms, defined on the open unit disc in the complex plane, is of classical and modern interest. Membership of an analytic function in the family is determined by the requirement that the function can be expressed as an integral of a certain kernel against a complex Borel measure on the disc. Such an integral representation imposes a growth condition on the function and its derivatives. This exposes a connection between the families of Cauchy transforms and familiar spaces of analytic functions, such as the Bloch spaces and the Zygmund space. The notion of a composition …


The Overlooked First Intercostal Ligament: Does It Help To Stabilize The Weberian Apparatus?, Jake Leyhr, Tatjana Haitina, Nathan C. Bird Oct 2024

The Overlooked First Intercostal Ligament: Does It Help To Stabilize The Weberian Apparatus?, Jake Leyhr, Tatjana Haitina, Nathan C. Bird

Faculty Publications

The Weberian apparatus is a novel hearing adaptation that facilitates increased hearing sensitivity in otophysan fishes. The apparatus is a complex system composed of modifications to anterior vertebral elements, the inner ear, and the swim bladder. A critical piece of the system that often receives minor attention are the various ligaments that bridge these three regions. The most famous of the ligaments is the interossicular ligament, which connects the Weberian ossicle chain (scaphium–intercalarium–tripus). Several other ligaments are present, including the suspensor (tripus to parapophysis 4) and the triple ligament (tripus–os suspensorium–tunica externa). Here, by combining diffusible iodine-based contrast enhancement (DICE) …


Physical Development And Sociocultural Context Influences On Children’S Physical Activity, Alessandro Hervaldo Nicolai Ré, Maria Teresa Cattuzzo, David F. Stodden Ph.D., Guilherme Dos Santos, Albert Lucas Olinto Tertuliano, Carlos Bandeira De Mello Monteiro, Diogo Henrique Constantino Coledam, Anthony David Okely Oct 2024

Physical Development And Sociocultural Context Influences On Children’S Physical Activity, Alessandro Hervaldo Nicolai Ré, Maria Teresa Cattuzzo, David F. Stodden Ph.D., Guilherme Dos Santos, Albert Lucas Olinto Tertuliano, Carlos Bandeira De Mello Monteiro, Diogo Henrique Constantino Coledam, Anthony David Okely

Faculty Publications

Objective:

To examine the predictive strength of cardiorespiratory fitness (CRF), motor competence (MC), maternal educational status, and parental perception of their children’s favorite leisure activities for meeting physical activity (PA) guidelines of each gender among children aged 3–6 years.

Methods: This is a cross-sectional study with 367 preschoolers (53% girls), assessing CRF (PREFIT 20m shuttle run), MC (battery of motor skills), PA (accelerometry), maternal education and parental perception of children’s preferred leisure (questionnaires). Factorial analysis of covariance, multiple logistic regression, and chi-square tests were conducted.

Results: In both genders, CRF was associated with meeting PA guidelines (girls: odds ratio [OR] …


Adding The Third Dimension: 3d Convolutional Neural Network Diagnosis Of Temporal Lobe Epilepsy, Erik Kaestner, Reihaneh Hassanzadeh, Ezequiel Gleichgerrcht, Kyle Hasenstab, Rebecca W. Roth, Allen Chang, Theodor Rüber, Kathryn A. Davis, Patricia Dugan, Ruben Kuzniecky, Julius Fridriksson Ph.D., Alexandra Parashos, Anto I. Bagić, Daniel L. Drane, Simon S. Keller, Vince D. Calhoun, Anees Abrol, Leonardo Bonilha, Carrie R. Mcdonald Oct 2024

Adding The Third Dimension: 3d Convolutional Neural Network Diagnosis Of Temporal Lobe Epilepsy, Erik Kaestner, Reihaneh Hassanzadeh, Ezequiel Gleichgerrcht, Kyle Hasenstab, Rebecca W. Roth, Allen Chang, Theodor Rüber, Kathryn A. Davis, Patricia Dugan, Ruben Kuzniecky, Julius Fridriksson Ph.D., Alexandra Parashos, Anto I. Bagić, Daniel L. Drane, Simon S. Keller, Vince D. Calhoun, Anees Abrol, Leonardo Bonilha, Carrie R. Mcdonald

Faculty Publications

Convolutional neural networks (CNN) show great promise for translating decades of research on structural abnormalities in temporal lobe epilepsy into clinical practice. Three-dimensional CNNs typically outperform two-dimensional CNNs in medical imaging. Here we explore for the first time whether a three-dimensional CNN outperforms a two-dimensional CNN for identifying temporal lobe epilepsy-specific features on MRI. Using 1178 T1-weighted images (589 temporal lobe epilepsy, 589 healthy controls) from 12 surgical centres, we trained 3D and 2D CNNs for temporal lobe epilepsy versus healthy control classification, using feature visualization to identify important regions. The 3D CNN was compared to the 2D model and …


A Comparison Of Gaussian Processes And Polynomial Chaos Emulators In The Context Of Haemodynamic Pulse–Wave Propagation Modelling, L. Mihaela Paun, Mitchel J. Colebank, Dirk Husmeier Oct 2024

A Comparison Of Gaussian Processes And Polynomial Chaos Emulators In The Context Of Haemodynamic Pulse–Wave Propagation Modelling, L. Mihaela Paun, Mitchel J. Colebank, Dirk Husmeier

Faculty Publications

Computational modelling of the cardiovascular system is a promising future direction for patient-specific healthcare. However, the computational cost of these simulators is a bottleneck for their practical use in clinic for real-time digital twins. Emulation can overcome this, yet an extensive investigation into cardiovascular emulators is warranted. In this study, we emulate two one-dimensional haemodynamics models of the pulmonary circulation and compare two common emulation strategies: Gaussian processes (GPs) and polynomial chaos expansions (PCEs). We start by reducing the parameter space of the models through global sensitivity analysis, and then compare both emulation strategies using a multivariate, time-series output …


The Genomes Of All Lungfish Inform On Genome Expansion And Tetrapod Evolution, Manfred Schartl, Joost M. Woltering, Iker Irisarri, Kang Du, Susanne Kneitz, Martin Pippel, Thomas Brown, Paolo Franchini, Jing Li, Ming Li, Mateus Adolfi, Sylke Winkler, Josane De Freitas Sousa, Zhuoxin Chen, Sandra Jacinto, Evgeny Z. Kvon, Luis Rogério Correa De Oliveira, Erika Monteiro, Danielson Baia Amaral, Thorsten Burmester, Domitille Chalopin, Alexander Suh, Eugene Myers, Oleg Simakov, Igor Schneider, Axel Meyer Oct 2024

The Genomes Of All Lungfish Inform On Genome Expansion And Tetrapod Evolution, Manfred Schartl, Joost M. Woltering, Iker Irisarri, Kang Du, Susanne Kneitz, Martin Pippel, Thomas Brown, Paolo Franchini, Jing Li, Ming Li, Mateus Adolfi, Sylke Winkler, Josane De Freitas Sousa, Zhuoxin Chen, Sandra Jacinto, Evgeny Z. Kvon, Luis Rogério Correa De Oliveira, Erika Monteiro, Danielson Baia Amaral, Thorsten Burmester, Domitille Chalopin, Alexander Suh, Eugene Myers, Oleg Simakov, Igor Schneider, Axel Meyer

Faculty Publications

The genomes of living lungfishes can inform on the molecular-developmental basis of the Devonian sarcopterygian fish–tetrapod transition. We de novo sequenced the genomes of the African (Protopterus annectens) and South American lungfishes (Lepidosiren paradoxa). The Lepidosiren genome (about 91 Gb, roughly 30 times the human genome) is the largest animal genome sequenced so far and more than twice the size of the Australian (Neoceratodus forsteri)1 and African2 lungfishes owing to enlarged intergenic regions and introns with high repeat content (about 90%). All lungfish genomes continue to expand as some transposable elements (TEs) are still active today. In particular, …


Examination Of Photoinduced Radicals In Two Crystal Forms Of Triphenylamine Bis-Urea Macrocycles, Md Faizul Islam, Gamage Isuri P. Wijesekera, Anmon J. Sindt, Mark D. Smith, Linda S. Shimizu Oct 2024

Examination Of Photoinduced Radicals In Two Crystal Forms Of Triphenylamine Bis-Urea Macrocycles, Md Faizul Islam, Gamage Isuri P. Wijesekera, Anmon J. Sindt, Mark D. Smith, Linda S. Shimizu

Faculty Publications

This study probes two solvates of triphenylamine (TPA) bis-urea macrocycle 1 and their activated structures to evaluate their maximum photoinduced radicals (PIRs), the subsequent decay of the radicals, and their regeneration. The hierarchical assembly of TPAs shows promise in stabilizing less substituted derivatives, potentially expanding the utility of TPAs that lack stabilizing para-substituents. Single crystal structure analysis reveals that host 1 adopts a planar conformation with the two ureas pointing in opposite directions when dimethoxyethane (DME) is encapsulated within the channel. Whereas previously, 1 adopted a bowl-shaped conformation with the two ureas pointing in the same direction (syn …


Examination Of Photoinduced Radicals In Two Crystal Forms Of Triphenylamine Bis-Urea Macrocycles, Md Faizul Islam, Gamage Isuri P. Wijesekera, Ammon J. Sindt, Mark D. Smith, Linda S. Shimizu Oct 2024

Examination Of Photoinduced Radicals In Two Crystal Forms Of Triphenylamine Bis-Urea Macrocycles, Md Faizul Islam, Gamage Isuri P. Wijesekera, Ammon J. Sindt, Mark D. Smith, Linda S. Shimizu

Faculty Publications

This study probes two solvates of triphenylamine (TPA) bis-urea macrocycle 1 and their activated structures to evaluate their maximum photoinduced radicals (PIRs), the subsequent decay of the radicals, and their regeneration. The hierarchical assembly of TPAs shows promise in stabilizing less substituted derivatives, potentially expanding the utility of TPAs that lack stabilizing para-substituents. Single crystal structure analysis reveals that host 1 adopts a planar conformation with the two ureas pointing in opposite directions when dimethoxyethane (DME) is encapsulated within the channel. Whereas previously, 1 adopted a bowl-shaped conformation with the two ureas pointing in the same direction (syn …


The Provenance Of A Pali- And Thai-Language Manuscript At The Rollins College Library: A Buddhist Book Of Merit And Its Long Journey From Southeast Asia To America, Wenxian Zhang Oct 2024

The Provenance Of A Pali- And Thai-Language Manuscript At The Rollins College Library: A Buddhist Book Of Merit And Its Long Journey From Southeast Asia To America, Wenxian Zhang

Faculty Publications

Through researching the provenance of a Buddhist manuscript written in the Pali and Thai languages currently held at Rollins, this article seeks to answer the question of how a religious document created in Thailand ended up in a liberal arts college library in America. Regarded as an act of devotion by many Buddhist followers in Southeast Asia, the use of folding manuscripts (samut khoi) has been observed for centuries. The folding manuscripts served as handbooks and chanting manuals for Buddhist monks, who often recited in religious ceremonies while paying tributes to the deceased, with the hope of reincarnation in a …


The Role Of Benthic Fluxes In Acidifying The Bottom Waters In The Northern Gulf Of Mexico Hypoxic Zone Based On An Updated Water Column Biogeochemical-Seabed Diagenetic And Sediment Transport Model, Dongxiao Yin, Linlin Cui, Courtney K. Harris, Julia M. Moriarty, Hannah Beck, Kanchan Maiti Oct 2024

The Role Of Benthic Fluxes In Acidifying The Bottom Waters In The Northern Gulf Of Mexico Hypoxic Zone Based On An Updated Water Column Biogeochemical-Seabed Diagenetic And Sediment Transport Model, Dongxiao Yin, Linlin Cui, Courtney K. Harris, Julia M. Moriarty, Hannah Beck, Kanchan Maiti

Faculty Publications

The seabed and the water column are tightly coupled in shallow coastal environments. Numerical models of seabed-water interaction provide an alternative to observational studies that require concurrent measurements in both compartments, which are hard to obtain and rarely available. Here, we present a coupled model that includes water column biogeochemistry, seabed diagenesis, sediment transport and hydrodynamics. Our model includes realistic representations of biogeochemical reactions in both seabed and water column, and fluxes at their interface. The model was built on algorithms for seabed-water exchange in the Regional Ocean Modeling System and expanded to include carbonate chemistry in seabed. The updated …


Financial Impacts Of 2020 Labor Day Wildfires To Oregon Highways, Kevin Christiansen, Rubayet Bin Mostafiz, Ayat Al Assi, Robert V. Rohli, Carol J. Friedland Oct 2024

Financial Impacts Of 2020 Labor Day Wildfires To Oregon Highways, Kevin Christiansen, Rubayet Bin Mostafiz, Ayat Al Assi, Robert V. Rohli, Carol J. Friedland

Faculty Publications

Wildfire-caused damage to highways has a significant financial cost to the local, regional, and state jurisdictions where they occur. This study examines the financial ramifications of the harm caused to highways by megafires, using a case study of the highways impacted in the U.S. state of Oregon by the five megafires that occurred during the 2020 Labor Day wildfires. This study proposes a method to classify financial road damage from these wildfires based upon curated datasets collected from the Oregon Department of Transportation (ODOT). Hence, this study presents a dataset with labeled classes, which include physical, roadway, and traffic. Physical …


Workplace Bullying In Louisiana Academic Libraries: Exploring Worker Status And Demographics, Justin Savage, Andrea Hebert, Catherine Baird Oct 2024

Workplace Bullying In Louisiana Academic Libraries: Exploring Worker Status And Demographics, Justin Savage, Andrea Hebert, Catherine Baird

Faculty Publications

Bullying is a phenomenon that exists across cultures, societies, and even species. It can be found everywhere, including the workplace. The present study investigates workplace bullying amongst an approximated census sample of Louisiana academic library workers. Using the Negative Acts Questionnaire—Revised (NAQ-R), the study explores the relationships between experiencing workplace bullying and librarian status, tenure status, years in the profession, age, gender, and race. Although no statistically significant relationships were found between variables, the findings add to a growing body of literature that explores the interrelations of demographic and environmental contexts and bullying experiences.


Extensions Of Open Science For Applied Behavior Analysis: Preregistration For Single-Case Experimental Designs, Matt Tincani, Shawn P. Gilroy, Art Dowdy Oct 2024

Extensions Of Open Science For Applied Behavior Analysis: Preregistration For Single-Case Experimental Designs, Matt Tincani, Shawn P. Gilroy, Art Dowdy

Faculty Publications

Open science practices are designed to enhance the utility, integrity, and credibility of scientific research. This article highlights how preregistration in open science practice can be leveraged to enhance the rigor and transparency of single-case experimental designs within an applied behavior analysis framework. We provide an overview of the benefits of preregistration including increased transparency, reduced risk of researcher bias, and improved replicability, and we review the specific contexts under which these practices most benefit the proposed framework. We discuss potential concerns with and unique considerations for preregistering experiments that use single-case designs, with practical guidance for researchers who are …


Long-Term Effects Of Climate Change On Juvenile Bull Shark Migratory Patterns, Philip Matich, Jeffrey D. Plumlee, Walter Bubley, Tobey H. Curtis, J. Marcus Drymon, Lindsay L. Mullins, Oliver N. Shipley, Thomas C. Tinhan, Mark R. Fisher Oct 2024

Long-Term Effects Of Climate Change On Juvenile Bull Shark Migratory Patterns, Philip Matich, Jeffrey D. Plumlee, Walter Bubley, Tobey H. Curtis, J. Marcus Drymon, Lindsay L. Mullins, Oliver N. Shipley, Thomas C. Tinhan, Mark R. Fisher

Faculty Publications

Seasonal variability in environmental conditions is a strong determinant of animal migrations, but warming temperatures associated with climate change are anticipated to alter this phenomenon with unknown consequences. We used a 40-year fishery-independent survey to assess how a changing climate has altered the migration timing, duration and first-year survival of juvenile bull sharks (Carcharhinus leucas). From 1982 to 2021, estuaries in the western Gulf of Mexico (Texas) experienced a mean increase of 1.55°C in autumn water temperatures, and delays in autumn cold fronts by ca. 0.5 days per year. Bull shark migrations in more northern estuaries concomitantly changed, with departures …


A Quantitative Adverse Outcome Pathway For Embryonic Activation Of The Aryl Hydrocarbon Receptor Of Fishes By Polycyclic Aromatic Hydrocarbons Leading To Decreased Fecundity At Adulthood, Jon A. Doering, Justin Dubiel, Eric Stock, Cameron H. Collins, Ian Frick, Hunter M. Johnson, Christopher M. Lowrey-Dufour, Justin G.P. Miller, Zhe Xia, Gregg T. Tomy, Steve Wiseman Oct 2024

A Quantitative Adverse Outcome Pathway For Embryonic Activation Of The Aryl Hydrocarbon Receptor Of Fishes By Polycyclic Aromatic Hydrocarbons Leading To Decreased Fecundity At Adulthood, Jon A. Doering, Justin Dubiel, Eric Stock, Cameron H. Collins, Ian Frick, Hunter M. Johnson, Christopher M. Lowrey-Dufour, Justin G.P. Miller, Zhe Xia, Gregg T. Tomy, Steve Wiseman

Faculty Publications

Quantitative adverse outcome pathways (qAOPs) describe the response–response relationships that link the magnitude and/or duration of chemical interaction with a specific molecular target to the probability and/or severity of the resulting apical-level toxicity of regulatory relevance. The present study developed the first qAOP for latent toxicities showing that early life exposure adversely affects health at adulthood. Specifically, a qAOP for embryonic activation of the aryl hydrocarbon receptor 2 (AHR2) of fishes by polycyclic aromatic hydrocarbons (PAHs) leading to decreased fecundity of females at adulthood was developed by building on existing qAOPs for (1) activation of the AHR leading to early …


Prescribed Fire Regimes Influence Responses Of Fungal And Bacterial Communities On New Litter Substrates In A Brackish Tidal Marsh, Viet Q. Dao, Crystal N. Johnson, William J. Platt Oct 2024

Prescribed Fire Regimes Influence Responses Of Fungal And Bacterial Communities On New Litter Substrates In A Brackish Tidal Marsh, Viet Q. Dao, Crystal N. Johnson, William J. Platt

Faculty Publications

Processes modifying newly deposited litter substrates should affect fine fuels in fire-managed tidal marsh ecosystems. Differences in chemical composition and dynamics of litter should arise from fire histories that generate pyrodiverse plant communities, tropical cyclones that deposit wrack as litter, tidal inundation that introduces and alters sediments and microbes, and interactions among these different processes. The resulting diversity and dynamics of available litter compounds should affect microbial (fungal and bacterial) communities and their roles in litter substrate dynamics and ecosystem responses over time. We experimentally examined effects of differences in litter types produced by different fire regimes and litter loads …


Regulation Of Bacterial Virulence Genes By Pecs Family Transcription Factors, George C. Nwokocha, Arpita Ghosh, Anne Grove Oct 2024

Regulation Of Bacterial Virulence Genes By Pecs Family Transcription Factors, George C. Nwokocha, Arpita Ghosh, Anne Grove

Faculty Publications

Bacterial plant pathogens adjust their gene expression programs in response to environmental signals and host-derived compounds. This ensures that virulence genes or genes encoding proteins, which promote bacterial fitness in a host environment, are expressed only when needed. Such regulation is in the purview of transcription factors, many of which belong to the ubiquitous multiple antibiotic resistance regulator (MarR) protein family. PecS proteins constitute a subset of this large protein family. PecS has likely been distributed by horizontal gene transfer, along with the divergently encoded efflux pump PecM, suggesting its integration into existing gene regulatory networks. Here, we discuss the …


Comparative Transcriptomic Analyses Reveal Differences In The Responses Of Diploid And Triploid Eastern Oysters To Environmental Stress, Rujuta V Vaidya, Sarah Bodenstein, Dildorakhon Rasulova, Jerome F La Peyre, Morgan W Kelly Oct 2024

Comparative Transcriptomic Analyses Reveal Differences In The Responses Of Diploid And Triploid Eastern Oysters To Environmental Stress, Rujuta V Vaidya, Sarah Bodenstein, Dildorakhon Rasulova, Jerome F La Peyre, Morgan W Kelly

Faculty Publications

Triploid oysters are commonly used as the basis for production in the aquaculture of eastern oysters along the USA East and Gulf of Mexico coasts. While they are valued for their rapid growth, incidents of triploid mortality during summer months have been well documented in eastern oysters, especially at low salinity sites. We compared global transcriptomic responses of diploid and triploid oysters bred from the same three maternal source populations at two different hatcheries and outplanted to a high (annual mean salinity = 19.4 ± 6.7) and low (annual mean salinity = 9.3 ± 5.0) salinity site. Oysters were sampled …


Macroevolution Of The Plant–Hummingbird Pollination System, Elisa Barreto, Mannfred M.A. Boehm, Ezgi Ogutcen, Stefan Abrahamczyk, Michael Kessler, Jordi Bascompte, Agnes S. Dellinger, Carolina Bello, D. Matthias Dehling, François Duchenne, Miriam Kaehler, Laura P. Lagomarsino, Lúcia G. Lohmann, María A. Maglianesi, Hélène Morlon, Nathan Muchhala, Juan Francisco Ornelas, Mathieu Perret, Nelson R. Salinas, Stacey D. Smith, Jana C. Vamosi, Isabela G. Varassin, Catherine H. Graham Oct 2024

Macroevolution Of The Plant–Hummingbird Pollination System, Elisa Barreto, Mannfred M.A. Boehm, Ezgi Ogutcen, Stefan Abrahamczyk, Michael Kessler, Jordi Bascompte, Agnes S. Dellinger, Carolina Bello, D. Matthias Dehling, François Duchenne, Miriam Kaehler, Laura P. Lagomarsino, Lúcia G. Lohmann, María A. Maglianesi, Hélène Morlon, Nathan Muchhala, Juan Francisco Ornelas, Mathieu Perret, Nelson R. Salinas, Stacey D. Smith, Jana C. Vamosi, Isabela G. Varassin, Catherine H. Graham

Faculty Publications

Plant–hummingbird interactions are considered a classic example of coevolution, a process in which mutually dependent species influence each other's evolution. Plants depend on hummingbirds for pollination, whereas hummingbirds rely on nectar for food. As a step towards understanding coevolution, this review focuses on the macroevolutionary consequences of plant–hummingbird interactions, a relatively underexplored area in the current literature. We synthesize prior studies, illustrating the origins and dynamics of hummingbird pollination across different angiosperm clades previously pollinated by insects (mostly bees), bats, and passerine birds. In some cases, the crown age of hummingbirds pre-dates the plants they pollinate. In other cases, plant …


Bicarbonate Is A Key Regulator But Not A Substrate For O2 Evolution In Photosystem Ii, David J. Vinyard, Govindjee Govindjee Oct 2024

Bicarbonate Is A Key Regulator But Not A Substrate For O2 Evolution In Photosystem Ii, David J. Vinyard, Govindjee Govindjee

Faculty Publications

Photosystem II (PSII) uses light energy to oxidize water and to reduce plastoquinone in the photosynthetic electron transport chain. O2 is produced as a byproduct. While most members of the PSII research community agree that O2 originates from water molecules, alternative hypotheses involving bicarbonate persist in the literature. In this perspective, we provide an overview of the important roles of bicarbonate in regulating PSII activity and assembly. Further, we emphasize that biochemistry, spectroscopy, and structural biology experiments have all failed to detect bicarbonate near the active site of O2 evolution. While thermodynamic arguments for oxygen-centered bicarbonate oxidation are valid, the …


Machine Learning For Automated Classification Of Lung Collagen In A Urethane-Induced Lung Injury Mouse Model, Khalid Hamad Alnafisah, Amit Ranjan, Sushant P. Sahu, Jianhua Chen, Sarah Mohammad Alhejji, Alexandra Noël, Manas Ranjan Gartia, Supratik Mukhopadhyay Oct 2024

Machine Learning For Automated Classification Of Lung Collagen In A Urethane-Induced Lung Injury Mouse Model, Khalid Hamad Alnafisah, Amit Ranjan, Sushant P. Sahu, Jianhua Chen, Sarah Mohammad Alhejji, Alexandra Noël, Manas Ranjan Gartia, Supratik Mukhopadhyay

Faculty Publications

Dysregulation of lung tissue collagen level plays a vital role in understanding how lung diseases progress. However, traditional scoring methods rely on manual histopathological examination introducing subjectivity and inconsistency into the assessment process. These methods are further hampered by inter-observer variability, lack of quantification, and their time-consuming nature. To mitigate these drawbacks, we propose a machine learning-driven framework for automated scoring of lung collagen content. Our study begins with the collection of a lung slide image dataset from adult female mice using second harmonic generation (SHG) microscopy. In our proposed approach, first, we manually extracted features based on the 46 …


In Situ Assembly Enabling Adhesive-Free Bonding Of Large Area Electronic Sensors To Concrete For Structural Health Monitoring, Emmanuel Ogunniyi, Han Liu, Austin Downey, Simon Laflamme, Caroline Bennett, William Collins, Hongki Jo, Paul Ziehl Oct 2024

In Situ Assembly Enabling Adhesive-Free Bonding Of Large Area Electronic Sensors To Concrete For Structural Health Monitoring, Emmanuel Ogunniyi, Han Liu, Austin Downey, Simon Laflamme, Caroline Bennett, William Collins, Hongki Jo, Paul Ziehl

Faculty Publications

Cracks developed in concrete infrastructure are one of the primary mechanisms that degrade their structural integrity, which may result in structural failures. Previous research on soft elastomeric capacitors (SEC) has shown their viability for structural health monitoring of structural materials, including concrete, steel, and fiberglass composites. The SEC, or its derivative version with a corrugated geometry termed corrugated SEC or cSEC, is a parallel plate capacitor. Prior work demonstrated that it was possible to directly paint the electrode interfacing with the structural material onto the structure and adhere the rest of the pre-fabricated sensor onto the wet interface, thereby eliminating …


Real-Time Synthesis Of A Nonuniformly Correlated, Partially Coherent Beam Using An Optical Coordinate Tansformation, Milo W. Hyde Iv Oct 2024

Real-Time Synthesis Of A Nonuniformly Correlated, Partially Coherent Beam Using An Optical Coordinate Tansformation, Milo W. Hyde Iv

Faculty Publications

We design, build, and validate an optical system for generating light beams with complex spatial coherence properties in real time. Beams of this type self-focus and are resistant to turbulence degradation, making them potentially useful in applications such as optical communications. We begin with a general theoretical analysis of our proposed design. Our approach starts by generating a Schell-model (uniformly correlated or shift-invariant) source by spatially filtering incoherent light. We then pass this light through an optical coordinate transformer, which converts the Schell-model source into a nonuniformly correlated field. After the general analysis, we discuss system engineering, including trade-offs among …


Return To Eden: God’S Design For Human Sexuality In The Song Of Songs, Richard M. Davidson Oct 2024

Return To Eden: God’S Design For Human Sexuality In The Song Of Songs, Richard M. Davidson

Faculty Publications

No abstract provided.