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High Male Sexual Investment As A Driver Of Extinction In Fossil Ostracods, Maria João Fernandes Martins, T. Markham Puckett, Rowan Lockwood, John P. Swaddle, Gene Hunt Apr 2018

High Male Sexual Investment As A Driver Of Extinction In Fossil Ostracods, Maria João Fernandes Martins, T. Markham Puckett, Rowan Lockwood, John P. Swaddle, Gene Hunt

Faculty Publications

Sexual selection favours traits that confer advantages in the competition for mates. In many cases, such traits are costly to produce and maintain, because the costs help to enforce the honesty of these signals and cues. Some evolutionary models predict that sexual selection also produces costs at the population level, which could limit the ability of populations to adapt to changing conditions and thus increase the risk of extinction. Other models, however, suggest that sexual selection should increase rates of adaptation and enhance the removal of deleterious mutations, thus protecting populations against extinction. Resolving the conflict between these models is …

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Energy Gradients Structure Microbial Communities Across Sediment Horizons In Deep Marine Sediments Of The South China Sea, Michael F. Graw, Grace D'Angelo, Matthew Borchers, Andrew R. Thurber, Joel E. Johnson, Chuanlun Zhang, Frederick S. Colwell Apr 2018

Energy Gradients Structure Microbial Communities Across Sediment Horizons In Deep Marine Sediments Of The South China Sea, Michael F. Graw, Grace D'Angelo, Matthew Borchers, Andrew R. Thurber, Joel E. Johnson, Chuanlun Zhang, Frederick S. Colwell

Faculty Publications

The deep marine subsurface is a heterogeneous environment in which the assembly of microbial communities is thought to be controlled by a combination of organic matter deposition, electron acceptor availability, and sedimentology. However, the relative importance of these factors in structuring microbial communities in marine sediments remains unclear. The South China Sea (SCS) experiences significant variability in sedimentation across the basin and features discrete changes in sedimentology as a result of episodic deposition of turbidites and volcanic ashes within lithogenic clays and siliceous or calcareous ooze deposits throughout the basin's history. Deep subsurface microbial communities were recently sampled by the …

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Corrigendum: Diatom Transcriptional And Physiological Responses To Changes In Iron Bioavailability Across Ocean Provinces [Front. Mar. Sci., 4, (2017), (360)] Doi: 10.3389/Fmars.2017.00360, Natalie R. Cohen, Kelsey A. Ellis, Robert H. Lampe, Heather Mcnair, Benjamin S. Twining, Maria T. Maldonado, Mark A. Brzezinski, Fedor I. Kuzminov, Kimberlee Thamatrakoln, Claire P. Till, Kenneth W. Bruland, William G. Sunda, Sibel Bargu, Adrian Marchetti Apr 2018

Corrigendum: Diatom Transcriptional And Physiological Responses To Changes In Iron Bioavailability Across Ocean Provinces [Front. Mar. Sci., 4, (2017), (360)] Doi: 10.3389/Fmars.2017.00360, Natalie R. Cohen, Kelsey A. Ellis, Robert H. Lampe, Heather Mcnair, Benjamin S. Twining, Maria T. Maldonado, Mark A. Brzezinski, Fedor I. Kuzminov, Kimberlee Thamatrakoln, Claire P. Till, Kenneth W. Bruland, William G. Sunda, Sibel Bargu, Adrian Marchetti

Faculty Publications

In the original Acknowledgments of this article, we neglected to thank Carolyn Duckham for her help collecting and processing samples for DIC uptake rates at stations C1-C3. The authors regret this oversight. This error does not change the scientific conclusions of the article in any way. The original article has been updated.

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A Computational Reconstruction Of Papio Phylogeny Using Alu Insertion Polymorphisms, Vallmer E. Jordan, Jerilyn A. Walker, Thomas O. Beckstrom, Cody J. Steely, Cullen L. Mcdaniel, Corey P. St Romain, Kim C. Worley, Jane Phillips-Conroy, Clifford J. Jolly, Jeffrey Rogers, Miriam K. Konkel, Mark A. Batzer, Jeffrey Rogers, R. Alan Harris, Muthuswamy Raveendran, Yue Liu, Shwetha Murali, Tauras P. Vilgalys, Jerilyn A. Walker, Miriam K. Konkel Apr 2018

A Computational Reconstruction Of Papio Phylogeny Using Alu Insertion Polymorphisms, Vallmer E. Jordan, Jerilyn A. Walker, Thomas O. Beckstrom, Cody J. Steely, Cullen L. Mcdaniel, Corey P. St Romain, Kim C. Worley, Jane Phillips-Conroy, Clifford J. Jolly, Jeffrey Rogers, Miriam K. Konkel, Mark A. Batzer, Jeffrey Rogers, R. Alan Harris, Muthuswamy Raveendran, Yue Liu, Shwetha Murali, Tauras P. Vilgalys, Jerilyn A. Walker, Miriam K. Konkel

Faculty Publications

© 2018 The Author(s). Background: Since the completion of the human genome project, the diversity of genome sequencing data produced for non-human primates has increased exponentially. Papio baboons are well-established biological models for studying human biology and evolution. Despite substantial interest in the evolution of Papio, the systematics of these species has been widely debated, and the evolutionary history of Papio diversity is not fully understood. Alu elements are primate-specific transposable elements with a well-documented mutation/insertion mechanism and the capacity for resolving controversial phylogenetic relationships. In this study, we conducted a whole genome analysis of Alu insertion polymorphisms unique to …

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Lyophilized Escherichia Coli-Based Cell-Free Systems For Robust, High-Density, Long-Term Storage, Mark Thomas Smith, Scott D. Berkheimer, Christopher J. Werner, Bradley Charles Bundy Apr 2018

Lyophilized Escherichia Coli-Based Cell-Free Systems For Robust, High-Density, Long-Term Storage, Mark Thomas Smith, Scott D. Berkheimer, Christopher J. Werner, Bradley Charles Bundy

Faculty Publications

Cell-free protein synthesis (CFPS) is a versatile tool for rapid recombinant protein production and engineering. One drawback of cell-free technology is the necessity to store the major components—cell extracts and energy systems—below freezing in bulky aqueous solutions. Here we describe simple methods for lyophilizing extracts and preparing powdered energy systems for CFPS. These techniques allow for high-density storage of cell-free systems that are more robust against temperature and bacterial degradation. Our methods have the potential to decrease storage expenses, allow for longer shelf-life of cell extracts at room temperature, and enable durable portable protein production technologies.

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Streamlined Extract Preparation For Escherichia Coli-Based Cell-Free Protein Synthesis By Sonication Or Bead Vortex Mixing, Prashanta Shrestha, Troy Michael Holland, Bradley Charles Bundy Apr 2018

Streamlined Extract Preparation For Escherichia Coli-Based Cell-Free Protein Synthesis By Sonication Or Bead Vortex Mixing, Prashanta Shrestha, Troy Michael Holland, Bradley Charles Bundy

Faculty Publications

Escherichia coli-based cell extract is a vital component of inexpensive and high-yielding cell-free protein synthesis reactions. However, effective preparation of E. coli cell extract is limited to high-pressure (French press-style or impinge-style) or bead mill homogenizers, which all require a significant capital investment. Here we report the viability of E. coli cell extract prepared using equipment that is both common to biotechnology laboratories and able to process small volume samples. Specifically, we assessed the low-capital-cost lysis techniques of: (i) sonication, (ii) bead vortex mixing, (iii) freeze-thaw cycling, and (iv) lysozyme …

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Blue And Black Cloth Targets: Effects Of Size, Shape, And Color On Stable Fly (Diptera: Muscidae) Attraction, Jerome A. Hogsette, Lane D. Foil Apr 2018

Blue And Black Cloth Targets: Effects Of Size, Shape, And Color On Stable Fly (Diptera: Muscidae) Attraction, Jerome A. Hogsette, Lane D. Foil

Faculty Publications

© 2018 Oxford University Press. All rights reserved. Stable fly management is challenging because of the fly's dispersal behavior and its tendency to remain on the host only while feeding. Optically attractive traps have been used to survey and sometimes reduce adult populations. Insecticide-treated blue and black cloth targets developed for tsetse fly management in Africa were found to be attractive to stable flies in the United States, and various evaluations were conducted in Louisiana and Florida. Tests using untreated targets were designed to answer questions about configuration, size, and color relative to efficacy and stability in high winds. Studies …

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Characterization Of Resistance To Cephus Cinctus (Hymenoptera: Cephidae) In Barley Germplasm, Andrea C. Varella, Luther E. Talbert, Buddhi B. Achhami, Nancy K. Blake, Megan L. Hofland, Jamie D. Sherman, Peggy F. Lamb, Gadi V.P. Reddy, David K. Weaver Apr 2018

Characterization Of Resistance To Cephus Cinctus (Hymenoptera: Cephidae) In Barley Germplasm, Andrea C. Varella, Luther E. Talbert, Buddhi B. Achhami, Nancy K. Blake, Megan L. Hofland, Jamie D. Sherman, Peggy F. Lamb, Gadi V.P. Reddy, David K. Weaver

Faculty Publications

Most barley cultivars have some degree of resistance to the wheat stem sawfly (WSS), Cephus cinctus Norton (Hymenoptera: Cephidae). Damage caused by WSS is currently observed in fields of barley grown in the Northern Great Plains, but the impact of WSS damage among cultivars due to genetic differences within the barley germplasm is not known. Specifically, little is known about the mechanisms underlying WSS resistance in barley. We characterized WSS resistance in a subset of the spring barley CAP (Coordinated Agricultural Project) germplasm panel containing 193 current and historically important breeding lines from six North American breeding programs. Panel lines …

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Social Recommendations For Personalized Fitness Assistance, Saumil Dharia, Magdalini Eirinaki, Vijesh Jain, Jvalant Patel, Iraklis Varlamis, Jainikkumar Vora, Rizen Yamauchi Apr 2018

Social Recommendations For Personalized Fitness Assistance, Saumil Dharia, Magdalini Eirinaki, Vijesh Jain, Jvalant Patel, Iraklis Varlamis, Jainikkumar Vora, Rizen Yamauchi

Faculty Publications

Wearable technology allows users to monitor their activity and pursue a healthy lifestyle through the use of embedded sensors. Such wearables usually connect to a mobile application that allows them to set their profile and keep track of their goals. However, due to the relatively “high maintenance” of such applications, where a significant amount of user feedback is expected, users who are very busy, or not as self-motivated, stop using them after a while. It has been shown that accountability improves commitment to an exercise routine. In this work, we present the PRO-Fit framework, a personalized fitness assistant aiming at …

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P3: Phylogenetic Posterior Prediction In Revbayes, Sebastian Höhna, Lyndon M. Coghill, Genevieve G. Mount, Robert C. Thomson, Jeremy M. Brown Apr 2018

P3: Phylogenetic Posterior Prediction In Revbayes, Sebastian Höhna, Lyndon M. Coghill, Genevieve G. Mount, Robert C. Thomson, Jeremy M. Brown

Faculty Publications

© The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. Tests of absolute model fit are crucial in model-based inference because poorly structured models can lead to biased parameter estimates. In Bayesian inference, posterior predictive simulations can be used to test absolute model fit. However, such tests have not been commonly practiced in phylogenetic inference due to a lack of convenient and flexible software. Here, we describe our newly implemented tests of model fit using posterior predictive testing, based on both data- and inference-based test statistics, in the phylogenetics software RevBayes. …

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Biogeography And Diversification Of Rhegmatorhina (Aves: Thamnophilidae): Implications For The Evolution Of Amazonian Landscapes During The Quaternary, Camila C. Ribas, Alexandre Aleixo, Chrysoula Gubili, Fernando M. D'Horta, Robb T. Brumfield, Joel Cracraft Apr 2018

Biogeography And Diversification Of Rhegmatorhina (Aves: Thamnophilidae): Implications For The Evolution Of Amazonian Landscapes During The Quaternary, Camila C. Ribas, Alexandre Aleixo, Chrysoula Gubili, Fernando M. D'Horta, Robb T. Brumfield, Joel Cracraft

Faculty Publications

© 2018 John Wiley & Sons Ltd Aim: To test the importance of alternative diversification drivers and biogeographical processes for the evolution of Amazonian upland forest birds through a densely sampled analysis of diversification of the endemic Amazonian genus Rhegmatorhina at multiple taxonomic and temporal scales. Location: Amazonia. Taxon: Antbirds (Thamnophilidae). Methods: We sequenced four mtDNA and nuclear gene regions of 120 individuals from 50 localities representing all recognized species and subspecies of the genus. We performed molecular phylogenetic analyses using both gene tree and species tree methods, molecular dating analysis and estimated population demographic history and gene flow. Results: …

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Biogeography And Diversification Of Rhegmatorhina (Aves: Thamnophilidae): Implications For The Evolution Of Amazonian Landscapes During The Quaternary, C C. Ribas, A Aleixo, C Gubili, F M. D'Horta, C C. Ribas, J Cracraft Apr 2018

Biogeography And Diversification Of Rhegmatorhina (Aves: Thamnophilidae): Implications For The Evolution Of Amazonian Landscapes During The Quaternary, C C. Ribas, A Aleixo, C Gubili, F M. D'Horta, C C. Ribas, J Cracraft

Faculty Publications

Aim: To test the importance of alternative diversification drivers and biogeographical processes for the evolution of Amazonian upland forest birds through a densely sampled analysis of diversification of the endemic Amazonian genus Rhegmatorhina at multiple taxonomic and temporal scales. Location: Amazonia. Taxon: Antbirds (Thamnophilidae). Methods: We sequenced four mtDNA and nuclear gene regions of 120 individuals from 50 localities representing all recognized species and subspecies of the genus. We performed molecular phylogenetic analyses using both gene tree and species tree methods, molecular dating analysis and estimated population demographic history and gene flow. Results: Dense sampling throughout the distribution of Rhegmatorhina …

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Endothelial Cell Autonomous Role Of Akt1, Monica Y. Lee, Ana Gamez-Mendez, Jiasheng Zhang, Zhenwu Zhuang, David J. Vinyard, Jan Kraehling, Heino Velazquez, Gary W. Brudvig, Themis R. Kyriakides, Michael Simons, William C. Sessa Apr 2018

Endothelial Cell Autonomous Role Of Akt1, Monica Y. Lee, Ana Gamez-Mendez, Jiasheng Zhang, Zhenwu Zhuang, David J. Vinyard, Jan Kraehling, Heino Velazquez, Gary W. Brudvig, Themis R. Kyriakides, Michael Simons, William C. Sessa

Faculty Publications

© 2018 American Heart Association, Inc. Objective - The importance of PI3K/Akt signaling in the vasculature has been demonstrated in several models, as global loss of Akt1 results in impaired postnatal ischemia- and VEGF-induced angiogenesis. The ubiquitous expression of Akt1, however, raises the possibility of cell-type-dependent Akt1-driven actions, thereby necessitating tissue-specific characterization. Approach and Results - Herein, we used an inducible, endothelial-specific Akt1-deleted adult mouse model (Akt1iECKO) to characterize the endothelial cell autonomous functions of Akt1 in the vascular system. Endothelial-targeted ablation of Akt1 reduces eNOS (endothelial nitric oxide synthase) phosphorylation and promotes both increased vascular contractility in isolated vessels …

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Global Environmental Change Effects On Plant Community Composition Trajectories Depend Upon Management Legacies, Michael P. Perring, Markus Bernhardt-Römermann, Lander Baeten, Gabriele Midolo, Haben Blondeel, Leen Depauw, Dries Landuyt, Sybryn L. Maes, Emiel De Lombaerde, Maria Mercedes Carón, Mark Vellend, Jörg Brunet, Markéta Chudomelová, Guillaume Decocq, Martin Diekmann, Thomas Dirnböck, Inken Dörfler, Tomasz Durak, Pieter De Frenne, Frank S. Gilliam, Radim Hédl, Thilo Heinken, Patrick Hommel, Bogdan Jaroszewicz, Keith J. Kirby, Martin Kopecký, Jonathan Lenoir, Daijiang Li, František Máliš, Fraser J.G. Mitchell, Tobias Naaf, Miles Newman, Petr Petřík Apr 2018

Global Environmental Change Effects On Plant Community Composition Trajectories Depend Upon Management Legacies, Michael P. Perring, Markus Bernhardt-Römermann, Lander Baeten, Gabriele Midolo, Haben Blondeel, Leen Depauw, Dries Landuyt, Sybryn L. Maes, Emiel De Lombaerde, Maria Mercedes Carón, Mark Vellend, Jörg Brunet, Markéta Chudomelová, Guillaume Decocq, Martin Diekmann, Thomas Dirnböck, Inken Dörfler, Tomasz Durak, Pieter De Frenne, Frank S. Gilliam, Radim Hédl, Thilo Heinken, Patrick Hommel, Bogdan Jaroszewicz, Keith J. Kirby, Martin Kopecký, Jonathan Lenoir, Daijiang Li, František Máliš, Fraser J.G. Mitchell, Tobias Naaf, Miles Newman, Petr Petřík

Faculty Publications

© 2017 John Wiley & Sons Ltd The contemporary state of functional traits and species richness in plant communities depends on legacy effects of past disturbances. Whether temporal responses of community properties to current environmental changes are altered by such legacies is, however, unknown. We expect global environmental changes to interact with land-use legacies given different community trajectories initiated by prior management, and subsequent responses to altered resources and conditions. We tested this expectation for species richness and functional traits using 1814 survey-resurvey plot pairs of understorey communities from 40 European temperate forest datasets, syntheses of management transitions since the …

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Rice Phyllosphere Bacillus Species And Their Secreted Metabolites Suppress Aspergillus Flavus Growth And Aflatoxin Production In Vitro And In Maize Seeds, Subbaiah Chalivendra, Catherine Derobertis, Jorge Reyes Pineda, Jong Hyun Ham, Kenneth Damann Apr 2018

Rice Phyllosphere Bacillus Species And Their Secreted Metabolites Suppress Aspergillus Flavus Growth And Aflatoxin Production In Vitro And In Maize Seeds, Subbaiah Chalivendra, Catherine Derobertis, Jorge Reyes Pineda, Jong Hyun Ham, Kenneth Damann

Faculty Publications

The emergence of super-toxigenic strains by recombination is a risk from an intensive use of intraspecific aflatoxin (AF) biocontrol agents (BCAs). Periodical alternation with interspecific-BCAs will be safer since they preclude recombination. We are developing an AF-biocontrol system using rice-associated Bacilli reported previously (RABs). More than 50% of RABs inhibited the growth of multiple A. flavus strains, with RAB4R being the most inhibitory and RAB1 among the least. The fungistatic activity of RAB4R is associated with the lysis of A. flavus hyphal tips. In field trails with the top five fungistatic RABs, RAB4R consistently inhibited AF contamination of maize by …

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Potential Biopesticides For Crucifer Flea Beetle, Phyllotreta Cruciferae (Coleoptera: Chrysomelidae) Management Under Dryland Canola Production In Montana, Shabeg Singh Briar, Frank Antwi, Govinda Shrestha, Anamika Sharma, Gadi V.P. Reddy Apr 2018

Potential Biopesticides For Crucifer Flea Beetle, Phyllotreta Cruciferae (Coleoptera: Chrysomelidae) Management Under Dryland Canola Production In Montana, Shabeg Singh Briar, Frank Antwi, Govinda Shrestha, Anamika Sharma, Gadi V.P. Reddy

Faculty Publications

The crucifer flea beetle, Phyllotreta cruciferae (Goeze), is an economically important and dominant pest of canola (Brassica napus L) in the Northern Great Plains of the USA. The current flea beetle management strategy is based on using synthetic chemical treated seeds and if necessary, foliar spray of chemicals at canola seedlings in early spring for targeting adult population. However, there is an increasing demand for development of alternative management strategies for P. cruciferae pertaining to concerns over the development of resistance to synthetic insecticides and non-target effects on pollinators and other beneficial insects. Replicated field trials were conducted to test …

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Stem Cell Factor In Combination With Granulocyte Colony-Stimulating Factor Reduces Cerebral Capillary Thrombosis In A Mouse Model Of Cadasil, Suning Ping, Xuecheng Qiu, Maria E. Gonzalez-Toledo, Xiaoyun Liu, Li Ru Zhao Apr 2018

Stem Cell Factor In Combination With Granulocyte Colony-Stimulating Factor Reduces Cerebral Capillary Thrombosis In A Mouse Model Of Cadasil, Suning Ping, Xuecheng Qiu, Maria E. Gonzalez-Toledo, Xiaoyun Liu, Li Ru Zhao

Faculty Publications

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is a cerebral small vascular disease caused by NOTCH3 mutation-induced vascular smooth muscle cell (VSMC) degeneration, leading to ischemic stroke and vascular dementia. Our previous study has demonstrated that repeated treatment with a combination of stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF) reduces VSMC degeneration and cerebral endothelial cell (EC) damage and improves cognitive function in a mouse model of CADASIL (TgNotch3R90C). This study aimed to determine whether cerebral thrombosis occurs in TgNotch3R90C mice and whether repeated SCF+G-CSF treatment reduces cerebral thrombosis in TgNotch3R90C mice. Using the approaches …

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Race-Ethnicity, Union Status, And Change In Body Mass Index In Young Adulthood, Rhiannon A. Kroeger, Reanne Frank Apr 2018

Race-Ethnicity, Union Status, And Change In Body Mass Index In Young Adulthood, Rhiannon A. Kroeger, Reanne Frank

Faculty Publications

This study used data from three waves of the National Longitudinal Study of Adolescent to Adult Health and fixed effects regression to consider whether associations between change in union status and change in body mass index (BMI) were moderated by race-ethnicity. The results indicated that intimate unions were differentially associated with gains in BMI along racial-ethnic lines, especially for women. When compared with White women, marriage was associated with larger increases in BMI for Black, Hispanic, and Multiracial women, and cohabitation was associated with larger increases for Black and Hispanic women. In contrast, marriage and cohabitation were associated with less …

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P62 As A Therapeutic Target For Inhibition Of Autophagy In Prostate Cancer, Lei Wang, Donghern Kim, James T.F. Wise, Xianglin Shi, Zhuo Zhang, Robert S. Dipaola Apr 2018

P62 As A Therapeutic Target For Inhibition Of Autophagy In Prostate Cancer, Lei Wang, Donghern Kim, James T.F. Wise, Xianglin Shi, Zhuo Zhang, Robert S. Dipaola

Faculty Publications

Background: To test the hypothesis that p62 is an optimal target for autophagy inhibition and Verteporfin, a clinically available drug approved by FDA to treat macular degeneration that inhibits autophagy by targeting p62 protein, can be developed clinically to improve therapy for advanced prostate cancer. Methods: Forced expression of p62 in PC-3 cells and normal prostate epithelial cells, RWPE-1 and PZ-HPV7, were carried out by transfection of these cells with pcDNA3.1/p62 or p62 shRNA plasmid. Autophagosomes and autophagic flux were measured by transfection of tandem fluorescence protein mCherry-GFP-LC3 construct. Apoptosis was measured by Annexin V/PI staining. Tumorigenesis was measured by …

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A Teachable Moment: The Relevance Of Ethics And The Limits Of Science, Brian F. Snyder, Linda M. Hooper-Bui Apr 2018

A Teachable Moment: The Relevance Of Ethics And The Limits Of Science, Brian F. Snyder, Linda M. Hooper-Bui

Faculty Publications

No abstract provided.

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Coupled Effects Of Oil Spill And Hurricane On Saltmarsh Terrestrial Arthropods, Wokil Bam, Linda M. Hooper-Bui, Rachel M. Strecker, Puspa L. Adhikari, Edward B. Overton Apr 2018

Coupled Effects Of Oil Spill And Hurricane On Saltmarsh Terrestrial Arthropods, Wokil Bam, Linda M. Hooper-Bui, Rachel M. Strecker, Puspa L. Adhikari, Edward B. Overton

Faculty Publications

Terrestrial arthropods play an important role in saltmarsh ecosystems, mainly affecting the saltmarsh’s primary production as the main consumers of terrestrial primary production and decomposition. Some of these arthropods, including selected insects and spiders, can be used as ecological indicators of overall marsh environmental health, as they are differentially sensitive to ecological stressors, such as land loss, erosion, oil spills, and tropical storms. In the present study, we used terrestrial arthropods collected from seven (three lightly-oiled, four heavily-oiled) sites in Barataria Bay and from three unoiled reference sites in Delacroix, Louisiana, to determine the impacts of the distribution and re-distribution …

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Emerging Roles For The Nucleolus 2017, Susan J. Baserga, Patrick J. Dimario Apr 2018

Emerging Roles For The Nucleolus 2017, Susan J. Baserga, Patrick J. Dimario

Faculty Publications

No abstract provided.

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Reference Dependence Of The Two-Determinant Coupled-Cluster Method For Triplet And Open-Shell Singlet States Of Biradical Molecules, Jesse J. Lutz, Marcel Nooijen, Ajith Perera, Rodney J. Bartlett Apr 2018

Reference Dependence Of The Two-Determinant Coupled-Cluster Method For Triplet And Open-Shell Singlet States Of Biradical Molecules, Jesse J. Lutz, Marcel Nooijen, Ajith Perera, Rodney J. Bartlett

Faculty Publications

We study the performance of the two-determinant (TD) coupled-cluster (CC) method which, unlike conventional ground-state single-reference (SR) CC methods, can, in principle, provide a naturally spin-adapted treatment of the lowest-lying open-shell singlet (OSS) and triplet electronic states. Various choices for the TD-CC reference orbitals are considered, including those generated by the multi-configurational self-consistent field method. Comparisons are made with the results of high-level SR-CC, equation-of-motion (EOM) CC, and multi-reference EOM calculations performed on a large test set of over 100 molecules with low-lying OSS states. It is shown that in cases where the EOMCC reference function is poorly described, TD-CC …

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Holocene Vegetation And Climate Evolution Of Corpus Christi And Trinity Bays: Implications On Coastal Texas Source-To-Sink Deposition, Shannon Ferguson, Sophie Warny, John B. Anderson, Alexander R. Simms, Gilles Escarguel Apr 2018

Holocene Vegetation And Climate Evolution Of Corpus Christi And Trinity Bays: Implications On Coastal Texas Source-To-Sink Deposition, Shannon Ferguson, Sophie Warny, John B. Anderson, Alexander R. Simms, Gilles Escarguel

Faculty Publications

© 2018 The Texas coastline stretches 595 km across almost 4° of latitude and is home to diverse coastal vegetation assemblages, yet only a handful of studies have documented the climate and vegetative change of this region through the Holocene. We provide a detailed palynological record of Holocene climate for coastal Texas, based upon three subaqueous sediment cores from Corpus Christi Bay and Trinity Bay. Cluster analysis and correspondence analysis were used to investigate changes in palynological assemblages through time within each core. Common to both bays are nonarboreal taxa including Asteraceae (mainly Ambrosia and Helianthus), Chenopodium, Poaceae, and arboreal …

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Editing Life: Modern Biology And Biblical Principles, Peter J. Lyons Apr 2018

Editing Life: Modern Biology And Biblical Principles, Peter J. Lyons

Faculty Publications

No abstract provided.

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How Subterranean Regulation Hinders Innovation In Assisted Reproductive Technology, Myrisha S. Lewis Apr 2018

How Subterranean Regulation Hinders Innovation In Assisted Reproductive Technology, Myrisha S. Lewis

Faculty Publications

Most scholars believe assisted reproductive technology is subject only to minimal regulation, especially by the federal government. This belief, I contend, is wrong. In this Article, I examine agency documents, statements by officials, and letters that the U.S. Food and Drug Administration (FDA) has sent to physicians and researchers over the past fifteen years to reveal an overlooked regulatory program. The FDA has been targeting new forms of assisted reproductive technology that involve small genetic modifications (advanced assisted reproductive technologies or AARTs) through regulatory actions that receive little public, media, or scholarly attention. I term this method of regulation “subterranean …

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Ict Women Professionals' Perceptions Of Workplace Ethical Problems: A Quantitative Survey, Yeslam Al-Saggaf, Kim M. Thompson Apr 2018

Ict Women Professionals' Perceptions Of Workplace Ethical Problems: A Quantitative Survey, Yeslam Al-Saggaf, Kim M. Thompson

Faculty Publications

Which ethical problems are most frequently experienced by ICT women professionals? Which ethical problems experienced by ICT women professionals are of most concern to them as individuals? A quantitative survey of 2,315 Australian ICT professionals of whom 15.4 percent were females revealed that the top 15 most frequently faced ethical problems that the females identified were nearly identical to those identified by males. Of these 15 problems, five were judged to affect females personally. These are overworking staff, blaming others for own mistakes, bullying, unprofessional behavior, and discrimination. Of these five problems, gender only predicted three problems that affect females …

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Silica-Conjugated Polymer Hybrid Fluorescent Nanoparticles: Preparation By Surface-Initiated Polymerization And Spectroscopic Studies, Sourav Chatterjee, Tony E. Karam, Cornelia Rosu, Chun Han Wang, Sang Gil Youm, Xin Li, Changwoo Do, Yaroslav Losovyj, Paul S. Russo, Louis H. Haber, Evgueni E. Nesterov Mar 2018

Silica-Conjugated Polymer Hybrid Fluorescent Nanoparticles: Preparation By Surface-Initiated Polymerization And Spectroscopic Studies, Sourav Chatterjee, Tony E. Karam, Cornelia Rosu, Chun Han Wang, Sang Gil Youm, Xin Li, Changwoo Do, Yaroslav Losovyj, Paul S. Russo, Louis H. Haber, Evgueni E. Nesterov

Faculty Publications

© 2018 American Chemical Society. Organic/inorganic hybrid nanoscale materials possess fascinating optical, electronic, magnetic, and catalytic properties that are promising for a variety of practical applications. Such properties can be dramatically affected by the hierarchical structure and molecular organization in the nanomaterials. Herein, we employed surface-initiated Kumada catalyst-transfer polymerization to prepare hybrid materials consisting of shells of conjugated polymers (CPs) - polythiophene or poly(p-phenylene) - and their block copolymers covalently attached to the surface of silica nanoparticles. Because of the controlled chain-growth mechanism of surface-initiated polymerization, we obtained structurally well-defined CP blocks in the diblock copolymer shells, which produced distinct …

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A Plant-Produced Vaccine Protects Mice Against Lethal West Nile Virus Infection Without Enhancing Zika Or Dengue Virus Infectivity, Huafang Lai, Amber M. Paul, Haiyan Sun, Junyun He, Ming Yang, Fengwei Bai Mar 2018

A Plant-Produced Vaccine Protects Mice Against Lethal West Nile Virus Infection Without Enhancing Zika Or Dengue Virus Infectivity, Huafang Lai, Amber M. Paul, Haiyan Sun, Junyun He, Ming Yang, Fengwei Bai

Faculty Publications

West Nile virus (WNV) has caused multiple global outbreaks with increased frequency of neuroinvasive disease in recent years. Despite many years of research, there are no licensed therapeutics or vaccines available for human use. One of the major impediments of vaccine development against WNV is the potential enhancement of infection by related flaviviruses in vaccinated subjects through the mechanism of antibody-dependent enhancement of infection (ADE). For instance, the recent finding of enhancement of Zika virus (ZIKV) infection by pre-exposure to WNV further complicates the development of WNV vaccines. Epidemics of WNV and the potential risk of ADE by current vaccine …

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A Single Fungal Map Kinase Controls Plant Cell-To-Cell Invasion By The Rice Blast Fungus, Wasin Sakulkoo, Miriam Osés-Ruiz, Ely Oliveira Garcia, Darren M. Soanes, George R. Littlejohn, Christian Hacker, Ana Correia, Barbara Valent, Nicholas J. Talbot Mar 2018

A Single Fungal Map Kinase Controls Plant Cell-To-Cell Invasion By The Rice Blast Fungus, Wasin Sakulkoo, Miriam Osés-Ruiz, Ely Oliveira Garcia, Darren M. Soanes, George R. Littlejohn, Christian Hacker, Ana Correia, Barbara Valent, Nicholas J. Talbot

Faculty Publications

Blast disease destroys up to 30% of the rice crop annually and threatens global food security. The blast fungus Magnaporthe oryzae invades plant tissue with hyphae that proliferate and grow from cell to cell, often through pit fields, where plasmodesmata cluster. We showed that chemical genetic inhibition of a single fungal mitogen-activated protein (MAP) kinase, Pmk1, prevents M. oryzae from infecting adjacent plant cells, leaving the fungus trapped within a single plant cell. Pmk1 regulates expression of secreted fungal effector proteins implicated in suppression of host immune defenses, preventing reactive oxygen species generation and excessive callose deposition at plasmodesmata. Furthermore, …

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