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Micrat: A Novel Algorithm For Inferring Gene Regulatory Networks Using Time Series Gene Expression Data, Bei Yang, Yaohui Xu, Andrew Maxwell, Wonryull Koh, Ping Gong, Chaoyang Zhang Dec 2018

Micrat: A Novel Algorithm For Inferring Gene Regulatory Networks Using Time Series Gene Expression Data, Bei Yang, Yaohui Xu, Andrew Maxwell, Wonryull Koh, Ping Gong, Chaoyang Zhang

Faculty Publications

Background: Reconstruction of gene regulatory networks (GRNs), also known as reverse engineering of GRNs, aims to infer the potential regulation relationships between genes. With the development of biotechnology, such as gene chip microarray and RNA-sequencing, the high-throughput data generated provide us with more opportunities to infer the gene-gene interaction relationships using gene expression data and hence understand the underlying mechanism of biological processes. Gene regulatory networks are known to exhibit a multiplicity of interaction mechanisms which include functional and non-functional, and linear and non-linear relationships. Meanwhile, the regulatory interactions between genes and gene products are not spontaneous since various …


Selective Electrocatalytic Reduction Of Co2 Into Co At Small, Thiol-Capped Au/Cu Nanoparticles, Douglas R. Kauffman, Dominic R. Alfonso, De Nyago Tafen, Congjun Wang, Yunyun Zhou, Yang Yu, Jonathan W. Lekse, Xingyi Deng, Vanessa Espinoza, Jamie Trindell, Oshadha K. Ranasingha, Amitava Roy, Jun Sik Lee, Huolin L. Xin Dec 2018

Selective Electrocatalytic Reduction Of Co2 Into Co At Small, Thiol-Capped Au/Cu Nanoparticles, Douglas R. Kauffman, Dominic R. Alfonso, De Nyago Tafen, Congjun Wang, Yunyun Zhou, Yang Yu, Jonathan W. Lekse, Xingyi Deng, Vanessa Espinoza, Jamie Trindell, Oshadha K. Ranasingha, Amitava Roy, Jun Sik Lee, Huolin L. Xin

Faculty Publications

The electrochemical CO reduction reaction (CO RR) is a promising approach for converting fossil fuel emissions into environmentally sustainable chemicals and fuels. The ability to control the surface structure of CO RR nanocatalysts provides an opportunity to tune product selectivity. Bimetallic gold-copper catalysts have been identified as emerging electrocatalyst candidates, but Cu incorporation typically lowers product selectivity compared with pure Au. Here we show sustained CO selectivity and activity up to 49% Cu content in small (<2 >nm), thiol-capped Au/Cu nanoparticles (NPs). Bimetallic NPs containing 49% Cu selectivity converted CO into CO with 100 ± 6% CO Faradaic efficiency and …


Selective Electrocatalytic Reduction Of Co2 Into Co At Small, Thiol-Capped Au/Cu Nanoparticles, Douglas R. Kauffman, Dominic R. Alfonso, De Nyago Tafen, Congjun Wang, Yunyun Zhou, Yang Yu, Jonathan W. Lekse, Xingyi Deng, Vanessa Espinoza, Jamie Trindell, Oshadha K. Ranasingha, Amitava Roy, Jun Sik Lee, Huolin L. Xin Dec 2018

Selective Electrocatalytic Reduction Of Co2 Into Co At Small, Thiol-Capped Au/Cu Nanoparticles, Douglas R. Kauffman, Dominic R. Alfonso, De Nyago Tafen, Congjun Wang, Yunyun Zhou, Yang Yu, Jonathan W. Lekse, Xingyi Deng, Vanessa Espinoza, Jamie Trindell, Oshadha K. Ranasingha, Amitava Roy, Jun Sik Lee, Huolin L. Xin

Faculty Publications

The electrochemical CO reduction reaction (CO RR) is a promising approach for converting fossil fuel emissions into environmentally sustainable chemicals and fuels. The ability to control the surface structure of CO RR nanocatalysts provides an opportunity to tune product selectivity. Bimetallic gold-copper catalysts have been identified as emerging electrocatalyst candidates, but Cu incorporation typically lowers product selectivity compared with pure Au. Here we show sustained CO selectivity and activity up to 49% Cu content in small (<2 >nm), thiol-capped Au/Cu nanoparticles (NPs). Bimetallic NPs containing 49% Cu selectivity converted CO into CO with 100 ± 6% CO Faradaic efficiency and …


Rhizosphere Microbial Communities Of Spartina Alternifloa And Juncus Roemerianus From Restored And Natural Tidal Marshes On Deer Island, Mississippi, Olga Mavrodi, Carina M. Jung, Jed O. Eberly, Samuel Hendry, Sanchirmaa Namijilsuren, Patrick D. Biber, Karl J. Indest, Dmitri V. Mavrodi Dec 2018

Rhizosphere Microbial Communities Of Spartina Alternifloa And Juncus Roemerianus From Restored And Natural Tidal Marshes On Deer Island, Mississippi, Olga Mavrodi, Carina M. Jung, Jed O. Eberly, Samuel Hendry, Sanchirmaa Namijilsuren, Patrick D. Biber, Karl J. Indest, Dmitri V. Mavrodi

Faculty Publications

The U. S. Gulf of Mexico is experiencing a dramatic increase in tidal marsh restoration actions, which involves planting coastal areas with smooth cordgrass (Spartina alterniflora) and black needlerush (Juncus roemerianus) for erosion control and to provide habitat for fish and wildlife. It can take decades for sedimentary cycles in restored marshes to approach reference conditions, and the contribution of the sediment microbial communities to these processes is poorly elucidated. In this study, we addressed this gap by comparing rhizosphere microbiomes of S. alterniflora and J. roemerianus from two restored marshes and a natural reference marsh located at Deer Island, …


Mammal Collections Of The Western Hemisphere: A Survey And Directory Of Collections, Jonathan L. Dunnum, Bryan S. Mclean, Robert C. Dowler, Sergio Ticul Alvarez-Castañeda, Jeff E. Bradley, Robert D. Bradley, Leslie N. Carraway, Juan P. Carrera-E, Christopher J. Conroy, Brandi S. Coyner, John R. Demboski, Carl W. Dick, Kate Doyle, Jacob A. Esselstyn, Eliecer Gutiérrez, John D. Hanson, Paula M. Holahan, Thorvald Holmes, Carlos A. Iudica, Rafael N. Leite, Thomas E. Lee, Burton K. Lim, Jason L. Malaney, Suzanne B. Mclaren, Nancy D. Moncrief, Link Olson, Nicte Ordóñez-Garza, Caleb D. Phillips, Marcia A. Revelez, Eric A. Rickart, Duke S. Rogers, Cody W. Thompson, Nathan S. Upham Dec 2018

Mammal Collections Of The Western Hemisphere: A Survey And Directory Of Collections, Jonathan L. Dunnum, Bryan S. Mclean, Robert C. Dowler, Sergio Ticul Alvarez-Castañeda, Jeff E. Bradley, Robert D. Bradley, Leslie N. Carraway, Juan P. Carrera-E, Christopher J. Conroy, Brandi S. Coyner, John R. Demboski, Carl W. Dick, Kate Doyle, Jacob A. Esselstyn, Eliecer Gutiérrez, John D. Hanson, Paula M. Holahan, Thorvald Holmes, Carlos A. Iudica, Rafael N. Leite, Thomas E. Lee, Burton K. Lim, Jason L. Malaney, Suzanne B. Mclaren, Nancy D. Moncrief, Link Olson, Nicte Ordóñez-Garza, Caleb D. Phillips, Marcia A. Revelez, Eric A. Rickart, Duke S. Rogers, Cody W. Thompson, Nathan S. Upham

Faculty Publications

As a periodic assessment of the mammal collection resource, the Systematic Collections Committee (SCC) of the American Society of Mammalogists undertakes decadal surveys of the collections held in the Western Hemisphere. The SCC surveyed 429 collections and compiled a directory of 395 active collections containing 5,275,155 catalogued specimens. Over the past decade, 43 collections have been lost or transferred and 38 new or unsurveyed collections were added. Growth in number of total specimens, expansion of genomic resource collections, and substantial gains in digitization and web accessibility were documented, as well as slight shifts in proportional representation of taxonomic groups owing …


Homogenization Of Species Composition And Species Association Networks Are Decoupled, Daijiang Li, Timothée Poisot, Donald M. Waller, Benjamin Baiser Dec 2018

Homogenization Of Species Composition And Species Association Networks Are Decoupled, Daijiang Li, Timothée Poisot, Donald M. Waller, Benjamin Baiser

Faculty Publications

© 2018 John Wiley & Sons Ltd Aim: Ecological communities are composed of both species and the biotic relationships (interactions or spatial associations) among them. Biotic homogenization in species composition (i.e., increased site-to-site similarity) is recognized as a common consequence of global change, but less is known about how the similarity of species relationships changes over space and time. Does homogenization of species composition lead to homogenization of species relationships or are the dynamics of species relationships decoupled from changes in species composition?. Location: Wisconsin, USA. Time period: 1950–2012. Major taxa studied: Vascular plants. Methods: We used long-term resurvey data …


Gauging Support For Macroecological Patterns In Helminth Parasites, Tad A. Dallas, A. Alonso Aguirre, Sarah Budischak, Colin Carlson, Vanessa Ezenwa, Barbara Han, Shan Huang, Patrick R. Stephens Dec 2018

Gauging Support For Macroecological Patterns In Helminth Parasites, Tad A. Dallas, A. Alonso Aguirre, Sarah Budischak, Colin Carlson, Vanessa Ezenwa, Barbara Han, Shan Huang, Patrick R. Stephens

Faculty Publications

© 2018 John Wiley & Sons Ltd Aim: To explore spatial patterns of helminth parasite diversity, and to investigate three main macroecological patterns – (a) latitude–diversity relationships, (b) positive scaling between parasite and host diversity, and (c) species–area relationships – using a largely underutilized global database of helminth parasite occurrence records. Location: Global. Methods: We examined the London Natural History Museum’s collection of helminth parasite occurrence records, consisting of over 18,000 unique host species and 27,000 unique helminth parasite species distributed across over 350 distinct terrestrial and aquatic localities. Results: We find support for latitudinal gradients in parasite diversity and …


Alternative Polyadenylation Drives Genome-To-Phenome Information Detours In The Ampkα1 And Ampkα2 Knockout Mice, Shuwen Zhang, Yangzi Zhang, Xiang Zhou, Xing Fu, Jennifer J. Michal, Guoli Ji, Min Du, Jon F. Davis, Zhihua Jiang Dec 2018

Alternative Polyadenylation Drives Genome-To-Phenome Information Detours In The Ampkα1 And Ampkα2 Knockout Mice, Shuwen Zhang, Yangzi Zhang, Xiang Zhou, Xing Fu, Jennifer J. Michal, Guoli Ji, Min Du, Jon F. Davis, Zhihua Jiang

Faculty Publications

© 2018 The Author(s). Currently available mouse knockout (KO) lines remain largely uncharacterized for genome-to-phenome (G2P) information flows. Here we test our hypothesis that altered myogenesis seen in AMPKα1- and AMPKα2-KO mice is caused by use of alternative polyadenylation sites (APSs). AMPKα1 and AMPKα2 are two α subunits of adenosine monophosphate-activated protein kinase (AMPK), which serves as a cellular sensor in regulation of many biological events. A total of 56,483 APSs were derived from gastrocnemius muscles. The differentially expressed APSs (DE-APSs) that were down-regulated tended to be distal. The DE-APSs that were related to reduced and increased muscle mass were …


Optimizing Photorespiration For Improved Crop Productivity, Paul F. South, Amanda P. Cavanagh, Patricia E. Lopez-Calcagno, Christine A. Raines, Donald R. Ort Dec 2018

Optimizing Photorespiration For Improved Crop Productivity, Paul F. South, Amanda P. Cavanagh, Patricia E. Lopez-Calcagno, Christine A. Raines, Donald R. Ort

Faculty Publications

© 2018 Institute of Botany, Chinese Academy of Sciences In C3 plants, photorespiration is an energy-expensive process, including the oxygenation of ribulose-1,5-bisphosphate (RuBP) by ribulose 1,5-bisphosphate carboxylase/oxygenase (Rubisco) and the ensuing multi-organellar photorespiratory pathway required to recycle the toxic byproducts and recapture a portion of the fixed carbon. Photorespiration significantly impacts crop productivity through reducing yields in C3 crops by as much as 50% under severe conditions. Thus, reducing the flux through, or improving the efficiency of photorespiration has the potential of large improvements in C3 crop productivity. Here, we review an array of approaches intended to engineer photorespiration in …


Challenges During Diapause And Anhydrobiosis: Mitochondrial Bioenergetics And Desiccation Tolerance, Steven C. Hand, Daniel S. Moore, Yuvraj Patil Dec 2018

Challenges During Diapause And Anhydrobiosis: Mitochondrial Bioenergetics And Desiccation Tolerance, Steven C. Hand, Daniel S. Moore, Yuvraj Patil

Faculty Publications

© 2018 International Union of Biochemistry and Molecular Biology In preparation for the onset of environmental challenges like overwintering, food limitation, anoxia, or water stress, many invertebrates and certain killifish enter diapause. Diapause is a developmentally-programed dormancy characterized by suppression of development and metabolism. For embryos of Artemia franciscana (brine shrimp), the metabolic arrest is profound. These gastrula-stage embryos depress oxidative metabolism by ~99% during diapause and survive years of severe desiccation in a state termed anhydrobiosis. Trehalose is the sole fuel source for this developmental stage. Mitochondrial function during diapause is downregulated primarily by restricting substrate supply, as a …


Habitat Suitability Estimated By Niche Models Is Largely Unrelated To Species Abundance, Tad A. Dallas, Alan Hastings Dec 2018

Habitat Suitability Estimated By Niche Models Is Largely Unrelated To Species Abundance, Tad A. Dallas, Alan Hastings

Faculty Publications

© 2018 John Wiley & Sons Ltd Aim: Data on species occurrences are far more common than data on species abundances. However, a central goal of large-scale ecology is to understand the spatial distribution of abundance. It has been proposed that species distribution models trained on species occurrence records may capture variation in species abundance. Here, we gauge support for relationships between species abundance and predicted climatic suitability from species distribution models, and relate the slope of this relationship to species traits, evolutionary relationships and sampling completeness. Location: USA. Time period: 1658–2017. Major taxa studied: Mammal and tree species. Methods, …


Large-Scale Computational Drug Repositioning To Find Treatments For Rare Diseases, Rajiv Gandhi Govindaraj, Misagh Naderi, Manali Singha, Jeffrey Lemoine, Michal Brylinski Dec 2018

Large-Scale Computational Drug Repositioning To Find Treatments For Rare Diseases, Rajiv Gandhi Govindaraj, Misagh Naderi, Manali Singha, Jeffrey Lemoine, Michal Brylinski

Faculty Publications

© 2018, The Author(s). Rare, or orphan, diseases are conditions afflicting a small subset of people in a population. Although these disorders collectively pose significant health care problems, drug companies require government incentives to develop drugs for rare diseases due to extremely limited individual markets. Computer-aided drug repositioning, i.e., finding new indications for existing drugs, is a cheaper and faster alternative to traditional drug discovery offering a promising venue for orphan drug research. Structure-based matching of drug-binding pockets is among the most promising computational techniques to inform drug repositioning. In order to find new targets for known drugs ultimately leading …


Multidimensional Relationships Of Herbicides With Insect-Crop Food Webs, Anamika Sharma, Prashant Jha, Gadi V.P. Reddy Dec 2018

Multidimensional Relationships Of Herbicides With Insect-Crop Food Webs, Anamika Sharma, Prashant Jha, Gadi V.P. Reddy

Faculty Publications

Controlling weeds is critical for improving the yield and quality of crops. Herbicides are the most commonly applied pesticides in agro-ecosystems. Herbicides affect insects directly as contact damage and indirectly by influencing food supplies. The innate susceptibility, life stages, and mode of feeding of insects can affect the herbicide–insect interaction. Interaction of herbicides with insect pest and beneficial insects is mainly indirect and absence of weeds either can reduce the insect population or causes switching of host plant and hence can also increase the population. The direct effect of herbicides depends on carrier or surfactant used. Presence of herbicides also …


Adoption Of Sustainable Agriculture Practices Among Farmers In Kentucky, Usa, Bijesh Mishra, Buddhi R. Gyawali, Krishna P. Paudel, Neelam C. Poudyal, Marion F. Simon, Siddhartha Dasgupta, George Antonious Dec 2018

Adoption Of Sustainable Agriculture Practices Among Farmers In Kentucky, Usa, Bijesh Mishra, Buddhi R. Gyawali, Krishna P. Paudel, Neelam C. Poudyal, Marion F. Simon, Siddhartha Dasgupta, George Antonious

Faculty Publications

© 2018, Springer Science+Business Media, LLC, part of Springer Nature. Promoting the sustainable agricultural practices at an individual farm level is essential to ensure agricultural sustainability. This study analyzed whether and how various factors related to farm or farmers’ characteristics influence the adoption intensity of sustainable agriculture practices. We used a negative binomial regression model to fit the data collected from a mail survey of farmers in Kentucky, USA. Our results showed that the adoption intensity of sustainable agriculture practices varied significantly among agricultural districts in Kentucky. Farmers who grew row crops, had irrigation facilities, and were in favor of …


Dissolved Carbon Transport In A River-Lake Continuum: A Case Study In A Subtropical Watershed, Usa, Zhen Xu, Y. Jun Xu Dec 2018

Dissolved Carbon Transport In A River-Lake Continuum: A Case Study In A Subtropical Watershed, Usa, Zhen Xu, Y. Jun Xu

Faculty Publications

Rivers and lakes have been traditionally studied as separate entities for carbon transport. However, there is a gap in our knowledge of the connectivity of dissolved carbon in a river-lake continuum. In this study, we analyzed dissolved carbon along the Little River-Catahoula Lake in subtropical Louisiana, United States to assess carbon biogeochemistry in such a river-lake continuum. Monthly in-situ measurements and water sample collections were made at four locations during April 2015 to February 2016 to determine riverine carbon transport into and out of the lake. Results show that much of the dissolved inorganic carbon (DIC) in the river-lake continuum …


Gobbling Activity Of Eastern Wild Turkeys Relative To Male Movements And Female Nesting Phenology In South Carolina, Michael J. Chamberlain, Patrick H. Wightman, Bradley S. Cohen, Bret A. Collier Dec 2018

Gobbling Activity Of Eastern Wild Turkeys Relative To Male Movements And Female Nesting Phenology In South Carolina, Michael J. Chamberlain, Patrick H. Wightman, Bradley S. Cohen, Bret A. Collier

Faculty Publications

Wild turkeys (Meleagris gallopavo) use a polygynous mating system, and males must balance fitness benefits of courtship displays against costs of their reproductive strategies. Wild turkeys are the only gamebird species in the contiguous United States hunted primarily during their reproductive period. Managers attempt to implement seasons that allow for hunter satisfaction while limiting effects to reproduction and ensuring sustainable populations. To minimize illegal harvest, managers often attempt to set spring hunting seasons when gobbling activity is high and females are actively incubating nests. Gobbling activity varies significantly both temporally and spatially, and relationships between gobbling activity and reproductive phenology …


Genome-Wide Discovery Of Dna Polymorphisms By Whole Genome Sequencing Differentiates Weedy And Cultivated Rice, Chenglin Chai, Rama Shankar, Mukesh Jain, Prasanta K. Subudhi Dec 2018

Genome-Wide Discovery Of Dna Polymorphisms By Whole Genome Sequencing Differentiates Weedy And Cultivated Rice, Chenglin Chai, Rama Shankar, Mukesh Jain, Prasanta K. Subudhi

Faculty Publications

Analyzing the genome level DNA polymorphisms between weedy and cultivated rice is crucial to elucidate the molecular basis of weedy and agronomic traits, which in turn can enhance our ability to control weedy rice and its utilization for rice improvement. Here, we presented the genome-wide genetic variations between a weedy rice accession PSRR-1 and two cultivated rice accessions, Bengal and Nona Bokra, belonging to japonica and indica subspecies, respectively. The total number of SNPs and InDels in PSRR/Bengal was similar to that of Nona Bokra/Bengal, but was three times greater than that of PSRR/Nona Bokra. There were 11546 large-effect SNPs/InDels …


Effect Of Surrounding Vegetation On Microbial Survival Or Die-Off On Watermelon Surface In An Agriculture Setting, Vijay Singh Chhetri, Kathryn Fontenot, Ronald Strahan, Veerachandra K. Yemmireddy, Katheryn J. Parraga Estrada, Achyut Adhikari Dec 2018

Effect Of Surrounding Vegetation On Microbial Survival Or Die-Off On Watermelon Surface In An Agriculture Setting, Vijay Singh Chhetri, Kathryn Fontenot, Ronald Strahan, Veerachandra K. Yemmireddy, Katheryn J. Parraga Estrada, Achyut Adhikari

Faculty Publications

Preharvest contamination of produce with food borne pathogens has been a major food safety issue. In this study, we investigated the effect of surrounding vegetation on the survival of natural and inoculated generic Escherichia coli on watermelon rinds in an agricultural field setting. There was no significant difference (p >.05) on the populations of natural generic E. coli (1–1.46 log Most Probable Number (MPN)/sample) and coliforms (<3.99 log CFU/cm2) on watermelons harvested from low, medium, and high levels of vegetation. However, the survival rate of generic E. coli inoculated on watermelon rind discs was variable with the level of vegetation. A significant reduction in generic E. coli count was observed within 12 hr at all vegetation levels. After 108 hr, discs placed at low vegetation level had a highest die-off reduction (3 log Colony Forming Units (CFU)/cm2) compared to medium and high vegetation levels. Practical applications: To ensure preharvest produce safety, the Food Safety Modernization Act (FSMA) produce safety rule has suggested a time interval between last irrigation and harvest for potentially contaminating microorganisms to die-off. However, a knowledge gap exists regarding the influence of surrounding vegetation on microbial die-off rates on produce in the agricultural field. The findings of this study emphasize the importance of considering the surrounding vegetation while making decisions for developing preharvest risk management strategies based on microbial die-off rate calculations.


Development Of Nanocomposite Adsorbents For Heavy Metal Removal From Wastewater, Bin Wang, Tingting Wu, Subramania Angaiah, Vignesh Murugadoss, Jong Eun Ryu, Evan K. Wujcik, Na Lu, David P. Young, Qiang Gao, Zhanhu Guo Dec 2018

Development Of Nanocomposite Adsorbents For Heavy Metal Removal From Wastewater, Bin Wang, Tingting Wu, Subramania Angaiah, Vignesh Murugadoss, Jong Eun Ryu, Evan K. Wujcik, Na Lu, David P. Young, Qiang Gao, Zhanhu Guo

Faculty Publications

Development of highly efficient, low cost adsorbents for heavy metal ion removal from wastewater is an enduring undertaking. Two major groups of nanocomposite adsorbents are reviewed here. The magnetic carbon family is first discussed including the preparation of such materials. Various carbon sources have been used in the preparation, and the structural characteristics have been analyzed. Cr(VI) removal studies unveil a wide range of performance. The second group adsorbents is polymer functionalized nanocomposites. One notable polymer is polyaniline which is a redox polymer. The redox nature allows the composite materials to facilitate Cr(VI) reduction to Cr(III) which is prone to …


Editorial Introduction For The Topical Issue "The New Metaphysics: Analytic/Continental Crossovers", Paul Livingston, Jon Cogburn Dec 2018

Editorial Introduction For The Topical Issue "The New Metaphysics: Analytic/Continental Crossovers", Paul Livingston, Jon Cogburn

Faculty Publications

No abstract provided.


Understanding Fear Of Zika: Personal, Interpersonal, And Media Influences, Chun Yang, James Price Dillard, Ruobing Li Dec 2018

Understanding Fear Of Zika: Personal, Interpersonal, And Media Influences, Chun Yang, James Price Dillard, Ruobing Li

Faculty Publications

Fear of infectious disease often motivates people to protect themselves. But, it can also produce negative bio-social-psychological effects whose severity is on par with those of the disease. The WHO declaration of Zika as a world health crisis presented an opportunity to study factors that bring about fear. Beginning nine days after the WHO announcement, data were gathered from women aged 18–35 living in the southern United States (N = 719). Respondents reported experiencing fear of Zika at levels akin to those reported following other significant crises/disasters (e.g., the terrorist attacks of 9/11). Fear increased as a function of (1) …


Superior Memory: An Example Of The Benefits Of Examining Individual Differences In Cognitive Psychology, Lawrence Patihis Dec 2018

Superior Memory: An Example Of The Benefits Of Examining Individual Differences In Cognitive Psychology, Lawrence Patihis

Faculty Publications

Comments on an article by Robert Logie (see record 2018-64362-002). Author agrees with Logie that there is potentially much to be gained now from cognitive psychology research that investigates individual differences. Author would add the caveat, and Logie alludes to this too, that the traditional approach of comparing experimental conditions has been more productive than any other and has led to useful general theories (and descriptions of cognitive phenomena) in the areas of perception, attention, memory, and reasoning. Research with experimental-condition comparisons utilizing random assignment has revolutionized psychology and brought a well-rounded understanding of the mind that far surpassed …


Taxon-Specific Aerosolization Of Bacteria And Viruses In An Experimental Ocean-Atmosphere Mesocosm, Jennifer M. Michaud, Luke R. Thompson, Drishti Kaul, Josh L. Espinoza, R. Alexander Richter, Zhenjiang Zech Xu, Christopher Lee, Kevin M. Pham, Charlotte M. Beall, Francesca Malfatti, Farooq Azam, Rob Knight, Michael D. Burkart, Christopher L. Dupont, Kimberly A. Prather Dec 2018

Taxon-Specific Aerosolization Of Bacteria And Viruses In An Experimental Ocean-Atmosphere Mesocosm, Jennifer M. Michaud, Luke R. Thompson, Drishti Kaul, Josh L. Espinoza, R. Alexander Richter, Zhenjiang Zech Xu, Christopher Lee, Kevin M. Pham, Charlotte M. Beall, Francesca Malfatti, Farooq Azam, Rob Knight, Michael D. Burkart, Christopher L. Dupont, Kimberly A. Prather

Faculty Publications

Ocean-derived, airborne microbes play important roles in Earth’s climate system and human health, yet little is known about factors controlling their transfer from the ocean to the atmosphere. Here, we study microbiomes of isolated sea spray aerosol (SSA) collected in a unique ocean–atmosphere facility and demonstrate taxon-specific aerosolization of bacteria and viruses. These trends are conserved within taxonomic orders and classes, and temporal variation in aerosolization is similarly shared by related taxa. We observe enhanced transfer into SSA of Actinobacteria, certain Gammaproteobacteria, and lipid-enveloped viruses; conversely, Flavobacteriia, some Alphaproteobacteria, and Caudovirales are generally under-represented in SSA. Viruses do not transfer …


Multiple Environmental Stressors Induce Complex Transcriptomic Responses Indicative Of Phenotypic Outcomes In Western Fence Lizard, Kurt A. Gust, Vijender Chaitankar, Preetam Ghosh, Mitchell S. Wilbanks, Xianfeng Chen, Natalie D. Barker, Don Pham, Leona D. Scanlan, Arun Rawat, Larry G. Talent, Michael J. Quinn Jr., Christopher D. Vulpe, Mohamed O. Elasri, Mark S. Johnson, Edward J. Perkins, Craig A. Mcfarland Dec 2018

Multiple Environmental Stressors Induce Complex Transcriptomic Responses Indicative Of Phenotypic Outcomes In Western Fence Lizard, Kurt A. Gust, Vijender Chaitankar, Preetam Ghosh, Mitchell S. Wilbanks, Xianfeng Chen, Natalie D. Barker, Don Pham, Leona D. Scanlan, Arun Rawat, Larry G. Talent, Michael J. Quinn Jr., Christopher D. Vulpe, Mohamed O. Elasri, Mark S. Johnson, Edward J. Perkins, Craig A. Mcfarland

Faculty Publications

Background

The health and resilience of species in natural environments is increasingly challenged by complex anthropogenic stressor combinations including climate change, habitat encroachment, and chemical contamination. To better understand impacts of these stressors we examined the individual- and combined-stressor impacts of malaria infection, food limitation, and 2,4,6-trinitrotoluene (TNT) exposures on gene expression in livers of Western fence lizards (WFL, Sceloporus occidentalis) using custom WFL transcriptome-based microarrays.

Results

Computational analysis including annotation enrichment and correlation analysis identified putative functional mechanisms linking transcript expression and toxicological phenotypes. TNT exposure increased transcript expression for genes involved in erythropoiesis, potentially in response to …


Halted Innovation: The Expansion Of Federal Jurisdiction Over Medicine And The Human Body, Myrisha S. Lewis Dec 2018

Halted Innovation: The Expansion Of Federal Jurisdiction Over Medicine And The Human Body, Myrisha S. Lewis

Faculty Publications

Modern medical innovations are blurring the line between medical practice and medical devices and drugs. Historically, many techniques have been developed in medicine, without any interference from the federal government, as medical practice is (and has historically been) an area of state jurisdiction. Over the past two decades, however, the U.S. Food and Drug Administration (FDA) has been exerting jurisdiction over the human body and the practice of medicine by targeting new medical techniques for oversight and subjecting the continued use of those treatments to onerous and legally questionable regulatory requirements that hinder the use of those treatments in practice. …


Introduction To The French Geotraces North Atlantic Transect (Ga01): Geovide Cruise, Géraldine Sarthou, Pascale Lherminier, Eric P. Achterberg, Fernando Alonso-Pérez, Eva Bucciarelli, Julia Boutorh, Vincent Bouvier, Edward A. Boyle, Pierre Branellec, Lidia I. Carracedo, Nuria Casacuberta, Maxi Castrillejo, Marie Cheize, Leonardo Contreira Pereira, Daniel Cossa, Nathalie Daniault, Emmanuel De Saint-Léger, Frank Dehairs, Feifei Deng, Floriane Desprez De Gésincourt, Jérémy Devesa, Lorna Foliot, Debany Fonseca-Batista, Morgane Gallinari, Maribel I. Garciá-Ibáñez, Arthur Gourain, Emilie Grossteffan, Michel Hamon, Lars Eric Heimbürger, Gideon M. Henderson, Catherine Jeandel, Catherine Kermabon, François Lacan Nov 2018

Introduction To The French Geotraces North Atlantic Transect (Ga01): Geovide Cruise, Géraldine Sarthou, Pascale Lherminier, Eric P. Achterberg, Fernando Alonso-Pérez, Eva Bucciarelli, Julia Boutorh, Vincent Bouvier, Edward A. Boyle, Pierre Branellec, Lidia I. Carracedo, Nuria Casacuberta, Maxi Castrillejo, Marie Cheize, Leonardo Contreira Pereira, Daniel Cossa, Nathalie Daniault, Emmanuel De Saint-Léger, Frank Dehairs, Feifei Deng, Floriane Desprez De Gésincourt, Jérémy Devesa, Lorna Foliot, Debany Fonseca-Batista, Morgane Gallinari, Maribel I. Garciá-Ibáñez, Arthur Gourain, Emilie Grossteffan, Michel Hamon, Lars Eric Heimbürger, Gideon M. Henderson, Catherine Jeandel, Catherine Kermabon, François Lacan

Faculty Publications

© 2018 Author(s). The GEOVIDE cruise, a collaborative project within the framework of the international GEOTRACES programme, was conducted along the French-led section in the North Atlantic Ocean (Section GA01), between 15 May and 30 June 2014. In this special issue (https://www.biogeosciences.net/special-issue900.html), results from GEOVIDE, including physical oceanography and trace element and isotope cyclings, are presented among 18 articles. Here, the scientific context, project objectives, and scientific strategy of GEOVIDE are provided, along with an overview of the main results from the articles published in the special issue.


Remote Sensing Of Sargassum Biomass, Nutrients, And Pigments, Mengqiu Wang, Chuanmin Hu, Jennifer Cannizzaro, David English, Xingxing Han, David Naar, Brian Lapointe, Rachel Brewton, Frank J. Hernandez Jr. Nov 2018

Remote Sensing Of Sargassum Biomass, Nutrients, And Pigments, Mengqiu Wang, Chuanmin Hu, Jennifer Cannizzaro, David English, Xingxing Han, David Naar, Brian Lapointe, Rachel Brewton, Frank J. Hernandez Jr.

Faculty Publications

ield and laboratory experiments are designed to measure Sargassum biomass per area (density), surface reflectance, nutrient contents, and pigment concentrations. An Alternative Floating Algae Index (AFAI)‐biomass density model is established to link the spectral reflectance to Sargassum biomass density, with a relative uncertainty of ~ 12%. Monthly mean integrated Sargassum biomass in the Caribbean Sea and Central West Atlantic reached at least 4.4 million tons in July 2015. The average % C, % N, and % P per dry‐weight are 27.16, 1.06, and 0.10, respectively. The mean chlorophyll‐a (Chl‐a) concentration is ~ 0.05% of the dry‐weight. With these parameters, the …


Microbial Processes In The Weathering Crust Aquifer Of A Temperate Glacier, Brent C. Christner, Heather F. Lavender, Christina L. Davis, Erin E. Oliver, Sarah U. Neuhaus, Krista F. Myers, Birgit Hagedorn, Slawek M. Tulaczyk, Peter T. Doran, William C. Stone Nov 2018

Microbial Processes In The Weathering Crust Aquifer Of A Temperate Glacier, Brent C. Christner, Heather F. Lavender, Christina L. Davis, Erin E. Oliver, Sarah U. Neuhaus, Krista F. Myers, Birgit Hagedorn, Slawek M. Tulaczyk, Peter T. Doran, William C. Stone

Faculty Publications

© 2018 Author(s). Incident solar radiation absorbed within the ablation zone of glaciers generates a shallow perched aquifer and seasonal icebound microbial habitat. During the melt seasons of 2014 and 2015, borehole investigations were used to examine the physical, geochemical, and microbiological properties in the near-surface ice and aquifer of the temperate Matanuska Glacier (south-central Alaska). Based on temperature, solar forcing, and ice optical properties, the dissipation of shortwave radiation promoted internal melting and the formation of a weathering crust with a maximum depth of ∼2 m. Boreholes into the weathering crust provided access to water percolating through the porous …


Sexually-Relevant Visual And Chemosensory Signals Induce Distinct Behaviors And Neural Activation Patterns In The Social African Cichlid, Astatotilapia Burtoni, Karen E. Field, Christopher T. Mcvicker, Karen P. Maruska Nov 2018

Sexually-Relevant Visual And Chemosensory Signals Induce Distinct Behaviors And Neural Activation Patterns In The Social African Cichlid, Astatotilapia Burtoni, Karen E. Field, Christopher T. Mcvicker, Karen P. Maruska

Faculty Publications

© 2018 Field, McVicker and Maruska. Across vertebrates, the use of multimodal (multiple sensory modalities) signals has evolved to convey important information to receivers. Information content of multimodal signals can be the same as or different from information in each unimodal signal, and are classified as redundant or non-redundant, respectively, based on receivers’ behavioral responses. Despite the prevalence and importance of multimodal signaling across taxa, relatively little is known about how and where these signals are processed in the brains of receivers. We used the social African cichlid fish, Astatotilapia burtoni, to investigate how sexually-relevant visual and chemosensory uni- and …


Sequence Pattern Mining With Variables, James S. Okolica, Gilbert L. Peterson, Robert F. Mills, Michael R. Grimaila Nov 2018

Sequence Pattern Mining With Variables, James S. Okolica, Gilbert L. Peterson, Robert F. Mills, Michael R. Grimaila

Faculty Publications

Sequence pattern mining (SPM) seeks to find multiple items that commonly occur together in a specific order. One common assumption is that all of the relevant differences between items are captured through creating distinct items, e.g., if color matters then the same item in two different colors would have two items created, one for each color. In some domains, that is unrealistic. This paper makes two contributions. The first extends SPM algorithms to allow item differentiation through attribute variables for domains with large numbers of items, e.g, by having one item with a variable with a color attribute rather than …