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Commons-Based Digital Libraries, Anita Coleman Mar 2006

Commons-Based Digital Libraries, Anita Coleman

Faculty Publications

This is a presentation of 30 slides at the Brown Bag Series, School of Library and Information Science, Indiana University, Bloomington, Indiana on 31 March 2006. Abstract: Commons-based digital libraries are an emerging phenomenon. They are based on a new vision of digital information organization and use. A definition of commons-based digital libraries, some examples, fundamental characteristics, emerging information behaviors, and preliminary results from a scholarly communication survey of LIS faculty will be presented.


Better Health Statistics: The Cuban Experience [9], Mariana Lazo, Manuel Franco, Richard Cooper, Pedro Orduñez Mar 2006

Better Health Statistics: The Cuban Experience [9], Mariana Lazo, Manuel Franco, Richard Cooper, Pedro Orduñez

Faculty Publications

No abstract provided.


Racially-Tailored’ Medicine Unraveled, Sharona Hoffman Mar 2006

Racially-Tailored’ Medicine Unraveled, Sharona Hoffman

Faculty Publications

In June 2005, the FDA approved BiDil, a heart failure medication that is labeled for use only by African-Americans and thus is the first treatment of its kind. The drug likely portends a future of growing interest in "race-based" medicine. This phenomenon is emerging at the same time that scientists, in light of the Human Genome Project, are reaching an understanding that "race" has no biological meaning, and consequently, "racially-tailored" medicine is both puzzling and troubling.

This Article explores the reasons for the new focus on "racial-profiling" in medicine. It analyzes the risks and dangers of this approach, including medical …


Responders’ Responsibility: Liability And Immunity In Public Health Emergencies, Sharona Hoffman Mar 2006

Responders’ Responsibility: Liability And Immunity In Public Health Emergencies, Sharona Hoffman

Faculty Publications

Many experts predict the advent of a public health emergency resulting from a flu pandemic or bioterrorism attack in the foreseeable future. At the same time, many health care providers express significant concern about liability arising from emergency response activities, because it is unlikely that they would be able to provide optimal care in crisis conditions. They also state that this concern will likely influence their willingness to be involved in response activities. This article addresses issues that have received little attention in the legal literature: liability and immunity in public health emergencies. The article provides a first-of-its-kind comprehensive analysis …


Multigenre-Multigendered Research Papers, Mary E. Styslinger Mar 2006

Multigenre-Multigendered Research Papers, Mary E. Styslinger

Faculty Publications

Mary E. Styslinger asked high school seniors to explore genre and gender in a nontraditional research project. She then “sought to discover more about what students knew and how students’ knowing was represented.” Her analysis reveals that the multigenre paper can be a powerful form that allows for complexity, questioning, and the development of personal voice.


A Fractional Dispersion Model For Overland Solute Transport, Zhi Qiang Deng, João L.M.P. De Lima, M. Isabel P. De Lima, Vijay P. Singh Mar 2006

A Fractional Dispersion Model For Overland Solute Transport, Zhi Qiang Deng, João L.M.P. De Lima, M. Isabel P. De Lima, Vijay P. Singh

Faculty Publications

Using the kinematic-wave overland flow equation and a fractional dispersion-advection equation, a process-oriented, physically-based model is developed for overland solute transport. Two scenarios, one consisting of downslope and the other of upslope rainstorm movements, are considered for numerical computations. Under these conditions, the hydrograph displays a long-tailed distribution due to the variation in flow velocity in both time and distance. The solute transport exhibits a complex behavior. Pollutographs are characterized by a steep rising limb, with a peak, and a long, stretched receding limb; whereas the solute concentration distributions feature a rapid receding limb followed by a long stretched rising …


Colleges Explore Funding For Electronic Course Media, Susie Quartey, Copyright Clearance Center Mar 2006

Colleges Explore Funding For Electronic Course Media, Susie Quartey, Copyright Clearance Center

Faculty Publications

How to fund course materials for students is widely debated by campus administrators. This brief article interviews three copyright officials at different academic institutions who provide insight as to how electronic course materials are funded on their campuses and future funding options to be explored.


Ethics And E-Medicine, Jessica Wilen Berg Feb 2006

Ethics And E-Medicine, Jessica Wilen Berg

Faculty Publications

The computer revolution has had enormous effect on all aspects of the practice of medicine from scheduling and billing, to treatments, to research and beyond. This article focuses on the impact of new internet technologies on relationships between physicians and patients. These forms e-medicine may be utilized outside the confines of a pre-existing relationship, and thus have the potential to replace rather than merely augment traditional medical care. They change the setting and nature of the physician-patient relationship and thereby alter how medicine is practiced.

Initial discussions of this issue implied that e-medicine was problematic because it failed to create …


The Comet Assay To Determine The Mode Of Cell Death For The Ultrasonic Delivery Of Doxorubicin To Human Leukemia (Hl-60 Cells) From Pluronic P105 Micelles, Ghaleb A. Husseini, Kim L. O'Neill, William G. Pitt Feb 2006

The Comet Assay To Determine The Mode Of Cell Death For The Ultrasonic Delivery Of Doxorubicin To Human Leukemia (Hl-60 Cells) From Pluronic P105 Micelles, Ghaleb A. Husseini, Kim L. O'Neill, William G. Pitt

Faculty Publications

This notes examines the mode of cell death of HL-60 cells exposed to 70 kHz and 1.3 W/cm2 in the presence of 1% Pluronic P105 and 1.67 μg/ml doxorubicin (Dox). The cells were ultrasonicated for 30, 60 and 120 minutes. They were then lysed, electrophorised, stained using propidium iodide, and their DNA profile captured using a fluorescent microscope. The gradual DNA damage observed and the comet tails captured after 1 and 2 hours of insonation suggest that the mode of cell killing is apoptosis.


Rising Expectations In Business Education, Annette M. Nellen, Marlene E. Turner Feb 2006

Rising Expectations In Business Education, Annette M. Nellen, Marlene E. Turner

Faculty Publications

The article comments on the rising expectations in business education. It explains the term liberal education. It mentions the Liberal Education & America's Promise Campaign launched by the Association of American Colleges & Universities in 2005. The article also notes that integrative learning is particularly relevant because it melds students' professional and liberal educations.


Trehalose Uptake Through P2x7 Purinergic Channels Provides Dehydration Protection, Gloria D. Elliott, Xiang Hong Liu, Jennifer L. Cusick, Michael Menze, Jill Vincent, Trudy Witt, Steve Hand, Mehmet Toner Feb 2006

Trehalose Uptake Through P2x7 Purinergic Channels Provides Dehydration Protection, Gloria D. Elliott, Xiang Hong Liu, Jennifer L. Cusick, Michael Menze, Jill Vincent, Trudy Witt, Steve Hand, Mehmet Toner

Faculty Publications

The tetra-anionic form of ATP (ATP4-) is known to induce monovalent and divalent ion fluxes in cells that express purinergic P2X 7 receptors and with sustained application of ATP it has been shown that dyes as large as 831 Da can permeate the cell membrane. The current study explores the kinetics of loading α,α-trehalose (342 Da) into ATP stimulated J774.A1 cells, which are known to express the purinergic P2X 7 receptor. Cells that were incubated at 37°C in a 50 mM phosphate buffer (pH 7.0) containing 225 mM trehalose and 5 mM ATP, were shown to load trehalose linearly over …


The Prp19 U-Box Crystal Structure Suggests A Common Dimeric Architecture For A Class Of Oligomeric E3 Ubiquitin Ligases, Craig W. Vander Kooi, Melanie D. Ohi, Joshua A. Rosenberg, Michael L. Oldham, Marcia E. Newcomer, Kathleen L. Gould, Walter J. Chazin Jan 2006

The Prp19 U-Box Crystal Structure Suggests A Common Dimeric Architecture For A Class Of Oligomeric E3 Ubiquitin Ligases, Craig W. Vander Kooi, Melanie D. Ohi, Joshua A. Rosenberg, Michael L. Oldham, Marcia E. Newcomer, Kathleen L. Gould, Walter J. Chazin

Faculty Publications

Prp19 is an essential splicing factor and a member of the U-box family of E3 ubiquitin ligases. Prp19 forms a tetramer via a central coiled-coil domain. Here, we show the U-box domain of Prp19 exists as a dimer within the context of the Prp19 tetramer. A high-resolution structure of the homodimeric state of the Prp19 U-box was determined by X-ray crystallography. Mutation of the U-box dimer interface abrogates U-box dimer formation and is lethal in vivo. The structure of the U-box dimer enables construction of a complete model of Prp19 providing insights into how the tetrameric protein functions as an …


The Magnificence Of The Disaster: Reconstructing The Sony Bmg Rootkit Incident, Deirdre Mulligan, Aaron K. Perzanowski Jan 2006

The Magnificence Of The Disaster: Reconstructing The Sony Bmg Rootkit Incident, Deirdre Mulligan, Aaron K. Perzanowski

Faculty Publications

Late in 2005, Sony BMG released millions of Compact Discs containing digital rights management technologies that threatened the security of its customers' computers and the integrity of the information infrastructure more broadly. This Article aims to identify the market, technological, and legal factors that appear to have led a presumably rational actor toward a strategy that in retrospect appears obviously and fundamentally misguided.

The Article first addresses the market-based rationales that likely influenced Sony BMG's deployment of these DRM systems and reveals that even the most charitable interpretation of Sony BMG's internal strategizing demonstrates a failure to adequately value security …


Historical Perspectives On Attitudes Concerning Death And Dying, David San Filippo Ph.D. Jan 2006

Historical Perspectives On Attitudes Concerning Death And Dying, David San Filippo Ph.D.

Faculty Publications

Beliefs and practices concerning death have changed throughout human history. In pre-modern times, death at a young age was common due to living conditions and medical practices. As medical science has advanced and helped humans live longer, attitudes and responses to death also have changed. In modern Western societies, death is often ignored or feared. Changes in lifestyles and improved medical science have depersonalized death and made it an encroachment on life instead of part of life. This has left many people ill equipped to deal with death when it touches their lives.


The Value Of The Awareness Of Near-Death Experiences, David San Filippo Ph.D. Jan 2006

The Value Of The Awareness Of Near-Death Experiences, David San Filippo Ph.D.

Faculty Publications

A principal value of Near-death experiences may be in the telling of the stories and the effect these stories have for others to reduce their fears of and concerns about death. This E-book explores the impact and value knowing about, not having a near-death experience has on those who have heard, watch, or read reports of this phenomenon.


Justificación, Sanación Y Responsabilidad, Guillermo C. Hansen Jan 2006

Justificación, Sanación Y Responsabilidad, Guillermo C. Hansen

Faculty Publications

No abstract provided.


God In Civil Society: Prophetic, Sapiential, And Pacific, Gary M. Simpson Jan 2006

God In Civil Society: Prophetic, Sapiential, And Pacific, Gary M. Simpson

Faculty Publications

No abstract provided.


‘Flex Your Power’: Energy Crises And The Shifting Rhetoric Of The Grid, Anne Marie Todd, A. Wood Jan 2006

‘Flex Your Power’: Energy Crises And The Shifting Rhetoric Of The Grid, Anne Marie Todd, A. Wood

Faculty Publications

In response to widespread power outages, rolling blackouts, and ubiquitous energy debates, this essay considers our relation to energy and the grid that produces it. First, we investigate California's multimedia Flex Your Power campaign, which defines consumers as nodes of the grid to emphasize their responsibility to maintain a stable energy supply. Second, we examine state and national responses to the 2003 blackout in the Northeastern United States, attending to three strategies through which grid administrators sought to impose order, enact hierarchy, and deindividuate power. We propose that the grid invokes personalization at the "local" level and abstraction at the …


"I Am The Truth": An Understanding Of Truth From Christology For Scripture, Alan G. Padgett Jan 2006

"I Am The Truth": An Understanding Of Truth From Christology For Scripture, Alan G. Padgett

Faculty Publications

No abstract provided.


Heparin Modulates The 99-Loop Of Factor Ixa: Effects On Reactivity With Isolated Kunitz-Type Inhibitor Domains, Pierre F. Neuenschwander, Stephen R. Williamson, Armen Nalian, Kimberly J. Baker-Deadmond Jan 2006

Heparin Modulates The 99-Loop Of Factor Ixa: Effects On Reactivity With Isolated Kunitz-Type Inhibitor Domains, Pierre F. Neuenschwander, Stephen R. Williamson, Armen Nalian, Kimberly J. Baker-Deadmond

Faculty Publications

Reactivity of factor IXa with basic pancreatic trypsin inhibitor is enhanced by low molecular weight heparin (enoxaparin). Previous studies by us have suggested that this effect involves allosteric modulation of factor IXa. We examined the reactivity of factor IXa with several isolated Kunitz-type inhibitor domains: basic pancreatic trypsin inhibitor, the Kunitz inhibitor domain of protease Nexin-2, and the first two inhibitor domains of tissue factor pathway inhibitor. We find that enhancement of factor IXa reactivity by enoxaparin is greatest for basic pancreatic trypsin inhibitor (>10-fold), followed by the second tissue factor pathway inhibitor domain (1.7-fold) and the Kunitz inhibitor …


The Rotavirus Enterotoxin Nsp4 Directly Interacts With The Caveolar Structural Protein Caveolin-1, Rebecca D. Parr, Stephen M. Storey, Deanne M. Mitchell, Avery Mcintosh, Minglong Zhou, Kiran D. Mir, Judith M. Ball Jan 2006

The Rotavirus Enterotoxin Nsp4 Directly Interacts With The Caveolar Structural Protein Caveolin-1, Rebecca D. Parr, Stephen M. Storey, Deanne M. Mitchell, Avery Mcintosh, Minglong Zhou, Kiran D. Mir, Judith M. Ball

Faculty Publications

Rotavirus nonstructural protein 4 (NSP4) is known to function as an intracellular receptor at the endoplasmic reticulum (ER) critical to viral morphogenesis and is the first characterized viral enterotoxin. Exogenously added NSP4 induces diarrhea in rodent pups and stimulates secretory chloride currents across intestinal segments as measured in Ussing chambers. Circular dichroism studies further reveal that intact NSP4 and the enterotoxic peptide (NSP4114-135) that is located within the extended, C-terminal amphipathic helix preferentially interact with caveola-like model membranes. We now show colocalization of NSP4 and caveolin-1 in NSP4-transfected and rotavirus-infected mammalian cells in reticular structures surrounding the nucleus …


Financial Moral Panic! Sarbanes-Oxley, Financier Folk Devils, And Off-Balance Sheet Arrangement, Jose M. Gabilondo Jan 2006

Financial Moral Panic! Sarbanes-Oxley, Financier Folk Devils, And Off-Balance Sheet Arrangement, Jose M. Gabilondo

Faculty Publications

No abstract provided.


Note: Legal Excisions: The Rights Of Foreigners In Japan, Timothy Webster Jan 2006

Note: Legal Excisions: The Rights Of Foreigners In Japan, Timothy Webster

Faculty Publications

This article examines various moments in the constitutional rights of foreigners in Japan. Beginning with the drafting of the Japanese Constitution, it shows how Japanese members of the drafting committee did not passively accept whatever their American counterparts “foisted” on them, but quite deliberately sculpted and limited the reach of the Constitution through word choice and selective translation. It then examines several lawsuits, from the 1970s to the 2000s, where foreigners have asserted various rights in Japanese courts. In the absence of constitutional rights, foreigners must rely on Japanese statutory law, guided by international law, to buttress their claims to …


Bartnicki As Lochner: Some Thoughts On First Amendment Lochnerism, Howard M. Wasserman Jan 2006

Bartnicki As Lochner: Some Thoughts On First Amendment Lochnerism, Howard M. Wasserman

Faculty Publications

No abstract provided.


Toxic Torts, Autism, And Bad Science: Why The Courts May Be Our Best Defense Against Scientific Relativism, Joelle A. Moreno Jan 2006

Toxic Torts, Autism, And Bad Science: Why The Courts May Be Our Best Defense Against Scientific Relativism, Joelle A. Moreno

Faculty Publications

No abstract provided.


Winter Food Habits And Preferences Of Northern Bobwhites In East Texas, Donald R. Dietz, R. Montague Whiting Jr., Nancy E. Koerth Jan 2006

Winter Food Habits And Preferences Of Northern Bobwhites In East Texas, Donald R. Dietz, R. Montague Whiting Jr., Nancy E. Koerth

Faculty Publications

During late winter, 1994 and 1995, we investigated food habits and preferences of northern bobwhites (Colinus virginianus; hereafter, bobwhites) collected on forested lands in east Texas. Crops for bobwhites were collected from areas under 3 management regimes, namely intensively managed for bobwhites (QMA) (i.e., tree basal area reduced, annually burned, numerous multi-stage food plots, etc.), extensively managed for timber and wildlife (NBS) (i.e., burned every 3-5 years, scattered 2-stage food plots with corn feeders), and unmanaged for wildlife (i.e., burned every 5-7 years). With years pooled, partridge pea (Cassia fasciculata), Hercules club (Zanthoxylum clava-herculis), and pine (Pinus spp.) seeds, and …


Invasion Of Exotic Earthworms Into Ecosystems Inhabited By Native Earthworms, P. F. Hendrix, G. H. Baker, M. A. Callaham Jr., G. A. Damoff, C. Fragoso, G. Gonzalez, S. W. James, S. L. Lachnicht, T. Winsome, X. Zou Jan 2006

Invasion Of Exotic Earthworms Into Ecosystems Inhabited By Native Earthworms, P. F. Hendrix, G. H. Baker, M. A. Callaham Jr., G. A. Damoff, C. Fragoso, G. Gonzalez, S. W. James, S. L. Lachnicht, T. Winsome, X. Zou

Faculty Publications

The most conspicuous biological invasions in terrestrial ecosystems have been by exotic plants, insects and vertebrates. Invasions by exotic earthworms, although not as well studied, may be increasing with global commerce in agriculture, waste management and bioremediation. A number of cases has documented where invasive earthworms have caused significant changes in soil profiles, nutrient and organic matter dynamics, other soil organisms or plant communities. Most of these cases are in areas that have been disturbed (e.g., agricultural systems) or were previously devoid of earthworms (e.g., north of Pleistocene glacial margins). It is not clear that such effects are common in …


Creativity, Free Expression, And Professionalism: Value Conflicts In U.S. Community Radio, Michael Huntsberger Jan 2006

Creativity, Free Expression, And Professionalism: Value Conflicts In U.S. Community Radio, Michael Huntsberger

Faculty Publications

This study investigates how the values of free expression and professionalism provide the basis for interpersonal and organizational conflict in U.S. community radio stations, and shape divergent approaches to audience service. Using qualitative methods, the project examines the motivations, expressions, and behaviors of producers and managers to establish how their values contribute to cooperation and dissention within these organizations. The study illustrates the delicate balance that exists between content-centered and audience-centered objectives, concluding that these core values have a pervasive effect on community radio’s capacity to reach audiences and promote social change through the media.


Victims And Criminal Justice: What’S Next?, Michael M. O'Hear Jan 2006

Victims And Criminal Justice: What’S Next?, Michael M. O'Hear

Faculty Publications

No abstract provided.


Free Shoes For Primary And Secondary Schools: Playing By The Rules Of Title Ix, Patricia A. Cervenka Jan 2006

Free Shoes For Primary And Secondary Schools: Playing By The Rules Of Title Ix, Patricia A. Cervenka

Faculty Publications

Many credit Title IX with providing opportunities for girls to participate in athletics in greater numbers. The National Federation of State High School Associations show that the number of girls participating increased from 294,015 in 1971-1972 to 2,908,390 in 2004-2005, almost a tenfold increase. In the same time period the number of boys participating increased by 443,000. Girls participation has dramatically increased so the big picture is focused. Now attention is being drawn to some of the smaller aspects of Title IX compliance.

Shoe deals sidestep rules on equality in schools. Thus ran the headline in the Oregonian. The journalist …