Digital Commons Network^™

3d Printed High Density, Reversible, Chip-To-Chip Microfluidic Interconnects, Hua Gong, Adam T. Woolley, Gregory P. Nordin

Faculty Publications

Our latest developments in miniaturizing 3D printed microfluidics [Gong et al., Lab Chip, 2016, 16, 2450; Gong et al., Lab Chip, 2017, 17, 2899] offer the opportunity to fabricate highly integrated chips that measure only a few mm on a side. For such small chips, an interconnection method is needed to provide the necessary world-to-chip reagent and pneumatic connections. In this paper, we introduce simple integrated microgaskets (SIMs) and controlled-compression integrated microgaskets (CCIMs) to connect a small device chip to a larger interface chip that implements world-to-chip connections. SIMs or CCIMs are directly 3D printed as part of the device …

Acute Physiologic Stress And Subsequent Anxiety Among Family Members Of Icu Patients, Sarah J. Beesley, Ramona O. Hopkins, Julianne Holt-Lunstad, Emily L. Wilson, Jorie Butler, Kathryn G. Kuttler, James Orme, Samuel M. Brown, Eliotte L. Hirshberg

Faculty Publications

Objectives: The ICU is a complex and stressful environment and is associated with significant psychologic morbidity for patients and their families. We sought to determine whether salivary cortisol, a physiologic measure of acute stress, was associated with subsequent psychologic distress among family members of ICU patients.

Design: This is a prospective, observational study of family members of adult ICU patients.

Setting: Adult medical and surgical ICU in a tertiary care center.

Subjects: Family members of ICU patients. Interventions: Participants provided five salivary cortisol samples over 24 hours at the time of the patient ICU admission. The primary measure of cortisol …

Innovative Evangelism, Part 2: An Opportunity To Be Creative, S. Joseph Kidder, Kristy L. Hodson

Faculty Publications

"Most evangelistic ventures that have lasting results take time—months and maybe even years before you see the fruits of your investment. This is consistent with any type of relationship—they take time and effort to mature. “Relationships are like bank accounts: They don’t just happen.” All evangelism takes intentionality and should be done out of love for God and humanity and a desire to connect the two. The lack of an immediate result is not a sign of failure because evangelism is not about us—but about God. "

Trade-Offs And Synergies Of Ecosystem Services In The Taihu Lake Basin Of China, Xuning Qiao, Yangyang Gu, Changxin Zou, Lei Wang, Juhua Luo, Xianfeng Huang

Faculty Publications

Understanding the spatial interactions among multiple ecosystem services is crucial for ecosystem services management. Ecosystem services, including crop production, freshwater supply, aquatic production, net primary production, soil conservation, water conservation, flood regulation, forest recreation, were measured at 1-km grid scale covering the Taihu Lake Basin (TLB) of China. Our objective is to get a comprehensive understanding of the spatial distributions, trade-offs, synergies of multiple ecosystem services across the TLB. Our results found that: 1) majority of ecosystem services were clustered in space and had a similar spatial distribution pattern with the geographical resource endowment. Most of the landscape contributed a …

Does The Test Work? Evaluating A Web-Based Language Placement Test, Avizia Long, Sun-Young Shin, Kimberly Geeslin, Erik Willis

Faculty Publications

In response to the need for examples of test validation from which everyday language programs can benefit, this paper reports on a study that used Bachman’s (2005) assessment use argument (AUA) framework to examine evidence to support claims made about the intended interpretations and uses of scores based on a new web-based Spanish language placement test. The test, which consisted of 100 items distributed across five item types (sound discrimination, grammar, listening comprehension, reading comprehension, and vocabulary), was tested with 2,201 incoming first-year and transfer students at a large, Midwestern public university. Analyses of internal consistency and validity revealed the …

The Impact Of Brain Breaks Classroom-Based Physical Activities On Attitudes Toward Physical Activity In Polish School Children In Third To Fifth Grade, Agata Glapa, Joanna Grzesiak, Ida Laudanska-Krzeminska, Ming-Kai Chin, Christopher R. Edginton, Magdalena Mo Ching Mok, Michal Bronikowski

Faculty Publications

The purpose of this study was to examine the effectiveness of the Brain Breaks^® Physical Activity Solutions in changing attitudes toward physical activity of school children in a community in Poland. In 2015, a sample of 326 pupils aged 9–11 years old from 19 classes at three selected primary schools were randomly assigned to control and experimental groups within the study. During the classes, children in the experimental group performed physical activities two times per day in three to five minutes using Brain Breaks^® videos for four months, while the control group did not use the videos during …

Cummings, Merrill, And Borrelli’S Inquiry Into Small Screen Use By Academic Library Users: Timing Is Everything, Catharine Reese Bomhold

Faculty Publications

Objective – The authors undertook this study to understand the relatively new phenomenon of handheld computing and the use of small-screen devices among academic library users. They sought to determine if users would be inclined to search the online library catalogue on their devices and, by extension, if there would be a growing demand for small-screen compatible library services.

Design – Online and paper surveys were used with both closed and open questions. Respondents included students, faculty, and staff at Washington State University (WSU).

Setting – Washington State University Library, Pullman, Washington, United States of America. Subjects – The survey …

The Effect Of The Ehealth Intervention ‘Myplan 1.0’ On Physical Activity In Adults Who Visit General Practice: A Quasi-Experimental Trial, Laurent Degroote, Jolien Plaete, Ilse De Bourdeaudhuij, Maïté Verloigne, Vicky Van Stappen, An V. De Meester, Louise Poppe, Celien Van Der Mispel, Geert Crombez

Faculty Publications

Physical inactivity is one of the major risk factors for poor health in the world. Therefore, effective interventions that promote physical activity are needed. Hence, we developed an eHealth intervention for adults, i.e., ‘MyPlan 1.0’, which includes self-regulation techniques for behaviour change. This study examined the effect of ‘MyPlan 1.0’ on physical activity (PA) levels in general practice. 615 adults (≥18 years) were recruited in 19 Flemish general practices, for the intervention group (n = 328) or for the wait-list control group (n = 183). Participants in the intervention group received the web-based intervention ‘MyPlan 1.0’ and were prompted to …

Can Integrated Interventions Create The Conditions That Support Caregiving For Better Child Growth?, Purnima Menon, Edward A. Frongillo Jr.

Faculty Publications

No abstract provided.

Experimental Evidence Of A Pathogen Invasion Threshold, Tad A. Dallas, Martin Krkošek, John M. Drake

Faculty Publications

© 2018 The Authors. Host density thresholds to pathogen invasion separate regions of parameter space corresponding to endemic and diseasefree states. The host density threshold is a central concept in theoretical epidemiology and a common target of human and wildlife disease control programmes, but there is mixed evidence supporting the existence of thresholds, especially in wildlife populations or for pathogens with complex transmission modes (e.g. environmental transmission). Here, we demonstrate the existence of a host density threshold for an environmentally transmitted pathogen by combining an epidemiological model with a microcosm experiment. Experimental epidemics consisted of replicate populations of naive crustacean …

Helicobacter Pylori Moderates The Association Between 5-Mthf Concentration And Cognitive Function In Older Adults, Bruce L. Brown, Andrew N. Berrett, Shawn D. Gale, Lance D. Erickson, Dawson W. Hedges

Faculty Publications

Objective: To explore potential interactions between folate-cycle factors and Helicobacter pylori seropositivity in the prediction of cognitive function. Methods We used data obtained from the 1999–2000 continuous National Health and Nutrition Examination Survey produced by the United States’ Centers for Disease Control and Prevention. Using Ordinary Least Squares regression, we tested for associations between multiple folate-cycle factors, Helicobacter pylori seropositivity, and cognitive function assessed by the digit symbol coding subtest of the Wechsler Adult Intelligence Scale-III. We then tested for interactions between each of the folate-cycle factors and Helicobacter pylori in the prediction of cognitive function.

Results: Although Helicobacter pylori …

Experimental Evidence Of A Pathogen Invasion Threshold, Tad Dallas, Martin Krkošek, John M. Drake

Faculty Publications

Host density thresholds to pathogen invasion separate regions of parameter space corresponding to endemic and disease-free states. The host density threshold is a central concept in theoretical epidemiology and a common target of human and wildlife disease control programmes, but there is mixed evidence supporting the existence of thresholds, especially in wildlife populations or for pathogens with complex transmission modes (e.g. environmental transmission). Here, we demonstrate the existence of a host density threshold for an environmentally transmitted pathogen by combining an epidemiological model with a microcosm experiment. Experimental epidemics consisted of replicate populations of naive crustacean zooplankton (Daphnia dentifera …

Analysis Of Endocrine Response To Perceived Difference In Cross-Cultural Interactions, Carole Woolford-Hunt, Marlene Murray, Tevni Grajales Guerra, Kristina Beenken-Johnson

Faculty Publications

We live in a world where awareness of ethnic and cultural diversity is an ever increasing reality. Business and education turn to the social sciences to inform them about how to manage and optimize cross-cultural interactions. Although much research has been done on the impact of cross-cultural interactions on a wide range of variables, one less researched area is the endocrine response to cross-cultural interactions. In this study we set out to investigate the endocrine response to cross cultural interactions and the impact of these interactions on perceived differences. To do so we measured the pre and post levels of …

Preparing The Next Generation Of Instructional Designers: A Cross-Institution Faculty Collaboration, Patricia J. Slagter Van Tryon, Jason K. Mcdonald, Atsusi Hirumi

Faculty Publications

The ability of novice instructional designers to become skilled problem-solvers, who select and apply appropriate instructional design (ID) models in their work environments, are key competencies generally sought after in introductory ID courses. Yet, the proliferation of ID models, coupled with varied philosophies and practices about how ID is taught may pose challenges for ID educators seeking to prepare the next generation of leaders in the field. With little empirical research or documented best practices, ID educators are left to their own judgment about to how to navigate the practical challenges that can arise in the pursuit of their teaching …

Identifying Genome-Wide Immune Gene Variation Underlying Infectious Disease In Wildlife Populations - A Next Generation Sequencing Approach In The Gopher Tortoise, Jean P. Elbers, Mary B. Brown, Sabrina S. Taylor

Faculty Publications

Background: Infectious disease is the single greatest threat to taxa such as amphibians (chytrid fungus), bats (white nose syndrome), Tasmanian devils (devil facial tumor disease), and black-footed ferrets (canine distemper virus, plague). Although understanding the genetic basis to disease susceptibility is important for the long-term persistence of these groups, most research has been limited to major-histocompatibility and Toll-like receptor genes. To better understand the genetic basis of infectious disease susceptibility in a species of conservation concern, we sequenced all known/predicted immune response genes (i.e., the immunomes) in 16 Florida gopher tortoises, Gopherus polyphemus. All tortoises produced antibodies against Mycoplasma agassizii …

Peri-Elastodynamic Simulations Of Guided Ultrasonic Lamb Waves In Smart Structure With Surface Mounted Pzt, Subir Patra, Hossain Ahmed, Sourav Banerjee

Faculty Publications

Peridynamic based elastodynamic computation tool named Peri-elastodynamics is proposed herein to simulate the three-dimensional (3D) Lamb wave modes in materials for the first time. Peri-elastodynamics is a nonlocal meshless approach which is a scale-independent generalized technique to visualize the acoustic and ultrasonic waves in plate-like structure, micro-electro-mechanical systems (MEMS) and nanodevices for their respective characterization. In this article, the characteristics of the fundamental Lamb wave modes are simulated in a sample plate-like structure. Lamb wave modes are generated using a surface mounted piezoelectric (PZT) transducer which is actuated from the top surface. The proposed generalized Peri-elastodynamics method is not only …

Using Difference Scores To Inform Therapy Practice: Differences In Perceptions Of Attachment Behaviors Between Partners In A Clinical Sample, Joshua R. Novak, Jonathan G. Sandberg, Dean M. Busby

Faculty Publications

Using clinically relevant research methodology, this study focuses on differences (cross‐partner difference scores) in perceptions of attachment behaviors (emotional accessibility, responsiveness, and engagement) between partners in couples therapy. In general, findings suggest that higher levels of self‐enhancement attachment behaviors (participant perceives self as demonstrating more attachment behaviors than the partner's ratings of the participant) are associated with lower relationship satisfaction and greater relationship instability. The association between attachment behavior difference scores and measures of relationship health is mediated through partner perceived positive communication. These results suggest that differences in perceptions between partners’ level of attachment behaviors are an important clinical …

Reliability Of Pulse Waveform Separation Analysis Responses To An Orthostatic Challenge, Lee Stoner, Keeron Stone, Erik D. Hanson, James Faulkner, Simon Fryer, Daniel Credeur

Faculty Publications

Cardiovascular autonomic nervous system function can be assessed using an orthostatic challenge to induce arterial wave reflection. While arterial reflection is typically estimated using a central augmentation index, a superior estimation can be obtained using pulse wave separation analysis to estimate the aortic backward pressure wave (Pb). However, to be of value in a clinical or research setting, an assessment tool must be precise (reliable). Therefore, this study sought to determine the measurement precision of Pb responses to a modified tilt-table test. Twenty healthy adults (26.4 year (SD 5.2), 24.7kg/m² (SD 3.8), 55% female) were tested in a fasted …

Gratitude Predicts Hope And Happiness: A Two-Study Assessment Of Traits And States, Charlotte Vanoyen-Witvliet, Fallon J. Richie, Lindsey M. Root Luna, Daryl R. Van Tongeren

Faculty Publications

Gratitude is the appreciation of a gift received; happiness is the enjoyment of a present good; and hope is the desire for a valued future. Two studies investigated gratitude as a predictor of hope and happiness. In Study 1, hierarchical regressions (N = 181) revealed that trait gratitude exceeded other constructs (forgivingness, patience, self-control) in predicting trait hope and happiness. In Study 2, we experimentally tested the impact of a gratitude-related writing intervention on state hope and happiness. Participants (N = 153) first wrote about a current, meaningful, hoped-for outcome and completed state hope and happiness measures. Participants …

Analysis Of Emission Effects Related To Drivers’ Compliance Rates For Cooperative Vehicle-Infrastructure System At Signalized Intersections, Ruohua Liao, Xumei Chen, Lei Yu, Xiaofei Sun

Faculty Publications

Unknown remaining time of signal phase at a signalized intersection generally results in extra accelerations and decelerations that increase variations of operating conditions and thus emissions. A cooperative vehicle-infrastructure system can reduce unnecessary speed changes by establishing communications between vehicles and the signal infrastructure. However, the environmental benefits largely depend on drivers’ compliance behaviors. To quantify the effects of drivers’ compliance rates on emissions, this study applied VISSIM 5.20 (Planung Transport Verkehr AG, Karlsruhe, Germany) to develop a simulation model for a signalized intersection, in which light duty vehicles were equipped with a cooperative vehicle-infrastructure system. A vehicle-specific power (VSP)-based …

Independent Association Of Resting Energy Expenditure With Blood Pressure: Confirmation In Populations Of The African Diaspora, Chloe Creber, Richard S. Cooper, Jacob Plange-Rhule, Pascal Bovet, Estelle V. Lambert, Terrence E. Forrester, Dale Schoeller, Walter Riesen, Wolfgang Korte, Guichan Cao, Amy Luke, Lara R. Dugas

Faculty Publications

Background: Obesity is a major risk factor for hypertension, however, the physiologic mechanisms linking increased adiposity to elevations in blood pressure are not well described. An increase in resting energy expenditure (REE) is an obligatory consequence of obesity. Previous survey research has demonstrated that REE is an independent predictor of blood pressure, and eliminates the co-linear association of body mass index. This observation has received little attention and there have been no attempts to provide a causal explanation. Methods: At baseline in an international comparative study on obesity, 289 participants aged 25-44 were recruited from communities in the US, the …

Effects And Moderators Of Psychosocial Interventions On Quality Of Life, And Emotional And Social Function In Patients With Cancer: An Individual Patient Data Meta-Analysis Of 22 Rcts, J. Kalter, I. M. Verdonck-De Leeuw, M. G. Sweegers, N. K. Aaronson, P. B. Jacobsen, R. U. Newton, K. S. Courneya, J. F. Aitken, J. Armes, C. Arving, L. J. Boersma, A. M.J. Braamse, Y. Brandberg, S. K. Chambers, J. Dekker, K. Ell, R. J. Ferguson, M. F.M. Gielissen, B. Glimelius, M. M. Goedendorp, K. D. Graves, Sue P. Heiney, R. Horne, M. S. Hunter, B. Johansson, M. L. Kimman, H. Knoop

Faculty Publications

Objective: This individual patient data (IPD) meta-analysis aimed to evaluate the effects of psychosocial interventions (PSI) on quality of life (QoL), emotional function (EF), and social function (SF) in patients with cancer, and to study moderator effects of demographic, clinical, personal, and intervention-related characteristics. Methods: Relevant studies were identified via literature searches in 4 databases. We pooled IPD from 22 (n = 4217) of 61 eligible randomized controlled trials. Linear mixed-effect model analyses were used to study intervention effects on the post-intervention values of QoL, EF, and SF (z-scores), adjusting for baseline values, age, and cancer type. We studied …

Redesigning The Door To Doctor (D2d) Process In Emergency Department: The Key To A Successful Patient-Centered Story, Layal Hneiny, Maryah Damlaj

Faculty Publications

Lean management, when adopted in health care settings, will influence clinicians to find better ways for providing health care services to patients. In ED’s everyday processes, lean focuses on improving the ED process flow through facilitating communication among ED staff and eliminating any unnecessary steps (wastes) along the process. An observational cross-sectional study has been conducted at the Emergency Department (ED) of the American University of Beirut- Medical Center (AUBMC), to assess the extent upon which AUBMC-ED is lean. The time it takes the patient to be examined by an attending doctor, from the moment s/he hits the ED door, …

Nextgen Voices: Research Resolutions, Felicia Olmeta-Schult, Lauren Massa Segal, Sam Tyner, Twila Alexandra Moon, Ryan Dz Wei Chow, Prosanta Chakrabarty, Martin Pacesa, Anna Igorevna Podgornaia, Jennifer Chen, Bipin Singh, Bo Cao, Rishi Raj Singh Sidhu, Bryce W.Q. Tan, Prashant Sood, Stuart Parker, Matthew A. Scult, Desiree Van Haute, Nikos Konstantinides, Beat A. Schwendimann, Sudhakar Srivastava, Raffaele Fiorenza, Ken Dutton-Regester, Rachel Hale, Emre Ozan Polat, Edward Lau, Audrey L. Mayer, Easton R. White

Faculty Publications

No abstract provided.

New Wine, New Cloth, Hyveth Williams

Faculty Publications

No abstract provided.

The Application Of An Implementation Science Framework To Comprehensive School Physical Activity Programs: Be A Champion!, Justin B. Moore, Russell L. Carson, Collin A. Webster, Camelia Renee Singletary, Darla M. Castelli, Russell R. Pate, Michael W. Beets, Aaron Beighle

Faculty Publications

Comprehensive school physical activity programs (CSPAPs) have been endorsed as a promising strategy to increase youth physical activity (PA) in school settings. A CSPAP is a five-component approach, which includes opportunities before, during, and after school for PA. Extensive resources are available to public health practitioners and school officials regarding what should be implemented, but little guidance and few resources are available regarding how to effectively implement a CSPAP. Implementation science provides a number of conceptual frameworks that can guide implementation of a CSPAP, but few published studies have employed an implementation science framework to a CSPAP. Therefore, we developed …

Metavirome Sequencing Of The Termite Gut Reveals The Presence Of An Unexplored Bacteriophage Community, Chinmay V. Tikhe, Claudia Husseneder

Faculty Publications

The Formosan subterranean termite; Coptotermes formosanus is nutritionally dependent on the complex and diverse community of bacteria and protozoa in their gut. Although, there have been many studies to decipher the taxonomic and functional diversity of bacterial communities in the guts of termites, their bacteriophages remain unstudied. We sequenced the metavirome of the guts of Formosan subterranean termite workers to study the diversity of bacteriophages and other associated viruses. Results showed that the termites harbor a virome in their gut comprised of varied and previously unknown bacteriophages. Between 87-90% of the predicted dsDNA virus genes by Metavir showed similarity to …

Exosomes Serve As Novel Modes Of Tick-Borne Flavivirus Transmission From Arthropod To Human Cells And Facilitates Dissemination Of Viral Rna And Proteins To The Vertebrate Neuronal Cells, Wenshuo Zhou, Michael Woodson, Biswas Neupane, Fengwei Bai, Michael B. Sherman, Kyung H. Choi, Girish Neelakanta, Hameeda Sultana

Faculty Publications

Molecular determinants and mechanisms of arthropod-borne flavivirus transmission to the vertebrate host are poorly understood. In this study, we show for the first time that a cell line from medically important arthropods, such as ticks, secretes extracellular vesicles (EVs) including exosomes that mediate transmission of flavivirus RNA and proteins to the human cells. Our study shows that tick-borne Langat virus (LGTV), a model pathogen closely related to tick-borne encephalitis virus (TBEV), profusely uses arthropod exosomes for transmission of viral RNA and proteins to the human- skin keratinocytes and blood endothelial cells. Cryo-electron microscopy showed the presence of purified arthropod/neuronal exosomes …

In Vivo Inhibition Of Tryptophan Catabolism Reorganizes The Tuberculoma And Augments Immune-Mediated Control Of Mycobacterium Tuberculosis, Uma S. Gautam, Taylor W. Foreman, Allison N. Bucsan, Ashley V. Veatch, Xavier Alvarez, Toidi Adekambi, Nadia A. Golden, Kaylee M. Gentry, Lara A. Doyle-Meyers, Kasi E. Russell-Lodrigue, Peter J. Didier, James L. Blanchard, K. Gus Kousoulas, Andrew A. Lackner, Daniel Kalman, Jyothi Rengarajan, Shabaana A. Khader, Deepak Kaushal, Smriti Mehra

Faculty Publications

Mycobacterium tuberculosis continues to cause devastating levels of mortality due to tuberculosis (TB). The failure to control TB stems from an incomplete understanding of the highly specialized strategies that M. tuberculosis utilizes to modulate host immunity and thereby persist in host lungs. Here, we show that M. tuberculosis induced the expression of indoleamine 2,3-dioxygenase (IDO), an enzyme involved in tryptophan catabolism, in macrophages and in the lungs of animals (mice and macaque) with active disease. In a macaque model of inhalation TB, suppression of IDO activity reduced bacterial burden, pathology, and clinical signs of TB disease, leading to increased host …

Erratum: Correction To: Moderate Treadmill Exercise Protects Synaptic Plasticity Of The Dentate Gyrus And Related Signaling Cascade In A Rat Model Of Alzheimer's Disease (Molecular Neurobiology (2015) 52 3 (1067-1076)), An T. Dao, Munder A. Zagaar, Karim A. Alkadhi

Faculty Publications

The original version of this article unfortunately does not include the second affiliating institution of Dr. Munder A. Zagaar. "Department of Pharmacy Pracce and Clinical Health Sciences, Texas Southern University, Houston, TX 77004" should have been included on the paper.