Digital Commons Network^™

A Methodology For Nurse Staffing, Bruce M. Meglino

Faculty Publications

Increases in both staff salaries and in the number of personnel per patient have been prime factors in the rapid rise of hospital costs. This is particularly true in the nursing area, which is responsible for the greatest portion of these costs. Limited information has been available to aid hospital managers in the efficient utilization of the nursing staff. This article presents guidelines for determining patient load and a systematic procedure for allocating nursing personnel.

Adoption: A Plea For Realistic Constitutional Decisionmaking, Larry I. Palmer

Faculty Publications

No abstract provided.

Land Loss In Coastal Louisiana (U.S.A.), N. J. Craig, R. Eugene Turner, J. W. Day Jr.

Faculty Publications

This paper examines causes and consequences of wetland losses in coastal Louisiana. Land loss is a cumulative impact, the result of many impacts both natural and artificial. Natural losses are caused by subsidence, decay of abandoned river deltas, waves, and storms. Artificial losses result from flood-control practices, impoundments, and dredging and subsequent erosion of artificial channels. Wetland loss also results from spoil disposal upon wetlands and land reclamation projects.

Total land loss in Louisiana's coastal zone is at least 4,300 ha/year. Some wetlands are converted to spoil banks and other eco-systems so that wetland losses are probably two to three …

Nonenzymatically Glucosylated Albumin: In Vitro Preparation And Isolation From Normal Human Serum, James F. Day, Suzanne R. Thorpe, John W. Baynes

Faculty Publications

Incubation of human serum with D-[6-3H]glucose resulted in the gradual accumulation of radioactivity in acid-precipitable material. Upon chromatography on Sephadex G-200, radioactivity was found associated with each of the major molecular weight classes of serum protein. Purified human serum albumin was also glucosylated in vitro upon exposure to D-[6-3H]glucose in phosphate-buffered saline. The glucosylated and unmodified albumins were separated by ion exchange chromatography. The physiological significance of these observations in vitro was confirmed by the isolation and quantitation of glucosylated albumin from normal human serum. Glucosylated albumin represents approximately 6 to 15% of total serum albumin in normal adults. The …

An Experimental Analysis Of The Effects Of D‐Amphetamine And Cocaine On The Acquisition And Performance Of Response Chains In Monkeys, Donald M. Thompson, Joseph M. Moerschbaecher

Faculty Publications

In one component of a multiple schedule of food presentation, monkeys acquired a different four‐response chain each session by responding sequentially on three keys in the presence of four geometric forms (learning). In the other component, the four‐response chain was the same each session (performance). Both d‐amphetamine and cocaine, at the higher doses, disrupted the behavior in the learning component; the overall response rate decreased, the overall accuracy was impaired (i.e., percent errors increased), and there was less within‐session error reduction. The performance component was generally less sensitive than the learning component to the disruptive effects of both drugs on …

Effects Of Methamphetamine And Scopolamine On Variability Of Response Location, Joseph M. Moerschbaecher, Donald M. Thompson, John R. Thomas

Faculty Publications

Methamphetamine and scopolamine were studied in monkeys responding under a multiple fixed‐ratio fixed‐interval schedule of reinforcement. A response on any one of six levers could satisfy the schedule requirements. Variability of response location was evaluated in terms of switches, where a switch was defined as a response on one lever followed by a response on a different lever. Under baseline conditions the fixed‐ratio schedule generated a high rate of responding and a low level of variability, while the fixed‐interval schedule generated a low rate of responding and a high level of variability. Both methamphetamine (0.1 to 0.5 mg/kg) and scopolamine …

Effect Of Testosterone And Estradiol-17Β Alone And In Combination On Lh And Fsh Concentrations In Blood Serum And Pituitary Of Geldings And In Serum After Administration Of Gnrh, D. L. Thompson, B. W. Pickett, E. L. Squires, T. M. Nett

Faculty Publications

16 stallions were castrated and 30 days later assigned to 1 of 4 treatments: testosterone propionate (T, 175 μg/kg BW), estradiol-17β-3-benzoate (E, 44 μg/kg BW), the combination of both steroids (TE) or control (safflower oil). These dosages were administered every other day for 18 days (low dose) and then were doubled (high dose). Treatment at the high dose was continued for 27 days and the geldings were sacrificed. Treatment at the low dose resulted in concentrations of testosterone and estradiol in serum similar to those in intact stallions during the breeding season. Concentrations of LH and FSH in peripheral serum …

Variability In 24-Hour Urine Sodium Excretion In Children, Kiang Liu, Richard Cooper, Ivan Soltero, Jeremiah Stamler

Faculty Publications

How many 24-hour urine sodium measurements are adequate for characterizing a child's salt intake? Can overnight urine specimens accurately replace 24-hour collections for salt assessment? A sample of 73 6tb-8th grade children was taken from two parochial schools in Chicago to inrestigate systematically these questions. Seven consecutive 24-hour-urine specimens were collected from each child. The estimated ratio of intra- to inter-individual variances was 1.94 for 24-hour-urine sodium. Based on this value, eight 24-hour specimens are necessary to limit to 10% the diminution of the estimated correlation coefficient between 24- hour-urine sodium and blood pressure. Six measurements are required to reduce …

Can Overnight Urine Replace 24-Hour Urine Collection To Assess Salt Intake?, Kiang Liu, Alan R. Dyer, Richard S. Cooper, Rose Stamler, Jeremiah Stamler

Faculty Publications

Are overnight urine specimens adequate for characterizing the daily salt intake of individuals, i.e., can the overnight specimen replace the 24-bour specimen? Data from 142 male participants of an ongoing trial on the primary prevention of hypertension were used to examine this question with correlation analysis and quantile classification. Estimated correlation between the true mean 24-hour and the true mean overnight sodium excretion was 0.72. Furthermore, 67% of the individuals in the upper third of the distribution of true mean overnight urine sodium were also in the upper third of the distribution of true mean 24-hour sodium. Thus, these data …

Premature Probate: A Different Perspective On Guardianship For The Elderly, George J. Alexander

Faculty Publications

No abstract provided.

Government Publications: Human Rights, Jo Bell Whitlatch

Faculty Publications

No abstract provided.

State Medical Malpractice Screening Panels In Federal Diversity Actions, Vincent C. Alexander

Faculty Publications

During the early 1970's, a medical malpractice crisis was perceived in the United States. An increasing number of costly and time-consuming lawsuits alleging medical malpractice against doctors, hospitals, and other health care providers caused malpractice insurers to raise premiums substantially, which in turn threatened to curtail the availability of adequate health care at reasonable cost. State legislatures responded to the crisis with a variety of substantive and procedural measures intended to reduce the number of litigated claims and the size of jury awards. One of the principal steps taken in a majority of states was the creation of extrajudicial panels …

A Proposal For A Comprehensive Restructuring Of The Public Information System, Charles H. Koch Jr., Barry R. Rubin

Faculty Publications

No abstract provided.

Air Quality And Industrial Growth: The Location Of New Industiral Sources Of Pollution In Non-Attainment Areas, Ronald H. Rosenberg, Bruce A. Friedman

Faculty Publications

No abstract provided.

Government Publications: Government Information, Jo Bell Whitlatch

Faculty Publications

No abstract provided.

Fees For Information Services To Hospitals: A California Experience, Lawrence W. Onsager, George V. Summers Phd

Faculty Publications

The project was directed toward planning, developing, and implementing a subregional biomedical information network among the forty-three health care facilities (hospitals) of the four-county area served by Loma Linda University's health sciences library. The project coordinator contacted administrators and health care professionals in the forty-three institutions to present a plan for the network. The health care facilities were encouraged to support the continuation of the network through contract fees. The availability of specific information services was assured through contractual agreements. It was anticipated that the subregional network would be self-supporting after the twelve-month project period (December 1, 1976-November 30, 1977). …

[3H]‑Raffinose, A Novel Radioactive Label For Determining Organ Sites Of Catabolism Of Proteins In The Circulation, Jonathon Van Zile, Lee A. Henderson, John W. Baynes, Suzanne R. Thorpe

Faculty Publications

The primary tissue sites of catabolism of plasma proteins with long circulating half-lives are unknown. It has been difficult to identify these sites because plasma proteins are delivered to tissues at relatively slow rates but are rapidly degraded intracellularly within lysosomes. Therefore, a tracer attached to protein is lost from the site of uptake before an amount sufficient for quantitation can accumulate. We hypothesized that sucrose (Glupal-2 /3Fruf) would be a useful label to circumvent this difficulty because of the stability of sucrose in lysosomes; and thus, sucrose should remain in tissue long after the protein to which it was …

Bibliography Of Recommended Lists Of Books And Journals For Health Sciences Libraries, Lawrence W. Onsager

Faculty Publications

No abstract provided.

Locus Of Control, Knowledge Of Ethics, And Perceived Ethicality As Influenced By An Authority Figure, F. Matthew Mihelic, William G. Connolly

Faculty Publications

The present study investigated the relationship between a subject's locus of control, knowledge of psychological ethical research principles, and perceived ethicality of a psychological research proposal as influenced by an authority figure. Subjects were asked to judge the ethicality of a research proposal, which half were led to believe had been previously deemed unethical by an authority figure. No mention was made of the authority figure's viewpoint to the other subjects. The major finding was that the variability in ratings in ethicality of the research proposal tended to diminished from the no mention to the rejection manipulation in those of …

Review Of Economics As A Coordination Problem: The Contributions Of Friedrich A. Hayek By Gerald P. O’Driscoll, Jr., Jeffrey Rogers Hummel

Faculty Publications

No abstract provided.

Is The Free Market Ethical?, Fred Foldvary

Faculty Publications

A market free of coercion is on firm moral ground.

Studies Of Handicapped Students: Volume Ii: Teacher Identification Of Handicapped Pupils (Ages 6-11) Compared With Identification Using Other Indicators, Patricia Craig, David Kaskowitz, Mary Malgoire

Faculty Publications

Presented is a two-volume study of the characteristics of students identified as handicapped from educational, clinical, and psychological evaluations. The first volume describes an analysis (based on surveys collected by the National Center for Health Statistics) of the affects on identification of 14,185 6- to 17-year old students of family income, race, population size of place of residence, and geographic location. Among six primary findings reviewed are that all three types of teacher-identified handicaps (physical, mental, and speech) were significantly concentrated in the low income elementary school population, and that teachers identified both mental and speech handicaps at a significantly …

Eyewitness Identifications, Paul C. Giannelli

Faculty Publications

No abstract provided.

Enumeration, Isolation, And Characterization Of Beggiatoa From Freshwater Sediments, W. R. Strohl, J. M. Larkin

Faculty Publications

No abstract provided.

Timing Of Some Of The Molecular Events Required For Cell Fusion Induced By Herpes Simplex Virus Type 1, K. G. Kousoulas, S. Person, T. C. Holland

Faculty Publications

The timing of some of the molecular events that are required for cell fusion was investigated. Cell fusion was produced by a mutant of herpes simplex virus type 1 that causes extensive cell fusion during infection. The timing of molecular events required for fusion was established by the use of blocking agents. Phosphonoacetic acid blocks viral DNA synthesis; actinomycin D blocks RNA synthesis; cycloheximide blocks protein synthesis; 2-deoxyglucose blocks glycosylation of glycoproteins; high temperature, NH4Cl, and adamantanone block unknown steps required for cell fusion. For cells infected at a low multiplicity of infection, phosphonoacetic acid decreased the rate but not …

Operant Methodology In The Study Of Learning, D. M. Thompson, J. M. Moerschbaecher

Faculty Publications

A series of experiments is described in which operant methodology is used to study the effects of drugs on 'learning'. Emphasis is placed on the technique of repeated acquisition as a behavioral baseline for studying this type of transition state. In this technique, each subject is required to learn a new discrimination each session. Multiple-schedule procedures are also described in which acquisition is compared to a 'performance' task, where the discrimination is the same each session. The learning baseline is more sensitive to the disruptive effects of a variety of drugs (e.g., cocaine, d-amphetamine, haloperidol) than is the performance baseline. …

Acute And Chronic Effects Of Cocaine On Extinction‐Induced Aggression, Mitchell S. Moore, Donald M. Thompson

Faculty Publications

Pigeons worked individually in a chamber containing a response key and a mirror. Pecking on the key was controlled by a multiple schedule in which a brief period of continuous food reinforcement alternated with a 5‐minute period of extinction. Under baseline conditions, aggressive behavior (responding on the mirror) occurred at the onset of each extinction period. In Experiment I (acute drug administration), the aggressive behavior was decreased by doses of cocaine that had little or no effect on key pecking. Such food‐reinforced responding was disrupted, however, by higher doses of cocaine. An attempt to mimic the disruptive drug effects by …

Board Of Curators Of The University Of Missouri V. Horowitz: Academic Versus Judicial Expertise, R. Lawrence Dessem

Faculty Publications

In Board of Curators of the University of Missouri v. Horowitz' the United States Supreme Court rejected the argument that public university students are constitutionally entitled to a hearing prior to their dismissal from school for academic reasons. In ruling against a former medical student at the University of Missouri-Kansas City, the Court concluded that "the determination whether to dismiss a student for academic reasons requires an expert evaluation of cumulative information and is not readily adapted to the procedural tools of judicial or administrative decisionmaking. ' In this article that conclusion and the several opinions in Horowitz will be …

Proton Nuclear Magnetic Resonance Characterization Of Heme Disorder In Hemoproteins, G. N. La Mar, D. L. Budd, D. B. Viscio, K. M. Smith, K. C. Langry

Faculty Publications

A proton NMR method is described for determining the orientation of a porphyrin within the heme pocket of a hemoprotein. The pattern of the hyperfine-shifted heme methyl resonances in low-spin ferric model compounds is demonstrated to characteristically reflect the position of a localized low-symmetry perturbation on the π system. The specific assignments via deuteration of the two inconvertible sets of methyl resonances observed for deuteroporphyrin-reconstituted sperm whale metmyoglobin cyanide lead to the conclusion that the low-symmetry perturbations on the heme due to the apoprotein components by a 180°rotation about the α-γ meso axis. Hence the heme in the reconstituted myoglobin …

Trends In Mortality From Cerebrovascular Diseases In The United States, 1960 To 1975, Ivan Soltero, Kiang Liu, Richard Cooper, Jeremiah Stamler, Dan Garside

Faculty Publications

A long-term decline in death rates from cerebrovascular diseases in the United States accelerated in 1969, with a further increase in the rate of decline after 1972. This break in the pattern of the mortality curve for stroke was observed in all 4 major sex-color groups, and affected all age groups in which a significant number of stroke deaths occur. The decline for non-whites was relatively and absolutely greater than for the comparable white sex. If the 1960 rates had persisted in 1975, 87,600 more lives would have been lost to cerebrovascular diseases. Although there are no data documenting a …