Digital Commons Network^™

Agent-Based Coordinated Control Of Power Electronic Converters In A Microgrid, Maryam Nasri, Hebert L. Ginn Iii, Mehrdad Moallem

Faculty Publications

This paper presents the implementation of an agent-based architecture suitable for the coordination of power electronic converters in stand-alone microgrids. To this end, a publish-subscribe agent architecture was utilized as a distributed microgrid control platform. Over a distributed hash table (DHT) searching overlay, the publish-subscribe architecture was identified based on a numerical analysis as a scalable agent-based technology for the distributed real-time coordination of power converters in microgrids. The developed framework was set up to deploy power-sharing distributed optimization algorithms while keeping a deterministic time period of a few tens of milliseconds for a system with tens of converters and …

Associations Between Family-Based Stress And Dietary Inflammatory Potential Among Families With Preschool-Aged Children, Valerie Hruska, Nitin Shivappa Mbbs, Mph, Ph.D., James R. Hébert Scd, Alison M. Duncan, Jess Hines, David W. L. Ma

Faculty Publications

Chronic stress is known to influence dietary choices, and stressed families often report poorer diet quality; however, little is known about how family-based stress is linked with dietary patterns that promote inflammation. This study investigated associations between family-based stress and the inflammatory potential of the diet among preschool-aged children and their parents. Parents (n = 212 mothers, n = 146 fathers) and children (n = 130 girls, n = 123 boys; aged 18 months to 5 years) from 241 families participating in the Guelph Family Health Study were included in the analyses. Parents reported levels of parenting distress, depressive symptoms, …

Which Major Best Prepares You For Post-Grad Life?, Paul A. Djupe

Faculty Publications

No abstract provided.

Moving Morality Beyond The In-Group: Liberals And Conservatives Show Differences On Group-Framed Moral Foundations And These Differences Mediate The Relationships To Perceived Bias And Threat., Brandon D. Stewart Phd, David S. M. Morris

Faculty Publications

Moral foundations research suggests that liberals care about moral values related to individual rights such as harm and fairness, while conservatives care about those foundations in addition to caring more about group rights such as loyalty, authority, and purity. However, the question remains about how conservatives and liberals differ in relation to group-level moral principles. We used two versions of the moral foundations questionnaire with the target group being either abstract or specific ingroups or outgroups. Across three studies, we observed that liberals showed more endorsement of Individualizing foundations (Harm and Fairness foundations) with an outgroup target, while conservatives showed …

Impact Of Hurricane Michael (2018) On Local Vertical Total Electron Content, Joanna E.S. Williams, Robert C. Tournay, H. Rose Tseng, Daniel J. Emmons Ii, Omar A. Nava

Faculty Publications

An analysis of vertical total electron content (TEC) estimates from the MIT Madrigal database is performed for the regions surrounding the eye of Hurricane Michael (2018). Absolute and detrended TEC values show a noticeable increase during the tropical cyclone (TC) relative to fluctuations at the same locations prior to the storm. Direct comparisons of TEC perturbation magnitudes to the number of lightning flashes in latitude-longitude boxes surrounding the eye of Hurricane Michael for each 5 min period of 10 October 2018 showed no visible trends. A similar comparison of the vertical TEC fluctuations with respect to the rainfall rates showed …

Capture And Metabolomic Analysis Of The Human Endometrial Epithelial Organoid Secretome, Constantine A. Simintiras, Pramod Dhakal, Chaman Ranjit, Harriet C. Fitzgerald, Ahmed Z. Balboula, Thomas E. Spencer

Faculty Publications

Suboptimal uterine fluid (UF) composition can lead to pregnancy loss and likely contributes to offspring susceptibility to chronic adult-onset disorders. However, our understanding of the biochemical composition and mechanisms underpinning UF formation and regulation remain elusive, particularly in humans. To address this challenge, we developed a high-throughput method for intraorganoid fluid (IOF) isolation from human endometrial epithelial organoids. The IOF is biochemically distinct to the extraorganoid fluid (EOF) and cell culture medium as evidenced by the exclusive presence of 17 metabolites in IOF. Similarly, 69 metabolites were unique to EOF, showing asymmetrical apical and basolateral secretion by the in vitro …

Implications Of The Quantum Dna Model For Information Sciences, F. Matthew Mihelic

Faculty Publications

The DNA molecule can be modeled as a quantum logic processor, and this model has been supported by pilot research that experimentally demonstrated non-local communication between cells in separated cell cultures. This modeling and pilot research have important implications for information sciences, providing a potential architecture for quantum computing that operates at room temperature and is scalable to millions of qubits, and including the potential for an entanglement communication system based upon the quantum DNA architecture. Such a system could be used to provide non-local quantum key distribution that could not be blocked by any shielding or water depth, would …

Magnetic Vector Potential Manipulation Of Majorana Fermions In Dna Quantum Logic, F. Matthew Mihelic

Faculty Publications

In the quantum logic of the DNA molecule, electrons are held and conducted coherently as spinless Cooper pairs and are shielded from electromagnetic energy by a Faraday cage effect of the double lipid bilayer of the nuclear membrane. The magnetic vector potential generated by cellular depolarization can synchronize logical activity in portions of the DNA molecule by affecting spin directions of appropriately oriented spinless electrons via the Aharonov-Bohm effect, but is not blocked by that Faraday cage effect. Within the logically and thermodynamically reversible chiral enantiomeric symmetry of the deoxyribose moieties the decoherent transition of Cooper pair to Dirac pair …

Gastrointestinal Microenvironment And The Gut-Lung Axis In The Immune Responses Of Severe Covid-19, Yun Yang, Weishan Huang, Yubo Fan, Guo-Qiang Chen

Faculty Publications

The global pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an unprecedented threat to the human health. A close association of the digestive tract is implied by the high frequency of gastrointestinal syndromes among COVID-19 patients. A better understanding of the role of intestinal microenvironment in COVID-19 immunopathology will be helpful to improve the control of COVID-19 associated morbidity and mortality. This review summarizes the immune responses associated with the severity of COVID-19, the current evidence of SARS-CoV-2 intestinal tropism, and the potential involvement of gut microenvironment in COVID-19 severity. Additionally, we …

Is A Common Goal A False Hope In Convergence Research?: Opportunities And Challenges Of International Convergence Research To Address Arctic Change, Jessica G. Ernakovich, N. Eklund, Ruth K. Varner, N. Kirchner, J. Jeuring, Katharine Duderstadt, A. Granebeck, E. Golubeva, Asiaq Participants

Faculty Publications

The Arctic faces multiple pressures including climate change, shifting demographics, human health risks, social justice imbalances, governance issues, and expanding resource extraction. A convergence of academic disciplines—such as natural and social sciences, engineering and technology, health and medicine—and international perspectives is required to meaningfully contribute to solving the challenges of Arctic peoples and ecosystems. However, successfully carrying out convergent, international research and education remains a challenge. Here, lessons from the planning phase of a convergence research project concerned with the health of Arctic waters developed by the Arctic Science IntegrAtion Quest (ASIAQ) are discussed. We discuss our perspective on the …

Dietary Inflammatory Index Is Associated With Inflammation In Japanese Men, Ayaka Kotemori, Norie Sawada, Motoki Iwasaki, Taiki Yamaji, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert Scd, Junko Ishihara, Manami Inoue, Shoichiro Tsugane

Faculty Publications

Background: Dietary components are known to affect chronic low-grade inflammation status. The dietary inflammatory index (DII®) was developed to measure the potential impact of a diet on an individual's inflammatory status, and it has been validated mainly in Western countries.

Objective: This study aimed to examine the validity of the energy-adjusted DII (E-DIITM) using high-sensitivity C-reactive protein (hs-CRP) concentration in Japanese men and women.

Methods: In total, 6,474 volunteers from a cancer-screening program (3,825 men and 2,649 women) completed a food frequency questionnaire (FFQ) and their hs-CRP concentrations were evaluated. E-DII scores were calculated on the basis of 30 food …

Telepsychiatry Adoption Across Hospitals In The United States: A Cross-Sectional Study, Zhong Li, Sayward Harrison, Xiaoming Li, Peiyin Hung

Faculty Publications

Background: Access to psychiatric care is critical for patients discharged from hospital psychiatric units to ensure continuity of care. When face-to-face follow-up is unavailable or undesirable, telepsychiatry becomes a promising alternative. This study aimed to investigate hospital- and county-level characteristics associated with telepsychiatry adoption. Methods: Cross-sectional national data of 3475 acute care hospitals were derived from the 2017 American Hospital Association Annual Survey. Generalized linear regression models were used to identify characteristics associated with telepsychiatry adoption. Results: About one-sixth (548 [15.8%]) of hospitals reported having telepsychiatry with a wide variation across states. Rural noncore hospitals were less likely to adopt …

Telepsychiatry Adoption Across Hospitals In The United States: A Cross-Sectional Study, Zhong Li, Sayward Elizabeth Harrison Ph.D., Xiamoing Li Ph.D., Peiyin Hung

Faculty Publications

Background: Access to psychiatric care is critical for patients discharged from hospital psychiatric units to ensure continuity of care. When face-to-face follow-up is unavailable or undesirable, telepsychiatry becomes a promising alternative. This study aimed to investigate hospital- and county-level characteristics associated with telepsychiatry adoption.Methods: Cross-sectional national data of 3475 acute care hospitals were derived from the 2017 American Hospital Association Annual Survey. Generalized linear regression models were used to identify characteristics associated with telepsychiatry adoption.Results: About one-sixth (548 [15.8%]) of hospitals reported having telepsychiatry with a wide variation across states. Rural noncore hospitals were less likely to adopt telepsychiatry (8.3%) …

Dietary Inflammatory Index Is Related To Heart Failure Risk And Cardiac Function: A Case-Control Study In Heart Failure Patients, Jalal Moludi, Nitin Shivappa Mbbs, Mph, Ph.D., Soghra Alisgharzadeh, James R. Hébert Scd, Mohammad Alizadeh

Faculty Publications

Aims: Previous studies suggest that diet and inflammation are important risk factors for heart failure (HF); however, the associations remain unclear. The Dietary Inflammatory Index (DII®) was established to measure the inflammatory capacity of individuals' diet. This study aimed to explore the DII in HF subjects compared with controls. Methods and Results: We conducted a case–control (116 cases and 113 controls) study that recruited in the similar clinics. DII scores were calculated based on dietary intakes. N-Terminal pro-brain natriuretic peptide (NT-proBNP) levels and ejection fraction (EF) were assessed in both groups. In order to analyze DII scores with HF as …

Timing Of Term Elective Cesarean Section And Adverse Neonatal Outcomes: A Multi-Center Retrospective Cohort Study, Ayah Al Bizri, Nansi Boghossian, Anwar Nassar, Pascale Nakad, Dina Jaber, Rabih Chahine, Gaby Fallakha, Gjaotj Makhoul, Khalid Yunis

Faculty Publications

Background Rate of cesarean section (CS), including elective CS has globally increased. Studies have found that term elective CS before 39 weeks of gestation is associated with increased risk of adverse respiratory outcomes.

Objective To determine the rate of elective CS and examine the association between timing of elective term CS and adverse neonatal outcomes in a large population of Lebanese women.

Methods A Multi-Center Study was conducted using data from the National Collaborative Perinatal Neonatal Network database. Simple and multivariable logistic regression models were used to examine the association between timing of term elective CS and adverse neonatal outcomes. …

Maternal Pragmatic Language Difficulties In The Fmr1 Premutation And The Broad Autism Phenotype: Associations With Individual And Family Outcomes, Jessica Klusek, Angela John Thurman, Leonard Abbeduto

Faculty Publications

Broader phenotypes associated with genetic liability, including mild difficulties with pragmatic language skills, have been documented in mothers of children with autism spectrum disorder (ASD) and mothers of children with fragile X syndrome (FXS). This study investigated the relationship between pragmatic difficulties and indicators of maternal well-being and family functioning. Pragmatic difficulty was associated with loneliness in mothers of children with ASD or FXS, and with depression, decreased life satisfaction, and poorer family relationship quality but only in mothers of children with FXS. Results suggest that subtle maternal pragmatic language difficulties are a risk factor that that may contribute to …

Book Review: Social Media And Democracy: The State Of The Field And Prospects For Reform, Cynthia W. Bassett

Faculty Publications

Social Media and Democracy illuminates the empirical social science research done to date to tease apart the effects social media has had on representative democracies. It is a collection of essays by academic social scientists researching the intersection of social media and democracy from a variety of angles.

Calibration Of The Underground Muon Detector Of The Pierre Auger Observatory, A. Aab, P. Abreu, M. Aglietta, J. M. Albury, I. Allekotte, A. Almela, J. Alvarez-Muñiz, R. Alves Batista, G. A. Anastasi, L. Anchordoqui, B. Andrada, S. Andringa, C. Aramo, P. R. Araújo Ferreira, J. C. Arteaga Velázquez, H. Asorey, P. Assis, G. Avila, A. M. Badescu, A. Bakalova, A. Balaceanu, F. Barbato, R. J. Barreira Luz, K. H. Becker, J. A. Bellido, C. Berat, M. E. Bertaina, X. Bertou, P. L. Biermann, T. Bister, J. Biteau, J. Blazek, C. Bleve

Faculty Publications

To obtain direct measurements of the muon content of extensive air showers with energy above 101 eV, the Pierre Auger Observatory is currently being equipped with an underground muon detector (UMD), consisting of 219 10 m2-modules, each segmented into 64 scintillators coupled to silicon photomultipliers (SiPMs). Direct access to the shower muon content allows for the study of both of the composition of primary cosmic rays and of high-energy hadronic interactions in the forward direction. As the muon density can vary between tens of muons per m close to the intersection of the shower axis with the ground to much …

Mechanical Quantum Sensing In The Search For Dark Matter, D. Carney, G. Krnjaic, D. C. Moore, C. A. Regal, G. Afek, S. Bhave, B. Brubaker, T. Corbitt, J. Cripe, N. Crisosto, A. Geraci, S. Ghosh, J. G.E. Harris, A. Hook, E. W. Kolb, J. Kunjummen, R. F. Lang, T. Li, T. Lin, Z. Liu, J. Lykken, L. Magrini, J. Manley, N. Matsumoto, A. Monte, F. Monteiro, T. Purdy, C. J. Riedel, R. Singh, S. Singh, K. Sinha, J. M. Taylor, J. Qin, D. J. Wilson, Y. Zhao

Faculty Publications

Numerous astrophysical and cosmological observations are best explained by the existence of dark matter, a mass density which interacts only very weakly with visible, baryonic matter. Searching for the extremely weak signals produced by this dark matter strongly motivate the development of new, ultra-sensitive detector technologies. Paradigmatic advances in the control and readout of massive mechanical systems, in both the classical and quantum regimes, have enabled unprecedented levels of sensitivity. In this white paper, we outline recent ideas in the potential use of a range of solid-state mechanical sensing technologies to aid in the search for dark matter in a …

Su(3)-Guided Realistic Nucleon-Nucleon Interactions For Large-Scale Calculations, G. H. Sargsyan, K. D. Launey, R. B. Baker, T. Dytrych, J. P. Draayer

Faculty Publications

We examine nucleon-nucleon realistic interactions, based on their SU(3) decomposition to SU(3)-symmetric components. We find that many of these interaction components are negligible, which, in turn, allows us to identify a subset of physically relevant components that are sufficient to describe the structure of low-lying states in C12 and related observables, such as excitation energies, electric quadrupole transitions, and rms radii. We find that paring down the interaction by half or more yields results that practically coincide with the corresponding ab initio calculations with the full interaction. In addition, we show that while various realistic interactions differ in their SU(3) …

Stakeholder’S Risk Perceptions Ofwild Pigs: Is There A Gender Difference?, Maria Bampasidou, Michael D. Kaller, Shaun M. Tanger

Faculty Publications

Substantial literature indicates that genders differ in terms of risk perception and values regarding wildlife management. Lack of equal stakeholder representation is also documented, which can also impact the effectiveness of human-wildlife conflict resolution interventions and education and outreach efforts. This paper investigates gender differences in perceptions about risks and potential adverse impacts on production, health, environment, safety, and population management posed by wild pigs. A survey was used to collect data from a random sample of adult residents (N = 1221) in Louisiana. We analyzed responses from 226 female and 832 male producers. We observed differences in how these …

Genes Related To Redox And Cell Curvature Facilitate Interactions Between Caulobacter Strains And Arabidopsis, Louis Berrios, Bert Ely

Faculty Publications

Bacteria play an integral role in shaping plant growth and development. However, the genetic factors that facilitate plant-bacteria interactions remain largely unknown. Here, we demonstrated the importance of two bacterial genetic factors that facilitate the interactions between plant-growth-promoting (PGP) bacteria in the genus Caulobacter and the host plant Arabidopsis. Using homologous recombination, we disrupted the cytochrome ubiquinol oxidase (cyo) operon in both C. vibrioides CB13 and C. segnis TK0059 by knocking out the expression of cyoB (critical subunit of the cyo operon) and showed that the mutant strains were unable to enhance the growth of Arabidopsis. In addition, disruption of …

What Is Refractory Organic Matter In The Ocean?, Federico Baltar, Xosé A. Alvarez-Salgado, Javier Arístegui, Ronald Benner, Dennis A. Hansell, Gerhard J. Herndl, Christian Lønborg

Faculty Publications

About 20% of the organic carbon produced in the sunlit surface ocean is transported into the ocean’s interior as dissolved, suspended and sinking particles to be mineralized and sequestered as dissolved inorganic carbon (DIC), sedimentary particulate organic carbon (POC) or “refractory” dissolved organic carbon (rDOC). Recently, the physical and biological mechanisms associated with the particle pumps have been revisited, suggesting that accepted fluxes might be severely underestimated (Boyd et al., 2019; Buesseler et al., 2020). Perhaps even more poorly understood are the mechanisms driving rDOC production and its potential accumulation in the ocean. On the basis of …

Activating Mutations In Braf Disrupt The Hypothalamo-Pituitary Axis Leading To Hypopituitarism In Mice And Humans, Angelica Gualtieri, Nikolina Kyprianou, Louise C. Gregory, Maria Lillina Vignola, James G. Nicholson, Rachael Tan, Shin-Ichi Inoue, Valeria Scagliotti, Pedro Casado, James Blackburn, Fernando Abollo-Jimenez, Eugenia Marinelli, Rachael E.J. Besser, Wolfgang Högler, I. Karen Temple, Justin H. Davies, Andrey Gagunashvili, Iain C.A.F. Robinson, Sally A. Camper, Shannon W. Davis, Pedro R. Cutillas, Evelien F. Gevers, Yoko Aoki, Mehul T. Dattani, Carles Gaston-Massuet

Faculty Publications

Germline mutations in BRAF and other components of the MAPK pathway are associated with the congenital syndromes collectively known as RASopathies. Here, we report the association of Septo-Optic Dysplasia (SOD) including hypopituitarism and Cardio-Facio-Cutaneous (CFC) syndrome in patients harbouring mutations in BRAF. Phosphoproteomic analyses demonstrate that these genetic variants are gain-of-function mutations leading to activation of the MAPK pathway. Activation of the MAPK pathway by conditional expression of the Braf^V600E/+ allele, or the knock-in Braf^Q241R/+ allele (corresponding to the most frequent human CFC-causing mutation, BRAF p.Q257R), leads to abnormal cell lineage determination and terminal differentiation of …

I Saw The Lovely Jesus, Merlin D. Burt

Faculty Publications

No abstract provided.

Tax Administration And Racial Justice: The Illegal Denial Of Tax Based Pandemic Relief To The Nation's Incarcerated, Leslie Book

Faculty Publications

No abstract provided.

Fishing For Food: Values And Benefits Associated With Coastal Infrastructure, Cassandra M. Nieman, Alexie N. Rudman, Margaret L. Chory, Grant D. Murray, Luke Fairbanks, Lisa M. Campbell

Faculty Publications

While there is substantial literature about the socio-cultural characteristics and values associated with recreational and commercial fisheries in the U.S., studies directed at those who ‘fish for food’—those who depend on consuming their catch to various degrees—are relatively sparse. Using qualitative data collected through 80 semi-structured interviews with fishers in the summer and fall of 2018 in Carteret County, North Carolina, this study aims to better understand the group of recreational fishers who consume their catch by describing social and cultural dimensions and values associated with fishing for food, examining the role of infrastructure in facilitating access to benefits associated …

Are Granulins Copper Sequestering Proteins?, Anukool A. Bhopatkar, Vijayaraghavan Rangachari

Faculty Publications

Granulins (GRN 1-7) are short (~6 kDa), cysteine-rich proteins that are generated upon the proteolytic processing of progranulin (PGRN). These peptides, along with their precursor, have been implicated in multiple pathophysiological roles, especially in neurodegenerative diseases. Previously we showed that GRN-3 and GRN-5 are fully disordered in the reduced form implicating redox sensitive attributes to the proteins. Redox-based modulations are often carried out by metalloproteins in mitigating oxidative stress and maintaining metal-homeostasis within cells. To probe whether GRNs play a role in metal sequestration, we tested the metal binding propensity of the reduced forms of GRNs −3 and − 5 …

Microwave-Assisted Lignin Liquefaction In Hydrazine And Ethylene Glycol: Reaction Pathways Via Response Surface Methodology, Divine B. Nde, Mohamad Barekati-Goudarzi, Pranjali D. Muley, Lavrent Khachatryan, Dorin Boldor

Faculty Publications

Microwave assisted liquefaction (MAL) of alkali lignin in ethylene glycol (EG) in the presence of hydrazine was carried out using response surface methodology. Dielectric properties of mixtures of lignin/EG at different hydrazine concentrations were determined to enhance the understanding of the MAL process. MAL parameters were hydrazine concentration (1–3%), temperature (100-180 °C), time (5-45 min) with the maximum microwave heating power limited to 750 W. Lignin/EG ratio was fixed at 1 g:10 ml. Dielectric properties were significantly influenced by hydrazine concentration and temperature. Major products from the liquefaction process (as % of peak areas) were grouped into guaiacol and derivatives …

Surface Freshwater Fluxes In The Arctic And Subarctic Seas During Contrasting Years Of High And Low Summer Sea Ice Extent, Sarah B. Hall, Bulusu Subrahmanyam, Ebenezer S. Nyadjro, Annette Samuelsen

Faculty Publications

Freshwater (FW) flux between the Arctic Ocean and adjacent waterways, predominantly driven by wind and oceanic currents, influences halocline stability and annual sea ice variability which further impacts global circulation and climate. The Arctic recently experienced anomalous years of high and low sea ice extent in the summers of 2013/2014 and 2012/2016, respectively. Here we investigate the interannual variability of oceanic surface FW flux in relation to spatial and temporal variability in sea ice concentration (SIC), sea surface salinity (SSS), and sea surface temperature (SST), focusing on years with summer sea–ice extremes. Our analysis between 2010–2018 illustrate high parameter variability, …