Digital Commons Network^™

Altered Gut Microbiome In A Mouse Model Of Gulf War Illness Causes Neuroinflammation And Intestinal Injury Via Leaky Gut And Tlr4 Activation, Firas Alhasson, Suvarthi Das, Ratanesh K. Seth, Diptadip Dattaroy, Varun Chandrashekaran, Caitlin N. Ryan, Luisa S. Chan, Traci Testerman, James Burch, Lorne J. Hofseth, Ronnie Horner, Mitzi Nagarkatti, Prakash Nagarkatti, Stephen M. Lasley, Saurabh Chatterjee

Faculty Publications

Many of the symptoms of Gulf War Illness (GWI) that include neurological abnormalities, neuroinflammation, chronic fatigue and gastrointestinal disturbances have been traced to Gulf War chemical exposure. Though the association and subsequent evidences are strong, the mechanisms that connect exposure to intestinal and neurological abnormalities remain unclear. Using an established rodent model of Gulf War Illness, we show that chemical exposure caused significant dysbiosis in the gut that included increased abundance of phylum Firmicutes and Tenericutes, and decreased abundance of Bacteroidetes. Several gram negative bacterial genera were enriched in the GWI-model that included Allobaculum sp. Altered microbiome caused significant decrease …

Much Ado About The Tpp's Effect On Pharmaceuticals, Emily M. Morris

Faculty Publications

The Trans-Pacific Partnership Agreement’s many provisions that were beneficial to the pharmaceutical industry have caused a good deal of controversy. Specifically, critics allege that the TPP’s provisions requiring that member states expand patentable subject matter, adjust pharmaceutical patent terms, and link regulatory marketing approval to a drug's patent status would have raised drug prices and hindered access to medicines, particularly in developing countries. Closer examination of these provisions as well as the various ways in which member states can modify or ameliorate the effects of these provisions suggests that their potential effect on drug prices and access to health care …

A Video-Based Screening System For Automated Risk Assessment Using Nuanced Facial Features, Steven J. Pentland, Nathan W. Twyman, Judee K. Burgoon, Jay F. Nunamaker, Christopher B.R. Diller

Faculty Publications

This study investigates the development of an automated interviewing system that uses facial behavior as an indicator of the risk of given illicit behavior. Traditional facial emotion indicators of risk in semistructured dialogue may have limitations in an automated approach. However, an initial analysis of mock crime interviews suggests that the face may exhibit some form of rigidity during highly structured interviews. An interviewing system design using facial rigidity analysis was implemented and experimentally evaluated, the results of which further reveal that the rigidity is fairly generalized across the face. Whereas existing theory traditionally focuses on leakage of facial expressions, …

Crafting Precedent, Richard C. Chen

Faculty Publications

(with the Hon. Paul J. Watford & Marco Basile)

How does the law of judicial precedent work in practice? That is the question at the heart of The Law of Judicial Precedent, a recent treatise by Bryan Garner and twelve distinguished appellate judges. The treatise sets aside more theoretical and familiar questions about whether and why earlier decisions (especially wrong ones) should bind courts in new cases. Instead, it offers an exhaustive how-to guide for practicing lawyers and judges: how to identify relevant precedents, how to weigh them, and how to interpret them. This Review takes up the treatise on …

Tailored Judicial Selection, Dmitry Bam

Faculty Publications

American states have experimented with different methods of judicial selection for two centuries, creating uniquely American models of selection, like judicial elections, rarely used throughout the rest of the world. But despite the wide range of selection methods in existence throughout the nation, neither the American people nor legal scholars have given much thought to tailoring the selection method to particular levels of the judiciary. To the contrary, the most common approach to judicial selection in the United States is what I call a unilocular, “a judge is a judge,” approach. For most of our nation’s history, all judges within …

What Do We Really Know About How Habituation To Warnings Occurs Over Time? A Longitudinal Fmri Study Of Habituation And Polymorphic Warnings, Anthony Vance, Brock Kirwan, Daniel Bjornn, Jeff Jenkins, Bonnie Brinton Anderson

Faculty Publications

A major inhibitor of the effectiveness of security warnings is habituation: decreased response to a repeated warning. Although habituation develops over time, previous studies have examined habituation and possible solutions to its effects only within a single experimental session, providing an incomplete view of the problem. To address this gap, we conducted a longitudinal experiment that examines how habituation develops over the course of a five-day workweek and how polymorphic warnings decrease habituation. We measured habituation using two complementary methods simultaneously: functional magnetic resonance imaging (fMRI) and eye tracking.

Our results show a dramatic drop in attention throughout the workweek …

The Role Of Context In It Assimilation: A Multi-Method Study Of A Saas Platform In The Us Nonprofit Sector, Ryan T. Wright, Nicholas Roberts, David W. Wilson

Faculty Publications

Nonprofit organizations (NPOs) operate in environments characterized by growing competition for resources and greater stakeholder demands for accountability, which makes deploying and maintaining information systems a struggle. In this competitive, resource-constrained environment, enterprise Software-as-a-Service (SaaS) platforms offer NPOs a cost-effective way access reliable, low-maintenance information technology services. Thus, the extent to which NPOs assimilate SaaS is an important area of inquiry. Yet despite the wealth of research on organizational IT assimilation, we know little regarding whether, when, and how NPOs assimilate IT innovations. We further our understanding of NPO assimilation of SaaS by conducting a context-based study. To do so, …

Surgically Precise But Kinematically Abstract Patent Claims, Andrew Chin

Faculty Publications

No abstract provided.

Civilizing Criminal Settlements, Russell M. Gold, Carissa Byrne Hessick, F. Andrew Hessick

Faculty Publications

No abstract provided.

Dna Exonerations And The Elusive Promise Of Criminal Justice Reform, Carissa Byrne Hessick

Faculty Publications

Review of Wrongful Convictions and the DNA Revolution: Twenty-Five Years of Freeing the Innocent (Daniel S. Medwed ed., Cambridge University Press 2017).

Ideas About Nature In American Art And Visual Culture, Mark Graham

Faculty Publications

The stories we tell ourselves about nature deeply influence how we attempt to preserve, use, or restore nature as well as practices of art and art education that are concerned with ecological issues (Cronon 1996). Landscapes are culture before they are nature (Schama 1996). Yet, our ideas about wilderness, nature, landscape, and sustainability are fraught with paradox and debate. For example, Darwin’s fundamental assertions about the human relationship to nature continue to spark theological, political and educational controversies. Some environmentalists caution that our consumerist economy will destroy the planet and that we need to return to a less sophisticated technology …

The Perception And Production Of Two Vowel Mergers In Cowlitz County, Washington, Joseph A. Stanley

Faculty Publications

Recent literature has revealed ongoing variation in Pacific Northwest English. In particular, back vowels (cf. Ward 2003; Becker et al. 2013; McLarty & Kendall 2014) and pre-velar front vowels (cf. Wassink et al. 2009; Riebold 2015; 2015, and others) have received considerable attention. In this paper I present recent data from Cowlitz County, Washington that shed light other mergers involving these vowels.

As explained in the Atlas of North American English (Labov, Ash & Boberg 2006), some form of the conditioned merger of /e, ɛ, æ/ before intervocalic /r/, sometimes known as the Mary-merrymarry merger, is found in most varieties …

Teaching In The Age Of Humans Helping Students Think About Climate Change., Grinell Smith

Faculty Publications

To convey the magnitude and rapidity of current climate change and the severity of predictions for the next century, I present essential climate science information using four key sets of data and contextualize that information with personal anecdotes. I then consider the reasons for the large gap between the scientific consensus about anthropogenic climate change and public perceptions of that consensus. With several known challenges to climate change education in mind, I offer four recommendations for teachers that map relevant social psychology to pedagogy: (1) establish a learning community that works to disrupt in-group favoritism and reduce attribution bias; (2) …

A Potential Tool For Clinicians; Evaluating A Computer-Led Dietary Assessment Method In Overweight And Obese Women During Weight Loss, Adrianne Widaman, Nancy Keim, Dustin Burnett, Beverly Miller, Megan Witbracht, Keith Widaman, Kevin Laugero

Faculty Publications

Many Americans are attempting to lose weight with the help of healthcare professionals. Clinicians can improve weight loss results by using technology. Accurate dietary assessment is crucial to effective weight loss. The aim of this study was to validate a computer-led dietary assessment method in overweight/obese women. Known dietary intake was compared to Automated Self-Administered 24-h recall (ASA24) reported intake in women (n = 45), 19–50 years, with body mass index of 27–39.9 kg/m2. Participants received nutrition education and reduced body weight by 4%–10%. Participants completed one unannounced dietary recall and their responses were compared to actual intake. Accuracy of …

Enhancing Innovation In The Ugandan Agri-Food Sector: Progress, Constraints, And Possibilities, Travis Lybbert, Kritika Saxena, Julius Ecuru, Dick Kawooya, Sacha Wunsch-Vincent

Faculty Publications

No abstract provided.

Amphibians And Reptiles Of The State Of Chihuahua, Mexico, With Comparisons With Adjoining States, J. A. Lemos-Espinal, Geoffrey R. Smith, G. A. Woolrich-Pina, A. Cruz

Faculty Publications

No abstract provided.

Asor 2016 Annual Meeting, Paul J. Ray

Faculty Publications

No abstract provided.

Toxocara Seroprevalence And Associated Risk Factors In The United States, Bruce L. Brown, Andrew N. Berrett, Lance D. Erickson, Shawn D. Gale, Allison Stone, Dawson W. Hedges

Faculty Publications

Caused by the parasitic nematodes Toxocara canis and cati, toxocariasis in humans can result in covert toxocariasis, ocular toxocariasis, visceral larval migrans, and neurotoxocariasis. A common infection, toxocariasis exposure varies widely within and between countries, with a previous estimate of Toxocara seroprevalence using data from 1988 to 1994 in the United States of approximately 13%. Age, poverty, sex, educational attainment, ethnicity, and region have been associated with Toxocara seroprevalence. In this study, we sought to determine the seroprevalence of and factors associated with Toxocara seropositivity in the United States using data from the National Health and Nutrition Examination Survey from …

Corticosteroid-Laba Inhalers Increase Phonation Threshold Pressure (Ptp) And Flow (Ptf) In Rabbits, Christopher Dromey, Kristine Tanner, Heidi J. Robison, Maya Elena Stevens, Ray M. Merrill, Julie Barkmeier-Kraemer, Ben Christensen

Faculty Publications

Objectives: This study examined the effects of a combination corticosteroid plus long-acting beta2-adrenergic agonist inhaler (IC) on rabbit phonation. Methods: White New Zealand male rabbits were assigned randomly to experimental and control groups (n = 11 per group). The experimental group received twice-daily doses of Advair HFA™ (fluticasone propionate 45 mcg and salmeterol 21 mcg) via a veterinary facemask with 1-way valve and spacer; the control group received aerosolized saline. After 8 weeks, animals were euthanized, larynges excised, frozen, and subsequently thawed and mounted on a standard bench apparatus. Phonation was elicited during 15 successive trials, and phonation threshold pressure …

Spiritually Oriented Psychotherapy For Trauma And Meaning Making Among Ethnically Diverse Individuals In The United States, Kawika Allen, P. Scott Richards, T. Lea

Faculty Publications

Esmeralda, a 42-year-old Latina woman from Mexico, had moved to the United States with hopes of a bright new future. Despite not knowing much English, she had worked hard, found and married her husband, and had several beautiful children. She missed her family in Mexico, but loved living in the United States. At least, she had liked it up until the day her 5-year-old son was hit and killed by a truck only a few feet from where she stood. The accident had changed everything. In an instant, Esmeralda went from being a caring and involved mother to barely being …

Microcore: A Playable Case Study For Improving Adolescents’ Argumentative Writing In A Workplace Context, Derek L. Hansen, Jonathan Balzotti, Lauren Fine, Daniel Ebeling

Faculty Publications

A playable case study is an immersive, transmedia story controlled by a puppetmaster (i.e., teacher), but played by participants who advance the plot through their contributions and interactions with fictional characters. They are also explicitly educational, consisting of both the immersive, transmedia story, as well as in-game and out-of-game materials provided for educational scaffolding and reflection. We present the Microcore playable case study to illustrate the potential of this new type of experiential simulation that incorporates aspects of Alternate Reality Games (ARGs) to increase immersion. We present results from a pilot test of Microcore with an undergraduate course, identifying design …

Structural Covariance Of Sensory Networks, The Cerebellum, And Amygdala In Autism Spectrum Disorder, Garrett Cardon, Susan Hepburn, Donald C. Rojas

Faculty Publications

Sensory dysfunction is a core symptom of autism spectrum disorder (ASD), and abnormalities with sensory responsivity and processing can be extremely debilitating to ASD patients and their families. However, relatively little is known about the underlying neuroanatomical and neurophysiological factors that lead to sensory abnormalities in ASD. Investigation into these aspects of ASD could lead to significant advancements in our general knowledge about ASD, as well as provide targets for treatment and inform diagnostic procedures. Thus, the current study aimed to measure the covariation of volumes of brain structures (i.e., structural magnetic resonance imaging) that may be involved in abnormal …

The Effects Of Gamification On Corporate Compliance Training: A Field Experiment Of True Office Anti-Corruption Training Programs, Ryan J. Baxter, D. Kip Holderness, David A. Wood

Faculty Publications

Companies rely on internal controls to comply with the U.S. Foreign Corrupt Practices Act and the U.K. Bribery Act. One such control is anti-corruption employee training. Although corporate training is a key component of anti-fraud policies and procedures, it is often perceived as dull by employees. To motivate greater engagement, firms are experimenting with training that involves elements of digital games, known as gamification. We perform a field experiment with 158 employees of a large, multinational bank to examine the effectiveness of gamified anticorruption training. We find that employees strongly prefer gamified training to traditional, nongamified training and that gamified …

Making Ritual Strange: The Temple Cult As The Foundation For Tannaitic Discourse On Idolatry, Avram R. Shannon

Faculty Publications

This article examines the Tannaitic conception of the worship of avodah zarah. The term is commonly translated as “idolatry,”but the definition of what constitutes worship of avodah zarah, in m. Sanh. 7:6, is based on a more nuanced notion than simply worship of foreign gods. For the Sages of the Mishnah, worship of avodah zarah involved misuse of objects and rituals associated with the Temple cult, which constituted a betrayal of covenantal loyalty. This means that although the rabbinic laws against the worship of avodah zarah were based on the biblical prohibitions against worshiping other gods, the actual …

Formed In And Called From The Womb, Dana M. Pike

Faculty Publications

Jeremiah’s call narrative or vocation report includes a clear example of pre-birth divine election:

(1:4) “Now the word of the LORD came to me saying,

(1:5a) ‘Before I formed you in the womb [babbetẹ n] I knew you,

(5b) and before you were born [came forth from the womb/mēreḥem] I consecrated you;

(5c) I appointed you a prophet to the nations’” (Jer. 1:4–5; NRSV).

However, there is ambiguity about the meaning of the phrase “from the womb” and there are persistent questions about the relationship between Jeremiah 1:5a—“Before I formed you in the womb I knew you”—and 1:5b+c, “before you …

Lexicography In-Your-Face: The Active Semantics Of Pastaza Quichua Ideophones, Janis B. Nuckolls, Tod D. Swanson, Diana Shelton, Alexander Rice, Sarah Hatton

Faculty Publications

English:

We argue that a multimodal approach to defining a depictive class of words called ‘ideophones’ by linguists is essential for grasping their meanings. Our argument for this approach is based on the formal properties of Pastaza Quichua ideophones, which set them apart from the non-ideophonic lexicon, and on the cultural assumptions brought by speakers to their use. We analyze deficiencies in past attempts to define this language’s ideophones, which have used only audio data. We offer, instead, an audiovisual corpus which we call an ‘antidictionary’, because it defines words not with other words, but with clips featuring actual contexts …

The Latter-Day Saint Reimaging Of “The Breath Of Life” (Genesis 2:7), Dana M. Pike

Faculty Publications

The creation and flood accounts in Genesis in the Hebrew Bible (the Christian Old Testament) contain variations on a phrase commonly translated “the breath of life.” This phrase additionally occurs in some uniquely Latter-day Saint materials relating to creation. After overviewing and analyzing this phrase and its meaning in the Bible, this paper then examines the occurrences of the phrase “the breath of life” in important early Latter-day Saint texts.1 The purpose of this study is to illustrate and explain how and why many Latter-day Saints have come to often employ the phrase “the breath of life,” transforming its traditional …

The Genesis: A Symphonic Work And Analysis, Max Keller

Faculty Publications

The biblical account of creation found in the Book of Genesis is known to billions around the world through its proclamation by multiple religions and numerous denominations. As such it is embedded in many cultures, especially that of the Western civilization and art. This article contains all but two of the movements, three and six, of Max Keller’s analysis of his multi-movement symphonic work The Genesis. The work sought to be a musical expression of the creation narrative found in the Book of Genesis, with direct correlations to the original Hebrew text. As such, the analysis takes an in-depth look …

Capital Punishment Of Unintentional Felony Murder, Brenner M. Fissell, Guyora Binder, Robert Weisberg

Faculty Publications

Under the prevailing interpretation of the Eighth Amendment in the lower courts, a defendant who causes a death inadvertently in the course of a felony is eligible for capital punishment. This unfortunate interpretation rests on an unduly mechanical reading of the Supreme Court’s decisions in Enmund v. Florida and Tison v. Arizona, which require culpability for capital punishment of co-felons who do not kill. The lower courts have drawn the unwarranted inference that these cases permit execution of those who cause death without any culpability towards death. This Article shows that this mechanical reading of precedent is mistaken, because the …

Capabilities, Spillovers, And Intellectual Progress: Toward A Human Flourishing Theory For Intellectual Property, Brett Frischmann

Faculty Publications

Courts, commentators, and even casebooks mistakenly assume that intellectual property laws are fundamentally utilitarian and thus the relevant objective for intellectual property laws is maximizing social welfare. Economic theories of intellectual property dominate while rights-based theories and other alternatives struggle to remain relevant in the discourse. This essay accepts that intellectual property laws are consequentialist, but it mounts a challenge to the utilitarian theories that dominate. Following the path set by Amartya Sen in the area of development economics and borrowing heavily from the Sen’s analytical and normative framework — the Capabilities Approach, this essay begins to develop a human …