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Ubit Me!, Thomas Simmons Dec 2016

Ubit Me!, Thomas Simmons

Faculty Publications

No abstract provided.

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A Comparison Of Lysophosphatidylcholine And Crush Injury In A Rat Model Of Sciatic Nerve Regeneration, Ryan L. Wood, William G. Pitt, Scott C. Steffensen, Alonzo D. Cook Dec 2016

A Comparison Of Lysophosphatidylcholine And Crush Injury In A Rat Model Of Sciatic Nerve Regeneration, Ryan L. Wood, William G. Pitt, Scott C. Steffensen, Alonzo D. Cook

Faculty Publications

This study examined the effect of using lysophosphatidyl choline (LPC) in combination with a nerve crush injury on the healing rate of damaged left sciatic nerves in female rats. The rats were divided randomly into four groups: Control, LPC, Crush or Crush+ LPC. The Control group was the undamaged right sciatic nerve. The other groups were the damaged left sciatic nerve. The healing of the nerves was measured by monitoring gait, electrophysiological parameters: compound muscle action potential (CMAP) amplitudes and nerve conductance velocities (NCV); and morphological parameters: total fascicular area, total myelinated fiber counts, fiber densities, fiber diameters, and g-ratio. …

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Lin-Manuel Meets Moana, Daniel Pollack-Pelzner Dec 2016

Lin-Manuel Meets Moana, Daniel Pollack-Pelzner

Faculty Publications

In this article originally published in Public Books, Daniel Pollack-Pelzner wonders whether a Disney musical and a Lin-Manuel Miranda musical want the same thing.

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Peg3 Binds To H19-Icr As A Transcriptional Repressor, An Ye, Hongzhi He, Joomyeong Kim Dec 2016

Peg3 Binds To H19-Icr As A Transcriptional Repressor, An Ye, Hongzhi He, Joomyeong Kim

Faculty Publications

© 2016 Taylor & Francis Group, LLC. Paternally expressed gene 3 (Peg3) encodes a DNA-binding protein with 12 C2H2 zinc finger motifs. In the current study, we performed ChIP-seq using mouse embryonic fibroblast (MEF) cells. This experiment identified a set of 16 PEG3 genomic targets, the majority of which overlapped with the promoter regions of genes with oocyte expression. These potential downstream genes were upregulated in MEF cells lacking PEG3 protein, suggesting a potential repressor role for PEG3. Our study also identified the imprinting control region (ICR) of H19 as a genomic target. According to the results, PEG3 binds to …

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A Review Of The Tawny Crazy Ant, Nylanderia Fulva, An Emergent Ant Invader In The Southern United States: Is Biological Control A Feasible Management Option?, Zinan Wang, Lori Moshman, Emily C. Kraus, Blake E. Wilson, Namoona Acharya, Rodrigo Diaz Dec 2016

A Review Of The Tawny Crazy Ant, Nylanderia Fulva, An Emergent Ant Invader In The Southern United States: Is Biological Control A Feasible Management Option?, Zinan Wang, Lori Moshman, Emily C. Kraus, Blake E. Wilson, Namoona Acharya, Rodrigo Diaz

Faculty Publications

© 2016 by the authors; licensee MDPI, Basel, Switzerland. The tawny crazy ant, Nylanderia fulva (Mayr) (Hymenoptera: Formicidae), has invaded states of the U.S. including Texas, Louisiana, Mississippi, Alabama, Florida, and Georgia. Native to South America, N. fulva is considered a pest in the U.S. capable of annoying homeowners and farmers, as well as displacing native ant species. As it continues to expand its range, there is a growing need to develop novel management techniques to control the pest and prevent further spread. Current management efforts rely heavily on chemical control, but these methods have not been successful. A review …

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Crapemyrtle Bark Scale: A New Threat For Crapemyrtles, A Popular Landscape Plant In The U.S, Zinan Wang, Yan Chen, Mengmeng Gu, Erfan Vafaie, Michael Merchant, Rodrigo Diaz Dec 2016

Crapemyrtle Bark Scale: A New Threat For Crapemyrtles, A Popular Landscape Plant In The U.S, Zinan Wang, Yan Chen, Mengmeng Gu, Erfan Vafaie, Michael Merchant, Rodrigo Diaz

Faculty Publications

© 2016 by the authors; licensee MDPI, Basel, Switzerland. Crapemyrtle bark scale, Acanthococcus (=Eriococcus) lagerstroemiae (Kuwana) (Hemiptera: Eriococcidae), is a newly introduced insect pest on crapemyrtles, Lagerstroemia spp. (Myrtales: Lythraceae), one of the most popular flowering shrubs in the U.S. Since first detected in Texas in 2004, this pest has spread to twelve states causing losses to stakeholders. To develop a management plan, we reviewed current knowledge about the pest’s biology and ecology, and suggested research approaches including studying its thermal tolerance, host range, plant resistance and biological control. Parasitoids and predators have been reared from A. lagerstroemiae in the …

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Campaign 9 Of The K2 Mission: Observational Parameters, Scientific Drivers, And Community Involvement For A Simultaneous Space-And Ground-Based Microlensing Survey, Calen B. Henderson, Radosław Poleski, Matthew Penny, Rachel A. Street, David P. Bennett, David W. Hogg, B. Scott Gaudi, W. Zhu, T. Barclay, G. Barentsen, S. B. Howell, F. Mullally, A. Udalski, M. K. Szymański, J. Skowron, P. Mróz, S. Kozłowski, Wyrzykowski, P. Pietrukowicz, I. Soszyński, K. Ulaczyk, M. Pawlak, T. Sumi, F. Abe, Y. Asakura, R. K. Barry, A. Bhattacharya, I. A. Bond, M. Donachie, M. Freeman, A. Fukui, Y. Hirao, Y. Itow Dec 2016

Campaign 9 Of The K2 Mission: Observational Parameters, Scientific Drivers, And Community Involvement For A Simultaneous Space-And Ground-Based Microlensing Survey, Calen B. Henderson, Radosław Poleski, Matthew Penny, Rachel A. Street, David P. Bennett, David W. Hogg, B. Scott Gaudi, W. Zhu, T. Barclay, G. Barentsen, S. B. Howell, F. Mullally, A. Udalski, M. K. Szymański, J. Skowron, P. Mróz, S. Kozłowski, Wyrzykowski, P. Pietrukowicz, I. Soszyński, K. Ulaczyk, M. Pawlak, T. Sumi, F. Abe, Y. Asakura, R. K. Barry, A. Bhattacharya, I. A. Bond, M. Donachie, M. Freeman, A. Fukui, Y. Hirao, Y. Itow

Faculty Publications

K2ʼs Campaign 9 (K2C9) will conduct a ∼3.7 deg2 survey toward the Galactic bulge from 2016 April 22 through July 2 that will leverage the spatial separation between K2 and the Earth to facilitate measurement of the microlens parallax πE for ≳170 microlensing events. These will include several that are planetary in nature as well as many short-timescale microlensing events, which are potentially indicative of free-floating planets (FFPs). These satellite parallax measurements will in turn allow for the direct measurement of the masses of and distances to the lensing systems. In this article we provide an overview of the K2C9 …

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Evolutionary Innovation And Diversification Of Carotenoid-Based Pigmentation In Finches, Russell A. Ligon, Richard K. Simpson, Nicholas A. Mason, Geoffrey E. Hill, Kevin J. Mcgraw Dec 2016

Evolutionary Innovation And Diversification Of Carotenoid-Based Pigmentation In Finches, Russell A. Ligon, Richard K. Simpson, Nicholas A. Mason, Geoffrey E. Hill, Kevin J. Mcgraw

Faculty Publications

© 2016 The Author(s). Evolution © 2016 The Society for the Study of Evolution. The ornaments used by animals to mediate social interactions are diverse, and by reconstructing their evolutionary pathways we can gain new insights into the mechanisms underlying ornamental innovation and variability. Here, we examine variation in plumage carotenoids among the true finches (Aves: Fringillidae) using biochemical and comparative phylogenetic analyses to reconstruct the evolutionary history of carotenoid states and evaluate competing models of carotenoid evolution. Our comparative analyses reveal that the most likely ancestor of finches used dietary carotenoids as yellow plumage colorants, and that the ability …

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Sequence Capture And Next-Generation Sequencing Of Ultraconserved Elements In A Large-Genome Salamander, Catherine E. Newman, Christopher C. Austin Dec 2016

Sequence Capture And Next-Generation Sequencing Of Ultraconserved Elements In A Large-Genome Salamander, Catherine E. Newman, Christopher C. Austin

Faculty Publications

© 2016 John Wiley & Sons Ltd Amidst the rapid advancement in next-generation sequencing (NGS) technology over the last few years, salamanders have been left behind. Salamanders have enormous genomes—up to 40 times the size of the human genome—and this poses challenges to generating NGS data sets of quality and quantity similar to those of other vertebrates. However, optimization of laboratory protocols is time-consuming and often cost prohibitive, and continued omission of salamanders from novel phylogeographic research is detrimental to species facing decline. Here, we use a salamander endemic to the southeastern United States, Plethodon serratus, to test the utility …

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Habitat Use By Two Extremophile, Highly Endemic, And Critically Endangered Fish Species (Gambusia Eurystoma And Poecilia Sulphuraria; Poeciliidae), Zachary W. Culumber, Garrett W. Hopper, Nicholas Barts, Courtney N. Passow, Samuel Morgan, Anthony Brown, Lenin Arias-Rodriguez, Michael Tobler Dec 2016

Habitat Use By Two Extremophile, Highly Endemic, And Critically Endangered Fish Species (Gambusia Eurystoma And Poecilia Sulphuraria; Poeciliidae), Zachary W. Culumber, Garrett W. Hopper, Nicholas Barts, Courtney N. Passow, Samuel Morgan, Anthony Brown, Lenin Arias-Rodriguez, Michael Tobler

Faculty Publications

Effective conservation measures for endangered species require basic knowledge of habitat use and critical environmental variables influencing the species' occurrence. However, setting priorities may be difficult when multiple endangered species inhabit the same area and differ in habitat use. This study characterized the physical and chemical environment at 30 sites along a 2.5 km stretch of stream associated with the Baños del Azufre hydrogen sulphide spring complex, home to the only population of the widemouth gambusia (Gambusia eurystoma) in existence. Also present in the spring is Poecilia sulphuraria, a narrowly endemic and endangered species known from only a few populations. …

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Tlr8 Couples Socs-1 And Restrains Tlr7-Mediated Antiviral Immunity, Exacerbating West Nile Virus Infection In Mice, Amber M. Paul, Dhiraj Acharya, Linda Le, Penghua Wang, Dobrivoje S. Stokic, A. Arturo Leis, Lena Alexopoulou, Terrence Town, Richard A. Flavell, Erol Fikrig, Fengwei Bai Dec 2016

Tlr8 Couples Socs-1 And Restrains Tlr7-Mediated Antiviral Immunity, Exacerbating West Nile Virus Infection In Mice, Amber M. Paul, Dhiraj Acharya, Linda Le, Penghua Wang, Dobrivoje S. Stokic, A. Arturo Leis, Lena Alexopoulou, Terrence Town, Richard A. Flavell, Erol Fikrig, Fengwei Bai

Faculty Publications

West Nile virus (WNV) is a neurotropic ssRNA flavivirus that can cause encephalitis, meningitis, and death in humans and mice. Human TLR7 and TLR8 and mouse TLR7 recognize viral ssRNA motifs and induce antiviral immunity. However, the role of mouse TLR8 in antiviral immunity is poorly understood. In this article, we report that TLR8-deficient (Tlr8−/−) mice were resistant to WNV infection compared with wild-type controls. Efficient WNV clearance and moderate susceptibility to WNV-mediated neuronal death in Tlr8−/− mice were attributed to overexpression of Tlr7and IFN-stimulated gene-56 expression, whereas reduced expression of the proapoptotic gene coding Bcl2-associated X protein was observed. …

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Marine Microalgae: Climate, Energy, And Food Security From The Sea, Charles H. Greene, Mark E. Huntley, Ian Archibald, Léda N. Gerber, Deborah L. Sills, Joe Granados, Jefferson W. Tester, Colin M. Beal, Michael J. Walsh, Robert R. Bidigare, Susan L. Brown, William P. Cochlan, Zackary I. Johnson, Xin Gen Lei, Stephen C. Machesky, Donald Redalje, Ruth E. Richardson, Viswanath Kiron, Virginia Corless Dec 2016

Marine Microalgae: Climate, Energy, And Food Security From The Sea, Charles H. Greene, Mark E. Huntley, Ian Archibald, Léda N. Gerber, Deborah L. Sills, Joe Granados, Jefferson W. Tester, Colin M. Beal, Michael J. Walsh, Robert R. Bidigare, Susan L. Brown, William P. Cochlan, Zackary I. Johnson, Xin Gen Lei, Stephen C. Machesky, Donald Redalje, Ruth E. Richardson, Viswanath Kiron, Virginia Corless

Faculty Publications

Climate, energy, and food security are three of the greatest challenges society faces this century. Solutions for mitigating the effects of climate change often conflict with solutions for ensuring society’s future energy and food requirements. For example, BioEnergy with Carbon Capture and Storage (BECCS) has been proposed as an important method for achieving negative CO2 emissions later this century while simultaneously producing renewable energy on a global scale. However, BECCS has many negative environmental consequences for land, nutrient, and water use as well as biodiversity and food production. In contrast, large-scale industrial cultivation of marine microalgae can provide society with …

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Sacrifice At Khirbet Qumran And In The Dead Sea Scrolls: Implications For Understanding The Wilderness Tradition And Penitential Prayers, Kenneth Atkinson Dec 2016

Sacrifice At Khirbet Qumran And In The Dead Sea Scrolls: Implications For Understanding The Wilderness Tradition And Penitential Prayers, Kenneth Atkinson

Faculty Publications

No abstract provided.

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Giving Credit Where Credit Is Due: Reducing Inequality With A Progressive State Tax Credit, Eric Kades Dec 2016

Giving Credit Where Credit Is Due: Reducing Inequality With A Progressive State Tax Credit, Eric Kades

Faculty Publications

No abstract provided.

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From Warning To Wallpaper: Why The Brain Habituates To Security Warnings, Bonnie Anderson, Anthony Vance, C. Brock Kirwan, Jeffrey L. Jenkins, David Eargle Dec 2016

From Warning To Wallpaper: Why The Brain Habituates To Security Warnings, Bonnie Anderson, Anthony Vance, C. Brock Kirwan, Jeffrey L. Jenkins, David Eargle

Faculty Publications

Warning messages are fundamental to users' security interactions. Unfortunately, research has shown that they are largely ineffective. A key contributor to this failure is habituation: decreased response to a repeated warning. Previous research has inferred the occurrence of habituation to warnings or measured it indirectly, such as through the proxy of a related behavior. Therefore, there is a gap in our understanding of how habituation to security warnings develops in the brain. Without direct measures of habituation, we are limited in designing warnings that can mitigate its effects. In this study, we use neurophysiological measures to directly observe habituation as …

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Parental And Sexual Conflicts Over The Peg3 Imprinted Domain, Hongzhi He, Bambarendage P.U. Perera, An Ye, Joomyeong Kim Nov 2016

Parental And Sexual Conflicts Over The Peg3 Imprinted Domain, Hongzhi He, Bambarendage P.U. Perera, An Ye, Joomyeong Kim

Faculty Publications

© 2016 The Author(s). In the current study, the imprinting control region of the mouse Peg3 domain was deleted to test its functional impact on animal growth and survival. The paternal transmission of the deletion resulted in complete abolition of the transcription of two paternally expressed genes, Peg3 and Usp29, causing the reduced body weight of the pups. In contrast, the maternal transmission resulted in the unexpected transcriptional up-regulation of the remaining paternal allele of both Peg3 and Usp29, causing the increased body weight and survival rates. Thus, the imprinted maternal allele of the ICR may be a suppressor antagonistic …

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Using Caenorhabditis Elegans As A Model For Obesity Pharmacology Development, Jolene Zheng, Joseph R. Vasselli, Jason F. King, Michael L. King, Wenqian We, Zachary Fitzpatrick, William D. Johnson, John W. Finley, Roy J. Martin, Michael J. Keenan, Frederic M. Enright, Frank L. Greenway Nov 2016

Using Caenorhabditis Elegans As A Model For Obesity Pharmacology Development, Jolene Zheng, Joseph R. Vasselli, Jason F. King, Michael L. King, Wenqian We, Zachary Fitzpatrick, William D. Johnson, John W. Finley, Roy J. Martin, Michael J. Keenan, Frederic M. Enright, Frank L. Greenway

Faculty Publications

Copyright © 2015 Wolters Kluwer Health, Inc. The Caenorhabditis elegans model is a rapid and inexpensive method to address pharmacologic questions. We describe the use of C. elegans to explore 2 pharmacologic questions concerning candidate antiobesity drugs and illustrate its potential usefulness in pharmacologic research: (1) to determine a ratio of betahistine-olanzapine that blocks the olanzapine-induced intestinal fat deposition (IFD) as detected by Nile red staining and (2) to identify the mechanism of action of a pharmaceutical candidate AB-101 that reduces IFD. Olanzapine (53 mg/mL) increased the IFD (12.1 6 0.1%, P < 0.02), which was blocked by betahistine (763 mg/mL, 39.3 6 0.01%, P < 0.05) in wild-type C. elegans (N2). AB-101 (1.0%) reduced the IFD in N2 (P < 0.05), increased the pharyngeal pumping rate (P < 0.05), and reversed the elevated IFD induced by protease inhibitors atazanavir and ritonavir (P < 0.05). AB-101 did not affect IFD in a ACS null mutant strain acs-4(ok2872) III/hT2[bli-4(e937) let-?(q782) qIs48](I;III) suggesting an involvement of the lipid oxidation pathway and an upregulation of CPT-1. Our studies suggest that C. elegans may be used as a resource in pharmacologic research. This article is intended to stimulate a greater appreciation of its value in the development of new pharmaceutical interventions.

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Keeping The Promise Of Public Fiduciary Theory: A Reply To Leib And Galoob, Evan J. Criddle, Evan Fox-Decent Nov 2016

Keeping The Promise Of Public Fiduciary Theory: A Reply To Leib And Galoob, Evan J. Criddle, Evan Fox-Decent

Faculty Publications

No abstract provided.

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Photography-Based Taxonomy Is Inadequate, Unnecessary, And Potentially Harmful For Biological Sciences, Luis M.P. Ceríaco, Eliécer E. Gutiérrez, Alain Dubois, Cristian Simón Abdala, Abdulaziz S. Alqarni, Kraig Adler, Edson A. Adriano, Erna Aescht, Ishan Agarwal, Sabine Agatha, Donat Agosti, Antonio J.C. Aguiar, Jonas José Mendes Aguiar, Dirk Ahrens, Alexandre Aleixo, Maria Judite Alves, Fabio Raposo Do Amaral, Natalia Ananjeva, Marcelo C. Andrade, Marco Brandalise De Andrade, Franco Andreone, Pedro P.U. Aquino, Paula Beatriz Araujo, Henrard Arnaud, Jairo Arroyave, Wolfgang Arthofer, Tom J. Artois, Diego Astúa, Celso Azevedo, Justin C. Bagley, Diego Baldo, Helen Margaret Barber-James, Eva V. Bärmann Nov 2016

Photography-Based Taxonomy Is Inadequate, Unnecessary, And Potentially Harmful For Biological Sciences, Luis M.P. Ceríaco, Eliécer E. Gutiérrez, Alain Dubois, Cristian Simón Abdala, Abdulaziz S. Alqarni, Kraig Adler, Edson A. Adriano, Erna Aescht, Ishan Agarwal, Sabine Agatha, Donat Agosti, Antonio J.C. Aguiar, Jonas José Mendes Aguiar, Dirk Ahrens, Alexandre Aleixo, Maria Judite Alves, Fabio Raposo Do Amaral, Natalia Ananjeva, Marcelo C. Andrade, Marco Brandalise De Andrade, Franco Andreone, Pedro P.U. Aquino, Paula Beatriz Araujo, Henrard Arnaud, Jairo Arroyave, Wolfgang Arthofer, Tom J. Artois, Diego Astúa, Celso Azevedo, Justin C. Bagley, Diego Baldo, Helen Margaret Barber-James, Eva V. Bärmann

Faculty Publications

No abstract provided.

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The Constitution Of Agency Statutory Interpretation, Evan J. Criddle Nov 2016

The Constitution Of Agency Statutory Interpretation, Evan J. Criddle

Faculty Publications

No abstract provided.

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Fluctuating Temperatures Alter Environmental Pathogen Transmission In A Daphnia–Pathogen System, Tad Dallas, John M. Drake Nov 2016

Fluctuating Temperatures Alter Environmental Pathogen Transmission In A Daphnia–Pathogen System, Tad Dallas, John M. Drake

Faculty Publications

Environmental conditions are rarely constant, but instead vary spatially and temporally. This variation influences ecological interactions and epidemiological dynamics, yet most experimental studies examine interactions under constant conditions. We examined the effects of variability in temperature on the host–pathogen relationship between an aquatic zooplankton host (Daphnia laevis) and an environmentally transmitted fungal pathogen (Metschnikowia bicuspidata). We manipulated temperature variability by exposing all populations to mean temperatures of 20°C for the length of the experiments, but introducing periods of 1, 2, and 4 hr each day where the populations were exposed to 28°C followed by periods of …

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The Nature And Work Of The Holy Spirit In The Pentateuch, Richard M. Davidson Nov 2016

The Nature And Work Of The Holy Spirit In The Pentateuch, Richard M. Davidson

Faculty Publications

The Hebrew word ruakh refers to the divine Spirit some sixteen times in fifteen verses of the five books of Moses, and the Holy Spirit is also prefigured in several Pentateuchal passages dealing with typological aspects of the sanctuary services. Each of these passages contains profound insights into the nature and work of the Holy Spirit. It is the thesis of this study that all of the major aspects of the biblical doctrine of the Holy Spirit are set forth, at least in nascent form, in the foundational divine revelation which comprises the Torah. We will examine each of these …

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Faith In A World Of Unfaith: How To Share Christ With Unbelievers., Kleber D. Goncalves Nov 2016

Faith In A World Of Unfaith: How To Share Christ With Unbelievers., Kleber D. Goncalves

Faculty Publications

"Atheism comes out of a belief system that involves a decision. Christians have to make a similar kind of choice: to live by faith. To some extent, atheism requires “faith” that God does not exist. But how can we share our belief in the living God with nonbelievers in order to crack open a door instead of building a taller wall? How can we Seventh-day Adventists have a normal conversation about Jesus Christ in the twenty-first century without accidentally (or unconsciously) sounding aggressive, narrow-minded, or intolerant?"

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The Thr–His Connection On The Distal Heme Of Catalase-Related Hemoproteins: A Hallmark Of Reaction With Fatty Acid Hydroperoxides, Zahra Mashhadi, Marcia E. Newcomer, Alan R. Brash Nov 2016

The Thr–His Connection On The Distal Heme Of Catalase-Related Hemoproteins: A Hallmark Of Reaction With Fatty Acid Hydroperoxides, Zahra Mashhadi, Marcia E. Newcomer, Alan R. Brash

Faculty Publications

© 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim This review focuses on a group of heme peroxidases that retain the catalase fold in structure, yet show little or no reaction with hydrogen peroxide. Instead of having a role in oxidative defense, these enzymes are involved in secondary metabolite biosynthesis. The prototypical enzyme is catalase-related allene oxide synthase, an enzyme that converts a specific fatty acid hydroperoxide to the corresponding allene oxide (epoxide). Other catalase-related enzymes form allylic epoxides, aldehydes, or a bicyclobutane fatty acid. In all catalases (including these relatives), a His residue on the distal face of the …

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Soil Microbial Biomass And Function Are Altered By 12 Years Of Crop Rotation, Marshall D. Mcdaniel, A. Stuart Grandy Nov 2016

Soil Microbial Biomass And Function Are Altered By 12 Years Of Crop Rotation, Marshall D. Mcdaniel, A. Stuart Grandy

Faculty Publications

Declines in plant diversity will likely reduce soil microbial biomass, alter microbial functions, and threaten the provisioning of soil ecosystem services. We examined whether increasing temporal plant biodiversity in agroecosystems (by rotating crops) can partially reverse these trends and enhance soil microbial biomass and function. We quantified seasonal patterns in soil microbial biomass, respiration rates, extracellular enzyme activity, and catabolic potential three times over one growing season in a 12-year crop rotation study at the W. K. Kellogg Biological Station LTER. Rotation treatments varied from one to five crops in a 3-year rotation cycle, but all soils were sampled under …

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Twitter Predicts Citation Rates Of Ecological Research, Brandon K. Peoples, Stephen R. Midway, Dana Sackett, Abigail Lynch, Patrick B. Cooney Nov 2016

Twitter Predicts Citation Rates Of Ecological Research, Brandon K. Peoples, Stephen R. Midway, Dana Sackett, Abigail Lynch, Patrick B. Cooney

Faculty Publications

The relationship between traditional metrics of research impact (e.g., number of citations) and alternative metrics (altmetrics) such as Twitter activity are of great interest, but remain imprecisely quantified. We used generalized linear mixed modeling to estimate the relative effects of Twitter activity, journal impact factor, and time since publication on Web of Science citation rates of 1,599 primary research articles from 20 ecology journals published from 2012-2014. We found a strong positive relationship between Twitter activity (i.e., the number of unique tweets about an article) and number of citations. Twitter activity was a more important predictor of citation rates than …

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Fluctuating Temperatures Alter Environmental Pathogen Transmission In A Daphnia–Pathogen System, Tad Dallas, John M. Drake Nov 2016

Fluctuating Temperatures Alter Environmental Pathogen Transmission In A Daphnia–Pathogen System, Tad Dallas, John M. Drake

Faculty Publications

© 2016 The Authors. Ecology and Evolution published by John Wiley & Sons Ltd. Environmental conditions are rarely constant, but instead vary spatially and temporally. This variation influences ecological interactions and epidemiological dynamics, yet most experimental studies examine interactions under constant conditions. We examined the effects of variability in temperature on the host–pathogen relationship between an aquatic zooplankton host (Daphnia laevis) and an environmentally transmitted fungal pathogen (Metschnikowia bicuspidata). We manipulated temperature variability by exposing all populations to mean temperatures of 20°C for the length of the experiments, but introducing periods of 1, 2, and 4 hr each day where …

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Peg3 Interacts With Kap1 Through Krab-A, Hongzhi He, An Ye, Hana Kim, Joomyeong Kim Nov 2016

Peg3 Interacts With Kap1 Through Krab-A, Hongzhi He, An Ye, Hana Kim, Joomyeong Kim

Faculty Publications

© 2016 He et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Peg3 (Paternally Expressed Gene 3) is an imprinted gene that encodes a zinc finger DNAbinding protein. Peg3 itself is localized in the middle of a KRAB-A (Kruppel-Associated Box) zinc finger gene cluster. The amino acid sequence encoded by its exon 7 also shows sequence similarity to that of KRAB-A, suggesting Peg3 as a KRAB-containing zinc finger gene. As predicted, the PEG3 …

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Pancreatic Β-Cell Production Of Cxcr3 Ligands Precedes Diabetes Onset, Susan J. Burke, Michael D. Karlstad, Adrianna E. Eder, Kellie M. Regal, Danhong Lu, David H. Burk, J. Jason Collier Nov 2016

Pancreatic Β-Cell Production Of Cxcr3 Ligands Precedes Diabetes Onset, Susan J. Burke, Michael D. Karlstad, Adrianna E. Eder, Kellie M. Regal, Danhong Lu, David H. Burk, J. Jason Collier

Faculty Publications

© 2016 International Union of Biochemistry and Molecular Biology Type 1 diabetes mellitus (T1DM) results from immune cell-mediated reductions in function and mass of the insulin-producing β-cells within the pancreatic islets. While the initial trigger(s) that initiates the autoimmune process is unknown, there is a leukocytic infiltration that precedes islet β-cell death and dysfunction. Herein, we demonstrate that genes encoding the chemokines CXCL9, 10, and 11 are primary response genes in pancreatic β-cells and are also elevated as part of the inflammatory response in mouse, rat, and human islets. We further established that STAT1 participates in the transcriptional control of …

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Membership Trends In The American Ornithologists' Union And The Evolving Role Of Professional Ornithological Societies, Nicholas A. Mason, Michael W. Butler, Jennifer C. Owen Nov 2016

Membership Trends In The American Ornithologists' Union And The Evolving Role Of Professional Ornithological Societies, Nicholas A. Mason, Michael W. Butler, Jennifer C. Owen

Faculty Publications

No abstract provided.

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