Digital Commons Network^™

Gulf Of Mexico Hypoxia: Past, Present, And Future, Nancy N. Rabalais, R. Eugene Turner

Faculty Publications

One of the largest human-caused areas of bottom-water oxygen deficiency in the coastal ocean is on the northern Gulf of Mexico continental shelf adjacent to the Mississippi River, which discharges nitrogen and phosphorus loads into its surface waters. The beginnings of seasonal hypoxia (≤2 mg l−1 dissolved oxygen) in this area was in the 1950s with an acceleration in the worsening of severity during the 1970s. Currently, the bottom area of hypoxic areas can approach 23,000 km2, and the volume, 140 km3. Ecosystems, people, and economies are now at risk within the Mississippi River watershed and in the northern Gulf …

Bta-Mir-24-3p Controls The Myogenic Differentiation And Proliferation Of Fetal, Bovine, Skeletal Muscle-Derived Progenitor Cells By Targeting Acvr1b, Xin Hu, Yishen Xing, Ling Ren, Yahui Wang, Qian Li, Xing Fu, Qiyuan Yang, Lingyang Xu, Luc Willems, Junya Li, Lupei Zhang

Faculty Publications

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. MicroRNAs modulate a variety of cellular events, including skeletal muscle development, but the molecular basis of their functions in fetal bovine skeletal muscle development is poorly understood. In this study, we report that bta-miR-24-3p promotes the myogenic differentiation of fetal bovine PDGFRα- progenitor cells. The expression of bta-miR-24-3p increased during myogenic differentiation. Overexpression of bta-miR-24-3p significantly promoted myogenic differentiation, but inhibited proliferation. A dual-luciferase assay identified ACVR1B as a direct target of bta-miR-24-3p. Similarly, knocking down ACVR1B by RNA interference also significantly inhibited proliferation and promoted the differentiation of bovine PDGFRα- …

Incubation Recess Behaviors Influence Nest Survival Of Wild Turkeys, Nicholas W. Bakner, Bret A. Collier, Landon R. Schofield

Faculty Publications

In ground nesting upland birds, reproductive activities contribute to elevated predation risk, so females presumably use multiple strategies to ensure nest success. Identification of drivers reducing predation risk has primarily focused on evaluating vegetative conditions at nest sites, but behavioral decisions manifested through movements during incubation may be additional drivers of nest survival. However, our understanding of how movements during incubation impact nest survival is limited for most ground nesting birds. Using GPS data collected from female Eastern Wild Turkeys (n = 206), we evaluated nest survival as it relates to movement behaviors during incubation, including recess frequency, distance traveled …

Detection Of Chalk In Single Kernels Of Long-Grain Milled Rice Using Imaging And Visible/Near-Infrared Instruments, Christopher K. Addison

Faculty Publications

Background and objectives To maintain the competitiveness of U.S. long-grain rice in U.S. and foreign markets, having translucent whole milled grain is critical. An objective technique to detect grain chalk, opaque areas in the grain, will provide breeders and industry with an effective tool for developing low-chalk varieties or agronomic practices that reduce chalk occurrence. Two instruments developed at the Center for Grain and Animal Health Research, U.S. Department of Agriculture-Agricultural Research Service (USDA-ARS), a single-kernel near-infrared (SKNIR) tube instrument and a silicon-based light-emitting diode (SiLED) high-speed sorter, were compared with two commercially available imaging instruments, WinSEEDLE and SeedCount used …

Integrating Geochronologic And Instrumental Approaches Across The Bengal Basin, Carol Wilson

Faculty Publications

Constraining time is of critical importance to evaluating the rates and relative contributions of processes driving landscape change in sedimentary basins. The geomorphic character of the field setting guides the application of geochronologic or instrumental tools to this problem, because the viability of methods can be highly influenced by geomorphic attributes. For example, sediment yield and the linked potential for organic preservation may govern the usefulness of radiocarbon dating. Similarly, the rate of sediment transport from source to sink may determine the maturity and/or light exposure of mineral grains arriving in the delta and thus the feasibility of luminescence dating. …

References To Movies In Judicial Opinions And Written Advocacy, Part 2, Douglas E. Abrams

Faculty Publications

In the Journal’s September- October issue, Part I of this article sampled recent federal and state judicial opinions that cite themes, scenes, or characters from movies listed on the American Film Institute (AFI) “100 Greatest American Films of All Time.” This Part II picks up where Part I left off. The discussion below samples recent judicial opinions that cite other well-known movies that have captivated American audiences without winning places on the “100 Greatest” list. Part II concludes by explaining why brief writers should feel comfortable following the judges’ lead by carefully using movie references to help make written substantive …

Testing Predictability Of Disease Outbreaks With A Simple Model Of Pathogen Biogeography, Tad A. Dallas, Colin J. Carlson, Timothée Poisot

Faculty Publications

© 2019 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited. Predicting disease emergence and outbreak events is a critical task for public health professionals and epidemiologists. Advances in global disease surveillance are increasingly generating datasets that are worth more than their component parts for prediction-oriented work. Here, we use a trait-free approach which leverages information on the global community of human infectious diseases to predict the biogeography of pathogens through time. Our approach takes pairwise dissimilarities between countries’ pathogen …

Avian Ecological Succession In The Amazon: A Long-Term Case Study Following Experimental Deforestation, Cameron L. Rutt, Vitek Jirinec

Faculty Publications

Approximately 20% of the Brazilian Amazon has now been deforested, and the Amazon is currently experiencing the highest rates of deforestation in a decade, leading to large-scale land-use changes. Roads have consistently been implicated as drivers of ongoing Amazon deforestation and may act as corridors to facilitate species invasions. Long-term data, however, are necessary to determine how ecological succession alters avian communities following deforestation and whether established roads lead to a constant influx of new species. We used data across nearly 40 years from a large-scale deforestation experiment in the central Amazon to examine the avian colonization process in a …

Innovative Accounting Interviewing: A Comparison Of Real And Virtual Accounting Interviewers, Matthew D. Pickard, Ryan Schuetzler, Joseph S. Valacich, David A. Wood

Faculty Publications

Recent technological advances have made it possible to create automated, virtual interviewers, called embodied conversational agents (ECAs). We study how an ECA compares to a human interviewer in three experiments. In experiment 1, we show that two theoretically motivated factors—making the ECA facially and vocally similar to the interviewee—result in the ECA performing similarly to or better than human interviewers for six antecedents of disclosure quality. In two additional experiments, we show that employees are on average between 21 and 32 percent more likely to disclose violating internal controls to an ECA than to a human interviewer, even if the …

Late Pleistocene Site Formation And Paleoclimate At Lapa Do Picareiro, Portugal, Michael M. Benedetti, Jonathan A. Haws, Nuno F. Bicho, Lukas Friedl, Brooks B. Ellwood

Faculty Publications

© 2019 Wiley Periodicals, Inc. The cave site of Lapa do Picareiro, Portugal contains a deep (~10 m) sedimentary sequence representing much of the Middle and Upper Paleolithic, with abundant animal bones, lithic/bone/shell artifacts, and charcoal/ash in hearths. A deposition model based on 49 radiocarbon ages demonstrates average sedimentation rates of 0.1–0.3 mm a −1 between 9 and 45 ka. Extrapolation suggests an age at the base of the excavation of 65–78 ka. The cave sediments are primarily limestone éboulis derived from roof spalling, and muddy fine sediment derived from weathered soil infiltrating through bedrock joints and crevices. Bone preservation …

Information Asymmetry And The Protection Of Ordinary Investors, Kevin S. Haeberle

Faculty Publications

To some, the reductions in information asymmetry provided by the main securities-specific disclosure, fraud, and insider-trading laws help ordinary investors in meaningful ways. To others, whatever their larger social value, such reductions do little, if anything for these investors. For decades, these two sides of this investor-protection divide have mostly talked past each other.

This Article builds on economic theory to reveal something striking: The reductions in information asymmetry provided by the core securities laws likely impose a long-overlooked cost on buy-and-hold ordinary investors. More specifically, I explain why there is much reason to believe that the reductions take away …

A Political Interpretation Of Vagueness Doctrine, Brenner M. Fissell, Guyora Binder

Faculty Publications

The “void-for-vagueness” doctrine requires the specific definition of criminal offenses. In this Article, though, we claim it does more: it largely restricts criminalization decisions to legislatures, which are unlikely to criminalize conduct they see as both harmless and widespread. Thus, rather than constitutionalizing the harm principle and thereby assuming a judicial obligation to define harm, the Supreme Court has used the vagueness doctrine to constrain majorities to make their own assessments of harmfulness. While American law has no explicit requirements that criminal liability be created by legislation or conditioned on harm, the vagueness doctrine achieves those ends indirectly

A Private Enforcement Remedy For Information Misuse, Peter Ormerod

Faculty Publications

Misuse of users’ personally identifiable information is persistent and pervasive. This Article addresses two questions: why is information misuse so common and so severe and how could domestic law change to make it less so? I use a simple model to illustrate that companies externalize information misuse costs onto users, which has two related but distinct effects: chronic underinvest- ment in information security and excessive retention of user data. I then seize on this observation to propose a specific legal vehicle at the heart of this Article—a private enforcement remedy. This private enforcement remedy has four essential features. First, the …

Repeated Vaginal Exposures To The Common Cosmetic And Household Preservative Methylisothiazolinone Induce Persistent, Mast Cell-Dependent Genital Pain In Nd4 Mice, Erica Arriaga-Gomez, Jacyln Kline, Elizabeth Emanuel, Nefeli Neamonitaki, Tenzin Yangdon, Hayley Zacheis, Dogukan Pasha, Jinyoung Lim, Susan Bush, Beebie Boo, Hanna Mengistu, Ruby Kinnamon, Robin Shields-Cutler, Wattenberg Wattenberg, Devavani Chatterjea

Faculty Publications

A history of allergies doubles the risk of vulvodynia-a chronic pain condition of unknown etiology often accompanied by increases in numbers of vulvar mast cells. We previously established the biological plausibility of this relationship in mouse models where repeated exposures to the allergens oxazolone or dinitrofluorobenzene on the labiar skin or inside the vaginal canal of ND4 Swiss Webster outbred mice led to persistent tactile sensitivity and local increases in mast cells. In these models, depletion of mast cells alleviated pain. While exposure to cleaning chemicals has been connected to elevated vulvodynia risk, no single agent has been linked to …

Oyster Reefs In Northern Gulf Of Mexico Estuaries Harbor Diverse Fish And Decapod Crustacean Assemblages: A Meta-Synthesis, Megan K. La Peyre, Danielle Aguilar Marshall, Lindsay S. Miller

Faculty Publications

Oyster reefs provide habitat for numerous fish and decapod crustacean species that mediate ecosystem functioning and support vibrant fisheries. Recent focus on the restoration of eastern oyster (Crassostrea virginica) reefs stems from this role as a critical ecosystem engineer. Within the shallow estuaries of the northern Gulf of Mexico (nGoM), the eastern oyster is the dominant reef building organism. This study synthesizes data on fish and decapod crustacean occupancy of oyster reefs across nGoM with the goal of providing management and restoration benchmarks, something that is currently lacking for the region. Relevant data from 23 studies were identified, representing data …

Genomic Selection In Rubber Tree Breeding: A Comparison Of Models And Methods For Managing G×E Interactions, Livia M. Souza, Felipe R. Francisco, Paulo S. Gonçalves, Erivaldo J. Scaloppi Junior, Vincent Le Guen, Roberto Fritsche-Neto, Anete P. Souza

Faculty Publications

Several genomic prediction models combining genotype × environment (G×E) interactions have recently been developed and used for genomic selection (GS) in plant breeding programs. G×E interactions reduce selection accuracy and limit genetic gains in plant breeding. Two data sets were used to compare the prediction abilities of multienvironment G×E genomic models and two kernel methods. Specifically, a linear kernel, or GB (genomic best linear unbiased predictor [GBLUP]), and a nonlinear kernel, or Gaussian kernel (GK), were used to compare the prediction accuracies (PAs) of four genomic prediction models: 1) a single-environment, main genotypic effect model (SM); 2) a multienvironment, main …

Core–Shell Nanospheres Behind The Blue Eyes Of The Bay Scallop Argopecten Irradians, Olivia K. Harris, Alexandra C.N. Kingston, Caitlin S. Wolfe, Soumitra Ghoshroy, Sönke Johnsen, Daniel Isaac Speiser

Faculty Publications

The bay scallop Argopecten irradians (Mollusca: Bivalvia) has dozens of iridescent blue eyes that focus light using mirror-based optics. Here, we test the hypothesis that these eyes appear blue because of photonic nanostructures that preferentially scatter short-wavelength light. Using transmission electron microscopy, we found that the epithelial cells covering the eyes of A. irradians have three distinct layers: an outer layer of microvilli, a middle layer of random close-packed nanospheres and an inner layer of pigment granules. The nanospheres are approximately 180 nm in diameter and consist of electron-dense cores approximately 140 nm in diameter surrounded by less electron-dense shells …

Gut Dna Virome Diversity And Its Association With Host Bacteria Regulate Inflammatory Phenotype And Neuronal Immunotoxicity In Experimental Gulf War Illness, Ratanesh K. Seth, Rabia Maqsood, Ayan Mondal, Dipro Bose, Diana Kimono, Larinda A. Holland, Patricia Janulewicz Lloyd, Nancy Klimas, Ronnie Horner, Kimberly Sullivan, Efrem S. Lim, Saurabh Chatterjee

Faculty Publications

Gulf War illness (GWI) is characterized by the persistence of inflammatory bowel disease, chronic fatigue, neuroinflammation, headache, cognitive impairment, and other medically unexplained conditions. Results using a murine model show that enteric viral populations especially bacteriophages were altered in GWI. The increased viral richness and alpha diversity correlated positively with gut bacterial dysbiosis and proinflammatory cytokines. Altered virome signature in GWI mice also had a concomitant weakening of intestinal epithelial tight junctions with a significant increase in Claudin-2 protein expression and decrease in ZO1 and Occludin mRNA expression. The altered virome signature in GWI, decreased tight junction protein level was …

Superior Colliculus Lesions Lead To Disrupted Responses To Light In Diurnal Grass Rats (Arvicanthis Niloticus), Andrew J. Gall, Alyssa M. Goodwin, Ohanes S. Khacherian, Laura B. Teal

Faculty Publications

The circadian system regulates daily rhythms of physiology and behavior. Although extraordinary advances have been made to elucidate the brain mechanisms underlying the circadian system in nocturnal species, less is known in diurnal species. Recent studies have shown that retinorecipient brain areas such as the intergeniculate leaflet (IGL) and olivary pretectal nucleus (OPT) are critical for the display of normal patterns of daily activity in diurnal grass rats (Arvicanthis niloticus). Specifically, grass rats with IGL and OPT lesions respond to light in similar ways to intact nocturnal animals. Importantly, both the IGL and OPT project to one another …

Abstraction, Filtration, And Comparison In Patent Law, Michael Risch

Faculty Publications

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3232508

Circulating Obesity-Driven Biomarkers Are Associated With Risk Of Clear Cell Renal Cell Carcinoma: A Two-Stage, Case-Control Study, Qinchuan Wang, Huakang Tu, Meiling Zhu, Dong Liang, Yuanqing Ye, David W. Chang, Yin Long, Xifeng Wu

Faculty Publications

Obesity is one of modifiable risk factors for clear cell renal cell cancer (ccRCC). We aim to identify the association between obesity-driven biomarkers and ccRCC risk. This is a retrospective, two-phase, case-control study involving 682 cases and 733 controls. Obesity-driven biomarkers [gastric inhibitory polypeptide (GIP), C-peptide, insulin, resistin, adipsin, peptide YY, pancreatic polypeptide, interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), plasminogen activator inhibitor-1, monocyte chemoattractant protein 1, lipocalin2, leptin, adiponectin] were measured using the Milliplex method. Multivariate logistic regression was used to assess the associations between biomarkers and ccRCC risk. Results revealed that GIP, C-peptide, IL-6 and TNF-α levels were consistently …

Current Understanding Of West Nile Virus Clinical Manifestations, Immune Responses, Neuroinvasion, And Immunotherapeutic Implications, Fengwei Bai, E. Ashley Thompson, Parminder J.S. Vig, A. Arturo Leis

Faculty Publications

West Nile virus (WNV) is the most common mosquito-borne virus in North America. WNV-associated neuroinvasive disease affects all ages, although elderly and immunocompromised individuals are particularly at risk. WNV neuroinvasive disease has killed over 2300 Americans since WNV entered into the United States in the New York City outbreak of 1999. Despite 20 years of intensive laboratory and clinical research, there are still no approved vaccines or antivirals available for human use. However, rapid progress has been made in both understanding the pathogenesis of WNV and treatment in clinical practices. This review summarizes our current understanding of WNV infection in …

Environmentally Persistent Free Radicals: Linking Air Pollution And Poor Respiratory Health?, Peter D. Sly, Stephania A. Cormier, Slawomir Lomnicki, Jeffrey N. Harding, Keith Grimwood, Griffith University

Faculty Publications

No abstract provided.

Dysbiosis-Associated Enteric Glial Cell Immune-Activation And Redox Imbalance Modulate Tight Junction Protein Expression In Gulf War Illness Pathology, Diana Kimono, Sutapa Sarkar, Muayad Albadrani, Ratanesh K. Seth, Dipro Bose, Ayan Mondal, Yuxi Li, Amar N. Kar, Mitzi Nagarkatti, Prakash Nagarkatti, Kimberly Sullivan, Patricia Janulewicz, Stephen Lasley, Ronnie Horner, Nancy Klimas, Saurabh Chatterjee

Faculty Publications

About 14% of veterans who suffer from Gulf war illness (GWI) complain of some form of gastrointestinal disorder but with no significant markers of clinical pathology. Our previous studies have shown that exposure to GW chemicals resulted in altered microbiome which was associated with damage associated molecular pattern (DAMP) release followed by neuro and gastrointestinal inflammation with loss of gut barrier integrity. Enteric glial cells (EGC) are emerging as important regulators of the gastrointestinal tract and have been observed to change to a reactive phenotype in several functional gastrointestinal disorders such as IBS and IBD. This study is aimed at …

Parasitic Microbiome Project: Grand Challenges, Nolwenn M. Dheilly, Joaquín Martínez Martínez, Karyna Rosario, Paul J. Brindley, Raina N. Fichorava, Jonathan Z. Kaye, Kevin D. Kohl, Laura J. Knoll, Julius Lukeš, Susan L. Perkins, Robert Poulin, Lynn Schriml, Luke R. Thompson

Faculty Publications

No abstract provided.

Effect Of Biochar Amendment On Sorption-Desorption And Dissipation Of 17Α‑Ethinylestradiol In Sandy Loam And Clay Soils, Zhuo Wei, Jim J. Wang, Amy B. Hernandez, Andrea Warren, Jong Hwan Park, Yili Meng, Syam K. Dodla, Changyoon Jeong

Faculty Publications

Animal manure application in agricultural land has caused the release of steroid estrogens in the soil environment and further movement to aquatic systems. The objective of this study was to investigate the effects of biochar addition on sorption-desorption and dissipation behaviors of 17α‑ethinylestradiol (EE2) in two different textured soils. A Commerce sandy loam and a Shakey clay were selected and subjected to sterilization. Soil samples with and without sterilization were reacted with a series of EE2 solutions of different concentrations for sorption followed by desorption and quantification using HPLC-MS/MS. Long-term dissipation of EE2 in the same soils was also evaluated …

Detecting Parasite Associations Within Multi-Species Host And Parasite Communities, Tad A. Dallas, Anna Liisa Laine, Otso Ovaskainen

Faculty Publications

© 2019 The Author(s) Published by the Royal Society. All rights reserved. Understanding the role of biotic interactions in shaping natural communities is a long-standing challenge in ecology. It is particularly pertinent to parasite communities sharing the same host communities and individuals, as the interactions among parasites—both competition and facilitation—may have far-reaching implications for parasite transmission and evolution. Aggregated parasite burdens may suggest that infected host individuals are either more prone to infection, or that infection by a parasite species facilitates another, leading to a positive parasite–parasite interaction. However, parasite species may also compete for host resources, leading to the …

Enabling Stakeholder Decision-Making With Earth Observation And Modeling Data Using Tethys Platform, E. James Nelson, Sarva T. Pulla, Mir A. Matin, Kiran Shakya, Norm Jones, Daniel P. Ames, W. Lee Ellenburg, Kel N. Markert, Cédric H. David, Benjamin F. Zaitchik, Patrick Gatlin, Riley Hales

Faculty Publications

Tethys Platform is an open source framework for developing web-based applications for Earth Observation data. Our experience shows that Tethys significantly lowers the barrier for cloud-based app development, simplifies the process of accessing scalable distributed cloud computing resources and leverages additional software for data and computationally intensive modeling. The Tethys software development kit allows users to create web apps for visualizing, analyzing, and modeling Earth Observation data. Tethys platform provides a collaborative environment for scientists to develop and deploy several Earth Observation web applications across multiple Tethys portals. We work in partnership with leading regional organizations world-wide to help developing …

The Gut-Microbiome In Gulf War Veterans: A Preliminary Report, Patricia A. Janulewicz, Ratanesh K. Seth, Jeffrey M. Carlson, Joy Ajama, Emily Quinn, Timothy Heeren, Nancy Klimas, Steven M. Lasley, Ronnie Horner, Kimberly Sullivan, Saurabh Chatterjee

Faculty Publications

Gulf War Illness (GWI) is a chronic multi-symptom disorder affecting the central nervous system (CNS), immune and gastrointestinal (GI) systems of Gulf War veterans (GWV). We assessed the relationships between GWI, GI symptoms, gut microbiome and inflammatory markers in GWV from the Boston Gulf War Illness Consortium (GWIC). Three groups of GWIC veterans were recruited in this pilot study; GWV without GWI and no gastrointestinal symptoms (controls), GWV with GWI and no gastrointestinal symptoms (GWI-GI), GWV with GWI who reported gastrointestinal symptoms (GW+GI). Here we report on a subset of the first thirteen stool samples analyzed. Results showed significantly different …

Egestion Versus Excretion: A Meta-Analysis Examining Nutrient Release Rates And Ratios Across Freshwater Fauna, Halvor Halvorson, Carla Atkinson

Faculty Publications

In aquatic settings, animals directly affect ecosystem functions through excretion of dissolved nutrients. However, the comparative role of egestion as an animal-mediated nutrient flux remains understudied. We conducted a literature survey and meta-analysis to directly compare nitrogen (N), phosphorus (P), and N:P of egestion compared to excretion rates and ratios across freshwater animals. Synthesizing 215 datasets across 47 animal species (all primary consumers or omnivores), we show that the total N and P egestion rates exceed inorganic N and P excretion rates but not total N and P excretion rates, and that proportions of P egested compared to excreted depend …