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Comparison Of An Intermittent, Short-Dawn/Dusk Photoperiod With An Increasing, Long-Dawn/Dusk Photoperiod On Broiler Growth, Stress, And Welfare, Jill R. Nelson, Joey L. Bray, Juliette Delabbio, Gregory S. Archer Jan 2020

Comparison Of An Intermittent, Short-Dawn/Dusk Photoperiod With An Increasing, Long-Dawn/Dusk Photoperiod On Broiler Growth, Stress, And Welfare, Jill R. Nelson, Joey L. Bray, Juliette Delabbio, Gregory S. Archer

Faculty Publications

Photoperiod has been shown to significantly affect broiler performance. However, the effects of the traditional 1-min dimming period on broiler growth and welfare are unclear. In this study, 4 consecutive trials were conducted to compare the effects of an intermittent, short-dawn/dusk photoperiod (ISD) to an increasing, long-dawn/dusk photoperiod (ILD) on broiler growth, stress, and welfare. Straight run day-of-hatch Ross 708 × Ross 708 broilers were placed in 1 of 4 commercial broiler barns (2 b of 26,200 birds each per treatment) and grown to 45 D of age. The photoperiod in the ISD treatment consisted of 24L:0D day 0 to …

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Bias And Misrepresentation Of Science Undermines Productive Discourse On Animal Welfare Policy: A Case Study, Kelly Jaakkola, Jason N. Bruck, Richard C. Connor, Stephen H. Montgomery, Stephanie L. King Jan 2020

Bias And Misrepresentation Of Science Undermines Productive Discourse On Animal Welfare Policy: A Case Study, Kelly Jaakkola, Jason N. Bruck, Richard C. Connor, Stephen H. Montgomery, Stephanie L. King

Faculty Publications

Reliable scientific knowledge is crucial for informing legislative, regulatory, and policy decisions in a variety of areas. To that end, scientific reviews of topical issues can be invaluable tools for informing productive discourse and decision-making, assuming these reviews represent the target body of scientific knowledge as completely, accurately, and objectively as possible. Unfortunately, not all reviews live up to this standard. As a case in point, Marino et al.’s review regarding the welfare of killer whales in captivity contains methodological flaws and misrepresentations of the scientific literature, including problematic referencing, overinterpretation of the data, misleading word choice, and biased argumentation. …

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Can The Fut 2 Gene Variant Have An Effect On The Body Weight Of Patients Undergoing Bariatric Surgery? - Preliminary, Exploratory Study, Natalia Komorniak, Alexandra Martynova-Van Kley, Armen Nalian, Wiktoria Wardziukiewicz, Karolina Skoniecznaa-Zydecka, Daniel Styburski, Joanna Palma, Bartosz Kowalewski, Krzysztof Kaseja, Ewa Stachowska Jan 2020

Can The Fut 2 Gene Variant Have An Effect On The Body Weight Of Patients Undergoing Bariatric Surgery? - Preliminary, Exploratory Study, Natalia Komorniak, Alexandra Martynova-Van Kley, Armen Nalian, Wiktoria Wardziukiewicz, Karolina Skoniecznaa-Zydecka, Daniel Styburski, Joanna Palma, Bartosz Kowalewski, Krzysztof Kaseja, Ewa Stachowska

Faculty Publications

Background: The FUT2 gene (Se gene) encoding the enzyme α-1,2-L-fucosyltransferase 2 seems to have a significant effect on the number and type of bacteria colonizing the intestines. Methods: In a group of 19 patients after bariatric surgery, the polymorphism (rs601338) of FUT2 gene was analyzed in combination with body mass reduction, intestinal microbiome (16S RNA sequencing), and short chain fatty acids (SCFA) measurements in stools. Results: Among the secretors (Se/Se polymorphism of the FUT2 gene rs601338, carriers of GG variant), correlations between waist-hip ratio (WHR) and propionate content and an increase in Prevotella, Escherichia, Shigella, and Bacteroides were observed. On …

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Specialty Drugs And The Health Care Cost Crisis, Sharona Hoffman, Isaac D. Buck Jan 2020

Specialty Drugs And The Health Care Cost Crisis, Sharona Hoffman, Isaac D. Buck

Faculty Publications

Specialty drugs, often dispensed by specialty pharmacies, are among the most expensive drugs on the market. They are significant contributors to the American health care cost problem, but in many ways they escape public and regulatory scrutiny. Surprisingly, medications are designated as specialty drugs by pharmacy benefit managers (PBMs), entities that are part of the insurance industry, rather than by the Food and Drug Administration or medical authorities.

Specialty drugs have thus far received little attention in the legal literature. Yet, they raise important legal and regulatory questions. For example, there are no federal government rules (and only a handful …

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Electrophysiological And Motor Responses To Chemosensory Stimuli In Isolated Cephalopod Arms, Kaitlyn E. Fouke, Heather J. Rhodes Jan 2020

Electrophysiological And Motor Responses To Chemosensory Stimuli In Isolated Cephalopod Arms, Kaitlyn E. Fouke, Heather J. Rhodes

Faculty Publications

No abstract provided.

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Activity Level-Predation Risk Tradeoff In A Tadpole Guild: Implications For Community Organization Along The Hydroperiod Gradient, Nicholas C. Schiwitz, Christopher M. Schalk, Daniel Saenz Jan 2020

Activity Level-Predation Risk Tradeoff In A Tadpole Guild: Implications For Community Organization Along The Hydroperiod Gradient, Nicholas C. Schiwitz, Christopher M. Schalk, Daniel Saenz

Faculty Publications

Increasing activity levels permit greater food intake for use towards growth and reproduction, consequently increasing predation risk via increased detection. Larval anurans are models to examine activity level-predation risk tradeoffs, as they occupy a variety of lentic habitats that impose constraints on the distribution and abundance of species. Ephemeral ponds have a low abundance and diversity of predators and as a result tadpole species tend to have high foraging rates for rapid development. Permanent ponds generally possess a greater diversity and abundance of predators and tadpoles inhabiting these locations tend to have low activity rates or chemical defenses to minimize …

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Big Data And Its Visualization With Fog Computing, Richard S. Segall, Gao Niu Jan 2020

Big Data And Its Visualization With Fog Computing, Richard S. Segall, Gao Niu

Faculty Publications

Big Data is data sets that are so voluminous and complex that traditional data processing application software are inadequate to deal with them. This article discusses what is Big Data, and its characteristics, and how this information revolution of Big Data is transforming our lives and the new technology and methodologies that have been developed to process data of these huge dimensionalities. Big Data can be discrete or a continuous stream of data, and can be accessed using many types and kinds of computing devices ranging from supercomputers, personal work stations, to mobile devices and tablets. Discussion is presented of …

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Anthropogenic, Direct Pressures On Coastal Wetlands, A Newton, J Icely, S Cristina, G M. Perillo, A Newton, D Ashan, S Cragg, Y M. Luo, C Tu, Y Li, H B. Zhang, R Ramesh, D L. Forbes, C Solidoro, B Bejaoui, S Gao, R Pastres, H Kelsey, D Taillie, N Nhan, A C. Brito, L I. De, K U. R, C Jan 2020

Anthropogenic, Direct Pressures On Coastal Wetlands, A Newton, J Icely, S Cristina, G M. Perillo, A Newton, D Ashan, S Cragg, Y M. Luo, C Tu, Y Li, H B. Zhang, R Ramesh, D L. Forbes, C Solidoro, B Bejaoui, S Gao, R Pastres, H Kelsey, D Taillie, N Nhan, A C. Brito, L I. De, K U. R, C

Faculty Publications

Coastal wetlands, such as saltmarshes and mangroves that fringe transitional waters, deliver important ecosystem services that support human development. Coastal wetlands are complex social-ecological systems that occur at all latitudes, from polar regions to the tropics. This overview covers wetlands in five continents. The wetlands are of varying size, catchment size, human population and stages of economic development. Economic sectors and activities in and around the coastal wetlands and their catchments exert multiple, direct pressures. These pressures affect the state of the wetland environment, ecology and valuable ecosystem services. All the coastal wetlands were found to be affected in some …

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Influence Of Macrobenthos (Meretrix Meretrix Linnaeus) On Erosion-Accretion Processes In Intertidal Flats: A Case Study From A Cultivation Zone, B. Shi, P.D. Pratolongo, Y. Du, J. Li, S.L. Yang, J. Wu, K. Xu, Y.P. Wang Jan 2020

Influence Of Macrobenthos (Meretrix Meretrix Linnaeus) On Erosion-Accretion Processes In Intertidal Flats: A Case Study From A Cultivation Zone, B. Shi, P.D. Pratolongo, Y. Du, J. Li, S.L. Yang, J. Wu, K. Xu, Y.P. Wang

Faculty Publications

No abstract provided.

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What Is Open Source Software (Oss) And What Is Big Data?, Richard S. Segall Jan 2020

What Is Open Source Software (Oss) And What Is Big Data?, Richard S. Segall

Faculty Publications

This chapter discusses what Open Source Software is and its relationship to Big Data and how it differs from other types of software and its software development cycle. Open source software (OSS) is a type of computer software in which source code is released under a license in which the copyright holder grants users the rights to study, change, and distribute the software to anyone and for any purpose. Big Data are data sets that are so voluminous and complex that traditional data processing application software are inadequate to deal with them. Big data can be discrete or a continuous …

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New Technologies And Old Treaties, Bryant Walker Smith Jan 2020

New Technologies And Old Treaties, Bryant Walker Smith

Faculty Publications

Every road vehicle must have a driver able to control it while in motion. These requirements, explicit in two important conventions on road traffic, have an uncertain relationship to the automated motor vehicles that are currently under development—often colloquially called “self-driving” or “driverless.” The immediate legal and policy questions are straightforward: Are these requirements consistent with automated driving and, if not, how should the inconsistency be resolved? More subtle questions go directly to international law’s role in a world that artificial intelligence is helping to rapidly change: In a showdown between a promising new technology and an entrenched treaty regime, …

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Legislative History In The Modern Congress, Jesse M. Cross Jan 2020

Legislative History In The Modern Congress, Jesse M. Cross

Faculty Publications

A central debate in the field of legislation has asked: how reliable are the different types of legislative history? Yet there has been no understanding, throughout this debate, of who inside Congress drafts this legislative history. This is surprising, given the common intuition that authorship is a key indicator of reliability.

In response, this Article presents the results of an original empirical study—one that illuminates this unknown dimension of Congress, uncovering the actors and processes that produce modern legislative history. For this study, the author conducted interviews with congressional staffers drawn from both parties, both chambers of Congress, and numerous …

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Rethinking The Conflicts Revolution In Personal Jurisdiction, Jesse M. Cross Jan 2020

Rethinking The Conflicts Revolution In Personal Jurisdiction, Jesse M. Cross

Faculty Publications

It is widely acknowledged that, from roughly 1940 to 1970, a revolution occurred in Conflicts of Law. Referred to as the “Conflicts revolution,” this movement remade nearly every legal test in the field. According to conventional wisdom, this revolution rejected the same idea in each instance: namely, that Conflicts tests should be grounded in a theory of sovereignty. Instead, the argument goes, it pivoted the field to pragmatic tests that focus on practicality, fairness, and convenience.

As this Article explains, this conventional wisdom is incorrect. It misunderstands the intellectual revolution that remade the field, and it has generated needless confusion …

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A Comprehensive Framework For Conflict Preemption In Federal Insolvency Proceedings, Robert W. Miller Jan 2020

A Comprehensive Framework For Conflict Preemption In Federal Insolvency Proceedings, Robert W. Miller

Faculty Publications

No abstract provided.

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Methods For Broad-Scale Plant Phenology Assessments Using Citizen Scientists’ Photographs, Vijay V. Barve, Laura Brenskelle, Daijiang Li, Brian J. Stucky, Narayani V. Barve, Maggie M. Hantak, Bryan S. Mclean, Daniel J. Paluh, Jessica A. Oswald, Michael W. Belitz, Ryan A. Folk, Robert P. Guralnick Jan 2020

Methods For Broad-Scale Plant Phenology Assessments Using Citizen Scientists’ Photographs, Vijay V. Barve, Laura Brenskelle, Daijiang Li, Brian J. Stucky, Narayani V. Barve, Maggie M. Hantak, Bryan S. Mclean, Daniel J. Paluh, Jessica A. Oswald, Michael W. Belitz, Ryan A. Folk, Robert P. Guralnick

Faculty Publications

© 2020 Barve et al. Applications in Plant Sciences is published by Wiley Periodicals, Inc. on behalf of the Botanical Society of America Premise: Citizen science platforms for sharing photographed digital vouchers, such as iNaturalist, are a promising source of phenology data, but methods and best practices for use have not been developed. Here we introduce methods using Yucca flowering phenology as a case study, because drivers of Yucca phenology are not well understood despite the need to synchronize flowering with obligate pollinators. There is also evidence of recent anomalous winter flowering events, but with unknown spatiotemporal extents. Methods: We …

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Impaired Purine Homeostasis Plays A Primary Role In Trimethoprim-Mediated Induction Of Virulence Genes In Burkholderia Thailandensis, Sudarshan S. Thapa, Anne Grove Jan 2020

Impaired Purine Homeostasis Plays A Primary Role In Trimethoprim-Mediated Induction Of Virulence Genes In Burkholderia Thailandensis, Sudarshan S. Thapa, Anne Grove

Faculty Publications

© 2020 John Wiley & Sons Ltd One of the most commonly prescribed antibiotics against Burkholderia infections is co-trimoxazole, a cocktail of trimethoprim and sulfamethoxazole. Trimethoprim elicits an upregulation of the mal gene cluster, which encodes proteins involved in synthesis of the cytotoxic polyketide malleilactone; trimethoprim does so by increasing expression of the malR gene, which encodes the activator MalR. We report that B. thailandensis grown on trimethoprim exhibited increased virulence against Caenorhabditis elegans. This enhanced virulence correlated with an increase in expression of the mal gene cluster. Notably, inhibition of xanthine dehydrogenase by addition of allopurinol led to similar …

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Modeling The Effects Of Trait-Mediated Dispersal On Coexistence Of Mutualists, James T. Cronin, Jerome Goddard, Amila Muthunayake, Ratnasingham Shivaji Jan 2020

Modeling The Effects Of Trait-Mediated Dispersal On Coexistence Of Mutualists, James T. Cronin, Jerome Goddard, Amila Muthunayake, Ratnasingham Shivaji

Faculty Publications

© 2020 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) Even though mutualistic interactions are ubiquitous in nature, we are still far from making good predictions about the fate of mutualistic communities under threats such as habitat fragmentation and climate change. Fragmentation often causes declines in abundance of a species due to increased susceptibility to edge effects between remnant habitat patches and lower quality “matrix” surrounding these focal patches. It has been argued that ecological communities are replete with trait-mediated indirect effects, and that these effects …

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Modeling The Effects Of Density Dependent Emigration, Weak Allee Effects, And Matrix Hostility On Patch-Level Population Persistence, James T. Cronin, Nalin Fonseka, Jerome Goddard, Jackson Leonard, Ratnasingham Shivaji Jan 2020

Modeling The Effects Of Density Dependent Emigration, Weak Allee Effects, And Matrix Hostility On Patch-Level Population Persistence, James T. Cronin, Nalin Fonseka, Jerome Goddard, Jackson Leonard, Ratnasingham Shivaji

Faculty Publications

© 2020 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) The relationship between conspecific density and the probability of emigrating from a patch can play an essential role in determining the population-dynamic consequences of an Allee effect. In this paper, we model a population that inside a patch is diffusing and growing according to a weak Allee effect per-capita growth rate, but the emigration probability is dependent on conspecific density. The habitat patch is one-dimensional and is surrounded by a tuneable hostile matrix. We consider five …

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Taxonomic Resolution Affects Host-Parasite Association Model Performance, Tad A. Dallas, Daniel J. Becker Jan 2020

Taxonomic Resolution Affects Host-Parasite Association Model Performance, Tad A. Dallas, Daniel J. Becker

Faculty Publications

© 2020 Georg Thieme Verlag. All rights reserved. Identifying the factors that structure host-parasite interactions is fundamental to understand the drivers of species distributions and to predict novel cross-species transmission events. More phylogenetically related host species tend to have more similar parasite associations, but parasite specificity may vary as a function of transmission mode, parasite taxonomy, or life history. Accordingly, analyses that attempt to infer host-parasite associations using combined data on different parasite groups may perform quite differently relative to analyses on each parasite subset. In essence, are more data always better when predicting host-parasite associations, or does parasite taxonomic …

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Behavioral, Morphological, And Ecological Trait Evolution In Two Clades Of New World Sparrows (Aimophila And Peucaea, Passerellidae), Carla Cicero, Nicholas A. Mason, Lauryn Benedict, James D. Rising Jan 2020

Behavioral, Morphological, And Ecological Trait Evolution In Two Clades Of New World Sparrows (Aimophila And Peucaea, Passerellidae), Carla Cicero, Nicholas A. Mason, Lauryn Benedict, James D. Rising

Faculty Publications

Copyright 2020 Cicero et al. The New World sparrows (Passerellidae) are a large, diverse group of songbirds that vary in morphology, behavior, and ecology. Thus, they are excellent for studying trait evolution in a phylogenetic framework. We examined lability versus conservatism in morphological and behavioral traits in two related clades of sparrows (Aimophila, Peucaea), and assessed whether habitat has played an important role in trait evolution. We first inferred a multi-locus phylogeny which we used to reconstruct ancestral states, and then quantified phylogenetic signal among morphological and behavioral traits in these clades and in New World sparrows more broadly. Behavioral …

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Improving Natural Product Research Translation: From Source To Clinical Trial, Barbara C. Sorkin, Adam J. Kuszak, Gregory Bloss, Naomi K. Fukagawa, Freddie Ann Hoffman, Mahtab Jafari, Bruce Barrett, Paula N. Brown, Frederic D. Bushman, Steven J. Casper, Floyd H. Chilton, Christopher S. Coffey, Mario G. Ferruzzi, D. Craig Hopp, Mairead Kiely, Daniel Lakens, John B. Macmillan, David O. Meltzer, Marco Pahor, Jeffrey Paul, Kathleen Pritchett-Corning, Sara K. Quinney, Barbara Rehermann, Kenneth D.R. Setchell, Nisha S. Sipes, Jacqueline M. Stephens, D. Lansing Taylor, Hervé Tiriac, Michael A. Walters, Dan Xi, Giovanna Zappalá, Guido F. Pauli Jan 2020

Improving Natural Product Research Translation: From Source To Clinical Trial, Barbara C. Sorkin, Adam J. Kuszak, Gregory Bloss, Naomi K. Fukagawa, Freddie Ann Hoffman, Mahtab Jafari, Bruce Barrett, Paula N. Brown, Frederic D. Bushman, Steven J. Casper, Floyd H. Chilton, Christopher S. Coffey, Mario G. Ferruzzi, D. Craig Hopp, Mairead Kiely, Daniel Lakens, John B. Macmillan, David O. Meltzer, Marco Pahor, Jeffrey Paul, Kathleen Pritchett-Corning, Sara K. Quinney, Barbara Rehermann, Kenneth D.R. Setchell, Nisha S. Sipes, Jacqueline M. Stephens, D. Lansing Taylor, Hervé Tiriac, Michael A. Walters, Dan Xi, Giovanna Zappalá, Guido F. Pauli

Faculty Publications

© 2019 Federation of American Societies for Experimental Biology While great interest in health effects of natural product (NP) including dietary supplements and foods persists, promising preclinical NP research is not consistently translating into actionable clinical trial (CT) outcomes. Generally considered the gold standard for assessing safety and efficacy, CTs, especially phase III CTs, are costly and require rigorous planning to optimize the value of the information obtained. More effective bridging from NP research to CT was the goal of a September, 2018 transdisciplinary workshop. Participants emphasized that replicability and likelihood of successful translation depend on rigor in experimental design, …

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Novel Resistant Starch Type 4 Products Of Different Starch Origins, Production Methods, And Amounts Are Not Equally Fermented When Fed To Sprague-Dawley Rats, Diana B. Coulon, Ryan Page, Anne M. Raggio, Justin Guice, Brain Marx, Vishnupriya Gourineni, Maria L. Stewart, Michael J. Keenan Jan 2020

Novel Resistant Starch Type 4 Products Of Different Starch Origins, Production Methods, And Amounts Are Not Equally Fermented When Fed To Sprague-Dawley Rats, Diana B. Coulon, Ryan Page, Anne M. Raggio, Justin Guice, Brain Marx, Vishnupriya Gourineni, Maria L. Stewart, Michael J. Keenan

Faculty Publications

© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Scope: The possible mechanisms of production of four novel resistant starch type 4 (RS4) products for total cecal fermentation in an in vivo rodent model are evaluated. Methods and results: Forty weanling rats are randomly assigned to five groups (n = 8) for a 3-week study. Starches are the RS type 4 products, as 10% of weight of RS diets (RSA–RSD), and AMIOCA starch (100% amylopectin) comprises 53.6% weight of control (CON) and 43.6% weight of RS diets. The RS products vary by percent purity and origin (potato, corn, tapioca). At …

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The Landscape Of Accessible Chromatin In Bovine Oocytes And Early Embryos, Hao Ming, Jiangwen Sun, Rolando Pasquariello, Lauren Gatenby, Jason Herrick, Ye Yuan, Carlos Pinto, Kenneth R. Bondioli, Rebecca L. Krisher, Zongliang Jiang Jan 2020

The Landscape Of Accessible Chromatin In Bovine Oocytes And Early Embryos, Hao Ming, Jiangwen Sun, Rolando Pasquariello, Lauren Gatenby, Jason Herrick, Ye Yuan, Carlos Pinto, Kenneth R. Bondioli, Rebecca L. Krisher, Zongliang Jiang

Faculty Publications

© 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. Chromatin reorganization governs the regulation of gene expression during preimplantation development. However, the landscape of chromatin dynamics in this period has not been explored in bovine. In this study, we constructed a genome-wide map of accessible chromatin in bovine oocytes and early embryos using an improved assay for transposase-accessible chromatin with high-throughput sequencing (ATAC-seq) which revealed unique features of the accessible chromatin during bovine early embryo development. We found that chromatin accessibility is low in oocytes and 2-/4-cell embryos, followed by a significant increase in embryos during …

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Novel Resistant Starch Type 4 Products Of Different Starch Origins, Production Methods, And Amounts Are Not Equally Fermented When Fed To Sprague-Dawley Rats, Diana B. Coulon, Ryan Page, Anne M. Raggio, Justin Guice, Brain Marx, Vishnupriya Gourineni, Maria L. Stewart, Michael J. Keenan Jan 2020

Novel Resistant Starch Type 4 Products Of Different Starch Origins, Production Methods, And Amounts Are Not Equally Fermented When Fed To Sprague-Dawley Rats, Diana B. Coulon, Ryan Page, Anne M. Raggio, Justin Guice, Brain Marx, Vishnupriya Gourineni, Maria L. Stewart, Michael J. Keenan

Faculty Publications

© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Scope: The possible mechanisms of production of four novel resistant starch type 4 (RS4) products for total cecal fermentation in an in vivo rodent model are evaluated. Methods and results: Forty weanling rats are randomly assigned to five groups (n = 8) for a 3-week study. Starches are the RS type 4 products, as 10% of weight of RS diets (RSA–RSD), and AMIOCA starch (100% amylopectin) comprises 53.6% weight of control (CON) and 43.6% weight of RS diets. The RS products vary by percent purity and origin (potato, corn, tapioca). At …

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The Landscape Of Accessible Chromatin In Bovine Oocytes And Early Embryos, Hao Ming, Jiangwen Sun, Rolando Pasquariello, Lauren Gatenby, Jason Herrick, Ye Yuan, Carlos Pinto, Kenneth R. Bondioli, Rebecca L. Krisher, Zongliang Jiang Jan 2020

The Landscape Of Accessible Chromatin In Bovine Oocytes And Early Embryos, Hao Ming, Jiangwen Sun, Rolando Pasquariello, Lauren Gatenby, Jason Herrick, Ye Yuan, Carlos Pinto, Kenneth R. Bondioli, Rebecca L. Krisher, Zongliang Jiang

Faculty Publications

© 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. Chromatin reorganization governs the regulation of gene expression during preimplantation development. However, the landscape of chromatin dynamics in this period has not been explored in bovine. In this study, we constructed a genome-wide map of accessible chromatin in bovine oocytes and early embryos using an improved assay for transposase-accessible chromatin with high-throughput sequencing (ATAC-seq) which revealed unique features of the accessible chromatin during bovine early embryo development. We found that chromatin accessibility is low in oocytes and 2-/4-cell embryos, followed by a significant increase in embryos during …

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Charros: How Mexican Cowboys Are Remapping Race And American Identity, Andrew Sluyter Jan 2020

Charros: How Mexican Cowboys Are Remapping Race And American Identity, Andrew Sluyter

Faculty Publications

No abstract provided.

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Informe Tecnico De Los Trabajos De Campo Del Proyecto De Investigación Arqueológica Cerro San Isidro, Valle De Nepeña, Costa De Ancash -- Temporada 2019, David Chicoine, Jeisen Navarro Jan 2020

Informe Tecnico De Los Trabajos De Campo Del Proyecto De Investigación Arqueológica Cerro San Isidro, Valle De Nepeña, Costa De Ancash -- Temporada 2019, David Chicoine, Jeisen Navarro

Faculty Publications

No abstract provided.

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Phlebotomines (Diptera: Psychodidae) From A Urban Park Of Belém, Pará State, Northern Brazil And Potential Implications In The Transmission Of American Cutaneous Leishmaniasis, Yetsenia D.V. Sánchez Uzcátegui, Thiago Vasconcelos Dos Santos, Fernando T. Silveira, Patricia K.S. Ramos, Eduardo José M. Dos Santos, Marinete M. Póvoa, Lane Foil Jan 2020

Phlebotomines (Diptera: Psychodidae) From A Urban Park Of Belém, Pará State, Northern Brazil And Potential Implications In The Transmission Of American Cutaneous Leishmaniasis, Yetsenia D.V. Sánchez Uzcátegui, Thiago Vasconcelos Dos Santos, Fernando T. Silveira, Patricia K.S. Ramos, Eduardo José M. Dos Santos, Marinete M. Póvoa, Lane Foil

Faculty Publications

© 2019 The Author(s) 2019. Published by Oxford University Press on behalf of Entomological Society of America. In urban ecotourism parks, the life cycle of American cutaneous leishmaniasis (ACL) agents can remain established, where phlebotomines may comprise potential risks for visitors. The present study aimed to survey the phlebotomine fauna of a forest park 'Bosque Rodriques Alves-Jardim Botânico da Amazônia' (BRAJBA), in the urban area of Belém, Brazil. The park was monthly surveyed in 2018 using CDC light traps placed in ground and canopy strata. Leishmania spp. isolated from dissected females were characterized by polymerase chain reaction-restriction fragment length polymorphism …

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Tropism, Pathology, And Transmission Of Equine Parvovirus-Hepatitis, Joy Ellen Tomlinson, Mason Jager, Alyssa Struzyna, Melissa Laverack, Lisa Ann Fortier, Edward Dubovi, Lane D. Foil, Peter D. Burbelo, Thomas J. Divers, Gerlinde R. Van De Walle Jan 2020

Tropism, Pathology, And Transmission Of Equine Parvovirus-Hepatitis, Joy Ellen Tomlinson, Mason Jager, Alyssa Struzyna, Melissa Laverack, Lisa Ann Fortier, Edward Dubovi, Lane D. Foil, Peter D. Burbelo, Thomas J. Divers, Gerlinde R. Van De Walle

Faculty Publications

© 2020, © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd. Equine parvovirus-hepatitis (EqPV-H) has recently been associated with cases of Theiler's disease, a form of fulminant hepatic necrosis in horses. To assess whether EqPV-H is the cause of Theiler's disease, we first demonstrated hepatotropism by PCR on tissues from acutely infected horses. We then experimentally inoculated horses with EqPV-H and 8 of 10 horses developed hepatitis. One horse showed clinical signs of liver failure. The onset of hepatitis was temporally associated with seroconversion and …

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Hepatic Ikkε Expression Is Dispensable For High-Fat Feeding-Induced Increases In Liver Lipid Content And Alterations In Glucose Tolerance, J. Jason Collier, Heidi M. Batdorf, Tamra M. Mendoza, David H. Burk, Thomas M. Martin, Jingying Zhang, Randall L. Mynatt, Susan J. Burke Jan 2020

Hepatic Ikkε Expression Is Dispensable For High-Fat Feeding-Induced Increases In Liver Lipid Content And Alterations In Glucose Tolerance, J. Jason Collier, Heidi M. Batdorf, Tamra M. Mendoza, David H. Burk, Thomas M. Martin, Jingying Zhang, Randall L. Mynatt, Susan J. Burke

Faculty Publications

© 2020 the American Physiological Society. There are endocrine and immunological changes that occur during onset and progression of the overweight and obese states. The inhibitor of nuclear factor-κB kinase-ε (IKKε) was originally described as an inducible protein kinase; whole body gene deletion or systemic pharmaceutical targeting of this kinase improved insulin sensitivity and glucose tolerance in mice. To investigate the primary sites of action associated with IKKε during weight gain, we describe the first mouse line with conditional elimination of IKKε in the liver (IKKεAlb-/-). IKKεAlb-/- mice and littermate controls gain weight, show similar changes in body composition, and …

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