Digital Commons Network^™

Review: Enhancing Intramuscular Fat Development Via Targeting Fibro-Adipogenic Progenitor Cells In Meat Animals, X. Li, X. Fu, G. Yang, M. Du

Faculty Publications

© 2019 The Animal Consortium. In the livestock industry, subcutaneous and visceral fat pads are considered as wastes, while intramuscular fat or marbling fat is essential for improving flavor and palatability of meat. Thus, strategies for optimizing fat deposition are needed. Intramuscular adipocytes provide sites for lipid deposition and marbling formation. In the present article, we addressed the origin and markers of intramuscular adipocyte progenitors-fibro-adipogenic progenitors (FAPs), as well as the latest progresses in mechanisms regulating the proliferation and differentiation of intramuscular FAPs. Finally, by targeting intramuscular FAPs, possible nutritional manipulations to improve marbling fat deposition are discussed. Despite recent …

Ncapg Dynamically Coordinates The Myogenesis Of Fetal Bovine Tissue By Adjusting Chromatin Accessibility, Xin Hu, Yishen Xing, Xing Fu, Qiyuan Yang, Ling Ren, Yahui Wang, Qian Li, Junya Li, Lupei Zhang

Faculty Publications

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. NCAPG is a subunit of condensin I that plays a crucial role in chromatin condensation during mitosis. NCAPG has been demonstrated to be associated with farm animal growth traits. However, its role in regulating myoblast differentiation is still unclear. We used myoblasts derived from fetal bovine tissue as an in vitro model and found that NCAPG was expressed during myogenic differentiation in the cytoplasm and nucleus. Silencing NCAPG prolonged the mitosis and impaired the differentiation due to increased myoblast apoptosis. After 1.5 days of differentiation, silencing NCAPG enhanced muscle-specific gene expression. …

Genomic Analysis For Virulence Determinants In Feline Herpesvirus Type-1 Isolates, Andrew C. Lewin, Lyndon M. Coghill, Gillian J. Mclellan, Ellison Bentley, Konstantin G. Kousoulas

Faculty Publications

© 2019, Springer Science+Business Media, LLC, part of Springer Nature. Feline herpesvirus type 1 (FHV-1) is a widespread cause of respiratory and ocular disease in domestic cats. A spectrum of disease severity is observed in host animals, but there has been limited prior investigation into viral genome factors which could be responsible. Stocks of FHV-1 were established from oropharyngeal swabs obtained from twenty-five cats with signs of infection housed in eight animal shelters around the USA. A standardized numerical host clinical disease severity scoring scheme was used for each cat from which an isolate was obtained. Illumina MiSeq was used …

Intramuscular Vaccination Of Mice With The Human Herpes Simplex Virus Type-1(Hsv-1) Vc2 Vaccine, But Not Its Parental Strain Hsv-1 (F) Confers Full Protection Against Lethal Ocular Hsv-1 (Mckrae) Pathogenesis, Shan K. Naidu, Rafiq Nabi, Nagarjuna R. Cheemarla, Brent A. Stanfield, Paul J. Rider, Nithya Jambunathan, Vladimir N. Chouljenko, Renee Carter, Fabio Del Piero, Ingeborg Langohr, Konstantin G. Kousoulas

Faculty Publications

Copyright: © 2020 Naidu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Herpes simplex virus type-1 (HSV-1) can cause severe ocular infection and blindness. We have previously shown that the HSV-1 VC2 vaccine strain is protective in mice and guinea pigs against genital herpes infection following vaginal challenge with HSV-1 or HSV-2. In this study, we evaluated the efficacy of VC2 intramuscular vaccination in mice against herpetic keratitis following ocular challenge with …

Perinatal Maternal Antibiotic Exposure Augments Lung Injury In Offspring In Experimental Bronchopulmonary Dysplasia, Kent A. Willis, David T. Siefker, Michael M. Aziz, Catrina T. White, Naiha Mussarat, Charles K. Gomes, Amandeep Bajwa, Joseph F. Pierre, Stephania A. Cormier, Ajay J. Talati

Faculty Publications

Copyright © 2020 the American Physiological Society. During the newborn period, intestinal commensal bacteria influence pulmonary mucosal immunology via the gut-lung axis. Epidemiological studies have linked perinatal antibiotic exposure in human newborns to an increased risk for bronchopulmonary dysplasia, but whether this effect is mediated by the gut-lung axis is unknown. To explore antibiotic disruption of the newborn gut-lung axis, we studied how perinatal maternal antibiotic exposure influenced lung injury in a hyperoxia-based mouse model of bronchopulmonary dysplasia. We report that disruption of intestinal commensal colonization during the perinatal period promotes a more severe bronchopulmonary dysplasia phenotype characterized by increased …

Mice Without A Microbiome Are Partially Protected From Lung Injury By Hyperoxia, Kent A. Willis, Joseph F. Pierre, Stephania A. Cormier, Ajay J. Talati

Faculty Publications

No abstract provided.

Respiratory Syncytial Virus Disease Severity Is Associated With Distinct Cd8+ T-Cell Profiles, David T. Siefker, Luan Vu, Dahui You, Andrew Mcbride, Ryleigh Taylor, Tamekia L. Jones, John Devincenzo, Stephania A. Cormier

Faculty Publications

Copyright © 2020 by the American Thoracic Society. Rationale: Respiratory syncytial virus (RSV) causes significant morbidity and mortality in infants worldwide. Although T-helper type 2 (Th2) cell pathology is implicated in severe disease, the mechanisms underlying the development of immunopathology are incompletely understood. Objectives: We aimed to identify local immune responses associated with severe RSV in infants. Our hypothesis was that disease severity would correlate with enhanced Th2 cellular responses. Methods: Nasal aspirates were collected from infants hospitalized with severe (admitted to the pediatric ICU) or moderate (maintained in the general ward) RSV disease at 5 to 9 days after …

Maize Yield In Smallholder Agriculture System-An Approach Integrating Socioeconomic And Crop Management Factors, Sudarshan Dutta, Somsubhra Chakraborty, Rupak Goswami, Hirak Banerjee, Kaushik Majumdar, Bin Li, M. L. Jat

Faculty Publications

Yield gaps of maize (Zea mays L.) in the smallholder farms of eastern India are outcomes of a complex interplay of climatic variations, soil fertility gradients, socio-economic factors, and differential management intensities. Several machine learning approaches were used in this study to investigate the relative influences of multiple biophysical, socio-economic, and crop management features in determining maize yield variability using several machine learning approaches. Soil fertility status was assessed in 180 farms and paired with the surveyed data on maize yield, socio-economic conditions, and agronomic management. The C&RT relative variable importance plot identified farm size, total labor, soil factors, seed …

Rubusoside-Assisted Solubilization Of Poorly Soluble C6-Ceramide For A Pilot Pharmacokinetic Study, Jianzhong Chen, Sachin K. Khiste, Xiaomei Fu, Kartik R. Roy, Yixuan Dong, Jian Zhang, Mei Liu, Yong Yu Liu, Zhijun Liu

Faculty Publications

Although C6-Ceramide has attracted much attention as a possible tumor suppressor, the delivery of C6-Ceramide is still challenging due to its inherent hydrophobicity and insolubility. In this study we explored the use of a natural compound rubusoside (RUB) as a solubilizer to enhance the solubility of a fluorescence-labeled C6-Ceramide (NBD C6-Ceramide) and to characterize its pharmacokinetics and tissue distribution in an animal model. RUB significantly enhanced the solubility of NBD C6-Ceramide by forming nanomicelles, and efficiently delivered NBD C6-Ceramide in rats by oral and intravenous administration. RUB loaded 1.96 % of NBD C6-Ceramide in the nanomicelles and solubilized it to …

Ceramide–Rubusoside Nanomicelles, A Potential Therapeutic Approach To Target Cancers Carrying P53 Missense Mutations, Sachin K. Khiste, Zhijun Liu, Kartik R. Roy, Mohammad B. Uddin, Salman B. Hosain, Xin Gu, Sami Nazzal, Ronald A. Hill, Yong Yu Liu

Faculty Publications

Ceramide (Cer) is an active cellular sphingolipid that can induce apoptosis or proliferation-arrest of cancer cells. Nanoparticle-based delivery offers an effective approach for overcoming bioavailability and biopharmaceutics issues attributable to the pronounced hydrophobicity of Cer. Missense mutations of the protein p53, which have been detected in approximately 42% of cancer cases, not only lose the tumor suppression activity of wild-type p53, but also gain oncogenic functions promoting tumor progression and drug resistance. Our previous works showed that cellular Cer can eradicate cancer cells that carry a p53 deletion-mutation by modulating alternative pre-mRNA splicing, restoring wild-type p53 protein expression. Here, we …

Trans-Disciplinary Responses To Climate Change: Lessons From Rice-Based Systems In Asia, Jon Hellin, Jean Balié, Eleanor Fisher, Ajay Kohli, Melanie Connor, Sudhir Yadav, Virender Kumar, Timothy J. Krupnik, Bjoern Ole Sander, Joshua Cobb, Katherine Nelson, Tri Setiyono, Ranjitha Puskur, Pauline Chivenge, Martin Gummert

Faculty Publications

Climate change will continue to have a largely detrimental impact on the agricultural sector worldwide because of predicted rising temperatures, variable rainfall, and an increase in extreme weather events. Reduced crop yields will lead to higher food prices and increased hardship for low income populations, especially in urban areas. Action on climate change is one of the Sustainable Development Goals (SDG 13) and is linked to the Paris Climate Agreement. The research challenge posed by climate change is so complex that a trans-disciplinary response is required, one that brings together researchers, practitioners, and policy-makers in networks where the lines between …

Minor Preoccupations, Major Endeavors: The Community Of Poets And Painters, Adelaide M. Russo

Faculty Publications

In Au fond des images (2003), Jean-Luc Nancy introduces concepts about the image, pertinent to understanding the minor genre of poets’ writings on painting. Nancy begins by stating that the image is sacred, clarifying that the sacred should not be confused with the religious, which is based on rituals. The sacred signifies that which is separated, excluded, distanced. The image’s attraction is derived from this, from its untouchable nature. Because of its separation from the viewer, the image inspires a desire for intimacy, and draws the spectator to it. Poets’ texts on painting constitute minor forms: prefaces to catalogs, criticism, …

Evaluation Of Ultraviolet (Uv-C) Light Treatment For Microbial Inactivation In Agricultural Waters With Different Levels Of Turbidity, Achyut Adhikari, Katheryn J. Parraga Estrada, Vijay S. Chhetri, Marlene Janes, Kathryn Fontenot, John C. Beaulieu

Faculty Publications

Produce growers using surface or well water to irrigate their crops may require an appropriate water treatment system in place to meet the water quality standard imposed by FSMA Produce Safety Rule. This study evaluated the potential of using ultraviolet (UV-C) treatment in reducing the microbial population in agricultural water. Waters with turbidity levels ranging from 10.93 to 23.32 Nephelometric Turbidity Units (NTU) were prepared by mixing pond water and well water. The waters were inoculated with a cocktail of generic Escherichia coli (ATCC 23716, 25922, and 11775) and then treated with UV-C light (20–60 mJ/cm2). All tested doses of …

Plumage Patterns: Ecological Functions, Evolutionary Origins, And Advances In Quantification, Nicholas A. Mason, Rauri C.K. Bowie

Faculty Publications

Birds exhibit remarkable variation in plumage patterns, both within individual feathers and among plumage patches. Differences in the size, shape, and location of pigments and structural colors comprise important visual signals involved in mate choice, social signaling, camouflage, and many other functions. While ornithologists have studied plumage patterns for centuries, recent technological advances in digital image acquisition and processing have transformed pattern quantification methods, enabling comprehensive, detailed datasets of pattern phenotypes that were heretofore inaccessible. In this review, we synthesize recent and classic studies of plumage patterns at different evolutionary and organismal scales and discuss the various roles that plumage …

On The Usefulness Of Parental Lines Gwas For Predicting Low Heritability Traits In Tropical Maize Hybrids, Giovanni Galli, Filipe Couto Alves, Júlia Silva Morosini, Roberto Fritsche-Neto

Faculty Publications

Genome-wide association studies (GWAS) is one of the most popular methods of studying the genetic control of traits. This methodology has been intensely performed on inbred genotypes to identify causal variants. Nonetheless, the lack of covariance between the phenotype of inbred lines and their offspring in cross-pollinated species (such as maize) raises questions on the applicability of these findings in a hybrid breeding context. To address this topic, we incorporated previously reported parental lines GWAS information into the prediction of a low heritability trait in hybrids. This was done by marker-assisted selection based on significant markers identified in the lines …

Energetic And Environmental Constraints On The Community Structure Of Benthic Microbial Mats In Lake Fryxell, Antarctica, Megan L. Dillon, Ian Hawes, Anne D. Jungblut, Tyler J. Mackey, Jonathan A. Eisen, Peter T. Doran, Dawn Y. Sumner

Faculty Publications

© 2020 FEMS 2020. Ecological communities are regulated by the flow of energy through environments. Energy flow is typically limited by access to photosynthetically active radiation (PAR) and oxygen concentration (O2). The microbial mats growing on the bottom of Lake Fryxell, Antarctica, have well-defined environmental gradients in PAR and (O2). We analyzed the metagenomes of layers from these microbial mats to test the extent to which access to oxygen and light controls community structure. We found variation in the diversity and relative abundances of Archaea, Bacteria and Eukaryotes across three (O2) and PAR conditions: high (O2) and maximum PAR, variable …

Phylogenetic Afficity Of Genolopa (Digenea: Monorchiidae) With Descriptions Of Two New Species, Apryle J. Panyi, Stephen S. Curran, Robin M. Overstreet

Faculty Publications

The validity of Genolopa Linton, 1910 has been controversial because the observation of presently recognized critical diagnostic morphological features (spines in the genital atrium and a bipartite, anteriorly spined terminal organ) were omitted from the original diagnosis, and these features were not universally appreciated as important diagnostic features until 2008. Modern taxonomists have been further challenged by inappropriate fixation techniques that have resulted in various interpretations of morphological features. Consequently, named species in the genus have fluctuated among other monorchiid genera depending on various interpretations by taxonomists, and a modern consensus on classifying these species is lacking. This study …

Production Of The Polysaccharide Curdlan By Agrobacterium Species On Processing Coproducts And Plant Lignocellulosic Hydrolysates, Thomas P. West

Faculty Publications

This review examines the production of the biopolymer curdlan, synthesized by Agrobacterium species(sp.),on processing coproducts and plant ligno cellulosichydrolysates. Curdlanis a-(1 3)-D-glucan that has various food, non-food and biomedical applications. A number of carbon sources support bacterial curdlan production upon depletion of nitrogen in the culture medium. The influence of culture medium pH is critical to the synthesis of curdlan. The biosynthesis of the-(1 3)-D-glucan is likely controlled by a regulatory protein that controls the genes involved in the bacterial production of curdlan. Curdlan overproducer mutant strains have been isolated from Agrobacterium sp. ATCC 31749 and ATCC 31750 by chemical …

Mimicry As Movement Analysis, Rosa Abrahams

Faculty Publications

The analysis of movement to music often stems from examinations of video-recorded events. This allows the analyst an opportunity to re-watch, pause, and slow down the movements of their participants, and to produce descriptive notation that appears alongside a score (e.g., Roeder and Tenzer 2012). Unlike prescriptive forms of dance notation (e.g., Laban 1928), such transcriptions of movement often illuminate metrical connections between music and movement. However, when video-recording is not permissible, other methods of movement analysis must be developed. This paper pilots a new technique for rigorous analysis of the interaction between movement and music, which may be used …

An Artificial Habitat Increases The Reproductive Fitness Of A Range-Shifting Species Within A Newly Colonized Ecosystem, Zachary J. Cannizzo, Susan Q. Lang, Bryan Benitez-Nelson, Blaine D. Griffen

Faculty Publications

When a range-shifting species colonizes an ecosystem it has not previously inhabited, it may experience suboptimal conditions that challenge its continued persistence and expansion. Some impacts may be partially mitigated by artificial habitat analogues: artificial habitats that more closely resemble a species' historic ecosystem than the surrounding habitat. If conditions provided by such habitats increase reproductive success, they could be vital to the expansion and persistence of range-shifting species. We investigated the reproduction of the mangrove tree crab Aratus pisonii in its historic mangrove habitat, the suboptimal colonized salt marsh ecosystem, and on docks within the marsh, an artificial mangrove …

Influence Of Neighboring Clonal-Colonies On Aflatoxin Production By Aspergillus Flavus, Rebecca R. Sweany, Kenneth E. Damann

Faculty Publications

Aspergillus flavus is an ascomycete fungus that infects and contaminates corn, peanuts, cottonseed, and treenuts with acutely toxic and carcinogenic aflatoxins. The ecological function of aflatoxin production is not well understood; though not phytotoxic, aflatoxin may be involved in resisting oxidative stress responses from infection or drought stress in plants. Observation of aflatoxin stimulation in 48-well plates in response to increasing inoculated wells sparked an investigation to determine if A. flavus volatiles influence aflatoxin production in neighboring colonies. Experiments controlling several culture conditions demonstrated a stimulation of aflatoxin production with increased well occupancy independent of pH buffer, moisture, or isolate. …

Nutrition Intervention Using Behavioral Change Communication Without Additional Material Inputs Increased Expenditures On Key Food Groups In Bangladesh, Andrea M. Warren, Edward A. Frongillo, Phuong H. Nguyen, Purnima Menon

Faculty Publications

Background

Behavioral change communication (BCC) promotes skills and knowledge to improve infant and young child feeding, but without additional material inputs, recipients must develop strategies to translate knowledge into action. Using data from the Alive & Thrive initiative in Bangladesh (2010–2014), we aimed to test whether households receiving the intensive intervention (opposed to the nonintensive intervention) increased expenditures on key foods for mothers and children (e.g., foods that were promoted by the intervention and also changed in maternal and child diets).

Methods

The intensive intervention provided interpersonal counseling, community mobilization, and mass media campaigns to promote breastfeeding and complementary feeding. …

A Role For Oncostatin M In The Impairment Of Glucose Homeostasis In Obesity, Irene Piquer-Garcia, Laura Campderros, Siri D. Taxerås, Aleix Gavaldà-Navarro, Rosario Pardo, María Vila, Silvia Pellitero, Eva Martínez, Jordi Tarascó, Pau Moreno, Joan Villarroya, Rubén Cereijo, Lorena González, Marjorie Reyes, Silvia Rodriguez-Fernández, Marta Vives-Pi, Carles Lerin, Carrie M. Elks, Jacqueline M. Stephens, Manel Puig-Domingo, Francesc Villarroya, Josep A. Villena, David Sánchez-Infantes

Faculty Publications

© 2019 Endocrine Society 2019. Context: Oncostatin M (OSM) plays a key role in inflammation, but its regulation and function during obesity is not fully understood. Objective: The aim of this study was to evaluate the relationship of OSM with the inflammatory state that leads to impaired glucose homeostasis in obesity. We also assessed whether OSM immunoneutralization could revert metabolic disturbances caused by a high-fat diet (HFD) in mice. Design: 28 patients with severe obesity were included and stratified into two groups: (1) glucose levels /dL and (2) glucose levels >100 mg/dL. White adipose tissue was obtained to examine OSM …

Thermal Degradation Of Azobenzene Dyes, Thao L. Nguyen, Mahmoud A. Saleh

Faculty Publications

Ten azobenzene dyes were tested for their thermal degradation products from ambient temperature to 800 °C using a thermogravimetric technique. Degradation products were analyzed at each 100 °C increment using gas chromatography-mass spectrometry. Products were identified based on their mass spectral data and their retention times. Thermal degradation from all dyes resulted in loss of the azo group as nitrogen gas and aromatic free radicals. Electron withdrawing groups enhance the dissociation of the phenyl nitrogen bond at the benzene moiety carrying the electron withdrawing group. On the other hand, electron donating groups inhibited the dissociation of the phenyl-N bond of …

Methanol Leaf Extract Of Momordica Charantia Protects Alloxan-Induced Hepatopathy Through Modulation Of Caspase-9 And Interleukin-1Β Signaling Pathways In Rats, Sunday Oluwaseun Ofuegbe, Ademola Adetokunbo Oyagbemi, Temidayo Olutayo Omobowale, Aduragbenro Deborah Adedapo, Abiodun Emmanuel Ayodele, Momoh Audu Yakubu, Oluwafemi O. Oguntibeju, Adeolu Alex Adedapo

Faculty Publications

Background and Aim: Momordica charantia is a highly valued plant, widely distributed in the tropical and subtropical regions. The plant is reported to have a wide range of medicinal uses. This study was designed to explore the ameliorative potential of M. charantia methanol leaf extract in alloxan-induced diabetic animal model with a particular focus on the liver. Materials and Methods: Hepatoprotective effect of methanol leaf extract of M. charantia was assessed in alloxan-induced toxicity in 50 rats divided into five groups (A-E) (n=10). Group A normal control, Group B was toxicant group, and Group C animals received glibenclamide treatment while …

Effect Of Cocoa Powder On Hypertension And Antioxidant Status In Uninephrectomized Hypertensive Rats, Olayinka Christianah Jayeola, Ademola Adetokunbo Oyagbemi, Omolara Ibiwunmi Okunlola, Olayiwola Olubamiwa, Temidayo Olutayo Omobowale, Temitayo Olabisi Ajibade, Foluso Bolawaye Bolaji-Alabi, Blessing Seun Ogunpolu, Olufunke Olubunmi Falayi, Adebowale Benard Saba, Adeolu Alex Adedapo, Momoh Audu Yakubu, Afolabi Oluwadun, Oluwafemi Omoniyi Oguntibeju

Faculty Publications

Background and Aim: High salt diet and uninephrectomy are associated with high blood pressure with attendant cardiovascular disease conditions such as hypertension, renal damage, myocardial infarction, and stroke. The aim of this study was to investigate the beneficial effects of consumption of cocoa and cocoa-containing products in the management of high blood pressure in uninephrectomized hypertensive rats. Materials and Methods: The effect of cocoa powder on blood pressure, markers of inflammation, oxidative stress, and histopathology were investigated in uninephrectomized animals fed with cocoa feed alone or in combination with a high salt diet. Male rats were randomly divided into five …

Current Trends In The Pharmacotherapy Of Cataracts, Segewkal H. Heruye, Leonce N.Maffofou Nkenyi, Neetu U. Singh, Dariush Yalzadeh, Kalu K. Ngele, Ya Fatou Njie-Mbye, Sunny E. Ohia, Catherine A. Opere

Faculty Publications

Cataracts, one of the leading causes of preventable blindness worldwide, refers to lens degradation that is characterized by clouding, with consequent blurry vision. As life expectancies improve, the number of people affected with cataracts is predicted to increase worldwide, especially in low-income nations with limited access to surgery. Although cataract surgery is considered safe, it is associated with some complications such as retinal detachment, warranting a search for cheap, pharmacological alternatives to the management of this ocular disease. The lens is richly endowed with a complex system of non-enzymatic and enzymatic antioxidants which scavenge reactive oxygen species to preserve lens …

Interpretability Of Api Call Topic Models: An Exploratory Study, Puntitra Glendowne, Dae Glendowne

Faculty Publications

Topic modeling is an unsupervised method for discovering semantically coherent combinations of words, called topics, in unstructured text. However, the human interpretability of topics discovered from non-natural language corpora, specifically Windows API call logs, is unknown. Our objective is to explore the coherence of topics and their ability to represent the themes of API calls from malware analysts’ perspective. Three Latent Dirichlet Allocation (LDA) models were fit to a collection of dynamic API call logs. Topics, or behavioral themes, were manually evaluated by malware analysts. The results were compared to existing automated quality measures. Participants were able to accurately determine …

Simulating Medical Isolation: Communicatively Managing Patient And Medical Team Safety, Elizabeth Spradley, R. Tyler Spradley

Faculty Publications

Reducing hospital acquired or associated infections (HAIs) is a national public health priority. HAIs pose risks to patients, visitors, and medical personnel. To better understand how to communicatively manage safety in medical isolation, data was collected with nursing students simulating medical isolation in a high-fidelity simulation with a medical mannequin with C. difficile. Observations of nursing students and faculty revealed four distinct communication practices: social support, patient education, humor, and storytelling. Conclusions include recommendations to intentionally design these communication practices into high-fidelity medial isolation simulations and scale up these communication practices in routines of safety.

Light Emitting Diode (Led) Color And Broiler Growth: Effect Of Supplementing Blue/Green Led To White Led Light On Broiler Growth, Stress, And Welfare, Jill R. Nelson, Joey L. Bray, Juliette Delabbio, Gregory S. Archer

Faculty Publications

Light emitting diode (LED) lighting provides an affordable lighting option for use in commercial poultry production. However, more information is needed to understand the effects of LED color on broiler welfare and growth. Five consecutive flocks (1 in summer, 1 in fall, 2 in winter, and 1 in spring) of straight run Ross 708 × Ross 708 broilers were reared in commercial type barns for 45 D. For white only (WO) treatment, birds were reared under white LED only (Agrishift MLB). For white supplemented (WS) treatment, birds were reared under white LED (Agrishift MLB) in the center aisle, with supplemental …