Digital Commons Network^™

Virtual Motion Camouflage Based Nonlinear Constrained Optimal Trajectory Design Method, Gareth Basset

Electronic Theses and Dissertations

Nonlinear constrained optimal trajectory control is an important and fundamental area of research that continues to advance in numerous fields. Many attempts have been made to present new methods that can solve for optimal trajectories more efficiently or to improve the overall performance of existing techniques. This research presents a recently developed bio-inspired method called the Virtual Motion Camouflage (VMC) method that offers a means of quickly finding, within a defined but varying search space, the optimal trajectory that is equal or close to the optimal solution. The research starts with the polynomial-based VMC method, which works within a search …

Processing, Characterization And Performance Of Carbon Nanopaper Based Multifunctional Nanocomposites, Fei Liang

Electronic Theses and Dissertations

Carbon nanofibers (CNFs) used as nano-scale reinforcement have been extensively studied since they are capable of improving the physical and mechanical properties of conventional fiber reinforced polymer composites. However, the properties of CNFs are far away from being fully utilized in the composites due to processing challenges including the dispersion of CNFs and the viscosity increase of polymer matrix. To overcome these issues, a unique approach was developed by making carbon nanopaper sheet through the filtration of well-dispersed carbon nanofibers under controlled processing conditions, and integrating carbon nanopaper sheets into composite laminates using autoclave process and resin transfer molding (RTM). …

The Self-Described Experience Of Coping And Adaptation Associated With Workplace Stress Of Registered Nurses In The Acute Care Setting In Florida: An Ethnographic Study, Joyce Burr

Electronic Theses and Dissertations

Little is known about how nurses learn and use coping and adaptation skills in the workplace. Quantitative studies have identified the factors, nature, and outcomes of nursing stress. However, qualitative studies describing the human experience associated with workplace stress are lacking. The phenomenon of interest for this study using focused ethnographic method is the self-described experience of coping and adaptation associated with workplace stress of registered nurses working 12-hour shifts employed in acute care hospital facilities in east central and central Florida. Three aspects of the phenomena were examined: the self-described experiences of stress, the manner in which coping skills …

Understanding The Role Of Defects In The Radiation Response Of Nanoceria, Amit Kumar

Electronic Theses and Dissertations

Nanoscale cerium oxide (nanoceria) have shown to possess redox active property , and has been widely studied for potential use in catalysis, chemical-mechanical planarization, biomedical and solid oxide fuel cell (SOFC), etc. The redox state of nanoceria can be tuned by controlling the defects within the lattice and thus its physical and chemical properties. Perfect ceria lattice has fluorite structure and the research in last decade has shown that oxide and mixed oxide systems with pyrochlore and fluorite have better structural stability under high energy radiation. However, the current literature shows a limited number of studies on the effect of …

A Blue Flower: The Development Of A Personal Documentary, Nils Taranger

Electronic Theses and Dissertations

A Blue Flower is a feature-length documentary film by Nils Taranger, made as part of the requirements for earning a Master of Fine Arts in Entrepreneurial Digital Cinema from the University of Central Florida. The film focuses on the director’s journey to find healing, both physically and emotionally. Following the guidelines of UCF’s program, Nils produced the film on a microbudget (under $50,000) level. The majority of filming took place in Florida with only a one or two person crew. This thesis is a record of the film’s progression from development to picture lock, in preparation for distribution

The Extension Of Imperial Authority Under Diocletian And The Tetrarchy, 285-305ce, Joshua Petitt

Electronic Theses and Dissertations

Despite a vast amount of research on Late Antiquity, little attention has been paid to certain figures that prove to be influential during this time. The focus of historians on Constantine I, the first Roman Emperor to allegedly convert to Christianity, has often come at the cost of ignoring Constantine's predecessor, Diocletian, sometimes known as the "Second Father of the Roman Empire". The success of Constantine's empire has often been attributed to the work and reforms of Diocletian, but there have been very few studies of the man beyond simple biography. This work will attempt to view three of Diocletian's …

Design, Synthesis, And Biological Evaluation Of Novel Polyamine Transport System Probes And Their Application To Human Cancers, Aaron Muth

Electronic Theses and Dissertations

The mammalian polyamine transport system (PTS) has been of interest due to its roles in cancer and maintaining cellular homeostasis. Polyamines are essential growth factors which are tightly controlled via a balance of biosynthesis, metabolism, import, and export. This work focused on the development and biological testing of polyamine transport probes to help understand the molecular requirements of the PTS. This was mediated through the use of a CHO (PTS active) and CHO-MG* (PTS deficient) screen, where compounds demonstrating high toxicity in CHO and low toxicity in CHO-MG* were considered PTS selective. The first chapter focused on the development of …

Use Of An Activated Magnesium/Cosolvent System For The Desorption And Degradation Of Polycyclic Aromatic Hydrocarbons And Their Oxygenated Derivatives In Contaminated Soils, Marc Elie

Electronic Theses and Dissertations

The contamination of soils, with polycyclic aromatic hydrocarbons (PAHs), remains a widespread environmental concern. In the past two decades, many physical, chemical and biological methods have been developed and evaluated for the degradation of PAHs. However, due to their low aqueous solubility, high sorption affinity, hydrophobicity and recalcitrance, the environmental remediation of PAHs in soil continues to be economically challenging. In addition to PAH contamination, the presence of oxygenated derivatives of PAHs (OPAHs), in soils, has increasingly become a concern due to their greater toxic properties compared to parent PAH compounds. To date, no investigations on OPAH-remediation methods have been …

The Sacrament Of Violence: Myth And War In C.S. Lewis's Ransom Trilogy, Tanya Engelhardt

Electronic Theses and Dissertations

My primary aim for this study is to illuminate the Ransom trilogy's inherent psychological and spiritual themes, as well as demonstrate how these themes clarify Lewis's philosophical and political goals for the text. Specifically, by investigating Lewis's mythic imagery and suffering motifs in light of psychoanalytic and theological literary criticisms, I elucidate the reasoning behind Lewis's unique—and at times, horrific—portrayal of fear, violence, and death. I also investigate how Lewis integrates his theology with the horrors of personal and intrapersonal suffering, as well as how he utilizes imagination and myth to explicate the practical (or political) implications of his theodicy. …

The Relationship Between Caregiver Intimate Partner Violence, Posttraumatic Stress, Child Cognitive Self-Development, And Treatment Attrition Among Child Sexual Abuse Victims., Leigh De Delorenzi

Electronic Theses and Dissertations

Child sexual abuse (CSA) is a worldwide problem, with two-thirds of all cases going unreported. A wealth of research over the last 30 years demonstrates the negative emotional, cognitive, physical, spiritual, academic, and social effects of CSA. As a result, researchers and mental health professionals frequently attempt to measure the efficacy of treatment modalities in order to assess which treatments lead to better outcomes. However, in order to effectively study treatment outcomes, researchers must be able to track the status of child functioning and symptomology before, during, and after treatment. Because high levels of treatment attrition exist among CSA victims, …

Association Of Ring-Necked Pheasants And Conservation Reserve Program-Grasslands During The Brood-Rearing Season In Eastern South Dakota, Joshua J. White

Electronic Theses and Dissertations

Grassland established through the Conservation Reserve Program (CRP) has provided critical habitat for many wildlife species. Recent declines in CRP-grassland acreage attributed to changes in federal enrollment policy, increased biofuels production, and commodity prices may have negative consequences on wildlife populations. Conservation Reserve Program habitats have increased availability of quality nesting and over-winter cover for pheasants (Phasianus colchicus) in regions where large-scale conversions of native grasslands to cropland have occurred. The purpose of this study was to quantify the effect of CRP-grasslands on pheasants across a large geographic region. Primary objectives of the study were to determine presence/absence of pheasants …

Phytochemical Studies On The Medicinal Plant Sutherlandia Frutescens, Xiang Fu

Electronic Theses and Dissertations

Sutherlandia frutescens (L.) R. Br (Fabaceae) is a multipurpose medicinal plant with diverse biological activities, and has been widely used for the treatment of cancer, AIDS, diabetes, and infectious diseases in southern Africa. The primary goal of this study was to investigate the chemical constituents of S. frutescens and develop an analytical method to analyze this plant and the dietary supplements derived from this plant. The dissertation is composed of six chapters. Chapter 1 introduces the general background of S. frutescens, including traditional uses and chemical and biological studies on the plant. Chapter 2 describes the phytochemical studies that have …

Language As Microaggression: The New Lexicon Of American Racism, Juan Thurmond

Electronic Theses and Dissertations

There are countless occasions where marginalized groups bear witness to language-based discriminatory practices. Language, as defined here, is a species of symbolism. After reviewing the sociological literature, the term "microaggressions" appears to best describe the phenomena in its everyday occurrences. Microaggressions are "the brief and commonplace daily verbal, behavioral, and environmental indignities, whether intentional or unintentional, that communicate hostile, derogatory, or negative racial, gender, sexual-orientation, and religious slights and insults to the target person or group" (Sue, Capodilupo, et al., 2007; Sue, 2010). Sue classifies microaggressions into three forms: microassaults, microinsults, microinvalidations. The purpose of the project was tri-fold. By …

Antimicrobial Activity, Cytotoxicity And Phytochemical Analyses Of Rhus Aromatica, Rhus Glabra And Sanguinaria Canadensis Native To South Dakota, Gitanjali Nandakafle

Electronic Theses and Dissertations

A total of twenty five South Dakota native medicinal plants were screened against enterotoxigenic Escherichia coli using a disk diffusion assay. Out of these 25 plants, three plants Rhus aromatica, Rhus glabra and Sanguinaria canadensis demonstrated the highest bacterial inhibition. The minimum inhibitory concentrations (MIC) of these plant extracts were determined using a bacterial enumeration assay. Alamar Blue in vitro cytotoxicity test showed that all extracts have some toxic effect to porcine intestinal epithelial cell lines. Phytochemical analysis of these plant extracts indicated the presence high concentration of flavonoids and condensed tannins in R. aromatica and that R. glabra contained …

Optimization And Development Of In Vitro Bioassays To Determine Structure-Activity Relationships For Cannabinoid Receptor 1 And Cannabinoid Receptor 2, Afeef Husni

Electronic Theses and Dissertations

Cannabis has been around for thousands of years and has been used recreationally, medicinally, and for fiber. Over 400 compounds have been isolated from Cannabis sativa with approximately 100 being cannabinoids. Of those 100 compounds, Δ9-THC has been determined as the primary constituent, which is also responsible for the psychoactivity associated with Cannabis. Along with Δ9-THC, cannabidiol has been studied in depth for its therapeutic effects. This has currently been the focus of many researchers since cannabidiol does not cause psychotropic effects.

Cannabinoid receptors belong to the large superfamily of G protein-coupled receptors (GPCRs). Approximately 30% of marketed drugs target …

Pharmaceutical Formulation Development Utilizing Hot Melt Extrusion And Other Techniques For Development Of Immediate And Controlled Release Dosage Forms, Noorullah Naqvi Mohammed

Electronic Theses and Dissertations

Hot melt extrusion (HME) was evaluated as a processing technology for the manufacture of immediate as well as controlled release formulations for oral delivery of two model compounds. For immediate release applications lower molecular weight grades of Hydroxypropyl cellulose polymers, EF and ELF, were utilized as carrier matrices to form solid solutions of a poorly soluble compound, Ketoprofen (KPR). Thermal characterization techniques were used to confirm thermal stability, miscibility and setting up processing conditions for extrusion. Extruded matrices were pelletized to be filled into pellets or further milled and compressed into tablets. Pellets exhibited a carrier dependent release with ELF …

Accelerating The Performance Of A Novel Meshless Method Based On Collocation With Radial Basis Functions By Employing A Graphical Processing Unit As A Parallel Coprocessor, Derek Owusu-Banson

Electronic Theses and Dissertations

In recent times, a variety of industries, applications and numerical methods including the meshless method have enjoyed a great deal of success by utilizing the graphical processing unit (GPU) as a parallel coprocessor. These benefits often include performance improvement over the previous implementations. Furthermore, applications running on graphics processors enjoy superior performance per dollar and performance per watt than implementations built exclusively on traditional central processing technologies. The GPU was originally designed for graphics acceleration but the modern GPU, known as the General Purpose Graphical Processing Unit (GPGPU) can be used for scientific and engineering calculations. The GPGPU consists of …

Effects Of Off-Label Prescribing On Patient Decision Making, Douglas Paul

Electronic Theses and Dissertations

Objectives: Despite the comuse of off-label prescribing in the US, no research has been conducted to understand the impact of off-label prescribing on patient decision making. This study sought to measure the impact on trust in physicians, intentions of involvement in the decision making, beliefs about the drug, and initial compliance intentions in elderly and nonelderly populations. Methods. This study was designed to assess the effects of off-label prescribing using a 2 × 2 × 2 design. Using an online panel, 830 consumers were surveyed, 409 elderly and 421 nonelderly, using 8 different scenarios based on disease criticality, off-label use …

Close Encounters, Martin Anthony Arnold

Electronic Theses and Dissertations

Abstract: The expressiveness of the human figure is the syntax and vocabulary that I use to explore the things that make us human. In coming to really know an individual, we not only gain insights into our own psychological make-up, but we may extrapolate our findings to the broader human condition. Although intimately concerned with highlighting the characteristics that make my subjects distinctive, I am equally determined to examine those traits underscoring our commonality, that bind us all into a human family. I look for fresh ways to pull back the curtain of privacy and allow viewers to intrude on …

Synthesis And Characterization Of Nickel Complexes With Relevance To Nickel Acireductone Dioxygenase And Nickel Superoxide Dismutase, Margo Nicole Montgomery

Electronic Theses and Dissertations

This research presents an investigation of synthetic model complexes with relevance to the active site of Ni(II) acireductone dioxygenase (Ni-ARD) and Ni(II) superoxide dismutase (Ni-SOD). Acireductone dioxygenases (ARDs) are a unique set of enzymes found in the methionine salvage pathway that catalyze the oxidation reaction of acireductone (1, 2-dihydroxy-3-oxo-5-(methylthio)pent-1-ene). These enzymes share a compolypeptide sequence but bind different metal ions, Ni2+ or Fe2+, at the active site. The Ni-ARD enzyme is responsible for the off pathway shunt in the pathway. Using the tridentate nitrogen donor ligands hydrotris(3,5-dimethyl-1-pyrazolyl)borate (Tp*) and the newly developed tris(1, 2-dimethyl-4-imadozyl)carbinol, (4-TICMe, Me) several reactions involving the …

Theoretical And Spectroscopic Studies Of Molecular Systems For Charge Transfer And Energy Storage And Transfer, Debra Scardino

Electronic Theses and Dissertations

Efficient charge transfer and energy storage and transfer have become increasingly important in many areas of research and development. This is especially true for the development of optoelectronic devices, molecular electronics, and solar voltaic cells. Characterization of the photophysical properties of new molecular systems for these applications has emerged as an important field of research. Many molecular building blocks have been developed and understanding the properties of these systems at a fundamental level is essential for their successful implementation. This dissertation focuses on experimental and theoretical studies of some of these newly-developed molecular systems. Oxygen substituted dihydrobenzvalene is studied theoretically …

The Cost Of Kinship: Southern Literary Families And The Capitalist Machine, Joshua Sean Lundy

Electronic Theses and Dissertations

The purpose of this thesis is to examine the thematic role of families and the familial in the literature of the Southern Renaissance. Whereas a number of scholars have come at this matter from a strictly cultural perspective, this analysis utilizes an economic framework. Following the example set by Karl Marx, Freidrich Engels, Gilles Deleuze, and Felix Guattari, I attempt to formulate an understanding of the southern family not as an independent and singular social organism, but, rather, as a mechanism for the distribution of capital, firmly embedded within modern capitalism's expansive network of production, consumption, and exchange. My argument …

Masculinity In Comparative Black Literatures, Latoya Renee Jefferson

Electronic Theses and Dissertations

This project examines the ways in which Black men in Africa and throughout the African Diaspora define themselves as gendered beings in their fiction and drama beginning with Richard Wright's publication of Native Son in 1940 to Mariama Ba's So Long a Letter published 1980. Black men created a transnational dialectic concerning their masculinity which involved the creation and criticism of several types of masculinity. In Chapters 1 and 2, I discuss the theoretical and the historical framework for this project. In Chapter 3, I discuss the first type of Black masculinity which was based in opposition to Euro-American stereotypes …

Functional Studies Of Novel Bioactives From Complex Host-Microbiomes As Drug Leads For Cancer, Infectious Disease, Depression And Pain, John Jason Bowling

Electronic Theses and Dissertations

The drug discovery process has become increasingly complex in comparison to early efforts particularly those involving diseases or conditions that affect large numbers of the human population. It is difficult to point directly to one factor leading evolution of the process but the definition of a mechanism of pharmacological action for a drug lead has noticeably become a higher priority. This evolution has helped diminish the stigma of natural products and compound supply issues. The issue of compound supply has also been addressed to some extent with the emergence of recombinant technologies and new synthetic methodology. With approximately 60 years …

On The Nature Of Weak Intermolecular Forces: A First Principles Approach To Hydrogen Bonding And Pi-Type Interactions, Kari Lorene Copeland

Electronic Theses and Dissertations

Computational quantum chemistry is a branch of chemistry that is based on quantum mechanics. In this field, chemical phenomena is represented in mathematical form and computers are used to provide numerical solutions to rigorous mathematical equations. Through this medium, the properties of atoms and molecules are calculated with high accuracy. Chapter 1 opens with a general discussion of science, the development of atomic theory and computational chemistry. Electronic structure theory is more extensively reviein Chapter 2. Hydrogen bonding and dispersion forces are defined in Chapter 3, and the procedures used to computationally study these type interactions are considered. Chapter 4 …

Between God And Man: Community's Place In Virtue, Practical Reason, And Transcendent Good, Jordan Herz Davis

Electronic Theses and Dissertations

Talbot Brewer's Retrieval of Ethics and Robert Adams's Finite and Infinite Goods present distinct theories in ethics and metaethics. Brewer begins with the fundamental ethical perspective of the practical deliberator who experiences his practical deliberations as a continuous, unified, and constantly revised activity which begins with inchoate intimations of goodness and proceeds better or worse to understand and pursue the goodness which pervades his evaluative outlook. From this Brewer aims to account for how we achieve excellence in practical deliberation and arrive at a more tenable and self-consistent evaluative outlook which informs our ethical deliberations. Alternately, Adams begins in the …

Synthesis And Evaluation Of Naturally Occuring Halogenated Bipyrroles In A Relevant Marine Species, Fundulus Heteroclitus, Kimberly Sheree Foster

Electronic Theses and Dissertations

Halogenated dimethyl-2-2'-bipyrroles (HDBPs) have recently been discovered in seabird eggs and have been shown to bioaccumulate in trophic organisms. HDBPs are suspected to be biogenic in nature, derived from evidence of marine natural products that are persistent in the environment and widespread in the Pacific and Atlantic Ocean. The HDBPs exhibit chlorinated and brominated substitution patterns that closely resemble anthropogenic pollutants like the polychlorinated biphenyls (PCBs), polybrominated biphenyls (PBBs), and polybrominated diphenyl ethers (PBDEs). Environmental health concerns exists regarding these naturally occurring HDBPs because several of these analogs were shown to induce the cytochrome P4501A (CYP1A) gene through activation of …

The Effects Of A Multi-Component Wellness Program On Employee Biometrics, Jennifer Erin Patrick

Electronic Theses and Dissertations

Corporate wellness initiatives are gaining momentum as a critical indicator of business performance. Metabolic Syndrome is commonly used within corporations to assess the health of their employees and estimate potential healthcare costs. Using five risk factors (blood pressure, high density lipoprotein (HDL-C), triglycerides (TG), fasting blood glucose, and waist circumference) individuals with three or more risk factors are classified as having Metabolic Syndrome. Voluntary pre and post health screenings were conducted at a rural manufacturing plant. A multi-component wellness program was conducted over six months to determine if the program would have significant beneficial effects on employee biometrics and Metabolic …

Staging Sodomy: Deviance And Devotion On The Early English Stage, Bobby Ellis Pelts

Electronic Theses and Dissertations

This thesis is an examination of the multivalent category of sodomy in late medieval works of and about biblical drama: A Tretise of Miraclis Pleyinge, the York Joseph's Trouble About Mary and the N-Town Passion plays. Because the Tretise of Miraclis Pleyinge invokes charges of sodomy in its attack on biblical drama, this work argues that the medieval stage is particularly hospitable to exploring the queer moments of Christian theology. Focusing on the sodomitic relationships of Christ's life as they are revealed in York's Joseph's Trouble and the N-Town Passion sequences, this thesis argues that these plays problematize Christ's legendary …

A Fractal Analysis Of The Detection Of Glucose Molecules On Biosensor Surfaces, Lokesh Taneja

Electronic Theses and Dissertations

A fractal analysis for the binding and dissociation of glucose molecules to different biosensor surfaces is presented. The sensors contain immobilized glucose oxidase enzymes that have an affinity for the glucose molecules in solution. Data for different modified biosensors is modeled and analyzed, and a single, dual or triple-fractal analysis is applied where adequate. The binding and dissociation kinetics coefficient where applicable are calculated for each of models along with the fractal dimensions. When both binding and dissociation phases are present, the affinity, K of the receptor to the glucose molecule is calculated and its variation with the fractal dimension …