Digital Commons Network^™

Identification Of A Treatment-Resistant, Ketamine-Sensitive Genetic Line In The Chick Anxiety-Depression Model, Stephen Walter White

Electronic Theses and Dissertations

Approximately 60% of Major Depressive Disorder (MDD) patients do not respond to FDA-approved antidepressants. Introducing effective pharmacotherapies for this treatment-resistant population is hindered by the lack of pre-clinical screening assays that accurately model the clinical features of TRD. The purpose of this research was to screen representatives of different classes FDA-approved antidepressants and one novel antidepressant in two genetic lines of domestic fowl chicks that have previously been identified as stress-vulnerable and stress-resilient in the chick anxiety depression model. Separate groups of socially raised Black Australorp (stress-vulnerable) and Production Red (stress-resilient) chicks were administered the tricyclic antidepressant imipramine (0-20 mg/kg), …

Migratory Connectivity And Carry-Over Effects In Northwest Atlantic Loggerhead Turtles (Caretta Caretta, L.), Simona Ceriani

Electronic Theses and Dissertations

Migration is a widespread and complex phenomenon in nature that has fascinated humans for centuries. Connectivity among populations influences their demographics, genetic structure and response to environmental change. Here, I used the loggerhead turtle (Caretta caretta, L.) as a study organism to address questions related to migratory connectivity and carry-over effects using satellite telemetry, stable isotope analysis and GIS interpolation methods. Telemetry identified foraging areas previously overlooked for loggerheads nesting in Florida. Next, I validated and evaluated the efficacy of intrinsic markers as a complementary and low cost tool to assign loggerhead foraging regions in the Northwest Atlantic Ocean (NWA), …

Tractors And Genres: Knowledge-Making And Identity Formation In An Agricultural Community, Marcy Galbreath

Electronic Theses and Dissertations

This research examines the history of a small Florida agricultural community over the course of the twentieth century from a rhetorical perspective in order to understand the technological and communicative transitions that governed the development of American agricultural production. By examining archival and oral histories, this research will add to our understandings of how written and oral communications temper the relationships and social situations of an agricultural community, including the knowledge-making and technological adaptation resulting from communications within the community and with outside institutions and entities. Agricultural villages are not isolated entities, but rather sites of multiple rhetorical situations, and …

Ipads For Students With Asd: Comparing Delivery Modes For Visual Activity Schedules, Jillian Gourwitz

Electronic Theses and Dissertations

Visual Activity Schedules (VAS) are tools that present an abstract concept, such as time, in a more concrete and manageable form. VAS allow students to anticipate upcoming events and activities, develop an understanding of time, and facilitate the ability to predict change. Prior investigations have used VAS to increase on-task behavior while enhancing the student's ability to independently make transitions from one activity to another and are particularly appropriate as they capitalize on the visual strengths exhibited by many students with autism. Mobile devices such as the iPad are becoming a tool for teaching students with disabilities, and research is …

Evaluation Of The Three-Dimensional Patterns And Ecological Impacts Of The Invasive Old World Climbing Fern (Lygodium Microphyllum), Alexis Maldonado

Electronic Theses and Dissertations

Invasion by non-native species has had significant ecological and economic impacts on a global scale. In the state of Florida, Old World climbing fern (Lygodium microphyllum) is an invasive plant listed by FLEPPC as a category one invader with significant ecological impacts that threaten native plant diversity. This species relies on existing vegetative structures for support to climb into the forest canopy and forms dense mats that cover tree crowns. This subsequently affects the resources available to other species present. Quantifying the structural changes due to the presence of this species has proved logistically difficult, especially on a large spatial …

The Fate Of Nitrogen And Phosphorus From A Simulated Highway Cross-Section, Zuzanna Wasowska

Electronic Theses and Dissertations

Nutrient pollution as a result of excessive fertilizer application is of major concern for Florida's water resources. Excess fertilizer can be lost either via surface runoff or by leaching through the soil mass eventually reaching water bodies and leading to eutrophication. The focus of this study is to analyze the effect of low rainfall intensities and overland flow from an adjacent roadway surface on the loss of nutrients from two different fertilizers. This study focuses on the fate of the nitrogen and phosphorus present in fertilizers utilized by the Florida Department of Transportation for the stabilization of highway embankments. This …

Real Time Monitoring Of Cell-Nanoparticles Interaction And Tracking Internalization Process By Mechanical Probing Using Atomic Force Microscopy, Anh Ly

Electronic Theses and Dissertations

With extensive development of nanotechnology in last few years, scientists have discovered that nanoparticles (NPs) can be used as an efficient Drug Delivery System (DOS). In order to develop better NPs based drug delivery tool, it is imperative to understand the interaction between the NPs and the cell membrane. In our earlier studies, cerium oxide nanoparticles (CNPs) have been reported to have therapeutic properties, specifically against abnormalities associated with oxidative stress. Therefore, CNPs with different sizes and morphology were selected to understand the interaction with cell. We analyzed the mechanical property of human nasal septum tumor cells membranes using Atomic …

Identity Construction And Information Processing In A Coaching Relationship: The Effects Of Coach Behavior On Coachee Goal-Setting And Commitment, Christopher Coultas

Electronic Theses and Dissertations

Coaching (professional, business, executive, leadership) has been shown to be effective generally speaking, but questions remain regarding the explanatory mechanisms underlying coaching. I first propose a context-general model that unpacks the sociocognitive dynamics within coaching. The model explains the emergence of different types of coaching relationships, and how the nature of these relationships differentially determine coaching outcomes. Research and theory on social identity construction and information processing in dyads provides the foundation upon which I outline a model describing the process and dynamics of coaching identity emergence. Beyond this emergence, my proposed model states that the coachee's understanding of appropriate …

Plugging Up The Leaky Stem Pipeline With A Stereotype Threat Mentoring Intervention, Luiz Xavier

Electronic Theses and Dissertations

The present study compared the effectiveness of different mentoring programs at reducing feelings of stereotype threat experienced by women in science, technology, engineering, and math (STEM) fields. Stereotype threat refers to the extra pressure a person feels to disprove a negative stereotype that applies to him or her. Because stereotype threat has been found to undermine performance and interest in stereotyped domains, it may be a key factor contributing to female underrepresentation in STEM fields. Mentors and proteges were placed in either a stereotype threat reduction condition in which mentors and proteges were encouraged to participate in discussions designed to …

Determination Of The Expression Patterns Of The Nine Csp Genes In Escherichia Coli K-12 Mg1655 And The Growth Defects Associated With Deletion Of These Genes, Tiffany R Czapski

Electronic Theses and Dissertations

Cold-shock proteins (CSPs) are a family of small nucleic acid-binding proteins. In Escherichia coli K-12, there are 9 homologous csp genes named A-I. Aside from microarray studies, transcript levels from all nine csp genes have never been assayed using the same technique. The objectives of this study were to determine when these genes are expressed, if homologous pairs are expressed the same, how many are cold-shock inducible, and if there is a ranking of importance for these genes. To answer these questions, I determined csp mRNA expression patterns for all nine csp genes during normal growth at 37°C, and after …

The Genetics Of Conservation Translocations: A Comparison Of North American Golden Eagles (Aquila Chrysaetos Canadensis) And Bald Eagles (Haliaeetus Leucocephalus), Maria Wheeler

Electronic Theses and Dissertations

In the past half-century, two raptors with similar life histories, bald eagles (Haliaeetus leucocephalus) and golden eagles (Aquila chrysaetos canadensis) were the subjects of either broad-scale reintroduction or translocation projects in North America. These two different conservation approaches provided the framework for a retrospective natural experiment. The goal of my research was to determine the effects of these two conservation management approaches on the genetic population structure of each species. Methods included sequencing cyt b mtDNA and genotyping 10 microsatellite loci for contemporary and historic golden eagles and bald eagles. Contemporary samples were collected from captive and wild birds, and …

Identifying Influential Agents In Social Systems, Mahsa Maghami

Electronic Theses and Dissertations

This dissertation addresses the problem of influence maximization in social networks. In- fluence maximization is applicable to many types of real-world problems, including modeling contagion, technology adoption, and viral marketing. Here we examine an advertisement domain in which the overarching goal is to find the influential nodes in a social network, based on the network structure and the interactions, as targets of advertisement. The assumption is that advertisement budget limits prevent us from sending the advertisement to everybody in the network. Therefore, a wise selection of the people can be beneficial in increasing the product adoption. To model these social …

Integrated Remote Sensing And Forecasting Of Regional Terrestrial Precipitation With Global Nonlinear And Nonstationary Teleconnection Signals Using Wavelet Analysis, Lee Mullon

Electronic Theses and Dissertations

Global sea surface temperature (SST) anomalies have a demonstrable effect on terrestrial climate dynamics throughout the continental U.S. SST variations have been correlated with greenness (vegetation densities) and precipitation via ocean-atmospheric interactions known as climate teleconnections. Prior research has demonstrated that teleconnections can be used for climate prediction across a wide region at sub-continental scales. Yet these studies tend to have large uncertainties in estimates by utilizing simple linear analyses to examine chaotic teleconnection relationships. Still, non-stationary signals exist, making teleconnection identification difficult at the local scale. Part 1 of this research establishes short-term (10-year), linear and non-stationary teleconnection signals …

Arrangement Of Google Search Results And Imperial Ideology: Searching For Benghazi, Libya, Jacob Stewart

Electronic Theses and Dissertations

This project responds to an ongoing discussion in scholarship that identifies and analyzes the ideological functions of computer interfaces. In 1994, Cynthia Selfe and Richard Selfe claimed that interfaces are maps of cultural information and are therefore ideological (485). For Selfe and Selfe and other scholars, these interfaces carried a colonial ideology that resulted in Western dominance over other cultures. Since this early scholarship, our perspectives on interface have shifted with changing technology; interfaces can no longer be treated as having persistent and predictable characteristics like texts. I argue that interfaces are interactions among dynamic information that is constantly being …

The Best And Worst Of All That God And Man Can Do": Paternalistic Perceptions On The Intellectually Disabled At Florida's Sunland Institutions., Bethany Dickens

Electronic Theses and Dissertations

Historians have studied mental institutions in the mid-20th century; however, few have discussed them within the context of the period's paternalistic social movements and perceptions. Florida's Sunland program provides a lens for studying the parental role the institutions and general public took toward the intellectually disabled. Specifically, administrators saw residents of the Sunland Training Centers and Hospitals as perpetual children, trapped in an "eternal childhood." The institution was presented as a family unit, abiding by 1950s ideals of the companionate household. When the Sunlands proved generally unsuccessful, Florida's communities began to supplement their efforts. The social movements of the 1960s …

The Spatial Relationship Between Labor, Cultural Migration, And The Development Of Folk Music In The American South: A Digital Visualization Project, Robert Clarke

Electronic Theses and Dissertations

This Digital/Public History visualization thesis project explores how three factors-Atlantic migration patterns, demographics, and socioeconomic systems-influenced the development of folk music in the southern United States from the 18th century through the 20th century. A large body of written scholarship exists addressing plantation economies, the slave trade, and folk music. Digital technology, however, creates new opportunities for analyzing the geo-temporal aspects contained within the numerous archival resources such as census and migration records, field recordings, economic data, diaries, and other personal records. The written portion of the thesis addresses the historiography, research findings, and the process of creating the visualization …

Study Of The Formation And Control Of Disinfection By-Products Originating From A Surface Water Supply On The Volcanic Island Of Guam, Erica Laberge

Electronic Theses and Dissertations

Three oxidants have been evaluated for use as alternative chemical pretreatments for Fena Lake, a surface water that supplies the U.S. Navy's Public Water System (PWS) on the volcanic island of Guam. The study consisted of two investigative components. The first and primary component included a bench-scale evaluation to study the effects of different pre-oxidant chemicals on the formation of chlorinated disinfection by-products (DBPs). The second and ancillary component included a series of water treatment and distribution system management studies that analyzed DBP formation within the treatment plant and water distribution system. The goal of this research was to reduce …

An Unsupervised Consensus Control Chart Pattern Recognition Framework, Siavash Haghtalab

Electronic Theses and Dissertations

Early identification and detection of abnormal time series patterns is vital for a number of manufacturing. Slide shifts and alterations of time series patterns might be indicative of some anomaly in the production process, such as machinery malfunction. Usually due to the continuous flow of data monitoring of manufacturing processes requires automated Control Chart Pattern Recognition(CCPR) algorithms. The majority of CCPR literature consists of supervised classification algorithms. Less studies consider unsupervised versions of the problem. Despite the profound advantage of unsupervised methodology for less manual data labeling their use is limited due to the fact that their performance is not …

Automatic Detection Of Brain Functional Disorder Using Imaging Data, Soumyabrata Dey

Electronic Theses and Dissertations

Recently, Attention Deficit Hyperactive Disorder (ADHD) is getting a lot of attention mainly for two reasons. First, it is one of the most commonly found childhood behavioral disorders. Around 5-10% of the children all over the world are diagnosed with ADHD. Second, the root cause of the problem is still unknown and therefore no biological measure exists to diagnose ADHD. Instead, doctors need to diagnose it based on the clinical symptoms, such as inattention, impulsivity and hyperactivity, which are all subjective. Functional Magnetic Resonance Imaging (fMRI) data has become a popular tool to understand the functioning of the brain such …

Nano-Pipette As Nanoparticle Analyzer And Capillary Gated Ion Transistor, Yauheni Rudzevich

Electronic Theses and Dissertations

The ability to precisely count inorganic and organic nanoparticles and to measure their size distribution plays a major role in various applications such as drug delivery, nanoparticles counting, and many others. In this work I present a simple resistive pulse method that allows translocations, counting, and measuring the size and velocity distribution of silica nanoparticles and liposomes with diameters from 50 nm to 250 nm. This technique is based on the Coulter counter technique, but has nanometer size pores. It was found that ionic current drops when nanoparticles enter the nanopore of a pulled micropipette, producing a clear translocation signal. …

A Spatial Analysis Of Chachapoya Mortuary Practices At La Petaca, Chachapoyas, Peru, Lori Epstein

Electronic Theses and Dissertations

Diversity of Chachapoya mortuary practices is not well understood archaeologically, even though the region has received some attention for the monumental constructions and visually striking mortuary complexes located high on open cliff faces. This may be due to the difficult accessibility and often poor state of preservation consistent with many Chachapoya mortuary and occupation sites. This thesis reconstructs mortuary practices at La Petaca in the Chachapoyas region of Peru, applying paleodemographic and GIS methodological approaches to facilitate and improve the bioarchaeological study of commingled skeletal remains in an open, disturbed communal funerary context. Research focused on SUP CF-01, a natural …

Keren, Shelly Bradon

Electronic Theses and Dissertations

The intent of this thesis is to recognize the everyday victories of a child living with physical disabilities. This complicated subject matter has forced the exploration of a variety of media to successfully communicate the story; drawing, painting, china painting, altered books and sculpture have all become part of the process. At the age of 8 months the subject, Keren Hernandez, was diagnosed with Bilateral Closed- lip Schizencephaly, a rare disorder that inhibits development. Since the diagnosis seven years ago her family has struggled to overcome these challenges, committing to avail themselves to every resource possible. I began painting and …

Zinc Sulfide: Manganese Doped Quantum Rods For Detection Of Metal Ions And A Business Model For Future Sales, Andrew Teblum

Electronic Theses and Dissertations

Hexavalent chromium is an extremely carcinogenic chemical that has been widely produced in the United States. This has led to major waste contamination and pollution throughout the country. According to the Environmental Working Group Hexavalent chromium has been found in 89% of city tap water. Most people believe they are safe using regular home filter systems however that is not true. A more expensive ion exchange water treatment unit is required. Therefore to protect yourselves from this carcinogenic metal a reliable test is required. In this study we have developed a Zinc Sulfide Manganese doped Quantum Rod technology to detect …

Lactational Performance Of Dairy Cows Fed Yeast Derived Microbial Protein In Low And High Forage Diets, Angela Kristia Manthey

Electronic Theses and Dissertations

The objective of this study was to investigate the effect of substituting soybean meal products with yeast-derived microbial protein [(YMP) DEMP; Alltech Inc., Nicholasville, KY] in diets containing two forage concentrations. Sixteen Holstein cows (4 primiparous and 12 multiparous) were randomly assigned to a replicated 4 × 4 Latin square in a 2 × 2 factorial arrangement of treatments. Diets contained low (LF; 45% of diet DM) or high forage (HF; 65% of diet DM) and YMP at 0 (NYMP) or 2.25% (WYMP) of the diet. The forage mix consisted of 67% corn silage and 33% alfalfa hay (DM basis). …

The Development And Application Of A Larval Pallid Sturgeon (Scaphirhynchus Albus) Bioenergetics Model, Laura B. Heironimus

Electronic Theses and Dissertations

Pallid Sturgeon Scaphirhynchus albus are native fish of the Missouri and lower Mississippi River basins and currently listed as an endangered species under the Federal Endangered Species Act. As a result of anthropogenic alterations within the Missouri River, including dredging, channelization, and construction of large reservoirs, Pallid Sturgeon reproduction is reduced or eliminated throughout the species range. Due to a lack of wild progeny, little is known of the larval Pallid Sturgeon and their habitat or environmental requirements. To increase knowledge on the larval Pallid Sturgeon’s physiological requirements for growth and survival, the objective of this study was to develop …

Determining Impacts Of Mountain Lions On Bighorn Sheep And Other Prey Sources In The Black Hills, Joshua B. Smith

Electronic Theses and Dissertations

From 2009 to 2013, we assessed cougar (Puma concolor) feeding habits and bighorn sheep (Ovis canadensis) population dynamics in the Black Hills, South Dakota. We used Global Positioning System (GPS) telemetry to locate 1,506 cougar feeding events and found deer (Odocoileus spp.; 83%), primarily white-tailed deer (O. virginianus), dominated cougar diets. Overall ungulate kill rate averaged 0.79 ungulates/week (range = 0.13–1.75 ungulates/week), and was significantly higher (P < 0.001) in summer (xˉ = 0.92; SE = 0.06) than in winter (xˉ = 0.62; SE = 0.06). In contrast, biomass consumed was significantly higher (P = 0.033) in winter (xˉ = 8.23 kg/day; SE = 0.96) than in summer (xˉ = 5.45 kg/day; SE = 0.43), primarily as a result of increased scavenging (winter = 0.21 events/week; summer = 0.08 events/week), which represents the highest documented rate for cougar populations studied. We also documented a relatively high rate of chronic wasting disease- (CWD) infected elk in 2 cougar (1 male; 1 female) diets (64%; 95% CI = 50.3–78.3%) and speculate that CWD infection likely increased elk predation risk. Annual lamb survival was 0.02 (SE = 0.01) with pneumonia (36%) and predation (30%) the leading causes of mortality. We found pneumonia and predation were temporally heterogeneous with lambs most susceptible to predation during the first 2–3 weeks of life, while the greatest risk from pneumonia occurred from weeks 4–8. Annual ewe survival was 0.81 (SE = 0.04) with pneumonia (19%) and predation (19%) the leading causes of documented mortality; 48% were unknown. Additionally, we used vaginal implant transmitters (VITs) to assess capture efficiency and document parturition and neonate lamb bed site selection for bighorn sheep. We found successful VITs increased capture efficiency (95%) over unsuccessfully-vitted ewes (81%) and ewes not equipped with VITs (70%). Bighorn ewes selected for rugged terrain at both macro- and microhabitat scales, while at the macrohabitat scale ewes selected for areas that were close to perennial streams on south and west facing slopes and against anthropogenic disturbance. At the microhabitat scale, neonate lambs tended to select for greater cover and against north facing slopes.

Shifgrethor As The Deterministic Theme In Ursula K. Le Guin's The Left Hand Of Darkness, Amber Hanson

Electronic Theses and Dissertations

While Ursula K. Le Guin’s The Left Hand of Darkness has received much attention, scholars have largely overlooked one dynamic and integral device found in the novel, that of shifgrethor. This thesis offers an exposition of this LeGuinian device, by examining shifgrethor as theme within a Russian Formalism framework, by first establishing a working definition, and then by examining the device used within the novel to establish it as a theme. In the first chapter, I offer the reasons behind my interest in the novel and then move into providing an overview of previous research done on The Left Hand …

Evaluation And Application Of A New Shape-Sensitive Metric Useful For Characterizing Both Spectral Curves And Lidar Waveforms, Eric Ariel L. Salas

Electronic Theses and Dissertations

This dissertation seeks to investigate hyperspectral and waveform LiDAR datasets through a new analytical framework called Moment Distance method that uses a metric derived from the shape of the curve (spectral or waveform). In the case of hyperspectral data, the shape of the reflectance curve should unmask fine points of the spectra usually not considered by existing band-specific indices. To explore the advantages and shortcomings of this new approach, leaf and canopy hyperspectral reflectance samples were simulated using the physicallybased models PROSPECT (a leaf model) and SAIL (a canopy model). Sensitivity analysis was conducted with the goal of understanding the …

Solubility Enhancement And Precipitation Inhibition Of Poorly Water Soluble Compounds Utilizing Hot Melt Extrusion Technology, Jiannan Lu

Electronic Theses and Dissertations

Soluplus® (SOL), a graft amorphous copolymer, composed of polyethylene glycol, vinyl acetate and vinylcaprolactam in a ratio of 13: 30: 57, was utilized to prepare solid dispersions containing felodipine (FEL) or ketoconazole (KTZ) using hot-melt extrusion technology. The melting point depression approach was utilized to determine the miscibility and solubility of the model compounds within Soluplus® , of which felodipine demonstrated higher solubility when compared to ketoconazole (14% vs 4.3% w/w) at room temperature (298K). Moreover, the solubility parameters of FEL, KTZ and SOL were calculated as 21.76, 26.51 and 21.64, respectively.

Polarized light microscopy, Fourier transform infrared spectroscopy (FT-IR), …

The Effects Of Stress Hormones On Preferences For Acoustic Signals In Female Green Treefrogs (Hyla Cinerea) And Barking Treefrogs (Hyla Gratiosa), Anna Gabriell Davis

Electronic Theses and Dissertations

Ecological stressors (i.e., high predator density, low food availability) are often associated with increased variation in mate choice by females. The association between environmental stressors and variation in mate choice suggests that circulating stress hormones (i.e., glucocorticoids) may mediate such effects, but this idea remains largely unexplored. I examined how circulating glucocorticoids affect preferences for male advertisement calls in female green treefrogs, Hyla cinerea, and barking treefrogs, Hyla gratiosa. Specifically, I examined whether administration of corticosterone (CORT) decreases preferences for call rate and/or call duration - two acoustic features that are highly variable and characteristically under directional selection via mate …