Digital Commons Network^™

Analysis Of The Effects Of Formative Assessment In Promoting Transfer Of Learning In An Undergraduate General Microbiology Laboratory Course, Andrea Rediske

Electronic Theses and Dissertations

The undergraduate microbiology lab serves an important role in establishing a foundation of best practices in aseptic technique and infection control for pre-medical, pre-nursing, pre-pharmacy, or pre-allied health students. The high incidence of hospital-acquired infections (HAIs) in the US and evidence in the literature of less effective implementation of proper aseptic technique among apprentice doctors and nursing students suggests that more effective transfer of learning could improve implementation of these procedures in the clinical setting. The research described in this study aimed to assess learning transfer as it applied to aseptic techniques and infection control skills learned in the undergraduate …

Filtering Problems In Stochastic Tomography, Tyler Gomez

Electronic Theses and Dissertations

Distinguishing signal from noise has always been a major goal in probabilistic analysis of data. Such is no less the case in the field of medical imaging, where both the processes of photon emission and their rate of absorption by the body behave as random variables. We explore methods by which to extricate solid conclusions from noisy data involving an X-ray transform, long the mathematical mainstay of such tools as computed axial tomography (CAT scans). Working on the assumption of having some prior probabilities assigned to various states a body can be found in, we introduce and make rigorous an …

Examining The Role Of Cardiovascular And Cognitive Fitness In Goal-Directed Aiming Across The Lifespan, Michael Rupp

Electronic Theses and Dissertations

Older adults experience more difficulties completing goal directed movements than younger adults. The reasons for this have not been completely elucidated within the research literature; however, it is thought that age related movement differences are due to at least one of three possible reasons. The current study investigated the influence of these three hypotheses: (1) biomechanical changes (limbs, joints, or muscles), (2) sensory feedback processing ability, or (3) differences in overall movement strategy on movement kinematics. Additionally, physical activi-ty is known to improve both physical and cognitive functioning and staying cognitively active may also attenuate age-related declines in cognitive ability; …

Monitoring Crystal Structure Refinements Using Solid-State Nmr Chemical Shift Tensors, Keyton Kalakewich

Electronic Theses and Dissertations

Inclusion of lattice-fields in density functional theory (DFT) methods has enabled the accurate calculation of solid-state nuclear magnetic resonance (SSNMR) chemical shift tensors. Calculated 13C and 15N tensors (i.e. 3 principle values per nucleus) can be used to monitor crystal structure refinements and to select the correct structure from a large population of computationally generated candidates. In this dissertation, chapter 2 describes a methodology to improve established crystal structures from three different diffraction techniques involving geometric refinement monitored using SSNMR tensor values. The calculated 13C tensors for three relatively simple organic compounds (i.e. acetaminophen, naphthalene, and adenosine) are shown to …

Using Molecular Genetic And Demographic Tools To Improve Management Of Ex Situ Avian Populations, Gina Ferrie

Electronic Theses and Dissertations

Small populations, specifically those that are isolated from others, are more prone to extinction than larger inter-connected populations. The risks that these small isolated populations face include loss of genetic diversity due to founder effects and inbreeding due to population bottlenecks, as well as demographic uncertainty due to fluctuating fecundity and mortality rates and impacts of external environmental factors. Ex situ populations, including those managed as conservation breeding programs with species recovery aims, as well as those that do not have reintroduction goals but are managed for long term population sustainability, suffer from the same extinction risks as small and …

Development Of Molecular Diagnostic Tools For Mycobacterium Species, Hillary Bengtson

Electronic Theses and Dissertations

This dissertation focuses on the development of diagnostic tools for mycobacteria using hybridization based technologies including binary deoxyribozyme (BiDz) sensors and microarrays. The genus Mycobacterium, is a diverse group of bacteria containing 150+ species including M. tuberculosis (M.tb) and non-tuberculous mycobacteria (NTM) which exhibit a range of pathogenicity, drug susceptibility and growth characteristics. M. tuberculosis (M.tb) is the causative agent of tuberculosis (TB) and the leading cause of infectious disease related deaths worldwide. The control of TB is limited by the lack of sensitive and specific diagnostic tools available at the point of care (POC). The studies presented here illustrate …

Reproductive Life History And Signal Evolution In A Multi-Species Assemblage Of Electric Fish, Joseph Waddell

Electronic Theses and Dissertations

Animals that co-occur in sympatry with multiple closely-related species use reproductive mate attraction signals not only to assess the quality of a potential conspecific mate (sexual selection), but also to discriminate conspecifics from heterospecifics (species recognition). However, the extent to which sexual selection and species recognition may interact, or even conflict, is poorly known. Neotropical electric fish offer unrivaled opportunities for understanding this problem. They generate simple, stereotyped mate attraction signals that are easy to record and quantify, and that are well-understood from the neurobiological perspective. Additionally, they live in electrically-crowded environments, where multiple congeners live and reproduce in close …

Competition And Community Interactions Of Two Generalist Herbivores, Elizabeth Ellen Barnes

Electronic Theses and Dissertations

Competition can have far-reaching consequences for the fitness and distribution of many organisms. In herbivorous insects, competition mediated by a third organism is more common than direct competition and has a strong effect on insect communities; yet most research on indirect competition among herbivores focuses on dietary specialists, and those studies that do include generalists tend to rear them on agricultural crops. My project examines species interactions at three levels: intraspecific competition (within species), interspecific competition (between species), and ecosystem engineering effects at the community level. I studied competition and community interactions of two temporally-separated species of herbivorous insects, western …

From Dude To Dad: A Study On Prenatal Fatherhood And Its Representation In Theatre, Michael Nilsson

Electronic Theses and Dissertations

A man in the preparatory phase for parenthood with his first child can go through a lot of extreme emotional highs and lows, depending upon the man's economic, relationship, and physical status, as well as community pressures and support. In preparation to portray an array of prenatal fathers in a showcase of scenes, I have read an assortment of plays and scholarly sources. In reading a large sample of prenatal plays, I have extracted several possible emotional changes within a man's psyche. I also analyzed the social rationale behind these changes through the writings of sociologists and other scholarly sources. …

Synaesthetics, Samantha Turner

Electronic Theses and Dissertations

Synaesthetics is a new philosophy of the arts. Expanding on its predecessors, aesthetics and its many branches of thought, Synaesthetics bridges the long-standing explanatory gap across the disciplines of science, spirituality, and art. The arts become the vehicle of exploring new ways to synthesize and study their cognitive effects and implications on aesthetes, be they audience or creators. The examination of a synthesis in color and sound, inspired by research in synaesthesia, is a model for explaining the new philosophy, as well as investigating its impact. Theatre is introduced as the most valuable art form with which to engage this …

Planting Seeds: Life Stories Of Awakening Self-Awareness, Aixa Mendez

Electronic Theses and Dissertations

Using real-life stories written by female offenders, Planting seeds - Life Stories of Awakening Self-Awareness seeks to identify the systematic challenges these females may have faced, that in most cases, are the root-causes of their derailment from the societal norms of conduct. Applying the concepts of community and social justice and equality as a lens, this work will attempt to corroborate, as a universal postulate, that the process of sharing life stories can have transformative effects on the individuals and that theatre techniques, such as theatre games and scripting can help identify those impediments to restoring lives. Key to the …

Exploring Interactions Between Adult English Learners And Their Teachlive Digital Character Peers, Ting Yan

Electronic Theses and Dissertations

Peer interaction is an important part of language learning. The results of previous studies showed advantages and disadvantages of peer interaction between native speakers and English learners. Using the educational simulation platform TeachLivE as the interaction platform, this qualitative descriptive case study explored the possibilities of bridging the gap between classroom language practice and real-life second language communication. The study recruited eight participants for a task-based interaction project. Using conversation analysis, the study revealed details in communication between adult English learners and their digital character peers. During the interactions, the participants were actively involved and the most frequent communication patterns …

The Effect Of Artificial Light Pollution On Orientation Of Hatchling Loggerhead Sea Turtles (Caretta Caretta) In The Grand Strand Region, South Carolina, Emily S. Asp

Electronic Theses and Dissertations

Sea turtle hatchlings primarily utilize sight to detect differences in elevation and light intensity present along the horizon to navigate from the nest to the water’s edge. The addition of artificial lights can cause visual misdirection, resulting in disorientation (aimlessly wandering in circular paths) or misorientation (moving in distinct paths away from ocean). Extensive research has been done on effects of high levels of artificial light but little on effects of comparatively lower levels of artificial light on hatchling sea turtle orientation. This study examined these lower intensity areas to identify if there is a threshold of artificial light above …

The Spatial Ecology Of The Southern Copperhead In A Fragmented And Non-Fragmented Habitat, Megan Veronica Novak

Electronic Theses and Dissertations

Habitat fragmentation may alter the spatial ecology of organisms inhabiting the fragmented landscape by limiting the area of habitat available and altering microhabitat features. I quantified and compared movement of southern copperheads (Agkistrodon contortrix contortrix) in a fragmented and non-fragmented habitat to determine the effects of habitat fragmentation on the spatial ecology of the southern copperhead. Effective distance moved by each individual was measured by the use of thread bobbins attached via medical tape to the posterior quarter of the snake. Straight-line distance moved and occupied area were calculated with the GPS coordinates recorded at each snake sighting. Straight-line distance …

Sources And Long-Term Trends In Fecal Bacteria Contamination In The Fresh And Marine Waters Of The Grand Strand, Cara E. Schildtknecht

Electronic Theses and Dissertations

Microbial water quality is of significant concern in the two watersheds of the Grand Stand. Polluted runoff, malfunctioning septic tanks, and centralized sanitary sewer failures are common sources of fecal bacteria contamination in coastal areas and pose a threat to human health through recreational use of waterbodies and shellfish consumption. Volunteer water quality monitoring programs are crucial in expanding upon assessments of fecal bacteria contamination by regulatory monitoring. Bacteria monitoring data collected by volunteers and Coastal Carolina University’s Environmental Quality Laboratory has been used to identify sites to be investigated by microbial source tracking. Microbial source tracking has been used …

A Chemical And Genetic Approach To Study The Polyamine Transport System In Drosophila, Minpei Wang

Electronic Theses and Dissertations

Polyamines are small cationic molecules that play important roles in most vital cellular processes including cell growth and proliferation, regulation of chromatin structure, translation and programmed cell death. Cellular polyamine pools are maintained by a balance between biosynthesis and transport (export and import). Increased polyamine biosynthesis activity and an active transport system are characteristics of many cancer cell lines, and polyamine depletion has been shown to be a viable anticancer strategy. Polyamine levels can be depleted by α-difluoromethylornithine (DFMO), an inhibitor of the key polyamine biosynthesis enzyme ornithine decarboxylase. However, malignant cells often circumvent DFMO therapy by up-regulating polyamine import; …

The Actin-Severing Protein Cofilin Is Downstream Of Neuregulin Signaling, Is Regulated By The Tumor Suppressor Merlin, And Is Essential For Schwann Cell Myelination, Nicklaus Sparrow

Electronic Theses and Dissertations

Myelination is a complex process requiring coordination of directional motility and an increase in Schwann cell (SC) size to generate a multi-lamellar myelin sheath. Regulation of actin dynamics during myelination is poorly understood. However, it is known that myelin thickness is related to the abundance of neuregulin1-type III (NRG) expressed on the axon surface. NRG binding to ErbB2/3 receptors on the Schwann cell surface initiates signaling cascades necessary for myelination. We identify cofilin1, an actin depolymerizing and severing protein, as a downstream target of NRG-ErbB2/3 signaling in rat SC. A five minute exposure of SCs to NRG triggers phosphorylation of …

Development Of Binary Composite Solid Microparticles For Improved Intranasal Absorption Of Low Permeation Drug Molecules, Dipy Madhukar Vasa

Electronic Theses and Dissertations

The objective of this work was to introduce a novel formulation strategy for intranasal delivery of two low permeation candidates: levodopa (L-DOPA; antiparkinsonism drug) and ribavirin (RBVN; an antiviral drug). The central hypothesis states that preparation of binary composite microparticles with Pluronic® triblock copolymers (polyethylene glycol-polypropylene glycol-polyethylene glycol) should allow increased drug transport across nasal mucosal tissue relative to drug alone. Testing the hypothesis necessitated execution of specific aims directed to addressing issues inherent to the proposed approach. The work herein is presented with respect to two separate subjects: (1) material understanding and (2) formulation development. In the first two …

Workplace Bullying In Certified Rehabilitation Counselors And Levels Of Depression As Measured With The Bdi®-Ii And Wpvb, Mary R. Shuma Rudberg

Electronic Theses and Dissertations

Certified rehabilitation counselors (CRCs) are required to work with one of the nation’s most vulnerable populations—people with disabilities. In order for CRCs to deliver optimum services and stay mentally nourished, a healthy working environment is essential. Workplace bullying is defined by WBI (2014) as “repeated, health harming mistreatment of one or more persons.” Workplace bullying can take many forms, such as threats, humiliation, intimidation, sabotaging a target’s work, and verbal and physical abuse.

The purpose of this study was to determine whether there is a prevalence in CRCs’ experiencing workplace bullying and their levels of depression. The dependent variables included …

Getting To The Heart Of The Matter: Understanding Relational Satisfaction In Modern-Day Couples, Heather Putney

Electronic Theses and Dissertations

This mixed-methods study is the first of its kind to collect large-scale qualitative and quantitative data from diverse couples. The purpose of the research was to determine what factors (Internal, Relational, or External) most impact relational satisfaction in modern-day couples. Four hundred fifty three participants that represented diverse sexual orientation, age, social economic status, and relational commitments were asked to answer a survey that contained Likert-like scales and open-ended questions to identify what factors most influence their relational satisfaction. The answers were coded and grouped into internal, relational, and external factors. Rich descriptions of the qualitative results are included. The …

The Relationship Between Testing Frequency And Student Achievement In Eighth-Grade Mathematics: An International Comparative Study Based On Timss 2011, Ufuk Guven

Electronic Theses and Dissertations

The purpose of this study was to examine the relationship between quiz frequency and student achievement in eighth-grade mathematics as measured by TIMSS. The more specific goal of the study was determining the best quiz frequency (daily, weekly, monthly, no quizzes) and student achievement relationship for an eighth-grade mathematics course. The study investigated the above-mentioned relationship in all of the eighth-grade of participant countries combined, as well as in four specific countries: Korea, Singapore, Turkey, and the United States. Another goal of the study was to determine high performing and low performing countries’ quizzing practices, and to determine the best …

Emotions, Intuitions And Risk Perception In Critical Care, Oleksandr Dubov

Electronic Theses and Dissertations

The theory of decision-making as it applies to bioethics and healthcare assumes a rational decision maker: someone who knows all his alternatives, has clear preferences, can rank and weigh risks and benefits of an intervention, and always acts in his own best interests. However, the growing body of research from the field of decision science shows that, in reality, such a purely rational decision maker does not exist. Instead, patients are rational within personal or environmental constraints such as uncertainty or ambiguity in which non-rational approaches such as emotion and intuition are instrumental. This issue is particularly important in critical …

An Organizational Ethics Framework To Balance Individual Privacy And Population Interests Regarding Genetic Technologies, Christine Trani

Electronic Theses and Dissertations

The American culture holds the right to privacy as one of the most esteemed rights for individuals. As such, the culture adamantly defends the right to privacy to ensure individuals have the opportunity to live freely. In the American healthcare system, the right to privacy is critical for individual autonomy. However, genetic science has pushed this boundary as it emphasizes the interdependency between individual and population health. Genetic technologies for healthcare have been increasing at an exponential rate since the early 2000s. Their implantation into clinical care has been a slower process due to ethical dilemmas. Specifically, ethical dilemmas revolve …

The Normative Approach Of The Catholic Tradition In The Ethical And Religious Directives For Resolving Ethical Dilemmas Regarding Medical Technology, David G. Garvis

Electronic Theses and Dissertations

The dissertation engages the Catholic Tradition enunciated in the Ethical and Religious Directives for Catholic Health Care Services to provide a normative approach for resolving ethical dilemmas regarding pivotal breakthroughs in medical technology.

This normative ethical approach has two components: a normative framework for Catholic health care ethics that adopts practical ethical principles as enunciated in the Ethical and Religious Directives (Chapter 2) and secular decision-making models in organizational and clinical ethics that are consistent with the Catholic Tradition (Chapter 3).

At the end of the theoretical analysis in these chapters, the conclusion to Chapter 3 explains how this normative …

Clients' Experiences Of Recovery-Oriented Care For Schizophrenia: A Qualitative Research Study, Sarah A. Hamilton

Electronic Theses and Dissertations

A recovery model of care has been widely accepted and instituted both in the U.S. and internationally, but research suggests that the model has not been employed uniformly. While existing research has focused on creating consensus regarding application of the model, the lived experience of those receiving the care has not yet been considered. In order to address this gap, the present study proposed a qualitative analysis of mental health consumers’ experiences of recovery-oriented care for schizophrenia. Potential participants were recruited through a Regional Mental Health Board and the author individually interviewed four participants in semi-structured interviews. A qualitative analysis …

Improved Characterization And Analysis Strategies For Uv-Lif Bioaerosol Instrumentation: Lab And Field Application, Nicole Justine Savage

Electronic Theses and Dissertations

Atmospheric particles of biological origin, also referred to as bioaerosols or primary biological aerosol particles (PBAP), are important to various human health and environmental systems. There has been a recent steep increase in the frequency of published studies utilizing commercial instrumentation based on ultraviolet laser/light-induced fluorescence (UV-LIF), such as the WIBS (wideband integrated bioaerosol sensor), for bioaerosol detection both outdoors and in the built environment. Significant work over several decades supported the development of these technologies, but efforts to systematically characterize the operation of new commercial sensors has remained lacking. Specifically, there are gaps in the understanding of how different …

Statistical Shape And Intensity Modeling Of The Shoulder, Irene Sintini

Electronic Theses and Dissertations

Anatomical variability in the shoulder is inherently present and can influence healthy and pathologic biomechanics and ultimately clinical decision-making. Characterizing variation in bony morphology and material properties in the population can support treatment and specifically the design, via shape and sizing, of shoulder implants. Total Shoulder Arthroplasty (TSA) is the treatment of choice for glenohumeral osteoarthritis as well as bone fracture. Complications and poor outcomes in TSA are generally influenced by the inability of the implant to replicate the natural joint biomechanics and by the bone quality around the fixation features. For this reason, knowledge of bony morphology and mechanical …

Tobacco Use, Cessation, And Locus Of Control Among College Students, Bernard Ambe

Electronic Theses and Dissertations

ABSTRACT

The purpose of this study was to (a) determine the locus of control among American college students (b) determine if tobacco use or cessation correlate with any demographic variables to better understand the efficacy of tobacco interventions and help design an intervention most effective in the prominent LOC of college students.

The Global Adult Tobacco Survey (GATS) was modified for the purposes of this study and used to determine demographic factors and tobacco usage status. The modified GATS survey also included the LOC questionnaire which yielded the data. Seventy-four responses were recorded. The mean locus of control scores were …

Cloning And Expression Of Bovine Alpha S1 Casein Peptides Of Variable Size And Position Of Sppep Inhibitor Sequence, Avleen Kaur Vishram

Electronic Theses and Dissertations

Eurygaster integriceps Puton (Sunn pest) is the most damaging insect pest of wheat in areas of North Africa, Eastern Europe and Western and Central Asia. Sunn pest injects an enzyme characterized as a prolyl endylprotease (spPEP) into wheat grains that digests the gluten protein (Darkoh et al., 2010). Previous studies have shown that casein peptides generated by Lactobacillus species have inhibitory effects on human (hPEP) and bacterial prolyl endoproteases (bPEP) which makes casein a good natural candidate to inhibit spPEP. Developing biopesticides for food products from αS1 casein is complicated due to some allergenic amino acid sequences. Ruiter et al …

The Influence Of The Invasive Chinese Tallow (Triadica Sebifera) Leaf Litter On Aquatic Chemistry And Microbial Community Composition, Raymond D. Montez

Electronic Theses and Dissertations

Global climate change and anthropogenic activity have facilitated the movement and invasive potential of nonnative plants in native environments. These invasions can have negative effects on ecosystem diversity and function. The nonnative and invasive plant, Chinese Tallow (Triadica sebifera), has already invaded much of the south eastern US where it is outcompeting native tree species and changing ecosystem diversity in a variety of habitats. Leaf litter from the Chinese tallow has been shown cause changes in dissolved oxygen and pH in the aquatic environment. Turbidity is also affected when Chinese tallow litter is present in water. A series of …