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Don't Go Unless You Mean It : A Novel With Critical Afterword : Heteronormative Masculine Performance In Contemporary Fictions Of The Rural American South., Nathan N. Gower May 2017

Don't Go Unless You Mean It : A Novel With Critical Afterword : Heteronormative Masculine Performance In Contemporary Fictions Of The Rural American South., Nathan N. Gower

Electronic Theses and Dissertations

This dissertation consists of a full-length novel for an adult audience as well as a substantial critical afterword to elucidate and complicate germane thematic concerns of the creative artifact. The novel, leaning on the rich traditions and many genre conventions of fictions of the American south, tells the story of an unlikely underground coal miner in Blue Banks, a fictional southern town set in the caverns and rolling hills of the western Kentucky coal fields. The narrative follows its fish-out-of-water protagonist, Cody Culver, a fledgling academic who thought he had escaped his fate as a third-generation coal miner when he …

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Development And Degradation Analysis Of Novel Micro And Nanostructured Transition Metal Oxide (Tmo) Anodes For Aqueous Sodium Ion Batteries., Santanu Mukherjee May 2017

Development And Degradation Analysis Of Novel Micro And Nanostructured Transition Metal Oxide (Tmo) Anodes For Aqueous Sodium Ion Batteries., Santanu Mukherjee

Electronic Theses and Dissertations

One of the primary motivations driving battery technology research is the need to develop cleaner and more efficient energy storage systems. The portable electronics industry has developed exponentially, especially over the last couple of decades and therefore the importance of efficient electrochemical energy storage systems cannot be overstated. Li-ion batteries have been the predominant rechargeable energy in use, however, they have their own particular drawbacks viz. flammability of the electrolyte, expensive mining of the Li metal etc. This is where the importance of Na-ion batteries lie. This research focuses on using existing transition metal oxides (TMOs) and tuning their crystal …

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Novel Statistical Approaches For Missing Values In Truncated High-Dimensional Metabolomics Data With A Detection Threshold., Jasmit Sureshkumar Shah May 2017

Novel Statistical Approaches For Missing Values In Truncated High-Dimensional Metabolomics Data With A Detection Threshold., Jasmit Sureshkumar Shah

Electronic Theses and Dissertations

Despite considerable advances in high throughput technology over the last decade, new challenges have emerged related to the analysis, interpretation, and integration of high-dimensional data. The arrival of omics datasets has contributed to the rapid improvement of systems biology, which seeks the understanding of complex biological systems. Metabolomics is an emerging omics field, where mass spectrometry technologies generate high dimensional datasets. As advances in this area are progressing, the need for better analysis methods to provide correct and adequate results are required. While in other omics sectors such as genomics or proteomics there has and continues to be critical understanding …

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Using An Audience Response System To Calibrate Dental Faculty Assessing Student Clinical Competence., Sean A. Aiken May 2017

Using An Audience Response System To Calibrate Dental Faculty Assessing Student Clinical Competence., Sean A. Aiken

Electronic Theses and Dissertations

In order to best prepare students to become competent and confident practitioners in a clinical environment upon graduating dental school, it is imperative for them to receive consistent and productive feedback from the supervising faculty. Through academic engagement, and more specifically faculty calibration, it may be possible to eliminate the disconnect that sometimes exists between faculty expectations and terminology, and those of the students. In terms of definitions, academic engagement reflects faculty scholarly development activities that support integration of relevant, current theory of best practices consistent with the school's mission, expected learner outcomes, and supporting strategies.1-6, 32 The difficulty lies …

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Exploring A Novel Nf-ĸb- Inhibiting Nanoparticle For Periodontitis Therapy., Kameswara Satya Srikanth Upadhyayula May 2017

Exploring A Novel Nf-ĸb- Inhibiting Nanoparticle For Periodontitis Therapy., Kameswara Satya Srikanth Upadhyayula

Electronic Theses and Dissertations

Periodontitis is an infection-driven inflammatory disease characterized by gingival inflammation and bone loss. The NF-ĸB signaling pathway is pivotal in osteoclastogenesis and infection-induced pro-inflammatory responses. The use of nanoparticles as a vehicle to deliver drug increases stability, loading capacity, and facilitates transmembrane transportation. The hypothesis was that a novel nanoparticle carrying therapeutic NBD inhibitory peptides (NBD-nanoparticles) will inhibit measures of periodontal disease. In this project, we tested the nanoparticles for their ability to directly inhibit osteoclastogenesis and inflammation as an original strategy for periodontitis therapy. We also tested the capability of the nanoparticles to inhibit gingival inflammation and alveolar bone …

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Uncovering Exceptional Predictions Using Exploratory Analysis Of Second Stage Machine Learning., Aneseh Alvanpour May 2017

Uncovering Exceptional Predictions Using Exploratory Analysis Of Second Stage Machine Learning., Aneseh Alvanpour

Electronic Theses and Dissertations

Nowadays, algorithmic systems for making decisions are widely used to facilitate decisions in a variety of fields such as medicine, banking, applying for universities or network security. However, many machine learning algorithms are well-known for their complex mathematical internal workings which turn them into black boxes and makes their decision-making process usually difficult to understand even for experts. In this thesis, we try to develop a methodology to explain why a certain exceptional machine learned decision was made incorrectly by using the interpretability of the decision tree classifier. Our approach can provide insights about potential flaws in feature definition or …

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Withaferin A Synergistically Enhances The Effects Of Paclitaxel Against Lung Cancer., Al Hassan Kyakulaga May 2017

Withaferin A Synergistically Enhances The Effects Of Paclitaxel Against Lung Cancer., Al Hassan Kyakulaga

Electronic Theses and Dissertations

Lung cancer is the leading cause of cancer-related deaths among both men and women in the U.S and worldwide. Today, paclitaxel (PAC) or taxol alongside platinum-based drugs is the most widely used agent as the first-line regimen for advanced NSCLC. However, due to toxicity, drug resistance, solubility and efficacy issues, efficacy has plateaued. In the present study, the potential of a novel plant-derived steroidal-lactone, withaferin A (WFA), for clinical use alongside PAC to improve efficacy against NSCLC was explored. The anticancer effects of PAC and WFA alone, and in combination against the in vitro cell proliferation, cell adhesion, migration and …

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Stigma Of Mental Illness And Multicultural Counseling Self-Efficacy : Investigating The Implications Of The Multicultural Training Environment, Mental Health Literacy, And Empathy., Sarah E. Tucker May 2017

Stigma Of Mental Illness And Multicultural Counseling Self-Efficacy : Investigating The Implications Of The Multicultural Training Environment, Mental Health Literacy, And Empathy., Sarah E. Tucker

Electronic Theses and Dissertations

Research has shown that the stigma of mental illness is a pervasive social issue, in the United States and globally (Arboleda-Florez, 2008), one that has been considered by the surgeon general to be one of the single greatest barriers to addressing mental health care in the United States (U.S. Department of Health and Human Services, 1999). Furthermore, research has indicated that mental health care providers hold stigmatizing views toward people with mental illnesses at rates equal to or higher than the general public (Nordt, Rössler, & Lauber, 2006). This experience of being stigmatized because of a mental illness diagnosis by …

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Remotely Sensed Heat : Variation And Change In Surface Urban Heat Islands In A Temperate Eco-Region Of The United States., Jeremy Sandifer May 2017

Remotely Sensed Heat : Variation And Change In Surface Urban Heat Islands In A Temperate Eco-Region Of The United States., Jeremy Sandifer

Electronic Theses and Dissertations

Urban heat island (UHI) is a term used to describe increased surface and atmospheric temperatures in an urban core relative to surrounding non-urbanized areas. To examine the variability introduced into derived estimates of the surface UHI, this study constructs and compares multiple remotely sensed indicators of the surface UHI for major metropolitan cities of a temperate eco-region of the United States. The Moderate Resolution Imaging Spectroradiometer (MODIS) 8-day, 500-meter product (MOD11A2) is the source data used to calculate six different RS-derived UHI indicators for the year 2002 to 2012. The different SUHI indicators are evaluated using the Spearmans Rho rank-order …

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Man/Boy., Nick Hartman May 2017

Man/Boy., Nick Hartman

Electronic Theses and Dissertations

Verisimilitude, or the appearance of being true, is a concept I turn upside down; relating it to a guise I wear as a contemporary male in a society dictated by learned social behavior and gender norms. Cultural iconography and expected gender norms are tropes I confront within my artwork. Drawings of seemingly everyday objects act as meditations or a fetishized repetition of supposed unobtainable objects and ideals that deal with masculine societal norms. Manliness, machismo, masculinity… it is all a culturally learned and expected pose placed on all men. Coming to the realization that I do not necessarily fit …

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Fantastical Body Narratives : Cosplay, Performance, And Gender Diversity., Tiffany M. Hutabarat-Nelson May 2017

Fantastical Body Narratives : Cosplay, Performance, And Gender Diversity., Tiffany M. Hutabarat-Nelson

Electronic Theses and Dissertations

This dissertation aims to explore how the phenomenon of cosplay has been able to produce and sustain a diversity of gender expression due to its emergence from an activity-based community that emphasizes creative play. This creative energy is manifested through cosplay as an active, ritualized practice in which gender diversity is invited to be realized as a distinct possibility, resulting in a display of a full range of masculinities and femininities as well as crossplays and genderbend cosplays. I argue that cosplay can therefore be understood as a phenomenon that destabilizes the gender binary—its active practice promotes the production and …

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Targeting The Glucose Metabolism Of Myeloid-Derived Suppressor Cells (Mdscs) To Stimulate Cancer Immunity., Jaspreet Grewal May 2017

Targeting The Glucose Metabolism Of Myeloid-Derived Suppressor Cells (Mdscs) To Stimulate Cancer Immunity., Jaspreet Grewal

Electronic Theses and Dissertations

Myeloid derived suppressor cells (MDSCs) are a heterogeneous group of immature myeloid cells that are significantly increased in cancer patients and correlate with higher stage and poor prognosis. MDSCs negatively modulate anti-tumor immunity, suppress T cell activity, promote angiogenesis and increase the risk of metastasis. In this study, we report that monocytic-MDSCs (M-MDSCs) but polymorphonuclear-MDSCs (PMN-MDSCs) over-express 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatases 3 (PFKFB3), an important regulator of glycolysis. Furthermore in the melanoma model, M-MDSCs but not PMN-MDSCs suppressed T cell function which correlated with PFKFB3 over-expression and increased rate of glycolysis. PFKFB3 inhibition with the first-in-class small molecule inhibitor, PFK-158 reversed M-MDSC …

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Intraspecific Differences In Belowground Associations And Seedling Root Morphology For The Biofuel Crop, Panicum Virgatum., Erin Renee Kinnetz May 2017

Intraspecific Differences In Belowground Associations And Seedling Root Morphology For The Biofuel Crop, Panicum Virgatum., Erin Renee Kinnetz

Electronic Theses and Dissertations

The perennial C4 grass Panicum virgatum (switchgrass) is a promising bioenergy feedstock. Switchgrass is symbiotic with arbuscular mycorrhizal fungi (AMF). I examined 12 varieties of switchgrass grouped into 2 ecotypes (upland, lowland) to see if they differed in AMF abundance and root colonization using the GLBRC Variety Trials experiment. There was higher root colonization of lowland ecotype. A greenhouse experiment evaluated the role of live soil organisms in seedling establishment of 11 varieties. Live soil increased seedling survival, growth and influenced root morphology. Ecotypes differed in root architecture. Lowland developed a higher specific root length (SRL), a trait associated …

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Embeddedness And Commitment : Tracing Patterns Of Family Instability And Child Wellbeing Over Time., Heidi Michele Williams May 2017

Embeddedness And Commitment : Tracing Patterns Of Family Instability And Child Wellbeing Over Time., Heidi Michele Williams

Electronic Theses and Dissertations

This dissertation includes three quantitative papers using data from the Fragile Families and Child Wellbeing Study. Paper one, “For us or the children: Exploring the association between coparenting trajectories and parental commitment,” is situated in commitment theory and estimates latent growth curves. Findings suggest that unmarried parents’ coparental relationships are: 1) strong across the first five years of their children’s lives, and 2) influencing parental commitment at year 5. Paper two, “Maternal partnership transitions and coresidence with extended kin,” is situated in life course theory and estimates fixed and random effects models. Findings suggest that unmarried versus married mothers …

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Parental Opinions About Prenatal Genetic Screening And Selective Abortion For Down Syndrome., Laura E. Holt May 2017

Parental Opinions About Prenatal Genetic Screening And Selective Abortion For Down Syndrome., Laura E. Holt

Electronic Theses and Dissertations

Recent advancements in the field of genetic testing have made it easier to prenatally identify the presence of Down Syndrome in a fetus. The purpose of this study was to examine the opinions of parents who are currently raising a child with Down Syndrome towards genetic screening and selective abortion for the condition, as well as any potential effects of this process on their families. A series of individual interviews with twenty parents was conducted. An inductive methodology was used to analyze interview data. The key findings indicate that parents’ perspectives of the role of the physician in the genetic …

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Environmental Factors, Not Plants, Contribute To Functional Diversity Of Soil Bacteria In The Dunes Of Lake Michigan., Andrea Stark Howes May 2017

Environmental Factors, Not Plants, Contribute To Functional Diversity Of Soil Bacteria In The Dunes Of Lake Michigan., Andrea Stark Howes

Electronic Theses and Dissertations

Soil bacteria play important roles in nutrient cycling and other ecosystem functions, and many biotic and abiotic factors can influence bacterial functional diversity. The goal of this field study was to examine differences among bacterial communities in sand dunes of Lake Michigan. I used Biolog Ecoplates™ to compare bacteria functional diversity associated with four different plant species: the native dune-building grass Ammophila breviligulata, invasive species Leymus arenarius and Gypsophila paniculata, and native legume Lathyrus japonicus across 13 sites in Michigan, representing a gradient in abiotic factors such as precipitation and temperature. I found no differences in bacterial function associated with …

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Treg Regulation In Periodontal Disease During Pregnancy., Aislinn Leah Hays May 2017

Treg Regulation In Periodontal Disease During Pregnancy., Aislinn Leah Hays

Electronic Theses and Dissertations

Background: Although pregnancy is prone to induce more severe periodontal inflammation and tissue damage, its mechanism remains elusive. Periodontal diseases during pregnancy are associated with adverse pregnancy outcomes including preterm birth or low birth weight. Animal models are ideal for investigating immunological mechanisms in periodontal disease. With a newly modified ligature-induced disease model, we managed to develop periodontal disease in pregnant mice and investigate the immunological mechanism of more severe symptoms during pregnancy. Hypothesis: We hypothesis that P. gingivalis infection during pregnancy will lead to a down-regulation of Treg cells, therefore causing increased inflammation and disease severity. Methods: A ligature-induced …

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The Role Of The Planetarium In Students' Attitudes, Learning, And Thinking About Astronomical Concepts., William Raymond Thornburgh May 2017

The Role Of The Planetarium In Students' Attitudes, Learning, And Thinking About Astronomical Concepts., William Raymond Thornburgh

Electronic Theses and Dissertations

The purpose of this study was to examine the role of the planetarium on students while learning astronomy. The main goals of this study were to evaluate changes in students’ attitudes towards astronomy, whether students learned and retained more knowledge due to planetarium-enriched instruction, and how the planetarium helped students think about astronomical concepts. The framework that guided this study was the Contextual Model of Learning (CML) (Falk & Dierking, 1992; 2000), which includes three overlapping contexts that contribute to the overall learning experience in informal science venues - the personal, physical, and sociocultural contexts. The planetarium program was successful …

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Enhancing Cell Therapy For Ischemic Cardiomyopathy., Michael J. Book May 2017

Enhancing Cell Therapy For Ischemic Cardiomyopathy., Michael J. Book

Electronic Theses and Dissertations

Cardiac cell therapy using cardiac mesenchymal cells (CMC) significantly reduces ventricular dysfunction in patients with ischemic cardiomyopathy. Despite the improvement in function, a modest number of CMCs survive in the heart post-transplantation. In this study, we sought to improve the survival and retention of transplanted CMCs to prolong the therapeutic benefits afforded by cardiac cell therapy. To do this, we targeted the enzyme telomerase (TERT), known to be active in some highly proliferating cells (e.g. germ, stem). TERT is responsible for preventing telomere attrition, thereby allowing continued proliferation. TERT has also been shown to be protective, improve cell migration and …

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The Effect Of Caffeine On Fecundability : Differences In Coffee, Tea, And Cola Consumption., Emily Kathleen Steinmetz May 2017

The Effect Of Caffeine On Fecundability : Differences In Coffee, Tea, And Cola Consumption., Emily Kathleen Steinmetz

Electronic Theses and Dissertations

This study examined whether intake of caffeinated beverages (coffee, tea, and cola) was associated with fecundability (time to pregnancy) in a prospective cohort study. Data from 470 women from the Mount Sinai Study of Women Office Workers (1990-1994) were analyzed. Intake of coffee, tea, cola, and other variables were recorded in daily diaries and calculated as menstrual cycle level means for up to 20 cycles. Pregnancy was assayed using hCG and confirmed by physician diagnosis. The associations of caffeinated beverages with the probability of becoming pregnant during a given cycle were determined using discrete survival analysis, adjusted for potential confounders. …

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Sonic Intolerance : Aural Yellowface During The Golden Age Of American Radio., Greyson Perry Neff May 2017

Sonic Intolerance : Aural Yellowface During The Golden Age Of American Radio., Greyson Perry Neff

Electronic Theses and Dissertations

The position of the Asian in the American popular imagination has a long history, stretching back to nineteenth century vaudeville theatrical performances and remaining largely unchanged throughout the twentieth and into the twenty-first century. Portrayed as simultaneously cunning and ignorant, spiritual and corrupt, or submissive and sexualized, Oriental stereotypes have remained firmly entrenched in popular culture. While perceptions of race exist largely in a visual sense, a closer look at how people heard racial differences opens up new avenues for scholarly interpretation of the social construction of race and the shifting notions of citizenship. This thesis will investigate how listeners …

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Function Of The Enterobactin Operon Of A. Actinomycetemcomitans In The Presence Of Catecholmines And Iron., Taylor Johnson May 2017

Function Of The Enterobactin Operon Of A. Actinomycetemcomitans In The Presence Of Catecholmines And Iron., Taylor Johnson

Electronic Theses and Dissertations

Background: Aggregatibacter actinomycetemcomitans (Aa) possesses a two-component system, QseBC, which is key in biofilm formation/virulence and is activated in the presence of iron-catecholamine complexes. Aa does not synthesize enterobactin, a catechol-based siderophore, yet possesses the machinery for recognition and uptake. We hypothesize that Aa is able to acquire iron by catecholamine mediation through the enterobactin receptor/transporter. Methods: By insertional mutation, we attempted to delete the enterobactin permease from the genome using suicide vector pJT1. A growth curve of truncated mutant ΔfepA was also conducted to observe growth in the presence of iron and catecholamines. Statistical significance was determined by ANOVA …

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Electronic Nose For Analysis Of Volatile Organic Compounds In Air And Exhaled Breath., Zhenzhen Xie May 2017

Electronic Nose For Analysis Of Volatile Organic Compounds In Air And Exhaled Breath., Zhenzhen Xie

Electronic Theses and Dissertations

Exhaled breath is a complex mixture containing numerous volatile organic compounds (VOCs) at trace levels (ppb to ppt) including hydrocarbons, alcohols, ketones, aldehydes, esters and other non-volatile compounds. Different patterns of VOCs have been correlated with various diseases. The concentration levels of VOCs in exhaled breath depend on an individual subject’s health status. Therefore, breath analysis has great potential for clinical diagnostics, monitoring therapeutic progress and drug metabolic products. Even though up to 3000 compounds may be detected in breath, the matrix of exhaled breath is less complex than that of blood or other body fluids. Breath analysis can be …

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Pediatric Anxiety And/Or Depression Problems : Associations With Pm10, Fly Ash, And Metal Exposure., Abby Nicole Burns Hagemeyer May 2017

Pediatric Anxiety And/Or Depression Problems : Associations With Pm10, Fly Ash, And Metal Exposure., Abby Nicole Burns Hagemeyer

Electronic Theses and Dissertations

Background: In the last several decades, the use of coal has become more prevalent in turn increasing the amount of coal ash being produced. Coal ash, the by-product of coal combustion, is composed of small particles that contain essential elements, hazardous metals, polycyclic aromatic hydrocarbons, and radioactive material. While a small proportion of coal ash is reused, the majority gets discarded in open-air landfills and ash ponds. Fly ash, the major component of coal ash, can become emitted into the air and potentially contribute to the air pollution and metal exposure in the surrounding community. Few studies, particularly in the …

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Untangling The Role Of Postsecondary Education In Economic Success., Erin Smith Banjanovic May 2017

Untangling The Role Of Postsecondary Education In Economic Success., Erin Smith Banjanovic

Electronic Theses and Dissertations

This dissertation explored the relationship between postsecondary education and economic success through a person-centered lens. A sample of 365,315 employed individuals between the ages of 25 and 35 from the American Community Survey (ACS) were used in combination with data from three occupational databases (O*NET, the Occupational Outlook Handbook, the NORC occupational dataset) to examine this topic. The various sources of data were merged together by occupation to permit examination of occupational characteristics and creation of two measures of education and occupation match: 1) match in education level attained and required, and 2) match in field of study and field …

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Role Of Mir-29b-1 And Mir-29a In Endocrine-Resistant Breast Cancer., Penn Muluhngwi May 2017

Role Of Mir-29b-1 And Mir-29a In Endocrine-Resistant Breast Cancer., Penn Muluhngwi

Electronic Theses and Dissertations

Therapies targeting estrogen receptor α (ERα) including selective estrogen receptor modulators (SERMs), e.g., tamoxifen (TAM); selective estrogen receptor downregulators (SERDs), e.g., fulvestrant (ICI 182,780); and aromatase inhibitors (AI), e.g., letrozole, are successfully used in treating breast cancer patients whose initial tumor expresses ERα. Unfortunately, the effectiveness of endocrine therapies is limited as ~ 40% of breast cancer patients will eventually acquire resistance to them. The role of miRNAs in the progression of endocrine-resistant breast cancer is of keen interest in developing biomarkers and therapies to counter metastatic disease. This dissertation begins with a review on miRNAs implicated …

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Transversal Approaches And Ecological Artwork., Madison Deanna Sevilla May 2017

Transversal Approaches And Ecological Artwork., Madison Deanna Sevilla

Electronic Theses and Dissertations

This work explores systematic ecology as it relates to sculpture and language. This project exists in two parts: a written thesis and a thesis exhibition. Although both works explore ecological systems, Unseen: Visualizing Ecological Systems investigates visualizations and concepts of the ecological, whereas this thesis continues the exploration into the ramifications of disruptions in systems. Ecological systems such as the environmental, social/mental, economic, and political define the foundations of our known world and encapsulate all regions of society. No single system can function independently of the rest and all systems contain some aspect of human-system involvement. By using the work …

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Reducing Tobacco-Related Health Disparities : Exploring The Barriers And Facilitators To Smoking Cessation Among Individuals Experiencing Homelessness., Bernadette Guzman Antoon May 2017

Reducing Tobacco-Related Health Disparities : Exploring The Barriers And Facilitators To Smoking Cessation Among Individuals Experiencing Homelessness., Bernadette Guzman Antoon

Electronic Theses and Dissertations

Although the prevalence of smoking has declined in the U.S., vulnerable populations continue to suffer from tobacco-related health disparities. An estimated 68.0-80.0% of homeless adults are current cigarette smokers compared to 15.1% in the general population. The large gap in smoking rates suggests that current tobacco cessation programs designed to reduce smoking have little impact among individuals experiencing homelessness. The purpose of this study was to explore the barriers and facilitators to smoking cessation among the homeless. The second aim of this study was to explore if the barriers and facilitators to tobacco cessation differed among male smokers experiencing homelessness …

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American Emergency : Catastrophe And Culture In The U.S.A., From The Civil War To Hurricane Katrina., Lynda Kristian Mercer May 2017

American Emergency : Catastrophe And Culture In The U.S.A., From The Civil War To Hurricane Katrina., Lynda Kristian Mercer

Electronic Theses and Dissertations

This dissertation examines socio-cultural experiences of national disasters in the United States as they intersect with political rhetorics of democracy, to understand the forms and functions of state power as it is mediated through famous historical figures. Tracing the manifold possibilities from within and around the disruptive spacetimes of disaster, which sociologist Harvey Molotch describes in their ultimate function as societal “rationalizers” (371), I analyze catastrophes as contested spaces and histories that often get situated as variations on the “man vs. nature/god/man” binaries in public discourse. By analyzing the deployment of, and response to, such explanatory frameworks in the United …

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The Particulars About Particulates : Metal Exposure And Self-Regulation Of Children Living Near Coal Ash., Clara G. Sears May 2017

The Particulars About Particulates : Metal Exposure And Self-Regulation Of Children Living Near Coal Ash., Clara G. Sears

Electronic Theses and Dissertations

The use of coal combustion for electricity and the storage of coal combustion by-products known as coal ash occur across the United States and around the world. The most abundant type of coal ash, fly ash, contains small particles with metals, some of which are known neurotoxins. Fly ash is currently stored in open-air landfills and surface impoundments that allow fugitive dust to escape into surrounding communities, potentially exposing children to small neurotoxic particles. This dissertation uses preliminary data from a larger cross-sectional study to investigate the relationship between particulate matter exposure, metal exposure, and problems with self-regulation. Recruitment of …

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