Digital Commons Network^™

Corrosion Protection Assessment Of Offshore Wind Turbine Substructures Using Beasy Cp Simulation Analysis, Chuan-Yang Wan, Hung-Hua Sheu, Sheng-Yu Wang, Yao-Ming Wang, Wei-De Chen, Ming-Yuan Lin, Hung-Bin Lee

Journal of Marine Science and Technology–Taiwan

This study investigates the corrosion protection assessment of offshore wind turbine substructures established in the waters off Keelung, Taiwan. First, a cathodic protection system for the monopile foundation is designed and established. The Boundary Element Method (BEM) is applied using the BEASY simulation software to develop a 3D geometric model for cathodic protection. In the steel monopile simulation analysis, the exposed marine environment is set based on the sea conditions of the Keelung small boat marina, including parameters such as salinity, resistance, and polarization curves, to establish an effective cathodic protection system for underwater structures. By simulating these parameters, a …

Face-To-Face Versus Distance Education In Competence-Based Maritime Education And Training, Clara Borén, Marcella Castells-Sanabra, Manel Grifoll

Journal of Marine Science and Technology–Taiwan

The COVID-19 pandemic created significant challenges for higher education, with universities being shut down and face-to-face teaching and assessment shifting to an online format. This presented an opportunity to focus on the continuity of learning through distance education, especially in the maritime context, due to the on-board training requirements, and even though five years have passed, this shift has reshaped the education landscape, proving that remote learning has come to stay.

At the Barcelona School of Nautical Studies, we have developed a weather routing software in the framework of distance education and teaching innovation. We conducted a teaching trial alternatively …

A Bibliometric And Visualization Analysis Of Global Giant Clam Research, Chia-Hsiang Chen, Chih-Hsien Chang

Journal of Marine Science and Technology–Taiwan

In this study, bibliometric analysis and visualization tools were used to investigate the academic network and knowledge structure surrounding global giant clam research. A total of 551 relevant publications from the Web of Science database, published from 1900 to 2024, were analyzed. The findings indicate that research on giant clams has experienced considerable growth since 2012, peaking in publication output in 2021. Sixty-six countries were represented in the study sample, with the United States, Australia, China, Singapore, and Japan being the most represented ones. Notably, the rate of international collaboration was only 29%, highlighting a need for additional integrated cross-border …

(Re)Claiming Homeplace: Dance As Embodied Resistance & Healing For Health & Spatial Justice, Preeya G. Kannan

University Honors Theses

This thesis argues that dance functions as both an upstream public health intervention and a form of radical spatial resistance; creating healing, agency, and belonging among historically marginalized communities. Drawing on bell hooks' concept of homeplace, Jasbir Puar's assemblage theory, Nancy Krieger's eco-social theory, and Katherine McKittrick's Black geographies, I position the body as both an ecological and political landscape shaped by histories of colonialism, racial capitalism, displacement, and resilience.

Through this community-based participatory research study, Homeplace, I explore dance as a form of social prescription that centers liberation rather than pathology. Movement is often reduced in public health discourse …

Proteomic Analysis Of Ammonia-Induced Stress In Chinese Hamster Ovary (Cho) Cell Cultures, David Ryan, Michael Henry, Christiana Kondylo Sideri, Esen Efeoglu, Paula Meleady

Research Outputs: 2025-Present

Ammonia (NH₃) and its ionic form ammonium (NH₄⁺) are both metabolic waste products and essential nitrogen sources within Chinese hamster ovary (CHO) cell cultures. Although necessary for amino acid synthesis, excessive accumulation in the extracellular environment can exert stress, reducing cell proliferation and impairing the efficiency of recombinant protein production. Proper endoplasmic reticulum (ER) function is critical for CHO cells as biotherapeutic producers. Previous work has linked elevated ammonia concentrations to reduced productivity via altered N-glycosylation pathways, but its broader effects on ER biology remain unclear. In this study, we applied high-resolution mass spectrometry to perform a comprehensive …

Autophagic Flux Blockade Under Hypocapnia Reveals Co2-Sensitive Regulation Of Autophagy-Lysosome Homeostasis, Naghmana Ashraf, Zhen Sun, Jeanine L Van Nostrand

Faculty, Staff and Students Publications

Hypocapnia, a reduction in partial pressure of carbon dioxide (CO2), commonly occurs in clinical contexts such as mechanical ventilation, panic disorder, and brain injury, yet its impact on cellular homeostasis remains poorly understood. Given the central role of autophagy in stress adaptation, we investigated how low CO2 influences autophagic flux and lysosomal function. We found that hypocapnia induces autophagosome accumulation while impairing cargo degradation, indicating a blockade in autophagic flux. This response was accompanied by increased lysosome biogenesis but, paradoxically, reduced autophagosome-lysosome fusion and lysosomal proteolytic activity. Mechanistically, hypocapnia promoted TFE3 dephosphorylation and nuclear translocation, driving transcriptional activation of lysosomal …

Ultrasound-Enabled Refreshable Electrochemical Sensors For Cardiac Biomarker Monitoring, Mayank Garg, Heng Guo, Myeong Namkoong, Elizabeth Zhanov, Connor Malone, Md Saifur Rahman, Ayse Akcan-Arikan, Limei Tian

Faculty, Staff and Students Publications

Cardiac troponin I (cTnI) is the gold-standard biomarker for acute myocardial infarction, yet current laboratory-based high-sensitivity assays require centralized infrastructure, trained personnel, and serial testing, limiting their suitability for real-time or continuous monitoring in resource-limited settings. Point-of-care electrochemical sensors have shown promise for rapid cTnI detection, but their reliance on antibodies as biorecognition elements and redox mediator solutions, and single-use operation restricts practical translation. Here, we report an ultrasound-enabled refreshable electrochemical biosensor for sensitive, stable, and repeatable cTnI monitoring. The device employs a cTnI-specific peptide as the biorecognition element, providing enhanced stability during storage, transport, and operation. Label-free electrochemical impedance …

2026-06-15 Message From The President, Morehead State University. Office Of The President.

Staff Congress Records

Message sent on June 15, 2026 by the President to the campus community regarding modified hours, upcoming dates of importance, Board of Regents meeting summary, and campus personnel announcements and updates.

“Between Cultural Norms And Economic Survival: Navigating Egyptian Lower And Middle Income Women’S Challenges In The Informal Versus The Formal Work: “A Case Study From Cairo”, Rowan Mahmoud Abdelnazer

Theses and Dissertations

This study investigates the ongoing gender inequities experienced by low and middle-income women in Egypt’s formal and informal labor economy, specifically it is based in Cairo. Although there are many advances made globally on women's rights, yet women still face great challenges such as discrepancies in salary, fewer leadership roles and cultural expectations which put child-bearing duties before professional growth. On the one hand, flexible work for women in developing countries is through informal sector, which makes them vulnerable and serves as a source of their exploitation and insecurity (e.g., lack of social security; workplace hazards), on the other hand, …

The Human Side Of Humanitarian Work: Well-Being And Performance Among Aid Workers In Egypt, Mai Osama Kenawy

Theses and Dissertations

Well-being and productivity are widely recognized as central to the work performance of humanitarian aid workers. Despite increasing attention to staff well-being, performance within the humanitarian sector in Egypt remains stagnant or, in some cases, declining. This study examines why expanded well-being initiatives have not yielded sustained performance improvements by examining how actors' external roles, organizational factors, and individual factors affect humanitarian workers’ well-being and work performance. A mixed-methods approach was adopted, combining ten in-depth interviews with humanitarian workers from international organizations, INGOs, and local NGOs, as well as a survey of eighty workers operating in the same context. The …

Personal Data Protection In Vietnam’S Burgeoning Insurance Sector, Thi Giang Thu Pham, Thị Long Nguyễn

Washington International Law Journal

No abstract provided.

Lawrence University One Hundred Seventy-Seventh Commencement, Sunday, June 14, 2026, Lawrence University

Commencement Programs

No abstract provided.

Baseline Lymphopenia Predicts Survival In Ici-Naïve Solid Tumor Patients Receiving Immune Checkpoint Inhibitors: A Propensity-Matched Real-World Pan-Cancer Analysis., Ahmed Ismail, Nina Balanchivadze, George R Simon, Yanis Boumber

Oncology Articles

Background: Baseline lymphopenia is common among advanced solid tumors and may influence the efficacy/safety of immune checkpoint inhibitors (ICIs), but large real-world evidence is limited. We evaluated the association between baseline absolute lymphocyte count (ALC) and clinical outcomes in adults with solid tumors treated with ICIs in routine practice. Methods: We performed a retrospective cohort study using TriNetX. Adults with solid tumors who received pembrolizumab, nivolumab, or atezolizumab (ICI-Naïve) between January 2015 and June 2026 were included. Baseline ALC was measured within 30 days before first treatment and was classified as lymphopenic (ALC < 1.5 × 109/L) or non-lymphopenic (ALC ≥ 1.5 × 109/L). Propensity score matching (1:1) yielded 5249 patients per group. The index date was the first immunotherapy date, and outcomes were assessed at 6, 12, 24, 36 months, and 5 years. The primary outcome was 24-month overall survival (OS); secondary outcomes were OS at 6 and 12 months and 6-month risks of healthcare utilization, immune-related adverse events (irAEs), and serious infections; and exploratory outcomes included OS at 36 months and 5 years. All outcomes were analyzed using Kaplan-Meier analysis, Cox proportional hazards models, and risk ratios. Subgroup analysis included OS stratified by solid tumor subtypes and prior lines of therapy. Results: After matching, patients with baseline lymphopenia …

Making A Phrenological America: How The Science Of The Skull Influenced Reform Movements In The United States, Nathan C. Tamkin

History Undergraduate Senior Theses

No abstract provided.

Destination “Burning River”: Restoration And Placemaking In A Rust Belt City, Mia Compton-Engle

Geography Undergraduate Senior Theses

In 1969, the Cuyahoga River in Cleveland, Ohio caught fire from industrial pollution. Media narratives reframed the river fire as a symbol of environmental degradation, discursively transforming the Cuyahoga River from a place of industrial sacrifice to a place deserving ecological stewardship. Consequently, the river fire catalyzed the modern American environmental movement and local urban river restoration, materially transforming the Cuyahoga River from a place of industrial waste to a place of natural beauty and socioeconomic opportunity. Thus, urban river restoration presents an opportunity for novel placemaking: a local microcosm of the global turn towards urban sustainability. However, there is …

The Unspoken And The Unseen: An Analysis Of Victim Gender And Linguistic Framing Of Sexual Assault In Judicial Discourse, Sarnika Ali

Quantitative Social Science Undergraduate Senior Theses

Sexual assault is a profound legal and social crisis. However, it is also fundamentally a linguistic one. The words used, or conspicuously not used, to describe victims, perpetrators, and their actions are not neutral arbiters of fact. They are powerful mechanisms that shape perceptions of harm, attributions of blame, and assignments of credibility. The central battleground for survivors is credibility, and while a “credibility discount” is often applied to female victims, the male victim is rendered nearly invisible. This research is therefore guided by one central, overarching question: how does a sexual assault victim’s gender influence the judicial language used, …

Pharmacotherapeutic Interventions For Sensorineural Hearing Loss: A Scoping Review, Matthew Mavandi, Jack Hyler, Eric Lee, Ramanjot Singh, De Wet Swanepoel, Ashley M. Nassiri, Vinaya Manchaiah

Student Publications

Background/Objectives: Sensorineural hearing loss (SNHL) is a chronic condition with no established pharmacological treatment. Recent advances in drug-based therapies offer promising opportunities to prevent or treat SNHL. This scoping review summarizes the current landscape of pharmacotherapeutics for SNHL.

Methods: This scoping review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). A literature search of PubMed, Google Scholar, Embase, Scopus, and Web of Science was conducted in 2024 using keywords related to SNHL and pharmacotherapeutics. A review protocol was preregistered on the Open Science Framework. A systematic search of five …

Strategic Anti-Transgender Policy Diffusion: Interest Groups, Courts, And The Two-Track Politics Of Gender Regulation, Henry Danford

University Honors Theses

This thesis analyzes the strategic diffusion of anti-transgender policy in the United States following the passage of Idaho House Bills 500 and 509 in 2020. It argues that conservative lawmakers and advocacy organizations employed a coordinated "two-track" policy strategy in which transgender sports bans served as highly visible and politically popular mode legislation while identity-document restrictions advanced more quietly through courts and administrative policy. Drawing on policy diffusion theory, the Advocacy Coalition framework, and minority stress theory, the study combines qualitative policy analysis with quantitative analysis of Household Pulse Survey mental health data and Media Cloud new coverage data from …

Beyond The Best Prompt: A Coverage View Of Multilingual Reasoning, Harshiv Mistry

University Honors Theses

Multilingual LLMs reason more accurately in English than in other languages, and recent work links part of this gap to reasoning behavior: native-language traces contain fewer cognitive behaviors (verification, backtracking, subgoal setting, backward chaining) that support effective problem solving. We test whether prompting for these behaviors at inference time narrows the gap, across seven conditions varying chain-of-thought, instruction and reasoning language, and cognitive-behavior descriptions, on two models, three languages. We find that English-scaffolded reasoning is the strongest single strategy on both models, closing the Hindi gap on Qwen, though the explicit scaffold's value over plain chain-of-thought is model-dependent. Beyond aggregate …

Elucidating The Function Of Yedk In Response To Dna Damage, Hank Munro

University Honors Theses

Apurinic/Apyrimidinic (AP) sites are one of the most prevalent forms of DNA damage. These lesions arise spontaneously or during base excision repair of modified DNA bases and are potentially mutagenic in both mammalian and bacterial cells. 5-hydroxymethylcytosine binding, ES cell specific (HMCES), a protein found in eukaryotic cells, has been shown to form a stable DNA-protein crosslink with AP sites in single stranded DNA and to reduce the number of AP sites occurring either spontaneously or after alkylative DNA damage, resulting in increased genome stability. YedK, the Escherichia coli ortholog of HMCES exhibits some of the same biochemical properties as …

Effects Of Fine Sediment On The Productivity Of Stream Ecosystems In The Pacific Northwest, Veena I. Davis

University Honors Theses

Salmon are important to the culture, ecosystem and economy of the Pacific Northwest. However, populations have declined significantly since European colonization. Salmon require specific conditions for each life stage and are highly sensitive to environmental stressors. Excess fine sediment is a leading form of pollution as it degrades salmon spawning habitat and the benthos upon which their main food source, stream insects, live. To evaluate the effect of sediment pollution on food availability for salmon smolt, we conducted an experiment  estimating the amount of stream insect biomass and calories lost due to sediment pollution. We counted insects on substrate samples …

Mycelial Modeling: Teaching Biology Students Statistical Modeling With Mushrooms, Colette Wolf

University Honors Theses

This paper summarizes and describes the development of a set of learning materials that were created to educate students and professionals from other fields in statistical modeling techniques. These materials are primarily aimed at biology students, but are still intended to be useful for anyone who is interested in incorporating decision trees and random forest models into their personal research in the future. By directing the reader towards the JMP software, these materials navigate around the statistical knowledge base and coding implementation practices that otherwise would serve as a barrier to learning statistical modeling techniques, and instead focus on the …

Skeletons Vs. Mummies: Osteological Trauma On Bog Bodies As A Measure For Cultural Change In Ancient Europe, Miranda Hoodenpyl

University Honors Theses

Bog bodies are some of the most well known archaeological finds in the world, and are preserved human remains found in wetlands. Researchers use the information stored in the bones of bog skeletons and mummies to learn about cultural lifestyles, travels, diet, and diseases throughout time in Northern Europe and the British Isles. Through multiple cultural changes and migration, the "bog body phenomenon" has remained an unusual treatment displayed throughout time. This literature review looked at skeletal trauma on bog remains to identify cultural change over time in Northern Europe and the British Isles, spanning the Neolithic, Bronze, Iron, and …

Why Student Research Matters: A Graduate Student’S Perspective, Jessica L. Hensley

The Journal of Integrative Physiology

Research fundamentally changes how students engage with knowledge. Rather than memorizing established facts, students learn to question, analyze, and contribute to the body of knowledge within their field (1). This shift supports deeper understanding and promotes critical thinking skills by encouraging active construction of knowledge (1). It also exposes students to the process of engaging with scientific literature and integrating information within the context of their research (2).

In my experience, research requires individuals to confront uncertainty. Experiments do not always produce exact results, and methods can require modification. Through this process, students develop adaptability, persistence, and the ability to …

Literature Carries Philosophy’S Open Secret: On Derrida’S Reading Of Romeo And Juliet, Rajesh Sampath

Critical Humanities

This paper attempts a close reading of Derrida’s texts, particularly with a focus on his brief but significant reading of Shakespeare’s The Tragedy of Romeo and Juliet in “Aphorism Countertime” (originally published in French in 1986). We compare this short work with his more sustained engagement with the philosophy of death in Aporias (1993), which itself is an attempted critique of Heidegger’s Being and Time (1927); the latter is, arguably, the most influential work of twentieth-century continental European philosophy, particularly on issues of time, death, and authentic life. The paper tries to show that a fruitful engagement between philosophy and …

Endothelin-1 Drives Cox-2 And Prostaglandin E2 Expression In Osteoblasts Through Mapk/ Ap-1 Signaling During Periodontal Inflammation, I-Ta Lee

Articles in Press

No abstract provided.

Effects Of 850-Nm Light-Emitting Diode Photobiomodulation On Pain Intensity And Dentin Sialoprotein Levels During Canine Distalization: A Randomized Controlled Trial., Anh Ho-Quynh Nguyen

Articles in Press

No abstract provided.

Changes Of Rna Expression In Aging Periodontal Ligament Cells, Sang Wook Kang

Articles in Press

No abstract provided.

Trans-Regulation Of Heterochromatin Underlies Genetic Variation In 3d Genome Contacts In Mouse Embryonic Stem Cells., Haley J Fortin, Anna Z Struba, Arad Bustan, Christopher L. Baker

Faculty Research 2026

BACKGROUND: Genetic variation drives phenotypic diversity and disease susceptibility. Trans-acting genetic variation coordinates genome-wide chromatin changes, yet the molecular mechanisms underlying this distal regulation remain unclear. Here, we use the power of mouse genetics to investigate how genetic variation at trans-acting loci regulates three-dimensional (3D) chromatin interactions.

RESULTS: Using HiChIP to map chromatin contacts among regulatory elements in C57BL/6J and DBA/2J embryonic stem cells (ESCs), we identify 4,962 strain-differential interactions. Of these, 71% overlap chromatin accessibility quantitative trait loci (QTL), establishing that interaction variation is predominantly heritable. These differential interactions show coordinated changes in chromatin state and gene expression, with …

The Neuroprotective Effect Of Cdc42 Inhibition In The G93a Mutant Hsod1 Mouse Model Of Als, Andrea Koly

Undergraduate Theses, Capstones, and Recitals

Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative disease characterized by the selective loss of upper and lower motor neurons, leading to muscle weakness, neuromuscular junction (NMJ) degeneration, paralysis, and eventual death due to respiratory failure. Despite extensive research, effective disease-modifying therapies remain limited, underscoring the need to identify novel molecular targets involved in ALS pathogenesis. Dysregulation of Rho family GTPases has been implicated in neurodegeneration, with Rac and Rho exerting opposing effects on neuronal survival; however, the role of the closely related GTPase Cdc42 remains poorly understood in ALS. In this study, the therapeutic potential of inhibiting …