Digital Commons Network^™

Reinforcement Learning And Virtual Human Animation: A Novel Approach To Data-Driven Animation, Portraying Dynamic, Flexible Human-Like Behaviours, Vihanga Gamage

Dissertations

Virtual characters require animation capable of portraying dynamic, context-sensitive human-like behaviours. Several approaches to generating such animation have been developed, but each carries limitations. Motion capture can produce high-fidelity animation but is expensive and ill-suited to systems that must respond in real time. Physics-based reinforcement learning (RL) enables flexible, dynamic behaviour portrayal, yet relies on simulation feedback signals that are unavailable for social gestures. Supervised approaches can learn social behaviours from motion capture data but yield agents with limited flexibility and generalisation.

This thesis presents RLAnimate, a model-based, data-driven RL framework for character animation that enables a single agent to …

Difficulty In American Dramatic Literature, David Turkel

Dissertations

Speaking broadly, this dissertation explores the marginalization of American drama within the field of literary studies. In attempting to account for this marginalization, theater scholars have tended to invoke the genre’s supposed lack of “difficulty,” meaning its failure to pose meaningful interpretive challenges to its readers. However, this dissertation takes an alternative view of the matter, contending that if American drama has indeed been marginalized, it is not because literary studies departments have regarded it as intrinsically “simpler” than other literary genres; in fact, it is theater scholars who have been more likely to read the genre as simple, or …

"It Can Be Hard To Stand Up Straight In A Crooked Room:" Examining The Mediating Effects Of Black Women's Gendered Racial Identity On The Relationship Between The Strong Black Woman/Superwoman Schema And Collective Coping, Devin Willis

Dissertations

Prior research on the Strong Black Woman (SBW)/Superwoman (SW) schema has produced mixed findings. Both positive and negative outcomes of Black women’s internalization of this schema have been identified. These mixed findings may be linked to the measurement of the SBW/SW schema and the relationship with other culturally relevant variables. There have been significant positive relationships identified between Black women’s gendered racial identity (GRID) and the internalization of gendered racial stereotypes (i.e., the SBW/SW). Methods for coping with stereotypes have also been identified as influential when considering Black women’s coping behaviors.

The purpose of this study is to examine the …

Mechanistic And Evolutionary Insights Into A Group Of Nicotine And Hydroxynicotine Degrading Flavoenzymes, Zhiyao Zhang

Dissertations

Flavoprotein amine oxidases (FAOs) are key enzymes in various kinds of metabolic pathways, mediating redox reactions via flavin cofactors. While most FAOs function as oxidases that readily reduce oxygen to hydrogen peroxide, a few outliers of the FAO family act as dehydrogenases that suppress the reaction with oxygen. The molecular basis for this divergence in function remains poorly understood.

The work presented in this study investigates the fundamental mechanisms of how flavincontaining enzymes activate or suppress their reaction with different electron acceptors to achieve high turnover rates. The overall body of work is divided into three different sections that (1) …

From Colonization To Cultural Responsiveness: Examining Cultural Identity And Representation In Taiwanese Music Education, Peijyun Syu

Dissertations

The purpose of this study was to examine the Taiwanese music education system through the lenses of postcolonial theory, critical pedagogy, and culturally responsive teaching—beginning with its establishment during the colonial periods under the Japanese Empire (1895–1945) and the Chinese Nationalist regime (1945–1987), and extending to an analysis of the current curriculum. This study was guided by the following research questions:

Q1 How do current Taiwanese elementary school music textbooks address cultural responsiveness through an analysis of the cultural origins of songs, composers/artists, and instruments included in the curriculum?

Q2 What are the views of Taiwanese elementary school music teachers …

Students’ Ability To Transfer Organic Chemistry Concepts To Metabolic Reactions, Timothy Jones

Dissertations

Bridging foundational knowledge learned in prerequisite courses like organic chemistry to higher-level courses like biochemistry represents a significant challenge in science education, often hindering deeper student understanding and future knowledge application. The purpose of this dissertation was to investigate students’ ability to transfer and apply their understanding of organic chemistry when reasoning through metabolic reaction problems often seen in biochemistry courses. The research questions guiding the project were two-fold:

Q1 What are the organic chemistry reaction concepts deemed foundational to understanding metabolism by experts in the field?

Q2 What is the student’s ability to transfer knowledge of organic chemistry reactions …

Spatial Distributions And Occupancy Dynamics Of Carnivores In A Central Hardwood Forest, Maximillian Larreur

Dissertations

Extirpation of apex predators, caused primarily by anthropogenic alterations to natural environments and persecution, has led to mesocarnivore release in these areas. Mesocarnivore release is an ecological phenomenon in which mesocarnivores thrive in the absence of apex predator dominance within the carnivore hierarchy. Mesopredators fill this dominant role on the landscape as de facto apex predators, however, this can lead to changes in inter-guild species space use, predator-prey dynamics, activity patterns, and interspecific competition. Understanding patterns in wildlife spatial distributions, which indicate variability in habitat space use across spatiotemporal scales, is critical for developing effective management and conservation plans and …

Immune Modulation Affects Olfactory Glomerular Recovery In Zebrafish, Bonnie E. Ebendick

Dissertations

Adult zebrafish regenerate neurons throughout their lifetime and exhibit rapid recovery from neuronal damage with support from their immune system, making them an excellent model for studying neuroinflammation and brain repair mechanisms. When olfactory sensory neurons are lesioned, their cell death stimulates the immune system by activating microglia and other immune cells in the olfactory bulb, initiating tissue repair and neuronal replacement. This dissertation investigates how the immune system influences recovery from neuronal damage, testing the hypothesis that immune perturbation in zebrafish alters neural recovery.

To investigate the link between immune function and neuronal regeneration, zebrafish received a unilateral lesion …

The Development Of High Throughput Assays For Identification And Evaluation Of Small Molecule Modulators Of The Pri-Microrna-18a—Hnrnp A1 Interaction, Emile N. Van Meter

Dissertations

Therapeutics targeting RNA is a rapidly growing field. While only 1.5% of the human genome encodes genes for protein, over 70% o=f the human genome contains the genes for noncoding RNAs that regulate protein expression and function. Expanding the paradigm of small molecule drug discovery from traditional protein targets to include RNA would broaden the therapeutic landscape and provide new methods to modulate previously undruggable targets. miRNAs (miRs) have been found to be aberrantly expressed in many disease states, including neurodegenerative diseases and cancers making them promising therapeutic targets. The production of functional, mature miRs requires multiple proteins in a …

Cognitive And Affective Factors Related To Geoscience Academic And Career Choice, Amanda Diane Manzanares

Dissertations

Recruitment and retention continue to be a challenge for Science, Technology, Engineering, and Math (STEM) fields. Research shows that both cognitive and affective factors influence student learning, which can then shape academic and career choice. Therefore, my alternatively formatted dissertation includes three articles examining two STEM disciplines: geosciences and Interdisciplinary Environmental and Sustainability programs adding to prior research and further uncovering specific factors that could predict student educational and professional aspirations.

Regarding cognition, students often begin STEM courses with pre-existing mental frameworks, also referred to as schemas that are formed by their prior experiences. These schemas may conflict with established …

Early Care And Education Systems In The United States Of America: Voices Of The Past, Present, And Future, Timothy Harper

Dissertations

This mixed-methods study centers the voices, knowledge, and leadership of Black and Indigenous women working in Early Care and Education (ECE) while tracing how racism, sexism, and classism have shaped the field from colonization to the present day. Twenty in-depth interviews with sixteen Black and Indigenous educators across the United States are paired with secondary analyses of national workforce data to create a multilayered portrait of their professional realities. Grounded in Black feminist thought and Indigenous desire-based inquiry, the analysis surfaces six inter-locking themes: (a) enduring structural barriers that depress wages and limit advancement, (b) the day-to-day resilience that sustains …

Implementation Of Mindfulness-Based Interventions And Weekly Visits To Reduce Loneliness In Older Adults, Victoria E. Cobb

Dissertations

Implementation of Mindfulness-Based Interventions and Weekly Visits to Reduce Loneliness in Older Adults

Abstract:

Problem: Social isolation and loneliness have emerged as a significant public health issue for the older adult population. Loneliness has been linked to both physical and mental health effects. According to current literature, there is no standard intervention to treat loneliness in the older adult population.

Methods: This quality improvement (QI) project utilized a descriptive cohort design and the Visit-A-Bit screening assessment instrument. Undergraduate nursing students implemented mindfulness interventions during weekly visits over an eight-week period at an independent living facility located in the Midwest. Descriptive …

Depression Screening In The Adult Inpatient Oncology Population, Erica Bizub

Dissertations

Routinely screening oncology patients for depression is recommended due to the higher rates of depression in this population as well as the negative impact of untreated depression. The goal of this QI project is to implement a standard depression screening protocol for patients admitted to this hospital, where there is currently no standard screening protocol. There were 110 patients included in this study, and 67 (60.91%) of patients received a PHQ-9 screening. Of the patients who completed the PHQ-9, 21 (19.09%) had a positive screening, which was a score of seven or higher. While there were high rates of provider …

Nanoporous Gold Nanoparticles And Model Membrane Systems Applied To The Study Of Lipopolysaccharide (Lps), Dhanbir Lingden

Dissertations

Lipopolysaccharide (LPS), a key structural component of Gram-negative bacteria, is a major trigger of sepsis and septic shock, the systemic inflammatory conditions responsible for millions of deaths annually. Even at concentrations as low as 1 ng/mL, LPS can activate the immune system and initiate inflammatory cascades. According to the Global Burden of Disease Study 2017, sepsis accounted for 48.9 million cases globally, with 11 million deaths, emphasizing the urgent need for improved diagnostic and therapeutic strategies.

Accurate and rapid detection of LPS is vital for early intervention and improved clinical outcomes. While traditional detection methods are still widely used, modern …

Screen Foundations: How Pediatric Nurse Practitioners Can Implement ‘Family Media Use Plans’ In Primary Care To Reduce Pediatric Behavior Concerns, Katie Anderson

Dissertations

Abstract for:

Screen Foundations: How Pediatric Nurse Practitioners Can Implement ‘Family Media Use Plans’ in Primary Care to Reduce Pediatric Behavior Concerns

Problem: Parents of children 2-5 years-old increasingly reach out to PCPs for escalating behavior concerns, including when the child doesn’t listen well, is inattentive, having tantrums, meltdowns, hitting, yelling, etc. Referrals to psychiatry and/or play therapy result in long waits, or referrals not accepted. Coincidingly, toddler and preschool aged children continue to exceed daily screen time recommendations. This results in a gap of care for families with young children and externalizing behavior.

Methods: This quality improvement project addressed …

Educational Technologist Perceived Self-Efficacy During Emergency Remote Teaching Due To A Nonpharmaceutical Intervention, Katherine R. Rapp

Dissertations

This paper discusses the challenges and opportunities of educational technologists (ETs) during emergency remote teaching (ERT) in a non-pharmaceutical intervention (NPI), due to the COVID-19 pandemic. The study was guided by Albert Bandura’s social cognitive theory and self-efficacy framework. The study highlights the positive and negative reflections of self-efficacy for ETs during the transitions to different strategies in classroom teaching. It acknowledges the positive and negative effects on ETs from self-regulation, observational learning, and reciprocal determinism. The study design used was qualitative, aiming to identify the perceived self-efficacy of ETs during ERT in an NPI. Eight ETs from rural school …

The Roots Of Our Food: Relationships Are The Seeds Of Care-Based Food Heritage, Nicole E. Post, Raena D. Parsons, Adrian Boone

Dissertations

The purpose of this co-authored, general qualitative research

study was to examine food relationships between individuals,

communities, and Earth. We explored the concept of relational food

systems pertaining to engagement ideas at EarthDance Organic Farm

School and Hawai’i Institute of Pacific Agriculture. Our research

furthers understanding about how to engage people, individually and

collectively, with the land to inspire action. We argue that care-based

relationships can inspire action, helping individuals reconnect with

their food heritage by engaging with land, community, and self.

Heritage site leaders in food systems who center interconnectedness

create places where relationships between people, land, and food …

The De Mau Mau Conspiracy: The Specter Of Black Vietnam Veterans In The Exercise Of Police Power, 1968-1976, Ina Cox

Dissertations

A forgotten and bizarre event encapsulates the violent decay that characterized the pivotal years the United States endured in the wake of the Vietnam War. Black veterans—guerrilla combat-trained, politically awakened by war, and disillusioned with the entrenched racial order at home—emerged as totems in a fearful, cynical political culture wracked by violence. Men overrepresented in the projection of American power abroad now stood as symbols of its fragility within, potential vessels of retribution for centuries of domestic and global oppression. This anxiety, merging with widespread protests and political upheaval, intensified the belief that American cities stood on the brink of …

Into The Language Barrier: Analysis Of The Debates Of Charles Taylor And Jürgen Habermas With Concentration On The Importance Of Philosophy Of Language, Tom Crosby

Dissertations

Jürgen Habermas (b. 1929) and Charles Taylor (b. 1931) are two of the most important philosophers of the late 20th and early 21st centuries. Throughout their lengthy bodies of work, spanning from the 1960s and continuing today, they were frequent interlocutors, and often responded to one another’s theories and arguments. They also engaged in direct debates in edited volumes to which they both contributed, including Communicative Action: Essays on Jürgen Habermas's The Theory of Communicative Action (1991), Multiculturalism (1994), and The Power of Religion in the Public Square (2011). The goal of this dissertation is to catalogue and analyze Habermas …

The Hitching Post: American Poetry And Chinese Mythology, Xiamara Elena Hohman

Dissertations

In this dissertation, I examine the ways in which Chinese mythology has figured in American poetry, focusing particularly on the ways Chinese mythologies have served—and continue to serve—as “hitching posts,” quasi-material sites from which meaning can be created and explored. As I am defining it, a myth is a narrative that gives meaning to a lived experience. It explains what we commemorate and worship and renders meaningful both celebration and life. In the first three chapters of this study, I discuss the ways in which Chinese myths and cultural practices have been both used as hitching posts and appropriated by …

"The Divine Light Illuminates The Intellect:" The Role Of Divine Illumination In The Theology Of Meister Eckhart, John Marshall Loving

Dissertations

This dissertation is a study on the epistemological theory of divine illumination in the works of Meister Eckhart (c. 1260 - 1329 CE). Illumination, first asserted by St. Augustine, is the theory that the human intellect is incapable of achieving epistemic certainty regarding what it sensorily receives. To gain this certainty, the mind is reliant upon illumination, wherein the sensed object is known by the mind through the light of that object's divine idea, which also serves as its ontological principle. Divine illumination was the dominant epistemology in Christian thought for centuries until it began to lose its influence in …

Modernism’S Mythic Mothers: Queering Motherhood Through Classical Matrilineage, Samantha Marie Lepak

Dissertations

I position this dissertation at the intersection of modern/contemporary literature, queer/feminist theory, and ancient Greek classics in the hopes of better understanding the spaces in which they meet, engaging with writers from the late modernist era to the present in order to highlight the connections between theories, themes, and practices of queerness from the modernists forward. Using the work of H.D. and writers following in her footsteps, I argue that exploring adaptations of Greek classics written primarily by female and gender-variant authors from the modernist era forward illuminates the extent to which the classics enables writers to “think queerly,” considering …

Toward Culturally Responsive Interpretation: Native American Histories, Lifeways, And Ways Of Knowing At The High Desert Museum, Carol Fitzsimmons, Ajena Cason Rogers

Dissertations

Many public museums and historic institutions reflect settler colonial culture and are primarily non-Native led. Although these institutions are trusted, many have perpetuated cultural harm through the theft of belongings, the misrepresentation of stories and histories, and the inaccurate portrayals of cultural content. When interpreting Native American experiences, many non-Native institutions struggle to co-create culturally responsive interpretation. The purpose of this basic qualitative study was to apply the four-truth framework, developed by the South African Truth and Reconciliation Commission, to better understand how the High Desert Museum approached the interpretation of Native American content and stories and to explore how …

Investigating The Consequences Of Conjugated And Secreted Isg15 On Coronavirus Pathogenesis, Mudassir Syed Ali

Dissertations

Coronaviruses have evolved a breadth of mechanisms to antagonize host innate immune responses. One widely studied mechanism is the ability to deconjugate ISG15 from target proteins in a process called deISGylation, which is catalyzed by the papain-like protease (PLP) domain of viral non-structural protein (nsp) 3. Since PLP activity is required for viral replication, it has been challenging to generate an infectious virus with a PLP that maintains protease activity but has lost deISGylase activity. In this study, we generated a chimeric MHV-A59 with its PLP2 domain replaced with that of the human coronavirus HKU1, which has been documented to …

Pyruvate Dehydrogenase Kinase 4 Mediates Sex Specific Outcomes In Sepsis Induced Cardiomyopathy, John Yap

Dissertations

During sepsis, males often experience worse cardiac outcomes than females. Here, we identified pyruvate dehydrogenase kinase 4 (PDK4) as a key contributor to this disparity. PDK4 is a mitochondrial protein that regulates glucose utilization by inhibiting pyruvate dehydrogenase (PDH). Using a mouse model of endotoxemia, we induced acute inflammation with a sublethal dose of lipopolysaccharide (LPS), which caused cardiac dysfunction and significantly increased myocardial PDK4 expression in males but not females. Cardiac-specific PDK4 overexpression promoted LPS-induced cardiac dysfunction in both sexes, whereas cardiac-specific PDK4 knockout provided protection. In wild-type males, LPS disrupted cardiac metabolism by decreasing PDH activity and fatty …

Developing Full Performance Interpreters: Cultivating Interdisciplinary Mindsets And Skillsets To Engage Audiences In Climate Change, Women's History, And Other Contested Heritage Topics, Delia A. Lister

Dissertations

Heritage sites immerse visitors in places where the impacts of climate change are readily apparent. They are also powerful places to elevate untold stories of women and girls. Heritage site interpreters interact daily with audiences who bring diverse lived experiences, different levels of subject matter knowledge, and multiple perspectives on climate change and the role of women in history. Every visitor interaction has a set of meanings, values, and narratives that visitors knowingly or unknowingly espouse. To interpret contested heritage topics, such as climate change and women’s history, interpreters must cultivate interdisciplinary mindsets and skillsets. The purpose of this basic …

Social Media And The Effect On Student Engagement, Lara Mcelveen

Dissertations

The purpose of my study was to determine the impact of social media on student engagement and behaviors in high school classrooms. The overarching research question that guided my study was: What is the impact of social media on student engagement? I used a mixed methods approach of quantitative and qualitative data to research my topic. I collected the data using surveys of two stakeholder groups in the study: young adults and educators. The survey results showed that both educators and young adults perceived a decline in class engagement and the rise of behavior in the classroom from social media …

Seen And Heard: A Visual Testimony Of Purity Culture Using Qualitative Photovoice Methodology, Amanda Brown

Dissertations

Purity culture, rooted in Christian teachings, has profoundly shaped individuals’ identities, relationships, and perceptions of sexuality, gender, and faith. While popular culture is talking about the effects of purity culture, scholarly literature is lacking. This study employed photovoice methodology to center the voices of those who grew up in purity culture, using photography and personal narratives to explore its long-term effects. The study focused on how individuals who have experienced purity culture articulate and visualize their stories, revealing nuanced insights across seven thematic domains: gender expectations, romantic relationships, faith, mental health, identity formation, sex and sexuality, and healing and …

Narratives Of Jewish American Public School Educators Amid Rising Antisemitism Post October 7, 2023, Cassandra Schwartz

Dissertations

This study investigated how Jewish American public school educators are responding to rising antisemitism post-October 7, 2023. While research exists on global antisemitism, the experiences of Jewish educators within the unique context of American public schools represent a significant and under-explored gap in academic literature. A qualitative narrative research approach, grounded in critical theory, was employed. Data were collected through semi-structured interviews with eight Jewish American public school educators and analyzed thematically. The findings revealed participants’ experiences of a heightened sense of fear and silence from colleagues and institutions, leading to feelings of isolation and being unsupported. Critically, this study …

Comparative Genotoxicological Analysis Of Occupational Pesticide Exposures: An Experimental Approach And Systematic Review, Moustafa Samy Sherif

Dissertations

This dissertation investigates the genotoxic and cytotoxic effects of pesticide exposure through three complementary research components: a systematic review of occupational pesticide exposure in Arab countries (AraSys), a systematic review on encapsulated versus conventional pesticide formulations (Encap-Sys), and experimental toxicological assessments of various pesticide formulations in human cell lines (Pyr-Ex). This experimental component includes cytotoxicity assays using propidium iodide and DNA damage assessments via alkaline comet assays in HL60 and HepG2 cell lines exposed to pyrethroid insecticides and glyphosate-based formulations.

The AraSys systematic review revealed a critical positive association between occupational pesticide exposure and DNA damage in agricultural workers in …