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Articles 4201 - 4230 of 4613
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Cloning And Characterisation Of Alternansucrase From Leuconostoc Citreum Abk-1 And Role Of Surface Aromatic Acids On Product Size, Karan Wangpaiboon
Cloning And Characterisation Of Alternansucrase From Leuconostoc Citreum Abk-1 And Role Of Surface Aromatic Acids On Product Size, Karan Wangpaiboon
Chulalongkorn University Theses and Dissertations (Chula ETD)
The alternansucrase (ALT, EC 2.4.1.140) catalyses transferring of glucose from sucrose to produce a polymer with α-1,6 and α- 1,3 linkages, so-called "alternan". The ALT-encoding gene from Leuconostoc citreum ABK-1 (WTalt) was successfully cloned and expressed in Escherichia coli BL21 (DE3). The two versions of truncated SH3-like domains, ∆3SHALT and ∆7SHALT, were successfully constructed. The WTALT, ∆3SHALT and ∆7SHALT possessed optimum temperature of 40 °C, while optimum pH of WTALT was at 5.0 but ∆3SHALT's and ∆7SHALT's were shifted to pH 4.0. Their activities could be enhanced by Mn²⁺. Kinetic studies of all ALTs were mainly responsible for transglycosylation activity …
Metal Artifact Reduction In Computed Tomography At Head And Neck Region, Sornjarod Oonsiri
Metal Artifact Reduction In Computed Tomography At Head And Neck Region, Sornjarod Oonsiri
Chulalongkorn University Theses and Dissertations (Chula ETD)
The common streak artifacts in computed tomographic images result from the metal implant in patients. Such the artifacts could suppress proper diagnosis or misdiagnosis in computed tomographic images. The purpose of this study is to develop the method for metal artifact reduction using MATLAB software and implement in both phantom and patients for head and neck computed tomographic imaging. The new algorithm of metal artifact reduction in computed tomographic images had been developed using MATLAB software. The homogeneous phantom, Alderson Rando phantom, and patients with a metal implant in the head and neck region had been scanned by Philips Brilliance …
Pathomechanism Of X-Linked Osteogenesis Imperfecta, Siraprapa Tongkobpetch
Pathomechanism Of X-Linked Osteogenesis Imperfecta, Siraprapa Tongkobpetch
Chulalongkorn University Theses and Dissertations (Chula ETD)
Osteogenesis imperfecta (OI) or brittle bone disease is a genetic disorder characterized by deformities of bones and multiple bone fractures. We identified a new causative gene, MBTPS2, in two unrelated patients with OI inherited in X-linked pattern (X-OI). MBTPS2 or site-2 protease (S2P) is a protease that cleaves the transmembrane proteins to activate them acting as transcription factors. To determine pathomechanism of X-OI caused by MBTPS2 mutations, S2P functions were investigated. RNA and protein of S2P were stable. Instead, the defective S2P decreases its cleavage activities. ATF6 and CREB3L1 are target proteins of S2P. We demonstrated decreased a transcriptional activity …
Intracellular Trafficking Of Different Shaped Oxidized Carbon Nanoparticles, Banphot Jiangchareon
Intracellular Trafficking Of Different Shaped Oxidized Carbon Nanoparticles, Banphot Jiangchareon
Chulalongkorn University Theses and Dissertations (Chula ETD)
Oxidized carbon nanospheres (OCSs) and graphene oxide sheets (GOShs) were prepared by oxidation of graphite. Oxidized carbon nanotubes (OCTs) was synthesized from single-walled carbon nanotubes. All three shapes of oxidized carbon nanoparticles (OCNs) were used for investigation of their intracellular trafficking in human embryonic kidney cells (HEK293T), mouse macrophage cells (RAW264.7) and human liver cancer cells (HepG2). The results revealed all three shapes of OCNs were internalized into through HEK293T and RAW264.7 cells without endosomal trapping, including localization of all the three OCNs in HEK293T's lysosome. In case of RAW264.7 cells, OCTs and GOShs were localized in lysosomes, only OCSs …
Legal Measures For Employer To Reach Fair Practice In Organizational Restructuring In Thailand, Pitsanuchai Thongtha
Legal Measures For Employer To Reach Fair Practice In Organizational Restructuring In Thailand, Pitsanuchai Thongtha
Chulalongkorn University Theses and Dissertations (Chula ETD)
Restructuring, a normal managerial task of entrepreneurship, can lift up an enterprises' competitiveness potential in business societies. Restructuring will affect to the rights of all people in the enterprise. Labor laws and regulations not only provide adequate protection for employees, but also promote the flexibility to the business sectors. The employment relationships are involved with the actions of three parties - employees, employers and the government - that must substantially cooperate in order to establish efficient labor regulations. Thai labor laws which relate to working condition adjustment and dismissal are obsolete. It provides too much power for the courts in …
Characteristics And Catalytic Properties Of Agli/Sio2 Catalysts On Different Silica Supports For Oxidative Dehydrogenation Of Ethanol To Acetaldehyde, Narawich Mukda
Chulalongkorn University Theses and Dissertations (Chula ETD)
This work focuses on investigation of the oxidative dehydrogenation and non-oxidative dehydrogenation of ethanol over AgLi/SiO2 catalysts to produce acetaldehyde by having three different types of silica support, spherical silica particle (small particle size; SPS), medium silica particle size (MPS), and large silica particle size (LPS). The spherical silica particle (SSP) was synthesized using the sol-gel method, whereas SiO2 (MPS) and SiO2 (LPS) were obtained from commercial suppliers. AgLi/SiO2 catalysts were prepared by incipient wetness co-impregnation method. The physicochemical properties of catalysts were analyzed by using several technique such as X-ray diffraction (XRD), N2-physisorption, SEM-EDX, UV-visible spectroscopy, H2-TPR. Moreover, the …
The Effect Of Adsorption On Photocatalytic Degradation Of Phenyl Urea Herbicides On Zinc Oxide, Sutaporn Meephon
The Effect Of Adsorption On Photocatalytic Degradation Of Phenyl Urea Herbicides On Zinc Oxide, Sutaporn Meephon
Chulalongkorn University Theses and Dissertations (Chula ETD)
The effect of adsorption on photocatalytic degradation was studied by using zinc oxide with different morphologies and exposed surfaces as the photocatalyst. Polar zinc-terminated surface and polar oxygen-terminated surface are dominating planes on the top and bottom of a crystal of ZnO conventional particles, while non-polar surface is the main plane on the side of ZnO nanorods. These surfaces affect the adsorption behavior of phenylurea herbicides, i.e. diuron, linuron and 3,4-dichloroaniline. Consequently, they cause the difference in photocatalytic degradation rate and intermediate products formed during the degradation. The adsorption capacity of ZnO conventional particles is about twice as high as …
Synthesis And Optical Properties Of Pyrrolidinyl Peptide Nucleic Acid Carrying Fluorescence Nucleobases, Duangrat Nim-Anussornkul
Synthesis And Optical Properties Of Pyrrolidinyl Peptide Nucleic Acid Carrying Fluorescence Nucleobases, Duangrat Nim-Anussornkul
Chulalongkorn University Theses and Dissertations (Chula ETD)
Pyrrolidinyl peptide nucleic acid bearing D-prolyl-2-aminocyclopentanecarboxylic acid backbone (acpcPNA) is a nucleic acid mimic that shows superior binding affinity, stability and specificity to complementary DNA than the original PNA. This research focuses on the development of hybridization responsive fluorescence acpcPNA probes bearing fluorescent nucleobases that exhibit fluorescence increase upon hybridization to a specific nucleobase in the DNA target. The acpcPNA carrying the fluorescent nucleobases were synthesized via two different approaches, namely 1) pre-synthesized fluorescence PNA monomer as a building block that was subsequently incorporated into the PNA by solid phase synthesis and 2) post-synthetic modification of acpcPNA carrying a reactive …
Ferrocene-Bearing Tea Polyphenol Particles As Anticancer Drug Carriers, Punnawich Phaiyarin
Ferrocene-Bearing Tea Polyphenol Particles As Anticancer Drug Carriers, Punnawich Phaiyarin
Chulalongkorn University Theses and Dissertations (Chula ETD)
Ferrocene is a redox moiety that can be positively charged upon being oxidized. Thus, it is possible to use this moiety to make a polymer platform that is redox responsive regarding their water solubility. Here we prepared polymerized EGCG nanoparticles (pEGCG) and polymerized EGCG gum (pEGCG-gum) from tea polyphenol EGCG. Ferrocene was grafted onto the polymerized tea polyphenol and the obtained polymers were allowed to self-assemble into water-insoluble and indispersible sub-micron particles. The water-insoluble ferrocene-bearing particles became water-dispersible particles with nanometer sizes upon being oxidized by hydrogen peroxide. The oxidized particles, Fc-pEG-gum can inhibit growth of HepG2 liver cancer cells …
Factors Affecting Building Damage And People's Preparedness For Earthquake In Chiang Rai, Narongdej Intaratchaiyakit
Factors Affecting Building Damage And People's Preparedness For Earthquake In Chiang Rai, Narongdej Intaratchaiyakit
Chulalongkorn University Theses and Dissertations (Chula ETD)
On May 5, 2014, an earthquake with a magnitude of 6.3 on the Richter scale occurred in Chiang Rai, Thailand. This earthquake was the strongest earthquake in Thailand at the Mae Lao District region. It also caused building damage and casualties. In this research, 277 participants living in village no.2 and village no.7 of Dong Mada, a sub-district at Mae Lao district in Chiang Rai, were selected. A questionnaire was used to interview these participants, and the data were analyzed by Chi-square, Fisher's exact test, a Mann-Whitney U test, and a Kruskal-Wallis test. The objective of this study was to …
Contact Problems With Surface Stress Effects, Supakorn Tirapat
Contact Problems With Surface Stress Effects, Supakorn Tirapat
Chulalongkorn University Theses and Dissertations (Chula ETD)
This dissertation presents a theoretical study of contact problems with consideration of surface energy effects by adopting a complete Gurtin-Murdoch theory of surface elasticity. The fundamental solution of a layered elastic half-space subjected to axisymmetric surface loading is obtained by using Love's representation and the Hankel integral transform. The analytical solutions for both displacement and stress fields are expressed in terms of semi-infinite integrals, which can be accurately evaluated by employing a numerical quadrature scheme. The obtained solutions are employed as the required influence functions in the investigation of axisymmetric indentation on a layered elastic medium with frictionless and adhesive …
Mechanisms Of Thai Medicinal Plant Extracts On The Attenuation Of Glutamate-Mediated Neurotoxicity, Anchalee Prasansuklab
Mechanisms Of Thai Medicinal Plant Extracts On The Attenuation Of Glutamate-Mediated Neurotoxicity, Anchalee Prasansuklab
Chulalongkorn University Theses and Dissertations (Chula ETD)
As the world population ages, neurodegenerative diseases, particularly Alzheimer's disease, are becoming a major public health concern with increasing incidence and prevalence worldwide while no cure currently exists. To challenge this situation, herbal medicine may provide a potential alternative treatment as use of natural-derived substances has been proven to be effective in the prevention and/or treatment of several diseases. During the past decades, increasing evidence has implicated excessive glutamate levels in the pathway of neuronal cell death. Thailand is a place known for cultivating a variety of tropical plants and herbs, so far many of them have never been examined …
Developing An Area Classification System From Mobile Phone Usage Data, Naruethai Thongphasook
Developing An Area Classification System From Mobile Phone Usage Data, Naruethai Thongphasook
Chulalongkorn University Theses and Dissertations (Chula ETD)
Since human activities are vary by time and place, there have been many attempts to extract social behavior in spatial studies which included area use in the city. This information helps gaining advantages in city and facilities planning. Nowadays, many people carry mobile phone with them for communication purpose. This motivates us to analyze mobile phone usage in different area types. This thesis proposes method of an analysis for area use classification from mobile phone usage pattern. CDR data was used to define mobile phone usage pattern by hour from 1:00 to 24:00 and day of week from Monday to …
Automatic 3d Hair Model From Small Set Of Images, Nuttapon Vanakittistien
Automatic 3d Hair Model From Small Set Of Images, Nuttapon Vanakittistien
Chulalongkorn University Theses and Dissertations (Chula ETD)
We present a system for creating hair model that matches a user's hairstyle from images. The model consists of guide hair strands and can be used in a real-time hair simulator. Our goal differs from most previous work which aims to create realistic high resolution hair for off-line applications or create mesh of the exterior of the hair volume for image manipulation. Our primary aim is for user to be able to put his/her hairstyle into game or other real-time applications. By taking photos in 8 views of the user's head using a smart phone camera and segmenting images with …
Efficient And Robust Grasp Planning Based On Independent Contact Region And Caging, Teesit Makapunyo
Efficient And Robust Grasp Planning Based On Independent Contact Region And Caging, Teesit Makapunyo
Chulalongkorn University Theses and Dissertations (Chula ETD)
A conventional way to find a proper grasp to grab and hold any object is to measure its stability which usually is based on physical constraint called force-closure. This execution works well from the theoretical point of view but often fails on an actual robot due to many reasons such as intrinsic errors in robot's system and a disparity between real and simulated physics. Several research works introduced methods to alleviate those issues and increase the success rate of grasping for a real robot. Caging and Independent Contact Region are ones of them. In this work, we investigate a method …
High Capacity Image Steganography Tolerating Image Compression, Eittipat Kraichingrith
High Capacity Image Steganography Tolerating Image Compression, Eittipat Kraichingrith
Chulalongkorn University Theses and Dissertations (Chula ETD)
Nowadays, data privacy becomes more important. Most of the existing data protection schemes based on cryptography cannot hide the existence of secret data. Thus, a steganography approach plays an important role to handle this problem. Image steganography can be categorized into two methods which are baesd on spatial domain and transform domain. Methods using spatial domain have high embedding capacity but they are not robust to image compression. On the other hand, methods using transform domain usually work with image compression but have low embedding capacity. In recent image steganography research, many transform domain methods are based on JPEG format …
Biological-Like Memory Allocation Scheme Simulation, Gasydech Lergchinnaboot
Biological-Like Memory Allocation Scheme Simulation, Gasydech Lergchinnaboot
Chulalongkorn University Theses and Dissertations (Chula ETD)
When Gordon Moore observed the number of transistor increasing pattern while memory bandwidth could not catch up with processing unit performance, this diverging rate kept stretching out to create what eventually transpired to be Memory Wall. This consequence becomes a major performance bottleneck. Many bottleneck elimination approaches have been attempted. They incorporate considerable overhead and high complexity. This research proposes a novel memory allocation scheme that employs biological behavioral principles of the living creatures. At the principal construct of their life form lives the cells having limited resources, yet passively operates with little overhead. The proposed method imitates this unicellular …
Diagnosis Of Heart Disease Using Mixed Classifier, Sarawut Meesri
Diagnosis Of Heart Disease Using Mixed Classifier, Sarawut Meesri
Chulalongkorn University Theses and Dissertations (Chula ETD)
At present, there are many studies related to the use of medical information, in order to assist in the analysis and diagnosis of the patients. In the field of computer science, there are methods to assist in analysis and diagnosis of the various diseases using the data mining techniques. Data mining is a popular technique used for analyzing a large number of data, to find the relationship of the hidden information in those data and applied for the benefits of the organization. Classification technique based on the supervised learning is one of the data mining techniques, which divides the dataset …
Energy Aware Scheduling For Heterogeneous Mobile Task Computing, Vittayasak Rujivorakul
Energy Aware Scheduling For Heterogeneous Mobile Task Computing, Vittayasak Rujivorakul
Chulalongkorn University Theses and Dissertations (Chula ETD)
The problem of scheduling a set of dependent tasks from a user mobile device to several servers in communication cells while the user is moving along these cell in various speed is studied in this thesis. The challenging issue is the execution speed of each server and the speed of user's movement are not compatible. This leads to the difficulty of assigning and finishing the subset of scheduled dependent tasks to each server within the limitation of execution time during passing a cell. Another concern involved this study is the constraints on the length of makespan in terms of minimum …
Development Of An Instructional Model Integrating Webquest Learning Approach And Reflective Practice To Enhance English Critical Reading Ability Of Undergraduate Students In Cambodia, Chanchhaya Chhouk
Chulalongkorn University Theses and Dissertations (Chula ETD)
The purposes of this study were 1) to develop an instructional model integrating WebQuest Learning Approach and Reflective Practice to enhance English critical reading ability of undergraduate students, 2) to investigate the effectiveness of the instructional, and 3) to investigate undergraduate students' English critical reading ability development learning with the instructional model. The research and development processes were divided into four phases: 1) studying of the significance of the problem and learning approaches, 2) developing of the instructional model integrating WebQuest Learning Approach and Reflective Practice, 3) Studying the effectiveness of the instructional model integrating WebQuest Learning Approach and Reflective …
Socioeconomic Determinants Of Happiness Of The Elderly In Bhutan, Tashi Duba
Socioeconomic Determinants Of Happiness Of The Elderly In Bhutan, Tashi Duba
Chulalongkorn University Theses and Dissertations (Chula ETD)
Elderly in Bhutan are rising steadily as a proportion of total population. In 2015, population older than 60 constituted about 7.3% of the total population compared to 6.9% in 2010. By 2030, the elderly population is estimated to reach 10.1% of total population. Along with growing numbers of elderly in Bhutan and rapid socioeconomic transformations, the individual-level of happiness decreases with age, the lowest being among the elderly (the Gross National Happiness Index surveys of 2010 and 2015 and Bhutan Living Standard Survey 2012). Nevertheless, there is limited literature exploring factors that are associated with happiness of the elderly. This …
Tobacco Use, Health Care Utilization, Household Expenditure And Smoking Cessation In China, Changle Li
Tobacco Use, Health Care Utilization, Household Expenditure And Smoking Cessation In China, Changle Li
Chulalongkorn University Theses and Dissertations (Chula ETD)
This dissertation studied the tobacco use impact of on health care utilization, household expenditure, and self-rated health among rural residents in rural China. The 2010-2014 China Family Panel Studies data were employed here. Moreover, this study also conducted the randomized controlled trial and analyzed the cost-effectiveness smoking cessation intervention among college-aged smokers in Inner Mongolia, China. The main findings showed: (1) Current and former smokers use more outpatient care than non-smokers. Moreover, former smokers use more inpatient care than non-smokers in rural China. (2) Long-term quitters decreased the probability of using inpatient care compared with recent and moderate-term quitters in …
Asset Pricing And Network Topology, Harnchai Eng-Uthaiwat
Asset Pricing And Network Topology, Harnchai Eng-Uthaiwat
Chulalongkorn University Theses and Dissertations (Chula ETD)
This dissertation provides new empirical evidence for the relationship between network structure and asset returns in US, international markets, and Thailand. Previous studies find that a network of return correlations provides the meaningful economic taxonomy of the equity market. This finding makes the network structure a suitable channel through which an idiosyncratic shock propagates. This network feature can eliminate or amplify the idiosyncratic shock on the system-wide level. Therefore, the diversifying argument of the capital asset pricing models is not always true as the idiosyncratic shock becomes more significant when interacting with the network measures. Based on this idiosyncratic shock …
Optimal Sizing, Siting, And Scheduling Of Bess For Mitigatingvoltage Problem In Distribution Utilities With Highpenetration Of Pv Rooftops, Anh Thi Nguyen
Optimal Sizing, Siting, And Scheduling Of Bess For Mitigatingvoltage Problem In Distribution Utilities With Highpenetration Of Pv Rooftops, Anh Thi Nguyen
Chulalongkorn University Theses and Dissertations (Chula ETD)
For ambition of reducing CO2 emission and reliance on fossil fuels, solar power generation has been received special supports and deployed rapidly in many distribution networks. However, with a high presence of solar power generation, power grid control is no longer simple as conventional one due to natural variation of solar power and large space dispersion of solar power systems. The negative impacts comprise power system stability, electric power quality involving frequency and voltage criteria and other potential issues. Among these impacts, voltage problem is most obvious. Many solutions have been proposed to solve the voltage problem whereas battery energy …
A Ubiquitous Mooc Instructional Design Model Based On Cognitive Dissonance For Enhancing Higher Education Students' Cross-Cultural Competence, Boonrat Plangsorn
A Ubiquitous Mooc Instructional Design Model Based On Cognitive Dissonance For Enhancing Higher Education Students' Cross-Cultural Competence, Boonrat Plangsorn
Chulalongkorn University Theses and Dissertations (Chula ETD)
The research objectives of this study were (1) to study undergraduate students' opinions in designing a ubiquitous MOOC, (2) to develop a ubiquitous MOOC instructional design model based on cognitive dissonance for enhancing higher education student's cross-cultural competence (U-MOOC model), and (3) to study the effects of a ubiquitous MOOC instructional design model based on cognitive dissonance for enhancing higher education student's cross-cultural competence. This study used the research and development research methodology divided into three phases: survey research, U-MOOC model development, and experimental research. The samples of survey phase were 410 undergraduate students recruited from eight government universities. The …
Education Management Reform Strategies For Enhancing The Quality Citizenship In Cambodia, Chuonnaron Hang
Education Management Reform Strategies For Enhancing The Quality Citizenship In Cambodia, Chuonnaron Hang
Chulalongkorn University Theses and Dissertations (Chula ETD)
This research study aimed to 1) study the conceptual framework of education management reform and the quality citizenship; 2) study the current and desirable state of education management reform for enhancing the quality citizenship in Cambodia; 3) find out the needs in education management reform for enhancing the quality citizenship in Cambodia; 4) develop education management reform strategies for enhancing the quality citizenship in Cambodia. This study employed the research and development method (R&D). The data were collected from 710 respondents, consisting of 10 education policymakers, 30 Directors of MoEYS departments, 80 school administrators, 150 teachers, 80 School Support Committee …
Multiple Face Detection And Recognition On Embedded Computer Vision System, Savath Saypadith
Multiple Face Detection And Recognition On Embedded Computer Vision System, Savath Saypadith
Chulalongkorn University Theses and Dissertations (Chula ETD)
Face recognition is widely used in many applications such as biometric for authentication, surveillance system, user-identification, and personalized technology. The state-of-the-art algorithm based on Convolutional Neural Network (CNN) can achieve up to 99% of recognition accuracy. However, there is a limitation to implement the CNN based technique into embedded system to recognize multiple face in real-time as it requires extensive computation. In this thesis, we propose a framework for multiple face recognition which consists of face detection algorithm, face recognition, and tracking. Our face recognition algorithm based on state of the art deep CNN with small computational parameters. The tracking …
Molecular Beam Epitaxial Growth Of Gasb And Insb Nanostructures On (001) Ge Substrates, Zon -
Molecular Beam Epitaxial Growth Of Gasb And Insb Nanostructures On (001) Ge Substrates, Zon -
Chulalongkorn University Theses and Dissertations (Chula ETD)
The self-assembled GaSb and InSb nanostructures (quantum dots, QDs) are grown on (001) Ge substrates in Stranski-Krastanow growth mode by molecular beam epitaxy. The structural properties are characterized by ex situ atomic force microscopy (AFM), and the related optical properties are observed by photoluminescence (PL) spectroscopy. Growing of polar GaAs on non-polar Ge creates anti-phase domains (APDs). By careful controlling of growth, APDs surface becomes flat and having large surface area (~µm2) which is sufficient to form QD array in each domain. The effects of APDs on the formation of QDs are discussed. By varying the growth conditions, different QD …
Establishing A Luggage Handling Service Company, Anan Prasertrungreung
Establishing A Luggage Handling Service Company, Anan Prasertrungreung
Chulalongkorn University Theses and Dissertations (Chula ETD)
Luggage delivery service has never existed in Thailand officially but already established in another country such as Japan. However, this service has a potential to be a very good service as it could benefit to traveler which Thailand has welcomed more than 30m of them per annum but the model from another country could not be implement directly to Thailand. By developing the model, this service will fit to Thai's market. There are many risks that researcher has to consider before starting the business to avoid or prevent risks into the business. Moreover, this study will not limit only the …
Logistics Business Process Improvement In A Sport Gear Company, Azadeh Kamyabi
Logistics Business Process Improvement In A Sport Gear Company, Azadeh Kamyabi
Chulalongkorn University Theses and Dissertations (Chula ETD)
A small sports gear company, specialising in boxing and muaythai, is receiving complaints from customers due to incorrect shipments. The consequences of incorrect shipments are: customer dissatisfaction, higher costs due to returns and reshipments, and waste of time and resources. As a result, the objective of this thesis is to reduce incorrect shipments improving the internal logistics processes using framework of SCOR model and information technology management. Having investigated the record of each incorrect shipment, a working group of employees was formed to analyse and determine possible causes using quality improving tools such as fishbone diagram and why-why analysis. Each …