Digital Commons Network^™

Do Organic Cherry Vine Tomatoes Taste Better Than Conventional Cherry Vine Tomatoes? A Sensory And Instrumental Comparative Study From Ireland, Clare Gilsenan, Roisin Burke, Catherine Barry-Ryan

Articles

A consumer panel was able to distinguish a perceptible difference between organically farmed and conventionally produced tomatoes, and preferred the taste of the conventional tomatoes. The sensory evaluation results of the trained panel revealed that the conventional tomatoes were sweeter and less sour than the organic tomatoes. In addition to this, the conventional tomatoes showed significant differences for ^oBrix, reducing sugars and electrical conductivity. No significant differences were observed between the organic and conventional tomato samples for color, size, firmness, pH and dry matter values.

Regulatory Contrarians, Brett Mcdonnell, Daniel Schwarcz

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This Article explores the role that “regulatory contrarians” can play in promoting more adaptive financial regulation. Such contrarians have several distinguishing features. First, they possess persuasive authority by virtue of their position, access to media and officials, or speaking engagements and reports. Second, they are affiliated with, and enjoy privileged access to, a regulatory entity but are nonetheless independent, as reflected in their budget, staffing, and/or priorities. Finally, they are tasked with studying the regulatory process, policy positions, and the regulated market and in some way reporting on deficiencies and potential improvements. The Article argues that regulatory contrarians can modestly …

An Economic Analysis Of Patent Law's Inequitable Conduct Doctrine, Thomas F. Cotter

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In recent years, patent law’s inequitable conduct doctrine has attracted considerable attention from judges, legislators, patent lawyers, and commentators, culminating most recently in the Federal Circuit’s decision to revise certain aspects of the doctrine in its en banc decision in Therasense, Inc. v. Becton, Dickinson & Co. Building on the work of other scholars, this Article proposes an instrumental view of the doctrine as, ideally, a tool for inducing patent applicants to disclose the optimal quantity of information relating to the patentability of their inventions; it then presents a formal model of the applicant’s choices in deciding how much information …

L-Arginine Is Essential For Pancreatic B-Cell Functional Integrity, Metabolism And Defense From Inflammatory Challenge, Mauricio S. Krause, Neville H. Mcclenaghan, Peter R. Flatt, Paulo I Homem De Bittencourt, Colin Murphy, Philip Newsholme

Articles

In this work, our aim was to determine whether L-arginine (a known insulinotropic amino acid) can promote a shift of b-cell intermediary metabolism favoring glutathione (GSH) and glutathione disulfide (GSSG) antioxidant responses, stimulus–secretion coupling and functional integrity. Clonal BRIN-BD11 b-cells and mouse islets were cultured for 24 h at various L-arginine concentrations (0–1.15 mmol/l) in the absence or presence of a proinflammatory cytokine cocktail (interleukin 1b, tumour necrosis factor a and interferon g). Cells were assessed for viability, insulin secretion, GSH, GSSG, glutamate, nitric oxide (NO), superoxide, urea, lactate and for the consumption of glucose and glutamine. Protein levels of …

Synthesis, Co-Polymerisation And Electrochemical Evaluation Of Novel Ferrocene-Pyrrole Derivatives, Mary Deasy, Eithne Dempsey, Geok Hong Soon, Oliver Worsfold

Articles

New ferrocene derivatives, ((4-(1H-pyrrol-1-yl)phenoxy)carbonyl) ferrocene (4) and (6-(4-(1H-pyrrol-1-yl)phenoxy)hexyl) ferrocene (7) were synthesised, characterised and electrochemically evaluated as redox active films formed via anodic oxidation with pyrrole. Thin film studies were conducted and films formed from both compounds resulted in a stable Fe ^II/III redox couple with E^o = 0.04V and 0.36V vs. Ag/Ag⁺ for (7) and (4) respectively. Both potential sweeping and chronocoulometry were employed for film formation with the former resulting in controllable, reproducible film deposition. Growth conditions and solution concentrations were varied in the case of both compounds in order to assess …

O My Sons And Daughters, How Do I Immiserate Thee: Let Me Count The Ways, Kenneth M. Casebeer

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No abstract provided.

Consultation And Legitimacy In Transnational Standard-Setting, Caroline Bradley

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No abstract provided.

Lies, Damned Lies, And Judicial Empathy, Mary Anne Franks

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No abstract provided.

Unwilling Avatars: Idealism And Discrimination In Cyberspace, Mary Anne Franks

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No abstract provided.

Taking The Business Out Of Work Product, Michele M. Destefano Beardslee

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Over the past fifteen years, a common set of questions has surfaced in different areas of scholarship about the breadth of the corporate attorney's role: Should the corporate attorney provide business advice when providing legal advice? Should the corporate attorney provide counsel related to other disciplines such as public relations, social responsibility, morals, accounting, and/or investment banking? Should the corporate attorney prevent corporate wrongdoing? Questions like these resound in the scholarship addressing the risks and benefits of multi-disciplinary partnerships, gatekeeping, moral counseling, ancillary services, and the application of the attorney-client privilege. When looked at in combination, these segregated discussions equate …

Nonparticipatory Association And Compelled Political Speech: Consent As A Constitutional Principle In The Wake Of Citizens United , Frances R. Hill

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No abstract provided.

Plan B For Campaign-Finance Reform: Can The Fcc Help Save American Politics After Citizens United?, Lili Levi

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No abstract provided.

Holden Caulfield Grows Up: Salinger V. Colting, The Promotion-Of-Progress Requirement, And Market Failure In A Derivative-Works Regime, John M. Newman

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In 2009, the pseudonymous 'John David California" announced plans for U.S. publication of 6o Years Later: Coming Through the Rye, a "sequel" to JD. Salinger's canonical novel The Catcher in the Rye. Salinger reacted swiftly, bringing a copyright infingement suit to enjoin publication of the new work. The district court granted the injunction, effectively banning U.S. distribution of the sequel and unintentionally illustrating modern copyright law's troubling divergence from the purpose of the constitutional grant of copyright authority to Congress.

Economic analysis demonstrates the tension caused by the repeated, incremental expansion of copyright protections-at some point, the Copyright Act will …

Enabling Refugee And Idp Law And Policy: Implications Of The U.N. Convention On The Rights Of Persons With Disabilities, Professor Michael Stein, Janet E. Lord

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No abstract provided.

What If Daniel Ellsberg Hadn't Bothered?, Heidi Kitrosser

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This article was written for the Indiana Law Review’s 2011 annual symposium entitled, “What If? Counterfactuals in Constitutional History.” As the article’s title suggests, it considers the impact of Daniel Ellsberg’s decision to leak the Pentagon Papers to the New York Times. The article takes some liberty with the topic of constitutional counterfactuals. Despite its author’s vast enjoyment of several classic movies and television episodes featuring parallel worlds, the article does not build a counterfactual universe in which Daniel Ellsberg never leaked the Pentagon Papers. It hints at such a world indirectly, however, by considering the difference that Ellsberg’s leak …

Growth Inhibition Of Common Food Spoilage And Pathogenic Microorganisms In The Presence Of Brown Seaweed Extracts, Shilpi Gupta, Sabrina Cox, Gaurav Rajauria, Amit Jaiswal, Nissreen Abu-Ghannam

Articles

The possibility of using extracts from brown seaweed, Himanthalia elongata, as a natural antimicrobial agent for food preservation is presented. The effect of different concentrations of seaweed extract on the growth kinetics of four common food spoilage (Pseudomonas aeruginosa and Enterococcus faecalis) and food pathogenic micro-organisms (Listeria monocytogenes and Salmonella abony) was examined. Seaweed extract at a concentration of 6% inhibited the growth of all four of the studied organisms. Lower concentrations of seaweed extract prolonged the lag phase and reduced both the exponential growth rate and final population densities of the culture. Suitability of three kinetic models, Baranyi-Roberts, Modified …

A Comparative Examination Of The Nature Of Change In Macroeconomic Policies, John Hogan

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This article examines the impact of economic crises on macroeconomic policies in Ireland in the late 1950s and Sweden in the early 1980s, framed within the context of the policy change literature. Each of these countries‟ responses to the crises affecting them, tempered as they were by historical and political factors, provides valuable insights into their political economies. These findings enable us to compare and contrast the nature of each crisis and the policy responses adopted. The value of such comparison is in the perspective it offers, contributing to the goal of building a body of increasingly complete explanatory theory …

Mobile Visibility Querying For Lbs, James Carswell, Keith Gardiner, Junjun Jin

Articles

This article describes research carried out in the area of mobile spatial interaction (MSI) and the development of a 3D mobile version of a 2D web-based directional query processor. The TellMe application integrates location (from GPS, GSM, WiFi) and orientation (from magnetometer/accelerometer) sensor technologies into an enhanced spatial query processing module capable of exploiting a mobile device’s position and orientation for querying real-world spatial datasets. This article outlines our technique for combining these technologies and the architecture needed to deploy them on a sensor enabled smartphone (i.e. Nokia Navigator 6210). With all these sensor technologies now available on off-the-shelf devices, …

Anticancer And Antifungal Activity Of Copper(Ii) Complexes Of Quinolin-2(1h)-One-Derived Schiff Bases, Bernadette S. Creaven, Brian Duff, Denise A. Egan, Kevin Kavanagh, Georgina Rosair, Venkat Reddy Thangella, Maureen Walsh

Articles

The condensation of substituted aromatic aldehydes with 7-amino-4-methyl-quinolin-2(1H)-one (1) has lead to the isolation of quinolin-2(1H)-one derived Schiff bases (2–14). The copper(II) complexes (2a–14a) of the ligands were also prepared, and together with their corresponding free ligands were fully characterised by elemental analyses, spectral methods (IR, ¹H and ¹³C NMR, AAS, UV–Vis), magnetic and conductance measurements. The bidentate ligands coordinated to the copper(II) ion through the deprotonated phenolic oxygen and the azomethine nitrogen of the ligands in almost all cases. X-ray crystal structures of two of the complexes, 5a and 8a, confirmed the bidentate …

Virulence Of An Emerging Respiratory Pathogen, Genus Pandoraea, In Vivo And Its Interactions With Lung Epithelial Cells, Gillian Herbert, Anne Costello, Lydia Fabunmi, Kirsten Schaffer, Kevin Kavanagh, Emma M. Caraher, Máire Callaghan, Siobhan Mcclean

Articles

Pandoraea species have emerged as opportunistic pathogens among cystic fibrosis (CF) and non-CF patients. Pandoraea pulmonicola is the predominant Pandoraea species among Irish CF patients. The objective of this study was to investigate the pathogenicity and potential mechanisms of virulence of Irish P. pulmonicola isolates and strains from other Pandoraea species. Three patients from whom the P. pulmonicola isolates were isolated have since died. The in vivo virulence of these and other Pandoraea strains was examined by determining the ability to kill Galleria mellonella larvae. The P. pulmonicola strains generally were the most virulent of the species tested, with three …

Reporting The Rhetoric, Implementation Of The United Nations Convention On The Rights Of The Child As Represented In Ireland's Second Report To The Un Committee On The Rights Of The Child: A Critical Discourse Analysis, Rachel Kiersey, Noirin Hayes

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Ireland’s second periodic report to the United Nations Committee on the Rights of the Child (CRC) presents the government’s case that it is succeeding in protecting and promoting the rights of all children in Ireland. This article presents a critical discourse analysis of the governments Report to the CRC. Using a refined critical discourse analysis (CDA) model, based on the framework proposed by Chouliaraki & Fairclough (1999); the linguistic structure of the Report is examined alongside consideration of the wider socio-political context in which it exists. The Report is itself a promotional genre . It lists legislative change, strategy plans …

Mapping The Literature Of Health Education: 2006–2008, Amber T. Burtis, Mary K. Taylor

Articles

Objectives:

The study updates Schloman's 1997 study, “Mapping the Literature of Health Education.” The authors identify an updated list of core health education journals and determine the coverage of these journals by electronic indexes.

Methods:

Citations from four source journals for the years 2006 to 2008 were analyzed using the established methodology of the “Mapping the Literature of Allied Health Project.” The cited journals were divided into three zones of productivity by using Bradford's Law of Scattering.

Results:

There were 19,907 citations in 602 source articles. Journal articles were the most commonly cited format type. Of the 1,896 journal titles …

What Is A Professional Cataloger? Perception Differences Between Professionals And Paraprofessionals, Elizabeth J. Cox, Ann K.D. Myers

Articles

This paper examines the roles of professional and paraprofessional catalogers as they are perceived within the cataloging community. A survey was sent to all catalogers in member libraries of the Association of Research Libraries. In presenting these results, the authors consider whether a difference still exists between professional and paraprofessional catalogers beyond the master of library and information science degree and, if so, the nature of any such difference. In the process, the authors also examine issues such as whether catalogers feel that their work is valued and how cataloging work is evaluated.

Advocacy In The Court Of Public Opinion, Installment Two: How Far Should Corporate Attorneys Go, Michele M. Destefano

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Today, legal controversies are tried in the court of public opinion as much as in any court of law. Corporate lawyers' traditional tendency, however, has been to attempt to isolate legal activities from public relations activities. Accordingly, when providing legal advice, they have viewed media considerations as separate. Historically corporate counsels' typical media strategy often consisted of no more than, "no comment." Given today's saturated media culture, this is no longer a viable strategy. Indeed, it appears that some corporate lawyers are adapting to the new media environment and attempting to help their clients manage the public relations impact of …

The First Amendment Degraded: Milkovich V. Lorain And A Continuing Sense Of Loss On Its 20th Birthday, Richard H. Weisberg

Articles

The article critiques the Supreme Court's decision in Milkovich v. Alabama, arguing that it undermines First Amendment protections by narrowing the distinction between fact and opinion in defamation cases. The Court's ruling, led by Chief Justice Rehnquist, held that statements implying false facts are actionable, even if framed as opinions. This decision, the article contends, reverses the constitutional logic of earlier precedents like New York Times Co. v. Sullivan, which trusted audiences to discern fact from opinion. The article warns that Milkovich erodes the First Amendment's faith in audience discernment, fostering a paternalistic judicial approach that stifles public debate.

Determination Of Threshold Exposure And Intensity For Recording Holograms In Thick Green-Sensitive Acrylamide-Based Photopolymer, Mohammad Sultan Mahmud, Izabela Naydenova, Tzwetanka Bebeva, Raghavendra Jallapuram, Suzanne Martin, Vincent Toal

Articles

For optical data storage applications, it is essential to determine the lowest intensity (also known as threshold intensity) below or at which no data page or grating can be recorded in the photosensitive material, as this in turn determines the data capacity of the material. Here, experiments were carried out to determine the threshold intensity below which the formation of a simple hologram—a holographic diffraction grating in a green-sensitized acrylamide-based photopolymer—is not possible. Two main parameters of the recording layers—dye concentration and thickness—were varied to study the influence of the density of the generated free radicals on the holographic properties …

Intracellular Localisation, Geno- And Cytotoxic Response Of Poly N-Isopropylacrylamide (Pnipam) Nanoparticles To Human Keratinocyte (Hacat) And Colon Cells (Sw 480), Pratap Naha, Kunal Bhattacharya, Tiziana Tenuta, Kenneth Dawson, Iseult Lynch, Amaya Gracia, Fiona Lyng, Hugh Byrne

Articles

PNIPAM nanoparticles, with and without a covalentlylinked fluorescent label, were prepared by a free radical polymerisation technique. The cyto and genotoxicity of PNIPAM nanoparticles were analysed in two representative mammalian cell lines, SW480, a colon, and HaCaT, a dermal cell line. Physical characterisation in terms of particle size and zeta potential of the PNIPAM nanoparticles was carried out both in aqueous solution and in the appropriate cell culture media. Uptake and colocalisation of fluorescently labelled PNIPAM nanoparticles was monitored in both cell lines using confocal laser scanning microscopy. Genotoxicity analysis using the Comet assay was performed in both cell lines …

Michelot Yogogombaye V. Republic Of Senegal, Charles C. Jalloh

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No abstract provided.

3dq: Threat Dome Visibility Querying On Mobile Devices, James Carswell, Keith Gardiner, Junjun Yin

Articles

3DQ (Three Dimensional Query) is our mobile spatial interaction (MSI) prototype for location and orientation aware mobile devices (i.e. today's sensor enabled smartphones). The prototype tailors a military style threat dome query calculation using MSI with hidden query removal functionality for reducing “information overload” on these off-the-shelf devices. The effect gives a more accurate and expected query result for Location-Based Services (LBS) applications by returning information on only those objects visible within a user’s 3D field-of-view. Our standardised XML based request/response design enables any mobile device, regardless of operating system and/or programming language, to access the 3DQ web-service interfaces.

Mechanistic Studies Of In Vitro Cytotoxicity Of Poly(Amidoamine) Dendrimers In Mammalian Cells, Sourav Prasanna Mukherjee, Fiona Lyng, Amaya Garcia, Maria Davoren, Hugh Byrne

Articles

Poly(amidoamine) (PAMAM) dendrimer nanoparticles have been demonstrated to elicit a well defined cytotoxicological response from mammalian cell lines, the response increasing systematically with dendrimer generation and number of surface amino groups. In this work, using generation G4, G5, and G6 dendrimers, this systematic response is furthermore demonstrated for the generation of reactive oxygen species, lysosomal activity, and the onset of apoptosis and levels of DNA damage. The results are consistent with a pathway of localisation of PAMAM dendrimers in the mitochondria leading to ROS production causing oxidative stress, apoptosis and DNA damage. ROS production is co-located in the mitochondria, and …