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Articles 811 - 840 of 8516
Full-Text Articles in Entire DC Network
Neutral-Current Neutral Pion Production Measurement In Microboone Using Wirecell, Giacomo Scanavini
Neutral-Current Neutral Pion Production Measurement In Microboone Using Wirecell, Giacomo Scanavini
Yale Graduate School of Arts and Sciences Dissertations
This dissertation presents the first-ever measurements of the inclusive flux-averaged differential cross sections for neutral-current neutral pion production in $\pi^0$ momentum and cos$\theta$ on argon, as well as exclusive cross section measurements based on proton multiplicity. The NC$\pi^0$ channel is a significant source of photon background in long-baseline neutrino oscillation appearance searches and in NC$\Delta$ single-gamma production rate in MicroBooNE. The lack of previous measurements in the sub-GeV to few GeV neutrino energy region, specifically on argon, makes this investigation a priority.The measurements were conducted using the MicroBooNE detector, which is a Liquid Argon Time Projection Chamber exposed to the …
First Measurement Of Inclusive Muon Neutrino Charged Current Triple-Differential Cross Section On Argon, London Cooper-Troendle
First Measurement Of Inclusive Muon Neutrino Charged Current Triple-Differential Cross Section On Argon, London Cooper-Troendle
Yale Graduate School of Arts and Sciences Dissertations
The field of accelerator neutrino experiments is entering an era of precision oscillation measurements in which many of the remaining unknown neutrino measurements will be determined. The upcoming DUNE and Hyper-K experiments aim to determine the neutrino mass hierarchy and degree of Charge-Parity (CP) violation in the neutrino sector, providing potential insight on the matter-antimatter imbalance observed in the universe. However, these experiments require highly accurate measurements, and neutrino cross section modeling uncertainties may limit their capabilities. Cross section measurements at current-generation experiments can aid the development of neutrino interaction models to reduce these uncertainties. This is especially true for …
Essays On Civil Procedure: Remedies, Federal Courts, And Marginalized Groups, Portia Pedro
Essays On Civil Procedure: Remedies, Federal Courts, And Marginalized Groups, Portia Pedro
Yale Graduate School of Arts and Sciences Dissertations
This dissertation is a series of essays on the processes that judges use to make procedural decisions and the ways in which judges use procedure to navigate the tensions between law and equity, standards and rules, finality and fairness, and states and marginalized groups. It explores the procedure of procedure—how procedure develops and what hinders or furthers procedural decisionmaking. Some of these essays describe the ways in which racial subordination and the subordination of other marginalized groups manifest in civil procedure, remedies, and federal courts. The dissertation challenges the dominant understanding of these three areas of law as neutral and …
Essays In Public Economics, Jintaek Song
Essays In Public Economics, Jintaek Song
Yale Graduate School of Arts and Sciences Dissertations
This dissertation includes two chapters on public economics and health economics, centered around designing public policies when agents make behavioral mistakes. In the first chapter, I study the nono-fungibility of SNAP and its normative implications. The second chapter studeis the optimal design of the health insurance when when the insurers can use bureaucratic cost as a policy instrument.The first chapter studies the non-fungibility of SNAP and its normative implications using novel consumer panel data of shopping history across multiple grocery retailers and restaurants. Exploiting a recent state-level policy change in the amount of SNAP benefits, I estimate that the propensity …
Approximate Message Passing Algorithms For General Random Matrices, Xinyi Zhong
Approximate Message Passing Algorithms For General Random Matrices, Xinyi Zhong
Yale Graduate School of Arts and Sciences Dissertations
Approximate Message Passing algorithms are a versatile family of iterative algorithms that have found applications in various statistical problems. This thesis highlights some of the recent advancements that generalize the applicability of AMP. First, we analyze the universality of AMP algorithms, showing that their state evolutions hold over a broader range of random matrices, including those with heavy-tailed entries and heterogeneous entry-wise variances. Second, we explore extensions of AMP algorithms of multi-variate iterates with spectral initialization for rotationally invariant matrices, to handle data matrices with correlated noise entries. Lastly, we investigate practical AMP procedures for inference under the Bayesian framework …
Applications Of Multiple Lasers In Mass Spectrometry: Structural Characterization And Kinetic Measurements Of The Size- And Temperature-Dependent Water-Mediated Proton-Transfer Reaction In Microhydrated 4-Aminobenzoic Acid, Thien Tung Khuu
Yale Graduate School of Arts and Sciences Dissertations
The goal of this thesis is to explore the critical role played by water molecules in the proton migration between two spectroscopically distinct protonation sites adopted by 4-amninobenzoic acid (4ABA). This ultimate goal is achieved through several elementary steps. First, structural characterizations of the two protomers (with and without water molecules), one with the protonation site occurs at the acid group (the O-protomer) and one with the protonation site occurring at the amine functionality (the N-protomer), are explored in detail. Then, to capture the slow water-mediated, proton-transfer process at cold temperature, modifications were made to the current hybrid …
Computational Studies Of The Mechanical Properties Of Metallic Glasses, Aya Nawano
Computational Studies Of The Mechanical Properties Of Metallic Glasses, Aya Nawano
Yale Graduate School of Arts and Sciences Dissertations
Metallic glasses are alloys with amorphous atomic structures. They possess promising mechanical properties such as larger values for the strength and elastic limit compared to those for conventional crystalline alloys; however, they are typically brittle under tensile loading at room temperature. To use metallic glasses as structural materials, it is important to develop methods to predict their mechanical response as a function of the microstructure prior to loading. We developed a novel coarse-grained spring network model, which describes the mechanical response of metallic glasses using an equivalent series network of springs that can break and re-form to mimic atomic rearrangements …
Discovery And Synthesis Of N-Heterocyclic Drug-Like Compounds By Leveraging Novel Rh(I)-Catalyzed C-H Activation Methods, Oh Sang Kweon
Discovery And Synthesis Of N-Heterocyclic Drug-Like Compounds By Leveraging Novel Rh(I)-Catalyzed C-H Activation Methods, Oh Sang Kweon
Yale Graduate School of Arts and Sciences Dissertations
Nitrogen heterocycles are present in almost two-thirds of U.S. FDA approved pharmaceuticals, as well as biologically active natural products. The first two chapters discuss the application of C-H activation methodology to explore novel, nitrogen heterocycle containing molecules as potent and selective ligands towards different protein targets. The third chapter depicts the design of new N-heterocyclic covalent molecular probes that uniquely labels a serine hydrolase protein in a chemoproteomics screen. Chapter 1 details an investigation using structure-based docking with a virtual library of tetrahydropyridines (THPs) to identify unique agonists for the serotonin 5-HT2A receptor (5-HT2AR). Based around combinations of three inputs, …
Specificity And Regulation Of Sodium Channel Trafficking: Exploring A Novel Therapeutic Strategy For Pain, Grant Philip Higerd-Rusli
Specificity And Regulation Of Sodium Channel Trafficking: Exploring A Novel Therapeutic Strategy For Pain, Grant Philip Higerd-Rusli
Yale Graduate School of Arts and Sciences Dissertations
The burden of pain is significant and current pain treatments are often ineffective. Opiate use has led to an epidemic, requiring alternative pain medications that are more effective and non-addictive. Voltage-gated sodium channel NaV1.7 is preferentially expressed in pain-sensing neurons. Mutations in NaV1.7 can cause disorders ranging from intense pain to complete painlessness in humans, suggesting that its inhibition could provide analgesia without CNS side-effects or addictive potential. Indeed, existing non-selective NaV channels blockers prevent pain, but their utility is limited due to serious side-effects caused by inhibition of NaV isoforms expressed in the heart and brain. Selective inhibition of …
Perspective Differentiation With Diffusion Geometry, Benjamin Ekeroth
Perspective Differentiation With Diffusion Geometry, Benjamin Ekeroth
Yale Graduate School of Arts and Sciences Dissertations
Extracting the common information amongst a collection of datasets has become a majortopic of research called Sensor Fusion. Instead, we explore a collection of methods for extracting the information which differentiates between collections of datasets. We focus on methods for differentating the perspectives of datasets using diffusion operators. We formulate a minimax problem for optimizing the relative smoothness of functions between collections of graphs, and prove a minimax theorem for generalized eigenvalues to compute the solution. We further investigate methods for extracting control variables from multidimensional time-series, motivated by a differentiation problem in stroke detection.
The Federal Regulators' Response To Recent Bank Failures: Hearing Before The Committee On Financial Services: U.S. House Of Representatives: One Hundred Eighteenth Congress First Session, United States Government
The Federal Regulators' Response To Recent Bank Failures: Hearing Before The Committee On Financial Services: U.S. House Of Representatives: One Hundred Eighteenth Congress First Session, United States Government
Documents
No abstract provided.
Recent Bank Failures And The Federal Regulatory Response: Hearing Before The Committee On Banking, Housing, And Urban Affairs: United States Senate: One Hundred Eighteenth Congress First Session On Examining The Recent U.S. Bank Failures And The Federal Regulators' Response, United States Government
Documents
No abstract provided.
Dichloroacetate As A Metabolic Treatment For Glioblastoma, Megan Macia
Dichloroacetate As A Metabolic Treatment For Glioblastoma, Megan Macia
Yale School of Medicine Physician Associate Program Theses
Glioblastoma is the most common aggressive primary brain tumor in adults, and there is no current standard of care for progression. The Warburg effect is a known part of cancer’s metabolic reprogramming and has been studied as a possible target for limiting tumor growth. Dichloroacetate, a pyruvate dehydrogenase kinase inhibitor, has been proposed as a treatment for glioblastoma, and the drug has had success in phase 1 trials. The proposed study is an open-label, randomized phase 2 clinical trial. Participants will be randomized to oral dichloroacetate, with dosing based on genetic testing, or to a control group treated with lomustine. …
A Cross Sectional Review: Effects Of Dehydration On Subdural Hematoma Risk In Athletes, Lina Nguyen
A Cross Sectional Review: Effects Of Dehydration On Subdural Hematoma Risk In Athletes, Lina Nguyen
Yale School of Medicine Physician Associate Program Theses
Subdural hematomas are precedent to nearly all catastrophic head injuries in athletics, and are a leading cause of death and morbidity in sports. While known risk factors exist, cases still occur in young, healthy athletes without clear predisposition– occasionally without a precipitating traumatic event. Athletes are at increased susceptibility for dehydration, and the effects of inadequate fluid status on subdural risk is unknown. This study aims to elucidate the relationship between dehydration during athletic activity and subdural hematoma formation. We propose a cross-sectional study utilizing Yale New Haven Hospital electronic medical records, where we compare hydration status at emergency room …
Single Supervisory Mechanism, European Central Bank (Ecb)
Single Supervisory Mechanism, European Central Bank (Ecb)
Documents
No abstract provided.
About Rigsrevisionen, Denmark: Rigsrevisionen
Svb Financial Group Announces Proposed Offerings Of Common Stock And Mandatory Convertible Preferred Stock, Svb Financial Group
Svb Financial Group Announces Proposed Offerings Of Common Stock And Mandatory Convertible Preferred Stock, Svb Financial Group
Documents
No abstract provided.
Ypfs Lessons Learned Oral History Project: An Interview With Luis Jácome, Luis Jácome, Mercedes Cardona
Ypfs Lessons Learned Oral History Project: An Interview With Luis Jácome, Luis Jácome, Mercedes Cardona
Documents
No abstract provided.
Consolidated Reports Of Condition And Income For A Bank With Domestic And Foreign Offices - Ffiec 031 (First Republic 2023), United States: Federal Financial Institutions Examination Council
Consolidated Reports Of Condition And Income For A Bank With Domestic And Foreign Offices - Ffiec 031 (First Republic 2023), United States: Federal Financial Institutions Examination Council
Documents
No abstract provided.
Policies, Projections, And The Social Cost Of Carbon: Results From The Dice-2023 Model, Lint Barrage, William D. Nordhaus
Policies, Projections, And The Social Cost Of Carbon: Results From The Dice-2023 Model, Lint Barrage, William D. Nordhaus
Cowles Foundation Discussion Papers
The present study examines the assumptions, modeling structure, and preliminary results of DICE-2023, the revised Dynamic Integrated Model of Climate and the Economy (DICE), updated to 2023. The revision contains major changes in the carbon and climate modules, the treatment of non-industrial greenhouse gases, discount rates, as well as updates on all the major components. The major changes are a significant reduction in the target for the optimal (cost-beneficial) temperature path, a lower cost of reaching the 2 °C target, an analysis of the impact of the Paris Accord, and a major increase in the estimated social cost of carbon.
The Effect Of Education Policy On Crime: An Intergenerational Perspective, Costas Meghir, Marten Palme, Marieke Schnabel
The Effect Of Education Policy On Crime: An Intergenerational Perspective, Costas Meghir, Marten Palme, Marieke Schnabel
Cowles Foundation Discussion Papers
We study the intergenerational effect of education policy on crime. We use Swedish administrative data that links outcomes across generations with crime records and we show that the comprehensive school reform, gradually implemented between 1949 and 1962, reduced conviction rates both for the generation directly affected by the reform and for their sons. The reduction in conviction rates occurred across many types of crime. Key mediators for this reduction in the child generation are an increase in education and a decline in crime amongst their fathers.
Corrected-Portugal Closes Novo Banco's Access To State Funding After Restructuring - Ministry, Sergio Goncalves
Corrected-Portugal Closes Novo Banco's Access To State Funding After Restructuring - Ministry, Sergio Goncalves
Documents
No abstract provided.
Consolidated Reports Of Condition And Income For A Bank With Domestic And Foreign Offices - Ffiec 031, Silicon Valley Bank Financial Group
Consolidated Reports Of Condition And Income For A Bank With Domestic And Foreign Offices - Ffiec 031, Silicon Valley Bank Financial Group
Documents
No abstract provided.
Form 10-K (2022), First Republic Bank
Ypfs Lessons Learned Oral History Project: An Interview With Jeremy Rudin, Jeremy Rudin, Rosalind Wiggins, Mary Anne Chute Lynch
Ypfs Lessons Learned Oral History Project: An Interview With Jeremy Rudin, Jeremy Rudin, Rosalind Wiggins, Mary Anne Chute Lynch
Documents
No abstract provided.
Money Market Mutual Funds: Pandemic Revealed Unresolved Vulnerabilities, United States Government Accountability Office
Money Market Mutual Funds: Pandemic Revealed Unresolved Vulnerabilities, United States Government Accountability Office
Documents
No abstract provided.
The Limits To A Moratorium: Interplay Between The Indian Insolvency And Bankruptcy Code And Defensive Proceedings, Abhijnan Jha, Chetan Chawla
The Limits To A Moratorium: Interplay Between The Indian Insolvency And Bankruptcy Code And Defensive Proceedings, Abhijnan Jha, Chetan Chawla
Documents
No abstract provided.
Svb Q4 2022 Financial Highlights, Silicon Valley Bank
Extreme Points Of First-Order Stochastic Dominance Intervals: Theory And Applications, Kai Hao Yang, Alexander K. Zentefis
Extreme Points Of First-Order Stochastic Dominance Intervals: Theory And Applications, Kai Hao Yang, Alexander K. Zentefis
Cowles Foundation Discussion Papers
We characterize the extreme points of first-order stochastic dominance (FOSD) intervals and show how these intervals are at the heart of many topics in economics. Using knowledge of these extreme points, we characterize the distributions of posterior quantiles under a given prior, leading to an analogue of a classical result regarding the distribution of posterior means. We apply this analogue to various economic subjects, including the psychology of judgement, political economy, and Bayesian persuasion. In addition, FOSD intervals provide a common structure to security design. We use the extreme points to unify and generalize seminal results in that literature when …
Ypfs Lessons Learned Oral History Project: An Interview With Philip Lane, Rosalind Z. Wiggins, Mary Anne Chute Lynch
Ypfs Lessons Learned Oral History Project: An Interview With Philip Lane, Rosalind Z. Wiggins, Mary Anne Chute Lynch
Documents
No abstract provided.