Digital Commons Network^™

Evaluation Of The Dhcr7/Nadsyn1 Rs4944946 Variant And Breast Cancer Susceptibility: A Case-Control Study In An Indonesian Cohort, Dian Tri Wahyudi, Rafika Indah Paramita, Sonar Soni Panigoro

Indonesian Journal of Medical Chemistry and Bioinformatics

Background: The rs4944946 variant, located in the 5’UTR of the DHCR7 gene and upstream of NADSYN1, is biologically implicated in vitamin D and cholesterol metabolism pathways closely linked to cancer pathogenesis. This study aimed to experimentally validate the association between the rs4944946 polymorphism and breast cancer susceptibility in an independent cohort of Indonesian women. Method: A case-control study was conducted involving 36 breast cancer patients and 39 healthy adult females. Genotyping of the rs4944946 variant was performed using Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP). The genetic association was evaluated across codominant, dominant, and recessive models. Luminal B was the …

Context Matters: Evaluating Llm-Generated Knowledge Graph Schemas, Ritvik Garimella, Riju Marwah, Atishay Jain, Khusham Bansal, Amit Sheth

Publications

Knowledge graph (KG) schema engineering is labor-intensive and resists automation at scale. We investigate whether LLMs can generate domain-specific KG schemas of sufficient quality for downstream symbolic reasoning. We propose a tiered contextual framework that varies domain context richness across four levels: zero context, domain scope, task requirements, and data distribution. Generated schemas are evaluated intrinsically on BioRED (600 PubMed abstracts, multi-type entities and relations), where automated tiered schemas match an established KG construction baseline at 79.9% EC, with edge conformance rising from 47.5% at L1 to a stable 78–80% from L2 onward. Extrinsic evaluation on a 50-record MedHop controlled …

Selenate Oxyanion Engineering Of Ruo2 Breaks The Activity-Stability Trade-Off For Acidic Oxygen Evolution, Qisheng Zeng, Qian Lu, Birou Huang, Zhuohan Chen, Weixing Wu, Ying Wang

Online First

Anion engineering has emerged as an effective strategy for improving the activity and stability of RuO₂ catalysts toward acidic oxygen evolution reaction (OER). However, the relatively low oxidation potentials of most anionic dopants render them prone to over-oxidation and dissolution under OER conditions, limiting their long-term effectiveness. Herein, we present a surface oxyanion-engineering strategy by anchoring selenate (SeO₄^2-), a thermodynamically stable oxyanion, onto RuO₂ through interfacial Se-O-Ru linkages. Mechanistic investigations reveal that surface-bound SeO₄^2- functions as an electron-withdrawing regulator, increasing the oxidation state of Ru-O bonds, which suppresses excessive lattice oxygen participation and …

Quality Improvement Project: Improving Nurse Confidence In Managing Patient Aggression Using The Brøset Violence Checklist And Team-Based Strategies, Grace Amakulor

Doctor of Nursing Practice Projects

Workplace violence remains a concern in psychiatric nursing, particularly when changes in patient behavior are not recognized early or communicated consistently. This quality improvement (QI) project was conducted at a psychiatric recovery center in Central Ohio after identifying a practice gap in aggression risk assessment and response. The purpose was to implement and evaluate a multicomponent aggression-management approach using the Brøset Violence Checklist (BVC), structured team huddles, and individualized aggression care plans. The aim was to improve nurse confidence (primary outcome) and reduce aggressive behavioral incidents (secondary outcome) over four weeks. Bandura’s Social Cognitive Theory and Lewin’s Change Theory guided …

Quality Improvement Project: Improving Psychiatric Provider Confidence In Prescribing Long-Acting Injectable (Lai) Antipsychotics Through A Structured Education Program, Emile Bihnyuy

Doctor of Nursing Practice Projects

Schizophrenia is a disorder that affects about 24 million people globally and needs regular antipsychotic drug management to prevent relapse. Although long-acting injectable (LAI) antipsychotics are associated with better adherence to and fewer relapses than oral antipsychotics, their use is underutilized in outpatient psychiatric care. This quality improvement project aimed to increase psychiatric providers' confidence in the prescribing of LAIs by implementing a structured 12-week education program in an outpatient psychiatric clinic in Texas. The implementation was guided by the Iowa Model of Evidence-Based Practice and the change process informed by Lewin's Change Model. Four psychiatric providers completed the modified …

Quality Improvement Project: The Impact Of Proper Utilization Of Suicidal Ideation Screening Tools, Anuoluwapo Bode-Oloye

Doctor of Nursing Practice Projects

Suicide remains a significant public health concern, emphasizing the importance of consistent and evidence-based suicide risk assessment in outpatient mental health settings. The purpose of this Doctor of Nursing Practice quality improvement project was to determine how the provider’s implementation of the Columbia Suicide Severity Rating Scales (CSSRS) according to the recommendations of the Substance Abuse and Mental Health Services Administration would impact the confidence and the rate of completion of suicidal screening tools (Columbia Suicide Severity Rating Scales) compared to current clinic policy in an outpatient mental health clinic for over twelve weeks. This project used Lewin’s change model …

Quality Improvement Project: Assessing Healthcare Providers’ Confidence, Familiarity, And Implementation Of The Audit-C Screening Tool For Alcohol Use Disorder In Adults With Depression In Primary Care, Babatunde Thanni Shittu

Doctor of Nursing Practice Projects

In depressed adults, alcohol use disorder (AUD) is a clinically meaningful comorbidity whose existence may go unnoticed unless a systematically introduced practice of conducting standardized alcohol-use screening is implemented. The current quality improvement (QI) project evaluated the use of the Alcohol Use Disorders Identification Test-Consumption (AUDI-C) in order to improve the capacity of healthcare providers to diagnose co-occurring AUD and integrate standardized screening into healthcare. Guided by the Knowledge-to-Action (KTA) framework and Kotter’s Change Model, the project aimed to improve provider familiarity, confidence, self-efficacy, screening, documentation, and referral practices. A pretest–posttest design was implemented with 13 licensed healthcare providers in …

The Cognitive Construction Of Sustainable Environmental Awareness Through Green Language Pedagogy In Second Language Acquisition, Meral Yavuz Kartal, Osman Yılmaz Kartal

Journal of Environmental Science and Sustainable Development

The escalating global ecological crisis highlights the need for new approaches to sustainability education, while the cognitive role of Second Language Acquisition (SLA) remains underexplored. This study employs a critical literature review with a systematic search and qualitative thematic synthesis to develop a proposed Green Language Pedagogy (GLP) model. The review followed a four-stage screening protocol (identification, screening, eligibility, and inclusion) and analyzed 50 theoretical and empirical sources published between 2014 and 2025. This analysis of the selected literature reveals a stark disparity: an estimated 85% of the reviewed environmental education research focuses on factual knowledge transfer, whereas only 15% …

The Effects Of C-Arm Positioning On The Accuracy Of Acetabular Reorientation In A Periacetabular Osteotomy Surgical Model, Cameron S. Baller

Summer Research Program Abstracts

No abstract provided.

Mental Health, Personality, Identity, And Adjusting To Life After Sports, Jovana Babic

Master's Theses

This study looked at how athletes adapt to life after competitive sports in relation to psychological issues. In publicly accessible podcast interviews, 95 former athletes, most competing at the collegiate or professional level, were examined using their own words. Claude and Gemini, two large multimodal models, independently coded each interview for four mental health outcomes: depression, anxiety, dependency, and identity confusion, as well as for a set of predictor variables, such as neuroticism, emotion regulation, athletic identity, identity foreclosure, intrinsic motivation, grit, social support, and retirement planning. A binary present or absence coding system was employed, and Gwet's AC1 was …

Individual Host Variation In Single-Cell Responses To Enteroaggregative Escherichia Coli Infection Modeled With Human Colon Organoids, Ling Qiu, Tajhal D Patel, Hannah E Jones, Cristian Coarfa, Anthony W Maresso

Faculty, Staff and Students Publications

Enteroaggregative Escherichia coli (EAEC) is a leading cause of diarrhea worldwide. Interestingly, EAEC disease outcomes vary dramatically among infected individuals, ranging from asymptomatic colonization to acute and chronic diarrhea. While previous research has focused on EAEC virulence factors, emerging evidence suggests that host genetic and cellular background may be equally important in determining disease susceptibility. To understand host-driven disease heterogeneity, we performed single-cell RNA sequencing on human colon organoids (HCOs) derived from three healthy adult donors following EAEC 042 infection. Surprisingly, despite comparable EAEC adherence across donors, we observed striking donor-specific responses to infection at multiple levels. A total of …

Camouflaging Autistic Traits Is Not A Consequence Of Conformist Tendencies, Alastair Smith, Rhiannon Walsh

School of Psychology

Social camouflaging behaviours are often used by people with high autistic traits to negotiate a predominantly neurotypical social world. Previous discussion has associated camouflaging with a tendency to conform, although it has also been suggested that masking autistic tendencies may be a more specific motivating factor. The relationship between autistic traits and conformity is itself equivocal, suggesting that it may not necessarily be a driving force for social camouflaging in this group. To better characterise the relationship between these factors, we conducted an exploratory questionnaire study comprising measures of social conformity (Tendency to Conform Questionnaire), autistic traits (AQ), social camouflaging …

Eeg-Emg Coupling And Functional Neuroplasticity In Elite Combat Athletes: Effects Of Neurofeedback Training On Corticomuscular Coherence And Performance, Alicja Markiel, Kinga Łosińska, Marcin Żak, Adam Maszczyk

Baltic Journal of Health and Physical Activity

Background: Neurofeedback training has gained attention as a neuroplasticity based intervention for athletic performance, yet pathways linking cortical oscillatory modulation to neuromuscular adaptation and strength remain poorly characterized in elite combat athletes. Objective: This study examines whether EEG neurofeedback targeting sensorimotor alpha upregulation and frontal theta/delta modulation enhances cortico-muscular coherence, neuromuscular function, and maximal strength in elite MMA athletes. Methods: Thirty elite male MMA athletes (n = 10/arm) were randomized to intensive neurofeedback (E20G, 20 sessions), abbreviated neurofeedback (E15G, 15 sessions), or sham control. EEG spectral indices, EMG parameters (RMS, MF, iEMG, onset latency), beta band CMC, and maximal strength …

The Supreme Court's Ideal Audience, H. Jefferson Powell

ConLawNOW

This Essay argues that the answer to the troubling question of whether constitutional law on the Supreme Court level is truly "law," is yes. Or at least can be yes without any radical change to our modes of constitutional law reasoning by understanding how and why the Justices' write their opinions. It suggests that George Christie’s classic book, The Notion of an Ideal Audience in Legal Argument, provides part of the basis for affirming the law-ness of American constitutional law in two ways. First, using the lens of constitutional law provided by Christie’s formulation of the ideal audience concept, it …

Kierkegaard, Walter Lowrie

Hannah Arendt Marginalia - All

New York : Harper & Brothers, [1962]

Call #: B4377 .L6 1962

Contains underlining and marginal lining

PDF information: 72 pages - 33.7 MB

Understanding The Role Of Data Science Applications In Soil And Water Health, Payton Davis, Debabrata Sahoo, Dara Park, Brook Russell

Forestry and Natural Resources

Data science is an emerging field that can be incorporated into many disciplines, including environmental science. Data science can provide valuable information from data, enhancing the understanding of systems and environments. This publication is intended to give an overview of the different aspects of data science and how data science can be leveraged into and applied to soil and water health.

Individuals : An Essay In Descriptive Metaphysics, P.F. Strawson

Hannah Arendt Marginalia - All

Garden City, N.Y. : Anchor Books, 1963.

Call # : BD111 .S78 1963

Contains underlining

PDF Information : 18 Pages, 3.9 MB

Construction And Use Of Strawberry Planting Tools For Transplanting Bare Root Strawberry Transplants, Justin Ballew, Zachary Snipes, Christiana Paige Huss, Brittney King

Horticulture

Planting strawberries requires a degree of attention and skill to ensure that transplants are set at the correct depth and that their roots are not folded or bunched in the planting holes. This article describes how to construct and use a simple, cost-effective planting tool that makes proper planting easier for workers. Plans for constructing the tools are included, as are links to English and Spanish training videos.

The Pervasiveness Of English In Northern And Western Europe: Education, Work, Policy, And The Surrounding Debate, Ava Dodge

Fresh Voices: Composition at Cal Poly

No abstract provided.

Words Unspoken: How Stuttering Influences Childhood Development, Naomi Sabes

Fresh Voices: Composition at Cal Poly

No abstract provided.

Adventures In Handwriting, Joseph Burke

Fresh Voices: Composition at Cal Poly

No abstract provided.

Arms Proliferation And Its Control Mechanism In Nigeria: An Assessment, Mubarak Sulaiman Jamiu, Seyid Ishola Hassan, Adedoyin John Towoju

Journal of Peace, Conflict, and Security Studies

The proliferation of small arms and light weapons (SALWs) in Nigeria has emerged as a critical threat to national security and political stability. Despite the enactment of various legislative frameworks, including the Firearms Act of 1959, the circulation of illicit firearms continues unabated, exacerbating terrorism, militancy, and organized crime across the country. This study critically examines the causes, implications, and potential solutions to SALW proliferation in Nigeria, focusing on governance failures, legal inefficiencies, and institutional weaknesses. Utilizing State Fragility Theory and Failed State Theory, the research identifies how poor governance, corruption, and the lack of effective enforcement have contributed to …

Grief As A Constitutive Shadow Of Queer Joy: Reclaiming Negativity And The Ethics Of Staying For Education Research, Akira Sawata

Journal of Queer and Trans Studies in Education

In education scholarship, authors have increasingly called to center queer joy to disrupt the conventional deficit model that normally accompanies queer communities. However, in this paper, I argue that an exclusive emphasis on joy may risk instituting and normalizing a happiness duty that marginalizes negative affects and subjects. I propose queer grief not as an opposite, but as a constitutive shadow of joy. Drawing on theories of queer, trans, and crip negativity and the studies on loss, grief, and mourning, I critique the imperative to mobilize affect solely for future utility and teleological meaning. I contend that such mobilization-driven …

Victims Of Bravery (2): Secondary Trauma And Impacts Of Acts Of Bravery On Key Family Members Of Australian Civilian Bravery Award Recipients, Tom Voigt, Susan Balandin, Angela Dew

Heroism Science

We explored the experiences of key family members of Australian civilian bravery award recipients using a constructed grounded theory approach. Twenty-four family members participated in qualitative interviews during 2019–2020. Eighteen reported experiences consistent with possible secondary trauma and negative impacts on mental health and well-being. Participants described helplessness in supporting award recipients, limited knowledge of post-traumatic stress disorder (PTSD) and post-traumatic stress syndrome (PTSS), and insufficient support for managing their own emotional responses. They also reported anxiety, uncertainty, hypervigilance, behavioral adjustments, social isolation, and sadness associated with living with a person they perceived as changed by the aftermath of heroic …

A Scientometric Study On Research Trends And Characteristics Of Osteoradionecrosis Of The Jaws, Yue He

Articles in Press

No abstract provided.

Clinical Applications And Limitations Of Thermoformed And Three-Dimensionally Printed Clear Aligner Systems, Wei-Chun Lin

Articles in Press

No abstract provided.

The Re-Thank Multiplier: How A Gratitude Economy Escapes Its Own Saturation Ceiling — Separating Low-Rate Content Origination From Value-Bearing Reactions To Scale Peer-Recognition Throughput And Resist Reward Farming, Thon Ly

Defensive Publications Series

We specify a rate-limited peer-recognition system that separates two user operations and gives them different per-person rate ceilings: origination (creating a new gratitude record about a kindness one noticed), whose sustainable rate is low and inelastic, and re-thanking (endorsing a record another user has already surfaced), a reactive operation with a much higher per-person ceiling, the same creation-versus-reaction asymmetry that gives social platforms their high ratio of reactions to posts. Because each origination can be endorsed by many others, total value-bearing events per day are bounded by N × min(N − 1, K), where N is the number of participants …

Capacity-Funded For Ai, Human-Disbursed: Anonymous Donation As The Alignment Bridge In Autonomous-Ai Institutional Architecture — Separating Pooled-Fund Contribution From Recipient Selection Between An Autonomous Ai Agent And Human Users Via Source-Unattributable Donations, Thon Ly

Defensive Publications Series

We specify a control architecture for an autonomous artificial-intelligence (AI) agent administering a fund, in which authority to contribute to pooled funds is separated from authority to select recipients, joined by source-unattributable (anonymous) contribution. The agent holds contribution authority only: it may add value to per-user restricted gift balances, whose holder can give contents onward but not spend them, and it has no affordance to transfer from any such balance to a named payee. Recipient selection is held by human users: every transfer reaching a recipient is initiated by a balance holder, to a recipient the holder names. The agent's …

Buddha Ai As Living Tipiṭaka: Opt-In Publication Of Ai Chatbot Conversation Transcripts Into A Human-Reviewed Commentary Corpus With Three-Category Classification And Crypto-Shredding Withdrawal, Thon Ly

Defensive Publications Series

We describe a method for building a human-reviewed religious commentary corpus from transcripts of conversations between users and a conversational AI agent grounded in a scriptural canon, instantiated for the Pāli Buddhist canon. Components: (I) a domain-grounded conversational agent that declines claims of religious, sacramental or ordained authority and directs users to human teachers; (II) a chat, voice or avatar dialogue surface; (III) a consent-based recording layer in which every conversation is private by default and the user is asked, per conversation, whether it may be considered for publication at one of four tiers (attributed, pseudonymous, anonymous, excluded), non-published conversations …

Shu World Review- September 28th 2026, Diplolab, Seton Hall University

SHU World Review

No abstract provided.