Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Wright State University

Discipline
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 1681 - 1710 of 7018

Full-Text Articles in Entire DC Network

The Effect Of Laser Power And Scan Speed On Melt Pool Characteristics Of Pure Titanium And Ti-6al-4v Alloy For Selective Laser Melting, Chandrakanth Kusuma Jan 2016

The Effect Of Laser Power And Scan Speed On Melt Pool Characteristics Of Pure Titanium And Ti-6al-4v Alloy For Selective Laser Melting, Chandrakanth Kusuma

Browse all Theses and Dissertations

Selective Laser Melting (SLM) is an additive manufacturing (AM) technique that creates complex parts by selectively melting metal powder layer-by-layer. In SLM, the process parameters decide the quality of the fabricated component. In this study, single beads of commercially pure titanium (CP-Ti) and Ti-6Al-4V alloy are melted on a substrate of the same material as powder using an in-house built SLM machine. Multiple combinations of laser power and scan speed are used for single bead fabrication while the laser beam diameter and powder layer thickness are kept constant. This experimental study investigates the influence of laser power, scan speed and …

Go to article

Terahertz Spectroscopic Breath Analysis As A Viable Analytical Chemical Sensing Technique, Robert M. Schueler Jan 2016

Terahertz Spectroscopic Breath Analysis As A Viable Analytical Chemical Sensing Technique, Robert M. Schueler

Browse all Theses and Dissertations

The ability to quantify trace chemicals in human breath enables the possibility of identifying breath biomarkers to aid in diagnosis. The vast majority of the studies in the analytical breath analysis rely on GC-MS techniques for quantification of the human breath composition1,2,3,4. THz spectroscopy of breath is rapid, sensitive, and highly specific molecular identification in complex mixtures containing 10-100 analytes with near `absolute' specificity. THz spectroscopic breath analyzers require chemical preconcentration. A newly developed custom preconcentrator was constructed and compared in its performance to a commercial system. Unlike the commercial counterpart, the new system does not require cryogenic liquids, is …

Go to article

Comparing Antibody-Coated Immune Beads With Flow Cytometry To Measure Ss-2-Microglubulin+ Murine Spleen Cells, Amal Fahad Alajman Jan 2016

Comparing Antibody-Coated Immune Beads With Flow Cytometry To Measure Ss-2-Microglubulin+ Murine Spleen Cells, Amal Fahad Alajman

Browse all Theses and Dissertations

In diseases like AIDS, Multiple Myeloma, Multiple Sclerosis (MS), Type 1 Diabetes, and Systemic Lupus Erythromatosus the detection of major histocompatibility complex type 1 molecules (MHC 1) can be a helpful component of disease diagnosis and prognosis. Most somatic mammalian cells display to varying degrees major histocompatibility complex (MHC) class 1 antigen on the cell surface. MHC1 molecules consist of a polymorphic alpha a chain and a monomorphic beta chain, beta 2 microglubulin (ß2m). The ß2M composition is fairly constant within a species whereas the alpha chain is not. The polymorphic alpha chain is encoded by an MHC complex gene …

Go to article

The Impact Of Hsv-1 Infection, Socs1 Peptide, And Socs3 Peptide Mimetic On Cell Viability, Morphology, And Cytoskeleton Proteins Of Unpolarized And Cytokine-Polarized M1 Raw 264.7 Murine Macrophages, Mubarak Almutairi Jan 2016

The Impact Of Hsv-1 Infection, Socs1 Peptide, And Socs3 Peptide Mimetic On Cell Viability, Morphology, And Cytoskeleton Proteins Of Unpolarized And Cytokine-Polarized M1 Raw 264.7 Murine Macrophages, Mubarak Almutairi

Browse all Theses and Dissertations

Mubarak Huraysan Almutairi. M.S. Department of Microbiology and Immunology, Wright State University, 2016. The Impact of HSV-1 Infection, SOCS1 peptide, and SOCS3 peptide mimetic on Cell Viability, Morphology, and Cytoskeleton Proteins of Unpolarized and Cytokine-Polarized M1 RAW 264.7 Murine Macrophages. The immune response against HSV-1 involves macrophages in both innate and adaptive immunity by limiting HSV-1 replication. In this study, the effects of HSV-1 challenge on cell viability, morphology, and cytoskeletal filament in unpolarized and cytokine-polarized murine RAW 264.7 macrophages at 24 and 48 hours were monitored. Because the distribution of cytoskeleton throughout the cell is critical in cell viability …

Go to article

Knowledge-Empowered Probabilistic Graphical Models For Physical-Cyber-Social Systems, Pramod Anantharam Jan 2016

Knowledge-Empowered Probabilistic Graphical Models For Physical-Cyber-Social Systems, Pramod Anantharam

Browse all Theses and Dissertations

There is a rapid intertwining of sensors and mobile devices into the fabric of our lives. This has resulted in unprecedented growth in the number of observations from the physical and social worlds reported in the cyber world. Sensing and computational components embedded in the physical world constitute a Cyber-Physical System (CPS). Current science of CPS is yet to effectively integrate citizen observations in CPS analysis. We demonstrate the role of citizen observations in CPS and propose a novel approach to perform a holistic analysis of machine and citizen sensor observations. Specifically, we demonstrate the complementary, corroborative, and timely aspects …

Go to article

Routes To 1,3,4 - Oxadiazol-2(3h)-Ones, Karunakar Reddy Madaram Jan 2016

Routes To 1,3,4 - Oxadiazol-2(3h)-Ones, Karunakar Reddy Madaram

Browse all Theses and Dissertations

Various 1,3,4-oxadiazol-2(3H)-ones were synthesized by reaction of the bromocarbonylhydrazine salt(35) obtained from treatment of 4-bromo-3-phenylsydnone(34) with HCl with the corresponding acid chlorides in DME. The structures were confirmed by their physical, analytical and spectral data (IR, GC/MS, 1H and 13C NMR and CHN analysis). In general these compounds were synthesized in good to excellent yields and it is planned to continue exploration of their chemical behavior as a guide to their potential antimicrobial activity. As an initial approach to the synthesis of the desired 1,3,4-oxadiazol-2(3H)-ones, the starting material, 3-phenylsydnone, was prepared in 2 steps from commercially available N-phenylglycine in good …

Go to article

Fault Diagnosis And Fault-Tolerant Control Of Quadrotor Uavs, Remus C. Avram Jan 2016

Fault Diagnosis And Fault-Tolerant Control Of Quadrotor Uavs, Remus C. Avram

Browse all Theses and Dissertations

Quadrotors represent a special class of Unmanned Aerial Vehicles (UAVs) and have attracted significant attention in recent years due to their potential in various military and civilian applications. However, due to their intrinsic fabrication process and component damage, quadrotors are prone to various type of faults. This dissertation presents the design, analysis, and experimental implementation of fault diagnosis, fault-tolerant control, and controller verification methods to achieve safety assurance and trusted autonomy of quadrotor UAVs. First, the issue of sensor faults is investigated under two different scenarios: (1) the case when all Euler angles are available for measurement; (2) the case …

Go to article

Resqu: A Framework For Automatic Evaluation Of Knowledge-Driven Automatic Summarization, Nishita Jaykumar Jan 2016

Resqu: A Framework For Automatic Evaluation Of Knowledge-Driven Automatic Summarization, Nishita Jaykumar

Browse all Theses and Dissertations

Automatic generation of summaries that capture the salient aspects of a search resultset (i.e., automatic summarization) has become an important task in biomedical research. Automatic summarization offers an avenue for overcoming the information overload problem prevalent in large online digital libraries. However, across many of the knowledge-driven approaches for automatic summarization it is not always clear which features highly impact or influence the quality of a summary. Instead, there has been considerable focus on utilizing schema knowledge to facilitate browsing and exploration of generated summaries a posteriori. Informative features should not be ignored, since they could be utilized to help …

Go to article

Heating Power Of Coated Fecov Magnetic Nanoparticles, Hanaa Ali Alshammari Jan 2016

Heating Power Of Coated Fecov Magnetic Nanoparticles, Hanaa Ali Alshammari

Browse all Theses and Dissertations

The effect of coatings on the heating curves of magnetic nanoparticles was studied in this Thesis. Iron cobalt vanadium (FeCoV) nanoparticles with oxide (CoOFe2O3) and graphite (C) coating to prevent oxidation, were synthesized through thermal plasma processing method. The magnetic nanoparticles had an average diameter of 30 nm. In the case of FeCoV with oxide coating, the initial diameter of the pure FeCoV nanoparticles on average was 30 nm but after oxidation 5 nm thick oxide layer was created. As a result of this oxidation, the magnetic core of FeCoV nanoparticles was shrunk from 30 nm to 20 nm in …

Go to article

Determination Of Atmospheric Particulate Matter Composition In The Dayton Metro Area, Saagar Mahendra Patel Jan 2016

Determination Of Atmospheric Particulate Matter Composition In The Dayton Metro Area, Saagar Mahendra Patel

Browse all Theses and Dissertations

Quartz filters from high-volume air samplers of particulate matter of a size less than 10 micrometers in diameter (PM10) located in Moraine and Yellow Springs, Ohio, were obtained from the Regional Air Pollution Control Agency and analyzed for levoglucosan, metals, and the EPA 16 priority polycyclic aromatic hydrocarbons (PAHs). Average concentration of levoglucosan increased as ambient temperature decreased. Winter concentrations of levoglucosan for Moraine and Yellow Springs were 39.41 ± 31.58 µg/g and 51.52 ± 27.44 µg/g, respectively, which is due to a greater amount of residential wood burning in the colder months. The concentration of biomass burning …

Go to article

Use Of Clearview Gel Dosimeter For Quality Assurance And Testing Of Stereotactic Radiosurgery, Erik Joseph-Leonard Courter Jan 2016

Use Of Clearview Gel Dosimeter For Quality Assurance And Testing Of Stereotactic Radiosurgery, Erik Joseph-Leonard Courter

Browse all Theses and Dissertations

There exists a lack of accurate, reproducible three-dimensional dosimetry techniques for stereotactic radiosurgery (SRS) commissioning and quality assurance. This experiment evaluates the use of ClearView gel dosimeters as an alternative to current methods for small field dosimetry in SRS testing. ClearView differs from other gel dosimeters in that it uses tetrazolium salt in its chemical make-up in place of traditional Fricke-type compounds. Using a Varian TrueBeam radiotherapy system to deliver the radiation, three vials of ClearView gel dosimeter were tested in three different dose delivery scenarios. The first test examined the dosimeter's response to a static beam with the dose …

Go to article

Fpga Realization Of Low Register Systolic All One-Polynomial Multipliers Over Gf (2M) And Their Applications In Trinomial Multipliers, Pingxiuqi Chen Jan 2016

Fpga Realization Of Low Register Systolic All One-Polynomial Multipliers Over Gf (2M) And Their Applications In Trinomial Multipliers, Pingxiuqi Chen

Browse all Theses and Dissertations

All-one-polynomial (AOP)-based systolic multipliers over GF (2m) are usually not con-sidered for practical implementation of cryptosystems such as elliptic curve cryptography (ECC) due to security reasons. Besides that, systolic AOP multipliers usually suer from the problem of high register-complexity, especially in field-programmable gate array (FPGA) platforms where the register resources are not that abundant. In this thesis, however, we have shown that the AOP-based systolic multipliers can easily achieve low register-complexity implementations and the proposed architectures can be employed as computation cores to derive ecient implementations of systolic Montgomery multipli-ers based on trinomials, which are recommended by the National Institute …

Go to article

A Theoretical Framework For Evaluating Mental Workload Resources In Human Systems Design For Manufacturing Operations, Sharon Claxton Bommer Jan 2016

A Theoretical Framework For Evaluating Mental Workload Resources In Human Systems Design For Manufacturing Operations, Sharon Claxton Bommer

Browse all Theses and Dissertations

Manufacturing is a human-driven process that applies energy and manpower to produce consumer goods. In repetitive task processes like manufacturing systems, optimal performance is extremely important for the production employee and the company. In the general fast pace of manufacturing operations, there is the potential for operator errors, which correlates to possible safety issues and loss of revenue. This research explores the influence of cognitive resources on operator performance in manufacturing operations using the Multiple Resource Theory (MRT) and mental workload measures. Computer simulation models and mathematical modeling with Improved Performance Research Integration Tool (IMPRINT) were used to assess mental …

Go to article

Performance Prediction Of Constrained Waveform Design For Adaptive Radar, Aaron M. Jones Jan 2016

Performance Prediction Of Constrained Waveform Design For Adaptive Radar, Aaron M. Jones

Browse all Theses and Dissertations

Today's radars face an ever increasingly complex operational environment, intensified by the numerous types of mission/modes, number and type of targets, non-homogenous clutter and active interferers in the scene. Thus, the ability to adapt ones transmit waveform, to optimally suit the needs for a particular radar tasking and environment, becomes mandatory. This requirement brings with it a host of challenges to implement including the basic decision of what to transmit. In this dissertation, we discuss six original contributions, including the development of performance prediction models for constrained radar waveforms, that aid in the decision making process of an adaptive radar …

Go to article

Poly(Arylene Ether Sulfone)S With Ammonium Groups Located On Pendent Phenyl Sulfonyl Moieties For Anionic Exchange Membranes, Trevor I. Schumacher Jan 2016

Poly(Arylene Ether Sulfone)S With Ammonium Groups Located On Pendent Phenyl Sulfonyl Moieties For Anionic Exchange Membranes, Trevor I. Schumacher

Browse all Theses and Dissertations

A series of poly(aryl ether sulfone)s with varying percentages of ammonium groups, located on truly pendent positions, was prepared and characterized. The initial polymers were prepared by nucleophilic aromatic substitution (NAS) polycondensation reactions of varying ratios of 3,5-difluoro-4'-methyldiphenylsulfone and 4,4'-difluorodiphenylsulfone, with bisphenol-A as the nucleophilic reaction partner. The tolyl groups in the resulting polymers were subjected to radical bromination with N-bromosuccinimide, followed by amination with three different amines: trimethylamine, dimethylhexadecylamine, and N-methylimidazole. The polymers were characterized by 1H and 13C NMR spectroscopy, thermogravimetric analysis, and differential scanning calorimetry. With the exception of the 100% functionalized polymers, tough films were observed …

Go to article

Social Network Analysis And The Representation Of Female Students In Introductory Undergraduate Physics, Sarah Teresa Hierath Jan 2016

Social Network Analysis And The Representation Of Female Students In Introductory Undergraduate Physics, Sarah Teresa Hierath

Browse all Theses and Dissertations

Physics Education Research has begun to focus on the learning habits, success, and connections of students in physics classrooms using Social Network Analysis (SNA). SNA is an important tool in studying classroom dynamics because it can be used to map the social structure of a classroom's interactions and to aid in understanding how students work and study together. This study presents network diagrams, statistics, centrality measures, and conceptual understanding correlations for 7 different sections of introductory physics. Centrality measures were determined from a first and last week survey in which students were asked to indicate their study partners within the …

Go to article

Towards Best Practices For Crowdsourcing Ontology Alignment Benchmarks, Reihaneh Amini Jan 2016

Towards Best Practices For Crowdsourcing Ontology Alignment Benchmarks, Reihaneh Amini

Browse all Theses and Dissertations

Ontology alignment systems establish the semantic links between ontologies that enable knowledge from various sources and domains to be used by automated applications in many different ways. Unfortunately, these systems are not perfect. Currently, the results of even the best-performing automated alignment systems need to be manually verified in order to be fully trusted. Ontology alignment researchers have turned to crowdsourcing platforms such as Amazon's Mechanical Turk to accomplish this. However, there has been little systematic analysis of the accuracy of crowdsourcing for alignment verification and the establishment of best practices. In this work, we analyze the impact of the …

Go to article

A Structural Model Of Elementary Teachers' Knowledge, Beliefs, And Practices For Next Generation Science Teaching, Katahdin Abigail Cook Whitt Jan 2016

A Structural Model Of Elementary Teachers' Knowledge, Beliefs, And Practices For Next Generation Science Teaching, Katahdin Abigail Cook Whitt

Browse all Theses and Dissertations

The publication of the National Research Council's Framework for K-12 Science Education (2012) and the Next Generation Science Standards (NGSS Lead States, 2013) marked a turning point in science education characterized by a shift away from the idea that students should learn about a set of science facts and toward the idea that students should figure out core science ideas by solving problems and making sense of phenomena. To successfully realize the vision for science education that was articulated in the reform documents, teachers' science classroom practices will need to change, particularly at the elementary level. Science education research has …

Go to article

Correlating Innate Functional Recovery From Stroke Either With Stem Cell Proliferation And/Or Limb Rehabilitation, Devipriyanka Nagarajan Jan 2016

Correlating Innate Functional Recovery From Stroke Either With Stem Cell Proliferation And/Or Limb Rehabilitation, Devipriyanka Nagarajan

Browse all Theses and Dissertations

In the present study 10-12 month female rats were examined for functional recovery from stroke and this recovery was compared with the stem cell/progenitor cell proliferation in the brain (which was measured by Ki67). The cell proliferation indicated by Ki67 showed a 6 fold increase in control animals compared to the rehabilitation animals. The contralateral functional recovery in control animals were 46.6% and in the rehabilitation animals were 24.5%. The physical rehabilitation was carried out to determine if limb rehabilitation can promote greater functional recovery. The results showed that when the animals were made to over use their impaired limb …

Go to article

Examination Of A Post-Stroke Drug Treatment For Its Effect On Blood Brain Barrier Permeability, And Gene Expression Changes In The Peri-Infarct Region, Ankita Anil Patel Jan 2016

Examination Of A Post-Stroke Drug Treatment For Its Effect On Blood Brain Barrier Permeability, And Gene Expression Changes In The Peri-Infarct Region, Ankita Anil Patel

Browse all Theses and Dissertations

In this current study, we have investigated this a combination of fluoxetine, simvastatin and ascorbic acid administered daily beginning at 20-26 hours after stroke induction. We hope to understand therapeutic abilities by studying its effectiveness on the blood brain barrier permeability and gene expression changes of the microglial subtypes involved in neuro-inflammation and neurogenesis factors in the peri-infarct region. Our results indicate that S-enantiomer of fluoxetine may be more beneficial compared to the R-enantiomer. The S-enantiomer was effective in tightening the blood brain barrier in contrast to the R-enantiomer, in which the latter showed a greater Evans Blue dye permeability …

Go to article

Temporal Variation Of Mercury In Effluent From Two Municipal Wastewater Treatment Plants In Southwest Ohio, Heather Brittany Perusini Jan 2016

Temporal Variation Of Mercury In Effluent From Two Municipal Wastewater Treatment Plants In Southwest Ohio, Heather Brittany Perusini

Browse all Theses and Dissertations

Mercury (Hg) is a toxic metal that, once converted to methylmercury by microorganisms, bioaccumulates in aquatic food webs and poses a health risk to wildlife and humans who eat fish. Wastewater treatment plants (WWTPs) are a source of Hg to surface waters, but little is known about the temporal variability of Hg concentrations in effluent and efflux to aquatic systems. I quantified the concentration of Hg in effluent from the City of Dayton (Ohio) and Ford Road (Xenia, Ohio) WWTPs and examined temporal variability over monthly and hourly time scales as well as efficiency of Hg removal. Over a 13-month …

Go to article

Knowledge-Driven Implicit Information Extraction, Pathirage Dinindu Perera Jan 2016

Knowledge-Driven Implicit Information Extraction, Pathirage Dinindu Perera

Browse all Theses and Dissertations

Natural language is a powerful tool developed by humans over hundreds of thousands of years. The extensive usage, flexibility of the language, creativity of the human beings, and social, cultural, and economic changes that have taken place in daily life have added new constructs, styles, and features to the language. One such feature of the language is its ability to express ideas, opinions, and facts in an implicit manner. This is a feature that is used extensively in day to day communications in situations such as: 1) expressing sarcasm, 2) when trying to recall forgotten things, 3) when required to …

Go to article

Identifying Tweets With Implicit Entity Mentions, Adarsh Koruthu Alex Jan 2016

Identifying Tweets With Implicit Entity Mentions, Adarsh Koruthu Alex

Browse all Theses and Dissertations

Social networking sites like Twitter and Facebook have become a significant source of user-generated content in the past decade. Mining of this user-generated content has proved beneficial for a broad range of applications like Event Extraction, Document Retrieval, and Sentiment Analysis. Identifying entities is one of the major tasks that fuel important information for above tasks. Identification of entities is typically performed in two steps; Named Entity Recognition (NER) and Entity Linking. State of the art NER solutions focus on recognizing the entities that are mentioned explicitly in social media posts. However, entities are frequently mentioned implicitly in them. For …

Go to article

Gpu-Accelerated Feature Tracking, Alex Graves Jan 2016

Gpu-Accelerated Feature Tracking, Alex Graves

Browse all Theses and Dissertations

The motivation of this research is to prove that GPUs can provide significant speedup of long-executing image processing algorithms by way of parallelization and massive data throughput. This thesis accelerates the well-known KLT feature tracking algorithm using OpenCL and an NVidia GeForce GTX 780 GPU. KLT is a fast, efficient and accurate feature tracker but can easily suffer from low frame rates when tracking many features in an HD video sequence. This research explains how KLT could benefit from GPGPU programming and provides the corresponding OpenCL implementation. Additionally, various optimization techniques are emphasized to further boost GPU performance. The experiments …

Go to article

Framework For Semantic Integration And Scalable Processing Of City Traffic Events, Surendra Brahma Marupudi Jan 2016

Framework For Semantic Integration And Scalable Processing Of City Traffic Events, Surendra Brahma Marupudi

Browse all Theses and Dissertations

Intelligent traffic management requires analysis of a large volume of multimodal data from diverse domains. For the development of intelligent traffic applications, we need to address diversity in observations from physical sensors which give weather, traffic flow, parking information; we also need to do the same with social media, which provides live commentary of various events in a city. The extraction of relevant events and the semantic integration of numeric values from sensors, unstructured text from Twitter, and semi- structured data from city authorities is a challenging physical-cyber-social data integration problem. In order to address the challenge of both scalability …

Go to article

Retail Facility Design Considering Product Exposure, Corinne H. Mowrey Jan 2016

Retail Facility Design Considering Product Exposure, Corinne H. Mowrey

Browse all Theses and Dissertations

Retail store's layout affects a shopper's visual experience and correspondingly the time spent in the store, navigation through the aisles, and allocation of attention and money across departments and categories. We contend that alternate rack layouts allow for more of a rack's facing to appear in the shopper's visual field. In this work we focus on the following two questions: (i) what impact does a given rack layout have on how much of a rack display is exposed to a shopper? (ii) what rack layouts maximize exposure to a shopper? To address the first question, we introduce a set of …

Go to article

A Fractal-Based Mathematical Model For Cancellous Bone Growth Considering The Hierarchical Nature Of Bone, Stephanie Marie Suhr Jan 2016

A Fractal-Based Mathematical Model For Cancellous Bone Growth Considering The Hierarchical Nature Of Bone, Stephanie Marie Suhr

Browse all Theses and Dissertations

The hierarchical structure of bone alone is not comprehensive enough to provide morphological explanation of how the size and arrangement of the trabeculae within cancellous bone affect load distribution, particularly concerning deterioration of bone in elderly patients. The collagen network and hydroxyapatite play a large role in defining the shape of trabeculae in cancellous bone despite that the arrangement and size is seemingly random. The growth of plates and rods in cancellous bone is mainly due to loading and stress lines within the bone, but mathematical predictive models can be developed using fractal analysis to show how bone may grow …

Go to article

Application Of Time-Frequency Analysis To Characterize Gas Shadows From The Clinton Interval In Ohio Seismic Reflection Data, Fangzhou Yan Jan 2016

Application Of Time-Frequency Analysis To Characterize Gas Shadows From The Clinton Interval In Ohio Seismic Reflection Data, Fangzhou Yan

Browse all Theses and Dissertations

The Smoothed Pseudo Wigner-Ville Distribution (SPWVD) is one method to simultaneously resolve time series in both time and frequency domains, allowing determination of frequency variation with time in non-stationary signals. Also, SPWVD reduces the cross-term interference. This analysis was applied to stacked, migrated seismic reflection data from Ohio to characterize gas shadows produced by known and potential gas reservoirs in the Clinton interval. In northeast Ohio, the Clinton interval is identified as occurring immediately beneath the Dayton Limestone, which is known as the driller’s Packer Shell in the subsurface. The analysis was first applied to a seismic reflection line acquired …

Go to article

Functional Characterization Of Cancer-Related Mutations Of Erk3, Hadel Mohammed Alsaran Jan 2016

Functional Characterization Of Cancer-Related Mutations Of Erk3, Hadel Mohammed Alsaran

Browse all Theses and Dissertations

Extracellular signal-regulated kinase 3 (ERK3) is an atypical member of the mitogen-activated protein kinase (MAPK) family. Recent studies have shown that ERK3 is highly upregulated in multiple cancers, such as lung cancer and colon cancer. Importantly, ERK3 promotes cancer cell migration and invasion by phosphorylating steroid receptor activator 3 (SRC-3), hence upregulating pro-invasive matrix metalloproteinase genes. While the link between ERK3 and cancers has been recognized, little is known about ERK3 mutations in cancer progression. In this study, we have investigated ERK3 mutations on arginine 64 (arginine 64 mutated to cysteine or histidine, R64C or R64H) and leucine 290 (leucine …

Go to article

Correlations Between Introductory Students’ Attitudes About Physics And Conceptual Understanding, Raym Alzahrani Jan 2016

Correlations Between Introductory Students’ Attitudes About Physics And Conceptual Understanding, Raym Alzahrani

Browse all Theses and Dissertations

The purpose of this study is to measure correlations between the students’ incoming attitudes, beliefs and expectations about physics and their conceptual understanding. The study presents a profile of the attitudes and beliefs for Wright State University students who enrolled in calculus-based General Physics I courses during academic years 2014-2015 and 2015-2016. Students’ initial and final attitudes, measured using the CLASS, are correlated with initial and final conceptual gain, measured using the Force Concept Inventory. Students’ initial attitudes (Opre) was correlated with students’ gain (FCIgain) in many sections. Correlations between students’ final attitudes (Opost) and their conceptual understanding (FCIpost), reported …

Go to article

First Prev Next Last