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The Pathways To Mental Health Care Of First-Episode Psychosis Patients: A Systematic Review., Kelly K. Anderson, Rebecca Fuhrer, Ashok K. Malla Oct 2010

The Pathways To Mental Health Care Of First-Episode Psychosis Patients: A Systematic Review., Kelly K. Anderson, Rebecca Fuhrer, Ashok K. Malla

Epidemiology and Biostatistics Publications

BACKGROUND: Although there is agreement on the association between delay in treatment of psychosis and outcome, less is known regarding the pathways to care of patients suffering from a first psychotic episode. Pathways are complex, involve a diverse range of contacts, and are likely to influence delay in treatment. We conducted a systematic review on the nature and determinants of the pathway to care of patients experiencing a first psychotic episode.

METHOD: We searched four databases (Medline, HealthStar, EMBASE, PsycINFO) to identify articles published between 1985 and 2009. We manually searched reference lists and relevant journals and used forward citation …


A Mi'kmaq First Nation Cosmology: Investigating The Practice Of Contemporary Aboriginal Traditional Medicine In Dialogue With Counselling – Toward An Indigenous Therapeutics, Kisiku Sa'qawei Paq'tism Randolph Bowers Sep 2010

A Mi'kmaq First Nation Cosmology: Investigating The Practice Of Contemporary Aboriginal Traditional Medicine In Dialogue With Counselling – Toward An Indigenous Therapeutics, Kisiku Sa'qawei Paq'tism Randolph Bowers

Aboriginal Policy Research Consortium International (APRCi)

This paper explores from a Mi’kmaq and Aboriginal standpoint foundational knowledge in Indigenous therapeutics. Based on an eco-social-psycho-spiritual way of working, the article proposes Indigenous cultural models that open a window to a rich cultural repository of meanings associated with Indigenous cosmology, ontology and epistemology. The three layers of meaning, theory and practice within the symbolic ‘Medicine Lodge’ or ‘Place of The Dreaming’ give rise to ways of working that are deeply integrative and wholistic. These forms of Indigenous theory and practice have much to offer the counselling and complimentary health professions.


A Behavioral Genetic Study Of Relationships Between Humor Styles And The Six Hexaco Personality Factors, Livia Veselka, Julie A. Schermer, Rod A. Martin, Lynn F. Cherkas, Tim D. Spector, Philip A. Vernon Aug 2010

A Behavioral Genetic Study Of Relationships Between Humor Styles And The Six Hexaco Personality Factors, Livia Veselka, Julie A. Schermer, Rod A. Martin, Lynn F. Cherkas, Tim D. Spector, Philip A. Vernon

Management and Organizational Studies Publications

In this study, four humor styles (affiliative, self-enhancing, aggressive, self-defeating) were assessed in conjunction with a measure of the HEXACO model of personality, in order to gain greater insight into the etiology of these humor styles, and to situate them better in the framework of human personality. Participants were 664 monozygotic twin pairs and 522 dizygotic twin pairs from the United Kingdom who completed the Humor Styles Questionnaire and the HEXACO Personality Inventory. Univariate behavioral genetic analyses of the HEXACO revealed that individual differences in all of its dimensions were entirely attributable to additive genetic and non-shared environmental factors. Significant …


Concurrent Associations Among Sleep Problems, Indicators Of Inadequate Sleep, Psychopathology, And Shared Risk Factors In A Population-Based Sample Of Healthy Ontario Children, J. Aimée Coulombe, Graham J. Reid, Michael H. Boyle, Yvonne Racine Aug 2010

Concurrent Associations Among Sleep Problems, Indicators Of Inadequate Sleep, Psychopathology, And Shared Risk Factors In A Population-Based Sample Of Healthy Ontario Children, J. Aimée Coulombe, Graham J. Reid, Michael H. Boyle, Yvonne Racine

Paediatrics Publications

Objectives Examine the contribution of sleep problems and indicators of inadequate sleep to psychopathology among children after accounting for shared risk and comorbid psychopathology. Methods Secondary analyses of cross-sectional data on 4- to 11-year-old (N = 1,550) children without chronic illness or developmental delay or disability. Parents provided information about sleep problems, indicators of inadequate sleep, symptoms of psychopathology, and risk factors for psychopathology. Teachers provided information about indicators of inadequate sleep and symptoms of psychopathology. Results Adjusting for risk factors and comorbid psychopathology, sleeping more than other children was related to parent-rated aggression. Nightmares and trouble sleeping were related …


Neural Reuse: A Fundamental Organizational Principle Of The Brain, Michael Anderson Aug 2010

Neural Reuse: A Fundamental Organizational Principle Of The Brain, Michael Anderson

Brain and Mind Institute Researchers' Publications

An emerging class of theories concerning the functional structure of the brain takes the reuse of neural circuitry for various cognitive purposes to be a central organizational principle. According to these theories, it is quite common for neural circuits established for one purpose to be exapted (exploited, recycled, redeployed) during evolution or normal development, and be put to different uses, often without losing their original functions. Neural reuse theories thus differ from the usual understanding of the role of neural plasticity (which is, after all, a kind of reuse) in brain organization along the following lines: According to neural reuse, …


Multiple Mechanisms Of Consciousness: The Neural Correlates Of Emotional Awareness., Jayna M Amting, Steven G Greening, Derek G V Mitchell Jul 2010

Multiple Mechanisms Of Consciousness: The Neural Correlates Of Emotional Awareness., Jayna M Amting, Steven G Greening, Derek G V Mitchell

Brain and Mind Institute Researchers' Publications

Emotional stimuli, including facial expressions, are thought to gain rapid and privileged access to processing resources in the brain. Despite this access, we are conscious of only a fraction of the myriad of emotion-related cues we face everyday. It remains unclear, therefore, what the relationship is between activity in neural regions associated with emotional representation and the phenomenological experience of emotional awareness. We used functional magnetic resonance imaging and binocular rivalry to delineate the neural correlates of awareness of conflicting emotional expressions in humans. Behaviorally, fearful faces were significantly more likely to be perceived than disgusted or neutral faces. Functionally, …


Somatic Symptom Overlap In Beck Depression Inventory-Ii Scores Following Myocardial Infarction., Brett D Thombs, Roy C Ziegelstein, Louise Pilote, David J A Dozois, Aaron T Beck, Keith S Dobson, Samantha Fuss, Peter De Jonge, Sherry L Grace, Donne E Stewart, Johan Ormel, Susan E Abbey Jul 2010

Somatic Symptom Overlap In Beck Depression Inventory-Ii Scores Following Myocardial Infarction., Brett D Thombs, Roy C Ziegelstein, Louise Pilote, David J A Dozois, Aaron T Beck, Keith S Dobson, Samantha Fuss, Peter De Jonge, Sherry L Grace, Donne E Stewart, Johan Ormel, Susan E Abbey

Psychology Publications

BACKGROUND: Depression measures that include somatic symptoms may inflate severity estimates among medically ill patients, including those with cardiovascular disease.

AIMS: To evaluate whether people receiving in-patient treatment following acute myocardial infarction (AMI) had higher somatic symptom scores on the Beck Depression Inventory-II (BDI-II) than a non-medically ill control group matched on cognitive/affective scores.

METHOD: Somatic scores on the BDI-II were compared between 209 patients admitted to hospital following an AMI and 209 psychiatry out-patients matched on gender, age and cognitive/affective scores, and between 366 post-AMI patients and 366 undergraduate students matched on gender and cognitive/affective scores.

RESULTS: Somatic symptoms …


Deficits In Attention To Emotional Stimuli Distinguish Youth With Severe Mood Dysregulation From Youth With Bipolar Disorder., Brendan A Rich, Melissa A Brotman, Daniel P Dickstein, Derek G V Mitchell, R James R Blair, Ellen Leibenluft Jul 2010

Deficits In Attention To Emotional Stimuli Distinguish Youth With Severe Mood Dysregulation From Youth With Bipolar Disorder., Brendan A Rich, Melissa A Brotman, Daniel P Dickstein, Derek G V Mitchell, R James R Blair, Ellen Leibenluft

Brain and Mind Institute Researchers' Publications

Studying attention in the context of emotional stimuli may aid in differentiating pediatric bipolar disorder (BD) from severe mood dysregulation (SMD). SMD is characterized by chronic irritability, arousal, and hyper-reactivity; SMD youth frequently receive a BD diagnosis although they do not meet DSM-IV criteria for BD because they lack manic episodes. We compared 57 BD (14.4 +/- 2.9 years old, 56% male), 41 SMD (12.6 +/- 2.6 years old, 66% male), and 33 control subjects (13.7 +/- 2.5 years old, 52% male) using the Emotional Interrupt task, which examines how attention is impacted by positive, negative, or neutral distracters. We …


Women's Perception Of Science: Theory And Practice, Rashida A. Khanum Jun 2010

Women's Perception Of Science: Theory And Practice, Rashida A. Khanum

XIV IAPh Symposium 2010

This presentation is part of the Science and Values: Global Perspectives track.

Science is very much recognized as giving new life to mankind and this new life means advancement or progress. Science is utilitarian because its discoveries and inventions satisfy human needs. Feminists perceive these impacts of science and technology though there exists a negative side of science and technology about which feminists are critical. Sal Restivo blames science as responsible for generating new social problems, which Sandra Harding accounted positively. Harding evaluates science and technology as both progressive and regressive.1 I shall analyze Harding’s feminist views of science and …


“We Are Not Disposable“: “Psychiatric”/Psycho-Social Disabilities, Survivor Knowledge, And Audre Lorde’S Critique Of Market Fundamentalism, Carol J. Moeller Jun 2010

“We Are Not Disposable“: “Psychiatric”/Psycho-Social Disabilities, Survivor Knowledge, And Audre Lorde’S Critique Of Market Fundamentalism, Carol J. Moeller

XIV IAPh Symposium 2010

This presentation is part of the Disability and Dependence track.

Audre Lorde: “In a society where the good is defined in terms of profit rather than in terms of human need, there must always be some group of people who, through systematized oppression, can be made to feel surplus, to occupy the position of the dehumanized inferior.”

People with disabilities, including “psychiatric”/psycho-social diversities, may live in ways that reject hegemonic standards of personhood, societal membership, and contribution. Such dominant norms tend to value people for how “productive” they are, framing disabled and other marginalized people as a drain on public …


Accountability Or Attestation? An Assessment Of Butler’S Ethical Subject With The Help Of Ricoeur, Annemie Halsema Jun 2010

Accountability Or Attestation? An Assessment Of Butler’S Ethical Subject With The Help Of Ricoeur, Annemie Halsema

XIV IAPh Symposium 2010

This presentation is part of the Ethical and Epistemic Choices: New Approaches track.

In Giving an Account of Oneself (2005) Judith Butler investigates the possibility of ethics starting from a poststructuralist subject position. Whereas in earlier works, with concepts such as “performativity,” Butler put the ethical and critical capacities of the subject into perspective, works such as Giving an Account of Oneself, Precarious Life (2004) and to some extent Antigone’s Claim (2000), give the impression of a “turn” to ethics.

In the paper I will evaluate the notion of the ethical subject that Butler uses in these works by confronting …


The Development Of Metaphorical Language Comprehension In Typical Development And In Williams Syndrome, Michael S.C. Thomas, Mike Van Duuren, Harry R.M. Purser, Denis Mareschal, Daniel Ansari, Annette Karmiloff-Smith Jun 2010

The Development Of Metaphorical Language Comprehension In Typical Development And In Williams Syndrome, Michael S.C. Thomas, Mike Van Duuren, Harry R.M. Purser, Denis Mareschal, Daniel Ansari, Annette Karmiloff-Smith

Paediatrics Publications

The domain of figurative language comprehension was used to probe the developmental relation between language and cognition in typically developing individuals and individuals with Williams syndrome. Extending the work of Vosniadou and Ortony, the emergence of nonliteral similarity and category knowledge was investigated in 117 typically developing children between 4 and 12 years of age, 19 typically developing adults, 15 children with Williams syndrome between 5 and 12 years of age, and 8 adults with Williams syndrome. Participants were required to complete similarity and categorization statements by selecting one of two words (e.g., either "The sun is like ___" or …


Serum Lipids And Suicidality In Early Psychosis: Is There A Connection? A Preliminary Study, Amresh Srivastava, Megan Johnston, Lenore Purde, Robbie Campbell May 2010

Serum Lipids And Suicidality In Early Psychosis: Is There A Connection? A Preliminary Study, Amresh Srivastava, Megan Johnston, Lenore Purde, Robbie Campbell

Psychiatry Presentations

No abstract provided.


Psychoendocrinology (Thyroid Hormone) And Early Psychosis: Preliminary Findings, Amresh Srivastava, Megan Johnston, Lenore Purde, Robbie Campbell May 2010

Psychoendocrinology (Thyroid Hormone) And Early Psychosis: Preliminary Findings, Amresh Srivastava, Megan Johnston, Lenore Purde, Robbie Campbell

Psychiatry Presentations

No abstract provided.


To Be Or Not To Be': Education For Clinical Practice In Risk Assessment Of Suicide Behavior, Amresh Srivastava, Megan Johnstom May 2010

To Be Or Not To Be': Education For Clinical Practice In Risk Assessment Of Suicide Behavior, Amresh Srivastava, Megan Johnstom

Data and Test Instruments

Clinical practice of psychiatry has acquired role and responsibility which goes far beyond traditional expectations .Incident of suicide, particularly, is considered a high liability for then professionals, organizations and the consumer. It also remains a clinical issue which examines can we prevent suicide which in the system of care. Studies have shown about 1 in 6 psychologists or psychiatrist are likely to loose a patient due to suicide in a mean duration of 18-20 years practice. Repeatedly it has demonstrated that clinical skill training for risk assessment is the necessary for all professionals not only in mental health but also …


To Be Or Not To Be: Education For Clinical Decisions In Risk Assessment Of Suicide Behavior, Amresh Srivastava, Megan Johnston May 2010

To Be Or Not To Be: Education For Clinical Decisions In Risk Assessment Of Suicide Behavior, Amresh Srivastava, Megan Johnston

Data and Test Instruments

Clinical practice of psychiatry has acquired role and responsibility which goes far beyond traditional expectations .Incident of suicide, particularly, is considered a high liability for then professionals, organizations and the consumer. It also remains a clinical issue which examines can we prevent suicide which in the system of care. Studies have shown about 1 in 6 psychologist or psychiatrist are likely to loose a patient due to suicide in a mean duration of 18-20 years practice. Repeatedly it has demonstrated that clinical skill training for risk assessment is the necessary for all professionals not only in mental health but also …


Should 'Risk Syndrome Of Psychosis' Be Included In Dsm V As A Diagnosis? A Road Towards Preventive Psychiatry, Amresh Srivastava May 2010

Should 'Risk Syndrome Of Psychosis' Be Included In Dsm V As A Diagnosis? A Road Towards Preventive Psychiatry, Amresh Srivastava

Psychiatry Presentations

No abstract provided.


Enhancing Risk Assessment Across Mental Health Services, Amresh Srivastava, Megan Johnston, Charles Nelson May 2010

Enhancing Risk Assessment Across Mental Health Services, Amresh Srivastava, Megan Johnston, Charles Nelson

Psychiatry Presentations

No abstract provided.


Motor Output Evoked By Subsaccadic Stimulation Of Primate Frontal Eye Fields., Brian D Corneil, James K Elsley, Benjamin Nagy, Sharon L Cushing Mar 2010

Motor Output Evoked By Subsaccadic Stimulation Of Primate Frontal Eye Fields., Brian D Corneil, James K Elsley, Benjamin Nagy, Sharon L Cushing

Brain and Mind Institute Researchers' Publications

In addition to its role in shifting the line of sight, the oculomotor system is also involved in the covert orienting of visuospatial attention. Causal evidence supporting this premotor theory of attention, or oculomotor readiness hypothesis, comes from the effect of subsaccadic threshold stimulation of the oculomotor system on behavior and neural activity in the absence of evoked saccades, which parallels the effects of covert attention. Here, by recording neck-muscle activity from monkeys and systematically titrating the level of stimulation current delivered to the frontal eye fields (FEF), we show that such subsaccadic stimulation is not divorced from immediate motor …


Seasonal Hippocampal Plasticity In Food-Storing Birds., David F Sherry, Jennifer S Hoshooley Mar 2010

Seasonal Hippocampal Plasticity In Food-Storing Birds., David F Sherry, Jennifer S Hoshooley

Psychology Publications

Both food-storing behaviour and the hippocampus change annually in food-storing birds. Food storing increases substantially in autumn and winter in chickadees and tits, jays and nutcrackers and nuthatches. The total size of the chickadee hippocampus increases in autumn and winter as does the rate of hippocampal neurogenesis. The hippocampus is necessary for accurate cache retrieval in food-storing birds and is much larger in food-storing birds than in non-storing passerines. It therefore seems probable that seasonal change in caching and seasonal change in the hippocampus are causally related. The peak in recruitment of new neurons into the hippocampus occurs before birds …


Theta-Activity In Anterior Cingulate Cortex Predicts Task Rules And Their Adjustments Following Errors, Thilo Womelsdorf, Kevin Johnston, Martin Vinck, Stefan Everling Mar 2010

Theta-Activity In Anterior Cingulate Cortex Predicts Task Rules And Their Adjustments Following Errors, Thilo Womelsdorf, Kevin Johnston, Martin Vinck, Stefan Everling

Brain and Mind Institute Researchers' Publications

Accomplishing even simple tasks depend on neuronal circuits to configure how incoming sensory stimuli map onto responses. Controlling these stimulus-response (SR) mapping rules relies on a cognitive control network comprising the anterior cingulate cortex (ACC). Single neurons within the ACC convey information about currently relevant SR mapping rules and signal unexpected action outcomes, which can be used to optimize behavioral choices. However, its functional significance and the mechanistic means of interaction with other nodes of the cognitive control network remain elusive and poorly understood. Here, we report that core aspects of cognitive control are encoded by rhythmic theta-band activity within …


From Infant Attachment Security To Mother-Child Emotion Dialogues: Understanding Emotion Communication In The Early Years, Celia Hsiao, Greg Moran, Nina Koren-Karie Mar 2010

From Infant Attachment Security To Mother-Child Emotion Dialogues: Understanding Emotion Communication In The Early Years, Celia Hsiao, Greg Moran, Nina Koren-Karie

Psychology Presentations

Researchers have become increasingly interested in understanding the developmental trajectory of attachment security from the preverbal infancy period to later verbal stages. One approach that has received much theoretical and empirical support is to examine the capacity of children and their mothers to work together in co-constructing narratives around personal and emotional events(Bretherton, 1990; Oppenheim, Koren-Karie & Sagi-Schwartz, 2007). It has been suggested (Oppenheim & Koren-Karie, 2009) that open communication between a secure dyad during infancy, involving primarily non-verbal signals, provides the basis for an open and fluid communication style in the preschool years. The secure child feels confident in …


Maternal State Of Mind: How Does It Impact The Ability To Flexibly Adjust To Siblings' Needs?, Kathleen Anne O'Connor, Greg Moran, David R. Pederson, Sandi Bento Mar 2010

Maternal State Of Mind: How Does It Impact The Ability To Flexibly Adjust To Siblings' Needs?, Kathleen Anne O'Connor, Greg Moran, David R. Pederson, Sandi Bento

Psychology Presentations

PURPOSE: To investigate the impact of maternal state of mind on the ability to adapt interactive behavior and perceptions of attachment behaviour across siblings.

RESULTS: Maternal sensitivity and perceptions of siblings’ attachment behavior were highly correlated across children of non-Autonomous mothers, but not Autonomous mothers. Non- Autonomous mothers behaved similarly on eight domains of interactive behaviour, while Autonomous mothers behaved similarly on only two.

CONCLUSION: These findings suggest that maternal state of mind is implicated in the ability to flexibly adapt interactive style and relationship-specific attachment perceptions across siblings.


The Continuity Of Attachment Development From Infancy To Toddlerhood: The Role Of Maternal Sensitivity, Ya F. Xue, Greg Moran, David R. Pederson, Sandi Bento Mar 2010

The Continuity Of Attachment Development From Infancy To Toddlerhood: The Role Of Maternal Sensitivity, Ya F. Xue, Greg Moran, David R. Pederson, Sandi Bento

Psychology Presentations

The patterns of attachment between infants and mothers have far-reaching consequences for infants’ development; infants with secure attachments fare better socially and emotionally than those with non-secure attachments (Deklyen & Greenberg,2008).

Theory suggests that differences in attachment quality result from differences in mother-child interactions: secure attachment results from a history of sensitive interactions and non-secure attachment from insensitive interaction.

Since the attachment security is held to be a product of the quality of interactions; a change in the quality of interactions should theoretically lead to a change in attachment quality. Thus, a child in a secure relationship later encountering insensitive …


The Development Of Disorganized Attachment In Infants Of Adult And Adolescent Mothers, Tara Morley, Greg Moran, David Pederson, Sandi Bento, Heidi Bailey Mar 2010

The Development Of Disorganized Attachment In Infants Of Adult And Adolescent Mothers, Tara Morley, Greg Moran, David Pederson, Sandi Bento, Heidi Bailey

Psychology Presentations

Attachment theory proposes that maternal sensitivity is the main developmental determinant of Organized attachment relationships (Ainsworth Blehar, Waters & Wall, 1978; DeWolff & van IJzendoorn, 1997); In contrast, Disorganized attachment relationships are held to be the product of frightened, frightening or atypical maternal behaviour (Lyons-Ruth, Bronfman, & Parson, 1999; Main & Hesse, 1990).

However, recent research has identified associations between low levels of maternal sensitivity and Disorganized attachment in high-risk populations (Bernier & Meins, 2008; Moran, Forbes, Evans, Tarabulsy, & Madigan, 2008; van IJzendoorn, Scheungel & Bakermans-Kranenburg, 1999); This raises the possibility that maternal sensitivity may contribute to the development …


Beyond Sensitivity: Patterns Of Maternal Interaction In Secure Vs. Non-Secure Attachment Relationships, Tara Morley, Ya Xue, Kathleen O'Connor, Greg Moran, David Pederson, Sandi Bento Mar 2010

Beyond Sensitivity: Patterns Of Maternal Interaction In Secure Vs. Non-Secure Attachment Relationships, Tara Morley, Ya Xue, Kathleen O'Connor, Greg Moran, David Pederson, Sandi Bento

Psychology Presentations

Attachment theory proposes that the sensitivity of a mother’s interactions with her child is the main developmental determinant of the quality of their attachment relationship (Ainsworth et al., 1978; De Wolff & van Ijzendoorn, 1997).

Empirical findings have generally supported this assertion; however, the strength of this association remains a matter of debate as the results of empirical findings have been highly variable (Atkinson et al., 2000; DeWolff & van IJzendoorn, 1997).

Several researchers have suggested that assessing maternal behaviour as a single global dimension may fail to capture important variation in the quality of interactions that influence the developing …


Exploring The Development Of Attachment In Infants Of Adult And Adolescent Mothers, Tara Morley, Greg Moran, David Pederson, Heidi Bailey Mar 2010

Exploring The Development Of Attachment In Infants Of Adult And Adolescent Mothers, Tara Morley, Greg Moran, David Pederson, Heidi Bailey

Psychology Presentations

While many studies have looked at the development of attachment relationships for adult and adolescent mothers separately, few studies have directly compared these two groups in a single study

The current study further explored the origins of attachment relationships for adolescent mothers and their infants by directly comparing the development of these processes with adult mothers and their infants

The hypothesis that differences in the distributions of attachment classifications among these two populations is a result of low levels of sensitivity has yet to be tested in a mediational analysis

The current study will test a model whereby differences in …


Running Enhances Spatial Pattern Separation In Mice., David J Creer, Carola Romberg, Lisa M Saksida, Henriette Van Praag, Timothy J Bussey Feb 2010

Running Enhances Spatial Pattern Separation In Mice., David J Creer, Carola Romberg, Lisa M Saksida, Henriette Van Praag, Timothy J Bussey

Brain and Mind Institute Researchers' Publications

Increasing evidence suggests that regular exercise improves brain health and promotes synaptic plasticity and hippocampal neurogenesis. Exercise improves learning, but specific mechanisms of information processing influenced by physical activity are unknown. Here, we report that voluntary running enhanced the ability of adult (3 months old) male C57BL/6 mice to discriminate between the locations of two adjacent identical stimuli. Improved spatial pattern separation in adult runners was tightly correlated with increased neurogenesis. In contrast, very aged (22 months old) mice had impaired spatial discrimination and low basal cell genesis that was refractory to running. These findings suggest that the addition of …


Interaction Between 5-Httlpr And Bdnf Val66met Polymorphisms On Hpa Axis Reactivity In Preschoolers, Lea R. Dougherty, Daniel N. Klein, Eliza Congdon, Turhan Canli, Elizabeth P. Hayden Feb 2010

Interaction Between 5-Httlpr And Bdnf Val66met Polymorphisms On Hpa Axis Reactivity In Preschoolers, Lea R. Dougherty, Daniel N. Klein, Eliza Congdon, Turhan Canli, Elizabeth P. Hayden

Paediatrics Publications

This study examined whether the interaction between the serotonin transporter promoter region (5-HTTLPR) and brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms was associated with hypothalamic-pituitary-adrenal (HPA) axis reactivity to stress. A community sample of 144 preschool-aged children was genotyped and exposed to stress-inducing laboratory tasks. Salivary cortisol was obtained at four time points during a standardized laboratory assessment before and after stressors involving separation from a parent and frustrating tasks. Children homozygous for the short-5-HTTLPR allele and carrying the Met-BDNF allele evidenced a significantly lower initial level of cortisol, followed by a positive increase in cortisol in response to the laboratory …


What Do We Know About People Who Kill Themselves: A Trajectory For Prevention In Developing Countries., Amresh Srivastava, Megan Johnston Jan 2010

What Do We Know About People Who Kill Themselves: A Trajectory For Prevention In Developing Countries., Amresh Srivastava, Megan Johnston

Data and Test Instruments

Abstract: Lecture Title: What do we know about people who kill themselves: A trajectory for prevention in Developing Countries. Amresh Shrivastava 1, Megan Johnston 2 Address: 1. Department of Psychiatry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada; Lawson Health Research Institute, London, Ontario, Canada); Mental Health Foundation of India (PRERANA Charitable Trust) 209 Shivkripa Complex, Gokhale Road, Thane, Mumbai, Maharashtra, India 400 602 (Present Address: Regional Mental Health Care, 467 Sunset Drive, St. Thomas, Ontario, Canada N5H 3V9; 2. Department of Psychology, University of Toronto. About one million people die due to suicide …