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Articles 1561 - 1590 of 1943
Full-Text Articles in Entire DC Network
Metallothionein Gene Expression In Human Breast Cancer, Volkan Gurel
Metallothionein Gene Expression In Human Breast Cancer, Volkan Gurel
Graduate Theses, Dissertations, and Problem Reports (ETD)
Metallothioneins (MT) are a family of low molecular weight (6 kDa) cysteine rich proteins that participate in a variety of functions such as detoxification of heavy metals and homeostasis of essential metals. They can also act as scavengers of free radicals. MT-1 and 2 isoforms are ubiquitously expressed, whereas the expression of the third isoform is limited to the neural tissue. In the PC-3 prostate cancer cell line, MT-3 expression has been shown to inhibit cell growth and increase drug resistance. The goal of the present study was to determine if MT-3 overexpression would influence the growth of human breast …
Recreational Opportunities And Health Status In West Virginia, Yoav Sneh
Recreational Opportunities And Health Status In West Virginia, Yoav Sneh
Graduate Theses, Dissertations, and Problem Reports (ETD)
Over half of all Americans are considered to be physically inactive and/or obese, leading to significant individual and societal costs. This study investigates the link between recreational supply and health status for West Virginia. Using spatial econometric techniques, this study provides solid evidence that the demand for health care is positively associated with physical inactivity rates, and that physical inactivity rates are inversely related to the supply of recreational opportunities. When promoting the importance of physical activity as preventative health care, policy makers should consider the provision of recreational opportunities as a means to overcome sedentary behaviors.
Dietary Factors Influencing Iron Status Among Wic Participants Ages 6--24 Months, Marci Stayner Cannon
Dietary Factors Influencing Iron Status Among Wic Participants Ages 6--24 Months, Marci Stayner Cannon
Graduate Theses, Dissertations, and Problem Reports (ETD)
Iron deficiency is a nationwide concern. Dietary strategies issued by national organizations, aim to help prevent childhood iron deficiency. This study examined the relationship of dietary factors with iron status in WIC participants 6--24 months. This was a cross-sectional study of 50 rural infants and toddlers.;Iron deficiency was determined from one blood sample analyzed for serum ferritin (SF) and transferrin saturation (TS). Iron deficiency was defined as SF ≤ 15 ug/dL and TS ≤ 15%. Two, 24-hour dietary recalls were collected. Stepwise logistic regression was used to evaluate factors predictive of iron status.;Thirteen children (26%) were iron deficient. Iron status …
Influence Of Sward Height, Daily Timing Of Concentrate Supplementation And Grazing Time Management On Pasture Utilization Of Lactating Beef Cows, Ondieki James Gekara
Influence Of Sward Height, Daily Timing Of Concentrate Supplementation And Grazing Time Management On Pasture Utilization Of Lactating Beef Cows, Ondieki James Gekara
Graduate Theses, Dissertations, and Problem Reports (ETD)
To establish the effect of sward height, concentrate feeding time and grazing time management on performance of grazing cattle, thirty-two cross-bred beef (24 Angus and 8 Hereford) cows (632 kg BW) and calves (104 kg BW) were grouped by weight and calving date. They were randomly assigned to two sward height (SH) treatments (4 to 8 or 8 to 12 cm), replicated four times. The cows were fed a concentrate supplement (4.1 kg DM·cow -1·d-1) in the AM at 0700 h or PM at 1800 h (T), and either restricted to 12 h/d grazing (0700 to 1900 h) or unrestricted …
Regulation Of P-Glycoprotein And Abcp Transporters, Dhanashri Ramkrishna Kolwankar
Regulation Of P-Glycoprotein And Abcp Transporters, Dhanashri Ramkrishna Kolwankar
Graduate Theses, Dissertations, and Problem Reports (ETD)
The placenta plays an important role in modulating xenobiotic passage from mother to fetus. Smoking is known to induce cytochrome P450 1Al (CYP1A1) expression in the placenta, however its effect on P-glycoprotein (P-gp) and ABC transporter in placenta (ABCP) levels in placenta is not known. In-vitro studies in hepatocytes have reported induction of P-gp mRNA by some polycyclic aromatic hydrocarbons. To examine whether smoking can affect placental P-gp and ABCP, their expression and activity were determined in placentas from smokers and non-smokers. Uptake of [3H]-vinblastine and [3H]-mitoxantrone was used to measure P-gp and ABCP function, respectively and CYP1A1 activity (positive …
Meeting The Challenges Of Pasture-Finished Beef, Edward Barrow Rayburn
Meeting The Challenges Of Pasture-Finished Beef, Edward Barrow Rayburn
Faculty & Staff Scholarship
WVU-Extension fact sheet
Region Vii Workforce Investment Area Socio-Economic Characteristics Of Youth, George Hammond, Christiadi
Region Vii Workforce Investment Area Socio-Economic Characteristics Of Youth, George Hammond, Christiadi
Bureau of Business & Economic Research
No abstract provided.
A Survey Analysis Of Participation In A Community Forest Management In Nepal, Vishakha Maskey, Tesfa Gebremedhin, Timothy J. Dalton
A Survey Analysis Of Participation In A Community Forest Management In Nepal, Vishakha Maskey, Tesfa Gebremedhin, Timothy J. Dalton
Regional Research Institute Working Papers
The main objective of the study is to determine which socio-economic factors affect levels of individual participation in the “Ludi-damgade” community forest. The empirical evidence for participation as a function of social status is obtained by using an ordered probit model. The model also estimates the marginal effects of socio-economic factors on different levels of participation suggesting how per unit change in such socioeconomic characters affects the level of participation. Results from the two-stage least squares model also verify that participation in forest management determines the level of benefits received from the community forest. The study suggests that participation in …
Prediction Of Treatment Dropouts From Outpatient Substance Abuse Rehabilitation: A Discriminant Analysis., Phyllis J. Harner-Neer
Prediction Of Treatment Dropouts From Outpatient Substance Abuse Rehabilitation: A Discriminant Analysis., Phyllis J. Harner-Neer
Graduate Theses, Dissertations, and Problem Reports (ETD)
Significant research literature supports the need for programs better designed to meet the needs of adolescent substance treatment. There is little research, however, that addresses the identification of characteristics of those adolescents who do not complete treatment. Consequently, this study seeks to identify those characteristics of adolescents by segueing off of another study that proved successful in identifying characteristics among inpatient adult male substance abusers. This study looks at the archival data of 38 adolescents who attended outpatient substance abuse treatment at an experientially-based, substance abuse program designed for adolescents. Methodological processes included the use of demographic variables collected through …
A Study Of Classic Films And Their Portrayal Of The Mentally Ill., Allison Marie Plants
A Study Of Classic Films And Their Portrayal Of The Mentally Ill., Allison Marie Plants
Graduate Theses, Dissertations, and Problem Reports (ETD)
The media have an enormous influence on the way the public views mental illness. Their frequent and often flawed portrayals of the mentally ill cause negative feelings to develop. Media framing plays a powerful role in the portrayal of the mentally ill. The way the media portray the mentally ill directly affects how they are viewed in real life.
An Analysis Of West Virginia Lamb Marketing Alternatives., Doolarie Singh-Knights
An Analysis Of West Virginia Lamb Marketing Alternatives., Doolarie Singh-Knights
Graduate Theses, Dissertations, and Problem Reports (ETD)
This study provides a comprehensive overview of the current lamb production and marketing environments in WV in view of current and prospective industry changes. Production and marketing inefficiencies, declining demand together with stiff competition from foreign supplies are significant challenges facing the sheep industry. A survey was developed and administered to WV sheep producers to characterize their production and marketing environment, as well as their marketing needs and concerns. Lamb sale transactions from livestock auctions markets in WV were analyzed to determine price trends and price discovery models in the WV sheep industry. The SAS (Statistical Analysis System, 1985) Kruskal-Wallis …
Uric Acid As An Antioxidant And The Effect Of Changes In Plasma Uric Acid Concentrations On Broiler Susceptibility To Ascites, And, The Effect Of Diet And Strain On Growth, Feed Efficiency, And Amino Acid Retention In Hybrid Bluegill., Beth M. Stinefelt
Graduate Theses, Dissertations, and Problem Reports (ETD)
Study one investigated the ability of uric acid (UA) to scavenge reactive oxygen species (ROS) and the ability of UA to protect against ROS-mediated damage. Hydroxyl and superoxide radical ESR signals were reduced by addition of UA (P< 0.05). UA prevented lipid peroxidation in RAW 264.7 cells exposed to silica (P< 0.015). UA inhibited hydroxyl-mediated damage to λ Hind III DNA. The objective of study two was to determine the effect of changes in plasma UA (PUA) on growth and ascites development in broilers. Chicks were fed a grower diet supplemented with 0.5 moles inosine/kg feed to raise PUA, 15 mg allopurinol/kg body weight/day to lower PUA, or a control diet. Birds were housed in two environmental chambers; one had conditions to promote ascites while the second was held at standard conditions. Although dietary treatment had an effect on PUA, no effect of diet on performance or development of ascites was observed.
Ergot Alkaloids And Herbivory In Model Animals, And, Variation In An Ergot Alkaloid Biosynthesis Gene., Andrea B. Sedlock
Ergot Alkaloids And Herbivory In Model Animals, And, Variation In An Ergot Alkaloid Biosynthesis Gene., Andrea B. Sedlock
Graduate Theses, Dissertations, and Problem Reports (ETD)
Neotyphodium spp. are members of the fungal family Clavicipitaceae that grow endophytically within several important forage grasses, imparting benefits to the host grass. Several species produce toxic ergopeptines that are thought to adversely affect mammalian health. Inclusion of 1% agar in endophyte-infected seed diets was found to ameliorate some of the consequences of feeding endophyte-infected seeds to mice. Based upon feeding preferences of rabbits and mice, it seems that ergot alkaloids are not critical factors for deterring feeding on endophyte-infected plants by these animals, but the presence of the fungus appeared to deter rabbits. Intron-containing fragments of lysergyl peptide synthetase …
The Impact Of Caloric Preloading On Attempts At Food- And Eating-Related Thought Suppression In Restrained And Unrestrained Eaters., Cara Frances O'Connell
The Impact Of Caloric Preloading On Attempts At Food- And Eating-Related Thought Suppression In Restrained And Unrestrained Eaters., Cara Frances O'Connell
Graduate Theses, Dissertations, and Problem Reports (ETD)
The current study examined the relation between dietary restraint and caloric preload in thought suppression attempts. The impact of restraint status, suppression instructions, and a high calorie preload were examined among a sample of 64 college females classified as either restrained or unrestrained eaters. Participants engaged in a 60-minute laboratory activity; half of the participants were preloaded and all participants were randomly assigned to a food- and eatingrelated thought suppression condition or an expression control group. Difficulty of suppression and frequency of foods and eating-related thoughts were examined. Restrained participants instructed to suppress demonstrated significantly more food- and eating-related thoughts. …
Consumer Preferences For Genetically Modified Fish And Seafood: An Econometric Approach., Brian S. Bennett
Consumer Preferences For Genetically Modified Fish And Seafood: An Econometric Approach., Brian S. Bennett
Graduate Theses, Dissertations, and Problem Reports (ETD)
Genetic modification (GM) is a rapidly growing technology that can improve productivity and profitability for producers; however consumer acceptance of this technology is not fully understood, particularly as it relates to fish and seafood. The purpose of this study is to evaluate consumer perceptions of GM foods in general, and fresh fish and seafood in particular. A phone survey of a random sample of US households was conducted. A qualitative choice (Logit) model was used for estimation. LIMDEP was the computer package used to analyze the data. The marginal effects were also estimated. Results show that older, higher income, non …
Responsible Medical Narrative: Applying The Lessons Of Medical Journalism To Medical Narrative., Pamela Christine Kasey
Responsible Medical Narrative: Applying The Lessons Of Medical Journalism To Medical Narrative., Pamela Christine Kasey
Graduate Theses, Dissertations, and Problem Reports (ETD)
The media influence public health in two important ways: by affecting individual choices, and by affecting public policy. The media’s important roles with regard to public health have long raised concerns about responsible medical reporting. In recognition of the need for clarity in health communication to the public, various sets of tips and guidelines for reporters, editors, and others have been advanced. These guidelines apply primarily to news forms used for reporting scientific advances and conveying health recommendations: the traditional “inverted pyramid” story, the feature story, and service pieces. They are less applicable to narrative, a journalistic form that is …
The Effect Of Nutrition Education And "Hands On" Food Preparation Training On National Collegiate Athletic Association Division I Athletes' Nutrition Knowledge And Dietary Practices., Karin Lockhart Gould
The Effect Of Nutrition Education And "Hands On" Food Preparation Training On National Collegiate Athletic Association Division I Athletes' Nutrition Knowledge And Dietary Practices., Karin Lockhart Gould
Graduate Theses, Dissertations, and Problem Reports (ETD)
The purpose of the study was to determine whether collegiate athletes had a change in nutrition knowledge and, consequently, a positive change in diet intake, when given different types of nutrition education. Intervention was either participation in a newsletter group, or a cooking lesson group. Subjects were 24 athletes, male and female. The study design was a Pre-Test, Post-Test Questionnaire and Three-day Diet Record. Results were analyzed using ANOVA. Mean test score improved for both groups by 6.5% (p = 0.0004), there was no significant difference between groups. Every subject in the “Cooking class” improved on the test score from …
An Economic Analysis Of Pasture-Raised Beef Systems In Appalachia., Jason R. Evans
An Economic Analysis Of Pasture-Raised Beef Systems In Appalachia., Jason R. Evans
Graduate Theses, Dissertations, and Problem Reports (ETD)
Cow-calf operations are important enterprises for family farmers in Appalachia and provide significant opportunity for supplemental income. Alternatives to traditional production methods that not only offer higher income potential but also lower risk levels need to be addressed for the benefit of the region’s producers. This thesis presents an analysis of one such alternative, pasture-raised beef production. Stochastic budgeting was used to compare profit and risk levels experienced by numerous categories of grassfed and traditional producers. Results showed that risk in pasture-raised operations is primarily production-related while risk for traditional producers is price-related and is, in general, more severe than …
Physical Activity Perceptions In Adolescents: A Qualitative Analysis., Lindsey M. Parker
Physical Activity Perceptions In Adolescents: A Qualitative Analysis., Lindsey M. Parker
Graduate Theses, Dissertations, and Problem Reports (ETD)
The purpose of this research was to investigate adolescent perceptions of overweight and physical activity. Focus groups were used to collect information. Eight age- and gender- specific focus groups consisting of 48 participants (10 middle school males, 10 middle school females, 15 high school males, and 13 high school females). Perceptions of overweight, benefits, barriers and facilitators to being physically active were gathered among the groups and compared using age and gender. Males and females were found to differ in their overweight perceptions, perceived benefits of physical activity, their activity preferences, and barriers to physical activity. High school aged adolescents …
The Nutritional Management On Reproduction In Beef Replacement Heifers., James F. Kinsey
The Nutritional Management On Reproduction In Beef Replacement Heifers., James F. Kinsey
Graduate Theses, Dissertations, and Problem Reports (ETD)
The effects of dietary treatment, supplementation or forage only, on the induction of puberty, growth response, and fertility of 196 yearling beef heifers were investigated. Heifers were assigned to one of the two dietary treatments based on age and weight. Upon completion of the feeding trial (145d, year 1; 159d, year 2) all heifers were placed on one of three estrous synchronization protocols for timed artificial insemination and placed for one estrous cycle with a clean up bull for both years. Growth variables, (ADG and final weight) were enhanced by supplementation with soybean hull pellets. The effect of dietary treatment …
The Effect Of Dietary Lactose On The Performance Of Turkeys., Mabel Mbone Milimu
The Effect Of Dietary Lactose On The Performance Of Turkeys., Mabel Mbone Milimu
Graduate Theses, Dissertations, and Problem Reports (ETD)
An experiment was conducted involving 360 large white turkeys of mixed sex, raised in floor pens. The purpose of the experiment was to determine the effect of dietary lactose on the performance of turkeys and to determine the optimum amount of lactose inclusion in the diet. There were six diets and three replicates of each diet. The diets contained 0%, (commercial and control) 0.5%, 1%, 2% and 4% lactose and were randomly assigned to 18 pens with 20 birds per pen. Feed and water were offered ad libitum. There were no significant differences (p>0.05) among the diets in final …
The Mechanisms Of Ethanol-Induced Damage To The Developing Cerebellum: Effects On The Cerebellar Granule Cells., Zheng Li
Graduate Theses, Dissertations, and Problem Reports (ETD)
Alcohol exposure causes developmental abnormality known as Fetal Alcohol Syndrome (FAS), featured with central nervous system (CNS) dysfunction. The cerebellum is vulnerable to ethanol toxicity. Developmental exposure to ethanol depletes the number of cerebellar granule cells; however, the underlying mechanisms are unknown. A potential mechanism for ethanol-induced neuronal depletion is to reduce the pool of neuronal progenitors. The progression of the cell cycle is regulated by a family of protein kinases called cyclin-dependent kinases (CDKs). We hypothesize that ethanol interferes with the CDK system and disrupts the cell cycle kinetics in cerebellar granule progenitors (CGPs). Pregnant rats were fed ad …
The Effects Of Science Engineering Mathematics Aerospace Academy (Semaa) Participation On Engagement Rates Of Sixth- And Seventh-Grade Students In Regular Mathematics Classes., Donna R. Carr
Graduate Theses, Dissertations, and Problem Reports (ETD)
The purpose of this study was to investigate the impact of participation in a short-term, co-curricular, mathematics and science program (Science Engineering Mathematics Aerospace Academy, SEMAA) on the engagement rates of sixth and seventh grade students in public school mathematics classes. The outcome variable (engagement) was measured with the Student Record of Behavior at three time intervals. A 22.3 mixed ANOVA design was utilized to investigate three main effects (participation, grade level, and time) and their primary and secondary interactions. Results reflected no discernable impact of the SEMAA program on student engagement rates. Conclusions include alignment of ancillary programs and …
The Effects Of Resistance Training And Oral Creatine Supplementation On Muscle Fiber Morphology, Strength And Activities Of Daily Living In Patients With Charcot -Marie -Tooth Disease., Robert David Chetlin
The Effects Of Resistance Training And Oral Creatine Supplementation On Muscle Fiber Morphology, Strength And Activities Of Daily Living In Patients With Charcot -Marie -Tooth Disease., Robert David Chetlin
Graduate Theses, Dissertations, and Problem Reports (ETD)
Resistance exercise and creatine supplementation independently improve strength and function in patients with neuromuscular diseases, but the effectiveness of the two combined in patients with Charcot-Marie-Tooth (CMT) disease is unknown. Additionally, no study has examined gender differences in strength and activities of daily living (ADLs) in CMT patients before or after resistance training, nor has ADL performance been used for exercise prescription. Purposes. (1) To examine the effects of resistance training with and without creatine supplementation on muscle, strength and function in patients with CMT; (2) To compare effects of 12 weeks training on strength and ADLs in CMT men …
The Effect Of Emphysema On Adaptation Of Peripheral Skeletal Muscle To Different Loading Conditions In The Syrian Golden Hamster., Anne K. Swisher
The Effect Of Emphysema On Adaptation Of Peripheral Skeletal Muscle To Different Loading Conditions In The Syrian Golden Hamster., Anne K. Swisher
Graduate Theses, Dissertations, and Problem Reports (ETD)
Purpose. Severe emphysema affects peripheral skeletal muscle with only partial reversal with exercise training. The effects of mild emphysema on adaptation of peripheral skeletal muscle to different loading conditions are unknown. Methods. Male Syrian golden hamsters were instilled with saline (S, n = 6) or porcine elastase (E, n = 12) to induce mild emphysema prior to removal of the right Achilles tendon to induce overload (OV) of plantaris muscle and unloading (UL) of gastrocnemius. The left limb served as control (C). Six animals were sacrificed at 1, 3, and 5 months. Fiber type, citrate synthase activity (CS), and capillary …
Prepartum Milking Of Holstein Heifers: Prepartum Mastitis And Factors Affecting Heifers Milked Prepartum., Nancy Jean Kerr
Prepartum Milking Of Holstein Heifers: Prepartum Mastitis And Factors Affecting Heifers Milked Prepartum., Nancy Jean Kerr
Graduate Theses, Dissertations, and Problem Reports (ETD)
A field study was conducted on two commercial dairy production units to determine the effects of milking Holstein heifers prepartum on prepartum mastitis, reproduction, milk production, and overall health. Holstein heifers were assigned at least 30 days prior to the expected date of parturition to one of three treatment groups: Non-Prepartum Milked Control, Postpartum Milked (C; Farm 1, n = 31; Farm 2, n = 15), Prepartum Milked (P; Farm 1, n = 68; Farm 2, n = 16); and Prepartum Milked with Mastitis (M; Farm 1, n = 27; Farm 2, n = 4). Prepartum milking consisted of twice …
Beyond The Walls: A Research Study Of Eighth-Grade Students Mentored In A Hospital Setting., Aileen Grattan
Beyond The Walls: A Research Study Of Eighth-Grade Students Mentored In A Hospital Setting., Aileen Grattan
Graduate Theses, Dissertations, and Problem Reports (ETD)
This research study was designed to evaluate twelve eighth-grade students participating in the fourth year of a mentoring program to determine what effect the mentoring experience would have on the students' sense of a scientific community, their understanding of scientific knowledge and process skills and attitudes toward science. The mentoring program was developed through a partnership established between the researcher, an eighth-grade science teacher at a junior high school, and an administrator of a local hospital, to provide educational opportunities for students mentored by medical professionals. The research design included qualitative and quantitative methods of analysis. The qualitative instruments were …
The Role Of Retrochiasmatic Neurons In Seasonal Breeding In The Ewe., Steven L. Hardy
The Role Of Retrochiasmatic Neurons In Seasonal Breeding In The Ewe., Steven L. Hardy
Graduate Theses, Dissertations, and Problem Reports (ETD)
A seasonal change in GnRH secretion is well documented in sheep. An alteration in the estradiol (E2) negative feedback mechanism is thought to promote ovarian quiescence via GnRH inhibition during spring and summer months in response to changes in day length. It is evident that the hypothalamus becomes hypersensitive to E2 during this time, but the mechanism driving the shift is not completely understood. However, it is clear that A15 dopaminergic (DA) neurons in the retrochiasmatic area (RCh) play a key role in these seasonal changes. These neurons mediated E2 negative feedback in anestrus, but do not respond to E2 …
Effects Of Nitrogen Fertilizer And Red Clover (Trifolium Pratense L.) Component On Productivity Of Grass-Legume Mixed Swards, Chamil Salinda Kandapola
Effects Of Nitrogen Fertilizer And Red Clover (Trifolium Pratense L.) Component On Productivity Of Grass-Legume Mixed Swards, Chamil Salinda Kandapola
Graduate Theses, Dissertations, and Problem Reports (ETD)
The effects of two levels of red clover (low and high) and three levels of N fertilizer (0, 28, 56 N kg ha-1) on herbage accumulation and quality of grass-legume mixed swards were studied. Total herbage accumulation of the mixtures with high legume percentage was significantly higher than those with low legume percentage and this was most pronounced at second harvest. Swards high in legumes also had higher crude protein concentrations and lower weed percentages than those low in legumes. Although the effect of N on herbage accumulation was not significant, an increase was observed for crude protein concentration of …
Sport Fish Consumption Advisory For West Virginia, William Alvin Warnick
Sport Fish Consumption Advisory For West Virginia, William Alvin Warnick
Graduate Theses, Dissertations, and Problem Reports (ETD)
The risk based sport fish consumption advisory protocol, West Virginia Sport Fish Consumption Advisory Guide (the Guide), was drafted for the state. Fish were collected from ten West Virginia sites (5 previously identified as contaminated, 5 previously identified as uncontaminated). Fish samples were collected, processed and analyzed for total mercury concentration and Aroclors (PCBs). Recommended meal frequencies were calculated from contaminant levels and based on the Guide. Mean fillet sample contaminant levels were compared to composite sample levels and found to require the same level or in one case a more protective of consumption advisory. Ten composite samples had Aroclor …