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Washington University School of Medicine

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Procurement Of Human Tissues For Research Banking In The Surgical Pathology Laboratory: Prioritization Practices At Washington University Medical Center, Sandra A. Mcdonald, Rebecca D. Chernock, Tracey A. Leach, Ajaz A. Kahn, James H. Yip, Joan Rossi, John D. Pfeifer Jan 2011

Procurement Of Human Tissues For Research Banking In The Surgical Pathology Laboratory: Prioritization Practices At Washington University Medical Center, Sandra A. Mcdonald, Rebecca D. Chernock, Tracey A. Leach, Ajaz A. Kahn, James H. Yip, Joan Rossi, John D. Pfeifer

Open Access Publications

No abstract provided.


Do Shared Etiological Factors Contribute To The Relationship Between Sexual Orientation And Depression?, B. P. Zietsch, K. J H Verweij, A. C. Heath, P. A F Madden, N. G. Martin, E. C. Nelson, M. T. Lynskey Jan 2011

Do Shared Etiological Factors Contribute To The Relationship Between Sexual Orientation And Depression?, B. P. Zietsch, K. J H Verweij, A. C. Heath, P. A F Madden, N. G. Martin, E. C. Nelson, M. T. Lynskey

Open Access Publications

No abstract provided.


An Evolutionary Genomic Approach To Identify Genes Involved In Human Birth Timing, Jevon Plunkett, Scott Doniger, Guilherme Orabona, Thomas Morgan, Ritva Haataja, Mikko Hallman, Hilkka Puttonen, Ramkumar Menon, Edward Kuczynski, Errol Norwitz, Victoria Snegovskikh, Aarno Palotie, Leena Peltonen, Vineta Fellman, Emily A. Defranco, Bimal P. Chaudhari, Tracy L. Mcgregor, Jude J. Mcelroy, Matthew T. Oetjens, Kari Teramo, Ingrid Borecki, Justin Fay, Louis Muglia Jan 2011

An Evolutionary Genomic Approach To Identify Genes Involved In Human Birth Timing, Jevon Plunkett, Scott Doniger, Guilherme Orabona, Thomas Morgan, Ritva Haataja, Mikko Hallman, Hilkka Puttonen, Ramkumar Menon, Edward Kuczynski, Errol Norwitz, Victoria Snegovskikh, Aarno Palotie, Leena Peltonen, Vineta Fellman, Emily A. Defranco, Bimal P. Chaudhari, Tracy L. Mcgregor, Jude J. Mcelroy, Matthew T. Oetjens, Kari Teramo, Ingrid Borecki, Justin Fay, Louis Muglia

Open Access Publications

No abstract provided.


Dynamic Analysis Of Amyloid Β-Protein In Behaving Mice Reveals Opposing Changes In Isf Versus Parenchymal Aβ During Age-Related Plaque Formation, Soyon Hong, Omar Quintero-Monzon, Beth L. Ostaszewski, Daniel R. Podlisny, William T. Cavanaugh, Ting Yang, David M. Holtzman, John R. Cirrito, Dennis J. Selkoe Jan 2011

Dynamic Analysis Of Amyloid Β-Protein In Behaving Mice Reveals Opposing Changes In Isf Versus Parenchymal Aβ During Age-Related Plaque Formation, Soyon Hong, Omar Quintero-Monzon, Beth L. Ostaszewski, Daniel R. Podlisny, William T. Cavanaugh, Ting Yang, David M. Holtzman, John R. Cirrito, Dennis J. Selkoe

Open Access Publications

No abstract provided.


Micrornas Modulate Schwann Cell Response To Nerve Injury By Reinforcing Transcriptional Silencing Of Dedifferentiation-Related Genes, Andreu Viader, Li-Wei Chang, Timothy Fahrner, Rakesh Nagarajan, Jeffrey Milbrandt Jan 2011

Micrornas Modulate Schwann Cell Response To Nerve Injury By Reinforcing Transcriptional Silencing Of Dedifferentiation-Related Genes, Andreu Viader, Li-Wei Chang, Timothy Fahrner, Rakesh Nagarajan, Jeffrey Milbrandt

Open Access Publications

No abstract provided.


A Clustering Analysis Of Lipoprotein Diameters In The Metabolic Syndrome, Alexis C. Frazier-Wood, Stephen Glasser, W Timothy Garvey, Edmond K. Kabagambe, Ingrid B. Borecki, Hemant K. Tiwari, Michael Y. Tsai, Paul N. Hopkins, Jose M. Ordovas, Donna K. Arnett Jan 2011

A Clustering Analysis Of Lipoprotein Diameters In The Metabolic Syndrome, Alexis C. Frazier-Wood, Stephen Glasser, W Timothy Garvey, Edmond K. Kabagambe, Ingrid B. Borecki, Hemant K. Tiwari, Michael Y. Tsai, Paul N. Hopkins, Jose M. Ordovas, Donna K. Arnett

Open Access Publications

No abstract provided.


Resorufin Analogs Preferentially Bind Cerebrovascular Amyloid: Potential Use As Imaging Ligands For Cerebral Amyloid Angiopathy, Byung Hee Han, Meng-Liang Zhou, Ananth K. Vellimana, Eric Milner, David H. Kim, Jacob K. Greenberg, Wenhua Chu, Robert H. Mach, Gregory J. Zipfel Jan 2011

Resorufin Analogs Preferentially Bind Cerebrovascular Amyloid: Potential Use As Imaging Ligands For Cerebral Amyloid Angiopathy, Byung Hee Han, Meng-Liang Zhou, Ananth K. Vellimana, Eric Milner, David H. Kim, Jacob K. Greenberg, Wenhua Chu, Robert H. Mach, Gregory J. Zipfel

Open Access Publications

No abstract provided.


Golgi Cells Operate As State-Specific Temporal Filters At The Input Stage Of The Cerebellar Cortex, Shane A. Heine, Stephen M. Highstein, Pablo M. Blazquez Dec 2010

Golgi Cells Operate As State-Specific Temporal Filters At The Input Stage Of The Cerebellar Cortex, Shane A. Heine, Stephen M. Highstein, Pablo M. Blazquez

Open Access Publications

Cerebellar processing of incoming information begins at the synapse between mossy fibers and granule cells, a synapse that is strongly controlled through Golgi cell inhibition. Thus, Golgi cells are uniquely positioned to control the flow of information into the cerebellar cortex and understanding their responses during behavior is essential to understanding cerebellar function. Here we show, for the first time, that Golgi cells express a unique oculomotor-related signal that can be used to provide state- and time-specific filtering of granule cell activity. We used newly established criteria to identify the unique electrophysiological signature of Golgi cells and recorded these neurons …


Membrane Anchoring Subunits Specify Selective Regulation Of Rgs9·Gbeta5 Gap Complex In Photoreceptor Neurons, Yan Cao, Alexander V. Kolesnikov, Ikuo Masuho, Vladimir J. Kefalov, Kirill A. Martemyanov Oct 2010

Membrane Anchoring Subunits Specify Selective Regulation Of Rgs9·Gbeta5 Gap Complex In Photoreceptor Neurons, Yan Cao, Alexander V. Kolesnikov, Ikuo Masuho, Vladimir J. Kefalov, Kirill A. Martemyanov

Open Access Publications

The RGS9·Gβ5 complex is the key regulator of neuronal G-protein signaling and shows remarkable selectivity of subunit composition. In retinal photoreceptors, RGS9·Gβ5 is bound to the membrane anchor R9AP and the complex regulates visual signaling. In the basal ganglia neurons, RGS9·Gβ5 is instead associated with a homologous protein, R7BP, and regulates reward circuit. Switching this selective subunit composition of the complex in rod photoreceptors allowed us to study the molecular underpinning of signaling specificity in diverse G-protein pathways. We have found that both membrane anchoring subunits play a conserved role in regulating protein levels of RGS9·Gβ5 and enhancing the ability …


Protein Turnover Of The Wallenda/Dlk Kinase Regulates A Retrograde Response To Axonal Injury, Xin Xiong, Xin Wang, Ronny Ewanek, Pavan Bhat, Aaron Diantonio, Catherine A. Collins Oct 2010

Protein Turnover Of The Wallenda/Dlk Kinase Regulates A Retrograde Response To Axonal Injury, Xin Xiong, Xin Wang, Ronny Ewanek, Pavan Bhat, Aaron Diantonio, Catherine A. Collins

Open Access Publications

No abstract provided.


What's New In Spine Surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, Jeffrey C. Wang Aug 2010

What's New In Spine Surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, Jeffrey C. Wang

Open Access Publications

No abstract provided.


Comparison Of Costs Of Surgical Site Infection And Endometritis After Cesarean Delivery Using Claims And Medical Record Data, Margaret A. Olsen, Anne M. Butler, Denise M. Willers, Gilad A. Gross, Victoria J. Fraser Aug 2010

Comparison Of Costs Of Surgical Site Infection And Endometritis After Cesarean Delivery Using Claims And Medical Record Data, Margaret A. Olsen, Anne M. Butler, Denise M. Willers, Gilad A. Gross, Victoria J. Fraser

Infectious Diseases Faculty Publications

No abstract provided.


Bjc Today Jul 2010

Bjc Today

BJC Today

No abstract provided.


Bjc Today Jul 2010

Bjc Today

BJC Today

No abstract provided.


Dynamic Contact Mechanics Of The Medial Meniscus As A Function Of Radial Tear, Repair, And Partial Meniscectomy, Asheesh Bedi, Natalie H. Kelly, Michael Baad, Alice J.S. Fox, Robert H. Brophy, Russell F. Warren, Suzanne A. Maher Jun 2010

Dynamic Contact Mechanics Of The Medial Meniscus As A Function Of Radial Tear, Repair, And Partial Meniscectomy, Asheesh Bedi, Natalie H. Kelly, Michael Baad, Alice J.S. Fox, Robert H. Brophy, Russell F. Warren, Suzanne A. Maher

Open Access Publications

No abstract provided.


Bjc Today May 2010

Bjc Today

BJC Today

No abstract provided.


Molecular Dissection Of I(A) In Cortical Pyramidal Neurons Reveals Three Distinct Components Encoded By Kv4.2, Kv4.3, And Kv1.4 Alpha-Subunits, Aaron J. Norris, Jeanne M. Nerbonne Apr 2010

Molecular Dissection Of I(A) In Cortical Pyramidal Neurons Reveals Three Distinct Components Encoded By Kv4.2, Kv4.3, And Kv1.4 Alpha-Subunits, Aaron J. Norris, Jeanne M. Nerbonne

Open Access Publications

The rapidly activating and inactivating voltage-gated K(+) (Kv) current, I(A), is broadly expressed in neurons and is a key regulator of action potential repolarization, repetitive firing, backpropagation (into dendrites) of action potentials, and responses to synaptic inputs. Interestingly, results from previous studies on a number of neuronal cell types, including hippocampal, cortical, and spinal neurons, suggest that macroscopic I(A) is composed of multiple components and that each component is likely encoded by distinct Kv channel alpha-subunits. The goals of the experiments presented here were to test this hypothesis and to determine the molecular identities of the Kv channel alpha-subunits that …


Focal Spot, Spring/Summer 2010 Apr 2010

Focal Spot, Spring/Summer 2010

Focal Spot All Issues

No abstract provided.


Relationship Of Tear Size And Location To Fatty Degeneration Of The Rotator Cuff, H. Mike Kim, Nirvikar Dahiya, Sharlene A. Teefey, Jay D. Keener, Leesa M. Galatz, Ken Yamaguchi Apr 2010

Relationship Of Tear Size And Location To Fatty Degeneration Of The Rotator Cuff, H. Mike Kim, Nirvikar Dahiya, Sharlene A. Teefey, Jay D. Keener, Leesa M. Galatz, Ken Yamaguchi

Open Access Publications

No abstract provided.


Attributable Costs Of Surgical Site Infection And Endometritis After Low Transverse Cesarean Delivery, Margaret A. Olsen, Anne M. Butler, Denise M. Willers, Gilad A. Gross, Barton H. Hamilton, Victoria J. Fraser Mar 2010

Attributable Costs Of Surgical Site Infection And Endometritis After Low Transverse Cesarean Delivery, Margaret A. Olsen, Anne M. Butler, Denise M. Willers, Gilad A. Gross, Barton H. Hamilton, Victoria J. Fraser

Infectious Diseases Faculty Publications

No abstract provided.


Risk Factors For Endometritis After Low Transverse Cesarean Delivery, Margaret A. Olsen, Anne M. Butler, Denise M. Willers, Gilad A. Gross, Preetishma Devkota, Victoria J. Fraser Mar 2010

Risk Factors For Endometritis After Low Transverse Cesarean Delivery, Margaret A. Olsen, Anne M. Butler, Denise M. Willers, Gilad A. Gross, Preetishma Devkota, Victoria J. Fraser

Infectious Diseases Faculty Publications

No abstract provided.


Pacs Bulletin 2010-2011, Program In Audiology And Communication Sciences Jan 2010

Pacs Bulletin 2010-2011, Program In Audiology And Communication Sciences

PACS News

No abstract provided.


Institute Of Clinical And Translational Sciences News, Vol. 2, Issue 9 Jan 2010

Institute Of Clinical And Translational Sciences News, Vol. 2, Issue 9

ICTS Newsletters

No abstract provided.


A Genome-Wide Association Study Of Self-Rated Health, Miriam A. Mosing, Karin J.H. Verweij, Sarah E. Medland, Jodie Painter, Scott D. Gordon, Andrew C. Heath, Pamela A. Madden, Grant W. Montgomery, Nicholas G. Martin Jan 2010

A Genome-Wide Association Study Of Self-Rated Health, Miriam A. Mosing, Karin J.H. Verweij, Sarah E. Medland, Jodie Painter, Scott D. Gordon, Andrew C. Heath, Pamela A. Madden, Grant W. Montgomery, Nicholas G. Martin

Open Access Publications

No abstract provided.


Gender Specific Effects Of Perinatal Influences On The Risk For Alcoholism In A 45-Year Danish Birth Cohort, Anna Manzardo, Wendy Madarasz, Elizabeth C. Penick, Joachim Knop, Erik Lykke Mortensen, Holger J. Sorenson, Ulrik Becker, Elizabeth J. Nickel, William F. Gabrielli Jr. Jan 2010

Gender Specific Effects Of Perinatal Influences On The Risk For Alcoholism In A 45-Year Danish Birth Cohort, Anna Manzardo, Wendy Madarasz, Elizabeth C. Penick, Joachim Knop, Erik Lykke Mortensen, Holger J. Sorenson, Ulrik Becker, Elizabeth J. Nickel, William F. Gabrielli Jr.

Posters

No abstract provided.


Histological And Functional Aspects Of Alpha-Synuclein In Neurodegeneration, Lauren Noelle Lawler Jan 2010

Histological And Functional Aspects Of Alpha-Synuclein In Neurodegeneration, Lauren Noelle Lawler

Independent Studies and Capstones

Alpha-synuclein has been implicated in the cellular mechanisms that control auditory sensitivity. In other systems it can also confer protection against cellular injury. Auditory brainstem response thresholds and immunohistochemistry were used to assess the ability of alpha-synuclein to protect against oxidative damage to the cochlea.


Phospholipase C Gamma 2 Is Critical For Development Of A Murine Model Of Inflammatory Arthritis By Affecting Actin Dynamics In Dendritic Cells, Viviana Cremasco, Elisa Benasciutti, Marina Cella, Marina Kisseleva, Monica Croke, Roberta Faccio Jan 2010

Phospholipase C Gamma 2 Is Critical For Development Of A Murine Model Of Inflammatory Arthritis By Affecting Actin Dynamics In Dendritic Cells, Viviana Cremasco, Elisa Benasciutti, Marina Cella, Marina Kisseleva, Monica Croke, Roberta Faccio

ICTS Faculty Publications

No abstract provided.


Sexually Transmitted Infections And Risk Of Prostate Cancer: Review Of Historical And Emerging Hypotheses., Siobhan Sutcliffe Jan 2010

Sexually Transmitted Infections And Risk Of Prostate Cancer: Review Of Historical And Emerging Hypotheses., Siobhan Sutcliffe

Epidemiology Faculty Publications

No abstract provided.


Institute Of Clinical And Translational Sciences News, Vol. 3, Issue 3 Jan 2010

Institute Of Clinical And Translational Sciences News, Vol. 3, Issue 3

ICTS Newsletters

No abstract provided.


Period2 Gene Deletion Abolishes Αmelanocyte Stimulating Hormone Response To Ethanol, M. A. Agapito, J. C. Barreira, D. K. Sarkar Jan 2010

Period2 Gene Deletion Abolishes Αmelanocyte Stimulating Hormone Response To Ethanol, M. A. Agapito, J. C. Barreira, D. K. Sarkar

Posters

No abstract provided.