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Washington University School of Medicine

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The Relation Between Speech Recognition In Noise And The Speech-Evoked Brainstem Response In Normal-Hearing And Hearing-Impaired Individuals, Sheli Lipson Jan 2012

The Relation Between Speech Recognition In Noise And The Speech-Evoked Brainstem Response In Normal-Hearing And Hearing-Impaired Individuals, Sheli Lipson

Independent Studies and Capstones

Little is known about the way speech in noise is processed along the auditory pathway. The purpose of this study was to evaluate the relation between listening in noise using the R-Space system and the neurophysiologic response of the speech-evoked auditory brainstem when recorded in quiet and noise in adult participants with mild to moderate hearing loss and normal hearing.


Educating And Motivating Adolescents Who Are Deaf Or Hard Of Hearing With Drug And Alcohol Addiction: Components Of A Curriculum That Links Adolescents To Appropriate Treatment, Lindsey K. Legendre Jan 2012

Educating And Motivating Adolescents Who Are Deaf Or Hard Of Hearing With Drug And Alcohol Addiction: Components Of A Curriculum That Links Adolescents To Appropriate Treatment, Lindsey K. Legendre

Independent Studies and Capstones

This paper highlights the components necessary for a drug and alcohol addiction curricula to educate, motivate, and link adolescents who are deaf or hard of hearing using oral communication to appropriate treatment.


Acceptable Noise Levels For Neonates In The Neonatal Intensive Care Unit, Allysa Jennie Knutson Jan 2012

Acceptable Noise Levels For Neonates In The Neonatal Intensive Care Unit, Allysa Jennie Knutson

Independent Studies and Capstones

The study was a sound survey of naturally occurring noise in a metropolitan hospital NICU. The collected sound level samples were then compared to the noise standard recommended by the American Academy of Pediatrics. It was concluded that sound levels in the NICU exceed the standard and the standard does not have a proper foundation.


Cisplatin Ototoxicity And Hair Cell Regeneration In The Zebrafish Lateral Line, Alisa A. Genualdi Jan 2012

Cisplatin Ototoxicity And Hair Cell Regeneration In The Zebrafish Lateral Line, Alisa A. Genualdi

Independent Studies and Capstones

Hair cell death and regeneration on the zebrafish posterior lateral line was investigated after cisplatin administration. Hair cell regeneration was first observed by 24 hours of recovery and was further analyzed after specific recovery intervals. Disruption of the notch signaling pathways by the y-secretase inhibitor DAPT resulted in an increase in hair cells at three days of recovery.


Accuracy Of Fall Prediction In Parkinson Disease: Six-Month And 12-Month Prospective Analyses, Ryan P. Duncan, Abigail L. Leddy, James T. Cavanaugh, Leland E. Dibble, Terry D. Ellis, Matthew P. Ford, K. B. Foreman, Gammon M. Earhart Jan 2012

Accuracy Of Fall Prediction In Parkinson Disease: Six-Month And 12-Month Prospective Analyses, Ryan P. Duncan, Abigail L. Leddy, James T. Cavanaugh, Leland E. Dibble, Terry D. Ellis, Matthew P. Ford, K. B. Foreman, Gammon M. Earhart

Open Access Publications

No abstract provided.


Co-Survival Of The Fittest Few: Mosaic Amplification Of Receptor Tyrosine Kinases In Glioblastoma, Chen Feng, Li Ding Jan 2012

Co-Survival Of The Fittest Few: Mosaic Amplification Of Receptor Tyrosine Kinases In Glioblastoma, Chen Feng, Li Ding

Open Access Publications

No abstract provided.


Wlds But Not Nmnat1 Protects Dopaminergic Neurites From Mpp+ Neurotoxicity, Jo Ann V. Antenor-Dorsey, Karen O'Malley Jan 2012

Wlds But Not Nmnat1 Protects Dopaminergic Neurites From Mpp+ Neurotoxicity, Jo Ann V. Antenor-Dorsey, Karen O'Malley

Open Access Publications

No abstract provided.


The Circadian Neuropeptide Pdf Signals Preferentially Through A Specific Adenylate Cyclase Isoform Ac3 In M Pacemakers Of Drosophila, Laura B. Duvall, Paul H. Taghert Jan 2012

The Circadian Neuropeptide Pdf Signals Preferentially Through A Specific Adenylate Cyclase Isoform Ac3 In M Pacemakers Of Drosophila, Laura B. Duvall, Paul H. Taghert

Open Access Publications

No abstract provided.


Proteasome-Dependent Disruption Of The E3 Ubiquitin Ligase Anaphase-Promoting Complex By Hcmv Protein Pul21a, Anthony R. Fehr, Nathaniel C. Gualberto, John Paul Savaryn, Scott S. Terhune, Dong Yu Jan 2012

Proteasome-Dependent Disruption Of The E3 Ubiquitin Ligase Anaphase-Promoting Complex By Hcmv Protein Pul21a, Anthony R. Fehr, Nathaniel C. Gualberto, John Paul Savaryn, Scott S. Terhune, Dong Yu

Open Access Publications

No abstract provided.


Chemokine Gpcr Signaling Inhibits Beta-Catenin During Zebrafish Axis Formation, Shu-Yu Wu, Jimann Shin, Diane S. Sepich, Lilianna Solnica-Krezel Jan 2012

Chemokine Gpcr Signaling Inhibits Beta-Catenin During Zebrafish Axis Formation, Shu-Yu Wu, Jimann Shin, Diane S. Sepich, Lilianna Solnica-Krezel

Open Access Publications

No abstract provided.


Fatty Acid Oxidation Is Essential For Egg Production By The Parasitic Flatworm Schistosoma Mansoni, Stanley Ching-Cheng Huang, Tori C. Freitas, Eyal Amiel, Bart Everts, Erika L. Pearce, James B. Lok, Edward J. Pearce Jan 2012

Fatty Acid Oxidation Is Essential For Egg Production By The Parasitic Flatworm Schistosoma Mansoni, Stanley Ching-Cheng Huang, Tori C. Freitas, Eyal Amiel, Bart Everts, Erika L. Pearce, James B. Lok, Edward J. Pearce

Open Access Publications

No abstract provided.


Chfr Is Important For The First Wave Of Ubiquitination At Dna Damage Sites, Chao Liu, Jiaxue Wu, Sharad C. Paudyal, Zhongsheng You, Xiaochun Yu Jan 2012

Chfr Is Important For The First Wave Of Ubiquitination At Dna Damage Sites, Chao Liu, Jiaxue Wu, Sharad C. Paudyal, Zhongsheng You, Xiaochun Yu

Open Access Publications

No abstract provided.


Whole Genome Sequence Of Treponema Pallidum Ssp. Pallidum, Strain Mexico A, Suggests Recombination Between Yaws And Syphilis Strains, Helena Petrosova, Maria Zobanikova, Darina Cejkova, Lenka Mikalova, Petra Pospisilova, Michal Strouhal, Lei Chen, Xiang Qin, Donna M. Muzny, George M. Weinstock, David Smajs Jan 2012

Whole Genome Sequence Of Treponema Pallidum Ssp. Pallidum, Strain Mexico A, Suggests Recombination Between Yaws And Syphilis Strains, Helena Petrosova, Maria Zobanikova, Darina Cejkova, Lenka Mikalova, Petra Pospisilova, Michal Strouhal, Lei Chen, Xiang Qin, Donna M. Muzny, George M. Weinstock, David Smajs

Open Access Publications

No abstract provided.


Interferon-Induced Ifit2/Isg54 Protects Mice From Lethal Vsv Neuropathogenesis, Volker Fensterl, Jaime L. Wetzel, Srividya Ramachandran, Tomoaki Ogino, Stephen A. Stohlman, Cornelia C. Bergmann, Michael S. Diamond, Herbert W. Virgin, Ganes C. Sen Jan 2012

Interferon-Induced Ifit2/Isg54 Protects Mice From Lethal Vsv Neuropathogenesis, Volker Fensterl, Jaime L. Wetzel, Srividya Ramachandran, Tomoaki Ogino, Stephen A. Stohlman, Cornelia C. Bergmann, Michael S. Diamond, Herbert W. Virgin, Ganes C. Sen

Open Access Publications

No abstract provided.


Metabolic Reconstruction For Metagenomic Data And Its Application To The Human Microbiome, Sahar Abubucker, Nicola Segata, Johannes Goll, Alyxandria M. Schubert, Jacques Izard, Brandi L. Cantarel, Beltran Rodriguez-Mueller, Jeremy Zucker, Mathangi Thiagarajan, Bernard Henrissat, Owen White, Scott T. Kelly, Barbara Methe, Patrick D. Schloss, Dirk Gevers, Makedonka Mitreva, Curtis Huttenhower Jan 2012

Metabolic Reconstruction For Metagenomic Data And Its Application To The Human Microbiome, Sahar Abubucker, Nicola Segata, Johannes Goll, Alyxandria M. Schubert, Jacques Izard, Brandi L. Cantarel, Beltran Rodriguez-Mueller, Jeremy Zucker, Mathangi Thiagarajan, Bernard Henrissat, Owen White, Scott T. Kelly, Barbara Methe, Patrick D. Schloss, Dirk Gevers, Makedonka Mitreva, Curtis Huttenhower

Open Access Publications

No abstract provided.


Novel Modeling Of Combinatorial Mirna Targeting Identifies Snp With Potential Role In Bone Density, Claudia Coronnello, Ryan Hartmaier, Arshi Arora, Luai Huleihel, Kusum V. Padit, Abha S. Bais, Michael Butterworth, Naftali Kaminski, Gary D. Stormo, Steffi Oesterreich, Panayiotis V. Benos Jan 2012

Novel Modeling Of Combinatorial Mirna Targeting Identifies Snp With Potential Role In Bone Density, Claudia Coronnello, Ryan Hartmaier, Arshi Arora, Luai Huleihel, Kusum V. Padit, Abha S. Bais, Michael Butterworth, Naftali Kaminski, Gary D. Stormo, Steffi Oesterreich, Panayiotis V. Benos

Open Access Publications

No abstract provided.


A Model Of Spatially Restricted Transcription In Opposing Gradients Of Activators And Repressors, Michael A. White, Davis S. Parker, Scott Barolo, Barak A. Cohen Jan 2012

A Model Of Spatially Restricted Transcription In Opposing Gradients Of Activators And Repressors, Michael A. White, Davis S. Parker, Scott Barolo, Barak A. Cohen

Open Access Publications

No abstract provided.


Actin Cap Associated Focal Adhesions And Their Distinct Role In Cellular Mechanosensing, Dong-Hwee Kim, Shyam B. Khatau, Yunfeng Feng, Sam Walcott, Sean X. Sun, Gregory D. Longmore, Denis Wirtz Jan 2012

Actin Cap Associated Focal Adhesions And Their Distinct Role In Cellular Mechanosensing, Dong-Hwee Kim, Shyam B. Khatau, Yunfeng Feng, Sam Walcott, Sean X. Sun, Gregory D. Longmore, Denis Wirtz

Open Access Publications

No abstract provided.


Multi-Locus Genome-Wide Association Analysis Supports The Role Of Glutamatergic Synaptic Transmission In The Etiology Of Major Depressive Disorder, M. L. Pergadia, Et Al Jan 2012

Multi-Locus Genome-Wide Association Analysis Supports The Role Of Glutamatergic Synaptic Transmission In The Etiology Of Major Depressive Disorder, M. L. Pergadia, Et Al

Open Access Publications

No abstract provided.


Dj-1 Isoforms In Whole Blood As Potential Biomarkers Of Parkinson Disease, Xiangmin Lin, Travis J. Cook, Cyrus P. Zabetian, James B. Leverenz, Elaine R. Peskind, Shu-Ching Hu, Kevin C. Cain, Catherine Pan, John Scott Edgar, David R. Goodlett, Brad A. Racette, Harvey Checkoway, Thomas J. Montine, Min Shi, Jing Zhang Jan 2012

Dj-1 Isoforms In Whole Blood As Potential Biomarkers Of Parkinson Disease, Xiangmin Lin, Travis J. Cook, Cyrus P. Zabetian, James B. Leverenz, Elaine R. Peskind, Shu-Ching Hu, Kevin C. Cain, Catherine Pan, John Scott Edgar, David R. Goodlett, Brad A. Racette, Harvey Checkoway, Thomas J. Montine, Min Shi, Jing Zhang

Open Access Publications

No abstract provided.


Unraveling The Genetic Etiology Of Adult Antisocial Behavior: A Genome-Wide Association Study, Jorim J. Tielbeek, Sarah E. Medland, Beben Benyamin, Enda M. Byrne, Andrew C. Heath, Pamela A. F. Madden, Nicholas G. Martin, Naomi R. Wray, Karin J. H. Verweij Jan 2012

Unraveling The Genetic Etiology Of Adult Antisocial Behavior: A Genome-Wide Association Study, Jorim J. Tielbeek, Sarah E. Medland, Beben Benyamin, Enda M. Byrne, Andrew C. Heath, Pamela A. F. Madden, Nicholas G. Martin, Naomi R. Wray, Karin J. H. Verweij

Open Access Publications

No abstract provided.


Transcriptomic And Proteomic Analyses Of A Wolbachia- Free Filarial Parasite Provide Evidence Of Trans-Kingdom Horizontal Gene Transfer, Samantha N. Mcnulty, Sahar Abubucker, Gabriel M. Simon, Makedonka Mitreva, Nathan P. Mcnulty, Kerstin Fischer, Kurt C. Curtis, Norbert W. Brattig, Gary J. Weil, Peter U. Fischer Jan 2012

Transcriptomic And Proteomic Analyses Of A Wolbachia- Free Filarial Parasite Provide Evidence Of Trans-Kingdom Horizontal Gene Transfer, Samantha N. Mcnulty, Sahar Abubucker, Gabriel M. Simon, Makedonka Mitreva, Nathan P. Mcnulty, Kerstin Fischer, Kurt C. Curtis, Norbert W. Brattig, Gary J. Weil, Peter U. Fischer

Open Access Publications

No abstract provided.


Absence Of Ca2+-Stimulated Adenylyl Cyclases Leads To Reduced Synaptic Plasticity And Impaired Experience-Dependent Fear Memory, L. Wieczorek, D. Majumdar, T. A. Wills, L. Hu, D. G. Winder, D. J. Webb, L. J. Muglia Jan 2012

Absence Of Ca2+-Stimulated Adenylyl Cyclases Leads To Reduced Synaptic Plasticity And Impaired Experience-Dependent Fear Memory, L. Wieczorek, D. Majumdar, T. A. Wills, L. Hu, D. G. Winder, D. J. Webb, L. J. Muglia

Open Access Publications

No abstract provided.


A Genome-Wide Meta-Analysis Of Association Studies Of Cloninger's Temperament Scales, A. C. Heath, P. A. F. Madden, Et Al Jan 2012

A Genome-Wide Meta-Analysis Of Association Studies Of Cloninger's Temperament Scales, A. C. Heath, P. A. F. Madden, Et Al

Open Access Publications

No abstract provided.


Genome-Wide Meta-Analyses Of Smoking Behaviors In African Americans, Y. J. Sung, D. C. Rao, Et Al Jan 2012

Genome-Wide Meta-Analyses Of Smoking Behaviors In African Americans, Y. J. Sung, D. C. Rao, Et Al

Open Access Publications

No abstract provided.


Deciphering A Global Network Of Functionally Associated Post-Translational Modifications, Pablo Minguez, Luca Parca, Francesca Diella, Daniel R. Mende, Runjun Kumar, Manuela Helmer-Citterich, Anne-Claude Gavin, Vera Van Noort, Peer Bork Jan 2012

Deciphering A Global Network Of Functionally Associated Post-Translational Modifications, Pablo Minguez, Luca Parca, Francesca Diella, Daniel R. Mende, Runjun Kumar, Manuela Helmer-Citterich, Anne-Claude Gavin, Vera Van Noort, Peer Bork

Open Access Publications

No abstract provided.


The Distinct Roles Of The Nucleus And Nucleus-Cytoskeleton Connections In Three-Dimensional Cell Migration, Shyam B. Khatau, Ryan J. Bloom, Saumendra Bajpai, David Razafsky, Shu Zhang, Anjil Giri, Pei-Hsun Wu, Jorge Marchand, Alfredo Celedon, Christopher M. Hale, Sean X. Sun, Didier Hodzic, Denis Wirtz Jan 2012

The Distinct Roles Of The Nucleus And Nucleus-Cytoskeleton Connections In Three-Dimensional Cell Migration, Shyam B. Khatau, Ryan J. Bloom, Saumendra Bajpai, David Razafsky, Shu Zhang, Anjil Giri, Pei-Hsun Wu, Jorge Marchand, Alfredo Celedon, Christopher M. Hale, Sean X. Sun, Didier Hodzic, Denis Wirtz

Open Access Publications

No abstract provided.


Ubiquitination And Degradation Of The Hominoid- Specific Oncoprotein Tbc1d3 Is Mediated By Cul7 E3 Ligase, Chen Kong, Dmitri Samovski, Priya Srikanth, Marisa J. Wainszelbaum, Audra J. Charron, Jialiu Liu, Jeffrey J. Lange, Pin-I Chen, Zhen-Qiang Pan, Xiong Su, Philip D. Stahl Jan 2012

Ubiquitination And Degradation Of The Hominoid- Specific Oncoprotein Tbc1d3 Is Mediated By Cul7 E3 Ligase, Chen Kong, Dmitri Samovski, Priya Srikanth, Marisa J. Wainszelbaum, Audra J. Charron, Jialiu Liu, Jeffrey J. Lange, Pin-I Chen, Zhen-Qiang Pan, Xiong Su, Philip D. Stahl

Open Access Publications

No abstract provided.


Mouse Transgenesis In A Single Locus With Independent Regulation For Multiple Fluorophores, Joseph D. Dougherty, Juliet Zhang, Huifen Feng, Shiaoching Gong, Nathaniel Heintz Jan 2012

Mouse Transgenesis In A Single Locus With Independent Regulation For Multiple Fluorophores, Joseph D. Dougherty, Juliet Zhang, Huifen Feng, Shiaoching Gong, Nathaniel Heintz

Open Access Publications

No abstract provided.


A Bioinformatics Filtering Strategy For Identifying Radiation Response Biomarker Candidates, Jung Hun Oh, Harry P. Wong, Xiaowei Wang, Joseph O. Deasy Jan 2012

A Bioinformatics Filtering Strategy For Identifying Radiation Response Biomarker Candidates, Jung Hun Oh, Harry P. Wong, Xiaowei Wang, Joseph O. Deasy

Open Access Publications

No abstract provided.