Digital Commons Network^™

What's New In Orthopaedic Trauma, William M. Ricci, Andre Spiguel, Christopher Mcandrew, Michael Gardner

Open Access Publications

No abstract provided.

Counting Unstained, Confluent Cells By Modified Bright-Field Microscopy, L. Louis Drey, Michael Graber, Jan Bieschke

Open Access Publications

We present a very simple procedure yielding high-contrast images of adherent, confluent cells such as human neuroblastoma (SH-EP) cells by ordinary bright-field microscopy. Cells are illuminated through a color filter and a pinhole aperture placed between the condenser and the cell culture surface. Refraction by each cell body generates a sharp, bright spot when the image is defocused. The technique allows robust, automatic cell counting from a single bright-field image in a wide range of focal positions using free, readily available image-analysis tools. Contrast may be enhanced by swelling cell bodies with a brief incubation in PBS. The procedure was …

What's New In Spine Surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, Jeffrey C. Wang

Open Access Publications

No abstract provided.

Camera-Port Site Metastasis Of A Renal-Cell Carcinoma After Robot-Assisted Partial Nephrectomy, Joseph B. Song, Youssef S. Tanagho, Eric H. Kim, Phillip H. Abbosh, Phillip H. Abbosh, Goutham Vemana, R. Sherburne Figenshau

Open Access Publications

No abstract provided.

Global Analysis Of Drosophila Cys2-His2 Zinc Finger Proteins Reveals A Multitude Of Novel Recognition Motifs And Binding Determinants, Ryan G. Christensen, Gary D. Stormo, Et Al

Open Access Publications

No abstract provided.

Obesity Is Associated With Poor Surgical Outcome In Crohn's Disease, Talha Malik, Ashish Manne, Robert Oster, Austin Eckhoff, Seidu Inusah, Alexandra M Gutierrez

Open Access Publications

BACKGROUND: Published data suggest a link between obesity and adverse outcomes in Crohn's disease (CD). We aimed to test the hypothesis that obese CD patients would be more likely than non-obese CD patients to have poor surgical outcome when undergoing surgery for a complication of CD.

METHODS: We designed a retrospective cohort study to test our hypothesis. The population comprised of adult CD patients who underwent CD related surgery at a tertiary referral center. The exposed and unexposed cohorts were represented by patients who were obese vs. non-obese at the pre-op visit respectively. Outcome was represented by successful vs. unsuccessful …

Bjc Today

BJC Today

No abstract provided.

Protective Effect Of Surfactant Protein D In Pulmonary Vaccinia Virus Infection: Implication Of A27 Viral Protein, Julien Perino, Nicole M. Thielens, Erika Crouch, Danièle Spehner, Jean-Marc Crance, Anne-Laure Favier

Open Access Publications

No abstract provided.

Somatic Neurofibromatosis Type 1 (Nf1) Inactivation Characterizes Nf1-Associated Pilocytic Astrocytoma, David H. Gutmann, Michael D. Mclellan, Ibrahim Hussain, John W. Wallis, Lucinda L. Fulton, Robert S. Fulton, Vincent Magrini, Ryan Demeter, Todd Wylie, Cyriac Kandoth, Jeffrey R. Leonard, Abhijit Guha, Christopher A. Miller, Li Ding, Elaine R. Mardis

Open Access Publications

No abstract provided.

Evolutionarily Novel Functional Networks In The Human Brain?, Dante Mantini, Maurizio Corbetta, Gian Luca Romani, Guy A. Orban, Wim Vanduffel

Open Access Publications

Primate evolution has been accompanied by complex reorganizations in brain anatomy and function. Little is known, however, about the relationship between anatomical and functional changes induced through primate evolution. Using functional magnetic resonance imaging, we assessed spatial and temporal correspondences of cortical networks in humans and monkeys. We provided evidence for topologically and functionally correspondent networks in sensory-motor and attention regions. More specifically, we revealed a possible monkey equivalent of the human ventral attention network. For other human networks, such as the language and the default-mode networks, we detected topological correspondent networks in the monkey, but with different functional signatures. …

The Disruption Of Celf6, A Gene Identified By Translational Profiling Of Serotonergic Neurons, Results In Autism-Related Behaviors, Joseph D. Dougherty, Susan E. Maloney, David F. Wozniak, Michael A. Rieger, Lisa Sonnenblick, Giovanni Coppola, Nathaniel G. Mahieu, Juliet Zhang, Jinlu Cai, Gary J. Patti, Brett S. Abrahams, Daniel H. Geschwind, Nathaniel Heintz

Open Access Publications

The immense molecular diversity of neurons challenges our ability to understand the genetic and cellular etiology of neuropsychiatric disorders. Leveraging knowledge from neurobiology may help parse the genetic complexity: identifying genes important for a circuit that mediates a particular symptom of a disease may help identify polymorphisms that contribute to risk for the disease as a whole. The serotonergic system has long been suspected in disorders that have symptoms of repetitive behaviors and resistance to change, including autism. We generated a bacTRAP mouse line to permit translational profiling of serotonergic neurons. From this, we identified several thousand serotonergic-cell expressed transcripts, …

Community-Based Argentine Tango Dance Program Is Associated With Increased Activity Participation Among Individuals With Parkinson's Disease, Erin R. Foster, Laura Golden, Ryan P. Duncan, Gammon M. Earhart

Physical Therapy Faculty Publications

No abstract provided.

Spatiotemporal Clustering Of The Epigenome Reveals Rules Of Dynamic Gene Regulation, Pengfei Yu, Shu Xiao, Xiaoyun Xin, Chun-Xiao Song, Wei Huang, Darina Mcdee, Tetsuya Tanaka, Ting Wang, Chuan He, Sheng Zhong

Open Access Publications

No abstract provided.

Brca1 Loss Activates Cathepsin L–Mediated Degradation Of 53bp1 In Breast Cancer Cells, David A. Grotsky, Ignacio Gonzalez-Suarez, Anna Novell, Martin A. Neumann, Sree C. Yaddanapudi, Monica Croke, Montserrat Martinez-Alonso, Abena B. Redwood, Sylvia Ortega-Martinez, Zhihui Feng, Enrique Lerma, Teresa Ramon Y Cajal, Junran Zhang, Xavier Matias-Guiu, Adriana Dusso, Susana Gonzalo

Open Access Publications

No abstract provided.

Management Of Chronic Pain In Elderly Frail Patients Finding A Suitable Personalized Method Of Control, Rahul Rastogi, Brian D. Meek

Open Access Publications

No abstract provided.

Robot-Assisted Partial Nephrectomy: Off-Clamp Technique, Gurdarshan S. Sandhu, Eric H. Kim, Youssef S. Tanagho, Sam B. Bhayani, R. Sherburne Figenshau

Open Access Publications

No abstract provided.

Pacs Bulletin 2013-2014, Program In Audiology And Communication Sciences

PACS News

No abstract provided.

Identification Of A Pan-Cancer Oncogenic Microrna Superfamily Anchored By A Central Core Seed Motif, Mark P. Hamilton, Kimal Rajapakshe, Sean M. Hartig, Boris Reva, Michael D. Mclellan, Cyriac Kandoth, Li Ding, Travis I. Zack, Preethi H. Gunaratne, David A. Wheeler, Cristian Coarfa, Sean E. Mcguire

Open Access Publications

No abstract provided.

Rapid-Selex For Rna Aptamers, Kylan Szeto, David R. Latulippe, Abdullah Ozer, John M. Pagano, Brian S. White, David Shalloway, John T. Lis, Harold G. Craighead

Open Access Publications

No abstract provided.

Speech-Evoked Auditory Brainstem Response In Children With Unilateral Hearing Loss, Megan E. Carter

Independent Studies and Capstones

Speech-evoked auditory brainstem responses (ABRs) and speech recognition measures were evaluated in children with unilateral hearing loss (UHL) and normal hearing (NH). There were significant differences between the two hearing groups for several components of the response in quiet and in noise. Children with UHL performed worse than children with NH on all speech recognition measures in quiet and in noise.

Role Of Trem1-Dap12 In Renal Inflammation During Obstructive Nephropathy, Alessandra Tammaro, Ingrid Stroo, Elena Rampanelli, Froilan Blank, Loes M. Butter, Nike Claessen, Toshiyuki Takai, Marco Colonna, Jaklien C. Leemans, Sandrine Florquin, Mark C. Dessing

Open Access Publications

No abstract provided.

Functional Intersection Of Atm And Dna-Dependent Protein Kinase Catalytic Subunit In Coding End Joining During V(D)J Recombination, Baeck-Seung Lee, Eric J. Gapud, Yair Dorsett, Andrea Bredemeyer, Rosmy George, Oleg Osipovich, Eugene M. Oltz, Barry P. Sleckman, Et Al

Open Access Publications

No abstract provided.

Detection Of Rapalog-Mediated Therapeutic Response In Renal Cancer Xenografts Using (64)Cu-Bevacizumab Immunopet, Albert J. Chang, Rebecca Sohn, Zhi Hong Lu, Jeffrey M. Arbeit, Suzanne E. Lapi

Open Access Publications

No abstract provided.

A Fixed-Dose Randomized Controlled Trial Of Olanzapine For Psychosis In Parkinson Disease, Michelle J. Nichols, Johanna M. Hartlein, Meredith G.A Eicken, Brad A. Racette, Kevin J. Black

Psychiatry Faculty Publications

No abstract provided.

Comparison Of Hearing Levels Of College Music And Non-Music Majors: Does Rehearsal Noise Affect Hearing Health?, Erin F. Hawkins

Independent Studies and Capstones

No abstract provided.

Normal Cochlear Lateral Wall Permeability To Fluorescent Macromolecules, Veronica E. Henson

Independent Studies and Capstones

Damage to the stria vascularis resulting in leakage of macromolecules from the capillaries has been indicated in research as undermining the endocochlear potential. Results indicate normal paracellular diffusion and caveolae-mediated transcytosis, suggesting normal permeability that does not necessitate pathology or undermine the endocochlear potential.

Vulnerabilities And Vulnerable Populations: The Case Of Women And Obstetric Fistulas, Lewis Wall

2013 Ethics Series: Research Literacy and Informed Consent

No abstract provided.

Endocrine Therapy Resistant Esr1 Variants Revealed By Genomic Characterization Of Breast Cancer Derived Xenografts, Shunqiang Li, Dong Shen, Jieya Shao, Robert Crowder, Jeremy Hoog, Charles Lu, Li Ding, Obi L. Griffith, Christopher Miller, Dave Larson, Robert S. Fulton, Michelle Harrison, Tom Mooney, Joshua F. Mcmichael, Jingqin Luo, Yu Tao, Rodrigo Goncalves, Christopher Schlosberg, Jeffrey F. Hiken, Laila Saied, Therese Giuntoli, Caroline Bumb, Crystal Cooper, Robert T. Kitchens, Austin Lin, Chanpheng Phommaly, Sherri R. Davies, Jin Zhang, Megha Shyam Kavuri, Yi Yu Dong, Cynthia Ma, Timothy Pluard, Michael Naughton, Ron Bose, Rama Suresh, Reida Mcdowell, Loren Michel, Rebecca Aft, William Gillanders, Katherine Deschryver, Richard K. Wilson, John R. Edwards, Christopher Maher, Elaine R. Mardis, Matthew J. Ellis, Et Al

Peer-Reviewed Publications

No abstract provided.

An Emerging Place For Lung Cancer Genomics In 2013, Marissa G. Daniels, Rayleen V. Bowman, Ian A. Yang, Ramaswamy Govindan, Kwun M. Fong

Open Access Publications

No abstract provided.

Prolonged Systemic Inflammation Persistently Modifies Synaptic Plasticity In The Hippocampus: Modulation By The Stress Hormones, Nicola Maggio, Efrat Shavit-Stein, Amir Dori, Ilan Blatt, Joab Chapman

Open Access Publications

No abstract provided.