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Molecular And Histologic Studies Of The Amygdala And Reward Circuits In Rhesus Macaques (Macaca Mulatta) With Self-Injurious Behavior (Sib), Jackie Barua Jun 2026

Molecular And Histologic Studies Of The Amygdala And Reward Circuits In Rhesus Macaques (Macaca Mulatta) With Self-Injurious Behavior (Sib), Jackie Barua

Doctoral Dissertations

Self-injurious behavior (SIB), also known as non-suicidal self-injury (NSSI), is characterized by deliberate infliction of harming one’s own body tissues without committing suicide, and persists in a group of captive rhesus macaques despite an enhanced enrichment program and pharmacological intervention with diazepam. The aim of this dissertation was to identify the neurobiological underpinnings of SIB by combining RNA-seq guided transcriptomic discovery and targeted candidate gene validation with unbiased histological and imaging analysis. The secondary aim was to employ a complementary mouse model to investigate the endogenous opioid system in response to diazepam. The amygdala transcriptome of primates with SIB (n …


Development Of Artificial Intelligence Based Geophysical Technique For Unconventional Resource Exploration, S M Shamsul Hoque Jun 2026

Development Of Artificial Intelligence Based Geophysical Technique For Unconventional Resource Exploration, S M Shamsul Hoque

Doctoral Dissertations

Unconventional shale resources have become an important source of oil and gas in the United States, but their characterization remains challenging because of strong heterogeneity and complex elastic and geomechanical behavior. Important properties, such as total organic carbon (TOC) and brittleness, play a key role in evaluating source quality, reservoir behavior, development potential, and subsurface storage suitability. This dissertation develops artificial intelligence-based geophysical techniques to improve unconventional resource exploration and characterization by integrating seismic attributes, well-log data, deep learning, multicomponent seismic registration, and joint PP-PS inversion. A TOC estimation technique is developed and applied to both the Tuscaloosa Marine Shale …


Seeing Through Similar Eyes: How Social Identity Shapes Reinterpretation Of Ambiguous Stimuli, Eli Bailit Jun 2026

Seeing Through Similar Eyes: How Social Identity Shapes Reinterpretation Of Ambiguous Stimuli, Eli Bailit

Cognitive Science Senior Theses

Identical sensory input can lead to a variety of subjective experiences and interpretations. In the face of such ambiguity, we often turn to our social context. Does the identity of the person providing an alternative interpretation to an ambiguous stimulus impact someone’s likelihood to adopt it? This study examined whether perceived interpersonal similarity modulates reinterpretation of ambiguous visual stimuli. Thirty Dartmouth undergraduates completed a modified “MadLibs” paradigm in which they generated initial interpretations of ambiguous photographs, indicated their confidence in their interpretations, then decided how much to update those interpretations upon viewing an alternative sourced from an individual of varying …


Identifying Preferred Toothpaste And Improving Toothbrushing Participation In Autistic Individuals, Taylor Bakalar Jun 2026

Identifying Preferred Toothpaste And Improving Toothbrushing Participation In Autistic Individuals, Taylor Bakalar

Doctoral Dissertations - College of Arts and Sciences

Research that assessed the prevalence of oral health disorders among those with autism spectrum disorder (ASD) found that behavior and environmental variables played a role in deteriorated dental hygiene in some patients with ASD. Behavior analytic interventions have been used to increase participation with dental exams and daily toothbrushing skills (Duhanyan et al., 2019). The current study seeks to extend Duhanyan et al. (2019) through the implementation of a modified single-stimulus preference assessment to identify a preferred toothpaste by evaluating increased percentage of participation with experimenter-implemented toothbrushing. For all participants, the SSPA identified at least one toothpaste flavor that increased …


Novel Oral Fluid Drug Screening Device Evaluation, Sarah Jenkins Jun 2026

Novel Oral Fluid Drug Screening Device Evaluation, Sarah Jenkins

ETDs from 2020-2029

Oral fluid (OF) has been determined comparable to blood while being a more accurate specimen to reflect recent use than urine. OF roadside testing devices utilize the ease of access and toxicological information provided by OF. These devices are designed to be used as a roadside screening device that can detect the presence of drugs. In 2018, Alabama was the first state in America to implement a comprehensive state OF drug testing program for screening and laboratory testing. At the current moment, there are five approved devices for use in Alabama. Part of the development of the program involved evaluating …


Severity Of Deficit In Skeletal Muscle Lipid Metabolism Invokes Unique Adaptive Responses In Dietary Lipid Intake And Absorption, Victoria Datta Jun 2026

Severity Of Deficit In Skeletal Muscle Lipid Metabolism Invokes Unique Adaptive Responses In Dietary Lipid Intake And Absorption, Victoria Datta

Masters Theses

Skeletal muscle plays a central role in whole-body lipid metabolism through mitochondrial and peroxisomal fatty acid oxidation (FAO). When skeletal muscle lipid metabolism is impaired, whole-body adaptations occur to maintain metabolic homeostasis. We hypothesized that limiting skeletal muscle lipid metabolism through mitochondria and/or peroxisomes would trigger adaptive responses to reduce dietary lipid intake and/or absorption with the most robust changes coinciding with deficit severity. Mice were generated with skeletal muscle-specific deletion of 1) carnitine palmitoyltransferase 1b (Cpt1bM-/-) to limit mitochondrial FAO, 2) peroxin 5 (Pex5M-/-) to impair peroxisomal FAO, and 3) both Cpt1b and Pex5 (DKO). Results were compared to …


Investigating Patterns Of (Mal)Adaptation In Two Dominant Cajun Prairie Grasses: Schizachyrium Scoparium And Panicum Virgatum, Braden Isaiah Doucet Jun 2026

Investigating Patterns Of (Mal)Adaptation In Two Dominant Cajun Prairie Grasses: Schizachyrium Scoparium And Panicum Virgatum, Braden Isaiah Doucet

Masters Theses

Local adaptation is assumed to be prevalent within natural populations, but anthropogenic climate change and habitat destruction have been demonstrated to cause maladaptation. This thesis examines patterns of adaptation within two dominant grass species of our local Cajun Prairie ecosystem, Panicum virgatum and Schizachyrium scoparium. Using a provenance common garden study, our results reveal how climate change and habitat destruction have altered the patterns of adaptation within local populations. Chapter 1 examines how source climate and geographic distance predicts population fitness. Chapter 2 examines the type, magnitude, and direction of selection acting on key ecological traits of both species, as …


Hyperdimensional Computing For Edge And Mobile Devices, Colin Eddy Dupuis Jun 2026

Hyperdimensional Computing For Edge And Mobile Devices, Colin Eddy Dupuis

Masters Theses

This thesis presents a set of four Hyperdimensional Computing (HDC) frameworks and their Android application implementations to evaluate efficiency and feasibility on resource-constrained devices. These proposed methods target a range of application domains, including wearable health monitoring, mobile malware detection, and activity recognition utilizing both computer vision and multiple sensor streams as input. The proposed frameworks utilize HDC’s simple, lightweight arithmetic operations to convert raw data into high-dimensional representations for use in both binary and multi-class classification schemes. Each method utilizes unique encoding techniques tailored for each use case, demonstrating the flexible nature and specialization HDC offers as an emerging …


Emerging Catalysts And System Designs For High-Current-Density Co2 Electroreduction To Multicarbon Fuels And Chemicals Toward Industrial-Scale Applications, Godwin Uche Edor Jun 2026

Emerging Catalysts And System Designs For High-Current-Density Co2 Electroreduction To Multicarbon Fuels And Chemicals Toward Industrial-Scale Applications, Godwin Uche Edor

Masters Theses

Electrochemical CO2 reduction (eCO2RR) offers a sustainable route to convert CO2 into value-added fuels and chemicals, particularly multicarbon (C2+) products due to their higher energy density and economic value compared to C1 counterparts. Industrial adoption of eCO2RR technology is hindered by the difficulty in stably reaching superior Faradaic efficiency (FE) for C2+ products at ≥ 200 mA cm-2 at low applied overpotential due to sluggish C–C coupling kinetics, competing reactions, and catalyst instability. Hence, we examine the recent advances in eCO2RR catalyst engineering strategies, such as nanostructural and electronic modifications of Cu-based catalysts (e.g., interfacial, surface, facet, and defect engineering, …


Beyond Social Disconnection: The Unique Relationship Between Existential Loneliness And Depression, Lauren Beatrice Edwards Jun 2026

Beyond Social Disconnection: The Unique Relationship Between Existential Loneliness And Depression, Lauren Beatrice Edwards

Masters Theses

Depression and loneliness are among the most pressing mental health concerns in the United States, yet their relationship remains incompletely understood. Research has extensively examined social-emotional, or general, loneliness. However, existential loneliness (EL), the felt sense of being fundamentally alone in one's existence, has remained on the theoretical periphery. This study examined EL as a meaningfully distinct dimension of loneliness and explored its unique relationship with depressive symptoms in a sample of 301 U.S. adults recruited via Prolific. A joint exploratory factor analysis confirmed that EL and general loneliness are empirically separable dimensions of loneliness. Regression analyses revealed that EL …


Micro-Hyperspectral Imaging Of Phytoplankton Enables Deconvolution Of Mixed Communities For Spaceborne Hyperspectral Remote Sensing, Chisom Okwuchi Emeghiebo Jun 2026

Micro-Hyperspectral Imaging Of Phytoplankton Enables Deconvolution Of Mixed Communities For Spaceborne Hyperspectral Remote Sensing, Chisom Okwuchi Emeghiebo

Masters Theses

Characterizing phytoplankton diversity is critical for large-scale biodiversity monitoring and harmful algal bloom (HAB) detection. Here, we present a micro hyperspectral imaging method to characterize reflectance signatures, for the first time across major phytoplankton groups. Spectral variability among taxa in laboratory cultures is interpreted using algal pigment and absorption analyses, demonstrating that pigment composition and absorption govern reflectance features. Chlorophytes and cryptophytes exhibit distinct spectral signatures and are readily distinguishable, whereas diatoms and dinoflagellates show greater spectral similarity, with differentiation relying on subtle reflectance features associated with chlorophyll c₁c₂ near ~463 nm and within 620–650 nm. We further applied this …


Geological Carbon Storage In Deep, Low Permeable Shale Reservoirs: Insights From The Haynesville Formation, Louisiana, Himakshi Goswami Jun 2026

Geological Carbon Storage In Deep, Low Permeable Shale Reservoirs: Insights From The Haynesville Formation, Louisiana, Himakshi Goswami

Masters Theses

As global initiatives to mitigate greenhouse gas emissions intensify, depleted unconventional shale gas formations have emerged as critical candidates for large-scale geological carbon storage (GCS). This study investigates the feasibility, dynamic trapping mechanisms, and operational optimization of CO₂ sequestration in deep, low-permeability shale reservoirs, using the Upper Jurassic Haynesville Shale in northwest Louisiana as a comprehensive case study. Compositional reservoir simulation (CMG GEM 2021.10) was performed using the SPE Haynesville dataset, with CO₂ injected at a rate of 10,000 ft³/day across single and multiple depth intervals spanning 11,290–11,314 feet. Results demonstrate that multi-depth injection significantly improves residual trapping, reduces buoyancy-driven …


Evaluating The Impact Of Invasive Carp On Atchafalaya River Zooplankton Community Structure, Bryce Lavergne Jun 2026

Evaluating The Impact Of Invasive Carp On Atchafalaya River Zooplankton Community Structure, Bryce Lavergne

Masters Theses

Invasive carp (Hypopthalmichthys spp.) is a generalist filter feeder that has established itself across the Mississippi Watershed of the United States and caused harm to native fish species through depletion of a shared resource, causing a decline in zooplankton density and body size. This study analyzes the impact of larval invasive carp on zooplankton community structure between drought and non-drought years and an environmental gradient in the Atchafalaya River Basin. Larval carp and zooplankton density and size were sampled using net tows and correlated with environmental parameters measured in 2023 and 2024. Results showed that zooplankton density and size were …


Viral Visions Of Femininity: A Visual Thematic Analysis Of Trending Tradwife Imagery On Instagram, Phoebe L. Lim Jun 2026

Viral Visions Of Femininity: A Visual Thematic Analysis Of Trending Tradwife Imagery On Instagram, Phoebe L. Lim

Masters Theses

This study uses visual thematic analysis and a semiotics lens to examine how trending tradwife content on Instagram constructs domestic femininity through recurring signifiers of whiteness, homemaking, motherhood, and hyperfeminine aesthetics. Current rhetorical analysis of the tradwife movement argues that the imagery of sweet, nostalgic traditionalism functions to mask visual and semiotic codes associated with patriarchal hierarchies, anti-feminism, pronatalism, and alt-right ideologies (Proctor, 2022). Drawing on the theoretical models of Saussure, Peirce, and Barthes (1972), this research analyzes how strategically curated visuals of domesticity and femininity function as ideological signifiers within digital culture. Analysis of 100 posts under #tradwife found …


The Effect Of Perceived Support On Black College Students' Sense Of Belonging, Jamillia Domani Mckinley Jun 2026

The Effect Of Perceived Support On Black College Students' Sense Of Belonging, Jamillia Domani Mckinley

Masters Theses

Black college students oftentimes navigate higher education environments while managing academic demands alongside racialized stressor that can weaken their sense of belonging. Existing literature and research examined peer relationships, faculty support, and institutional support separately; however, little to no studies considered how these forms of support operate together in shaping belonging. The current study addressed that gap by examining whether perceived peer support, teacher support, and institutional support predict Black students’ sense of belonging in college and university settings. Through the lens of Maslow’s Hierarchy of Needs, belonging was viewed as a foundational need for confidence, connection, growth, and self …


Linking Greenhouse Gas Fluxes And Plant Responses To Saltwater Intrusion Events Using Remote Sensing, Madeline Jean Moore Jun 2026

Linking Greenhouse Gas Fluxes And Plant Responses To Saltwater Intrusion Events Using Remote Sensing, Madeline Jean Moore

Masters Theses

As sea level rise and coastal subsidence increase coastal Louisiana's vulnerability to saltwater intrusion (SWI) events, accurate and rapid monitoring of vegetation responses to these events is becoming increasingly important. In this study, we utilized unmanned aerial vehicle (UAV) multispectral imagery to assess short-term vegetation responses to simulated SWI events in the Visser’s Experimental Wetland Complex in Saint Martinville, Louisiana. Vegetation patches of two common freshwater wetland species, Panicum hemitomon (Maidencane) and Typha domingensis (Southern Cattail), were exposed to 5 ppt salinity for 6-, 10-, and 17-day durations. Multispectral imagery of both species was collected before and after each SWI …


Classifying Storm Surges Along Louisiana Coast Using Machine Learning, Faith Ewere Okunbor Jun 2026

Classifying Storm Surges Along Louisiana Coast Using Machine Learning, Faith Ewere Okunbor

Masters Theses

Storm surges are among the most significant threats to coastal wetlands, causing flooding and saltwater intrusion that alter hydrology, vegetation structure, and long-term ecosystem resilience. Along the Louisiana coast, storm surge effects vary depending on storm behavior, shoreline geometry, and marsh hydrologic connectivity, yet are commonly characterized using broad storm metrics rather than site-specific environmental responses. This study develops a data-driven framework to classify storm surges across coastal Louisiana wetlands using observations from the Coastwide Reference Monitoring System (CRMS). Hourly water-level and salinity time series from twelve hurricanes (2007-2024) were analyzed using a 40-day storm-centered window. Hydrologic and salinity metrics …


Regioselective Tellurination Reactions And Their Utilities, Itunu Comfort Olanrewaju Jun 2026

Regioselective Tellurination Reactions And Their Utilities, Itunu Comfort Olanrewaju

Masters Theses

This thesis provides a comprehensive study of regioselective tellurination and its applications by integrating experimental and computational techniques, with an aim of synthesizing libraries of organotellurium heterocycles. This study addresses existing challenges in regioselective tellurination, such as unpredictable regioselectivity and avoidance of toxic reagents by harnessing intramolecular Te…O coordination and electrophilic aromatic tellurination. This strategy enables the development of previously poorly accessible compounds including benzotellurazinones, 2-acylaminobenzotellurazoles, and previously unknown 2,3-dihydrobenzo [b] oxatelluranes, which were prepared by antiMarkovnikov anti-addition of TeCl4 to C-C triple bonds. Experimental studies were complemented by computational DFT analyses to provide mechanistic and energetic insight into the …


Tinder Troubles: Testing The Motivation-Based Model Of Online Disinhibition In A Mobile Dating App Context, Zachary Schleter Jun 2026

Tinder Troubles: Testing The Motivation-Based Model Of Online Disinhibition In A Mobile Dating App Context, Zachary Schleter

Masters Theses

As individuals turn to dating apps to find romance, friendships, sex, and more, understanding the factors that shape user behavior on these platforms has become increasingly important. Guided by Wen and Miura’s (2023) motivation-based Model of Online Disinhibition, this study examined how individual factors and motives for using Tinder predict online disinhibition and subsequent disinhibited behaviors. Specifically, using an English translation of Wen & Miura’s Multi-dimensional Measure of Online Disinhibition (2024), the study tested whether gender and five Tinder use motives—sexual experience, entertainment, romance, socializing, and distraction—predicted levels of online disinhibition on Tinder and whether online disinhibition, in turn, predicted …


One-On-One Vs. Group Health Coaching: Impact On Weight, Knowledge And Well-Being., Julie Nelson Jun 2026

One-On-One Vs. Group Health Coaching: Impact On Weight, Knowledge And Well-Being., Julie Nelson

Nursing Capstones

This DNP scholarly project completed a retrospective review, comparing the effectiveness of one-on-one versus group-based health and wellness coaching in improving outcomes related to weight loss, health knowledge, and participant perceptions of well-being. The project reviewed existing, de-identified data from adults who previously completed a coaching program focused on healthy behavior change. Coaching was delivered in either a group or one-on-one format, and outcome measures included changes in weight, knowledge of healthy behaviors, and participant reported impressions of overall health and wellness. The aim of the project was to determine if the delivery method of coaching impacts outcomes, thus informing …


Stories From The Pantanal: Documentary Filmmaking And Conservation In A Changing Wetland Landscape, Tobin Yates Jun 2026

Stories From The Pantanal: Documentary Filmmaking And Conservation In A Changing Wetland Landscape, Tobin Yates

Environmental Studies Senior Theses

This thesis pairs a short documentary film, Umbigo do Pantanal, with a written component examining conservation in Brazil's Pantanal wetland. Six days of fieldwork in Mato Grosso in September 2025 centered on Sandro Sebastião Godofredo, a multi-generational Pantaneiro rancher whose 130,000-hectare property is transitioning from intensive cattle operations toward ecosystem-based conservation and ecotourism. Sandro's account, drawn from interviews recorded on his ranch and along the São Lourenço River, anchors a broader argument about the limits of single-species conservation models in the Pantanal. The dominant jaguar-focused approach concentrates ecotourism revenue in a small portion of the wetland while pushing the costs …


Liver Injury From Medications Used For Treating Inflammatory Bowel Disease: The Drug-Induced Liver Injury Network Experience, Harish Gopalakrishna, Jiezhun Gu, Yi-Ju Li, Huiman Barnhart, Dina Halegoua-De Marzio, Herbert L. Bonkovsky, A. Sidney Barritt, Jean P. Molleston, Naga P. Chalasani, Marwan Ghabril Jun 2026

Liver Injury From Medications Used For Treating Inflammatory Bowel Disease: The Drug-Induced Liver Injury Network Experience, Harish Gopalakrishna, Jiezhun Gu, Yi-Ju Li, Huiman Barnhart, Dina Halegoua-De Marzio, Herbert L. Bonkovsky, A. Sidney Barritt, Jean P. Molleston, Naga P. Chalasani, Marwan Ghabril

Division of Gastroenterology and Hepatology Faculty Papers

BACKGROUND: We aimed to investigate and characterise DILI due to approved therapies for inflammatory bowel disease (IBD).

METHODS: Using the Drug-Induced Liver Injury Network (DILIN) prospective study, we evaluated definite, highly likely, or probable DILI attributed to IBD therapies, including use for non-IBD indications (but excluding corticosteroids). HLA allele associations were investigated.

RESULTS: Among 1806 participants, 81 (4.5%) had IBD-agent DILI: 31 biologics (27 infliximab), 35 immunomodulators (31 azathioprine/mercaptopurine), 14 aminosalicylates (11 sulfasalazine) and 1 small molecule (tofacitinib). Median age was 45 years with 75% female and 78% White. Patients with biologic-DILI were younger, had longer latency (median 124 days), …


Jsd: Novel Methodology For Synthetic Data Evaluation, Jeffrey Lane, Scott Wang, Vincent Chang, Bojun Zhang Jun 2026

Jsd: Novel Methodology For Synthetic Data Evaluation, Jeffrey Lane, Scott Wang, Vincent Chang, Bojun Zhang

Computer Science and Engineering Senior Theses

The proliferation of sensitive Personally Identifiable Information (PII) on dark web marketplaces has created an urgent need for robust data protection systems, especially for vulnerable populations such as minors. Traditional PII redaction often fails to identify implicit privacy risks—such as author gender indicators or non-fictional child-related context—hidden within large-scale e-commerce datasets. This paper presents JSD, a dual-stage framework for the detection and protection of sensitive text data. The Detection phase utilizes Transformer and CNN-based architectures and Human-in-the-Loop AI to surpass the "semantic ceiling" of traditional NER approaches, enabling context-aware identification of implicit PII. The Protection phase introduces GASE (Genetic Algorithm …


Academic Senate - Agenda, 06/02/2026, Academic Senate Jun 2026

Academic Senate - Agenda, 06/02/2026, Academic Senate

Academic Senate Agendas

No abstract provided.


Biol A111l:Human Anatomy And Physiology I Laboratory, Jeremy Nettleton Jun 2026

Biol A111l:Human Anatomy And Physiology I Laboratory, Jeremy Nettleton

Publications

A Human Anatomy and Physiology I Lab syllabus with links to open access textbook.


First Course Portfolio For Plpt 803 Fundamentals Of Scientific Discovery, Hernan Garcia-Ruiz Jun 2026

First Course Portfolio For Plpt 803 Fundamentals Of Scientific Discovery, Hernan Garcia-Ruiz

UNL Faculty Course Portfolios

PLPT 803 Fundamentals of Scientific discovery is a new curse in the Department of Plant Pathology at the University of Nebraska-Lincoln. I designed and developed this course from the ground up. Initially, it was offered as a special topic (PLPT 892-014) for four years. PLPT 803 was approved by the College of Agricultural Sciences and Natural Resources curriculum committee in September of 2025. PLPT 803 is unique within the University of Nebraska system and will be offered for the first time in the fall of 2027. The course is designed for students to learn fundamental scientific skills such as scrutinize, …


September 2024 – August 2025 Case Law On American Indians, Thomas P. Schlosser Jun 2026

September 2024 – August 2025 Case Law On American Indians, Thomas P. Schlosser

American Indian Law Journal

No abstract provided.


New Applications Of Cardiopulmonary Exercise Testing Parameters Characterize Age-Related Changes In Exercise Performance During Adolescence, Katerina Kourpas, Takeshi Tsuda Jun 2026

New Applications Of Cardiopulmonary Exercise Testing Parameters Characterize Age-Related Changes In Exercise Performance During Adolescence, Katerina Kourpas, Takeshi Tsuda

Department of Pediatrics Faculty Papers

BACKGROUND: Age-related changes in exercise performance during adolescence are complex because of progressive physical and functional changes, in which multiple factors are involved.

METHODS: Peak and submaximal cardiopulmonary exercise testing (CPET) parameters were studied in healthy children and adolescents.

RESULTS: TTotal 303 subjects were divided into six groups by ages and sex: ≤11 years old (yo) (28/22 for males/females), 12–15 yo (61/98), and ≥16 yo (52/42). Rest and peak heart rate (HR) were comparable in all groups. Absolute peak values of oxygen consumption (˙ VO2), work rate (WR), and oxygen pulse (OP) were higher in older age groups in both …


A Cross-Sectional Analysis Of The Vaginal Microenvironment In Rheumatoid Arthritis, Ali El-Halwagi, Keshia Ferguson, Maryjo Maliekel, Yixuan Zhou, Camille Serchejian, Clare M Robertson, Mallory B Ballard, Lee B Lu, Sobia Khan, Olubunmi O Oladunjoye, Shixia Huang, Sandeep K Agarwal, Kathryn A Patras Jun 2026

A Cross-Sectional Analysis Of The Vaginal Microenvironment In Rheumatoid Arthritis, Ali El-Halwagi, Keshia Ferguson, Maryjo Maliekel, Yixuan Zhou, Camille Serchejian, Clare M Robertson, Mallory B Ballard, Lee B Lu, Sobia Khan, Olubunmi O Oladunjoye, Shixia Huang, Sandeep K Agarwal, Kathryn A Patras

Faculty, Staff and Students Publications

The human microbiota is implicated in the development and progression of rheumatoid arthritis (RA). Given the increased RA burden in women and well-known correlations between the vaginal microbiota and local inflammation, we seek to understand the vaginal microenvironment in the context of RA pathology. Self-collected vaginal swabs and questionnaires on dietary, menstrual, and health information were obtained from 36 RA and 50 demographically-matched control women, 18–63 years of age. Medication regimen, along with disease activity and severity, was captured for the RA cohort. Vaginal swabs were subjected to long-read 16S rRNA gene sequencing, multiplex cytokine analyses, and quantification of rheumatoid …


Harnessing Story To Overcome The Double Empathy Problem Between Autistic And Neurotypical People: Brain-Behavior Relationships, Kate Gifford Jun 2026

Harnessing Story To Overcome The Double Empathy Problem Between Autistic And Neurotypical People: Brain-Behavior Relationships, Kate Gifford

Theses and Dissertations

There is a dearth of information on the physical aspects of the Double Empathy Problem which is the bidirectional challenge of shared empathy and understanding between autistic and neurotypical individuals. Storytelling has been shown as means to facilitate empathy between storytellers and listeners in both neurotypical and autistic populations through behavioral research. Functional near-infrared spectroscopy (fNIRS) is a neuroimaging technique used to evaluate the hemodynamic response in the cortex and can be used to compare hemodynamic responses across multiple individuals (i.e., hyperscanning). The purpose of this study was to examine activation in empathy-related brain regions and assess brain synchrony between …