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Washington University School of Medicine

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Normal Cochlear Lateral Wall Permeability To Fluorescent Macromolecules, Veronica E. Henson Jan 2013

Normal Cochlear Lateral Wall Permeability To Fluorescent Macromolecules, Veronica E. Henson

Independent Studies and Capstones

Damage to the stria vascularis resulting in leakage of macromolecules from the capillaries has been indicated in research as undermining the endocochlear potential. Results indicate normal paracellular diffusion and caveolae-mediated transcytosis, suggesting normal permeability that does not necessitate pathology or undermine the endocochlear potential.


Vulnerabilities And Vulnerable Populations: The Case Of Women And Obstetric Fistulas, Lewis Wall Jan 2013

Vulnerabilities And Vulnerable Populations: The Case Of Women And Obstetric Fistulas, Lewis Wall

2013 Ethics Series: Research Literacy and Informed Consent

No abstract provided.


Endocrine Therapy Resistant Esr1 Variants Revealed By Genomic Characterization Of Breast Cancer Derived Xenografts, Shunqiang Li, Dong Shen, Jieya Shao, Robert Crowder, Jeremy Hoog, Charles Lu, Li Ding, Obi L. Griffith, Christopher Miller, Dave Larson, Robert S. Fulton, Michelle Harrison, Tom Mooney, Joshua F. Mcmichael, Jingqin Luo, Yu Tao, Rodrigo Goncalves, Christopher Schlosberg, Jeffrey F. Hiken, Laila Saied, Therese Giuntoli, Caroline Bumb, Crystal Cooper, Robert T. Kitchens, Austin Lin, Chanpheng Phommaly, Sherri R. Davies, Jin Zhang, Megha Shyam Kavuri, Yi Yu Dong, Cynthia Ma, Timothy Pluard, Michael Naughton, Ron Bose, Rama Suresh, Reida Mcdowell, Loren Michel, Rebecca Aft, William Gillanders, Katherine Deschryver, Richard K. Wilson, John R. Edwards, Christopher Maher, Elaine R. Mardis, Matthew J. Ellis, Et Al Jan 2013

Endocrine Therapy Resistant Esr1 Variants Revealed By Genomic Characterization Of Breast Cancer Derived Xenografts, Shunqiang Li, Dong Shen, Jieya Shao, Robert Crowder, Jeremy Hoog, Charles Lu, Li Ding, Obi L. Griffith, Christopher Miller, Dave Larson, Robert S. Fulton, Michelle Harrison, Tom Mooney, Joshua F. Mcmichael, Jingqin Luo, Yu Tao, Rodrigo Goncalves, Christopher Schlosberg, Jeffrey F. Hiken, Laila Saied, Therese Giuntoli, Caroline Bumb, Crystal Cooper, Robert T. Kitchens, Austin Lin, Chanpheng Phommaly, Sherri R. Davies, Jin Zhang, Megha Shyam Kavuri, Yi Yu Dong, Cynthia Ma, Timothy Pluard, Michael Naughton, Ron Bose, Rama Suresh, Reida Mcdowell, Loren Michel, Rebecca Aft, William Gillanders, Katherine Deschryver, Richard K. Wilson, John R. Edwards, Christopher Maher, Elaine R. Mardis, Matthew J. Ellis, Et Al

Peer-Reviewed Publications

No abstract provided.


An Emerging Place For Lung Cancer Genomics In 2013, Marissa G. Daniels, Rayleen V. Bowman, Ian A. Yang, Ramaswamy Govindan, Kwun M. Fong Jan 2013

An Emerging Place For Lung Cancer Genomics In 2013, Marissa G. Daniels, Rayleen V. Bowman, Ian A. Yang, Ramaswamy Govindan, Kwun M. Fong

Open Access Publications

No abstract provided.


Prolonged Systemic Inflammation Persistently Modifies Synaptic Plasticity In The Hippocampus: Modulation By The Stress Hormones, Nicola Maggio, Efrat Shavit-Stein, Amir Dori, Ilan Blatt, Joab Chapman Jan 2013

Prolonged Systemic Inflammation Persistently Modifies Synaptic Plasticity In The Hippocampus: Modulation By The Stress Hormones, Nicola Maggio, Efrat Shavit-Stein, Amir Dori, Ilan Blatt, Joab Chapman

Open Access Publications

No abstract provided.


Autophagy Activity Contributes To Programmed Cell Death In Caenorhabditis Elegans, Haibin Wang, Qun Lu, Shiya Cheng, Xiaochen Wang, Hong Zhang Jan 2013

Autophagy Activity Contributes To Programmed Cell Death In Caenorhabditis Elegans, Haibin Wang, Qun Lu, Shiya Cheng, Xiaochen Wang, Hong Zhang

Open Access Publications

No abstract provided.


Short Report: Semi-Quantitative Scoring Of An Immunochromatographic Test For Circulating Filarial Antigen, Cedric B. Chesnais, Francois Missamou, Sebastien D.S. Pion, Jean Bopda, Frederic Louya, Andrew C. Majewski, Gary J. Weil, Michel Boussinesq Jan 2013

Short Report: Semi-Quantitative Scoring Of An Immunochromatographic Test For Circulating Filarial Antigen, Cedric B. Chesnais, Francois Missamou, Sebastien D.S. Pion, Jean Bopda, Frederic Louya, Andrew C. Majewski, Gary J. Weil, Michel Boussinesq

Open Access Publications

No abstract provided.


Retinoblastoma Protein Prevents Enteric Nervous System Defects And Intestinal Pseudo-Obstruction, Ming Fu, Solange Landreville, Olga A. Agapova, Luke A. Wiley, Michael Shoykhet, J. William Harbour, Robert O. Heuckeroth Jan 2013

Retinoblastoma Protein Prevents Enteric Nervous System Defects And Intestinal Pseudo-Obstruction, Ming Fu, Solange Landreville, Olga A. Agapova, Luke A. Wiley, Michael Shoykhet, J. William Harbour, Robert O. Heuckeroth

Open Access Publications

No abstract provided.


Washington University In St. Louis Research Toolkit For Medical Student Researchers, Human Research Protection Office, Washington University School Of Medicine In St. Louis Jan 2013

Washington University In St. Louis Research Toolkit For Medical Student Researchers, Human Research Protection Office, Washington University School Of Medicine In St. Louis

HRPO Publications

No abstract provided.


Washington University In St. Louis Irb Meeting Guide, Human Research Protection Office, Washington University School Of Medicine In St. Louis Jan 2013

Washington University In St. Louis Irb Meeting Guide, Human Research Protection Office, Washington University School Of Medicine In St. Louis

HRPO Publications

No abstract provided.


Washington University Human Research Protection Office Training Manual: Expedited Reviewer Specialist, Sarah Fowler-Dixon, Martha F. Jones, Jeanne Velders, Jen Bass-Patino Jan 2013

Washington University Human Research Protection Office Training Manual: Expedited Reviewer Specialist, Sarah Fowler-Dixon, Martha F. Jones, Jeanne Velders, Jen Bass-Patino

HRPO Publications

No abstract provided.


Washington University Human Research Protection Office Training Manual: Irb Analyst, Sarah Fowler-Dixon, Martha F. Jones, Jeanne Velders, Jen Bass-Patino Jan 2013

Washington University Human Research Protection Office Training Manual: Irb Analyst, Sarah Fowler-Dixon, Martha F. Jones, Jeanne Velders, Jen Bass-Patino

HRPO Publications

No abstract provided.


Patient Characteristics But Not Virulence Factors Discriminate Between Asymptomatic And Symptomatic E. Coli Bacteriuria In The Hospital, Jonas Marschall, Marilyn L. Piccirillo, Betsy Foxman, Lixin Zhang, David K. Warren, Jeffrey P. Henderson, Cdc Prevention Epicenters Program Jan 2013

Patient Characteristics But Not Virulence Factors Discriminate Between Asymptomatic And Symptomatic E. Coli Bacteriuria In The Hospital, Jonas Marschall, Marilyn L. Piccirillo, Betsy Foxman, Lixin Zhang, David K. Warren, Jeffrey P. Henderson, Cdc Prevention Epicenters Program

Open Access Publications

No abstract provided.


Detection Of Novel Polyomaviruses, Tspyv, Hpyv6, Hpyv7, Hpyv9 And Mwpyv In Feces, Urine, Blood, Respiratory Swabs And Cerebrospinal Fluid, Rebecca J. Rockett, Theo P. Sloots, Sharleen Bowes, Nicholas O'Neill, Suifang Ye, Jenny Robson, David M. Whiley, Stephen B. Lambert, David Wang, Michael D. Nissen, Seweryn Bialasiewicz Jan 2013

Detection Of Novel Polyomaviruses, Tspyv, Hpyv6, Hpyv7, Hpyv9 And Mwpyv In Feces, Urine, Blood, Respiratory Swabs And Cerebrospinal Fluid, Rebecca J. Rockett, Theo P. Sloots, Sharleen Bowes, Nicholas O'Neill, Suifang Ye, Jenny Robson, David M. Whiley, Stephen B. Lambert, David Wang, Michael D. Nissen, Seweryn Bialasiewicz

Open Access Publications

No abstract provided.


Hypotension Due To Kir6.1 Gain‐Of‐Function In Vascular Smooth Muscle, Anlong Li, Russell H. Knutsen, Haixia Zhang, Patrick Osei-Owusu, Alex Moreno-Dominguez, Theresa M. Harter, Keita Uchida, Maria S. Remedi, Hans H. Dietrich, Carlos Bernal-Mizrachi, Kendall J. Blumer, Robert P. Mecham, Joseph C. Koster, Colin G. Nichols Jan 2013

Hypotension Due To Kir6.1 Gain‐Of‐Function In Vascular Smooth Muscle, Anlong Li, Russell H. Knutsen, Haixia Zhang, Patrick Osei-Owusu, Alex Moreno-Dominguez, Theresa M. Harter, Keita Uchida, Maria S. Remedi, Hans H. Dietrich, Carlos Bernal-Mizrachi, Kendall J. Blumer, Robert P. Mecham, Joseph C. Koster, Colin G. Nichols

Open Access Publications

No abstract provided.


Genomic And Metabolic Disposition Of Non-Obese Type 2 Diabetic Rats To Increased Myocardial Fatty Acid Metabolism, Sriram Devanathan, Samuel T. Nemanich, Attila Kovacs, Nicole Fettig, Robert J. Gropler, Kooresh I. Shoghi Jan 2013

Genomic And Metabolic Disposition Of Non-Obese Type 2 Diabetic Rats To Increased Myocardial Fatty Acid Metabolism, Sriram Devanathan, Samuel T. Nemanich, Attila Kovacs, Nicole Fettig, Robert J. Gropler, Kooresh I. Shoghi

Open Access Publications

No abstract provided.


The Essential, Nonredundant Roles Of Rig-I And Mda5 In Detecting And Controlling West Nile Virus Infection, John S. Errett, Mehul S. Suthar, Aimee Mcmillan, Michael S. Diamond, Michael Gale Jr Jan 2013

The Essential, Nonredundant Roles Of Rig-I And Mda5 In Detecting And Controlling West Nile Virus Infection, John S. Errett, Mehul S. Suthar, Aimee Mcmillan, Michael S. Diamond, Michael Gale Jr

Open Access Publications

No abstract provided.


Sigma-2 Receptor Ligand As A Novel Method For Delivering A Smac Mimetic Drug For Treating Ovarian Cancer, Chenbo Zeng, Suwanna Vangveravong, Jonathan E. Mcdunn, William G. Hawkins, Robert H. Mach Jan 2013

Sigma-2 Receptor Ligand As A Novel Method For Delivering A Smac Mimetic Drug For Treating Ovarian Cancer, Chenbo Zeng, Suwanna Vangveravong, Jonathan E. Mcdunn, William G. Hawkins, Robert H. Mach

Open Access Publications

No abstract provided.


Hypovitaminosis D And Cervical Disk Herniation Among Adults Undergoing Spine Surgery, Geoffrey E. Stoker, Jacob M. Buchowski, Christopher T. Chen, Han J. Kim, Moon S. Park, K. D. Riew Jan 2013

Hypovitaminosis D And Cervical Disk Herniation Among Adults Undergoing Spine Surgery, Geoffrey E. Stoker, Jacob M. Buchowski, Christopher T. Chen, Han J. Kim, Moon S. Park, K. D. Riew

Open Access Publications

No abstract provided.


Cutaneous Myeloid Sarcoma: Natural History And Biology Of An Uncommon Manifestation Of Acute Myeloid Leukemia, M. Yadira Hurley, Grant K. Ghahramani, Stephanie Frisch, Eric S. Armbrecht, Anne C. Lind, Tudung T. Nguyen, Anjum Hassan, Friederike H. Kreisel, John L. Frater Jan 2013

Cutaneous Myeloid Sarcoma: Natural History And Biology Of An Uncommon Manifestation Of Acute Myeloid Leukemia, M. Yadira Hurley, Grant K. Ghahramani, Stephanie Frisch, Eric S. Armbrecht, Anne C. Lind, Tudung T. Nguyen, Anjum Hassan, Friederike H. Kreisel, John L. Frater

Open Access Publications

No abstract provided.


Genomic Correlates Of Relationship Qtl Involved In Fore-Versus Hind Limb Divergence In Mice, Mihaela Pavlicev, Gunter P. Wagner, James P. Noonan, Benedikt Hallgrimsson, James M. Cheverud Jan 2013

Genomic Correlates Of Relationship Qtl Involved In Fore-Versus Hind Limb Divergence In Mice, Mihaela Pavlicev, Gunter P. Wagner, James P. Noonan, Benedikt Hallgrimsson, James M. Cheverud

Open Access Publications

No abstract provided.


Mechanisms Of Hypoglycemia-Associated Autonomic Failure In Diabetes, Philip E. Cryer Jan 2013

Mechanisms Of Hypoglycemia-Associated Autonomic Failure In Diabetes, Philip E. Cryer

Open Access Publications

No abstract provided.


The Unusual Dynamics Of Parasite Actin Result From Isodesmic Polymerization, Kristen M. Skillman, Christopher I. Ma, Daved H. Fremont, Karthikeyan Diraviyam, John A. Cooper, David Sept, L. David Sibley Jan 2013

The Unusual Dynamics Of Parasite Actin Result From Isodesmic Polymerization, Kristen M. Skillman, Christopher I. Ma, Daved H. Fremont, Karthikeyan Diraviyam, John A. Cooper, David Sept, L. David Sibley

Open Access Publications

No abstract provided.


Three Dimensional Structure Prediction Of Fatty Acid Binding Site On Human Transmembrane Receptor Cd36, Zineb Tarhda, Oussama Semlali, Anas Kettani, Ahmed Moussa, Nada A. Abumrad, Azeddine Ibrahimi Jan 2013

Three Dimensional Structure Prediction Of Fatty Acid Binding Site On Human Transmembrane Receptor Cd36, Zineb Tarhda, Oussama Semlali, Anas Kettani, Ahmed Moussa, Nada A. Abumrad, Azeddine Ibrahimi

Open Access Publications

No abstract provided.


P19(Arf) And Ras(V12) Offer Opposing Regulation Of Dhx33 Translation To Dictate Tumor Cell Fate, Yandong Zhang, Anthony J. Saporita, Jason D. Weber Jan 2013

P19(Arf) And Ras(V12) Offer Opposing Regulation Of Dhx33 Translation To Dictate Tumor Cell Fate, Yandong Zhang, Anthony J. Saporita, Jason D. Weber

Open Access Publications

No abstract provided.


Neutrophils Control The Magnitude And Spread Of The Immune Response In A Thromboxane A2-Mediated Process, Chiao-Wen Yang, Emil R. Unanue Jan 2013

Neutrophils Control The Magnitude And Spread Of The Immune Response In A Thromboxane A2-Mediated Process, Chiao-Wen Yang, Emil R. Unanue

Open Access Publications

Neutrophils are obligate cells entering lymph nodes shortly after immunization with protein antigens in adjuvants, starting during the first hour and continuing for several days in two distinct waves. Previously, we demonstrated the strong suppressive effects of neutrophils on CD4 T cell and B cell responses, using either neutrophil-depleting antibodies or genetically neutropenic mice. In this study, we find that neutrophils are the major cells controlling the spread of T cell responses to distal lymph nodes. Although in the presence of neutrophils, ∼75% of the response was restricted to the draining node, in their absence, most of the response was …


Retracted Article: The Bcl11a Transcription Factor Directly Activates Rag Gene Expression And V(D)J Recombination, Baeck-Seung Lee, Joseph D. Dekker, Bum-Kyu Lee, Vishwanath R. Iyer, Barry P. Sleckman, Arthur L. Shaffer Iii, Gregory C. Ippolito, Philip W. Tucker Jan 2013

Retracted Article: The Bcl11a Transcription Factor Directly Activates Rag Gene Expression And V(D)J Recombination, Baeck-Seung Lee, Joseph D. Dekker, Bum-Kyu Lee, Vishwanath R. Iyer, Barry P. Sleckman, Arthur L. Shaffer Iii, Gregory C. Ippolito, Philip W. Tucker

Open Access Publications

No abstract provided.


Aberrations And Their Correction In Light-Sheet Microscopy: A Low-Dimensional Parametrization, Diwakar Turaga, Timothy E. Holy Jan 2013

Aberrations And Their Correction In Light-Sheet Microscopy: A Low-Dimensional Parametrization, Diwakar Turaga, Timothy E. Holy

Open Access Publications

No abstract provided.


Cms: A Web-Based System For Visualization And Analysis Of Genome-Wide Methylation Data Of Human Cancers, Fei Gu, Mark S. Doderer, Yi-Wen Huang, Juan C. Roa, Paul J. Goodfellow, E. Lynette Kizer, Tim H. M. Huang, Yidong Chen Jan 2013

Cms: A Web-Based System For Visualization And Analysis Of Genome-Wide Methylation Data Of Human Cancers, Fei Gu, Mark S. Doderer, Yi-Wen Huang, Juan C. Roa, Paul J. Goodfellow, E. Lynette Kizer, Tim H. M. Huang, Yidong Chen

Open Access Publications

No abstract provided.


The Role Of The Immune Response In Age-Related Macular Degeneration, Scott M. Whitcup, Akrit Sodhi, John P. Atkinson, V Michael Holers, Debasish Sinha, Barbel Rohrer, Andrew D. Dick Jan 2013

The Role Of The Immune Response In Age-Related Macular Degeneration, Scott M. Whitcup, Akrit Sodhi, John P. Atkinson, V Michael Holers, Debasish Sinha, Barbel Rohrer, Andrew D. Dick

Open Access Publications

No abstract provided.