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Washington University School of Medicine

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Natural History Of Plasmodium Odocoilei Malaria Infection In Farmed White-Tailed Deer, Ann M. Guggisberg, Katherine A. Sayler, Samantha M. Wisely, Audrey R. Odom John Jan 2018

Natural History Of Plasmodium Odocoilei Malaria Infection In Farmed White-Tailed Deer, Ann M. Guggisberg, Katherine A. Sayler, Samantha M. Wisely, Audrey R. Odom John

Open Access Publications

No abstract provided.


Superficieibacter Electus Gen. Nov., Sp. Nov., An Extended-Spectrum Β-Lactamase Possessing Member Of The Enterobacteriaceae Family, Isolated From Intensive Care Unit Surfaces, Robert F. Potter, Alaric W. D-Souza, Meghan A. Wallace, Angela Shupe, Sanket Patel, Danish Gul, Jennie H. Kwon, Wandy Beatty, Saadia Andleeb, Carey-Ann D. Burnham, Gautam Dantas Jan 2018

Superficieibacter Electus Gen. Nov., Sp. Nov., An Extended-Spectrum Β-Lactamase Possessing Member Of The Enterobacteriaceae Family, Isolated From Intensive Care Unit Surfaces, Robert F. Potter, Alaric W. D-Souza, Meghan A. Wallace, Angela Shupe, Sanket Patel, Danish Gul, Jennie H. Kwon, Wandy Beatty, Saadia Andleeb, Carey-Ann D. Burnham, Gautam Dantas

Open Access Publications

No abstract provided.


Femoral Osteomyelitis Caused By Cladophialophora In A Patient Without Known Immunocompromise, Nirbhary S. Jain, Christopher B. Horn, Adrian A. Coleoglou Centeno, Obeid N. Ilahi, John E. Mazuski, Grant V. Boccichio, Laurie J. Punch Jan 2018

Femoral Osteomyelitis Caused By Cladophialophora In A Patient Without Known Immunocompromise, Nirbhary S. Jain, Christopher B. Horn, Adrian A. Coleoglou Centeno, Obeid N. Ilahi, John E. Mazuski, Grant V. Boccichio, Laurie J. Punch

Open Access Publications

No abstract provided.


Lysmd3 Is A Type Ii Membrane Protein Without An In Vivo Role In The Response To A Range Of Pathogens, Christine C. Yokoyama, Megan T. Baldridge, Daisy W. Leung, Guoyan Zhao, Chandni Desai, Ta-Chiang Liu, Jeremy P. Huynh, Jacqueline M. Kimmey, Camaron R. Hole, Rachel A. Idol, Sunmin Park, Caihong Wang, Ashley Viehmann Milam, Scott A. Handley, Indira U. Mysorekar, Paul M. Allen, Mary C. Dinauer, Tamara L. Doering, Christina L. Stallings, Gaya K. Amarasinghe, Craig A. Micchelli, Herbert W. Virgin, Et Al. Jan 2018

Lysmd3 Is A Type Ii Membrane Protein Without An In Vivo Role In The Response To A Range Of Pathogens, Christine C. Yokoyama, Megan T. Baldridge, Daisy W. Leung, Guoyan Zhao, Chandni Desai, Ta-Chiang Liu, Jeremy P. Huynh, Jacqueline M. Kimmey, Camaron R. Hole, Rachel A. Idol, Sunmin Park, Caihong Wang, Ashley Viehmann Milam, Scott A. Handley, Indira U. Mysorekar, Paul M. Allen, Mary C. Dinauer, Tamara L. Doering, Christina L. Stallings, Gaya K. Amarasinghe, Craig A. Micchelli, Herbert W. Virgin, Et Al.

Open Access Publications

No abstract provided.


Capillaria Ova And Diagnosis Of Trichuris Trichiura Infection In Humans By Kato-Katz Smear, Liberia, Kerstin Fischer, Abakar Gankpala, Lincoln Gankpala, Fatorma K. Bolay, Kurt C. Curtis, Gary J. Weil, Peter U. Fischer Jan 2018

Capillaria Ova And Diagnosis Of Trichuris Trichiura Infection In Humans By Kato-Katz Smear, Liberia, Kerstin Fischer, Abakar Gankpala, Lincoln Gankpala, Fatorma K. Bolay, Kurt C. Curtis, Gary J. Weil, Peter U. Fischer

Open Access Publications

No abstract provided.


Catheter Removal And Outcomes Of Multidrug-Resistant Central-Line-Associated Bloodstream Infection, Jason P. Burnham, Rebecca P. Rojek, Marin H. Kollef Jan 2018

Catheter Removal And Outcomes Of Multidrug-Resistant Central-Line-Associated Bloodstream Infection, Jason P. Burnham, Rebecca P. Rojek, Marin H. Kollef

Open Access Publications

No abstract provided.


Shea Neonatal Intensive Care Unit (Nicu) White Paper Series: Practical Approaches To Clostridioides Difficile Prevention, Thomas J. Sandora, Kristina K. Bryant, Joseph B. Cantey, Alexis M. Elward, Deborah S. Yokoe, Allison H. Bartlett Jan 2018

Shea Neonatal Intensive Care Unit (Nicu) White Paper Series: Practical Approaches To Clostridioides Difficile Prevention, Thomas J. Sandora, Kristina K. Bryant, Joseph B. Cantey, Alexis M. Elward, Deborah S. Yokoe, Allison H. Bartlett

Open Access Publications

No abstract provided.


Automated Real-Time Collection Of Pathogen-Specific Diagnostic Data: Syndromic Infectious Disease Epidemiology, Gregory A. Storch, Et Al Jan 2018

Automated Real-Time Collection Of Pathogen-Specific Diagnostic Data: Syndromic Infectious Disease Epidemiology, Gregory A. Storch, Et Al

Open Access Publications

No abstract provided.


Mouse Microbiota Models: Comparing Germ-Free Mice And Antibiotics Treatment As Tools For Modifying Gut Bacteria, Elizabeth A. Kennedy, Katherine Y. King, Megan T. Baldridge Jan 2018

Mouse Microbiota Models: Comparing Germ-Free Mice And Antibiotics Treatment As Tools For Modifying Gut Bacteria, Elizabeth A. Kennedy, Katherine Y. King, Megan T. Baldridge

Open Access Publications

No abstract provided.


Population Structure, Antibiotic Resistance, And Uropathogenicity Of Klebsiella Variicola, Robert F. Potter, William Lainhart, Joy Twentyman, Meghan A. Wallace, Bin Wang, Carey-Ann D. Burnham, David A. Rosen, Gautam Dantas Jan 2018

Population Structure, Antibiotic Resistance, And Uropathogenicity Of Klebsiella Variicola, Robert F. Potter, William Lainhart, Joy Twentyman, Meghan A. Wallace, Bin Wang, Carey-Ann D. Burnham, David A. Rosen, Gautam Dantas

Open Access Publications

No abstract provided.


Peli1 Facilitates Virus Replication And Promotes Neuroinflammation During West Nile Virus Infection, Lauren L. Vollmer, Robyn S. Klein, Et Al Jan 2018

Peli1 Facilitates Virus Replication And Promotes Neuroinflammation During West Nile Virus Infection, Lauren L. Vollmer, Robyn S. Klein, Et Al

Open Access Publications

No abstract provided.


Association Of Immune Response With Efficacy And Safety Outcomes In Adults With Phenylketonuria Administered Pegvaliase In Phase 3 Clinical Trials, Soumi Gupta, Kelly Lau, Cary O. Harding, Gillian Shepherd, Ryan Boyer, John P. Atkinson, Vijaya Knight, Joy Olbertz, Kevin Larimore, Zhonghu Gu, Mingjin Li, Orli Rosen, Stephen J. Zoog, Haoling H. Weng, Becky Shweighardt Jan 2018

Association Of Immune Response With Efficacy And Safety Outcomes In Adults With Phenylketonuria Administered Pegvaliase In Phase 3 Clinical Trials, Soumi Gupta, Kelly Lau, Cary O. Harding, Gillian Shepherd, Ryan Boyer, John P. Atkinson, Vijaya Knight, Joy Olbertz, Kevin Larimore, Zhonghu Gu, Mingjin Li, Orli Rosen, Stephen J. Zoog, Haoling H. Weng, Becky Shweighardt

Open Access Publications

No abstract provided.


Impact Of Amoxicillin-Clavulanate Followed By Autologous Fecal Microbiota Transplantation On Fecal Microbiome Structure And Metabolic Potential, Christopher Bulow, Amy Langdon, Tiffany Hink, Meghan Wallace, Kimberly A. Reske, Sanket Patel, Xiaoqing Sun, Sondra Seiler, Susan Jones, Jennie H. Kwon, Carey-Ann D. Burnham, Gautam Dantas, Erik R. Dubberke, Cdc Prevention Epicenter Program Jan 2018

Impact Of Amoxicillin-Clavulanate Followed By Autologous Fecal Microbiota Transplantation On Fecal Microbiome Structure And Metabolic Potential, Christopher Bulow, Amy Langdon, Tiffany Hink, Meghan Wallace, Kimberly A. Reske, Sanket Patel, Xiaoqing Sun, Sondra Seiler, Susan Jones, Jennie H. Kwon, Carey-Ann D. Burnham, Gautam Dantas, Erik R. Dubberke, Cdc Prevention Epicenter Program

Open Access Publications

No abstract provided.


Domains Within Rbpa Serve Specific Functional Roles That Regulate The Expression Of Distinct Mycobacterial Gene Subsets, Jerome Prusa, Drake Jensen, Gustavo Santiago-Collazo, Steven S Pope, Ashley L Garner, Justin J Miller, Ana Ruiz Manzano, Eric A Galburt, Christina L Stallings Jan 2018

Domains Within Rbpa Serve Specific Functional Roles That Regulate The Expression Of Distinct Mycobacterial Gene Subsets, Jerome Prusa, Drake Jensen, Gustavo Santiago-Collazo, Steven S Pope, Ashley L Garner, Justin J Miller, Ana Ruiz Manzano, Eric A Galburt, Christina L Stallings

Open Access Publications

The RNA polymerase (RNAP) binding protein A (RbpA) contributes to the formation of stable RNAP-promoter open complexes (RP


Mycobacterium Tuberculosis Type Vii Secretion System Effectors Differentially Impact The Escrt Endomembrane Damage Response, Ekansh Mittal, Michael L. Skowyra, Grace Uwase, Emir Tinaztepe, Alka Mehra, Stefan Köster, Phyllis I. Hanson, Jennifer A. Philips Jan 2018

Mycobacterium Tuberculosis Type Vii Secretion System Effectors Differentially Impact The Escrt Endomembrane Damage Response, Ekansh Mittal, Michael L. Skowyra, Grace Uwase, Emir Tinaztepe, Alka Mehra, Stefan Köster, Phyllis I. Hanson, Jennifer A. Philips

Open Access Publications

No abstract provided.


Shed Eba-175 Mediates Red Blood Cell Clustering That Enhances Malaria Parasite Growth And Enables Immune Evasion, May M. Paing, Nichole D. Salinas, Yvonne Adams, Anna Oksman, Anja T.R. Jensen, Daniel E. Goldberg, Niraj H. Tolia Jan 2018

Shed Eba-175 Mediates Red Blood Cell Clustering That Enhances Malaria Parasite Growth And Enables Immune Evasion, May M. Paing, Nichole D. Salinas, Yvonne Adams, Anna Oksman, Anja T.R. Jensen, Daniel E. Goldberg, Niraj H. Tolia

Open Access Publications

No abstract provided.


Nitro-Fatty Acids Are Formed In Response To Virus Infection And Are Potent Inhibitors Of Sting Palmitoylation And Signaling, Cathrine A. Miner, Wei Qian, Jonathan J. Miner Jan 2018

Nitro-Fatty Acids Are Formed In Response To Virus Infection And Are Potent Inhibitors Of Sting Palmitoylation And Signaling, Cathrine A. Miner, Wei Qian, Jonathan J. Miner

Open Access Publications

No abstract provided.


Immunogenicity And Safety Of Three Consecutive Production Lots Of The Non Replicating Smallpox Vaccine Mva: A Randomised, Double Blind, Placebo Controlled Phase Iii Trial, Edgar Turner Overton, Steven J. Lawrence, Eva Wagner, Katrin Nopora, Siegfried Rosch, Philip Young, Darja Schnidt, Christian Kreusel, Sonja De Carli, Thomas P. Meyer, Heinz Weidenthaler, Nathaly Samy, Paul Chaplin Jan 2018

Immunogenicity And Safety Of Three Consecutive Production Lots Of The Non Replicating Smallpox Vaccine Mva: A Randomised, Double Blind, Placebo Controlled Phase Iii Trial, Edgar Turner Overton, Steven J. Lawrence, Eva Wagner, Katrin Nopora, Siegfried Rosch, Philip Young, Darja Schnidt, Christian Kreusel, Sonja De Carli, Thomas P. Meyer, Heinz Weidenthaler, Nathaly Samy, Paul Chaplin

Open Access Publications

No abstract provided.


An Assessment Of Inappropriate Antibiotic Use And Guideline Adherence For Uncomplicated Urinary Tract Infections, Michael J. Durkin, Matthew Keller, Anne M. Butler, Jennie H. Kwon, Erik R. Dubberke, Aaron C. Miller, Phillip M. Polgreen, Margaret A. Olsen Jan 2018

An Assessment Of Inappropriate Antibiotic Use And Guideline Adherence For Uncomplicated Urinary Tract Infections, Michael J. Durkin, Matthew Keller, Anne M. Butler, Jennie H. Kwon, Erik R. Dubberke, Aaron C. Miller, Phillip M. Polgreen, Margaret A. Olsen

Open Access Publications

No abstract provided.


Diagnostic Performance Of Multiplex Nucleic Acid Testing Of Bronchoalveolar Lavage And Bronchial Wash Specimens For Respiratory Viral Pathogens, Satish Munigala, Carey-Ann D. Burnham, Neil W. Anderson, Stephen Y. Liang, Steven J. Lawrence, David K. Warren Jan 2018

Diagnostic Performance Of Multiplex Nucleic Acid Testing Of Bronchoalveolar Lavage And Bronchial Wash Specimens For Respiratory Viral Pathogens, Satish Munigala, Carey-Ann D. Burnham, Neil W. Anderson, Stephen Y. Liang, Steven J. Lawrence, David K. Warren

Open Access Publications

No abstract provided.


Empiric Antibiotics For Sepsis, Sara A. Buckman, Isaiah R. Turnbull, John E. Mazuski Jan 2018

Empiric Antibiotics For Sepsis, Sara A. Buckman, Isaiah R. Turnbull, John E. Mazuski

Open Access Publications

No abstract provided.


Multicenter Evaluation Of The Xpert Mrsa Nxg Assay For Detection Of Methicillin-Resistant Staphylococcus Aureus In Nasal Swabs, Melanie L. Yarbrough, David K. Warren, Carey-Ann D. Burnham, Et Al Jan 2018

Multicenter Evaluation Of The Xpert Mrsa Nxg Assay For Detection Of Methicillin-Resistant Staphylococcus Aureus In Nasal Swabs, Melanie L. Yarbrough, David K. Warren, Carey-Ann D. Burnham, Et Al

Open Access Publications

No abstract provided.


Creation And Assessment Of A Clinical Predictive Calculator And Mortality Associated With Candida Krusei Bloodstream Infections, Ryan Kronen, Kevin Hsueh, Charlotte Lin, William G. Powderly, Andrej Spec Jan 2018

Creation And Assessment Of A Clinical Predictive Calculator And Mortality Associated With Candida Krusei Bloodstream Infections, Ryan Kronen, Kevin Hsueh, Charlotte Lin, William G. Powderly, Andrej Spec

Open Access Publications

No abstract provided.


Distinct Effects Of Type I And Iii Interferons On Enteric Viruses, Harshad Ingle, Stefan T. Peterson, Megan T. Baldridge Jan 2018

Distinct Effects Of Type I And Iii Interferons On Enteric Viruses, Harshad Ingle, Stefan T. Peterson, Megan T. Baldridge

Open Access Publications

No abstract provided.


Readmissions With Multidrug-Resistant Infection In Patients With Prior Multidrug Resistant Infection, Jason P. Burnham, Jennie H. Kwon, Margaret A. Olsen, Hilary M. Babcock, Marin H. Kollef Jan 2018

Readmissions With Multidrug-Resistant Infection In Patients With Prior Multidrug Resistant Infection, Jason P. Burnham, Jennie H. Kwon, Margaret A. Olsen, Hilary M. Babcock, Marin H. Kollef

Open Access Publications

No abstract provided.


Characteristics Of Pediatric Antimicrobial Stewardship Programs: Current Status Of The Sharing Antimicrobial Reports For Pediatric Stewardship (Sharps) Collaborative, Christopher Mcpherson, Brian R. Lee, Cindy Terrill, Adam L. Hersh, Jeffrey S. Gerber, Matthew P. Kronman, Jason G. Newland Jan 2018

Characteristics Of Pediatric Antimicrobial Stewardship Programs: Current Status Of The Sharing Antimicrobial Reports For Pediatric Stewardship (Sharps) Collaborative, Christopher Mcpherson, Brian R. Lee, Cindy Terrill, Adam L. Hersh, Jeffrey S. Gerber, Matthew P. Kronman, Jason G. Newland

Open Access Publications

No abstract provided.


Research Digest - December 2017, Division Of Public Health Sciences, Department Of Surgery, Washington University School Of Medicine In St. Louis Dec 2017

Research Digest - December 2017, Division Of Public Health Sciences, Department Of Surgery, Washington University School Of Medicine In St. Louis

Newsletters from the Division of Public Health Sciences

No abstract provided.


Research Digest - November 2017, Division Of Public Health Sciences, Department Of Surgery, Washington University School Of Medicine In St. Louis Nov 2017

Research Digest - November 2017, Division Of Public Health Sciences, Department Of Surgery, Washington University School Of Medicine In St. Louis

Newsletters from the Division of Public Health Sciences

No abstract provided.


Cerebrospinal Fluid And Blood Biomarkers For Neurodegenerative Dementias: An Update Of The Consensus Of The Task Force On Biological Markers In Psychiatry Of The World Federation Of Societies Of Biological Psychiatry, Piotr Lewczuk, Anne M. Fagan, Brian A. Gordon, Et Al Oct 2017

Cerebrospinal Fluid And Blood Biomarkers For Neurodegenerative Dementias: An Update Of The Consensus Of The Task Force On Biological Markers In Psychiatry Of The World Federation Of Societies Of Biological Psychiatry, Piotr Lewczuk, Anne M. Fagan, Brian A. Gordon, Et Al

Open Access Publications

No abstract provided.


Interleukin-17 Limits Hypoxia-Inducible Factor 1Α And Development Of Hypoxic Granulomas During Tuberculosis, Racquel Domingo-Gonzalez, Shibali Das, Kristin L. Griffiths, Mushtaq Ahmed, Monika Bambouskova, Suhas Gondi, Noor Al-Hammadi, Reid Townsend, Maxim N. Artyomov, Shabaana A. Khader, Et Al. Oct 2017

Interleukin-17 Limits Hypoxia-Inducible Factor 1Α And Development Of Hypoxic Granulomas During Tuberculosis, Racquel Domingo-Gonzalez, Shibali Das, Kristin L. Griffiths, Mushtaq Ahmed, Monika Bambouskova, Suhas Gondi, Noor Al-Hammadi, Reid Townsend, Maxim N. Artyomov, Shabaana A. Khader, Et Al.

Open Access Publications

Mycobacterium tuberculosis (Mtb) is a global health threat, compounded by the emergence of drug-resistant strains. A hallmark of pulmonary tuberculosis (TB) is the formation of hypoxic necrotic granulomas, which upon disintegration, release infectious Mtb. Furthermore, hypoxic necrotic granulomas are associated with increased disease severity and provide a niche for drug-resistant Mtb. However, the host immune responses that promote the development of hypoxic TB granulomas are not well described. Using a necrotic Mtb mouse model, we show that loss of Mtb virulence factors, such as phenolic glycolipids, decreases the production of the proinflammatory cytokine IL-17 (also referred to as IL-17A). IL-17 …