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Washington University School of Medicine

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Moderately Neutralizing Epitopes In Nonfunctional Regions Dominate The Antibody Response To Plasmodium Falciparum Eba-140, Nichole D. Salinas, May M. Paing, Jagat Adhikari, Michael L. Gross, Niraj Tolia Jan 2019

Moderately Neutralizing Epitopes In Nonfunctional Regions Dominate The Antibody Response To Plasmodium Falciparum Eba-140, Nichole D. Salinas, May M. Paing, Jagat Adhikari, Michael L. Gross, Niraj Tolia

Open Access Publications

No abstract provided.


The Natural Cytotoxicity Receptors In Health And Disease, Alexander David Barrow, Claudia Jane Martin, Marco Colonna Jan 2019

The Natural Cytotoxicity Receptors In Health And Disease, Alexander David Barrow, Claudia Jane Martin, Marco Colonna

Open Access Publications

No abstract provided.


Combining Procalcitonin With The Qsofa And Sepsis Mortality Prediction, Hua Yu, Lu Nie, Aibo Liu, Kuihai Wu, Yenh-Chen Hsein, Debra W. Yen, Meng-Tse G. Lee, Chien-Chang Lee Jan 2019

Combining Procalcitonin With The Qsofa And Sepsis Mortality Prediction, Hua Yu, Lu Nie, Aibo Liu, Kuihai Wu, Yenh-Chen Hsein, Debra W. Yen, Meng-Tse G. Lee, Chien-Chang Lee

Open Access Publications

No abstract provided.


2019 Update Of The Wses Guidelines For Management Of Clostridioides (Clostridium) Difficile Infection In Surgical Patients, John E. Mazuski, Et Al Jan 2019

2019 Update Of The Wses Guidelines For Management Of Clostridioides (Clostridium) Difficile Infection In Surgical Patients, John E. Mazuski, Et Al

Open Access Publications

No abstract provided.


An Overview Of Mechanical Circulatory Support In Single-Ventricle Patients, Jacob R Miller, Timothy S Lancaster, Connor Callahan, Aaron M Abarbanell, Pirooz Eghtesady Jan 2019

An Overview Of Mechanical Circulatory Support In Single-Ventricle Patients, Jacob R Miller, Timothy S Lancaster, Connor Callahan, Aaron M Abarbanell, Pirooz Eghtesady

Open Access Publications

The population of people with a single-ventricle is continually increasing due to improvements across the spectrum of medical care. Unfortunately, a proportion of these patients will develop heart failure. Often, for these patients, mechanical circulatory support (MCS) represents the only available treatment option. While single-ventricle patients currently represent a small proportion of the total number of patients who receive MCS, as the single-ventricle patient population increases, this number will increase as well. Outcomes for these complex single-ventricle patients who require MCS has begun to be evaluated. When considering the entire population, survival to hospital discharge is 30-50%, though this must …


Comparative Analysis Of Roseoloviruses In Humans, Pigs, Mice, And Other Species, Joachim Denner, Tarin M Bigley, Tuan L Phan, Cosima Zimmermann, Xiaofeng Zhou, Benedikt B Kaufer Jan 2019

Comparative Analysis Of Roseoloviruses In Humans, Pigs, Mice, And Other Species, Joachim Denner, Tarin M Bigley, Tuan L Phan, Cosima Zimmermann, Xiaofeng Zhou, Benedikt B Kaufer

Open Access Publications

Viruses of the genus


The Children's Respiratory And Environmental Workgroup (Crew) Birth Cohort Consortium: Design, Methods, And Study Population, James E. Gern, Leonard B. Bacharier, Et Al Jan 2019

The Children's Respiratory And Environmental Workgroup (Crew) Birth Cohort Consortium: Design, Methods, And Study Population, James E. Gern, Leonard B. Bacharier, Et Al

Open Access Publications

No abstract provided.


Clinical Impact Of Revised Cefepime Breakpoint In Patients With Enterobacteriaceae Bacteremia, Kap Sum Foong, Abigail L. Carlson, Munigala Satish, Carey-Ann D. Burnham, David K. Warren Jan 2019

Clinical Impact Of Revised Cefepime Breakpoint In Patients With Enterobacteriaceae Bacteremia, Kap Sum Foong, Abigail L. Carlson, Munigala Satish, Carey-Ann D. Burnham, David K. Warren

Open Access Publications

No abstract provided.


Seasonal Changes In The Prevalence Of Antibiotic-Susceptible Acinetobacter Calcoaceticus-Baumannii Complex Isolates Result In Increased Multidrug Resistance Rates During Winter Months, Jason P. Burnham, Mario F. Feldman, Juan J. Calix Jan 2019

Seasonal Changes In The Prevalence Of Antibiotic-Susceptible Acinetobacter Calcoaceticus-Baumannii Complex Isolates Result In Increased Multidrug Resistance Rates During Winter Months, Jason P. Burnham, Mario F. Feldman, Juan J. Calix

Open Access Publications

No abstract provided.


Variation In The Delivery Of Inpatient Orthopaedic Care To Medicaid Beneficiaries Within A Single Metropolitan Region, Christopher J. Dy, Andrew D. Tipping, Katelin B. Nickel, Winston Jiang, Regis J. O'Keefe, Margaret A. Olsen Jan 2019

Variation In The Delivery Of Inpatient Orthopaedic Care To Medicaid Beneficiaries Within A Single Metropolitan Region, Christopher J. Dy, Andrew D. Tipping, Katelin B. Nickel, Winston Jiang, Regis J. O'Keefe, Margaret A. Olsen

Open Access Publications

No abstract provided.


Cluster Analysis To Define Distinct Clinical Phenotypes Among Septic Patients With Bloodstream Infections, Maria Cristina Vazquez Guilamet, Michael Bernauer, Scott T. Micek, Marin H. Kollef Jan 2019

Cluster Analysis To Define Distinct Clinical Phenotypes Among Septic Patients With Bloodstream Infections, Maria Cristina Vazquez Guilamet, Michael Bernauer, Scott T. Micek, Marin H. Kollef

Open Access Publications

No abstract provided.


A Promising Bioconjugate Vaccine Against Hypervirulent Klebsiella Pneumoniae, Mario F. Feldman, Anne E. Mayer Bridwell, Nichollas E. Scott, Evgeny Vinogradov, Samuel R. Mckee, Sthefany M. Chavez, Joy Twentyman, Christina L. Stallings, David A. Rosen, Christian M. Harding Jan 2019

A Promising Bioconjugate Vaccine Against Hypervirulent Klebsiella Pneumoniae, Mario F. Feldman, Anne E. Mayer Bridwell, Nichollas E. Scott, Evgeny Vinogradov, Samuel R. Mckee, Sthefany M. Chavez, Joy Twentyman, Christina L. Stallings, David A. Rosen, Christian M. Harding

Open Access Publications

No abstract provided.


Uterine Natural Killer Cells, Dorothy K. Sojka, Liping Yang, Wayne M. Yokoyama Jan 2019

Uterine Natural Killer Cells, Dorothy K. Sojka, Liping Yang, Wayne M. Yokoyama

Open Access Publications

No abstract provided.


The Role Of Fecal Microbiota Transplantation In Reducing Intestinal Colonization With Antibiotic-Resistant Organisms: The Current Landscape And Future Directions, Michael H. Woodworth, Mary K. Hayden, Vincent B. Young, Jennie H. Kwon Jan 2019

The Role Of Fecal Microbiota Transplantation In Reducing Intestinal Colonization With Antibiotic-Resistant Organisms: The Current Landscape And Future Directions, Michael H. Woodworth, Mary K. Hayden, Vincent B. Young, Jennie H. Kwon

Open Access Publications

No abstract provided.


The Widely Used Antimicrobial Triclosan Induces High Levels Of Antibiotic Tolerance In Vitro And Reduces Antibiotic Efficacy Up To 100-Fold In Vivo, Corey Westfall, Ana Lidia Flores-Mireles, John Isaac Robinson, Aaron J.L. Lynch, Scott Hultgren, Jeffrey P. Henderson, Petra Anne Levin Jan 2019

The Widely Used Antimicrobial Triclosan Induces High Levels Of Antibiotic Tolerance In Vitro And Reduces Antibiotic Efficacy Up To 100-Fold In Vivo, Corey Westfall, Ana Lidia Flores-Mireles, John Isaac Robinson, Aaron J.L. Lynch, Scott Hultgren, Jeffrey P. Henderson, Petra Anne Levin

Open Access Publications

No abstract provided.


Incidence Of Acute Kidney Injury In Critically Ill Patients Receiving Vancomycin With Concomitant Piperacillin-Tazobactam, Cefepime, Or Meropenem, Adam M. Blevins, Jennifer N. Lashinsky, Craig Mccammon, Marin Kollef, Scott Micek, Paul Juang Jan 2019

Incidence Of Acute Kidney Injury In Critically Ill Patients Receiving Vancomycin With Concomitant Piperacillin-Tazobactam, Cefepime, Or Meropenem, Adam M. Blevins, Jennifer N. Lashinsky, Craig Mccammon, Marin Kollef, Scott Micek, Paul Juang

Open Access Publications

No abstract provided.


Going Beyond The Individual: How State-Level Characteristics Relate To Hpv Vaccine Rates In The United States, Melissa Franco, Stephanie Mazzucca, Margaret Padek, Ross C. Brownson Jan 2019

Going Beyond The Individual: How State-Level Characteristics Relate To Hpv Vaccine Rates In The United States, Melissa Franco, Stephanie Mazzucca, Margaret Padek, Ross C. Brownson

Open Access Publications

No abstract provided.


Pigment Visibility On Rectal Swabs Used To Detect Enteropathogens: A Prospective Cohort Study, Jianling Xie, Gillian A.M. Tarr, Samina Ali, Linda Chui, Xiao-Li Pang, Bonita E. Lee, Otto G. Vanderkooi, Phillip I. Tarr, Ran Zhuo, Brendon Parsons, Byron M. Berenger, Kelly Kim, Stephen B. Freedman, Alberta Provincial Pediatric Enteric Infection Team (Appetite) And Pediatric Emergency Research Canada (Perc) Jan 2019

Pigment Visibility On Rectal Swabs Used To Detect Enteropathogens: A Prospective Cohort Study, Jianling Xie, Gillian A.M. Tarr, Samina Ali, Linda Chui, Xiao-Li Pang, Bonita E. Lee, Otto G. Vanderkooi, Phillip I. Tarr, Ran Zhuo, Brendon Parsons, Byron M. Berenger, Kelly Kim, Stephen B. Freedman, Alberta Provincial Pediatric Enteric Infection Team (Appetite) And Pediatric Emergency Research Canada (Perc)

Open Access Publications

No abstract provided.


Effect Of Changing Urine Testing Orderables And Clinician Order Sets On Inpatient Urine Culture Testing: Analysis From A Large Academic Medical Center, Satish Munigala, Rebecca Rojek, Helen Wood, Melanie L. Yarbrough, Ronald R. Jackups, Carey-Ann D. Burnham, David K. Warren Jan 2019

Effect Of Changing Urine Testing Orderables And Clinician Order Sets On Inpatient Urine Culture Testing: Analysis From A Large Academic Medical Center, Satish Munigala, Rebecca Rojek, Helen Wood, Melanie L. Yarbrough, Ronald R. Jackups, Carey-Ann D. Burnham, David K. Warren

Open Access Publications

No abstract provided.


Outcomes Of Haploidentical Vs Matched Sibling Transplantation For Acute Myeloid Leukemia In First Complete Remission, Keith Stockerl-Goldstein, Et Al. Jan 2019

Outcomes Of Haploidentical Vs Matched Sibling Transplantation For Acute Myeloid Leukemia In First Complete Remission, Keith Stockerl-Goldstein, Et Al.

Open Access Publications

No abstract provided.


(P)Ppgpp And Cody Promote Enterococcus Faecalis Virulence In A Murine Model Of Catheter-Associated Urinary Tract Infection, C. Colomer-Winter, A. L. Flores-Mireles, S. Kundra, S. J. Hultgren, J. A. Lemos Jan 2019

(P)Ppgpp And Cody Promote Enterococcus Faecalis Virulence In A Murine Model Of Catheter-Associated Urinary Tract Infection, C. Colomer-Winter, A. L. Flores-Mireles, S. Kundra, S. J. Hultgren, J. A. Lemos

Open Access Publications

No abstract provided.


De Novo Assembly Of The Brugia Malayi Genome Using Long Reads From A Single Minion Flowcell, Joseph R. Fauver, John Martin, Gary J. Weil, Makedonka Mitreva, Peter U. Fischer Jan 2019

De Novo Assembly Of The Brugia Malayi Genome Using Long Reads From A Single Minion Flowcell, Joseph R. Fauver, John Martin, Gary J. Weil, Makedonka Mitreva, Peter U. Fischer

Open Access Publications

No abstract provided.


Reported Variability In Healthcare Facility Policies Regarding Healthcare Personnel Working While Experiencing Influenza-Like Illnesses: An Emerging Infections Network Survey, Hilary M Babcock, Susan E Beekmann, Satish K Pillai, Scott Santibanez, Leslie Lee, David T Kuhar, Angela P Campbell, Anita Patel, Philip M Polgreen Jan 2019

Reported Variability In Healthcare Facility Policies Regarding Healthcare Personnel Working While Experiencing Influenza-Like Illnesses: An Emerging Infections Network Survey, Hilary M Babcock, Susan E Beekmann, Satish K Pillai, Scott Santibanez, Leslie Lee, David T Kuhar, Angela P Campbell, Anita Patel, Philip M Polgreen

Open Access Publications

BACKGROUND: Presenteeism, or working while ill, by healthcare personnel (HCP) experiencing influenza-like illness (ILI) puts patients and coworkers at risk. However, hospital policies and practices may not consistently facilitate HCP staying home when ill.

OBJECTIVE AND METHODS: We conducted a mixed-methods survey in March 2018 of Emerging Infections Network infectious diseases physicians, describing institutional experiences with and policies for HCP working with ILI.

RESULTS: Of 715 physicians, 367 (51%) responded. Of 367, 135 (37%) were unaware of institutional policies. Of the remaining 232 respondents, 206 (89%) reported institutional policies regarding work restrictions for HCP with influenza or ILI, but only …


Clostridium Difficile Infection Increases Acute And Chronic Morbidity And Mortality, Margaret A. Olsen, Dustin Stwalley, Clarisse Demont, Erik R. Dubberke Jan 2019

Clostridium Difficile Infection Increases Acute And Chronic Morbidity And Mortality, Margaret A. Olsen, Dustin Stwalley, Clarisse Demont, Erik R. Dubberke

Open Access Publications

No abstract provided.


Whole-Genome Sequencing Of Klebsiella Pneumoniae Isolates To Track Strain Progression In A Single Patient With Recurrent Urinary Tract Infection, Kristine M. Wylie, Todd N. Wylie, Patrick J. Minx, David A. Rosen Jan 2019

Whole-Genome Sequencing Of Klebsiella Pneumoniae Isolates To Track Strain Progression In A Single Patient With Recurrent Urinary Tract Infection, Kristine M. Wylie, Todd N. Wylie, Patrick J. Minx, David A. Rosen

Open Access Publications

No abstract provided.


The Impact Of The Graft-Versus-Leukemia Effect On Survival In Acute Lymphoblastic Leukemia, Moshe Yeshurun, Geoffrey Uy, Et Al Jan 2019

The Impact Of The Graft-Versus-Leukemia Effect On Survival In Acute Lymphoblastic Leukemia, Moshe Yeshurun, Geoffrey Uy, Et Al

Open Access Publications

No abstract provided.


The Detection Of Bacteria And Matrix Proteins On Clinically Benign And Pathologic Implants, Jennifer N. Walker, Chloe L. Pinkner, Jerome S. Pinkner, Scott J. Hultgren, Terence M. Myckatyn Jan 2019

The Detection Of Bacteria And Matrix Proteins On Clinically Benign And Pathologic Implants, Jennifer N. Walker, Chloe L. Pinkner, Jerome S. Pinkner, Scott J. Hultgren, Terence M. Myckatyn

Open Access Publications

No abstract provided.


A Culture-Independent Analysis Of The Microbiota Of Female Interstitial Cystitis/Bladder Pain Syndrome Participants In The Mapp Research Network, J. C. Nickel, Alisa J. Stephens-Shields, J. R. Landis, Chris Mullins, Adrie Van Bokhoven, M. S. Lucia, Jeffrey P. Henderson, Bhaswati Sen, Jaroslaw E. Krol, Garth D. Ehrlich, The Mapp Research Network Jan 2019

A Culture-Independent Analysis Of The Microbiota Of Female Interstitial Cystitis/Bladder Pain Syndrome Participants In The Mapp Research Network, J. C. Nickel, Alisa J. Stephens-Shields, J. R. Landis, Chris Mullins, Adrie Van Bokhoven, M. S. Lucia, Jeffrey P. Henderson, Bhaswati Sen, Jaroslaw E. Krol, Garth D. Ehrlich, The Mapp Research Network

Open Access Publications

No abstract provided.


Patient Engagement And Cost Savings Achieved By Automated Telemonitoring Systems Designed To Prevent And Identify Surgical Site Infections After Joint Replacement, Alexander T. Yahanda, Nikolas E. Marino, John Barron, Angela Concepcion, Theresa St. John, Keyin Lu, Christopher Chermside-Scabbo, Bola Aladegbami, Will Ross, John Clohisy, John P. Kirby Jan 2019

Patient Engagement And Cost Savings Achieved By Automated Telemonitoring Systems Designed To Prevent And Identify Surgical Site Infections After Joint Replacement, Alexander T. Yahanda, Nikolas E. Marino, John Barron, Angela Concepcion, Theresa St. John, Keyin Lu, Christopher Chermside-Scabbo, Bola Aladegbami, Will Ross, John Clohisy, John P. Kirby

Open Access Publications

No abstract provided.


Zbtb32 Restrains Antibody Responses To Murine Cytomegalovirus Infections, But Not Other Repetitive Challenges, Arijita Jash, You W. Zhou, Diana K. Gerardo, Tyler J. Ripperger, Bijal A. Parikh, Sytse Piersma, Deepa R. Jamwal, Pawel R. Kiela, Adrianus C. M. Boon, Wayne M. Yokoyama, Chyi S. Hsieh, Deepta Bhattacharya Jan 2019

Zbtb32 Restrains Antibody Responses To Murine Cytomegalovirus Infections, But Not Other Repetitive Challenges, Arijita Jash, You W. Zhou, Diana K. Gerardo, Tyler J. Ripperger, Bijal A. Parikh, Sytse Piersma, Deepa R. Jamwal, Pawel R. Kiela, Adrianus C. M. Boon, Wayne M. Yokoyama, Chyi S. Hsieh, Deepta Bhattacharya

Open Access Publications

No abstract provided.