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Washington University School of Medicine

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Articles 14191 - 14220 of 20421

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Bjc Today Mar 2011

Bjc Today

BJC Today

No abstract provided.


Are Dropped Osteoarticular Bone Fragments Safely Reimplantable In Vivo?, Benjamin Bruce, Shahin Sheibani-Rad, Deborah Appleyard, Ryan P. Calfee, Steven E. Reinert, Kimberle C. Chapin, Christopher W. Digiovanni Mar 2011

Are Dropped Osteoarticular Bone Fragments Safely Reimplantable In Vivo?, Benjamin Bruce, Shahin Sheibani-Rad, Deborah Appleyard, Ryan P. Calfee, Steven E. Reinert, Kimberle C. Chapin, Christopher W. Digiovanni

Open Access Publications

No abstract provided.


Igh Gene Rearrangements As Plasma Biomarkers In Non- Hodgkin's Lymphoma Patients, Jian He, Jian Wu, Yuchen Jiao, Nina Wagner-Johnston, Richard F. Ambinder, Luis A. Diaz, Kenneth W. Kinzler, Bert Vogelstein, Nickolas Papadopoulos Mar 2011

Igh Gene Rearrangements As Plasma Biomarkers In Non- Hodgkin's Lymphoma Patients, Jian He, Jian Wu, Yuchen Jiao, Nina Wagner-Johnston, Richard F. Ambinder, Luis A. Diaz, Kenneth W. Kinzler, Bert Vogelstein, Nickolas Papadopoulos

Open Access Publications

New biomarkers with improved accuracy could be helpful for monitoring disease in patients with Non-Hodgkin's lymphomas (NHL). Towards this end, we have explored the feasibility of identifying the sequence of rearranged IgH genes using next-generation sequencing, then using PCR to detect specific rearranged DNA fragments in patients' plasma. By capturing and sequencing the IgH genomic regions (IgCap), we were able to detect and precisely determine the sequence of rearranged IgH loci in the tumors of three NHL patients. Moreover, circulating rearranged DNA fragments could be identified in the plasma of all three patients. Even in cases wherein tumor biopsies were …


Scapular And Humeral Movement Patterns Of People With Stroke During Range-Of-Motion Exercises, Dustin D. Hardwick, Catherine E. Lang Mar 2011

Scapular And Humeral Movement Patterns Of People With Stroke During Range-Of-Motion Exercises, Dustin D. Hardwick, Catherine E. Lang

Physical Therapy Faculty Publications

No abstract provided.


Bjc Today Feb 2011

Bjc Today

BJC Today

No abstract provided.


Effect Of Short-Duration Low-Magnitude Cyclic Loading Versus Immobilization On Tendon-Bone Healing After Acl Reconstruction In A Rat Model, Robert H. Brophy, David Kovacevic, Carl W. Imhauser, Mark Stasiak, Asheesh Bedi, Alice J.S. Fox, Xiang-Hua Deng, Scott A. Rodeo Feb 2011

Effect Of Short-Duration Low-Magnitude Cyclic Loading Versus Immobilization On Tendon-Bone Healing After Acl Reconstruction In A Rat Model, Robert H. Brophy, David Kovacevic, Carl W. Imhauser, Mark Stasiak, Asheesh Bedi, Alice J.S. Fox, Xiang-Hua Deng, Scott A. Rodeo

Open Access Publications

No abstract provided.


Nonuniform High-Gamma (60-500 Hz) Power Changes Dissociate Cognitive Task And Anatomy In Human Cortex, Charles M. Gaona, Mohit Sharma, Zachary V. Freudenburg, Jonathan D. Breshears, David T. Bundy, Jarod Roland, Dennis L. Barbour, Gerwin Schalk, Eric C. Leuthardt Feb 2011

Nonuniform High-Gamma (60-500 Hz) Power Changes Dissociate Cognitive Task And Anatomy In Human Cortex, Charles M. Gaona, Mohit Sharma, Zachary V. Freudenburg, Jonathan D. Breshears, David T. Bundy, Jarod Roland, Dennis L. Barbour, Gerwin Schalk, Eric C. Leuthardt

Open Access Publications

High-gamma-band (>60 Hz) power changes in cortical electrophysiology are a reliable indicator of focal, event-related cortical activity. Despite discoveries of oscillatory subthreshold and synchronous suprathreshold activity at the cellular level, there is an increasingly popular view that high-gamma-band amplitude changes recorded from cellular ensembles are the result of asynchronous firing activity that yields wideband and uniform power increases. Others have demonstrated independence of power changes in the low- and high-gamma bands, but to date, no studies have shown evidence of any such independence above 60 Hz. Based on nonuniformities in time-frequency analyses of electrocorticographic (ECoG) signals, we hypothesized that …


Bjc Today Feb 2011

Bjc Today

BJC Today

No abstract provided.


Podokinetic Stimulation Causes Shifts In Perception Of Straight Ahead, John T. Scott, Corey A. Lohnes, Fay B. Horak, Gammon M. Earhart Feb 2011

Podokinetic Stimulation Causes Shifts In Perception Of Straight Ahead, John T. Scott, Corey A. Lohnes, Fay B. Horak, Gammon M. Earhart

Physical Therapy Faculty Publications

No abstract provided.


Bjc Today Jan 2011

Bjc Today

BJC Today

No abstract provided.


Calcium-Independent Inhibitory G-Protein Signaling Induces Persistent Presynaptic Muting Of Hippocampal Synapses, Devon C. Crawford, Chun Yun Chang, Krzysztof L. Hyrc, Steven Mennerick Jan 2011

Calcium-Independent Inhibitory G-Protein Signaling Induces Persistent Presynaptic Muting Of Hippocampal Synapses, Devon C. Crawford, Chun Yun Chang, Krzysztof L. Hyrc, Steven Mennerick

Open Access Publications

Adaptive forms of synaptic plasticity that reduce excitatory synaptic transmission in response to prolonged increases in neuronal activity may prevent runaway positive feedback in neuronal circuits. In hippocampal neurons, for example, glutamatergic presynaptic terminals are selectively silenced, creating "mute" synapses, after periods of increased neuronal activity or sustained depolarization. Previous work suggests that cAMP-dependent and proteasome-dependent mechanisms participate in silencing induction by depolarization, but upstream activators are unknown. We, therefore, tested the role of calcium and G-protein signaling in silencing induction in cultured hippocampal neurons. We found that silencing induction by depolarization was not dependent on rises in intracellular calcium, …


Bjc Today Jan 2011

Bjc Today

BJC Today

No abstract provided.


In Vitro And In Vivo Evaluation Of 64cu-Radiolabeled Kccysl Peptides For Targeting Epidermal Growth Factor Receptor-2 In Breast Carcinomas, Senthil R. Kumar, Fabio A. Gallazzi, Riccardo Ferdani, Carolyn J. Anderson, Thomas P. Quinn, Susan L. Deutscher Jan 2011

In Vitro And In Vivo Evaluation Of 64cu-Radiolabeled Kccysl Peptides For Targeting Epidermal Growth Factor Receptor-2 In Breast Carcinomas, Senthil R. Kumar, Fabio A. Gallazzi, Riccardo Ferdani, Carolyn J. Anderson, Thomas P. Quinn, Susan L. Deutscher

Open Access Publications

No abstract provided.


Pacs Bulletin 2011-2012, Program In Audiology And Communication Sciences Jan 2011

Pacs Bulletin 2011-2012, Program In Audiology And Communication Sciences

PACS News

No abstract provided.


Institute Of Clinical And Translational Sciences News, Vol. 3, Issue 4 Jan 2011

Institute Of Clinical And Translational Sciences News, Vol. 3, Issue 4

ICTS Newsletters

No abstract provided.


Institute Of Clinical And Translational Sciences News, Vol. 4, Issue 3 Jan 2011

Institute Of Clinical And Translational Sciences News, Vol. 4, Issue 3

ICTS Newsletters

No abstract provided.


Effect Of Stimulus Intensity On Cortical Potentials In Cochlear Implant Recipients, Laura Jean Czarniak Jan 2011

Effect Of Stimulus Intensity On Cortical Potentials In Cochlear Implant Recipients, Laura Jean Czarniak

Independent Studies and Capstones

Cortical auditory evoked potentials were recorded in cochlear implant recipients and in individuals with normal hearing using a speech stimulus. Responses were acquired over two test sessions to investigate between group differences and test repeatability. Results indicate significant differences in N1-P2 latency and amplitude measures between cochlear implant recipients and individuals with normal hearing.


Changes In Events Alter How People Remember Recent Information, Khena M. Swallow, Deanna M. Barch, Denise Head, Corey J. Maley, Derek Holder, Jeffrey M. Zacks Jan 2011

Changes In Events Alter How People Remember Recent Information, Khena M. Swallow, Deanna M. Barch, Denise Head, Corey J. Maley, Derek Holder, Jeffrey M. Zacks

Open Access Publications

No abstract provided.


Reading Comprehension And Oral Reading Fluency Of Deaf Children With Cochlear Implants, Kasie Gueringer Jan 2011

Reading Comprehension And Oral Reading Fluency Of Deaf Children With Cochlear Implants, Kasie Gueringer

Independent Studies and Capstones

This study investigates whether deaf children with cochlear implants have oral reading fluency scores comparable to reading-age matched hearing peers. It also examines the reading comprehension skills of deaf children with cochlear implants.


Cellular Signals Of Cisplatin Ototoxicity, Lindsey M. Yarnell Jan 2011

Cellular Signals Of Cisplatin Ototoxicity, Lindsey M. Yarnell

Independent Studies and Capstones

Three separate theories of inhibiting cisplatin-induced apoptosis were investigated utilizing different cellular mechanisms. Specifically, the copper transport cycle, TRPV1, and the JNK pathway were inhibited and immunohistochemistry was performed to determine levels of apoptosis. All three resulted in statistically significant effects; increasing CuSO4 levels resulted in increased apoptosis, and inhibiting TRPV1


Multiplexed Immunoassay Panel Identifies Novel Csf Biomarkers For Alzheimer's Disease Diagnosis And Prognosis, Rebecca Craig-Shapiro, Max Kuhn, Chengjie Xiong, Eve H. Pickering, Jingxia Liu, Thomas P. Misko, Richard J. Perrin, Kelly R. Bales, Holly Soares, Anne M. Fagan, David H. Holtzman Jan 2011

Multiplexed Immunoassay Panel Identifies Novel Csf Biomarkers For Alzheimer's Disease Diagnosis And Prognosis, Rebecca Craig-Shapiro, Max Kuhn, Chengjie Xiong, Eve H. Pickering, Jingxia Liu, Thomas P. Misko, Richard J. Perrin, Kelly R. Bales, Holly Soares, Anne M. Fagan, David H. Holtzman

ICTS Faculty Publications

No abstract provided.


Identification And Validation Of Novel Cerebrospinal Fluid Biomarkers For Staging Early Alzheimer's Disease, Richard J. Perrin, Rebecca Craig-Shapiro, James P. Malone, Aarti R. Shah, Petra Gilmore, Alan E. Davis, Catherine M. Roe, Elaine R. Peskind, Ge Li, Douglas R. Galasko, Christopher M. Clark, Joseph F. Quinn, Jeffrey A. Kaye, John C. Morris, David H. Holtzman, Anne M. Fagan Jan 2011

Identification And Validation Of Novel Cerebrospinal Fluid Biomarkers For Staging Early Alzheimer's Disease, Richard J. Perrin, Rebecca Craig-Shapiro, James P. Malone, Aarti R. Shah, Petra Gilmore, Alan E. Davis, Catherine M. Roe, Elaine R. Peskind, Ge Li, Douglas R. Galasko, Christopher M. Clark, Joseph F. Quinn, Jeffrey A. Kaye, John C. Morris, David H. Holtzman, Anne M. Fagan

ICTS Faculty Publications

No abstract provided.


Vacuolization Of Mucolipidosis Type Ii Mouse Exocrine Gland Cells Represents Accumulation Of Autolysosomes, Marielle Boonen, Eline Van Meel, Viola Oorschot, Judith Klumperman, Stuart Kornfeld Jan 2011

Vacuolization Of Mucolipidosis Type Ii Mouse Exocrine Gland Cells Represents Accumulation Of Autolysosomes, Marielle Boonen, Eline Van Meel, Viola Oorschot, Judith Klumperman, Stuart Kornfeld

Open Access Publications

No abstract provided.


Fatty-Acid Binding Proteins Modulate Sleep And Enhance Long-Term Memory Consolidation In Drosophila, Jason R. Gerstner, William M. Vanderheyden, Paul J. Shaw, Charles F. Landry, Jerry C. P. Yin Jan 2011

Fatty-Acid Binding Proteins Modulate Sleep And Enhance Long-Term Memory Consolidation In Drosophila, Jason R. Gerstner, William M. Vanderheyden, Paul J. Shaw, Charles F. Landry, Jerry C. P. Yin

Open Access Publications

No abstract provided.


Diffusion Of Mmps On The Surface Of Collagen Fibrils: The Mobile Cell Surface - Collagen Substratum Interface, Ivan E. Collier, Wesley Legant, Barry Marmer, Olga Lubman, Saveez Saffarian, Tetsuro Wakatsuki, Elliot Elson, Gregory I. Goldberg Jan 2011

Diffusion Of Mmps On The Surface Of Collagen Fibrils: The Mobile Cell Surface - Collagen Substratum Interface, Ivan E. Collier, Wesley Legant, Barry Marmer, Olga Lubman, Saveez Saffarian, Tetsuro Wakatsuki, Elliot Elson, Gregory I. Goldberg

Open Access Publications

No abstract provided.


Representation Of Vestibular And Visual Cues To Self-Motion In Ventral Intraparietal Cortex, Aihua Chen, Gregory C. Deangelis, Dora E. Angelaki Jan 2011

Representation Of Vestibular And Visual Cues To Self-Motion In Ventral Intraparietal Cortex, Aihua Chen, Gregory C. Deangelis, Dora E. Angelaki

Open Access Publications

No abstract provided.


Evaluation Of Different Signal Processing Options In Unilateral And Bilateral Cochlear Freedom Implant Recipients Using R-Space Background Noise, Alison M. Brockmeyer, Lisa G. Potts Jan 2011

Evaluation Of Different Signal Processing Options In Unilateral And Bilateral Cochlear Freedom Implant Recipients Using R-Space Background Noise, Alison M. Brockmeyer, Lisa G. Potts

Publications

No abstract provided.


Institute Of Clinical And Translational Sciences News, Vol. 4, Issue 1 Jan 2011

Institute Of Clinical And Translational Sciences News, Vol. 4, Issue 1

ICTS Newsletters

No abstract provided.


2011 Device Advice From The Fda: Irb Case Study Questions, Human Research Protection Office, Washington University School Of Medicine In St. Louis Jan 2011

2011 Device Advice From The Fda: Irb Case Study Questions, Human Research Protection Office, Washington University School Of Medicine In St. Louis

2011 Device Advice from the FDA

No abstract provided.


Poster Committee, Human Research Protection Office, Washington University School Of Medicine In St. Louis Jan 2011

Poster Committee, Human Research Protection Office, Washington University School Of Medicine In St. Louis

2011 St. Louis OHRP National Research Forum and Community-Engaged Research Conference

No abstract provided.