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“I Know What Nothing Means”: Nostalgia, Hope, And The Postmodern Search For The Sublime, Kathryn L. Donati Jan 2024

“I Know What Nothing Means”: Nostalgia, Hope, And The Postmodern Search For The Sublime, Kathryn L. Donati

Theses and Dissertations

Amid simultaneous crises of self, nation, digital citizenship, global health, climate change, and socio-political polarization, to name but a few of the catastrophes that seem to define life in the global West in the twenty-first century, where do we find hope? Do we find it at all? Is there any hope to be found? These are the questions that serve as the genesis for this undertaking in which I locate the origin of these crises far before the events of the 2016 and 2020 elections, far before even the panic of Y2K. I begin my examination of hope in contemporary …


Validation Of A Screening Tool For Sleep Apnea In Children, Brandon Khor Jan 2024

Validation Of A Screening Tool For Sleep Apnea In Children, Brandon Khor

Theses and Dissertations

Objective: The aims of this study were to (1) determine the ability of a pediatric obstructive sleep apnea (POSA) questionnaire to identify high-risk patients through confirmation with an at-home sleep apnea test (HSAT) and (2) to evaluate the correlation between high-risk patients as identified by the questionnaire (PM-STOP-Bang) and an already validated POSA screening tool.

Methods: Orthodontic patients aged 12-17 who met the inclusion criteria were consecutively enrolled in the study (n=16). At the initial orthodontic appointment, the clinician filled out the PM-STOP-Bang questionnaire. Subsequently, participants were invited to complete a one-night HSAT (WatchPat, WP-Itamar-Medical, Caesarea, Israel), which recorded diagnostic …


A Precision-Controlled Investigation Into The Fundamentals Which Drive The Incredible Superhydrophobic Properties Of Soot, Ashton Bressler Jan 2024

A Precision-Controlled Investigation Into The Fundamentals Which Drive The Incredible Superhydrophobic Properties Of Soot, Ashton Bressler

Theses and Dissertations

A PRECISION-CONTROLLED INVESTIGATION INTO THE FUNDAMENTALS WHICH DRIVE THE INCREDIBLE SUPERHYDROPHOBIC PROPERTIES OF SOOT

By Ashton Bressler

A thesis submitted as a partial fulfilment of the Virginia Commonwealth University requirements for a Masters of Science at Virginia Commonwealth University.

Virginia Commonwealth University, 2024.

This thesis investigates a precision controlled superhydrophobic soot surface, composed of semi-rigid linked chains of spheres, with a radii of roughly 14um. These spheres have exceptionally useful hydrophobic properties due to; their large surface area, their large triple phase line length, their low area fraction of solid-liquid interface, their ability to deform, and their strength from both …


Shinners, Alexis E. Mabry Jan 2024

Shinners, Alexis E. Mabry

Theses and Dissertations

Shinners is a project that aims to examine the position of women in subcultures and capture conversations of women in subcultural sports. Within feminism, sociological constructs, campy horror, and personal experience I am manifesting the physical and mental obstacles faced in the subcultural sport of Bicycle Motocross (BMX) through photography, painting, collage, video, and sculpture. I interpret images posted to social media of injuries obtained while riding BMX as forms of empowerment, bodily gore as extreme evidence of participation, performative violence, valorizing the understanding of both the physical and psychological pain of failure, and the use of failure as a …


Points Of Contact, Giancarlo Venturini Jan 2024

Points Of Contact, Giancarlo Venturini

Theses and Dissertations

The work in Points of Contact arises from engaging love as it relates to distance, desire, and longing. This paper will analyze my painting practice and its evolution from the explicit to implicit. Specifically I am going to talk about my utilization of landscape painting to consider another way of expressing sexuality and queerness. I will explain how objects and landscapes are conduits for feelings that can intrinsically hold allegorical representations. This show is about searching through vast spaces to find points of connection in the natural world. I will talk about portals and the varied degrees of accessible windows …


Using Natural Language Processing To Understand The Lived Experiences Of People Identifying With Adhd: What Themes Emerge In Social Media Posts?, Gabby C. Scalzo Jan 2024

Using Natural Language Processing To Understand The Lived Experiences Of People Identifying With Adhd: What Themes Emerge In Social Media Posts?, Gabby C. Scalzo

Theses and Dissertations

Compared to the amount of research conducted on how to identify and understand children with Attention-Deficit Hyperactivity Disorder (ADHD), there has been relatively little work done to understand the lived experiences of adults with ADHD. Increased understanding of how adults with ADHD conceptualize themselves in the context of their diagnosis would help clinical experts tailor research and treatments to better serve these communities. However, there are several barriers towards conducting high-quality qualitative research, including time- and labor-intensity. This study, informed by qualitative research traditions, used innovative data sources (i.e., social media) and analytic techniques (i.e., machine learning) to reduce these …


On The Rebound: Resilience And Subjective Cognitive Symptoms In Cancer, Giuliana V. Zarrella Jan 2024

On The Rebound: Resilience And Subjective Cognitive Symptoms In Cancer, Giuliana V. Zarrella

Theses and Dissertations

Recent studies have shown a strong connection between resilience and subjective cognitive symptoms in clinical populations. However, there is limited understanding of this relationship in cancer survivors, and no studies examine whether resilience training could alleviate subjective cognitive symptoms in these patients. This study examined the relationship between subjective cognitive function and resilience in non-CNS cancer survivors who participated in a resiliency training intervention, at baseline and from pre- to post-intervention, as well as investigated potential influences of change in subjective cognition. Adult cancer survivors (N=275) participated in the Stress Management and Resilience Training-Relaxation Response Resilience Program (SMART-3RP) …


Preexisting Conditionings: Painting, Gaming And Narrative Play, Pia Bakala Jan 2024

Preexisting Conditionings: Painting, Gaming And Narrative Play, Pia Bakala

Theses and Dissertations

My work incorporates play, fantasy, and self-actualization through painting, sculpture, and video. In this essay, I will explore the ways in which my studio practice intersects with topics across fields of visual arts and in conjunction their theoretical frameworks. I will discuss the culminating body of work, tentatively titled Preexisting Conditionings, that my academic experience at VCU has fostered and trace its development across specific precursive works, as well as the cultural and intellectual touchstones influencing its creative impetus. In Preexisting Conditionings, I work primarily use oil painting, creating mostly representational figurative tableaus that correspond to narratives and characters I’m …


Extrusion-Based Additive Manufacturing Of Magnetic Heat Exchange Structures For Caloric Applications, Vaibhav Sharma Jan 2024

Extrusion-Based Additive Manufacturing Of Magnetic Heat Exchange Structures For Caloric Applications, Vaibhav Sharma

Theses and Dissertations

Currently, the commercial building sector accounts for 18% of total U.S. end-use energy consumption, of which almost a third was from on-site combustion of fossil fuels for space and water heating. Magnetic heat pumping (MHP) technology is an energy-efficient, sustainable, environmentally-friendly alternative to conventional vapor-compression cooling technology. Several MHP designs today are predicted to be highly energy efficient, on condition that suitable working materials can be developed. This materials challenge has proven to be daunting due to issues associated with intricate synthesis/post-processing protocols and complications related to shaping the mostly brittle magnetocaloric alloys into thin-walled channeled regenerator structures to facilitate …


A Critical Perspective On Supporting Parents In Facilitating Informal Steam Learning On Children's Early Literacy Development, Suzanne G. Alexandre Jan 2024

A Critical Perspective On Supporting Parents In Facilitating Informal Steam Learning On Children's Early Literacy Development, Suzanne G. Alexandre

Theses and Dissertations

Considering that parents/caregivers and home environment play an influential role in a child’s school readiness and future academic success, this study sought to support parents in using facilitation strategies to engage their child in informal learning at home. In order to examine if access to support for parents of preschoolers influenced parents’ confidence in their ability to facilitate informal learning at home, the project used informal STEAM learning, for context. The study also examines the potential impact of informal STEAM learning on children's school readiness and early literacy skills and the intersections of parent involvement, STEAM, and school readiness through …


Exploring The Experiences Of Refugee Youth In Public Schools: An Ethical Phenomenological Inquiry, Hilary T. Stim Jan 2024

Exploring The Experiences Of Refugee Youth In Public Schools: An Ethical Phenomenological Inquiry, Hilary T. Stim

Theses and Dissertations

The study outlined in this dissertation focuses on the intersection between refugee youth between the ages of 13-18 and the United States public school, specifically the manner in which refugee youth experience institutionalized education. It utilizes ethical phenomenology as a means to amplify the voices of refugee students and to centralize the students' experiences, thoughts, and ideas related to education The study was framed by one research question that is addressed to the participants: “What is it like being a student in a public school?” Seven students took part in the study. Collaborative dialogues took place with the participants across …


Exploring Drivers Of Sex-Based Disparities In Relapsing Multiple Sclerosis, Stephanie K. Buxhoeveden Jan 2024

Exploring Drivers Of Sex-Based Disparities In Relapsing Multiple Sclerosis, Stephanie K. Buxhoeveden

Theses and Dissertations

Females are three times more susceptible to relapsing multiple sclerosis (MS) and males typically have more severe disease, but the molecular underpinnings of these sex-based disease disparities are unknown and represent a critical knowledge gap.Subject Population: Blood samples from a demographically homogenous group of treatment naïve males and females with relapsing-MS and healthy controls. Research Design: Cross-sectional combinatorial omics pilot study. Instruments: Whole transcriptomic analysis with messenger RNA (mRNA) expression profiling using next generation sequencing (RNA-seq) and micro-RNA (miRNA) expression using NanoString technology. Aim 1) Identify and compare the actively expressed mRNAs in the transcriptome of males and …


Exploring The Relationship Of Intact Limb Knee Joint Loading With Step Lengths And Step Length Symmetry In Individuals With Lower Limb Amputation, Edward D. Syrett Jan 2024

Exploring The Relationship Of Intact Limb Knee Joint Loading With Step Lengths And Step Length Symmetry In Individuals With Lower Limb Amputation, Edward D. Syrett

Theses and Dissertations

Individuals with unilateral lower limb amputation (LLA) frequently experience intact limb knee pain, dysfunction, and osteoarthritis. These problems can worsen pre-existing reductions in mobility and quality of life that this population regularly experiences. It is widely accepted that knee joint loading is implicated in the development of knee joint issues, and intact limb knee joint load alterations are thought to be widespread in individuals with LLA. Prior work suggests that gait deviations frequently present in this population may be a contributory cause of these altered forces. These deviations can take many forms, but individuals with LLA commonly demonstrate alterations in …


Investigating The Regulation Of Epithelial-Mesenchymal Transition Through Fibronectin-Mediated Tgf-Β1 Mechanotransduction Using In Vitro Models Of Triple-Negative Breast Cancer, Michael M. Sofroniou Jan 2024

Investigating The Regulation Of Epithelial-Mesenchymal Transition Through Fibronectin-Mediated Tgf-Β1 Mechanotransduction Using In Vitro Models Of Triple-Negative Breast Cancer, Michael M. Sofroniou

Theses and Dissertations

TGF-β1 is a potent regulator of epithelial-mesenchymal transtion (EMT), a cellular
transdifferentation process that promotes cellular motility and matrix remodeling, critical to tumorigenesis and metastasis. TGF-β1-induced EMT promotes the assembly of FN, which synergistically binds latent TGF-β1 to aid in its activation. The purpose of of this work is to further probe the effects of autocrine TGF-β1 signaling during EMT progression by utilizing CRISPR-Cas9 deletion of the TGFB1 gene in in vitro models of triple-negative breast cancer. The studies outlined in this work demonstrate that autocrine TGF-β1 maintains a baseline level of mesenchymal marker expression. It also functions to desensitize …


Optimizing Deep Inspiration Breath Hold Technique For Personalized Breast Cancer Radiotherapy, Srinidhi Rajagopalan Jan 2024

Optimizing Deep Inspiration Breath Hold Technique For Personalized Breast Cancer Radiotherapy, Srinidhi Rajagopalan

Theses and Dissertations

The purpose of this research is entrenched in advancing the practice of 3D Conformal Radiation Therapy (3D CRT) for breast cancer patients by meticulously evaluating the impact of different Deep Inspiration Breath Hold (DIBH) techniques on dosimetric parameters. This study aims to ascertain the quantitative benefits of varied breathing techniques, primarily focusing on the 'Ultimate DIBH' method's efficacy in sparing critical organs such as the heart and lungs.

The comprehensive analysis of different DIBH techniques in this research is not merely an academic exercise but is geared towards substantiating the hypothesized advantages of these techniques with empirical data. By generating …


Evaluation Of Cervical Dentin Removal After Orifice Shaping In Maxillary Premolars: A Micro Ct Study, Abdulaziz Mallik Jan 2024

Evaluation Of Cervical Dentin Removal After Orifice Shaping In Maxillary Premolars: A Micro Ct Study, Abdulaziz Mallik

Theses and Dissertations

Objective: The research aims to compare the volume and percentage of pericervical dentin removed by Gates Glidden Drills, ProTaper SX, and a 20-06 Rotary File.

Methods: A total of 24 extracted two-rooted maxillary first premolars were divided into three groups (n=8) and were coronally flared using either Gates-Glidden Drills, ProTaper Gold SX, or a 20-06 Brasseler Endosequence CM Rotary File. Pre- and post-flaring micro-CT scans were obtained. The dentin volume of the buccal canals was measured from the chamber floor and 2 mm apically in the buccal canal only. Data were analyzed using the ANCOVA test to compare dentin removal …


The Effect Of Experienced Compassion At Work On Nursing Home Certified Nursing Assistants' Well-Being And Turnover Intentions, Kristin M. Macdonald Jan 2024

The Effect Of Experienced Compassion At Work On Nursing Home Certified Nursing Assistants' Well-Being And Turnover Intentions, Kristin M. Macdonald

Theses and Dissertations

Statement of problem and objectives: Could experienced compassion at work alleviate nursing home certified nursing assistant (CNA) burnout? This study investigates whether experienced compassion at work predicts higher well-being (meaningfulness of work, psychological vitality, and resilience) for CNAs, and if well-being predicts lower turnover intentions.

Procedure followed: This is a prospective, observational, survey-based study with three timepoint data collection. Convenience sampling of Kansas and Virginia NHs was conducted (n=13). All CNAs working at the NHs were study eligible. CNAs received gift cards with laddered incentives for ongoing participation. There was in-person administration of a CNA survey at each timepoint. …


Biophilia: Developing A Taste For Care, Che'leah Shannon Jan 2024

Biophilia: Developing A Taste For Care, Che'leah Shannon

Theses and Dissertations

People in materially developed cultures spend over 90% of their lives in buildings (Evans & McCoy, 1998). Commencing with the industrial revolution these materially developed cultures see most of their populus moving from the countryside to the city in search of work and better lives. The city, an urban and modern development of densely packed peoples, buildings, and infrastructure, has developed as an efficient solution to meet the needs of a cosmopolis.

The city has developed widely without a necessity or place for nature. The ground outside is paved with concrete, efficient and comfortable for travel, buildings are built high …


Learning Curve: Designing An Inclusive Early Childhood Learning Center, Sarah Alrumayh Jan 2024

Learning Curve: Designing An Inclusive Early Childhood Learning Center, Sarah Alrumayh

Theses and Dissertations

This research centers on the improvement of early childhood education environments in hopes to reduce the disparities in outcomes among children aged 2-6, widely known as "the achievement gap." It sheds light on designing an inclusive, child-centered school for students with specific learning disabilities (SLD) and speech or language impairments (SLI). Drawing on the IDEA (Individuals with Disabilities Education Act), it underscores the benefits of integrating students with special education needs into mainstream education, thereby fostering inclusive learning environments. (IDEA, 1975).

The research question probes how to create a nurturing and adaptable school environment tailored to the diverse needs of …


In Shame I Will Find Paradise, Taehee Whang Jan 2024

In Shame I Will Find Paradise, Taehee Whang

Theses and Dissertations

As a Korean American non-binary digital artist and designer, my recent explorations have focused on using voice as a medium to articulate nuanced feelings of displacement and the intricate relationships between language, identity, and expression. This journey expands beyond my personal experiences with gender dysphoria, delving into the lives of non-binary and transgender individuals undergoing gender-affirming voice therapy. Through my thesis research, I have developed interactive multimedia installations inspired by dialogues with individuals such as Umico Niwa, who traveled to Korea for voice feminization surgery, and Jeong Yoon Lee from Hyperlink Press, a four-year participant in Hormone Replacement Therapy (HRT). …


Sense Make Before Book, Bradley Sinanan Jan 2024

Sense Make Before Book, Bradley Sinanan

Theses and Dissertations

“Sense Make Before Book” is an Indo-Caribbean turn of phrase which refers to common sense being more important than book smarts. My sister sent me a post the other day on Instagram of an Trinidadian woman using this phrase, saying it was one of Indo-Caribbean origin. I was interested and asked my mom about it. My mom says that when she was younger my grandpa said it often around their house in Princes Town, Trinidad and Tobago. This adage feels charged thinking about the history of indenture and its effects on the Indo-Caribbean diaspora.

The written word of archival history …


Illuminating Function And Enabling Inhibition At The Protein-Membrane Interface Of Glutathione Peroxidase 4., Courtney L. Labrecque Jan 2024

Illuminating Function And Enabling Inhibition At The Protein-Membrane Interface Of Glutathione Peroxidase 4., Courtney L. Labrecque

Theses and Dissertations

Membrane proteins act as gateways to cells and are responsible not only for signaling, lipid transport, and cellular homeostasis, but they are also integral in disease pathologies. One class of membrane proteins, peripheral membrane proteins (PMPs), reside in aqueous compartments of the cell until they are recruited to the membrane to perform their function. Glutathione peroxidase 4 (GPx4) is a PMP enzyme responsible for engaging the membrane and reducing lipid hydroperoxides, thereby preventing cellular death via ferroptosis. Due to its central function surrounding ferroptosis, GPx4 is an interesting drug target that has recently gained interest for inflammatory diseases as well …


Obesity Knowledge And Bmi In Caregiver-Adolescent Dyads: A Descriptive Comparative Pilot Study, John Sykes, John Sykes Jan 2024

Obesity Knowledge And Bmi In Caregiver-Adolescent Dyads: A Descriptive Comparative Pilot Study, John Sykes, John Sykes

Theses and Dissertations

Abstract

Background: The prevalence of obesity and associated health risks and costs continue to increase. The majority of these health and cost ramifications manifest in adulthood, making it imperative to intercept the problem during childhood. Unfortunately, an overwhelming majority of the research surrounding adolescents and obesity to date involves subjects that are already overweight or obese, and the focus of those interventions are on secondary and tertiary prevention. Focusing on primary prevention of childhood obesity could ultimately decrease the incidence, prevalence, and disease-related burden to society. It is posited that the 20% difference in obesity prevalence between adults and children …


A Walk In The Woods, Caitlin Mclean Jan 2024

A Walk In The Woods, Caitlin Mclean

Theses and Dissertations

A connection with nature fosters increased appreciation, admiration, and responsibility toward the natural environment, thus encouraging the mindful use of its resources and preservation of both species and their habitats. Defined by Mayer and Frantz (2004) as an “experiential sense of oneness with the natural world”, this connection is more important now than ever in this highly digital era. Studies indicate that limited exposure to nature can negatively impact the activation of neural pathways associated with pro-environmental attitudes and behaviors (Chawla, 2020), while further research shows that engagement with the outdoors during childhood as a significant life experience (Chawla, 1998), …


Elucidation Of The Optical Properties Of Si And Si-Ge Alloy Nanostructures With Visible To Near-Ir Photoluminescence, Griffin Spence Jan 2024

Elucidation Of The Optical Properties Of Si And Si-Ge Alloy Nanostructures With Visible To Near-Ir Photoluminescence, Griffin Spence

Theses and Dissertations

Silicon and silicon-germanium alloy nanostructures have garnered increasing attention in the past 25 years due to their favorable optical properties, visible to near-IR luminescence, and inherently low toxicity. While many synthetic routes have been discussed in the literature, the high-temperature, solid-state disproportionation of hydrogen silsesquioxane (HSQ) has become the most popular way to produce highly crystalline, size-tunable Si and Si-based nanostructures (NCs). It has been shown in this work that maximum annealing temperature from 450°-1100°C and the addition of GeI2or SnCl4 precursors can be used to achieve different morphologies, alloying efficiency, and sizes. Directly annealing HSQ from …


Politics Of Being A Lover: In Art, (Space) And Kink, Rabeeha Adnan Jan 2024

Politics Of Being A Lover: In Art, (Space) And Kink, Rabeeha Adnan

Theses and Dissertations

Politics of being a lover: in art, (space) and kink explores my relationship with my practice through observations and stories that draw parallels with romance and kink. Narrated as love affairs turned into complex commitment, it shuffles through logics of structural power, control, and communication in the context of praxis and art institutions.


Mathematical Modeling And Analysis Of Inflammation And Tissue Repair: Lung Inflammation And Wound Healing In Corals Under Stress, Quintessa Hay Jan 2024

Mathematical Modeling And Analysis Of Inflammation And Tissue Repair: Lung Inflammation And Wound Healing In Corals Under Stress, Quintessa Hay

Theses and Dissertations

A variety of insults, including tissue injury and/or exposure to pathogen, elicit an immune response in many organisms. An improperly regulated immune response can result in deleterious effects to the organism. Here we present models for lung injury in young and old mice and models for wound healing in coral reefs.

It is well known that the immune response becomes less effective in older individuals. This is of particular interest in pulmonary insults such as ventilator induced lung injury (VILI) or lung infection. We extended a mathematical model for the inflammatory response to VILI and used experimental data to select …


Stereotypes Of A Black Man Misunderstood: The Experiences And Development Of Black Men With Bipolar Disorder On College Campuses, Gerron Scott Jan 2024

Stereotypes Of A Black Man Misunderstood: The Experiences And Development Of Black Men With Bipolar Disorder On College Campuses, Gerron Scott

Theses and Dissertations

Black men graduate from universities at a lower rate compared to other groups. Students with disabilities also graduate at a lower rate. When the two groups intersect, the results can be disastrous. Black men with bipolar disorder face a host of problems on college campuses. From a lack of sense of belonging to trouble in class, they struggle to stay afloat in college. The purpose of this study was to document the experiences and development of Black men with bipolar disorder on college campuses. A grounded theory approach was used in this study. Grounded theory was chosen because it leads …


"I Call Them Supermoms": Therapists' Reflections On The Impact Of Youth Sexual Offending On Latina Mothers, Mauricio P. Yabar Jan 2024

"I Call Them Supermoms": Therapists' Reflections On The Impact Of Youth Sexual Offending On Latina Mothers, Mauricio P. Yabar

Theses and Dissertations

Families of youth who have sexually offended often suffer significant collateral consequences following the discovery of the sexual offense. Samples in research with these families disproportionately consist of mothers and other female parental figures. This is rarely acknowledged in the literature, and the experiences of these mothers have not been explicitly examined. In addition, research on the experiences of these families has largely ignored factors related to race and ethnicity. This is a significant oversight considering the prevalence of systemic racism and discrimination in the United States, particularly in the systems with which these families must interact (e.g., juvenile justice …


The Neural Mechanisms Of Inter-Friend Aggression, Wyatt Brown Jan 2024

The Neural Mechanisms Of Inter-Friend Aggression, Wyatt Brown

Theses and Dissertations

Decades of research concerns intimate partner aggression (IPA). While important to understand and prevent, investigations of IPA largely ignore another vital social relationship: close friendships. To investigate aggression between close friends – inter-friend aggression (IFA) – functional neuroimaging analyses enable to assessment of neural activity and mental representations of aggression in different social relationships. As such, 98 participants completed the well-validated Taylor Aggression Paradigm modified for a magnetic resonance environment against their current romantic partner, a close friend, and a stranger. Univariate analyses assessed the differences in the degree of neural activity and the role of Narcissism and negative urgency …