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Radiation Therapy Treatment Plan Optimization Accounting For Random And Systematic Patient Setup Uncertainties, Joseph Moore Apr 2011

Radiation Therapy Treatment Plan Optimization Accounting For Random And Systematic Patient Setup Uncertainties, Joseph Moore

Theses and Dissertations

External-beam radiotherapy is one of the primary methods for treating cancer. Typically a radiotherapy treatment course consists of radiation delivered to the patient in multiple daily treatment fractions over 6-8 weeks. Each fraction requires the patient to be aligned with the image acquired before the treatment course used in treatment planning. Unfortunately, patient alignment is not perfect and results in residual errors in patient setup. The standard technique for dealing with errors in patient setup is to expand the volume of the target by some margin to ensure the target receives the planned dose in the presence of setup errors. …

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Wilms’ Tumor-1 (Wt1) Protein Expression In Glioma Cells Actuates Cellular Invasiveness- Identifying Its Target Genes, Archana Chidambaram Apr 2011

Wilms’ Tumor-1 (Wt1) Protein Expression In Glioma Cells Actuates Cellular Invasiveness- Identifying Its Target Genes, Archana Chidambaram

Theses and Dissertations

Previous studies in our laboratory demonstrated the expression of WT1 in a significant number of glioma cells and established its role in promoting tumor cell proliferation. Here, we noted the effect(s) of manipulating WT1 levels on the expression levels of genes that were previously shown to be regulated by WT1. We found no correlation between the expression levels of WT1 and PDGF-A, Snai1 and E-cadherin and a consistent inverse correlation between WT1 and IGF-1R expression in U251-MG cells. To ascertain whether the increased IGF-1R levels resulting from WT1 silencing could account for decreased cellular proliferation, we utilized siRNA mediated knockdown …

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Commonwealth Times 2011-04-21 Apr 2011

Commonwealth Times 2011-04-21

Commonwealth Times, 1969-

No abstract provided.

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Characterization Of A Blast Wave Device And Blast Wave Induced Traumatic Brain Injury In A Rat Model By Magnetic Resonance Imaging And Spectroscopy, Frank Corwin Apr 2011

Characterization Of A Blast Wave Device And Blast Wave Induced Traumatic Brain Injury In A Rat Model By Magnetic Resonance Imaging And Spectroscopy, Frank Corwin

Theses and Dissertations

Blast wave induced traumatic brain injury (bTBI) is a modality of injury that has come into prominence at the current time due to the large number of military and civilian personnel who have experienced the localized shock wave produced by explosive devices. The shock wave will travel concentrically outward from the explosive center, being absorbed and transmitted thru soft objects, such as tissue, and reflecting off stationary obstructions. Transmission and absorption in tissues can result in a number of physiological measureable injuries, the most common of which being what is frequently called “blast lung”. Blast lung involves the spalling effect …

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Dental Plan Performance With Medicaid Reform In Virginia, James Reed Apr 2011

Dental Plan Performance With Medicaid Reform In Virginia, James Reed

Theses and Dissertations

Purpose: To assess the effect of dental Medicaid reforms in the state of Virginia on dental plan performance. Methods: This project is a retrospective cohort study of 825,000 dental claims obtained from the Virginia Department of Medical Assistance Services. This cohort includes dental claims for children enrolled in Virginia’s Medicaid program from July 1, 2002 through June 30, 2008. The independent variable was enrollment pre or post policy reform with July 1, 2005 as the period dividing date. The dependent variable was dental benefit utilization measured as the average number of restorative, preventative, and total procedures. Statistical methods include Welch’s …

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A Municipal Exigency: An Exploration Of The Correlation Of Physical And Social Incivilities On The Decline Of Residential Property Values In Richmond, Va, Jay Brown Apr 2011

A Municipal Exigency: An Exploration Of The Correlation Of Physical And Social Incivilities On The Decline Of Residential Property Values In Richmond, Va, Jay Brown

Theses and Dissertations

This dissertation examines the correlation between incivilities, indicators of urban blight, and single-family residential property values in the City of Richmond, Virginia. Through the utilization of a mixed methods research methodology, this dissertation assesses whether specific incivilities, structural characteristics of properties, or community demographics have an adverse influence on property values. Three separate methodologies were utilized in this research including a time series assessment, focus group and individual interviews, and a cross sectional design. The findings from the time series analysis indicate that property values increased every year over a five year period and that there were variances in property …

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Evaluating Dental Surgery Post-Operative Pain In Children Following Treatment Under General Anesthesia, Malinda Husson Apr 2011

Evaluating Dental Surgery Post-Operative Pain In Children Following Treatment Under General Anesthesia, Malinda Husson

Theses and Dissertations

Purpose: The purpose of this pilot study was to determine if there is a difference in post-operative pain experience for children following dental restorations and/or extractions under general anesthesia (GA), with and without local anesthetic (LA). The alternative hypothesis is that children will experience less post-operative discomfort and soft tissue trauma when using intra-ligamental local anesthetic during the intra-operative time period. Methods: Patients were recruited for this single blind, randomized, prospective cohort study with the following inclusion criteria, children age 2-6 years requiring general anesthesia for dental treatment. Patients were randomized into categories of either receiving a standardized local anesthetic …

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The Influence Of Perceptual Accuracy On Willingness To Seek Help Among College Freshmen, Kathryn Conley Apr 2011

The Influence Of Perceptual Accuracy On Willingness To Seek Help Among College Freshmen, Kathryn Conley

Theses and Dissertations

OBJECTIVE: The current study explored the applicability of the social norms approach to a new domain of study: psychological help-seeking. A number of questions that must be answered to determine whether the social norms model can be applied effectively to the help-seeking domain guided the study. METHOD: Data were collected from freshmen at five colleges and universities in the Mid-Atlantic region (N = 3021) during freshman orientation week. The study used a cross sectional design to examine personal attitudes and behaviors related to help-seeking as well as perceptions about others’ attitudes and behaviors related to help-seeking. RESULTS: Most participants reported …

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How Virginia Public School Superintendents Spend Their Time, Eric Armbruster Apr 2011

How Virginia Public School Superintendents Spend Their Time, Eric Armbruster

Theses and Dissertations

The purpose of this research is to examine how Virginia public school superintendents spend their time. The primary goal of this study is to determine the differences in how superintendents allocate their time in regards to their involvement with specific tasks. This descriptive study is designed to determine the level of involvement of superintendents throughout the state of Virginia in the areas of fiscal management, facility management, personnel, student personnel and special services, support services, instruction and curriculum, and community relations. This study investigates how much time is spent by superintendents in specific performance areas as defined by the Guidelines …

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Predicting The Diffusion Of Next Generation 9-1-1 In The Commonwealth Of Virginia: An Application Using The Deployment Of Wireless E9-1-1 Technologies, Dorothy Spears-Dean Apr 2011

Predicting The Diffusion Of Next Generation 9-1-1 In The Commonwealth Of Virginia: An Application Using The Deployment Of Wireless E9-1-1 Technologies, Dorothy Spears-Dean

Theses and Dissertations

This study examines the deployment of Wireless E9-1-1 Phase One and Wireless E9-1-1 Phase Two as a diffusion of innovation. The research method used in this study is a cross-sectional study employing secondary data in a discriminant function analysis. The study population is Virginia units of local governments (95 counties and 39 cities) that had not deployed Wireless E9-1-1 Phase One or Wireless E9-1-1 Phase Two as of January 1, 2001. The period of time included in this study is from 2001 to 2006. The purpose of the study is to assess the overall accuracy of the three principle theories …

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Layers Of Meaning, Joan Wiberg Apr 2011

Layers Of Meaning, Joan Wiberg

Theses and Dissertations

My artwork reflects my search for my own artistic voice. Life demands examination from me at inconvenient times, but with the intention of growing as a person I proceed willingly, and as an artist, equipped with a paintbrush. My search has led me to discover new materials and techniques and my structured self-reflection has uncovered a new source of inspiration. I now combine the physical layering of art materials with layers of personal meaning as well. My work has an autobiographical theme which I have interpreted through the filter of my sense of humor. Working so intimately with my own …

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Organizational Culture And Partnership Process: A Grounded Theory Study Of Community-Campus Partnerships, Kready Sharon Foreman Apr 2011

Organizational Culture And Partnership Process: A Grounded Theory Study Of Community-Campus Partnerships, Kready Sharon Foreman

Theses and Dissertations

Community engagement initiatives have experienced an increase in attention, appreciation, and participation among those in academic, nonprofit, and other community-based organizations over the past two decades. The purpose of this study is to explore the meanings of community-campus partnerships among stakeholders in the community and in academia towards the goal of generating a theory grounded in these data that will concomitantly contribute to the social work profession and the community engagement movement. Using as its foundation the shared interest among the social work profession and the community engagement movement on values and ethics, this study utilizes a traditional grounded theory …

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Is Gait Training With The Elliptically Based Robotic Gait Trainer (Ebrgt) Feasible In Ambulatory Patients After Stroke?, J. Cortney Bradford Apr 2011

Is Gait Training With The Elliptically Based Robotic Gait Trainer (Ebrgt) Feasible In Ambulatory Patients After Stroke?, J. Cortney Bradford

Theses and Dissertations

In response to the potential benefits of task specific training in rehabilitation of gait after stroke and the need for affordable, simple ways to implement it, our group designed the elliptically based robotic gait trainer (EBRGT). A design review of the EBRGT, covering the design goals, an overview of the mechanical and electrical design, and a discussion of the novelty of the device and why it may be beneficial for individuals with hemiparesis secondary to stroke is discussed (Chapter 2). To characterize the new device, a study was performed to determine if the EBRGT produced a gait pattern that mimicked …

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Interdisciplinary Teamwork Pedagogy, Carole Ivey Apr 2011

Interdisciplinary Teamwork Pedagogy, Carole Ivey

Theses and Dissertations

The purpose of this study was to describe the interdisciplinary teamwork pedagogy of the Leadership Education in Neurodevelopmental and Related Disabilities (LEND) training programs, specifically the content focus, instructional methods, and assessment practices. LEND programs are a national network providing long-term, graduate interdisciplinary training through federal funds from the Health Resources and Services Administration's Maternal Child Health Bureau. This study used a mixed method approach to describe the interdisciplinary teamwork pedagogy of LEND training programs. The study occurred in three stages: 1) a survey of LEND training directors, 2) a survey of LEND interdisciplinary teamwork instructors, and 3) document review …

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Do Body Image And Gender Role Attitudes Mediate The Relationship Between Media Exposure And Sexual Risk Behavior In College Students?, Vivian Rodriguez Apr 2011

Do Body Image And Gender Role Attitudes Mediate The Relationship Between Media Exposure And Sexual Risk Behavior In College Students?, Vivian Rodriguez

Theses and Dissertations

Despite growing awareness of the HIV/AIDS pandemic and educational efforts to provide accurate information about sexually transmitted diseases (STD), young adults continue to engage in risky sexual practices that increase their vulnerability of acquiring an STD, including inconsistent condom use. Research has gathered ample evidence to suggest that the media, in particular television consumption, is directly linked with sexual risk, yet less is known about the potential mechanisms that may be driving this link. The present study examines body image and gender role attitudes as two potential mediators of this relationship. Three-hundred and four undergraduate students (73% female; 64% White) …

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Forgotten, Found, Forgiven, Megan Mattax Apr 2011

Forgotten, Found, Forgiven, Megan Mattax

Theses and Dissertations

My work deals with loss and the emotions entangled with grief. To do this, I incorporate text, found organic imagery, bound fibers, and hand-spun threads into my work. I relate these objects and materials to the stages of a woman’s life, which is a symbolic reference to the nymph, mother, and crone and the transformation from life to death. The background surface of information in my two-dimensional work serves as a cryptic guide to the actual meaning of things. All the excerpted information comes from medical or general knowledge dictionaries. This ground of text is methodically planned but also spontaneously …

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Factors Associated With Hospital Entry Into Joint Venture Arrangements With Ambulatory Surgery Centers, Reethi Iyengar Apr 2011

Factors Associated With Hospital Entry Into Joint Venture Arrangements With Ambulatory Surgery Centers, Reethi Iyengar

Theses and Dissertations

This study presented an empirical analysis of the key market, regulatory, organizational, operational and financial factors associated with hospital entry into joint venture (JV) arrangements with Ambulatory Surgery Centers (ASCs) as examined through the framework of resource dependency theory complimented with neo-institutional theory. This study used a cross sectional design to examine hospitals that entered into a joint venture arrangement with ASCs in 2006 and 2007. The data for this study were drawn from five main sources: the American Hospital Association Annual Survey (AHA), the Area Resource File (ARF), the CMS (Center for Medicare and Medicaid Services) minimum dataset, the …

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Examining California’S Assembly Bill 1629 And The Long-Term Care Reimbursement Act: Did Nursing Home Nurse Staffing Change?, Matthew Krauchunas Apr 2011

Examining California’S Assembly Bill 1629 And The Long-Term Care Reimbursement Act: Did Nursing Home Nurse Staffing Change?, Matthew Krauchunas

Theses and Dissertations

California’s elderly population over age 85 is estimated to grow 361% by the year 2050. Many of these elders are frail and highly dependent on caregivers making them more likely to need nursing home care. A 1998 United States Government Accountability Office report identified poor quality of care in California nursing homes. This report spurred multiple Assembly Bills in California designed to increase nursing home nurse staffing, change the state’s Medi-Cal reimbursement methodology, or both. The legislation culminated in Assembly Bill (AB) 1629, signed into law in September 2004, which included the Long-Term Care Reimbursement Act. This legislation changed the …

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Commonwealth Times 2011-04-11 Apr 2011

Commonwealth Times 2011-04-11

Commonwealth Times, 1969-

No abstract provided.

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Sensory Modulation Disorder And Schizophrenia: Linking Behavioral Measures, Linda Olson Apr 2011

Sensory Modulation Disorder And Schizophrenia: Linking Behavioral Measures, Linda Olson

Theses and Dissertations

Schizophrenia is a devastating disorder affecting millions of people in the United States. Studies leading to new understanding of and intervention for this disorder are essential, as current interventions are minimally effective. The end result is high rates of re-hospitalization, impaired occupational performance and decreased community reintegration. According to the Diagnostic and Statistical Manual of Mental Disorders, symptoms of schizophrenia are categorized as positive or negative, with both types of symptoms impacting successful occupational engagement. Based on behavioral observations occupational therapists have hypothesized that this population may also experience sensory modulation disorder (SMD). Although electrophysiological studies support the presence of …

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An In Vitro Comparison Of Cyclic Fatigue Of Profile® Vortex™ And Endosequence™ Rotary Nickel-Titanium Files, Fawaz Al-Foraih Apr 2011

An In Vitro Comparison Of Cyclic Fatigue Of Profile® Vortex™ And Endosequence™ Rotary Nickel-Titanium Files, Fawaz Al-Foraih

Theses and Dissertations

The purpose of this study was to determine the number of rotations to fracture (cyclic fatigue) of the Profile® Vortex™ files (Dentsply Tulsa Dental Specialties, Tulsa, OK) compared to the EndoSequence™ files (Brasseler USA, Savannah, GA) using an in-vitro apparatus simulating a curved canal. Two hundred Profile® Vortex™ files of 25mm length were divided equally into ten groups, one for each of the Profile® Vortex™ files 20/0.04, 20/0.06, 25/0.04, 25/0.06, 30/0.04, 30/0.06, 35/0.04, 35/0.06, 40/0.04, and 40/0.06. Two hundred EndoSequence™ files of 25mm length were divided equally into ten groups of the same tip and taper sizes analogous to the …

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A Comparative Study Of Rotary Instrumentation Of The Maxillary First Premolar Buccal Root Utilizing Cone Beam Computed Tomography, Stephan Zigo Apr 2011

A Comparative Study Of Rotary Instrumentation Of The Maxillary First Premolar Buccal Root Utilizing Cone Beam Computed Tomography, Stephan Zigo

Theses and Dissertations

The study objective was to determine cementum-dentin wall thickness along the furcation groove in maxillary bifurcated first premolars after preparation with three successively larger, 0.04 tapered, nickel titanium rotary files. Pre-instrumentation and post-instrumentation imaging was accomplished utilizing Cone Beam Computed Tomography. All data was analyzed using an ANOVA. Instrumentation resulted in a significant reduction in dentin-cementum wall thickness (p < .001). At mid-groove, predicted dentin-cementum wall thickness (95% CI) was equal to or less than the proposed standard (0.50 mm) for apical file sizes 30, 35, and 40 respectively. Instrumentation of the mid-groove in maxillary first premolars reduces dentin-cementum wall thickness to levels that may be insufficient to ensure tooth integrity.

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Violations Of The Divine: Forgiveness Of Ingroup Transgressors Within Church Congregations Of The Christian Faith, Chelsea Greer Apr 2011

Violations Of The Divine: Forgiveness Of Ingroup Transgressors Within Church Congregations Of The Christian Faith, Chelsea Greer

Theses and Dissertations

Research on forgiveness has been expanding rapidly in the last decade with a subset of studies looking at how religious people forgive. A discrepancy persists between Christians’ level of valuing forgiveness and forgiveness of actual transgressions. Several methodological issues and offense-specific variables have been presented as explanations. This present thesis examines the role of the congregation as a group identity, and applies it to a theory of relational spirituality, as a measure of the relationship between a victim and the Sacred. No existing research has polled congregants about offense-specific forgiveness of church peers. I collected data from members of Christian …

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Commonwealth Times 2011-05-02 Apr 2011

Commonwealth Times 2011-05-02

Commonwealth Times, 1969-

No abstract provided.

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Age Differences In Long-Term Adjustment And Psychosocial Outcomes In A Large Multi-Site Sample 5-10 Years After Heart Transplant, Andrea Shamaskin Apr 2011

Age Differences In Long-Term Adjustment And Psychosocial Outcomes In A Large Multi-Site Sample 5-10 Years After Heart Transplant, Andrea Shamaskin

Theses and Dissertations

Research on age differences in heart transplant patients has focused primarily on medical outcomes, with mixed findings regarding mortality and morbidity rates and limited research regarding age differences in psychosocial and quality of life outcomes. To gain a more complete understanding of psychosocial adjustment after heart transplant, this study examined age differences in: satisfaction with quality of life, satisfaction with social support, depressive symptoms, negative affect, symptom distress, stress related to heart transplant, overall health functioning, coping strategies, and aspects of adherence. Results indicate that older patients, compared to younger patients, report better adjustment and quality of life across numerous …

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Commonwealth Times 2011-03-31 Mar 2011

Commonwealth Times 2011-03-31

Commonwealth Times, 1969-

No abstract provided.

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The Discrepancy Between Subjective And Objective Measures Of Sleep In Older Adults Receiving Cbt For Comorbid Insomnia, Hannah Lund Mar 2011

The Discrepancy Between Subjective And Objective Measures Of Sleep In Older Adults Receiving Cbt For Comorbid Insomnia, Hannah Lund

Theses and Dissertations

Clinical research on insomnia has observed that many individuals with this sleep disorder exhibit a significant discrepancy between their subjective reports of symptom severity and objective measures of the same parameters. This study sought to more closely examine this discrepancy by comparing sleep diary estimates with polysomnography data in a population of 60 older adults with comorbid insomnia. Consistent with previous research, results show that participants significantly underestimated sleep efficiency and total sleep time and significantly overestimated sleep onset latency. Participants receiving CBT-I exhibited significantly reduced discrepancy at post-treatment, particularly with regard to sleep latency, compared to those in a …

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Commonwealth Times 2011-03-28 Mar 2011

Commonwealth Times 2011-03-28

Commonwealth Times, 1969-

No abstract provided.

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Determinants Of Clergy Behaviors Promoting Safety Of Battered Korean Immigrant Women, Yoon Joon Choi Mar 2011

Determinants Of Clergy Behaviors Promoting Safety Of Battered Korean Immigrant Women, Yoon Joon Choi

Theses and Dissertations

Studies have shown that not only are clergy members the first persons from whom battered women seek help, but also a great number of clergy counsel battered women every year (Martin, 1989; Rotunda, Williamson, & Penfold, 2004). The role of the church and clergy are especially critical for the Korean immigrant community in the U.S. because Korean immigrants greatly underutilize existing services and rely heavily on their respective churches for assistance with various issues, including domestic violence (Boodman, 2007; Kim, 1997). Korean churches and clergy members have the potential to be active partners in providing intervention services and to serve …

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Screening Prostate Specific Antigen Effects On Racial Disparate Mortality: A Propensity Score Analysis, R. David Mcnally Mar 2011

Screening Prostate Specific Antigen Effects On Racial Disparate Mortality: A Propensity Score Analysis, R. David Mcnally

Theses and Dissertations

ABSTRACT SCREENING PROSTATE SPECIFIC ANTIGEN EFFECTS ON RACIAL DISPARATE MORTALITY: A PROPENSITY SCORE ANALYSIS By R. David McNally, Ph.D., M.S.H.A. A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University. Virginia Commonwealth University, 2011 Dissertation Chair: Jeffrey S. Legg, Ph.D., Associate Professor and Chair, Doctoral Program in Health Related Sciences Department of Radiation Sciences Prostate cancer is the most commonly diagnosed cancer among men in the United States. It is frequently cited that racial disparities in mortality between Caucasian and African American men with localized prostate cancer exist. In addition, …

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