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Articles 10291 - 10320 of 14284
Full-Text Articles in Entire DC Network
Contributors
Explorations in Ethnic Studies
Notes on contributors to Explorations in Ethnic Studies, Volume 16, Issue 2, 1993
Explorations In Ethnic Studies
Immunomodulatory Effects Of Transforming Growth Factor-Β On T Lymphocytes, Thomas Harris Inge
Immunomodulatory Effects Of Transforming Growth Factor-Β On T Lymphocytes, Thomas Harris Inge
Theses and Dissertations
Transforming growth factor-β1 (TGFβ) is a peptide cytokine implicated in control of growth, adhesion, and differentiation of cells in numerous tissues. TGFβ has potent inhibitory effects on many lymphocyte responses; we also found that TGFβ could inhibit in vitro generation of tumor-specific CTL. Suppression was largely reversed with exogenous IL-2. Proliferation of memory-stage CTL clones was also inhibited by TGFβ, while the upregulation of cytotoxicity was not inhibited by TGFβ. These studies suggested that TGFβ limited anti-tumor CTL responses via both an indirect effect on IL-2 production, and by a direct effect on proliferation of memory CTL.
In CTLL-2 cells, …
Virginia Dental Journal (Vol. 70, No. 4, 1993)
Virginia Dental Journal (Vol. 70, No. 4, 1993)
Virginia Dental Journal
No abstract provided.
Characterization Of A Promoter Rearrangement And A Second Promoter In The Human C-Myb Proto-Oncogene, Sarah Margaret Jacobs
Characterization Of A Promoter Rearrangement And A Second Promoter In The Human C-Myb Proto-Oncogene, Sarah Margaret Jacobs
Theses and Dissertations
The human cellular proto-oncogene c-myb has been implicated as important in the regulation of hematopoietic cell growth and differentiation. Aberrant expression of this gene and chromosomal aberrations near the c-myb locus have been associated with a number of carcinogenic processes. An alternatively spliced CDNA clone of c-myb, pMbm-2, contains unique 5’ sequences which replace exon 1. The existence of this 5’ divergent CDNA clone led us into a study of the promoter activity of the c-myb gene.
Intron 1 of c-myb is highly conserved between human and mouse throughout the intron, while only those sequences directly adjacent to exons …
Mechanisms Of Complement Resistance By Pathogenic Naegleria Fowleri Amoebae, Denise Marie Toney
Mechanisms Of Complement Resistance By Pathogenic Naegleria Fowleri Amoebae, Denise Marie Toney
Theses and Dissertations
The genus Naegleria is composed of a distinct group of free-living amoeboflagellates that include both pathogenic and nonpathogenic species. N. fowleri, the only pathogenic species of Naegleria to be isolated from humans, is the etiological agent of primary amoebic meningoencephalitis, a rare but rapidly fatal disease of the central nervous system in humans and in laboratory animals. The mechanisms of pathogenicity and the determinants of virulence of N. fowleri are unknown. Both pathogenic and nonpathogenic Naegleria activate the alternative complement pathway, however pathogenic N. fowleri are complement-resistant and nonpathogenic N. gruberi are complement-sensitive. The ability to resist complement-mediated lysis …
Perceived Importance Of Clinical Teaching Characteristics For Nurse Anesthesia Clinical Faculty, William Hartland Jr.
Perceived Importance Of Clinical Teaching Characteristics For Nurse Anesthesia Clinical Faculty, William Hartland Jr.
Theses and Dissertations
This study examined the perceived importance of the 22 characteristic of effective clinical instructors as identified by- Katz in 1982. The effect of various demographic variables on these perceived values of importance was also investigated.
Data were collected by means of a questionnaire survey instrument. A random sample of 354 nurse anesthesia program directors, CRNA clinical instructors and nurse anesthesia students from across the United States participated in this study. A 73 percent return rate was achieved.
Characteristic mean scores of importance demonstrate that respondents perceived all 22 characteristics as either "very important" or "highly important." When all 22 characteristic …
Relationships Among The Distribution Of Terminal Fields Of Sensory Afferent Projections To The Deep Layers Of The Superior Colliculus Within The Cat, Wayne Thomas Shaia
Relationships Among The Distribution Of Terminal Fields Of Sensory Afferent Projections To The Deep Layers Of The Superior Colliculus Within The Cat, Wayne Thomas Shaia
Theses and Dissertations
While it is well known that the different sensory modalities are primarily represented at separate locations within the central nervous system, there are numerous sites in which information from the different sensory modalities converge. Perhaps the best known structure where inputs from different sensory modalities converge is the superior colliculus. Here, not only are visual, auditory and somatosensory inputs present, but they also form organized representations of auditory and visual space as well a map of the body surface in addition, neurons that receive inputs from more than one sensory modality (i.e. multisensory) are found here in abundance. Although a …
Sjögren-Larsson Syndrome: Genetic Studies And Biochemical Characterization Of Human Fatty Aldehyde Dehydrogenase, Todd L. Kelson
Sjögren-Larsson Syndrome: Genetic Studies And Biochemical Characterization Of Human Fatty Aldehyde Dehydrogenase, Todd L. Kelson
Theses and Dissertations
Sjögren-Larsson syndrome (SLS) is an autosomal recessive disorder due to deficiency of the fatty aldehyde dehydrogenase (FALDH) component of fatty alcohol:NAD+ oxidoreductase (FAO). We investigated the enzymatic defect in SLS in order to elucidate the role of FALDH in fatty aldehyde and fatty alcohol metabolism.
Genetic studies were performed to investigate carrier detection for SLS. Cultured skin fibroblasts from normal controls, SLS obligate heterozygotes, and SLS homozygotes were assayed for FAO and FALDH activities using 18-carbon substrates. In SLS homozygotes, mean FAO and FALDH activities were 8% of normal, and there was no overlap between the homozygote and heterozygote …
Identification Of Regulatory Mechanisms Of Genes Encoding Citrate Synthase In The Yeast Saccharomyces Cerevisiae, Christine Smith Kell
Identification Of Regulatory Mechanisms Of Genes Encoding Citrate Synthase In The Yeast Saccharomyces Cerevisiae, Christine Smith Kell
Theses and Dissertations
The major aim of this research was to investigate the molecular mechanisms of regulation of transcription of CIT1 and CIT2, the genes encoding citrate synthase in yeast. Specifically addressed are the questions of (1) localization of cis-acting sites required for expression or regulation, (2) the roles of HAP1 and HAP2,3,4 in expression of both genes, (3) identification of other trans-acting factors involved in expression of either gene, (4) localization of cis-acting sites involved in up regulation of CIT2 in response to disruption of CIT1 or rho° status (Liao et al., 1991; Liao and Butow, 1993).
I show here that mutations …
Subjectivity Of Estimating Blood Loss Among Health Care Providers In The Operating Room, Hugh Andrew Siegel
Subjectivity Of Estimating Blood Loss Among Health Care Providers In The Operating Room, Hugh Andrew Siegel
Theses and Dissertations
This research utilized a descriptive study to establish a relationship between educational background and accuracy of estimating blood loss. The null hypothesis, that the educational background of health care providers in the operating room has no effect on the accuracy of estimating blood loss , was tested. Ten nurse anesthesia students, 8 certified registered nurse anesthetists, 16 operating room registered nurses, 12 anesthesiologists, and 9 surgeons were included in the sample population. A number of different protocols were utilized to assess the relative accuracy of blood volumes estimates. The study was separated into four stations. Station 1 consisted of three …
Comparison Of Succinylcholine Induced Fasciculation Attenuation With Defasciculating Doses Of Vecuronium And Mivacurium Based On Ideal Body Weight, Marvin E. Early
Comparison Of Succinylcholine Induced Fasciculation Attenuation With Defasciculating Doses Of Vecuronium And Mivacurium Based On Ideal Body Weight, Marvin E. Early
Theses and Dissertations
This study was conducted to determine if Mivacurium (Miv) was as effective as Vecuronium (Vec) in attenuating Succinylcholine (Sch)-induced fasciculations with muscle relaxant doses based upon ideal body weight (IBW). A quasi experimental design was used to study 60 patients who were randomly assigned to one of three groups. The two study groups were compared to a control group and each other with regards to the incidence and intensity of fasciculations. Either Vec (0.01 mg/kg (IBW)), Miv (0.02 mg/kg (IBW)), or saline (control) was administered in a double-blinded manner 3 minutes prior an intubating dose of Sch (IBW). Both pretreatment …
Reflections In Ink (1992-12-14)
Reflections In Ink (1992-12-14)
Reflections in Ink, 1978-1994
Reflections in Ink was an alternative newspaper began through collaboration of the Black Student Alliance and the VCU student branch of the League of Black Journalists, that published from 1978 to 1993 before changing its name to The Vine.
Vcu Voice (1992-12-11)
VCU Voice, 1988-1998
VCU Today, the University’s first official administrative organ, began as a somewhat irregular monthly publication but moved to a bi-weekly newspaper format in the 1980s. The newspaper changed its name to VCU Voice in 1988 and ten years later it appeared under the title UniverCity News. As it neared the end of its run as a physical newspaper, the publication became simply VCU News. These four publications were essentially the same periodical published under different titles by the Office of University Relations. VCU News appeared online for the first time in 2002.
Vcu Voice (1992-11-30)
VCU Voice, 1988-1998
VCU Today, the University’s first official administrative organ, began as a somewhat irregular monthly publication but moved to a bi-weekly newspaper format in the 1980s. The newspaper changed its name to VCU Voice in 1988 and ten years later it appeared under the title UniverCity News. As it neared the end of its run as a physical newspaper, the publication became simply VCU News. These four publications were essentially the same periodical published under different titles by the Office of University Relations. VCU News appeared online for the first time in 2002.
[1992-11-19] Minutes Of A Regular Meeting Of The Board Of Visitors Of Virginia Commonwealth University November 19, 1992., Virginia Commonwealth University. Board Of Visitors
[1992-11-19] Minutes Of A Regular Meeting Of The Board Of Visitors Of Virginia Commonwealth University November 19, 1992., Virginia Commonwealth University. Board Of Visitors
VCU Board of Visitors Minutes
Official minutes of the VCU Board of Visitors and its Executive Committee.
Vcu Voice (1992-11-13)
VCU Voice, 1988-1998
VCU Today, the University’s first official administrative organ, began as a somewhat irregular monthly publication but moved to a bi-weekly newspaper format in the 1980s. The newspaper changed its name to VCU Voice in 1988 and ten years later it appeared under the title UniverCity News. As it neared the end of its run as a physical newspaper, the publication became simply VCU News. These four publications were essentially the same periodical published under different titles by the Office of University Relations. VCU News appeared online for the first time in 2002.
Commonwealth Times 1992-11-05 Election '92 : A Special Supplement To The Commonwealth Times
Commonwealth Times 1992-11-05 Election '92 : A Special Supplement To The Commonwealth Times
Commonwealth Times, 1969-
No abstract provided.
Vcu Magazine (1992-11)
VCU Magazine, 1971-1993
A publication for alumni and friends of Virginia Commonwealth University.
Vcu Voice (1992-10-30)
VCU Voice, 1988-1998
VCU Today, the University’s first official administrative organ, began as a somewhat irregular monthly publication but moved to a bi-weekly newspaper format in the 1980s. The newspaper changed its name to VCU Voice in 1988 and ten years later it appeared under the title UniverCity News. As it neared the end of its run as a physical newspaper, the publication became simply VCU News. These four publications were essentially the same periodical published under different titles by the Office of University Relations. VCU News appeared online for the first time in 2002.